Fight Aging! Newsletter, November 23rd 2020

In conclusion, the study indicates that HBOT may induce significant senolytic effects that include significantly increasing telomere length and clearance of senescent cells in the aging populations. Data on the Prevalence of Liver Fibrosis in Middle Age https://www.fightaging.org/archives/2020/11/data-on-the-prevalence-of-liver-fibrosis-in-middle-age/ Fibrosis is a consequence of age-related disarray in tissue maintenance processes, leading to the deposition of scar-like collagen that disrupts tissue structure and function. It is an ultimately fatal issue for which there are only poor treatment options at present. Hopefully that will change with further exploration of the relationship between accumulation of senescent cells in aged tissues and the development of fibrosis. In mice, the use of senolytic therapies to selectively destroy senescent cells has reversed fibrosis in a number of different organs. A substantial minority of participants from the Framingham Heart Study, (nearly nine percent), had potentially clinically significant liver fibrosis (scarring). This the first study of this size and scale done in the United States. More than 3,000 middle-aged Framingham Heart Study participants (over a three-year period) underwent a test or vibration-controlled transient elastography that quantifies how much fat is in the liver and also measures the stiffness of the liver. Liver stiffness correlates with the degree of liver scarring. "We found ...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs

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Rallis Viral skin infections often affect the sports community. The aim of this study was to assess the rates, location sites, and seasons of appearance of common viral cutaneous diseases in beach volleyball athletes in Greece. Five hundred and forty-nine beach volleyball athletes participated in this study. The average age was 28.4 years. The viral infections were herpes simplex (type 1), molluscum contagiosum and warts. The measured parameters included: gender, age, the season when athletes may be more susceptible to infections and the location of infection in the body. Practicing information such as the number of t...
Source: Viruses - Category: Virology Authors: Tags: Communication Source Type: research
Abe Oudshoorn, Tanya Benjamin, Tracy A. Smith-Carrier, Sarah Benbow, Carrie Anne Marshall, Riley Kennedy, Jodi Hall, C. Susana Caxaj, Helene Berman, Deanna Befus Housing, Care and Support, Vol. ahead-of-print, No. ahead-of-print, pp.- People experiencing homelessness are uniquely vulnerable to the impacts of a pandemic, such as COVID-19. Therefore, governments across Canada have been implementing a patchwork of responses to address the needs of those who are homeless at this time. The purpose of this study is to both compile and assess the varying responses by exploring the breadth of actions presented i...
Source: Housing, Care and Support - Category: International Medicine & Public Health Authors: Source Type: research
Hello everyone! Non-traditional student here, 30 y/o now. Metrics: - started from CC, transferred to UC (didn't do so great in UC) - current AMCAS cGPA: 3.35, sGPA: 3.23; AACOMAS cGPA: 3.35, sGPA: 3.15 (this is after 28 credits of DIY post bacc at a community college) - DIY post bacc at CC consisted of: (Kinesiology, Intro to the Human Body, Human Physiology, Human Anatomy, Human Nutrition, Immunology, Microbiology) -- all at 4.0 - 1700+ hours of academic science research (co-author of a... Read more
Source: Student Doctor Network - Category: Universities & Medical Training Authors: Tags: Pre-Medical (DO) Source Type: forums
ConclusionSuturing technique has no significant effect on the surgical outcomes assessed regardless of open or laparoscopic technique.
Source: Pediatric Surgery International - Category: Surgery Source Type: research
ConclusionThere is no association between early initiation of adjuvant chemotherapy and post-operative complications including wound healing. Early initiation of chemotherapy ( ≤ 7 days) is feasible in unilateral WT or high-risk neuroblastoma patients who are otherwise doing well without resulting in a preponderance of wound healing complications.
Source: Pediatric Surgery International - Category: Surgery Source Type: research
AbstractPurposeWe aimed to clarify the frequency and the clinical significance of deviation of the uterus in female pediatric inguinal hernia.MethodsWe retrospectively evaluated the data of 94 female pediatric inguinal hernia cases that were treated by laparoscopic percutaneous extraperitoneal closure. We assessed for correlations between uterine deviation and age, body weight, the size of the hernia orifice, and the presence of contralateral processus vaginalis (PV) patency.ResultsEighty-four of 94 cases were diagnosed with unilateral inguinal hernia. A total of 62 (73.8%) of these had uterine deviation to the hernia side...
Source: Pediatric Surgery International - Category: Surgery Source Type: research
ConclusionsEvidence is limited regarding the efficacy and safety of intraoperative TAT placement in neonates with CDO. Well-designed RCTs are needed to address the issue definitively.
Source: Pediatric Surgery International - Category: Surgery Source Type: research
ConclusionThe national birth prevalence for omphalocele in Sweden is 1/10,000 newborn, with high termination rates. Over half of the pregnancies with prenatally diagnosed omphalocele will be terminated. Among those who continue the pregnancy, 1-year survival rates are high.Type of studyNational register studyLevel of evidenceIII.
Source: Pediatric Surgery International - Category: Surgery Source Type: research
ConclusionThere were no differences in short or long-term mortality between four university hospitals in Finland. However, some inter-hospital variation in postoperative outcomes was present.Level of evidenceLevel III.
Source: Pediatric Surgery International - Category: Surgery Source Type: research
ConclusionIn the follow-up of children and adolescents with CCM during the first UK lockdown using telemedicine we found that over half had stable health conditions. Patients needing additional care could not be predicted by the severity of their disease or their bowel function alone.
Source: Pediatric Surgery International - Category: Surgery Source Type: research
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