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Biochemical networks mapped in midgut of Aedes aegypti mosquitoes
(Colorado State University) Scientists have mapped for the first time the midgut metabolites of the Aedes aegypti, the mosquito that can transmit viruses that cause dengue, Zika, chikungunya and yellow fever to humans. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - February 15, 2018 Category: Infectious Diseases Source Type: news

Genetics makes Asians, Europeans susceptible to dengue shock syndrome
(PLOS) As globalization and climate change spread tropical diseases around the globe, not all populations are equally susceptible to infection. Gene variants common in people of Asian and European ancestry, for instance, make them more prone than those of African origin to developing severe dengue shock syndrome, according to a new study in PLOS Neglected Tropical Diseases. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - February 15, 2018 Category: Infectious Diseases Source Type: news

Sanofi bets on India with portfolio of drugs for diabetes, rare diseases
Sanofi reported one of the sharpest falls in its global sales in the fourth quarter, owing to the decline in diabetes drug sales, a controversial dengue vaccination settlement. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - February 13, 2018 Category: Pharmaceuticals Source Type: news

Triple whammy: You can get dengue, malaria, chikungunya at the same time
Researchers at Jamia Millia Islamia (JMI) have reported two such cases in the medical journals Intervirology and Virus Disease. (Source: The Economic Times)
Source: The Economic Times - February 11, 2018 Category: Consumer Health News Source Type: news

Kenya:'Chikungunya and Dengue Fever Contained'
[Nation] Chikungunya and dengue fever, two painful and debilitating mosquito-borne diseases that broke out in Mombasa in December have been contained. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - February 10, 2018 Category: African Health Source Type: news

Safety blunders expose lab staff to potentially lethal diseases in UK
Exclusive: breaches investigated involve dengue virus, anthrax and other deadly pathogensSafety breaches at UK labs that handle harmful bacteria, viruses and fungi have spread infections to staff and exposed others to potentially lethal diseases, the Guardian has learned.The Health and Safety Executive (HSE) has investigated a series of mistakes over the past two years that led to scientists falling ill at specialist labs run by hospitals, private companies, and even Public Health England (PHE), the government agency which exists to protect and improve the nation ’s health and wellbeing.Continue reading... (Source: G...
Source: Guardian Unlimited Science - February 10, 2018 Category: Science Authors: Ian Sample Science editor Tags: Infectious diseases Science Microbiology Medical research Source Type: news

ID Break: Herpes Down in U.S.; $500 Billion Pandemics; Deadly Dengue Vax?
(MedPage Today) -- News and commentary from the world of infectious diseases (Source: MedPage Today Public Health)
Source: MedPage Today Public Health - February 7, 2018 Category: American Health Source Type: news

Sanofi: No proof that vaccine linked to Philippines deaths
Drugmaker Sanofi insists there is no evidence of a link between the world's first dengue vaccine and children's deaths in the Philippines (Source: ABC News: Health)
Source: ABC News: Health - February 7, 2018 Category: Consumer Health News Tags: Health Source Type: news

Philippine lawyers sue Sanofi over dengue vaccine
MANILA (Reuters) - A Philippine government agency on Monday filed a lawsuit against French drugmaker Sanofi demanding compensation for the parents of a 10-year-old girl the agency said had died as a result of receiving its controversial anti-dengue vaccine. (Source: Reuters: Health)
Source: Reuters: Health - February 5, 2018 Category: Consumer Health News Tags: healthNews Source Type: news

Sanofi rejects Philippine plea for refund on used vaccines
A Sanofi Pasteur official says the French drugmaker cannot comply with a request by Philippine officials for a refund of dengue vaccines injected on more than 830,000 children because it would imply that the drug is ineffective (Source: ABC News: Health)
Source: ABC News: Health - February 5, 2018 Category: Consumer Health News Tags: Health Source Type: news

Philippines gripped by dengue vaccine fears
Fears over a dengue vaccine lead to a big drop in immunisation rates for preventable diseases. (Source: BBC News | Health | UK Edition)
Source: BBC News | Health | UK Edition - February 3, 2018 Category: Consumer Health News Source Type: news

Philippines says anti-dengue vaccine may be connected to three deaths
MANILA (Reuters) - The Philippines said on Friday the anti-dengue vaccine Dengvaxia may be connected to three deaths in the country, according to a government-ordered inquiry, and that the drug is not ready for mass immunization. (Source: Reuters: Health)
Source: Reuters: Health - February 2, 2018 Category: Consumer Health News Tags: healthNews Source Type: news

Philippines: 3 deaths may be linked to dengue vaccinations
Philippine health officials say the deaths of three children inoculated with a Sanofi Pasteur dengue vaccine may have "causal association" to the inoculation and two of the children may have died because the vaccine failed (Source: ABC News: Health)
Source: ABC News: Health - February 2, 2018 Category: Consumer Health News Tags: Health Source Type: news

Dengue fever may strike large parts of Europe
Dr Jing Helmersson, an epidemologist at Umea University, Sweden, warns rising temperatures are encouraging killer mosquitos that carry the incurable disease to spread north. (Source: the Mail online | Health)
Source: the Mail online | Health - February 1, 2018 Category: Consumer Health News Source Type: news

How Sanofi's Setback Could Lead to Better Dengue Vaccines How Sanofi's Setback Could Lead to Better Dengue Vaccines
New dengue vaccines being developed by Takeda Pharmaceuticals Co Ltd and U.S. government scientists are poised to provide a safer alternative to Sanofi's Dengvaxia, according to vaccine experts, because they already take into account some of the issues that sidelined the product last year.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - January 30, 2018 Category: Consumer Health News Tags: Infectious Diseases News Source Type: news

How Sanofi's setback could lead to better dengue vaccines
CHICAGO (Reuters) - New dengue vaccines being developed by Takeda Pharmaceuticals Co Ltd and U.S. government scientists are poised to provide a safer alternative to Sanofi's Dengvaxia, according to vaccine experts, because they already take into account some of the issues that sidelined the product last year. (Source: Reuters: Health)
Source: Reuters: Health - January 29, 2018 Category: Consumer Health News Tags: healthNews Source Type: news

Link found between genes in mosquitos and the spread of diseases
(University of Missouri-Columbia) Researchers at the University of Missouri have found a link between genetic molecules in mosquitos and dengue fever. The results of the study, conducted by Susanta K. Behura and his colleagues, could lead to future breakthroughs in combating destructive tropical diseases like dengue fever, Zika virus and yellow fever. The researchers focused their efforts on a single species of mosquito, Aedes aegypti, a key player in the spread of such diseases in animals and humans around the world. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - January 24, 2018 Category: International Medicine & Public Health Source Type: news

10 Global Health Issues to Watch in 2018
January 19, 2018It ’s notallbad news.When we set out to compile our annual list of global health issues to watch this year, it seemed like all bad news. And true, that ’s often what we deal with in global health—the problems that need tackling, the suffering we can help alleviate.But then stories and columns likethis one cheer us up. They remind us that no matter how complicated and frustrating our work may get, fighting back against poverty and inequality works.There are and always will be global health challenges to face. But there ’s boundless hope, too. And a field full of determined health work...
Source: IntraHealth International - January 19, 2018 Category: International Medicine & Public Health Authors: mnathe Source Type: news

Unilateral Sacroiliitis Following Dengue Virus Infection Unilateral Sacroiliitis Following Dengue Virus Infection
Might dengue virus be linked with the development of arthritis in the same manner as other arthritogenic viruses?Journal of Medical Case Reports (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - January 15, 2018 Category: Consumer Health News Tags: Infectious Diseases Journal Article Source Type: news

After Fortis, health panel to probe Medanta
Medanta authorities said they will cooperate in the probe. “Saurya was given the best treatment for dengue shock syndrome and other complications. (Source: The Economic Times)
Source: The Economic Times - January 13, 2018 Category: Consumer Health News Source Type: news

Philippines exhumes bodies of two children in dengue vaccine probe
MANILA (Reuters) - A Philippine government agency on Thursday exhumed the bodies of two children whose parents suspect they died of dengue after receiving a new vaccine against the disease, although its maker said it was not known to have caused any deaths in the country. (Source: Reuters: Health)
Source: Reuters: Health - January 11, 2018 Category: Consumer Health News Tags: healthNews Source Type: news

Dengue takes low and slow approach to replication
(Duke University) Dengue virus slowly takes over the endoplasmic reticulum, the production site for a subset of host proteins, and steers clear of the cytosol, the fluid-filled space where the majority of host cellular proteins are synthesized. Its viral RNA template is translated into protein in such an inefficient, lackadaisical manner that it doesn't trip alarms. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - January 11, 2018 Category: Infectious Diseases Source Type: news

Philippines fines Sanofi, suspends clearance for Dengvaxia
MANILA (Reuters) - The Philippines has suspended clearance for Sanofi's dengue vaccine Dengvaxia and fined the French drugmaker a symbolic $2,000 citing violations on product registration and marketing, the health secretary said on Thursday. (Source: Reuters: Health)
Source: Reuters: Health - January 4, 2018 Category: Consumer Health News Tags: healthNews Source Type: news

Philippines fines Sanofi, suspends clearance for Dengvaxia
MANILA (Reuters) - The Philippines has fined Sanofi $2,000 and suspended clearance for the French drug maker's controversial dengue vaccine Dengvaxia, citing violations on product registration and marketing, its health secretary said on Thursday. (Source: Reuters: Health)
Source: Reuters: Health - January 4, 2018 Category: Consumer Health News Tags: healthNews Source Type: news

Dengue vaccination cost  effective in endemic countries
(Source: PharmacoEconomics and Outcomes News)
Source: PharmacoEconomics and Outcomes News - January 1, 2018 Category: Drugs & Pharmacology Source Type: news

Sudan:Dozens of Dengue Fever Cases Across Sudan
[Radio Dabanga] Khartoum -According to the World Health Organization (WHO), the Sudanese Ministry of Health has recently reported an increase in the number of suspected dengue fever cases during the period between 2 October and 8 December. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - December 27, 2017 Category: African Health Source Type: news

Updated Questions and Answers Related to the Dengue Vaccine Dengvaxia ® and Its Use
World Health Organization. 12/22/2017 The questions and answers on this Web page supplement the World Health Organization (WHO) position paper on the dengue vaccine Dengvaxia ® from July 2016. The WHO Secretariat recommends that the July 2016 position paper be read in conjunction with this resource, which discusses dengue, the vaccine, and the results of additional analyses about the vaccine. (Text) (Source: Disaster Lit: Resource Guide for Disaster Medicine and Public Health)
Source: Disaster Lit: Resource Guide for Disaster Medicine and Public Health - December 22, 2017 Category: International Medicine & Public Health Authors: The U.S. National Library of Medicine Source Type: news

T cell-inducing dengue vaccines may better protect children of vaccinated mothers
(National University of Singapore, Yong Loo Lin School of Medicine) Although maternal antibodies help to protect babies against dengue virus infection, they can also be detrimental. In some situations, maternal antibodies can enhance the severity of dengue infections in babies or interfere with immunization of the babies. NUS Medicine researchers have now shown that, in the face of such complications, a dengue vaccine that provokes a strong killer T cell response in these children can provide better and broader protection than vaccines inducing mainly antibodies. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - December 22, 2017 Category: Infectious Diseases Source Type: news

Rein in MRP or government will, syringe makers told
The NPPA had issued notice to the hospital following allegations of over-charging by the parents of the girl who died after leaving the hospital following dengue treatment for over two weeks. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - December 21, 2017 Category: Pharmaceuticals Source Type: news

Safety concerns derail dengue vaccination program
(Source: ScienceNOW)
Source: ScienceNOW - December 21, 2017 Category: Science Authors: Normile, D. Tags: In Depth Source Type: news

Canary Islands hotspot faces a deadly outbreak of dengue
Concerned health officials in Fuerteventura, off the coast of Africa, have discovered the mosquito responsible for the two killer infections. Scores of homes on the island are now being fumigated. (Source: the Mail online | Health)
Source: the Mail online | Health - December 20, 2017 Category: Consumer Health News Source Type: news

Dengue vaccine does NOT protect against the disease but actually puts you at HIGHER RISK of contracting it
(Natural News) The World Health Organization (WHO) reports that Dengue, a mosquito-borne viral infection common in tropical and sub-tropical areas across the globe, has become increasingly prevalent in recent years, with about half the world’s population at risk of the disease. The WHO notes that a dengue vaccine is available for use in people between... (Source: NaturalNews.com)
Source: NaturalNews.com - December 18, 2017 Category: Consumer Health News Source Type: news

Drug Company Under Fire After Revealing Dengue Vaccine May Harm Some
A promising vaccine for dengue fever is in limbo after the Philippines suspended its use amid widespread public anger and fears about its safety. (Source: NYT Health)
Source: NYT Health - December 17, 2017 Category: Consumer Health News Authors: DENISE GRADY and KATIE THOMAS Tags: Dengue Fever Vaccination and Immunization Philippines Source Type: news

Former Philippine President defends controversial dengue program
MANILA (Reuters) - Former Philippine President Benigno Aquino defended on Thursday his decision to implement a controversial immunization program using a new dengue vaccine in 2016, saying it was justified with millions of people at risk of being infected by the virus. (Source: Reuters: Health)
Source: Reuters: Health - December 14, 2017 Category: Consumer Health News Tags: healthNews Source Type: news

New drug thwarts Zika, dengue, West Nile in cell cultures
Lab tests prove a new drug called NGI-1 is capable of thwarting flaviviruses, the family that includes mosquito-borne viruses like Zika, dengue and West Nile. (Source: Health News - UPI.com)
Source: Health News - UPI.com - December 13, 2017 Category: Consumer Health News Source Type: news

Philippines' Duterte says dengue campaign carried out in 'good faith'
MANILA (Reuters) - President Rodrigo Duterte believes the previous Philippine government acted in good faith in launching an immunization drive that used a new dengue vaccine on hundreds of thousands of children, he said on Wednesday. (Source: Reuters: Health)
Source: Reuters: Health - December 13, 2017 Category: Consumer Health News Tags: healthNews Source Type: news

France's Sanofi pins hopes on new drugs after setbacks
PARIS (Reuters) - French pharmaceuticals group Sanofi said on Wednesday it had suffered from low uptake for a new cholesterol drug and from concerns about a dengue vaccine, but expressed confidence its pipeline of new products would support long-term growth. (Source: Reuters: Health)
Source: Reuters: Health - December 13, 2017 Category: Consumer Health News Tags: healthNews Source Type: news

Did Sanofi, WHO ignore warning signals on dengue vaccine?
CHICAGO/LONDON (Reuters) - When French drugmaker Sanofi published the results of clinical trials of children given its dengue vaccine two years ago, the overall findings were that it protected against the world's biggest and fastest growing mosquito-borne disease. (Source: Reuters: Health)
Source: Reuters: Health - December 13, 2017 Category: Consumer Health News Tags: healthNews Source Type: news

Philippines Defied Experts' Advice in Pursuing Dengue Immunization Program Philippines Defied Experts' Advice in Pursuing Dengue Immunization Program
As she announced in January 2016 that the Philippines would immunize one million children with a new dengue vaccine, the nation's then health secretary Janette Garin boasted it was a world-first and a tribute to her country's"expertise" in research.Reuters Health Information (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - December 12, 2017 Category: Consumer Health News Tags: Medscape Today News Source Type: news

Drug blocks Zika and dengue viruses in study
The small-molecule inhibitor, named NGI-1, shows promise as a treatment for Zika, dengue, West Nile, and yellow fever viruses. (Source: Yale Science and Health News)
Source: Yale Science and Health News - December 12, 2017 Category: Universities & Medical Training Source Type: news

Mosquito sex protein could provide key to controlling disease
(Rockefeller University) A protein transferred from male to female mosquitoes during sex influences female mating behavior -- a phenomenon that could be exploited to limit the spread of mosquito-borne illnesses like Zika and dengue. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - December 12, 2017 Category: International Medicine & Public Health Source Type: news

Philippines to Seek Refund of $59 Mln From Sanofi Amid Vaccine Risk Philippines to Seek Refund of $59 Mln From Sanofi Amid Vaccine Risk
The Philippines will seek the return of 3 billion pesos ($59 million) it paid French drugmaker Sanofi for a dengue vaccine used to immunize hundreds of thousands of children that Sanofi has said could worsen the disease in some cases.Reuters Health Information (Source: Medscape Allergy Headlines)
Source: Medscape Allergy Headlines - December 11, 2017 Category: Allergy & Immunology Tags: Public Health & Prevention News Source Type: news

Exclusive: Philippines defied experts' advice in pursuing dengue immunization program
MANILA (Reuters) - As she announced in January 2016 that the Philippines would immunize one million children with a new dengue vaccine, the nation's then health secretary Janette Garin boasted it was a world-first and a tribute to her country's "expertise" in research. (Source: Reuters: Health)
Source: Reuters: Health - December 10, 2017 Category: Consumer Health News Tags: healthNews Source Type: news

Philippines to seek refund of $59 million from Sanofi amid vaccine risk
MANILA (Reuters) - The Philippines will seek the return of 3 billion pesos ($59 million) it paid French drugmaker Sanofi for a dengue vaccine used to immunize hundreds of thousands of children that Sanofi has said could worsen the disease in some cases. (Source: Reuters: Health)
Source: Reuters: Health - December 8, 2017 Category: Consumer Health News Tags: healthNews Source Type: news

Philippines wants money back from Sanofi for dengue vaccine
The Philippine health chief says the government will demand a refund of $69.5 million from vaccine maker Sanofi Pasteur and look at possible legal action after a study showed its dengue vaccine could expose some people to severe illness (Source: ABC News: Health)
Source: ABC News: Health - December 8, 2017 Category: Consumer Health News Tags: Health Source Type: news

Philippines wants money back from Sanofi over dengue vaccine
The Philippines will demand a refund of $59 million from Sanofi Pasteur and look at possible legal action after a study showed the dengue vaccine used in a local immunization program could expose some people to severe illness (Source: ABC News: Health)
Source: ABC News: Health - December 8, 2017 Category: Consumer Health News Tags: Health Source Type: news

Philippines threatens Sanofi with legal action over dengue vaccine
Minister says French drugmaker will be held accountable over risks of Dengvaxia (Source: FT.com - Drugs and Healthcare)
Source: FT.com - Drugs and Healthcare - December 7, 2017 Category: Pharmaceuticals Source Type: news

Common fungus helps dengue virus thrive in mosquitoes
(Johns Hopkins University Bloomberg School of Public Health) A species of fungus that lives in the gut of some Aedes aegypti mosquitoes increases the ability of dengue virus to survive in the insects, according to a study from researchers at Johns Hopkins Bloomberg School of Public Health. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - December 7, 2017 Category: International Medicine & Public Health Source Type: news

Sanofi continues to seek clinical trial waiver in India for controversial dengue vaccine
Phase 3 trials are the last phase of clinical trials that a company conducts before it receives approval to market the drug here. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - December 5, 2017 Category: Pharmaceuticals Source Type: news

Philippines halts sale of dengue vaccine as Sanofi downplays risk
MANILA/LONDON (Reuters) - The Philippines has ordered French drugmaker Sanofi to stop the sale, distribution and marketing of its Dengvaxia dengue vaccine in the country after the company last week warned it could worsen the disease in some cases. (Source: Reuters: Health)
Source: Reuters: Health - December 5, 2017 Category: Consumer Health News Tags: healthNews Source Type: news