Deaths from dengue fever in Paraguay spike to 16 under strained health system
Paraguay health officials said on Friday that deaths from dengue fever increased to 16 in the South American country's worst outbreak of the disease in the last decade, severely straining its health system. (Source: Reuters: Health)
Source: Reuters: Health - February 14, 2020 Category: Consumer Health News Tags: healthNews Source Type: news

Could 9 in 10 Cases of Dengue Be Prevented?
THURSDAY, Feb. 13, 2020 -- Scientists say that 90% of dengue cases could be slashed by artificially infecting mosquitoes. Dengue viruses are spread to people by infected mosquitoes. But infecting the insects with Wolbachia bacteria blocks the dengue... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - February 14, 2020 Category: General Medicine Source Type: news

Travel-Associated and Locally Acquired Dengue Cases - United States, 2010-2017
During 2010-2017, a total of 5,387 dengue cases were reported from U.S. states and the District of Columbia; 93% were travel-associated. (Source: CDC Morbidity and Mortality Weekly Report)
Source: CDC Morbidity and Mortality Weekly Report - February 13, 2020 Category: American Health Tags: Dengue Fever (DF) MMWR Morbidity & Mortality Weekly Report Mosquito-Borne Diseases Travelers' Health Source Type: news

Army Inches Closer To Develop Zika And Dengue Virus Vaccine
Mosquito-carried diseases such as the Zika virus and Dengue still continue to thrive in warm temperate parts of the world, but new US army research suggests we are on the cusp of figuring out a vaccine that could potentially work to fight both these infections. (Source: Forbes.com Healthcare News)
Source: Forbes.com Healthcare News - February 8, 2020 Category: Pharmaceuticals Authors: Dana Dovey, Contributor Source Type: news

New details on how a viral protein puts the brakes on virus replication
(Colorado State University) Researchers used computational chemistry, biochemistry and virology to uncover new information on how viruses such as West Nile, dengue and Zika replicate. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - February 7, 2020 Category: Infectious Diseases Source Type: news

Army-developed Zika vaccine induces potent Zika and dengue cross-neutralizing antibodies
(Walter Reed Army Institute of Research) A new study led by WRAIR scientists has shown for the first time that a single dose of an experimental Zika vaccine in a dengue-experienced individual can boost pre-existing flavivirus immunity and elicit protective cross-neutralizing antibody responses against both Zika and dengue viruses. Findings were published today in Nature Medicine. Three Phase 1 human clinical trials have shown ZPIV to be safe and well-tolerated in healthy adults and that it induced a robust immune response. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - February 3, 2020 Category: Infectious Diseases Source Type: news

Analysis of counts for cluster randomized trials: Negative controls and test-negative designs - Dufault SM, Jewell NP.
In cluster randomized trials (CRTs), the outcome of interest is often a count at the cluster level. This occurs, for example, in evaluating an intervention with the outcome being the number of infections of a disease such as HIV or dengue or the number of ... (Source: SafetyLit)
Source: SafetyLit - February 1, 2020 Category: International Medicine & Public Health Tags: Community-Based Prevention Source Type: news

Releasing artificially-infected mosquitoes could reduce global dengue cases by 90%
(Imperial College London) Releasing mosquitoes infected with a type of bacteria that prevents them transmitting dengue could cut cases of the disease by as much as 90%. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - January 29, 2020 Category: Infectious Diseases Source Type: news

UMD-led study named Science's most impactful paper of 2019
(University of Maryland) The American Association for the Advancement of Science (AAAS) awarded its 2019 Newcomb Cleveland Prize to University of Maryland entomologists Raymond St. Leger, Brian Lovett and their seven West African collaborators for their study describing the development and testing of a genetically engineered fungus to fight mosquito-borne diseases such as malaria, dengue& Zika. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - January 24, 2020 Category: International Medicine & Public Health Source Type: news

Malaria-fighting technology earns 2019 AAAS Newcomb Cleveland Prize
(American Association for the Advancement of Science) A team of nine researchers based in the United States and Burkina Faso will receive the 2019 Newcomb Cleveland Prize, presented by the American Association for the Advancement of Science, for the development of a promising tool in the global fight against malaria and other diseases transmitted by mosquitoes, including dengue and Zika. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - January 24, 2020 Category: International Medicine & Public Health Source Type: news

Dengue virus submission improvements now live!
When there is an outbreak of dengue fever in the world, it’s critical that viral genomic sequence data be submitted by researchers and made available to analyze as soon as possible.  You can now submit Dengue virus sequences to GenBank … Continue reading → (Source: NCBI Insights)
Source: NCBI Insights - January 23, 2020 Category: Databases & Libraries Authors: NCBI Staff Tags: What's New Dengue GenBank submissions viruses Source Type: news

A Zika vaccine could save suffering and costs
(CUNY Graduate School of Public Health and Health Policy) A new study led by researchers at the CUNY Graduate School of Public Health and Health Policy (CUNY SPH) and the National School of Tropical Medicine at Baylor College of Medicine found that routinely giving the Zika vaccine to women of childbearing age could save money if the risk of Zika is around that of other mosquito-borne diseases like dengue and chikungunya. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - January 23, 2020 Category: Infectious Diseases Source Type: news

Paraguay's President Abdo contracts dengue fever amid outbreak
A dengue fever outbreak that has affected thousands of Paraguayans in recent weeks has reached as far as the presidential palace, with the country's leader Mario Abdo confirmed as having been struck by the disease. (Source: Reuters: Health)
Source: Reuters: Health - January 22, 2020 Category: Consumer Health News Tags: healthNews Source Type: news

Mosquito-borne diseases could be prevented by skin cream
(University of Leeds) A skin cream used to treat warts and skin cancer could help protect people against viral diseases such as Zika and dengue, according to new research from the University of Leeds. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - January 22, 2020 Category: Infectious Diseases Source Type: news

The Irony of Finding So Many Exoplanets in a Time of Climate Change
There was nothing quite like the slang used in the early days of the space program. Saying something was “OK” would not do when you could say “A-OK” instead. Saying, “Let’s get moving,” when you’ve been sealed in your spacecraft for hours waiting to launch while Mission Control sorts out technical glitches, was weak tea compared to the “Light this candle!” as an exasperated Al Shepard barked in 1961. And then, too, there was “screw the pooch.” A cleaned-up version of a decidedly coarser term, it meant, in the pilot’s argot, to crash your jet or l...
Source: TIME: Science - January 21, 2020 Category: Science Authors: Jeffrey Kluger Tags: Uncategorized climate change newsletter Space Source Type: news

Paraguay braces for deadly Dengue fever outbreak
Paraguay is bracing for a potential major epidemic of Dengue fever after recording close to 7,000 suspected cases in the first two weeks of 2020, similar to levels in the severe 2013 outbreak that led to 250 deaths. (Source: Reuters: Health)
Source: Reuters: Health - January 17, 2020 Category: Consumer Health News Tags: healthNews Source Type: news

Scientists engineer dengue-resistant mosquitoes
Scientists at the University of California, San Diego, gave the insects human antibodies - attacker proteins from the immune system - which made them unable to spread dengue in a lab. (Source: the Mail online | Health)
Source: the Mail online | Health - January 17, 2020 Category: Consumer Health News Source Type: news

Researchers Alter Mosquitoes to Resist Dengue Infection
THURSDAY, Jan. 16, 2020 -- Mosquitoes that can't be infected by or spread dengue virus have been created by scientists. The researchers genetically engineered the mosquitoes to be resistant to all four types of dengue, a mosquito-borne virus that's... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - January 16, 2020 Category: General Medicine Source Type: news

Mauritius: Inter-Sectoral Collaboration Is Key to Control and Prevent Outbreak of Vector-Borne Diseases
[Government of Mauritius] 'An inter-sectoral collaboration is key to control and prevent the outbreak of vector-borne diseases such as malaria, dengue and chikungunya, in particular during the currently prevailing cyclonic and rainy season'. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - January 16, 2020 Category: African Health Source Type: news

Mosquitoes engineered to repel dengue virus
(University of California - San Diego) An international team of scientists has synthetically engineered mosquitoes that halt the transmission of the dengue virus. Led by biologists at UC San Diego, the researchers developed a human antibody for dengue suppression in Aedes aegypti mosquitoes, the insects that spread dengue. The development marks the first engineered approach in mosquitoes that targets the four known types of dengue, improving upon previous designs that addressed single strains. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - January 16, 2020 Category: Infectious Diseases Source Type: news

Sudan: 'Sudan Free of Dengue, Chikungunya' - Minister
[Radio Dabanga] Sudan -Sudan's Ministry of Health has declared that the country is free of dengue and Chikungunya for the first time since August 2019. The International Epidemiological Office of the World Organisation for Animal Health (OIE) has declared that livestock is also free of epidemic diseases in Sudan. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - January 6, 2020 Category: African Health Source Type: news

A Climate Change-Driven Dengue Outbreak Has Been Described As The Caribbean ’s ‘Worst Medical Crisis Ever’
The number of individuals in the Americas having contracted dengue is approaching 3 million with at least 1,372 recorded deaths — the highest number of cases ever on record. Experts have pointed to climate change as one of the leading causes for the surge in numbers. (Source: Forbes.com Healthcare News)
Source: Forbes.com Healthcare News - January 1, 2020 Category: Pharmaceuticals Authors: Daphne Ewing-Chow, Contributor Source Type: news

Asia's hardest year for dengue fever – in pictures
More than a million cases were reported in south-east Asia last year with poorer households most at riskThe global toll of dengue fever is becoming well known, with rising temperatures contributing to severe outbreaks that made 2019 the worst year on record for the disease.In 1970 only nine countries faced severe dengue outbreaks. But the disease, which is spread by mosquitoes that can only survive in warm temperatures, is now seen in more than 100 countries. There arethought to be 390m infections each yearContinue reading... (Source: Guardian Unlimited Science)
Source: Guardian Unlimited Science - December 30, 2019 Category: Science Authors: Photographer Luke Duggleby and journalist Laure Siegel Tags: Global development Global health Infectious diseases Medical research Science Source Type: news

Cellular culprit suspected of pushing dengue fever from bad to worse is cleared by transcripts
(La Jolla Institute for Immunology) No one knows what makes a mild dengue viral infection morph into a severe and sometimes deadly dengue hemorrhagic fever/dengue shock syndrome. Experts previously believed the likely cause was ramped up activity of T cells, which can massively boost an immune response to a virus. Now, researchers at the La Jolla Institute for Immunology (LJI), have found definitive evidence that CD4 T cells, one of two main subtypes of T cells, are not to blame. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - December 24, 2019 Category: International Medicine & Public Health Source Type: news

Addressing the Environmental Determinants of Health in Vector Surveillance and Control Strategies: Promoting Key Interventions
Source: World Health Organization, Pan American Health Organization (PAHO). Published: 12/18/2019. Climate change and other environmental changes are among the main factors that have led to the emergence or reemergence of vector-borne diseases, including dengue and Zika. This 21-page publication offers key interventions to promote vector surveillance and control activities that emphasize environmental health, using interprogrammatic and intersectoral approaches. (PDF) (Source: Disaster Lit: Resource Guide for Disaster Medicine and Public Health)
Source: Disaster Lit: Resource Guide for Disaster Medicine and Public Health - December 18, 2019 Category: International Medicine & Public Health Source Type: news

Probabilistic temporal prediction of the deaths caused by traffic in Colombia. Mortality caused by traffic prediction - Rodr íguez J, Jattin J, Soracipa Y.
BACKGROUND: from probability theory and probabilistic random walk, predictions about the quantity of cases of a given phenomenon for certain year, such as epidemics of dengue, have been previously obtained with results close to 100% in precision. O... (Source: SafetyLit)
Source: SafetyLit - December 17, 2019 Category: International Medicine & Public Health Tags: Engineering, Physics, Structural Soundness and Failure Source Type: news

Dengue fever finds breeding ground in war-weary Yemen
Ibrahim Ali al-Jadari's four teenage daughters lie at home on intravenous drips that will soon run out as they, like tens of thousands of other Yemenis, battle a seasonal surge of dengue fever. (Source: Reuters: Health)
Source: Reuters: Health - December 16, 2019 Category: Consumer Health News Tags: healthNews Source Type: news

Sudan: Dengue Fever Still On the Rise
[Radio Dabanga] East Sudan -The number of reported cases of Dengue fever continues to increase in Sudan, especially in Red Sea state. On Thursday, one person died, and 21 cases of infection were confirmed in Kassala. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - December 16, 2019 Category: African Health Source Type: news

Sudan: Malaria Breached Epidemic Threshold in 2019
[Radio Dabanga] Khartoum -More than 1.8 million cases of malaria were reported from across Sudan so far in 2019, a sharp increase compared to previous years, the UN Office for the Coordination of Humanitarian Affairs (OCHA) reported on Thursday. Cases of diphtheria, dengue fever, rift valley fever, chikungunya, and cholera continue to be recorded across the country, according to the Sudanese Ministry of Health. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - December 16, 2019 Category: African Health Source Type: news

Dengue fever – Afghanistan
On 1 May 2019, in response to increasing numbers of dengue fever cases in Pakistan and India, health authorities in Afghanistan heightened monitoring for the disease. As part of this increased vigilance, the Central Public Health Laboratory (CPHL) in Kabul began to broaden its investigation for possible cases of the disease, such as reviewing samples that tested negative for Crimean-Congo Hemorrhagic Fever (CCHF) to see if they were positive for dengue. The laboratory performed differential diagnosis and tests on 40 samples that had tested negative for Crimean-Congo Hemorrhagic Fever (CCHF). Between 1 October to 4 December...
Source: WHO Disease Outbreaks - December 13, 2019 Category: Infectious Diseases Tags: news Source Type: news

Safer viruses for vaccine research and diagnosis
(University of Queensland) A new technology to produce safer 'hybrid' viruses at high volumes for use in vaccines and diagnostics for mosquito-borne diseases has been developed at The University of Queensland.Researchers from UQ and QIMR Berghofer Medical Research Institute have exploited the benign characteristics of the Binjari virus - inert to humans - to produce 'dangerous looking' mosquito-borne viruses such as Zika and dengue, but which cannot grow in humans or animals. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - December 11, 2019 Category: Infectious Diseases Source Type: news

Sudan: Dengue Fever Declining in Eastern Sudan's Kassala
[Radio Dabanga] Kassala -Dengue fever rates in Kassala last week recorded a marked decline, ranging from 36 to 90 cases per day. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - December 9, 2019 Category: African Health Source Type: news

East Africa: EAC Manifests Zeal Against Top Diseases
[Daily News] THE East African Legislative Assembly (EALA) has adopted a report of the Committee on General Purpose on the oversight activity assessing levels of preparedness of partner states in management of epidemics, particularly Ebola and Dengue. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - December 6, 2019 Category: African Health Source Type: news

New tool to predict the global spread of dengue
(CSIRO Australia) Researchers at CSIRO, Australia's national science agency, QUT and Queensland Health have developed a new tool to predict the global spread of human infectious diseases, like dengue, and track them to their source. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - December 4, 2019 Category: International Medicine & Public Health Source Type: news

Mosquitoes bring ‘mystery illness’ to the mountain villages of Nepal
Rising temperatures linked to outbreaks of dengue fever high in the Kathmandu Valley, experts say•Global heating behind record number of cases of the diseaseLilawati Awasthi is used to the risks that come from living in a remote mountainous district in the far west of Nepal. Floods, landslides and treacherous roads are a part of daily life. But this year she faced a new hazard: mosquitoes carrying a mystery illness.When she began to feel sick in September she was not overly concerned at first. “I thought it was a simple fever, but it wouldn’t go away,” says the 50-year-old. “We went to the hosp...
Source: Guardian Unlimited Science - December 3, 2019 Category: Science Authors: Pete Pattisson and Roshan Sedhai in Kathmandu Tags: Nepal Infectious diseases Climate change Environment Global development South and Central Asia Microbiology Science World news Source Type: news

Dengue: Annual Epidemiological Report for 2018; Surveillance Report
Source: European Union, European Centre for Disease Prevention and Control (ECDC). Published: 12/2019. This seven-page report on cases of dengue is based on data for 2018 retrieved from The European Surveillance System (TESSy) on September 10, 2019. For 2018, 27 countries reported 2,191 cases of dengue, of which 2,033 (92.8 percent) were confirmed. Fourteen autochthonous dengue cases were reported from continental Europe by France and Spain. (PDF) (Source: Disaster Lit: Resource Guide for Disaster Medicine and Public Health)
Source: Disaster Lit: Resource Guide for Disaster Medicine and Public Health - December 1, 2019 Category: International Medicine & Public Health Source Type: news

Dengue fever –Spain
On 6 November 2019, the Spanish authorities reported a likely sexual transmission of dengue between two men who have sex with men (MSM) in the municipality of Madrid in central Spain. (Source: WHO Disease Outbreaks)
Source: WHO Disease Outbreaks - November 29, 2019 Category: Infectious Diseases Tags: news Source Type: news

Sudan: Dengue Fever Outbreak Shuts Sudan University
[Radio Dabanga] Kassala -In eastern Sudan, the University of Kassala announced the suspension of study and evaluations, owing to the spread of dengue fever in the city. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - November 28, 2019 Category: African Health Source Type: news

Bacteria-armed mosquitoes make dent in dengue
(Source: ScienceNOW)
Source: ScienceNOW - November 28, 2019 Category: Science Authors: Servick, K. Tags: Epidemiology, Medicine, Diseases, Microbiology In Depth Source Type: news

Misguided approach to dengue vaccine risk
(Source: ScienceNOW)
Source: ScienceNOW - November 28, 2019 Category: Science Authors: Wilder-Smith, A., Hombach, J., Cravioto, A. Tags: letters Source Type: news

Study of intestinal bacteria of insects may reveal strategies for combatting them
(Funda ç ã o de Amparo à Pesquisa do Estado de S ã o Paulo) Intestinal microbiota of mosquito that transmits dengue and of bugs resistant to insecticides is the focus of studies developed at the Universit é Claude Bernard Lyon1 and presented at FAPESP Week France. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - November 27, 2019 Category: Biology Source Type: news

Simulating amino acid starvation may improve dengue vaccines
(Cornell University) In a new paper in Science Signaling, researchers at the University of Hyderabad in India and the Cornell University College of Veterinary Medicine show that a plant-based compound called halofuginone improves the immune response to a potential vaccine against dengue virus. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 26, 2019 Category: International Medicine & Public Health Source Type: news

Structurally designed DNA star creates ultra-sensitive test for dengue virus
(Rensselaer Polytechnic Institute) By folding snippets of DNA into the shape of a five-pointed star using structural DNA nanotechnology, researchers have created a trap that captures Dengue virus as it floats in the bloodstream. Published in Nature Chemistry, the trap is the most sensitive test for the mosquito-borne diseases yet devised, and the technique could be expanded to other viruses and adapted to kill the viruses it snares. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - November 25, 2019 Category: Infectious Diseases Source Type: news

Longer-term data fail to clear concern over Takeda's dengue vaccine
An additional six months of data from a late-stage trial of Takeda Pharmaceutical Co's experimental dengue vaccine again showed it failed to protect against one of the four types of the virus in an important patient group, researchers said on Saturday. (Source: Reuters: Health)
Source: Reuters: Health - November 23, 2019 Category: Consumer Health News Tags: healthNews Source Type: news

Bacteria Could Be Weapon Against Mosquito-Borne Dengue
The strategy resulted in a 76% decrease in dengue transmission in a community in Indonesia that has frequent dengue outbreaks. Similar reductions were seen in an urban area near Rio de Janeiro, and around Nha Trang, Vietnam. (Source: WebMD Health)
Source: WebMD Health - November 22, 2019 Category: Consumer Health News Source Type: news

Dengue Cases Drop After Bacteria-Infected Mosquitoes Released
Aedes aegypti infected with Wolbachia —which inhibit transmission of the dengue virus from insect to human—were deployed in Indonesia, Vietnam, Brazil, and Australia. (Source: The Scientist)
Source: The Scientist - November 22, 2019 Category: Science Tags: News & Opinion Source Type: news

Sudan: 'Unprecedented' Malaria, Dengue Epidemics in North Darfur
[Radio Dabanga] El Fasher -On Wednesday, North Darfur health authorities reported that 23 people died of malaria and four of dengue fever during the past week, stressing that the state has never seen such epidemics before. The federal Minister of Health announced an emergency plan to contain the spread of diseases in the region. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - November 22, 2019 Category: African Health Source Type: news

Bacteria Could Be Weapon Against Mosquito-Borne Dengue
FRIDAY, Nov. 22, 2019 -- Lab-altered mosquitoes have made a big dent in the spread of dengue fever, researchers report. How? Australian scientists released mosquitoes carrying a bacteria that prevents transmission of the dengue virus. The strategy... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - November 22, 2019 Category: General Medicine Source Type: news

Bacterial allies make dengue fever cases dive
Scientists infected mosquitoes with Wolbachia bacteria to make it harder for them to spread disease. (Source: BBC News | Health | UK Edition)
Source: BBC News | Health | UK Edition - November 22, 2019 Category: Consumer Health News Source Type: news