TWiV 1105: All the T and B in China
TWiV reviews influenza H5N1 in North American cows and in birds throughout New York City, polio health emergency extended, ChatGPT to control vaccine hesitancy, increasing viral hepatitis worldwide, dengue public health alert in Puerto Rico, cherry trees drowning in Washington DC, death of iron lung Paul, origin and dispersal history of hepatitis B virus in Eastern Eurasia, and antibody-independent protection against heterologous SARS-CoV-2 challenge. Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Kathy Spindler Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links fo...
Source: This Week in Virology - MP3 Edition - April 14, 2024 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 1093: Reservoir bats and jumbo phage
TWiV discusses effectiveness of this season’s flu vaccine, efficacy of Pfizer RSV vaccine, nOPV2 in the US, dengue in Peru, measles in Michigan and Indiana, how coordinated inflammatory responses dictate control of Marburg virus by reservoir bats, and tRNA acquisition in phages driven by degradation of host translational machinery. Hosts: Vincent Racaniello, Rich Condit, Kathy Spindler, Brianne Barker, and Jolene Ramsey Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode MicrobeTV Discord Server MicrobeTV store at Cafepress Become a member of ASV (asv...
Source: This Week in Virology - MP3 Edition - March 3, 2024 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 1087: Should old infections be forgot
TWiV reviews rhinovirus complications in infants, a new influenza antiviral drug, Oropouche fever in Brazil, measles in Maryland and Ohio, effect of eliminating non-medical vaccine exemptions in NY, foot-and-mouth disease in Europe, severe primary and secondary dengue infections, and therapeutic mitigation of measles-like immune amnesia and exacerbated disease after prior respiratory virus infections. Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit, and Angela Mingarelli Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode MicrobeTV Discord Server...
Source: This Week in Virology - MP3 Edition - February 11, 2024 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 1079: Rock of phages
TWiV reveals how viruses participate in the organomineralization of travertines, and how neutralizing antibodies evolve to exploit vulnerable sites in the hepatitis C virus envelope glycoprotein E2 and mediate clearance of infection. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, Kathy Spindler, and Brianne Barker Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode MicrobeTV Discord Server MicrobeTV store at Cafepress Become a member of ASV (asv.org) Research assistant position in Rosenfeld Lab CBER/FDA (pdf) The New City by Dick...
Source: This Week in Virology - MP3 Edition - January 13, 2024 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

A new hydrogel can be directly injected into muscle to help it regenerate
In this episode:00:46 An injectable gel for healing musclesSevere muscle injury can be debilitating, with long recuperation periods. Now, researchers have developed a material that can be directly injected into injured muscle, helping to stimulate and heal damaged tissue. The team showed this approach could rapidly restore walking ability in severely injured rats and regenerate muscles within four weeks. They hope that this solution could one day help humans with similar injuries, and overcome some of the limitations of current recuperation strategies.Research article: Jin et al.News and Views: Hydrogel implant rehabilitat...
Source: Nature Podcast - November 1, 2023 Category: Science Authors: Springer Nature Limited Source Type: podcasts

TWiV 1036: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin discusses Florida local transmission of dengue cases reported in Broward and Miami-Dade counties, infants admitted to US intensive care units for RSV infection during the 2022 seasonal peak, long-term risk of death and readmission after hospital admission with COVID-19 among older adults, safety profile and clinical and virological outcomes of Nirmatrelvir-Ritonavir treatment in patients with advanced chronic kidney disease and COVID-19, Fluvoxamine vs placebo for outpatients with symptomatic COVID-19, the effect of corticosteroids, antibiotics, and anticoagulants on the developme...
Source: This Week in Virology - MP3 Edition - August 19, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 1033: Freediving with nanobodies and interferon
TWiV notes the passing of Harald zur Hausen, dengue breaking records in the Americas, inhibition of SARS-CoV-2 infection and inflammation by modulation of type I IFN, and an armed nanobody that protects mice against influenza A and B disease. Hosts: Vincent Racaniello, Kathy Spindler, and Angela Mingarelli Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode MicrobeTV Discord Server MicrobeTV store at Cafepress Position in Rosenfeld Laboratory (pdf) Paul and the Mosquitos (pdf, English) Other childrens books (SMVIROLOGIA) Dengue breaking records in Amer...
Source: This Week in Virology - MP3 Edition - August 6, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 965: Asking Esper Kallas for some I.D.
Brazilian infectious diseases physician Esper Kallas returns to TWiV to discuss the state of viral diseases in his country, including those cause by Zika, dengue, and yellow fever viruses, MPOX, and SARS-CoV-2. Hosts: Vincent Racaniello and Alan Dove Guest: Esper Kallas Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support MicrobeTV with a Spike t-shirt (Vaccinated.us) with promo code MicrobeTV International Scientific Coordinator Position (agajewski at icsnicaragua.org for more info) Viral kinetics in sylvatic yellow fever (J Inf Dis) Safety an...
Source: This Week in Virology - MP3 Edition - December 18, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 882: Elispot on about T cells and lipids
Vincent and Brianne review the need to better understand T cell responses to SARS-CoV-2 infection to better inform public health decisions, and how IL-1 and IL-1ra are important regulators of the inflammatory response to RNA vaccines. Hosts: Vincent Racaniello and Brianne Barker Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Understanding T cell responses during COVID-19 (Science Immunol) IL-1 and IL-1ra are keys to inflammation after RNA vaccination (Nature Immunol) Letters read on TWiV 882 Timestamps by Jolene. Thanks! Weekly Picks Brianne – Covid r...
Source: This Week in Virology - MP3 Edition - March 31, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 847: On Dasher, on Dancer, on Corona and Lassa
For the final episode of 2021, TWiV reviews an experimental infectious attenuated Lassa fever vaccine based on a codon-deoptimized glycoprotein gene, and SARS-CoV-2 infection of free-ranging white-tailed deer. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Kathy Spindler, and Brianne Barker Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Codon-deoptimized Lassa fever vaccine (mBio) Attenuation of dengue virus by codon deoptimization (TWiV 351) Codon deoptimization of poliovirus and RS virus (TWiV 740) Codon deoptimization of DNA viruses (TWiV 362 lett...
Source: This Week in Virology - MP3 Edition - January 2, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 776: Yes! We have no pangolins
TWiV reviews an analysis of animal sales from Wuhan wet markets before the COVID-19 pandemic, control of dengue by release of Wolbachia-infected mosquitoes, and fatal dengue acquired in Florida. Hosts: Vincent Racaniello, Alan Dove, and Brianne Barker Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Animal sales from Wuhan markets before COVID-19 (Sci Rep) Dengue control by Wolbachia-infected mosquitoes (NEJM) Fatal dengue in Florida (NEJM) Letters read on TWiV 776 Timestamps by Jolene. Thanks! Weekly Picks Brianne – You Know You’ve Worked Too Long in a Lab W...
Source: This Week in Virology - MP3 Edition - July 4, 2021 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 725: Eva Harris and Janet Smith clip flavivirus wings
Eva Harris and Janet Smith join TWiV to discuss how an antibody against dengue virus NS1 protein blocks endothelial dysfunction and the potential of treating infections by multiple flaviviruses. Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Kathy Spindler Guest: Eva Harris and Janet Smith Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Eva Harris on TWiV 228 Zika virus in Nicaragua (virology blog) How an antibody block NS1-mediated endothelial dysfunction (Science) Broadly protective antibody against NS1 (Science) Letters read on TWiV 725 Timestamps by ...
Source: This Week in Virology - MP3 Edition - February 28, 2021 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

A new way to cool computer chips — from within
Keeping electronics from overheating, and how to include minority populations in genetic analyses.In this episode:00:46 Cool computersKeeping components cool is a major hurdle when it comes to increasing electronic power. This week, we find out about a new way to integrate tiny microfluidic channels directly into circuits, to help keep them cool. Research Article: van Erp et al.06:57 CoronapodBy comparing coronavirus genomes taken from people around the world, researchers are getting an idea of how SARS-CoV-2 is changing as it spreads. We discuss a particular genetic mutation that rapidly became dominant early in the pande...
Source: Nature Podcast - September 9, 2020 Category: Science Authors: Springer Nature Limited Source Type: podcasts

A new way to cool computer chips — from within
Keeping electronics from overheating, and how to include minority populations in genetic analyses.In this episode:00:46 Cool computersKeeping components cool is a major hurdle when it comes to increasing electronic power. This week, we find out about a new way to integrate tiny microfluidic channels directly into circuits, to help keep them cool. Research Article: van Erp et al.06:57 CoronapodBy comparing coronavirus genomes taken from people around the world, researchers are getting an idea of how SARS-CoV-2 is changing as it spreads. We discuss a particular genetic mutation that rapidly became dominant early in the pande...
Source: Nature Podcast - September 9, 2020 Category: Science Authors: Springer Nature Limited Source Type: podcasts