Clinical and laboratory profile of Expanded Dengue Syndrome: experience of 2019 outbreak from Dhaka, Bangladesh
CONCLUSION: In the year 2019, an unusual rise in EDS cases with about 15.4% fatalities were observed in this study. Hepatitis was the most common presentation and cause of death. Here, we report the first ARDS case encountered in Bangladesh. Despite the multifaceted presentation of EDS, indiscriminate use of antibiotics and steroid was minimal. Early recognition of multifarious features of EDS is important for choosing the targeted treatment option which can avert many deaths. The results of this study underline the necessity for more in-depth research into the risk factors that are contributing to mortality in EDS cases.P...
Source: Journal of Vector Borne Diseases - April 22, 2024 Category: Infectious Diseases Authors: Zazeba Hossain Forhad U Chowdhury Mohammad A Bari Sudip R Deb Ujjwal Mallik Sakib Aman Mohammad A Haque Syeda S Ahmed Waild Mohammad Afsan Bulbul Md Arman Hossain Murada Alam Muhammad K Islam Umma Salma Md Mujibur Rahman Fazle R Chowdhury Source Type: research

Circulating serotypes and genotypes of dengue virus in North India: An observational study
CONCLUSION: DENV-1, DENV-2 and DENV-3 were found to be in circulation in North India. Predominant serotype/genotype changed at times, but not at regular intervals.PMID:38648413 | DOI:10.4103/0972-9062.392258 (Source: Journal of Vector Borne Diseases)
Source: Journal of Vector Borne Diseases - April 22, 2024 Category: Infectious Diseases Authors: Om Prakash Anil Kumar Verma Asutosh Paliwal Faisal Abbas Ashish Kumar Srivastava Vivek Kumar Mishra Shruti Radera Amita Jain Source Type: research

Assessment of larval and pupal indices of dengue mosquito vectors in a North-Eastern state of Tripura, India
CONCLUSION: The present study identified Ae. albopictus as a potential vector of dengue in Tripura. The study gave important insights on the preferred larval habitats and provides information on the indication of displacement of Ae. albopictus from rural to urban and semi-urban areas. However, longitudinal studies for longer time frame are necessary for any conclusive remarks.PMID:38648411 | DOI:10.4103/0972-9062.392268 (Source: Journal of Vector Borne Diseases)
Source: Journal of Vector Borne Diseases - April 22, 2024 Category: Infectious Diseases Authors: Siraj Ahmed Khan Smita Bordoloi Anisha Shah Subrata Baidya Source Type: research

Seroprevalence study of dengue-malaria coinfection in an East-Cameroonian public hospital: A comparison between malarial and non-malarial groups
CONCLUSION: In the study, coinfected patients were found to be more vulnerable to dengue, emphasizing the importance of epidemiological surveillance.PMID:38648408 | DOI:10.4103/0972-9062.392260 (Source: Journal of Vector Borne Diseases)
Source: Journal of Vector Borne Diseases - April 22, 2024 Category: Infectious Diseases Authors: Elodie Ayangma Ndeme Borris Rosnay Galani Tietcheu Sylvie Agokeng Demanou Dieudonne Pascal Chuisseu Djamen Nicolas Njintang Yanou Source Type: research

Isolation and molecular detection of dengue and chikungunya virus from field-collected adult mosquitoes in Kelantan, Malaysia
CONCLUSION: The presence of DENV and the main vectors of arboviruses in Kelantan are pertinent indicators of the need to improve vector controls to reduce arbovirus infections among people in the localities.PMID:38648407 | DOI:10.4103/0972-9062.392269 (Source: Journal of Vector Borne Diseases)
Source: Journal of Vector Borne Diseases - April 22, 2024 Category: Infectious Diseases Authors: Tuan Nur A Mat Jusoh Izhan S Jaafar Rafidah H Shueb Source Type: research

MBORS: Mosquito vector Biocontrol Ontology and Recommendation System
CONCLUSION: The MVAont predicts harmless biocontrol agents which help to diminish the rate of vector-borne diseases. On the other hand, the MosqVecRS system raises awareness of vectors and vector-borne diseases by recommending suitable biocontrol agents to the vector control community and researchers.PMID:38648406 | DOI:10.4103/0972-9062.383640 (Source: Journal of Vector Borne Diseases)
Source: Journal of Vector Borne Diseases - April 22, 2024 Category: Infectious Diseases Authors: G Jeyakodi P Shanthi Bala O T Sruthi K Swathi Source Type: research

Dengue virus pathogenesis and host molecular machineries
Dengue viruses (DENV) are positive-stranded RNA viruses belonging to the Flaviviridae family. DENV is the causative agent of dengue, the most rapidly spreading viral disease transmitted by mosquitoes. Each yea... (Source: Journal of Biomedical Science)
Source: Journal of Biomedical Science - April 22, 2024 Category: Biomedical Science Authors: Saumya Sinha, Kinjal Singh, Y. S. Ravi Kumar, Riya Roy, Sushant Phadnis, Varsha Meena, Sankar Bhattacharyya and Bhupendra Verma Tags: Review Source Type: research

Dengue encephalitis: A rare manifestation of dengue fever
J Vector Borne Dis. 2024 Apr 18. doi: 10.4103/JVBD.JVBD_189_23. Online ahead of print.ABSTRACTDengue fever, caused by the dengue virus transmitted by mosquitoes, usually manifests as flu-like symptoms and is a prevalent tropical illness. However, there are rare cases where the infection takes an unusual course, resulting in severe complications like dengue encephalitis. This case report delineates an occurrence of dengue encephalitis in a patient from Sri Lanka. This work provides insights into the clinical presentation, diagnostic difficulties, and treatment approaches linked to this uncommon manifestation of dengue fever...
Source: Journal of Vector Borne Diseases - April 18, 2024 Category: Infectious Diseases Authors: Hewa Babarandage Chathurika Harshani Denagama Vitharanage Rishan Geeth Ruwan Gamage Don Diluk Chathuranga Dedunu C U Dias Weligamagea Janaki I Abeynayake Source Type: research

Dengue dynamics: Prognostic and disease monitoring through molecular and serological profiling of clinical isolates
CONCLUSION: Our laboratory effectively standardized an RT-PCR-based approach for molecular identification of dengue virus in clinical specimens. This adaptive technique which used numerous primer sets displayed good specificity and sensitivity in serotype detection. The technology provides for quick and reliable identification of dengue virus infections, allowing for targeted treatment and preventative actions for successful disease management in highly populated regions.PMID:38634367 | DOI:10.4103/JVBD.JVBD_202_23 (Source: Journal of Vector Borne Diseases)
Source: Journal of Vector Borne Diseases - April 18, 2024 Category: Infectious Diseases Authors: Vikas Tiwari Mohd Afzal Abhishek Sharma Jaishree Tiwari Source Type: research

Shifting spatial, temporal and demographic patterns of dengue incidence and associated meteorological factors in Jazan Region of Saudi Arabia from 2015-2020
CONCLUSION: Enhanced surveillance, outbreak forecasting, targeted control activities, and integrated prevention policies grounded in continuous evidence assessment can effectively address endemic dengue transmission in Jazan. This study provides key insights to optimize data-driven decision-making for dengue control in Saudi Arabia.PMID:38634364 | DOI:10.4103/JVBD.JVBD_15_24 (Source: Journal of Vector Borne Diseases)
Source: Journal of Vector Borne Diseases - April 18, 2024 Category: Infectious Diseases Authors: Ahmad Y Alqassim Mohammed Badedi Mohammed A Muaddi Abdullah A Alharbi Mohammad A Jareebi Anwar M Makeen Maged El-Setouhy Osama B Albasheer Abdullah Sabai Ahmed Sahly Source Type: research

Dengue encephalitis: A rare manifestation of dengue fever
J Vector Borne Dis. 2024 Apr 18. doi: 10.4103/JVBD.JVBD_189_23. Online ahead of print.ABSTRACTDengue fever, caused by the dengue virus transmitted by mosquitoes, usually manifests as flu-like symptoms and is a prevalent tropical illness. However, there are rare cases where the infection takes an unusual course, resulting in severe complications like dengue encephalitis. This case report delineates an occurrence of dengue encephalitis in a patient from Sri Lanka. This work provides insights into the clinical presentation, diagnostic difficulties, and treatment approaches linked to this uncommon manifestation of dengue fever...
Source: Journal of Vector Borne Diseases - April 18, 2024 Category: Infectious Diseases Authors: Hewa Babarandage Chathurika Harshani Denagama Vitharanage Rishan Geeth Ruwan Gamage Don Diluk Chathuranga Dedunu C U Dias Weligamagea Janaki I Abeynayake Source Type: research

Dengue dynamics: Prognostic and disease monitoring through molecular and serological profiling of clinical isolates
CONCLUSION: Our laboratory effectively standardized an RT-PCR-based approach for molecular identification of dengue virus in clinical specimens. This adaptive technique which used numerous primer sets displayed good specificity and sensitivity in serotype detection. The technology provides for quick and reliable identification of dengue virus infections, allowing for targeted treatment and preventative actions for successful disease management in highly populated regions.PMID:38634367 | DOI:10.4103/JVBD.JVBD_202_23 (Source: Journal of Vector Borne Diseases)
Source: Journal of Vector Borne Diseases - April 18, 2024 Category: Infectious Diseases Authors: Vikas Tiwari Mohd Afzal Abhishek Sharma Jaishree Tiwari Source Type: research

Shifting spatial, temporal and demographic patterns of dengue incidence and associated meteorological factors in Jazan Region of Saudi Arabia from 2015-2020
CONCLUSION: Enhanced surveillance, outbreak forecasting, targeted control activities, and integrated prevention policies grounded in continuous evidence assessment can effectively address endemic dengue transmission in Jazan. This study provides key insights to optimize data-driven decision-making for dengue control in Saudi Arabia.PMID:38634364 | DOI:10.4103/JVBD.JVBD_15_24 (Source: Journal of Vector Borne Diseases)
Source: Journal of Vector Borne Diseases - April 18, 2024 Category: Infectious Diseases Authors: Ahmad Y Alqassim Mohammed Badedi Mohammed A Muaddi Abdullah A Alharbi Mohammad A Jareebi Anwar M Makeen Maged El-Setouhy Osama B Albasheer Abdullah Sabai Ahmed Sahly Source Type: research

Viruses, Vol. 16, Pages 630: Identification of Bacteria and Viruses Associated with Patients with Acute Febrile Illness in Khon Kaen Province, Thailand
Piyada Linsuwanon The majority of cases of undifferentiated acute febrile illness (AFI) in the tropics have an undefined etiology. In Thailand, AFI accounts for two-thirds of illnesses reported to the Ministry of Public Health. To characterize the bacterial and viral causes of these AFIs, we conducted molecular pathogen screening and serological analyses in patients who sought treatment in Chum Phae Hospital, Khon Kaen province, during the period from 2015 to 2016. Through integrated approaches, we successfully identified the etiology in 25.5% of cases, with dengue virus infection being the most common cause, noted i...
Source: Viruses - April 18, 2024 Category: Virology Authors: Rungrat Jitvaropas Vorthon Sawaswong Yong Poovorawan Nutthanun Auysawasdi Viboonsak Vuthitanachot Sirima Wongwairot Wuttikon Rodkvamtook Erica Lindroth Sunchai Payungporn Piyada Linsuwanon Tags: Article Source Type: research

Design, development, and validation of multi-epitope proteins for serological diagnosis of Zika virus infections and discrimination from dengue virus seropositivity
by Samille Henriques Pereira, Mateus S á Magalhães Serafim, Thaís de Fátima Silva Moraes, Nathalia Zini, Jônatas Santos Abrahão, Maurício Lacerda Nogueira, Jordana Grazziela Alves Coelho dos Reis, Flávia Fonseca Bagno, Flávio Guimarães da Fonseca Zika virus (ZIKV), an arbovirus from theFlaviviridae family, is the causative agent of Zika fever, a mild and frequent oligosymptomatic disease in humans. Nonetheless, on rare occasions, ZIKV infection can be associated with Guillain-Barr é Syndrome (GBS), and severe congenital complications, such as microcephaly. The oligosymptomatic disease, however, presents symptom...
Source: PLoS Neglected Tropical Diseases - April 18, 2024 Category: Tropical Medicine Authors: Samille Henriques Pereira Source Type: research