TWiV 981: Tastes like chikungunya
TWiV explains the recent meeting of the National Science Advisory Board for Biosecurity (NSABB) where stricter guidelines for research involving human, animal, and plant pathogens were considered, and how the consumption of viruses by small protists returns energy to food chains. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Kathy Spindler Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode •Research assistant position at FDA (pdf) •Register for ASV 2023 •MicrobeTV Discord Server •NSABB proposed oversight framework (pdf) ...
Source: This Week in Virology - MP3 Edition - February 5, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 908: Clinical update with Dr. Daniel Griffin
In his weekly clinical update Dr. Griffin discusses prevalence and clinical outcomes of respiratory syncytial virus versus influenza virus in adults hospitalized with acute respiratory Illness, reconsideration of antinucleocapsid IgG antibody as a marker of SARS-CoV-2 infection postvaccination for mild COVID-19 patients, assessment of COVID-19 as the underlying cause of death among children and young people aged 0 to 19 years in the US, information for persons who are immunocompromised regarding prevention and treatment of SARS-CoV-2 Infection in the context of currently circulating Omicron sublineages, association of c...
Source: This Week in Virology - MP3 Edition - February 4, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV Special: One COVID vaccine for them all with Paul Offit
Paul Offit returns to TWiV to unpack the recent FDA Advisory Panel on COVID vaccines, with discussions on giving everyone the same bivalent vaccine, simplifying the immunization schedule, and how to know when the vaccine should be updated. Hosts: Vincent Racaniello and Rich Condit Guest: Paul Offit Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode FDA briefing document (pdf) Effectiveness of bivalent booster against severe infection (NEJM) Timestamps by Jolene. Thanks! Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@micr...
Source: This Week in Virology - MP3 Edition - February 3, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 979: Flushing out the viroids
TWiV gives an update on poliovirus in wastewater, and reveals a vast world of viroids that infect a wide range of host species in diverse ecosystems. Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Kathy Spindler Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode •Research assistant position at FDA (pdf) •Register for ASV 2023 •MicrobeTV Discord Server •Nick Muzyczka passes •CDC planning wastewater testing for polio (CDC) •Wastewater testing for poliovirus (MMWR) •NY state poliovirus wastewater surveillance (NYSDOH) •CDC wa...
Source: This Week in Virology - MP3 Edition - January 29, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 978: Clinical update with Dr. Daniel Griffin
In his weekly clinical update Dr. Griffin discusses co-detections of other respiratory viruses among children hospitalized with COVID-19, preprint review should form part of PhD programs and postdoc training, early and increased Influenza activity among children, COVID-19 vaccines versus pediatric hospitalization, SARS-CoV-2 variant-related abnormalities detected by prenatal MRI, protective effectiveness of previous SARS-CoV-2 infection and hybrid immunity against the Omicron variant and severe disease, protective effectiveness of previous SARS-CoV-2 infection and hybrid immunity against the omicron variant and severe dis...
Source: This Week in Virology - MP3 Edition - January 28, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 977: Ageing is infectious
TWiV covers a study of SARS-CoV-2 persistence at multiple sites in the human body, and the role of endogenous retroviruses in ageing and senescence. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Brianne Barker, and Angela Mingarelli Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode •Research assistant position at FDA (pdf) •Register for ASV 2023 •MicrobeTV Discord Server •Persistence of SARS-CoV-2 (Nature) •Endogenous retroviruses and senescence (Cell) •Timestamps by Jolene. Thanks! Weekly Picks Dickson – Baritone Saxoph...
Source: This Week in Virology - MP3 Edition - January 22, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 976: Clinical update with Dr. Daniel Griffin
In his weekly clinical update Dr. Griffin discusses China reporting almost 60,000 Covid-related deaths after abrupt shift in policy, detection of SARS-CoV-2 IgA and IgG in human milk and breastfeeding infant stool 6 months after maternal COVID-19 vaccination, effect of Fluvoxamine vs placebo on time to sustained recovery in outpatients with mild to moderate COVID-19, hyperimmune globulin for severely immunocompromised patients hospitalized with COVID-19, long COVID outcomes at one year after mild SARS-CoV-2 infection, long COVID: major findings, mechanisms and recommendations, a systematic review of trials currently inves...
Source: This Week in Virology - MP3 Edition - January 21, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 975: Crossing the Ts with Daniela Weiskopf
Daniela joins TWiV to discuss her career and her research on T cells, their role in infection with SARS-CoV-2, T cell epitopes and why a variant that evades T cell immunity is not likely to emerge. Hosts: Vincent Racaniello, Alan Dove, and Brianne Barker Guest: Daniela Weiskopf Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode •Research assistant position at FDA (pdf) •Register for ASV 2023 •Cross reactive T cells to SARS-CoV-2 (Science) •SARS-CoV-2 exposure history and T cell response (Cell Rep Med) •Spike T cells cross- recognize Omicron (Natur...
Source: This Week in Virology - MP3 Edition - January 15, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 974: Clinical update with Dr. Daniel Griffin
In his weekly clinical update Dr. Griffin discusses poliovirus returns to New York wastewater, COVID-19 is more widespread in animals than we thought, increasing ventilation reduces SARS-CoV-2 airborne transmission in schools, the use of carbon dioxide monitoring to assess ventilation at a national infectious diseases conference, effectiveness of the bivalent mRNA vaccine in preventing severe COVID-19 outcomes, 7-month duration of SARS-CoV-2 mucosal immunoglobulin-A responses and protection, and long COVID outcomes at one year after mild SARS-CoV-2 infection. Subscribe (free): Apple Podcasts, Google Podcasts, RSS...
Source: This Week in Virology - MP3 Edition - January 14, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 973: Crouching virus, hidden triggers with Felicia Goodrum
Felicia joins TWiV to discuss her career and her research on human cytomegalovirus, which infects most of us for our entire lives yet mainly causes disease in the immunosuppressed. Hosts: Vincent Racaniello, Alan Dove, and Brianne Barker Guest: Felicia Goodrum Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode •Research assistant position at FDA (pdf) •The loss of binary (Curr Clin Micro Rep) •Virology in Peril (mBio) •Letters read on TWiV 973 •Timestamps by Jolene. Thanks! Weekly Picks Brianne – “Leukocyte” immunology video parody ...
Source: This Week in Virology - MP3 Edition - January 8, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 972: Clinical update with Dr. Daniel Griffin
In his weekly clinical update Dr. Griffin discusses the infectiousness of SARS-CoV-2 breakthrough infections and reinfections during the Omicron wave, virological characteristics of the SARS-CoV-2 XBB variant derived from recombination of two Omicron subvariants, antibody evasion properties of rising SARS-CoV-2 BQ and XBB subvariants, comparative effectiveness of third doses of mRNA-based COVID-19 vaccines in US veterans, time to negative PCR conversion among high-risk patients with mild-to-moderate Omicron BA.1 and BA.2 COVID-19 treated by Sotrovimab or Nirmatrelvir, COVID drug Paxlovid was hailed as a game-changer,...
Source: This Week in Virology - MP3 Edition - January 7, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 971: Another year is viral
In the first epitope of 2023, TWiV reviews our coverage of virology in 2022, including favorite story arcs, episodes, show titles, and much more. Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit, Kathy Spindler, and Brianne Barker Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Our favorite 2022 virology stories: •Vincent: Paul Offit on bivalent boosters (TWiV 917, 942, Special) •Dickson: Interviews with Paul Offit and Andy Slavitt •Rich: TWiV 948: Breathless with David Quammen •Kathy: TWiV 915: Mouse mouth to mouse mom •Bri...
Source: This Week in Virology - MP3 Edition - January 1, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 970: Clinical update with Dr. Daniel Griffin
In his weekly clinical update Dr. Griffin discusses modelling the adjustment of COVID-19 response and exit from dynamic zero-COVID in China, canine real-time detection of SARS-CoV-2 infections in the context of a mass screening event, two masks can be worse than one: N95 respirator failure caused by an overlying face mask, airflow patterns in double-occupancy patient rooms may contribute to roommate-to-roommate transmission of severe SARS-CoV-2, clinical validation of a novel T-Cell receptor sequencing assay for identification of recent or prior SARS-CoV-2 infection, antibody-dependent cellular cytotoxicity against SARS-...
Source: This Week in Virology - MP3 Edition - December 31, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 969: Carl Zimmer on COVID-19
Carl Zimmer visits the Incubator to record a wide-ranging conversation about COVID-19, including origins, vaccines, public health responses, and impact on society. Host: Vincent Racaniello Guest: Carl Zimmer Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv (Source: This Week in Virology - MP3 Edition)
Source: This Week in Virology - MP3 Edition - December 28, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 968: A spillover waiting in the wings
TWiV reviews eukaryotic viruses recovered from ancient permafrost, a mistake made by scientists on Omicron origins, and close relatives of MERS-CoV from bats that bind ACE2 for entry into cells. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Brianne Barker Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support MicrobeTV with a Spike t-shirt (Vaccinated.us) with promo code MicrobeTV Positions with the Mosquito and Vector Control Division in Harris County Public Health (one and two) Ancient eukaryotic viruses from permaf...
Source: This Week in Virology - MP3 Edition - December 25, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts