TWiV 473: Assessing a risk and infecting you twice
The Fellowship of the Virus discuss enhancement of dengue disease in humans: the contribution of antibody concentration and increased binding to Fc receptors. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Kathy Spindler Become a patron of TWiV! Links for this episode ASV 2018: asv.org, asv2018.umd.edu Support Microbe.tv NEIDL is approved NIH lifts GOF moratorium (Science) Blackburn steps down as head of Salk Institute (SD Union Trib) ADE of dengue disease in humans (Science) Commentary on ADE of dengue disease (Science) ADE of dengue disease and antibody binding to Fc (Science) Letters re...
Source: This Week in Virology - MP3 Edition - December 24, 2017 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
TWiV 471: Songs of innocence and experience
The TWiVerinos discuss restriction of dengue virus vaccine by Sanofi, and data which suggest that Dengvaxia causes enhanced disease in previously uninfected recipients. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Kathy Spindler Become a patron of TWiV! Links for this episode ASV 2018: asv.org, asv2018.umd.edu Sanofi update on Dengvaxia Trouble for dengue vaccine (Reuters) Sanofi restricts dengue vaccine (CIDRAP) Dengvaxia enhances disease (Vaccine) Interview with Jeff Almond Dengue vaccine on TWiV 319, TWiV 370, TWIV 384 Image credit Letters read on TWiV 471 Weekly Science Picks Kat...
Source: This Week in Virology - MP3 Edition - December 10, 2017 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
TWiV 458: Saliva of the fittest
The TWiVians present an imported case of yellow fever in New York City, and explain how a dengue virus subgenomic RNA disrupts immunity in mosquito salivary glands to increase virus replication. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Kathy Spindler Become a patron of TWiV! Links for this episode ASM Conference on Viral Manipulation of Nuclear Processes Roger W. Hendrix, 74 (Pittsburgh Post-Gazette) Roger Hendrix video on TWiV #135 Yellow fever in traveler returning from Peru (MMWR) Dengue subgenomic RNA in mosquito salivary gland (PLoS Path) Image credit Letters read on TWiV 458 Thi...
Source: This Week in Virology - MP3 Edition - September 9, 2017 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
TWiV 456: Be careful of canons
Brianne joins the TWiVMasters to explain how mutations in genes encoding RNA polymerase III predispose children to severe varicella, and detection of an RNA virus by a DNA sensor. Hosts: Vincent Racaniello and Rich Condit Guest: Brianne Barker Become a patron of TWiV! Links for this episode RNA pol III mutations underlie severe varicella (J Clin Inves) Dengue virus activates cGAS by release of mitochondrial DNA (Sci Rep) Dengue virus NS2B protein targets cGAS for degradation (Nat Micr) Image credit Letters read on TWiV 456 This episode is brought to you by the Defense Threat Reduction Agency. Part of the U.S. Departm...
Source: This Week in Virology - MP3 Edition - August 26, 2017 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
TWiV 454: FGCU, Zika
Sharon and Scott return to TWiV for a Zika virus update, including their work on viral evolution and spread, and whether pre-existing immunity to dengue virus enhances pathogenesis. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, and Kathy Spindler Guests: Sharon Isern and Scott Michael Become a patron of TWiV! Links for this episode Hurricane Zika (TWiV 410) 454 Corporation (Wikipedia) Regional Zika update, Americas (PAHO, WHO) Zika virus serum bank (pdf) Zika virus evolution and spread in the Americas (Nature) Multiple introductions of Zika virus in US (Nature) Inhibition of Zika Virus Replication by ...
Source: This Week in Virology - MP3 Edition - August 13, 2017 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
TWiV 420: Orthogonal vectors
Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Kathy SpindlerThe TWiV gurus describe how to use an orthogonal translation system to produce infectious but replication-incompetent influenza vaccines. Become a patron of TWiV!Links for this episodeRegister for ASV 2017Local Zika virus transmission in TexasTexaszika.orgLocal dengue virus transmission in Texas (EID)No more Zika virus transmission in Florida (FL DOH)Dengue virus antibodies enhance Zika virus infection (Clin Trans Imm)Infectious, replication incompetent influenza virus vaccine (Science)Pyrrolysl-tRNA synth...
Source: This Week in Virology - MP3 Edition - December 18, 2016 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
Podcast: When we pay attention to plane crashes, releasing modified mosquitoes, and bacteria that live off radiation
This week, we chat about some of our favorite stories -- including a new bacterial model for alien life that feeds on cosmic rays, tracking extinct “bear dogs” to Texas, and when we stop caring about plane crashes -- with Science’s Online News Editor David Grimm. Plus, Alexa Billow talks to Staff Writer Kelly Servick about her feature story on the releasing modified mosquitoes in Brazil to combat diseases like Zika, dengue, and chikunguny a. Her story is part of a package on mosquito control. Listen to previous podcasts [Image: © Alex Wild; Music: Jeffrey Cook] (Source: Science Magazine Podcast)
Source: Science Magazine Podcast - October 13, 2016 Category: Science Authors: Science Tags: Scientific Community Source Type: podcasts
Podcast: When we pay attention to plane crashes, releasing modified mosquitoes, and bacteria that live off radiation
This week, we chat about some of our favorite stories -- including a new bacterial model for alien life that feeds on cosmic rays, tracking extinct “bear dogs” to Texas, and when we stop caring about plane crashes -- with Science’s Online News Editor David Grimm. Plus, Alexa Billow talks to Staff Writer Kelly Servick about her feature story on the releasing modified mosquitoes in Brazil to combat diseases like Zika, dengue, and chikungun ya. Her story is part of a package on mosquito control. Listen to previous podcasts [Image: © Alex Wild; Music: Jeffrey Cook] (Source: Science Magazine Podcast)
Source: Science Magazine Podcast - October 13, 2016 Category: Science Authors: Science Tags: Scientific Community Source Type: podcasts
Podcast: When we pay attention to plane crashes, releasing modified mosquitoes, and bacteria that live off radiation
This week, we chat about some of our favorite stories -- including a new bacterial model for alien life that feeds on cosmic rays, tracking extinct “bear dogs” to Texas, and when we stop caring about plane crashes -- with Science’s Online News Editor David Grimm. Plus, Alexa Billow talks to Staff Writer Kelly Servick about her feature story on the releasing modified mosquitoes in Brazil to combat diseases like Zika, dengue, and chikungunya. Her story is part of a package on mosquito control. Listen to previous podcasts [Image: © Alex Wild; Music: Jeffrey Cook] (Source: Science Magazine Podcast)
Source: Science Magazine Podcast - October 13, 2016 Category: Science Authors: Science Magazine Source Type: podcasts
TWiV 399: Zika la femme
< p > < img class="alignleft size-medium wp-image-7531" src= "http://www.microbe.tv/twiv/wp-content/uploads/sites/2/IMG_3202.jpg" alt="IMG_3202.jpg" width="1" height="1" / > Hosts: < a href= "http://en.wikipedia.org/wiki/Vincent_Racaniello" target= "_blank" > Vincent Racaniello < /a > , < a href= "http://www.verticalfarm.com" target="_blank" > Dickson Despommier < /a > , < a href="http://turbidplaque.com" target= "_blank" > Alan Dove < /a > , and < a href= "http://www.mgm.ufl.edu/faculty/faculty-home-pages/condit-richard-c/" target="_blank" > Rich Condit < /a > < /p > < p > < span style="font-weight: 400;" > The l...
Source: This Week in Virology - MP3 Edition - July 24, 2016 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
TWiV 387: Quaxxed
Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, and
Kathy Spindler
Guest: Nina Martin
Nina Martin joins the TWiV
team to talk about the movie Vaxxed, her bout with dengue fever,
and the latest research on Zika virus.
Links for this episode
Public Health United
Fifty Shades of Science (TEDx)
Parents convicted in death of toddler (Science Based Medicine)
CDC: Zika virus causes microcephaly (NEJM)
Dengue virus antibodies enhance Zika virus infection
(biorXiv)
Zika virus in Brazilian nonhuman primates (biorXiv)
Zika virus IgM in CSF of microcephalic babies
(Lancet)
Brain organoids for modeling Zika virus infe...
Source: This Week in Virology - MP3 Edition - May 1, 2016 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
TWiV 384: Agent 003, a view to a fish kill
Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove and Rich Condit
Guests: Nischay Mishra and Ian Lipkin
Nischay and Ian join the TWiVions to discuss mass die-offs of tilapia by a novel orthomyxo-like virus, Ian's editorial on the movie Vaxxed, and new vaccines to prevent dengue virus infections, including a human challenge model.
Links for this episode
Novel orthomyxo-like virus in Tilapia die-offs (mBio)
Fish flu (TWiV 41)
Anti-vaccination lunacy won't stop (WSJ)
Single-dose dengue vaccine effective (J Inf Dis)
Dengue vaccine needs (J Inf Dis)
Composition of TV003 (J Inf Dis)
Dengue vaccine mutagenesis ...
Source: This Week in Virology - MP3 Edition - April 10, 2016 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
TWiV 383: A zillion Zika papers and a Brazilian
Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove and Kathy Spindler
Guest: Esper Kallas
Esper and the Merry TWiXters analyze the latest data on Zika virus and microcephaly in Brazil, and discuss publications on a mouse model for disease, infection of a fetus, mosquito vector competence, and the cryo-EM structure of the virus particle.
Links for this episode
Zika virus in the Americas (Science)
Co-circulation of dengue, Zika, chik in Brazil (Medicine)
Murine model for Zika virus infection (Am J Trop Med Hyg)
Zika virus susceptibility of A. aegypti and A. albopictus (PLoS NTD)
Infectious Zika virus from sa...
Source: This Week in Virology - MP3 Edition - April 3, 2016 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
TWiV 370: Ten out of 15
Hosts: Vincent Racaniello, Alan Dove, and Kathy Spindler
The TWiVomics review ten captivating virology stories from 2015.
Ten virology stories from 2015
Recoding to make vaccines and study viral functions: TWiV 351: The dengue codeTWiV 362: Gotta catch ’em all and new paper
Defining the virome: TWiV 365: Blood, feuds, and a foodborne disease, TWiV 362: Gotta catch ’em all, TWiV 356: Got viruses?, TWiV 355: Baby’s first virome, TWiV 342: Public epitope #1, TWiV 323: A skid loader full of viromes
Ebola outbreak wanes, vaccines tested, persistence noted: TWiV 361: Zombie viruses on the loose, TWiV 349: One ring ...
Source: This Week in Virology - MP3 Edition - January 3, 2016 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
