Scientists discover how dengue vaccine fails to protect against disease
(University of North Carolina Health Care) Researchers discovered that a small subpopulation of antibodies binding to unique sites on each serotype are linked to protection. The research, published in the Journal of Clinical Investigation, provides important information for vaccine developers to consider when creating a dengue vaccine, which has long eluded scientists. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - June 25, 2021 Category: Infectious Diseases Source Type: news

Clinical and pre-clinical antimicrobial drug development
(Bentham Science Publishers) The ninth volume of 'Frontiers in Anti-Infective Drug Discovery' discusses clinical and pre-clinical antimicrobial drug development, it also focuses on drugs to treat leishmaniosis and dengue fever. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - June 24, 2021 Category: Infectious Diseases Source Type: news

Mosquito love songs send mixed message about immunity
(Cornell University) A new Cornell University study of Aedes aegypti mosquitoes investigates how a mating cue called " harmonic convergence " might affect immunity against parasites, bacteria and dengue virus in offspring, which has important implications for trade-offs male mosquitoes make between investing energy towards immunity or investing it on traits that impact mating and fitness. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - June 24, 2021 Category: Biology Source Type: news

Scientists identify combination of biological markers associated with severe dengue
(eLife) Researchers have identified a combination of biological markers in patients with dengue that could predict whether they go on to develop moderate to severe disease. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - June 22, 2021 Category: Infectious Diseases Source Type: news

Africa: New Research On Wolbachia Is Encouraging in the Fight Against Dengue
[Malaria Consortium] Scientists from the World Mosquito Programme have published new findings from research into the use of Wolbachia to control the spread of dengue via Aedes aegypti mosquitoes. (Source: AllAfrica News: Malaria)
Source: AllAfrica News: Malaria - June 15, 2021 Category: Infectious Diseases Source Type: news

Dengue Infections Can Be Sharply Reduced With Wolbachia Bacteria Dengue Infections Can Be Sharply Reduced With Wolbachia Bacteria
A new study in the New England Journal of Medicine belies the extraordinary 77% protective efficacy reported for preventing dengue infections with Wolbachia-infected Aedes aegypti mosquitoes.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - June 14, 2021 Category: Consumer Health News Tags: Infectious Diseases News Source Type: news

Wolbachia-Infected Mosquitoes Stymie Dengue's Spread: Study
Randomized, controlled research conducted in an Indonesian city confirms the reduction in cases seen with previous observational work. (Source: The Scientist)
Source: The Scientist - June 10, 2021 Category: Science Tags: News & Opinion Source Type: news

Release of Bacteria-Laden Mosquitos Reduces Dengue Incidence by 77% Release of Bacteria-Laden Mosquitos Reduces Dengue Incidence by 77%
As cases of dengue fever make their way into the southern United States, with sometimes-fatal results, a new study in Indonesia offers evidence of an effective way to block the spread of the mosquito-borne infection.Reuters Health Information (Source: Medscape Infectious Diseases Headlines)
Source: Medscape Infectious Diseases Headlines - June 10, 2021 Category: Infectious Diseases Tags: Infectious Diseases News Source Type: news

Florida Woman Dies From Dengue Fever
A Miami woman dies from dengue fever, highlighting the need for awareness of the potentially fatal mosquito-borne virus. (Source: WebMD Health)
Source: WebMD Health - June 10, 2021 Category: Consumer Health News Source Type: news

Woman Dies From Dengue Fever Acquired in Florida
THURSDAY, June 10, 2021 -- The death of a Miami woman in her 30s from locally acquired dengue fever highlights the need for awareness of a potentially fatal mosquito-borne virus that ' s now found in the United States. Once only seen in hot and... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - June 10, 2021 Category: General Medicine Source Type: news

The 10 Most Important Health Breakthroughs You Missed During the Pandemic
While most eyes were on COVID-19, researchers have also made groundbreaking advancements in other fields. Here’s a look. The other big vaccine news Public-health officials have long sought a vaccine against malaria, which infects up to 600 million people a year and kills 400,000, mostly children. This year, there was dramatic prog­ress toward that goal. In a study of 450 children in Burkina Faso, published in the Lancet in April, researchers reported that a new malaria vaccine, called R21, is 77% effective—just clearing the World Health Organization’s 75% efficacy standard. However, the sa...
Source: TIME: Health - June 10, 2021 Category: Consumer Health News Authors: Jeffrey Kluger Tags: Uncategorized COVID-19 feature Innovation Magazine Source Type: news

'Miraculous' mosquito hack cuts dengue by 77%
Infecting the mosquitoes with a different bug slams the brakes on dengue fever, trial finds. (Source: BBC News | Health | UK Edition)
Source: BBC News | Health | UK Edition - June 9, 2021 Category: Consumer Health News Source Type: news

Dengue Vaccine: Takeda Reports Promising Results Dengue Vaccine: Takeda Reports Promising Results
The vaccine appears to have prevented 84% of hospitalizations, and unlike a previous dengue vaccine, no serious adverse events were seen within 3 years.Medscape Medical News (Source: Medscape Infectious Diseases Headlines)
Source: Medscape Infectious Diseases Headlines - June 4, 2021 Category: Infectious Diseases Tags: Infectious Diseases News Source Type: news

A missing antibody molecule may indicate when dengue will become deadly
(Rockefeller University) The antibody's altered structure helps explain an enduring mystery of dengue--why only a fraction of those infected will develop severe disease. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 4, 2021 Category: International Medicine & Public Health Source Type: news

Chimeric viruses unearth hidden gems in dengue virus structure
(Monash University) In a recent study, Australian scientists used an original approach to resolve the 3D structure of flaviviruses with an unprecedented level of detail, identifying small molecules known as 'pocket factors' as new therapeutic targets. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - June 1, 2021 Category: Infectious Diseases Source Type: news