Sanford Burnham Prebys compound advances into Phase 1 trial for pancreatic cancer
(Sanford Burnham Prebys Medical Discovery Institute) A compound discovered at Sanford Burnham Prebys Medical Discovery Institute (SBP) has advanced into a Phase 1 trial for metastatic pancreatic cancer. Called CEND-1 (scientifically known as iRGD), the compound was exclusively licensed in 2015 to a private company, DrugCendR Inc. The drug candidate was discovered in the laboratory of Erkki Ruoslahti, M.D., Ph.D., distinguished professor at SBP and founder, president and CEO of DrugCendR. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 21, 2018 Category: International Medicine & Public Health Source Type: news

$120 million gift from The Anschutz Foundation to CU Anschutz
(University of Colorado Anschutz Medical Campus) The University of Colorado Anschutz Medical Campus has received a $120 million gift, the largest private philanthropic commitment in its history, to further elevate its stature as one of the country's top medical destinations (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 21, 2018 Category: International Medicine & Public Health Source Type: news

New research reveals how the body clock controls inflammation
(RCSI) Researchers at RCSI and Trinity College Dublin have revealed insights into how the body clock controls the inflammatory response, which may open up new therapeutic options to treat excess inflammation in conditions such as asthma, arthritis and cardiovascular disease. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 20, 2018 Category: International Medicine & Public Health Source Type: news

Impact of osteoporosis on the risk of dementia in almost 60,000 patients
(IOS Press) Osteoporosis is estimated to affect 200 million women across the world. In Germany, the prevalence of this chronic disease among people aged 50 years and older is around 15 percent. In recent decades, several authors have analyzed the impact of osteoporosis on the risk of cognitive decline, but, most of these studies have been conducted outside Europe. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 20, 2018 Category: International Medicine & Public Health Source Type: news

Your office may be affecting your health
(University of Arizona) New UA-led research found that open office seating arrangements offer health benefits not seen in workers in cubicles or private offices. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 20, 2018 Category: International Medicine & Public Health Source Type: news

Adults play a key role in children's participation in school recess, researchers suggest
(Oregon State University) When adults are participants in school recess -- leading games, monitoring play and ensuring conflicts are mediated quickly -- children are more likely to be engaged in recess activities, a new study has found. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 20, 2018 Category: International Medicine & Public Health Source Type: news

Temple University Hospital performs nation's 1st post-FDA approval BLVR using Zephyr Valve
(Temple University Health System) Temple University Hospital has become the first US center to perform bronchoscopic lung volume reduction using implantation of the Zephyr ® Endobronchial Valve (Zephyr ® EBV ® ) to treat severe emphysema following US FDA approval. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 20, 2018 Category: International Medicine & Public Health Source Type: news

Stool proteins to predict inflammatory bowel disease
(University of Houston) A University of Houston biomedical engineer is looking for new biomarkers to predict and monitor inflammatory bowel disease (IBD). With $347,490 from the Crohn's& Colitis Foundation of America, Chandra Mohan says protein biomarkers that show up in stools could indicate the disease and make examination and treatment quicker and less invasive. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 20, 2018 Category: International Medicine & Public Health Source Type: news

Healthy diet linked to healthy cellular aging in women
(University of Michigan) Eating a diet that is rich in fruits, vegetables and whole grains and low in added sugar, sodium and processed meats could help promote healthy cellular aging in women, according to a new study published in the American Journal of Epidemiology. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 20, 2018 Category: International Medicine & Public Health Source Type: news

Kids stress over public acts of discrimination, USC study finds
(University of Southern California) USC scientists show an association between concerns over public displays of discrimination and behavioral health problems among teens from communities of color or disadvantaged homes. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 20, 2018 Category: International Medicine & Public Health Source Type: news

Nanoparticles in our environment may have more harmful effects than we think
(University of Southern Denmark) Researchers warn that a combination of nanoparticles and contaminants may form a cocktail that is harmful to our cells. In their study, 72 pct. of cells died after exposure to a cocktail of nano-silver and cadmium ions. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 20, 2018 Category: International Medicine & Public Health Source Type: news

In teen friendships, misery does love company
(Florida Atlantic University) A longitudinal study examined anxiety, depression, social withdrawal, and submissiveness to predict the end of teen friendships. Do friendships end because of one child's mental health problems or do they end because of differences between friends on the degree to which each friend suffers from these problems? Findings show that children's personal struggles need not adversely impact their social relationships, and mental health issues do not necessarily ruin their chances of making and maintaining worthwhile friendships. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 20, 2018 Category: International Medicine & Public Health Source Type: news

Rogue proteins may underlie some ALS and frontotemporal dementia cases, says study
(Columbia University) Some forms of ALS and frontotemporal dementia share a common loss of functioning of RNA-binding   proteins that regulate gene expression,   says a new study by Columbia University and New York Genome Center researchers. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 20, 2018 Category: International Medicine & Public Health Source Type: news

Sex in plants requires thrust
(World Scientific) In a TECHNOLOGY paper to be published in the September 2018 issue of TECHNOLOGY, the thrust produced by the microscopic organ delivering sperm cells in plants has now been measured using microfluidic technology. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 20, 2018 Category: International Medicine & Public Health Source Type: news

Helping surgical patients taper off opioids safely and successfully
(University Health Network) A unique pain program is helping complex surgical patients wean off opioids safely and effectively, while offering alternative ways to cope with their pain and improve how they function. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 20, 2018 Category: International Medicine & Public Health Source Type: news

Organizers of the 2019 Crohn's & Colitis Congress announce agenda & call for abstracts
(American Gastroenterological Association) The Crohn's& Colitis Congress ® , the premier meeting for clinical and research professionals in the IBD space, has opened registration for the 2019 meeting. A partnership of the Crohn's& Colitis Foundation and the American Gastroenterological Association (AGA), the meeting will include four main sessions, as well as basic science sessions and pre-Congress workshops. The 2019 Crohn's& Colitis Congress will take place Feb. 7-9, 2019, at the Bellagio Hotel in Las Vegas. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 20, 2018 Category: International Medicine & Public Health Source Type: news

More than half of stores sampled in Colorado study still selling cigarettes to minors
(University of Colorado Anschutz Medical Campus) Less than half of the 201 randomly chosen stores always refused the underage tobacco purchase attempts, and more than one-fourth sold tobacco to the minors two or more times. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 20, 2018 Category: International Medicine & Public Health Source Type: news

Study finds racial disparities in prescribing opioids for chronic pain
(Yale University) Yale researchers have identified racial disparities in the treatment of patients who are prescribed opioids for chronic pain. Black patients who receive opioids long-term are more likely than whites to be tested for illicit drug use. Of those who test positive, blacks are more likely to have their opioid prescriptions discontinued, said the researchers. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 20, 2018 Category: International Medicine & Public Health Source Type: news

New in ­ form ­ a ­ tion on brain areas linked to tact ­ ile sense and meta ­ cog ­ nit ­ ive abil ­ ity
(University of Helsinki) A new doctoral thesis gives information on the neural basis of the sense of touch. According to the results, magnetic stimulation of prefrontal cortex affected the subjects' performance in tactile tasks, and their ability to evaluate their performance in these tasks. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 20, 2018 Category: International Medicine & Public Health Source Type: news

Proposal seeks to improve assessment of drug risks
(North Carolina State University) A drug policy researcher is proposing a suite of changes to overhaul the Multi-Criteria Drug Harm Scale, which informs drug policies across Europe. The changes focus on addressing use and abuse separately, collecting input from a broader range of stakeholders, and targeting substance-specific experts for drug review panels. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 20, 2018 Category: International Medicine & Public Health Source Type: news

Gene therapy vectors carrying the telomerase gene do not increase the risk of cancer
(Centro Nacional de Investigaciones Oncol ó gicas (CNIO)) Researchers from the Spanish National Cancer Research Centre (CNIO) have shown in a new study that the gene therapy with telomerase that they have developed, and which has proven to be effective in mice against diseases caused by excessive telomere shortening and ageing, does not cause cancer or increase the risk of developing it, even in a cancer-prone setting. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 20, 2018 Category: International Medicine & Public Health Source Type: news

New study explains why genetic mutations cause disease in some people but not in others
(New York Genome Center) Researchers at the New York Genome Center (NYGC) and Columbia University have uncovered a molecular mechanism behind one of biology's long-standing mysteries: why individuals carrying identical gene mutations for a disease end up having varying severity or symptoms of the disease. The study has exciting implications for future prediction of the severity of serious diseases such as cancer and autism spectrum disorder. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 20, 2018 Category: International Medicine & Public Health Source Type: news

Blood management program safely reduces transfusions in orthopedic patients
(American Society of Anesthesiologists) A patient blood management program designed to limit the amount of transfused blood orthopedic patients undergoing common surgeries such as hip and knee replacement receive was associated with fewer transfusions, reduced blood use and improved outcomes, reports a study published in the Online First edition of Anesthesiology, the peer-reviewed journal of the American Society of Anesthesiologists (ASA). (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 20, 2018 Category: International Medicine & Public Health Source Type: news

BU researcher receives DoD grant to study TBI, military service in AD
(Boston University School of Medicine) BU researcher receives three-year, $1.2 million DoD grant to study impact of TBI and military service on Alzheimer's disease and related disorders. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 20, 2018 Category: International Medicine & Public Health Source Type: news

The 5th Annual Aging and Drug Discovery Forum at the Basel Life Conference 2018
(InSilico Medicine, Inc.) Insilico Medicine will present the latest insights into the biomarkers of aging at the 5th Annual Aging Research for Drug Discovery Forum in Basel, Switzerland, Sept. 12-13, 2018.   The 5th Annual Aging and Drug Discovery Forum will cover the latest progress in aging and longevity in the context of drug discovery. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 20, 2018 Category: International Medicine & Public Health Source Type: news

New medical specialty needed to manage growing number of Americans with diabetes
(American Osteopathic Association) Fourteen years after one-year fellowship programs were created to give primary care physicians the clinical skills to better manage diabetes and its complications, new research in the Journal of the American Osteopathic Association finds resistance among payers and other physicians may slow growth of the fledgling specialty. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 20, 2018 Category: International Medicine & Public Health Source Type: news

Safeway Foundation grant awarded to the National Foundation for Cancer Research
(National Foundation for Cancer Research) Safeway Foundation grant awarded to the National Foundation for Cancer Research; Resources will allow for expansion of services to cancer patients. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 20, 2018 Category: International Medicine & Public Health Source Type: news

Bioengineered tooth replacement opens doors to new therapies
(International& American Associations for Dental Research) Tooth loss is a significant health issue currently affecting millions of people worldwide. Two articles published in the September 2018 issue of the Journal of Dental Research share recent advances in bioengineering teeth. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 20, 2018 Category: International Medicine & Public Health Source Type: news

Biological engineers discover new antibiotic candidates
(Massachusetts Institute of Technology) Researchers from MIT and the University of Naples Federico II found that fragments of the protein pepsinogen, an enzyme used to digest food in the stomach, can kill bacteria such as Salmonella and E. coli. Such peptides could potentially be developed as new antibiotics. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 20, 2018 Category: International Medicine & Public Health Source Type: news

Love vine sucks life from wasps, leaving only mummies
(Rice University) Rice University evolutionary biologists have discovered a new trophic interaction -- the first example of a parasitic plant attacking a parasitic insect on a shared host plant. The find is detailed this week in Current Biology and could point to new methods for controlling agricultural pests and perhaps fighting cancer. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 20, 2018 Category: International Medicine & Public Health Source Type: news

Study details effect of radiation exposure on hormone deficiencies
(University of Cincinnati Academic Health Center) In a new study, University of Cincinnati (UC) researchers, in collaboration with Massachusetts General Hospital, have detailed the effect of radiation exposure on the development of hormone deficiency in pediatric and young adult patients treated for brain tumors. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 20, 2018 Category: International Medicine & Public Health Source Type: news

Global surgeons provide value through innovation, professionalism, and education
(American College of Surgeons) A new position paper from the Association of Academic Surgeons (AAS) Global Affairs Committee, the Society of University Surgeons Committee on Global Academic Surgery, and the American College of Surgeons (ACS) Operation Giving Back (OGB) program contends that surgeons from AHCs have much to gain, including professional education, research experience, and an opportunity to enhance their institution's reputation when AHCs support academic global surgeons from their institutions. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 20, 2018 Category: International Medicine & Public Health Source Type: news

Teen tattoos: 1/2 of parents concerned about negative health effects, impact on employment
(Michigan Medicine - University of Michigan) 78 percent of parents said they would 'absolutely not consider it' if their teen asked about a tattoo. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 20, 2018 Category: International Medicine & Public Health Source Type: news

Techniques for reducing sugar content in dairy products show promise
(Elsevier) Dairy foods are popular among consumers, and sales gross more than $125 billion per year (IDFA, 2017). With dairy product popularity comes new demands from consumers for healthier, low-calorie products that taste the same as their higher calorie counterparts. In a report published in the Journal of Dairy Science researchers review the options available to the dairy industry to reduce sugar in products such as ice cream, yogurt, and flavored milk without sacrificing flavor. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 20, 2018 Category: International Medicine & Public Health Source Type: news

Consuming milk at breakfast lowers blood glucose throughout the day
(Elsevier) A change in breakfast routine may provide benefits for the management of type 2 diabetes, according to a new study published in the Journal of Dairy Science. A team of scientists found that milk consumed with breakfast cereal reduced postprandial blood glucose concentration compared with water, and high dairy protein concentration reduced postprandial blood glucose concentration compared with normal dairy protein concentration. The high-protein treatment also reduced appetite after the second meal compared with the low-protein equivalent. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 20, 2018 Category: International Medicine & Public Health Source Type: news

Antidepressant restores youthful flexibility to aging inhibitory neurons in mice
(Picower Institute at MIT) Inhibitory neurons in the aging brain show reduced growth and plasticity, likely contributing to declines in brain function. In a new study in mice researchers at the Picower Institute at MIT show that treatment with fluoxetine restored substantial growth and plasticity. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 20, 2018 Category: International Medicine & Public Health Source Type: news

As body mass index increases, blood pressure may as well
(Yale University) Body mass index is positively associated with blood pressure, according to the ongoing study of 1.7 million Chinese men and women being conducted by researchers at the Yale Center for Outcomes Research and Evaluation (CORE) and in China. These findings appear in the Aug. 17 issue of JAMA Network Open. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 17, 2018 Category: International Medicine & Public Health Source Type: news

Prescriptions for opioid use disorder treatment, opioid pain relievers after ACA Medicaid expansion
(JAMA Network) Medicaid expansion under the Affordable Care Act (ACA) was associated with an overall increase   in people filling prescriptions for buprenorphine with naloxone, which is a treatment for opioid use disorder, as well as an increase in people filling prescriptions for opioid pain relievers (OPRs) paid for by Medicaid in a data analysis from five states. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 17, 2018 Category: International Medicine & Public Health Source Type: news

For children with complex medical situations, a new roadmap for improving health
(University of California - Los Angeles Health Sciences) A team of UCLA researchers has developed a set of health outcome measures for children with medical complexity, using a software program that aggregates the latest research and expertise about how to treat their conditions. The team's work, published in the September issue of the journal Pediatrics, proposes a standard to shape the ideal model of care for such children. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 17, 2018 Category: International Medicine & Public Health Source Type: news

Three factors could explain physician burnout
(University of California - Riverside) In just three years, physician burnout increased from 45.5 percent to 54.4 percent, according to a paper authored by doctors at the University of California, Riverside School of Medicine. They offer three factors that they say contribute to this burnout. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 17, 2018 Category: International Medicine & Public Health Source Type: news

Stroke patients treated at a teaching hospital are less likely to be readmitted
(University of Texas Health Science Center at Houston) Stroke patients appear to receive better care at teaching hospitals with less of a chance of landing back in a hospital during the early stages of recovery, according to new research from The University of Texas Health Science Center at Houston (UTHealth). (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 17, 2018 Category: International Medicine & Public Health Source Type: news

Texas A & M team develops new way to grow blood vessels
(Texas A&M University) Formation of new blood vessels, a process also known as angiogenesis, is one of the major clinical challenges in wound healing and tissue implants. To address this issue, researchers from Texas A&M University have developed a clay-based platform to deliver therapeutic proteins to the body to assist with the formation of blood vessels. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 17, 2018 Category: International Medicine & Public Health Source Type: news

Automated detection of focal epileptic seizures in a sentinel area of the human brain
(University of Alabama at Birmingham) In a first-in-humans pilot study, researchers have identified a sentinel area of the brain that may give an early warning before clinical seizure manifestations from focal epilepsy appear. They have also validated an algorithm that can automatically detect that early warning. These two findings offer the possibility of squelching a focal epilepsy seizure -- before the patient feels any symptoms -- through neurostimulation of the sentinel area of the brain. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 17, 2018 Category: International Medicine & Public Health Source Type: news

Shlomo Benartzi named Distinguished Senior Fellow at Behavior Change for Good Initiative
(University of Pennsylvania) Dr. Shlomo Benartzi has been named a Distinguished Senior Fellow at the University of Pennsylvania's Behavior Change for Good (BCFG) Initiative. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 17, 2018 Category: International Medicine & Public Health Source Type: news

Students more likely to eat school breakfast when given extra time, new study finds
(Virginia Tech) Using food weighting stations, the researchers collected information on the number of students who ate a school breakfast, how much they ate, and their exact nutritional intake. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 17, 2018 Category: International Medicine & Public Health Source Type: news

Perinatal hypoxia associated with long-term cerebellar learning deficits and Purkinje cell misfiring
(Children's National Health System) The type of hypoxia that occurs with preterm birth is associated with locomotor miscoordination and long-term cerebellar learning deficits but can be partially alleviated with an off-the-shelf medicine, according to a study using a preclinical model. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 17, 2018 Category: International Medicine & Public Health Source Type: news

Making aquafeed more sustainable: Scientists develop feeds using a marine microalga co-product
(Dartmouth College) Dartmouth scientists have created a more sustainable feed for aquaculture by using a marine microalga co-product as a feed ingredient. The study is the first of its kind to evaluate replacing fishmeal with a co-product in feed designed specifically for Nile tilapia. The results are published in the open access journal, PLOS ONE. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 17, 2018 Category: International Medicine & Public Health Source Type: news

Experiences at first sexual encounter impact risk of HIV and violence for women in Kenya
(St. Michael's Hospital) Adolescent girls and young women in Mombasa, Kenya are more likely to experience higher risks of HIV and gender-based violence when they are involved with sex work venues or have sexual experiences at a young age, suggests a study co-led by St. Michael's Hospital and the University of Manitoba in Canada. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 17, 2018 Category: International Medicine & Public Health Source Type: news

New research highlights promising treatments, genetic causes of obesity
(American Gastroenterological Association) More than 60 percent of American adults weigh more than is healthy, which results in increased health issues for the patient and high health care costs. The 2018 AGA James W. Freston Conference, taking place Aug. 18-19, 2018, in Arlington, Virginia, will bring together leading physicians and researchers to discuss current research and techniques to help combat the growing epidemic of obesity. Here we summarize three of the most impactful obesity abstracts to be presented as oral presentations. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 17, 2018 Category: International Medicine & Public Health Source Type: news

Patients, doctors dissatisfied by Electronic Health Records
(Lehigh University) Electronic Health Records are intended to streamline and improve access to information -- and have been shown to improve quality of care -- but a new study shows they also leave both doctors and patients unsatisfied, even after full implementation. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 17, 2018 Category: International Medicine & Public Health Source Type: news