Rare mutation of gene carried by Quebec family gives insight into how the brain is wired
(McGill University) The study of a Quebec family with an unusual gene provides novel insight into how our brain is built and, according to the McGill-led team of scientists, offers a better understanding of psychiatric disorders such as depression, addictions and schizophrenia. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 18, 2018 Category: International Medicine & Public Health Source Type: news

Algorithm speeds up process for analyzing 3D medical images
(Massachusetts Institute of Technology) In a pair of upcoming conference papers, MIT researchers describe a machine-learning algorithm that can register brain scans and other 3D images more than 1,000 times more quickly using novel learning techniques. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 18, 2018 Category: International Medicine & Public Health Source Type: news

BIDMC researchers develop decision-making tool to benefit patients with HCV
(Beth Israel Deaconess Medical Center) BIDMC researchers led a retrospective analysis of four randomized clinical trials focused on the effects of DAA therapies in patients with HCV-associated liver failure, and developed a new means of predicting improvement in liver function in response to DAA treatment. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 18, 2018 Category: International Medicine & Public Health Source Type: news

Researchers create novel combination as potential therapy for high-risk neuroblastoma
(Virginia Commonwealth University) Researchers at VCU Massey Cancer Center in Richmond, Virginia, have identified a promising target to reverse the development of high-risk neuroblastoma and potentially inform the creation of novel combination therapies for the disease. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 18, 2018 Category: International Medicine & Public Health Source Type: news

BU researcher recognized for outstanding contributions in the field of spondyloarthritis
(Boston University School of Medicine) Maureen Dubreuil, M.D., MSc, assistant professor of Clinical Epidemiology Research& Training at Boston University School of Medicine (BUSM), is one of two recipients of the 2018 Spondylitis Association of America (SAA) Bruckel Early Career Investigator in Axial Spondyloarthritis Award. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 18, 2018 Category: International Medicine & Public Health Source Type: news

Violence against women significantly more likely after high-risk sex
(Mary Ann Liebert, Inc./Genetic Engineering News) A study of the victimization of women who were living in areas of high poverty and HIV prevalence in multiple cities across the US has shown that high-risk-sex, characterized by one or more HIV risk factors, was associated with a significantly greater likelihood of physical violence against the female participant within the subsequent six months. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 18, 2018 Category: International Medicine & Public Health Source Type: news

Research shows how a moderate dose of alcohol protects the heart
(Funda ç ã o de Amparo à Pesquisa do Estado de S ã o Paulo) Results published in Cardiovascular Research suggest the effect is associated with activation of the enzyme ALDH2, which helps rid the organism of an aldehyde which is a toxic byproduct of alcohol digestion as much as it is a byproduct of heart cells submitted to stress. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 18, 2018 Category: International Medicine & Public Health Source Type: news

Compilation of research discussed at the Global Forum On Nicotine: Warsaw June 16 2018
(Abzed) Below is a summary of the new and recent research discussed at this conference. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 18, 2018 Category: International Medicine & Public Health Source Type: news

Reducing the risk of dementia through lifestyle changes
(Baycrest Centre for Geriatric Care) Canadian researchers are recruiting older adults across Toronto and Montreal to explore the benefits of different types of brain training and lifestyle interventions for two clinical trials. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 18, 2018 Category: International Medicine & Public Health Source Type: news

New method to preserve boy cancer patient fertility being developed at Ben-gurion U.
This study may open the way for new therapeutic strategies for fertility preservation of PCPBs and for azoospermic patients. " (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 18, 2018 Category: International Medicine & Public Health Source Type: news

Neuroscientists map brain's response to cold touch
(Carnegie Mellon University) Carnegie Mellon neuroscientists have mapped the feeling of cool touch to the brain's insula in a mouse model. The findings provide an experimental model that will advance research into conditions like pain and hypersensitivity to cold and help researchers to continue to unravel the multifaceted ways touch is represented in the brain. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 18, 2018 Category: International Medicine & Public Health Source Type: news

Insilico to present latest advances in Machine Learning & Artificial Intelligence for drug discovery
(InSilico Medicine, Inc.) Insilico Medicine presents at the Advanced Machine Learning and Artificial Intelligence for Drug Discovery& Development Conference, organized by BIS Group. The presentation will focus on the application of Generative Adversarial Networks (GANs) for generation of novel small organic molecules with the desired set of pharmacological properties. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 18, 2018 Category: International Medicine & Public Health Source Type: news

Risky opioid prescriptions linked to higher chance of death
(RAND Corporation) Most people who misuse opioids are first exposed to the drugs through prescriptions so improving prescribing is targeted as one way to help curb the nation's opioid abuse epidemic. A new study identified six types of risky opioid prescriptions and found that all were linked to a higher chance of death, including fatal opioid overdoses. The study found more than 6 percent of Massachusetts adults received a risky opioid prescription during a five-year period. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 18, 2018 Category: International Medicine & Public Health Source Type: news

Novel information about the effects of in vitro fertilization on embryonic growth
(University of Helsinki) In vitro fertilization affects the regulatory region of genes essential for placental and embryonic growth, as well as the birth weight. A new study suggests that the effects depend on genetic variation inherited from the parents. This information could be useful in development of assisted reproduction technologies. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 18, 2018 Category: International Medicine & Public Health Source Type: news

Plant-based diets improve cardiometabolic risk factors in diabetes patients
(Physicians Committee for Responsible Medicine) New review in the journal Clinical Nutrition finds that plant-based diets improve cardiometabolic risk factors in those with type 2 diabetes. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 18, 2018 Category: International Medicine & Public Health Source Type: news

Targeting the engine room of the cancer cell
(Columbia University Irving Medical Center) Researchers at Columbia University Irving Medical Center (CUIMC) have developed a highly innovative computational framework that can support personalized cancer treatment by matching individual tumors with the drugs or drug combinations that are most likely to kill them. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 18, 2018 Category: International Medicine & Public Health Source Type: news

Unique immune-focused AI model creates largest library of inter-cellular communications
(CytoReason) New data published in Nature Biotech, represents the largest ever analysis of immune cell signaling research, mapping more than 3,000 previously unlisted cellular interactions, and yielding the first ever immune-centric modular classification of diseases. These data serve to rewrite the reference book on immune-focused inter-cellular communications and disease relationships.New Data Published by Nature Biotechnology: Covering 16,000,000 scientific articles, this massive Natural Language Processing (NLP) project quadruples the reference body of organized inter-cellular signalling interactions, plots inter-cellu...
Source: EurekAlert! - Medicine and Health - June 18, 2018 Category: International Medicine & Public Health Source Type: news

CHEST ® partners with Medscape to launch the moderate to severe asthma center of excellence
(American College of Chest Physicians) The American College of Chest Physicians (CHEST) announces a new partnership with Medscape focused on supporting physicians in addressing the challenges of diagnosing and treating moderate to severe asthma. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 18, 2018 Category: International Medicine & Public Health Source Type: news

New asthma tool determines best treatment for severe asthma patients
(American College of Chest Physicians) To help enable stronger communication and understanding between the clinician and patient, the CHEST Foundation, the charitable foundation of the American College of Chest Physicians, Allergy& Asthma Network and American College of Allergy, Asthma& Immunology (ACAAI) have partnered to launch a new digital, interactive Shared Decision Making Tool. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 18, 2018 Category: International Medicine & Public Health Source Type: news

Carbon nanotube optics provide optical-based quantum cryptography and quantum computing
(DOE/Los Alamos National Laboratory) Researchers at Los Alamos and partners in France and Germany are exploring the enhanced potential of carbon nanotubes as single-photon emitters for quantum information processing. Their analysis of progress in the field is published in this week's edition of the journal Nature Materials. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 18, 2018 Category: International Medicine & Public Health Source Type: news

AcuraStem receives fast-track SBIR grant
(AcuraStem, Inc.) AcuraStem, a fast-growing and innovative biotech company located in Monrovia, California, has been awarded a 3.7 million dollar Small Business Innovation Research (SBIR) Fast-Track grant (#R44NS105156) by the National Institute of Neurological Disorders and Stroke (NINDS) to continue research for the development of a small molecule therapeutic, 'AS2015', focused on treating patients with the genetic form of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) caused by expansion repeats in the gene C9ORF72. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 18, 2018 Category: International Medicine & Public Health Source Type: news

Purdue phoneme project creates new haptic communications future
(Purdue University) Communication could step beyond reading a cellular phone screen with a new technique by Purdue College of Engineering researchers to learn and read messages through a person's sense of touch. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 18, 2018 Category: International Medicine & Public Health Source Type: news

Studying the brain at work: Drexel to host International Neuroergonomics Conference
(Drexel University) More than 100 experts will convene to discuss the emerging field of research, which aims to design systems for safer, more efficient operations and to advance the understanding of the relationship between the brain and everyday human tasks. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 18, 2018 Category: International Medicine & Public Health Source Type: news

The force is strong within us: New study explores cell mechanics at work
(Arizona State University) An ASU research team focused on measuring the stiffness, bending, twisting and viscosity of individual cells -- focused on a breast cancer cell line -- using all of the most state-of-the art technology at their disposal. How both healthy and cancerous cells respond to this environment -- and whether there are key differences that can be identified for future diagnostic applications was of keen interest to both the NCI and the physicists taking on the NCI's challenge. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 18, 2018 Category: International Medicine & Public Health Source Type: news

Better implants key to repair damaged knees
(Stellenbosch University) People whose knees have been affected by osteoarthritis, also known as the 'wear and tear' arthritis, often have to get knee implants to repair the damage. But if a knee implant does not fit the specific individual, it could lead to soft tissue damage, collapsing of the underlying bone, loosening of the implant and an increased likelihood of joint pain after an operation. One possible solution is to design implants that are patient-specific, anatomically accurate, reproduce normal knee motion and are ultimately repeatable. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 18, 2018 Category: International Medicine & Public Health Source Type: news

Sensitive new assay finds abnormalities in tumor cells that other techniques may miss
This study paves the way for clinical use to advance the diagnosis and treatment of solid tumors. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 18, 2018 Category: International Medicine & Public Health Source Type: news

One in 5 parents did not talk to kids about what to do if they got lost at an amusement park
(Michigan Medicine - University of Michigan) New report indicates several opportunities to reduce safety risks for children in the amusement park environment. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 18, 2018 Category: International Medicine & Public Health Source Type: news

Researchers find a promising new approach for treating liver cirrhosis
(Elsevier) In a study in The American Journal of Pathology, investigators report that treatment with aleglitazar, a dual peroxisome proliferator-activated receptor-alpha/gamma (PPARα/γ) agonist, reduced inflammation, vasoconstriction, angiogenesis, mucosal disruption, and tumor necrosis factor (TNF)-α overproduction in cirrhotic rats with PH. This suggests a promising new approach for treating liver cirrhosis. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 18, 2018 Category: International Medicine & Public Health Source Type: news

When it comes to weight loss in overweight and obese adults with knee osteoarthritis, more is better
(Wiley) Researchers previously showed that overweight and obese individuals with knee osteoarthritis can reduce pain by 50 percent and significantly improve function and mobility with a 10 percent or more weight loss over an 18-month period. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 18, 2018 Category: International Medicine & Public Health Source Type: news

Diabetes may be an early manifestation of pancreatic cancer
(Oxford University Press USA) A new study in the Journal of the National Cancer Institute indicates that recent-onset type 2 diabetes may be early expression of pancreatic cancer. Diabetes was associated with a more than twofold higher risk of pancreatic cancer in African-Americans and Latinos, but recent-onset diabetes was associated with a 2.3-fold greater increase in risk of pancreatic cancer than long-standing diabetes. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 18, 2018 Category: International Medicine & Public Health Source Type: news

Rising sea temperatures threaten survival of juvenile albatross
(British Ecological Society) Changes in sea surface temperature affect the survival of albatross during their first year at sea, resulting in a reduced population growth rate when temperatures are warmer than the current average, a new study published in the Journal of Animal Ecology has revealed. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 18, 2018 Category: International Medicine & Public Health Source Type: news

Americans view child abuse and neglect as a serious public health problem
(Research!America) A strong majority of Americans view child abuse and neglect as a public health problem in the United States, a sentiment shared across populations with 81 percent of Hispanics, 76 percent of non-Hispanic whites, 74 percent of African-Americans and 67 percent of Asians in agreement, according to a new survey commissioned by Research!America and the National Foundation to End Child Abuse and Neglect (EndCAN). (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 18, 2018 Category: International Medicine & Public Health Source Type: news

Valuing gluten-free foods relates to health behaviors in young adults
(Elsevier) In a new study featured in the Journal of the Academy of Nutrition and Dietetics, researchers found that among young adults valuing gluten-free foods could be indicative of an overall interest in health or nutrition. These young adults were more likely to engage in healthier behaviors including better dietary intake and also valued food production practices (e.g., organic, non-GMO, locally sourced). Of concern, they were also more likely to engage in unhealthy weight control behaviors and over-concern about weight. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 18, 2018 Category: International Medicine & Public Health Source Type: news

Silence is golden when it comes to how our brains work
(Medical College of Georgia at Augusta University) It's the comparative silence between the firing spikes of neurons that tells what they are really up to, scientists report. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 18, 2018 Category: International Medicine & Public Health Source Type: news

Gut microbes may contribute to depression and anxiety in obesity
(Joslin Diabetes Center) Like everyone, people with type 2 diabetes and obesity suffer from depression and anxiety, but even more so. Researchers at Joslin Diabetes Center now have demonstrated a surprising potential contributor to these negative feelings -- and that is the bacteria in the gut or gut microbiome, as it is known. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 17, 2018 Category: International Medicine & Public Health Source Type: news

World's largest autism grant will transform research landscape
(King's College London) The largest research grant ever given for neurodevelopmental conditions has been awarded by the Innovative Medicines Initiative to an international consortium academically led by the Institute of Psychiatry, Psychology& Neuroscience (IoPPN) at King's College London. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 17, 2018 Category: International Medicine & Public Health Source Type: news

Gene signatures and biomarkers predict onset of RA in at-risk individuals
(European League Against Rheumatism) The results of two studies presented today at the Annual European Congress of Rheumatology (EULAR 2018) provide insight into molecular changes prior to the onset of arthritis which could inform future novel diagnostics and early therapeutic interventions. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 15, 2018 Category: International Medicine & Public Health Source Type: news

New treatment lenebasum shows promise for diffuse cutaneous systemic sclerosis (dcSSc)
(European League Against Rheumatism) The results of an open label extension of a phase II study presented today at the Annual European Congress of Rheumatology (EULAR 2018) demonstrate that lenabasum continues to have acceptable safety and tolerability in diffuse cutaneous systemic sclerosis (dcSSc) with no severe or serious adverse events (AE). (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 15, 2018 Category: International Medicine & Public Health Source Type: news

Zoledronic acid has no effect on knee pain or bone marrow lesions in knee OA after two years
(European League Against Rheumatism) The results of a study presented today at the Annual European Congress of Rheumatology (EULAR 2018) show that a one-yearly infusion of zoledronic acid (ZA) did not significantly reduce knee pain or bone marrow lesion (BML) size overall in knee osteoarthritis patients over two years. However, it may have symptomatic benefit in milder disease. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 15, 2018 Category: International Medicine & Public Health Source Type: news

Canakinumab shown to reduce rates of gout in atherosclerosis by more than half
(European League Against Rheumatism) The results of a study presented today at the Annual European Congress of Rheumatology (EULAR 2018) demonstrate that canakinumab significantly reduced the rate of gout by more than half compared to placebo, regardless of baseline serum urate level. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 15, 2018 Category: International Medicine & Public Health Source Type: news

Early, intensive treatment of RA offers long-term benefits, may normalise mortality rates
(European League Against Rheumatism) The results of a 23-year, follow-up study presented today at the Annual European Congress of Rheumatology (EULAR 2018) suggest early, intensive treatment of rheumatoid arthritis has long-term benefits including the normalization of mortality to levels consistent with the general population. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 15, 2018 Category: International Medicine & Public Health Source Type: news

QUT to put grass pollen research to Swiss nanotech
(Queensland University of Technology) Queensland University of Technology (QUT) in Brisbane, Australia, and Swiss medtech company Abionic SA are collaborating to develop rapid, targeted tests for allergies to subtropical grass pollens -- tests that could be administered in a GP office. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 15, 2018 Category: International Medicine & Public Health Source Type: news

Queen Mary spinout secures £ 2 million pounds to export toothpaste technology to China
(Queen Mary University of London) A Queen Mary University of London spinout has secured a license agreement with a leading Chinese toothpaste manufacturer, which should generate sales of £ 2 million pounds over the next five years. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 15, 2018 Category: International Medicine & Public Health Source Type: news

Florida's obesity rate may be higher than originally thought, new study finds
(University of Florida) Florida's obesity rate may be higher than originally thought. A widely used national health survey puts the overall obesity rate in the state at 27.8 percent, but a new study based on an analysis of a robust clinical data repository shows a rate of 37.1 percent -- nearly 10 percentage points higher. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 15, 2018 Category: International Medicine & Public Health Source Type: news

University of Cincinnati scientist receives $2 million NHLBI grant to study atherosclerosis
(University of Cincinnati Academic Health Center) Research scientist Phillip Owens, III, PhD, hopes to find a better treatment for a leading cause of heart disease by unlocking how a cell associated receptor--protease-activated receptor 2 (PAR2) --elicits cellular change and inflammation leading to atherosclerosis. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 15, 2018 Category: International Medicine & Public Health Source Type: news

Loving the sweet enemy
(Max-Planck-Gesellschaft) Foods rich in fats and carbohydrates stimulate the reward system in the brain particularly strongly. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 15, 2018 Category: International Medicine & Public Health Source Type: news

Study with implications for opioid crisis finds opioids raise risk of fracture nonunion
(Louisiana State University Health Sciences Center) Dr. Robert Zura, Professor and Chair of Orthopaedic Surgery at LSU Health New Orleans School of Medicine, was part of a research team reporting that not only may opioid use increase the risk of bone fractures, but opioids may also impair healing. The authors also question their effectiveness in controlling pain. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 15, 2018 Category: International Medicine & Public Health Source Type: news

Diabetes Emergency Relief Coalition honored for hurricane response
(The Endocrine Society) The Diabetes Emergency Relief Coalition, composed of the Endocrine Society and seven other leading diabetes care and research organizations, received an American Society of Association Executives (ASAE) 2018 Gold Power of A Award for helping to provide critical diabetes supplies to regions impacted by Hurricanes Harvey and Irma, the Society announced today. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 15, 2018 Category: International Medicine & Public Health Source Type: news

Brain matures faster due to childhood stress
(Radboud University Nijmegen) Stress in early childhood leads to faster maturation of certain brain regions during adolescence. In contrast, stress experienced later in life leads to slower maturation of the adolescent brain. This is the outcome of a long-term study conducted by researchers of Radboud University in which 37 subjects have been monitored for almost 20 years. The findings will be published in Scientific Reports on June 15. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 15, 2018 Category: International Medicine & Public Health Source Type: news

Gout in the elderly linked to higher risk of dementia
(European League Against Rheumatism) The results of a study presented today at the Annual European Congress of Rheumatology (EULAR 2018) suggest that gout is associated with a 17-20 percent higher risk of dementia in the elderly. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 15, 2018 Category: International Medicine & Public Health Source Type: news