WHO expert panel strongly advises against use of hydroxychloroquine to prevent covid-19
(BMJ) The anti-inflammatory drug hydroxychloroquine should not be used to prevent infection in people who do not have covid-19, say a WHO Guideline Development Group (GDG) panel of international experts inThe BMJ today. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 1, 2021 Category: International Medicine & Public Health Source Type: news

Why some rural enrollees in Medicare Advantage are switching to traditional Medicare
(Drexel University) More than one out of every 10 seniors (10.5%) enrolled in a Medicare Advantage plan, also known as a Medicare managed care option, and living in a rural area, switched to traditional Medicare during 2010-2016. The switch was driven primarily due to low satisfaction with care access, according to a study published this week in Health Affairs from researchers at Drexel University's Dornsife School of Public Health. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 1, 2021 Category: International Medicine & Public Health Source Type: news

Addressing a complex world of pain in a single gene difference
(Wiley) A new review published by Wiley in the journal Advanced Genetics analyzes disparities in experience and treatment of sickle cell disease. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 1, 2021 Category: International Medicine & Public Health Source Type: news

Alcohol and tobacco sales climb during early months of COVID-19 pandemic
(University of Southern California - Health Sciences) Alcohol and tobacco sales nationwide rose in the early months of COVID-19, according to a study appearing in the Annals of Internal Medicine today. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 1, 2021 Category: International Medicine & Public Health Source Type: news

Post-COVID solutions to improve health in the US subject of new book by CUNY professor
(CUNY Graduate School of Public Health and Health Policy) The ways in which the American economic and political systems have failed to protect citizens of all ages and backgrounds -- and the opportunities we have as a nation post-COVID to change our policies and processes in order to improve public health for everyone -- is the subject of a new book by CUNY Graduate School of Public Health and Health Policy (CUNY SPH) Distinguished Professor Nicholas Freudenberg. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 1, 2021 Category: International Medicine & Public Health Source Type: news

Black Americans report high levels of vaccine hesitancy
(RAND Corporation) Black Americans are often skeptical about the nation's health care system, a result of systemic racism. A new survey finds that Black Americans have a high level of vaccine hesitancy and mistrust of COVID-19 vaccines, including among Black health care workers. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 1, 2021 Category: International Medicine & Public Health Source Type: news

Benign bone tumors are common in kids -- historical X-rays lend new insights
(Wolters Kluwer Health) Benign bone tumors may be present in nearly 20 percent of healthy children, based on a review of historical radiographs in The Journal of Bone& Joint Surgery. The journal is published in the Lippincott portfolio in partnership with Wolters Kluwer. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 1, 2021 Category: International Medicine & Public Health Source Type: news

Swapping alpha cells for beta cells to treat diabetes
(UT Southwestern Medical Center) Blocking cell receptors for glucagon, the counter-hormone to insulin, cured mouse models of diabetes by converting glucagon-producing cells into insulin producers instead, a team led by UT Southwestern reports in a new study. The findings, published online in PNAS, could offer a new way to treat both Type 1 and Type 2 diabetes in people. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 1, 2021 Category: International Medicine & Public Health Source Type: news

Increase in medicaid managed care for youth linked to slightly more preventive care
(Ann& Robert H. Lurie Children's Hospital of Chicago) While managed care has become the predominant form of Medicaid coverage for youth, researchers found only a modest increase in the receipt of preventive care services in this population, with marked variation across states. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 1, 2021 Category: International Medicine & Public Health Source Type: news

School-based dental program reduces cavities by more than 50%
(New York University) A school-based cavity prevention program involving nearly 7,000 elementary school students reduced cavities by more than 50 percent, according to a study led by researchers at NYU College of Dentistry. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 1, 2021 Category: International Medicine & Public Health Source Type: news

Researchers find frustration is an additional factor of addiction
(University of Texas Medical Branch at Galveston) New paper published in Psychopharmacology by researchers at the University of Texas Medical Branch shows frustration is additional factor that can lead to addiction escalation. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 1, 2021 Category: International Medicine & Public Health Source Type: news

Top diversity and equity leaders in psychiatry offer guidelines for academic medicine
(American Psychiatric Association) Diversity, equity and inclusion (DEI) leaders in academic medicine are subject to increasing expectations with limited resources and there is an urgent need for psychiatry departments to commit to fully supporting their efforts, according to an article now available in the American Journal of Psychiatry written by top DEI leaders in academic psychiatry from across the country. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 1, 2021 Category: International Medicine & Public Health Source Type: news

Single cell sequencing opens new avenues for eradicating leukemia at its source
(Center for Genomic Regulation) Cancer stem cells that elude conventional treatments like chemotherapy drive long-term cancer growth and relapse. These cells are difficult to isolate and study because of their low abundance and similarity to other stem cells. Researchers have created a new method that can distinguish cancer stem cells, mature cancer cells and otherwise healthy stem cells based on their genetics and gene expression. The findings open new avenues for cancer research personalised medicine. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 1, 2021 Category: International Medicine & Public Health Source Type: news

Financial incentives for hospitals boost rapid changes to opioid use disorder treatment
(University of Pennsylvania School of Medicine) In a new study, researchers at the Penn Medicine evaluated the efficacy of the Opioid Hospital Quality Improvement Program, pioneered by Pennsylvania in 2019, revealing that financial incentives for hospitals are effective in producing rapid treatment innovations for opioid use disorder, including increasing the rate of follow-up treatment for Medicaid patients within seven days of an ED encounter. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 1, 2021 Category: International Medicine & Public Health Source Type: news

March SLAS Discovery explores COVID-19 drug therapies six months later
(SLAS (Society for Laboratory Automation and Screening)) The March edition of SLAS Discovery features the cover article, 'Therapeutic and Vaccine Options for COVID-19: Status After 6 Months of the Disease Outbreak' by Christian Ogaugwu (Federal University Oye-Ekiti, Ekiti State, Nigeria ), Dawid Maciorowski, Subba Rao Durvasula, Ph.D., Ravi Durvasula, M.D., and Adinarayana Kunamneni, Ph.D. (Loyola University Medical Center, Maywood, IL, USA). (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 1, 2021 Category: International Medicine & Public Health Source Type: news

Microplastic sizes in Hudson-Raritan Estuary and coastal ocean revealed
(Rutgers University) Rutgers scientists for the first time have pinpointed the sizes of microplastics from a highly urbanized estuarine and coastal system with numerous sources of fresh water, including the Hudson River and Raritan River. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 1, 2021 Category: International Medicine & Public Health Source Type: news

Paper addresses research needed to understand smoking and COVID-19
(American Thoracic Society) A new paper published online in theAnnals of the American Thoracic Society discusses how smoking may affect risk for COVID-19 and the types of research that are needed to better understand the link between smoking and COVID-19 risk. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 1, 2021 Category: International Medicine & Public Health Source Type: news

'Silent epidemic of grief' leaves bereaved and bereavement care practitioners struggling
(University of Cambridge) Major changes in bereavement care have occurred during the COVID-19 pandemic, amid a flood of demand for help from bereaved people, according to new research from the University of Cambridge. The first major study of pandemic-related changes in bereavement care has found that the switch to remote working has helped some services to reach out, but many practitioners feel they do not have capacity to meet people's needs. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 28, 2021 Category: International Medicine & Public Health Source Type: news

Predicts the onset of Alzheimer's Disease (AD) using deep learning-based Splice-AI
This study reported for the first time, which identified the gene mutations and abnormal splicing of PLCg1 gene in AD using both high-throughput screening data and a deep learning-based prediction (Splice-AI) (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 27, 2021 Category: International Medicine & Public Health Source Type: news

Advanced practice nurses reduce hospitalizations from nursing home residents
(University of Missouri-Columbia) Marilyn Rantz still remembers the day she got the call that her mother, whose health had been declining, had fallen and fractured her shoulder. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 26, 2021 Category: International Medicine & Public Health Source Type: news

Early PDA closure may improve outcomes in preterm infants
(Le Bonheur Children's Hospital) Extremely low birth weight (ELBW) infants with moderate to large patent ductus arteriosus (PDA) may benefit from transcatheter PDA closure (TCPC) in the first four weeks of life, according to research published by Le Bonheur Cardiologist Ranjit Philip, MD, and Medical Director of Interventional Cardiac Imaging and Interventional Catheterization Laboratory Shyam Sathanandam, MD. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 26, 2021 Category: International Medicine & Public Health Source Type: news

How housing discrimination affects environmental inequality
(University of Illinois College of Agricultural, Consumer and Environmental Sciences) Economists and urban planners generally agree that local pollution sources disproportionally impact racial minorities in the U.S. The reasons for this are largely unclear, but a University of Illinois study provides new insights into the issue. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 26, 2021 Category: International Medicine & Public Health Source Type: news

Blood tests offer early indicator of severe COVID-19, study says
(Yale University) When patients with COVID-19 arrive in emergency rooms, there are relatively few ways for doctors to predict which ones are more likely to become critically ill and require intensive care and which ones are more likely to enjoy a quick recovery. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 26, 2021 Category: International Medicine & Public Health Source Type: news

New research finds exercise may help slow memory loss for people living with Alzheimer's dementia
(IOS Press) Promising new research shows aerobic exercise may help slow memory loss for older adults living with Alzheimer's dementia. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 26, 2021 Category: International Medicine & Public Health Source Type: news

Exposure to diverse career paths can help fill labor market 'skills gap'
(University of Missouri-Columbia) When Patrick Rottinghaus began college, he had no idea what he wanted to do with his career. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 26, 2021 Category: International Medicine & Public Health Source Type: news

New journal launched, The International Journal of Gastroenterology & Hepatology Diseases
(Bentham Science Publishers) Bentham Science is pleased to announce the launch of new subscription-based journal, The International Journal of Gastroenterology and Hepatology Diseases. The first issue of the journal will be available online by the start of the year, 2021. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 26, 2021 Category: International Medicine & Public Health Source Type: news

Bentham Science launches new journal, < i > Current Cosmetic Science < /i >
(Bentham Science Publishers) Bentham Science is pleased to announce the launch of a new subscription-based journal,Current Cosmetic Science. The first issue of the journal will be available online by the start of the year, 2021. The journal is edited by Dr. Syed A.A. Rizvi. Dr. Syed Rizvi is currently associated with Hampton University, Hampton, VA, USA. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 26, 2021 Category: International Medicine & Public Health Source Type: news

C-Path and Global Partners launch Ataxia Consortium
(Critical Path Institute (C-Path)) Critical Path Institute today announced the launch of the Critical Path to Therapeutics for the Ataxias Consortium, a public-private partnership focused on optimizing clinical trials for inherited ataxias. CPTA is a collaborative effort between C-Path, Ataxia Global Initiative, the National Ataxia Foundation, Ataxia UK and key partners in the industry and academic research communities, including Biohaven Pharmaceuticals, Ionis Pharmaceuticals, Roche Pharmaceuticals, Servier Group, Triplet Therapeutics, uniQure, and Vico Therapeutics. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 26, 2021 Category: International Medicine & Public Health Source Type: news

Cerium sidelines silver to make drug precursor
(Rice University) Rice University scientists have developed a greatly simplified method to make fluoroketones, a precursor for drug design and manufacture that typically requires an expensive silver catalyst. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 26, 2021 Category: International Medicine & Public Health Source Type: news

Researchers identify characteristics of highest utilizers for mental health hospital services
(University of Texas Health Science Center at Houston) Dropping out of high school, having schizophrenia, or being diagnosed with a co-occurring personality disorder increases the likelihood of someone becoming a 'high utilizer' of inpatient psychiatric hospital services, according to a new study by researchers at UTHealth. A high utilizer is someone who has been admitted three or more times within one year. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 26, 2021 Category: International Medicine & Public Health Source Type: news

Sensing robot healthcare helpers being developed at SFU
(Simon Fraser University) Robots that could take on basic healthcare tasks to support the work of doctors and nurses may be the way of the future. Who knows, maybe a medical robot can prescribe your medicine someday? That's the idea behind 3D structural-sensing robots being developed and tested at Simon Fraser University by Woo Soo Kim, associate professor in the School of Mechatronic Systems Engineering. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 26, 2021 Category: International Medicine & Public Health Source Type: news

Deep brain stimulation and exercise restore movement in ataxia
(Baylor College of Medicine) New research from Baylor College of Medicine scientists shows that a combination of deep brain stimulation (DBS) and exercise has potential benefits for treating ataxia, a rare genetic neurodegenerative disease characterized by progressive irreversible problems with movement. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 26, 2021 Category: International Medicine & Public Health Source Type: news

Atherosclerosis can accelerate the development of clonal hematopoiesis, study finds
(Massachusetts General Hospital) Studies have shown that clonal hematopoiesis often goes hand in hand with atherosclerosis and cardiovascular disease. Since its discovery, this surprising association has been the subject of intense interest from clinicians and researchers alike. Patients with atherosclerosis suffer from hyperlipidemia and inflammation, two conditions that are known to chronically boost hematopoietic stem cell division rates. In the new study, the researchers now demonstrate that this increased division accelerates the development of clonal hematopoiesis. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 26, 2021 Category: International Medicine & Public Health Source Type: news

University of Minnesota to host webinar - Is COVID-19 changing research ethics?
(University of Minnesota) On Wednesday, March 3, the University of Minnesota will host top national experts to debate how COVID-19 is changing the rules and conduct for research. This webinar on 'Conducting Research in the COVID-19 Pandemic: Ethics in an Emergency' will tackle huge issues. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 26, 2021 Category: International Medicine & Public Health Source Type: news

Picture books can boost physical activity for youth with autism
(University of Missouri-Columbia) While physical activity is important for everyone, research has shown people with developmental disabilities do not exercise as often as their typically developed peers. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 26, 2021 Category: International Medicine & Public Health Source Type: news

Oahu marine protected areas offer limited protection of coral reef herbivorous fishes
(University of Hawaii at Manoa) Marine protected areas around O?ahu do not adequately protect populations of herbivorous reef fishes that eat algae on coral reefs. That is the primary conclusion of a study published in Coral Reefs by researchers from the University of Hawai?i at Mānoa. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 26, 2021 Category: International Medicine & Public Health Source Type: news

UTA researcher explores effects of trauma at the cellular, tissue levels of the brain
(University of Texas at Arlington) Ashfaq Adnan, professor of mechanical and aerospace engineering, has received a three-year, $944,845 grant to study the potential link between blast-like trauma and cellular and tissue damage in the brain. By using ultra-high-speed cameras to capture dynamic events within a simulated brain, he will be able to look at rapid acceleration and deceleration to investigate what happens during such events. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 26, 2021 Category: International Medicine & Public Health Source Type: news

Retroviruses are re-writing the koala genome and causing cancer
(Leibniz Institute for Zoo and Wildlife Research (IZW)) Koalas are facing multiple environmental and health issues which threaten their survival. Along with habitat loss - accelerated by last year's devastating bush fires - domestic dog attacks and road accidents, they suffer from deadly chlamydial infections and extremely high frequency of cancer. An international team of scientists led by the Leibniz Institute for Zoo and Wildlife Research (Leibniz-IZW) now demonstrate that a retrovirus invading the koala germline explains the high frequency of koala cancer. The results are reported in the journalNature Communications. (...
Source: EurekAlert! - Medicine and Health - February 26, 2021 Category: International Medicine & Public Health Source Type: news

The key to proper muscle growth
(Max Delbr ü ck Center for Molecular Medicine in the Helmholtz Association) Three oscillating proteins cause new muscle cells to emerge from muscle stem cells in a balanced manner. In a paper being published in the journalNature Communications, a team led by MDC researcher Carmen Birchmeier explains in detail how this process works. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 26, 2021 Category: International Medicine & Public Health Source Type: news

MicroRNA testing of healthy kids could provide a window on future heart and kidney health
(The Mount Sinai Hospital / Mount Sinai School of Medicine) Molecules called microRNAs (miRNAs) that are measurable in urine have been identified by researchers at Mount Sinai as predictors of both heart and kidney health in children without disease. The epidemiological study of Mexican children was published in February in the journal Epigenomics. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 26, 2021 Category: International Medicine & Public Health Source Type: news

Not all " good " cholesterol is healthy
(IMIM (Hospital del Mar Medical Research Institute)) A study led by IMIM examines whether all so-called good cholesterol (HDL) particles have a cardiovascular protective effect. Traditionally, HDL cholesterol has been associated with a reduced risk of heart disease, but there are doubts as to whether all the particles have a protective effect. The work shows that people with large HDL particles have an increased risk of myocardial infarction, while only small HDL particles are actually associated with decreased risk. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 26, 2021 Category: International Medicine & Public Health Source Type: news

Curcumin for amyloidosis and lipid metabolism -- a novel insight
This study demonstrates that curcumin is a PPARα/γ dual activator and may affect expression levels of proteins involved in amyloid deposition and other metabolism functions in a complex manner. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 26, 2021 Category: International Medicine & Public Health Source Type: news

New open-source platform accelerates research into the treatment of heart arrhythmia's
(King's College London) An open-source platform, OpenEP co-developed by researchers from the School of Biomedical Engineering& Imaging Sciences at King's College London has been made available to advance research on atrial fibrillation, a condition characterised by an irregular (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 26, 2021 Category: International Medicine & Public Health Source Type: news

Using artificial intelligence to hunt for breast cancer
(BfR Federal Institute for Risk Assessment) Endocrine disruptors (EDs) are hormone-like substances that can have undesirable effects on health. For example, chemicals can increase the risk of breast cancer if they act in a manner similar to the female sex hormone oestrogen. Animal experiments are still required to detect the hormonal effects of chemical substances. A test has now been developed at the German Centre for the Protection of Laboratory Animals (Bf3R) that tests the effects of hormones on cultured human cells. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 26, 2021 Category: International Medicine & Public Health Source Type: news

Advantageous preparation of movement via independent control of muscle sensors
(Umea University) A number of brain areas change their activity before we execute a planned voluntary movement. A new study by Ume å University identifies a novel function of this preparatory neural activity, highlighting another mechanism the nervous system can use to achieve its goals. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 26, 2021 Category: International Medicine & Public Health Source Type: news

Multiple aspects of Coronavirus disease
(Bentham Science Publishers) This book presents the basic and advanced knowledge about the COVID-19 pandemic, organized into simple and easy-to-read chapters. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 26, 2021 Category: International Medicine & Public Health Source Type: news

Improving durability of dental structures
(Charit é - Universit ä tsmedizin Berlin) How can dental restorations - such as fillings and crowns - be made to last longer? A new research group centered at Charit é - Universit ä tsmedizin Berlin and Technische Universit ä t (TU) Berlin plans to address this topic by utilizing approaches from both materials science and dentistry. The aim is to gain a better understanding of the composition and structure of the material-tissue interfaces and the stresses exerted on them. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 26, 2021 Category: International Medicine & Public Health Source Type: news

Targeted spraying to prevent malaria in low-transmission setting halves cost of current practice
(University of the Witwatersrand) Furthermore, the targeted Indoor Residual Spraying (IRS) intervention was safe, less costly, and more cost-effective compared with standard 'blanket' IRS, meaning savings could potentially be reallocated to other malaria control and elimination activities. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 26, 2021 Category: International Medicine & Public Health Source Type: news

SARS-CoV-2 mutations in competition
(University of Bern) How dangerous are new mutations of the SARS-CoV-2 virus? An international team involving researchers from the Institute of Virology and Immunology (IVI) of the Federal Food Safety and Veterinary Office BLV and the University of Bern (Switzerland), the Centers for Disease Control and Prevention (USA), and the Friedrich-Loeffler Institute (Germany), has developed an approach that can accurately assess the transmissibility of new virus mutants. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 26, 2021 Category: International Medicine & Public Health Source Type: news

A missing protein promotes genetic instability in patients with Mulibrey syndrome
(University of Seville) The absence of the TRIM37 protein induces the formation of centrosomes in cells in turn favouring the development of tumours. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 26, 2021 Category: International Medicine & Public Health Source Type: news