What Are the Potential Benefits and Risks of Premasticated Foods?
Discussion Premastication is the prechewing of foods or medicines by another person before feeding to an infant. It is also used to pretaste or temperature test foods. It was a common practice for millennia, especially before modern food technology, as a way to transition an infant from a solely liquid based diet to a mixed diet mainly of solid food. Rates of premastication vary, with less developed countries having an increased incidence/prevalence (up to 50%) but it is not uncommon in developed countries (in the US 14% is reported). Saliva is also used to clean other people, treat cuts/itches or insect bites as well. Pla...
Source: PediatricEducation.org - November 14, 2022 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

Janssen to Highlight Latest Scientific Advances in Hematologic Diseases at ASH 2022 with Clinical and Real-World Data Across Innovative Pipeline and Distinguished Portfolio
RARITAN, N.J., November 3, 2022 – The Janssen Pharmaceutical Companies of Johnson & Johnson are committed to redefining treatment outcomes in the hematology setting and today announced that abstracts from more than 50 company-sponsored studies, plus more than 20 investigator-initiated studies, will be presented at the American Society of Hematology (ASH) Annual Meeting in New Orleans from December 10-13, 2022. Janssen’s commitment to advancing an innovative portfolio of therapies for healthcare professionals and patients is evidenced through more than 70 presentations that span clinical studies and r...
Source: Johnson and Johnson - November 3, 2022 Category: Pharmaceuticals Tags: Innovation Source Type: news

Cytomegalovirus is a Risk Factor for VTE in ANCA Vasculitis Cytomegalovirus is a Risk Factor for VTE in ANCA Vasculitis
Past exposure to cytomegalovirus has been identified as a risk factor for VTE development in patients with ANCA-associated vasculitis.Arthritis Research & Therapy (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - October 18, 2022 Category: Consumer Health News Tags: Rheumatology Journal Article Source Type: news

Congenital Cytomegalovirus Declined in Wake of COVID-19 Congenital Cytomegalovirus Declined in Wake of COVID-19
Prevalence for cCMV was highest among newborns of mothers aged 24 and younger, and in non-Hispanic Black mothers.MDedge News (Source: Medscape Infectious Diseases Headlines)
Source: Medscape Infectious Diseases Headlines - September 14, 2022 Category: Infectious Diseases Tags: Pediatrics News Source Type: news

What are Potential Problems with Placental Abnormalities?
Discussion “The placenta is a unique organ that sits at the interface of, and facilitates nearly all interactions between, maternal and fetal physiology. It is the sole source of oxygen and nutrition for the fetus, and provides a protective barrier against external insults. The placenta is also a highly adaptable organ that is capable of showing a wide range of pathological changes in response to various maternal and fetal factors and stressors.” The placenta has 3 layers: the amnion (fetal side), the chorion, and decidua (maternal side). In addition to making observations about the maternal and fetal sides, co...
Source: PediatricEducation.org - June 27, 2022 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

CMV Seropositivity Tied to Cortical Surface Area in Schizophrenia
FRIDAY, June 17, 2022 -- For adults with schizophrenia spectrum disorders, previous cytomegalovirus (CMV) infection is associated with smaller total cortical surface area, according to a study recently published in Schizophrenia Bulletin. Dimitrios... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - June 17, 2022 Category: Pharmaceuticals Source Type: news

Longer-term Data from CARTITUDE-1 Study Demonstrate Continued Deep and Durable Responses to CARVYKTI ™ (ciltacabtagene autoleucel) in Heavily Pretreated Patients with Relapsed or Refractory Multiple Myeloma
CHICAGO, ILLINOIS, June 4, 2022 – – The Janssen Pharmaceutical Companies of Johnson & Johnson announced today updated results from the Phase 1b/2 CARTITUDE-1 study evaluating the efficacy and safety of CARVYKTI™ (ciltacabtagene autoleucel; cilta-cel), a B-cell maturation antigen (BCMA)-directed chimeric antigen receptor T-cell (CAR-T) therapy. The study included patients with relapsed or refractory multiple myeloma (RRMM) who had received >3 lines of therapy including a proteasome inhibitor (PI), an anti-CD38 monoclonal antibody and an immunomodulatory agent (IMiD) or were double refractory to an IMiD and PI a...
Source: Johnson and Johnson - June 4, 2022 Category: Pharmaceuticals Tags: Innovation Source Type: news

Janssen to Highlight Science, Innovation and Advances in Robust Oncology Portfolio and Pipeline Through More Than 60 Data Presentations at ASCO and EHA
RARITAN, N.J., May 31, 2022 — The Janssen Pharmaceutical Companies of Johnson & Johnson announced today that new research and data from its robust oncology portfolio and pipeline of investigational therapies will be presented at the 2022 American Society of Clinical Oncology (ASCO) Annual Meeting, taking place June 3-7 in Chicago, and the European Hematology Association (EHA) 2022 Congress taking place in Vienna, Austria, June 9-12. More than 60 presentations from company-sponsored studies across the two congresses, including 14 oral presentations, will feature new data and updates for both approved and investigation...
Source: Johnson and Johnson - May 31, 2022 Category: Pharmaceuticals Source Type: news

Man given a PIG's heart in world-first transplant may have died as the organ was infected
DAVID BENNETT was the first person in the world to receive a pig's heart transplant. Sadly, the 57-year-old died on March 8 merely MONTHS after the surgery. An expert now thinks that the transplant might have been infected with porcine cytomegalovirus. (Source: Daily Express - Health)
Source: Daily Express - Health - May 6, 2022 Category: Consumer Health News Source Type: news

Signs of an Animal Virus Discovered in Man Who Received a Pig ’s Heart
The patient showed no sign of rejecting the genetically modified organ, but suffered numerous complications before dying. (Source: NYT Health)
Source: NYT Health - May 6, 2022 Category: Consumer Health News Authors: Roni Caryn Rabin Tags: your-feed-science Transplants Surgery and Surgeons Pigs Genetic Engineering Cytomegalovirus University of Maryland Source Type: news

An Animal Virus Infected the Man Who Received a Pig ’s Heart
The patient showed no sign of rejecting the genetically modified organ, but may have died from the viral infection, his surgeon said. (Source: NYT Health)
Source: NYT Health - May 5, 2022 Category: Consumer Health News Authors: Roni Caryn Rabin Tags: your-feed-science Transplants Surgery and Surgeons Pigs Genetic Engineering Cytomegalovirus University of Maryland Source Type: news

U.S. FDA Approves CARVYKTI ™ (ciltacabtagene autoleucel), Janssen’s First Cell Therapy, a BCMA-Directed CAR-T Immunotherapy for the Treatment of Patients with Relapsed or Refractory Multiple Myeloma
HORSHAM, Pa., February 28, 2022 – The Janssen Pharmaceutical Companies of Johnson & Johnson announced today the U.S. Food and Drug Administration (FDA) has approved CARVYKTI™ (ciltacabtagene autoleucel; cilta-cel) for the treatment of adults with relapsed or refractory multiple myeloma (RRMM) after four or more prior lines of therapy, including a proteasome inhibitor, an immunomodulatory agent, and an anti-CD38 monoclonal antibody.1 The approval is based on data from the pivotal CARTITUDE-1 study, which included patients who had received a median of six prior treatment regimens (range, 3-18), and had previously rec...
Source: Johnson and Johnson - March 1, 2022 Category: Pharmaceuticals Tags: Innovation Source Type: news

What Causes Rectal Prolapse?
Discussion Rectal prolapse is defined as a herniation of the rectum through the anal verge. In children it is also usually mucosal prolapse and not full thickness. Partial or mucosal prolapse usually is seen as radial folds occurring 1 – 2.5 cm from the anal verge. Full thickness will protrude more than 5 cm. It affects genders equally and occurs most commonly in children under age 4. This is due to vertical course and low position of the anus, looser supporting tissues and less muscular support. These children are more likely to have prolapse but are less likely to have it recur. After age 4 the rectum takes the adu...
Source: PediatricEducation.org - February 28, 2022 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

FDA Approves First Drug for Treatment of Resistant CMV FDA Approves First Drug for Treatment of Resistant CMV
Transplant patients are particularly vulnerable to cytomegalovirus (CMV) infection, which can lead to organ loss or death.FDA Approvals (Source: Medscape Infectious Diseases Headlines)
Source: Medscape Infectious Diseases Headlines - November 24, 2021 Category: Infectious Diseases Tags: Transplantation News Alert Source Type: news

FDA Approves Livtencity (maribavir) for Post-Transplant Cytomegalovirus (CMV) Infection/Disease
- In the Phase 3 SOLSTICE study, more than twice the proportion of adult transplant recipients with refractory or resistant (R/R) CMV infection/disease achieved confirmed CMV DNA level<LLOQ at Week 8 with Livtencity (56%; n=131/235), compared to... (Source: Drugs.com - New Drug Approvals)
Source: Drugs.com - New Drug Approvals - November 23, 2021 Category: Drugs & Pharmacology Source Type: news