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Post-doctoral position at Laboratory of Central and Peripheral Mechanisms of Neurodegeneration, Strasbourg University
A post-doctoral position is available at the Inserm Laboratory of Central and Peripheral Mechanisms of Neurodegeneration (UMR-S1118) team, to study the role of the hypothalamus in amyotrophic lateral sclerosis.The team has previously identified structural and functional deficits in the hypothalamus of ALS mouse models and patients (Vercruysse et al, Brain, 2016; Gorges, Vercruysse et al., JNNP, 2017; for review see Vercruysse et al, Frontiers, 2018) and identified alterations in selected neuronal types in the hypothalamus of mouse models. They now aim at using mouse genetics, combined with pharmacogenetics,&nb...
Source: Society for Endocrinology - May 16, 2018 Category: Endocrinology Source Type: news

FDA Lays the Smackdown on Illegal Stem Cell Clinics
FDA is cracking down on stem cell clinics that market unapproved products and don't meet good manufacturing practice requirements. On behalf of the agency, the Department of Justice filed two complaints in federal court this week seeking permanent injunctions against a Florida-based clinic and a California-based clinic.  “Cell-based regenerative medicine holds significant medical opportunity, but we’ve also seen some bad actors leverage the scientific promise of this field to peddle unapproved treatments that put patients’ health at risk. In some instances, patients have suffered serious and per...
Source: MDDI - May 10, 2018 Category: Medical Devices Authors: Amanda Pedersen Tags: Regulatory and Compliance Source Type: news

Companies to use data in battle against Parkinson's, Alzheimer's, ALS
Morrisville-based contract research organization Worldwide Clinical Trials and Roivant-backed health care technology company Datavant are partnering to take on neurodegenerative diseases. Some of the most common neurodegenerative diseases include Parkinson's, Alzheimer's, Huntington's and amyotrophic lateral sclerosis, or ALS. According to Worldwide and Datavant, the most common neurodegenerative diseases cost the U.S. close to $800 billion annually.  Through the new partnership, Worldwide and… (Source: bizjournals.com Health Care:Physician Practices headlines)
Source: bizjournals.com Health Care:Physician Practices headlines - May 8, 2018 Category: American Health Authors: Jennifer Henderson Source Type: news

Neuraltus Pharmaceuticals Reports Results from Phase 2 NP001 Study in Amyotrophic Lateral Sclerosis (ALS)
SAN BRUNO, Calif. and LOS ANGELES, April 26, 2018 -- (Healthcare Sales & Marketing Network) -- Neuraltus Pharmaceuticals, Inc., a privately-held pharmaceutical company dedicated to developing innovative therapeutics for neurodegenerative diseases, today a... Biopharmaceuticals, Neurology Neuraltus Pharmaceuticals, Amyotrophic Lateral Sclerosis (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - April 26, 2018 Category: Pharmaceuticals Source Type: news

Linear Link for Physical Activity, Amyotrophic Lateral Sclerosis
TUESDAY, April 24, 2018 -- There is a linear correlation for physical activity (PA) with amyotrophic lateral sclerosis (ALS), according to a study published online April 23 in the Journal of Neurology, Neurosurgery& Psychiatry. Anne E. Visser,... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - April 24, 2018 Category: Pharmaceuticals Source Type: news

Extreme Exercisers May Have Higher Odds for ALS
MONDAY, April 23, 2018 -- Fitness buffs who push themselves to the limit during workouts might slightly increase their risk of developing amyotrophic lateral sclerosis (ALS), a new study suggests. The same may hold true for working stiffs whose jobs... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - April 23, 2018 Category: General Medicine Source Type: news

Two genes associated with ALS risk identified
Two previously unrecognized genetic risks that are significantly associated with amyotrophic lateral sclerosis have been identified by researchers. (Source: Health News - UPI.com)
Source: Health News - UPI.com - April 10, 2018 Category: Consumer Health News Source Type: news

UCSF researcher identifies risk genes for ALS
(University of California - San Francisco) The largest analysis to date of genetic data in amyotrophic lateral sclerosis (ALS) -- the muscle-crippling neurodegenerative disease that afflicted the late astrophysicist Stephen Hawking and cut short the career of iconic Yankee baseball slugger Lou Gehrig -- has identified two previously unrecognized genetic risks that are significantly associated with the disease. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - April 9, 2018 Category: Infectious Diseases Source Type: news

ALS, rare dementia share genetic link
(Washington University School of Medicine) Studying data from more than 125,000 individuals, an international team of researchers led by scientists at Washington University School of Medicine in St. Louis has identified genetic links between amyotrophic lateral sclerosis (ALS) and frontotemporal dementia. The link between the seemingly unrelated disorders suggests that some drugs developed to treat ALS also may work against frontotemporal dementia and vice versa. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - April 9, 2018 Category: International Medicine & Public Health Source Type: news

Brain's tiniest blood vessels trigger spinal motor neurons to develop
(Cedars-Sinai Medical Center) A new study has revealed that the human brain's tiniest blood vessels can activate genes known to trigger spinal motor neurons, prompting the neurons to grow during early development. The findings could provide insights into how amyotrophic lateral sclerosis (ALS) and other neurodegenerative disorders may develop. To make the discovery, investigators successfully re-created living tissues of the blood vessels and the spinal motor neurons -- which control muscles -- outside the body to show how they interact. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 23, 2018 Category: International Medicine & Public Health Source Type: news

BrainStorm Appoints Two Leading Thought Leaders in the Fields of Neuroscience and Regenerative Medicine to its Scientific Advisory Board
HACKENSACK, N.J. and PETACH TIKVAH, Israel, March 21, 2018 -- (Healthcare Sales & Marketing Network) -- BrainStorm Cell Therapeutics Inc. (NASDAQ: BCLI), a leading developer of adult stem cell therapies for neurodegenerative diseases, today announced the ... Regenerative Medicine, Neurology, Personnel BrainStorm Cell Therapeutics, NurOwn , stem cell, amyotrophic lateral sclerosis (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - March 21, 2018 Category: Pharmaceuticals Source Type: news

NIH-supported international team confirms new genetic mutation link to ALS
(NIH/National Institute on Aging) Kinesin family member 5A (KIF5A), a gene previously linked to two rare neurodegenerative disorders, has been definitively connected to amyotrophic lateral sclerosis (ALS) by an NIH-supported international team from several of the world's top ALS research labs. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - March 21, 2018 Category: International Medicine & Public Health Source Type: news

Peninsula biotech lands $150 million deal to tackle brain diseases
Alzheimer's disease and amyotrophic lateral sclerosis, or Lou Gehrig's disease, are two potential deals of a multi-year deal between a Peninsula company and Celgene. (Source: bizjournals.com Health Care:Pharmaceuticals headlines)
Source: bizjournals.com Health Care:Pharmaceuticals headlines - March 20, 2018 Category: Pharmaceuticals Authors: Ron Leuty Source Type: news

Peninsula biotech lands $150 million deal to tackle brain diseases
Alzheimer's disease and amyotrophic lateral sclerosis, or Lou Gehrig's disease, are two potential deals of a multi-year deal between a Peninsula company and Celgene. (Source: bizjournals.com Health Care:Biotechnology headlines)
Source: bizjournals.com Health Care:Biotechnology headlines - March 20, 2018 Category: Biotechnology Authors: Ron Leuty Source Type: news

Riluzole Appears to Extend ALS Survival by Prolonging the Last Stage Riluzole Appears to Extend ALS Survival by Prolonging the Last Stage
Riluzole appears to extend survival in patients with amyotrophic lateral sclerosis (ALS) by prolonging the last clinical stage before death, according to a retrospective analysis.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - March 20, 2018 Category: Consumer Health News Tags: Neurology & Neurosurgery News Source Type: news

How Stephen Hawking Helped Redefine Humanity ’s Existence
During the fall of my sophomore year at Harvard, a group of my fellow physics majors were excitedly discussing a rumor they’d just heard: Stephen Hawking was coming to give the prestigious Loeb Lectures. I played along with their excitement, but truth be told, I didn’t know who Stephen Hawking was. This was the early 1980s, well before A Brief History of Time, so to all but the most physics-savvy of people, Hawking had yet to become Hawking. The rumor was true, and a few weeks later the physics-savvy crowd turned out in force, packing the largest hall to hear Hawking discuss relativity and the origin of the uni...
Source: TIME: Science - March 15, 2018 Category: Science Authors: Brian Greene Tags: Uncategorized onetime remembrance Source Type: news

How Stephen Hawking Helped Redefine the Rules of Reality
During the fall of my sophomore year at Harvard, a group of my fellow physics majors were excitedly discussing a rumor they’d just heard: Stephen Hawking was coming to give the prestigious Loeb Lectures. I played along with their excitement, but truth be told, I didn’t know who Stephen Hawking was. This was the early 1980s, well before A Brief History of Time, so to all but the most physics-savvy of people, Hawking had yet to become Hawking. The rumor was true, and a few weeks later the physics-savvy crowd turned out in force, packing the largest hall to hear Hawking discuss relativity and the origin of the uni...
Source: TIME: Science - March 15, 2018 Category: Science Authors: Brian Greene Tags: Uncategorized onetime remembrance Source Type: news

Missouri researcher wins $50,000 Sheila Essey Award: An award for ALS research
(American Academy of Neurology) LOS ANGELES - The American Academy of Neurology, The ALS Association and the American Brain Foundation are awarding the 2018 Sheila Essey Award to Timothy M. Miller, MD, PhD, from the Washington University School of Medicine in St. Louis, Mo., and a member of the American Academy of Neurology. The award recognizes significant research contributions in the search for the causes, prevention and cure for amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 15, 2018 Category: International Medicine & Public Health Source Type: news

The Guardian view on Stephen Hawking: the mind of God | Editorial
The death of a brilliant and complex scientist will mean we are all poorer because his mind will no longer roam the multiversesStephen Hawking was a brilliant, complex man and scientist. Diagnosed at 21 with amyotrophic lateral sclerosis, he had been expected to live a few more years. Hawkinglasted another 55. He made his name as a young Cambridge cosmologist withbreakthroughs as awesome as anything religion offers: proving that big bang theory must hold true and elucidating the link between gravity and quantum mechanics. From his wheelchair, Hawking ’s mind roamed the multiverses. It was his 1988 bestseller A Brief ...
Source: Guardian Unlimited Science - March 14, 2018 Category: Science Authors: Editorial Tags: Stephen Hawking Science NHS Society European Union World news Motor neurone disease Black holes Donald Trump Source Type: news

Stephen Hawking May Have Been the Longest-Living ALS Survivor. Here ’s What We Know
The world lost one of its most brilliant scientific minds Wednesday, when legendary physicist Stephen Hawking died at age 76. Hawking’s cause of death was likely amyotrophic lateral sclerosis, or ALS, a neurodegenerative disease that wears away at nerve and muscle function over time. He was first diagnosed with ALS more than five decades ago, at age 21, and was initially given just a few years to live — making the very nature of his long, illustrious career as much of a scientific marvel as the theories and discoveries it yielded. Here’s what to know about ALS, and what may have allowed Hawking to beat th...
Source: TIME: Health - March 14, 2018 Category: Consumer Health News Authors: Jamie Ducharme Tags: Uncategorized healthytime medicine onetime Source Type: news

House Rejects GOP Bill Giving Terminally Ill Patients the ‘Right to Try’ Experimental Treatment
(WASHINGTON) — The House rejected legislation Tuesday easing how experimental drugs are provided to people with terminal illnesses, as Democrats calling the bill risky and misleading overcame support from President Donald Trump and emotional arguments by Republican lawmakers and ailing constituents. The vote for the measure was 259-140, but that fell short of the two-thirds majority the GOP needed to prevail under special procedures. Since the Senate approved similar legislation last August, Republicans could revisit the legislation under rules that would require only a simple majority for passage, perhaps after rewo...
Source: TIME: Health - March 14, 2018 Category: Consumer Health News Authors: Alan Fram / AP Tags: Uncategorized APH Congress healthytime onetime Source Type: news

Famed Physicist Stephen Hawking Has Died at the Age of 76
(LONDON) — Stephen Hawking, whose brilliant mind ranged across time and space though his body was paralyzed by disease, died early Wednesday, a University of Cambridge spokesman said. He was 76 years old. Hawking died peacefully at his home in Cambridge, England. The best-known theoretical physicist of his time, Hawking wrote so lucidly of the mysteries of space, time and black holes that his book, “A Brief History of Time,” became an international best seller, making him one of science’s biggest celebrities since Albert Einstein. “He was a great scientist and an extraordinary man whose work a...
Source: TIME: Science - March 14, 2018 Category: Science Authors: Robert Barr / AP Tags: Uncategorized onetime overnight remembrance Source Type: news

WATCH: Watch 'GMA' anchors take ALS Pepper Challenge
The viral social media campaign is raising awareness for amyotrophic lateral sclerosis (ALS). (Source: ABC News: Health)
Source: ABC News: Health - March 13, 2018 Category: Consumer Health News Tags: GMA Source Type: news

CRISPR helps find new genetic suspects behind ALS/FTD
(NIH/National Institute of Neurological Disorders and Stroke) NIH-funded researchers used the gene editing tool CRISPR to rapidly identify genes in the human genome that might modify the severity of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) caused by mutations in a gene called C9orf72. The results of the search uncovered a new set of genes that may hasten neuron death during the disease. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 12, 2018 Category: International Medicine & Public Health Source Type: news

BrainStorm Announces Operational Highlights and Financial Results for the Year Ended December 31, 2017
Conference Call and Webcast @ 8:30 a.m. Eastern Time Today NEW YORK and PETACH TIKVAH, Israel, March 8, 2018 -- (Healthcare Sales & Marketing Network) -- BrainStorm Cell Therapeutics Inc. (NASDAQ: BCLI), a leading developer of adult stem cell technolog... Regenerative Medicine, Neurology BrainStorm Cell Therapeutics, NurOwn , stem cell, amyotrophic lateral sclerosis (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - March 8, 2018 Category: Pharmaceuticals Source Type: news

Scientists discover a key function of als-linked protein
(Johns Hopkins University Bloomberg School of Public Health) The protein FUS, whose mutation or disruption causes many cases of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), works as a central component of one of the most important regulatory systems in cells, according to a new study in Molecular Cell from scientists at Johns Hopkins Bloomberg School of Public Health. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 8, 2018 Category: International Medicine & Public Health Source Type: news

Supply bottleneck impairs nerve function
(University of W ü rzburg) Impaired transport processes in neurons contribute to diseases such as amyotrophic lateral sclerosis (AML). W ü rzburg scientists have now identified key actors in these processes. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 8, 2018 Category: International Medicine & Public Health Source Type: news

Syracuse U. researchers close to understanding 'disease mechanisms' of ALS
(Syracuse University) Syracuse University researchers are making strides in understanding the disease mechanism of amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 8, 2018 Category: International Medicine & Public Health Source Type: news

The Neuro and Thermo Fisher Scientific Partner to fight neurodegenerative disease
(McGill University) The Montreal Neurological Institute (The Neuro) of McGill University, a world-leading institution focused on brain research and advanced patient care, and Thermo Fisher Scientific, the world leader in serving science, today announce an agreement designed to accelerate the understanding of neurological disease by focusing on about 30 proteins associated with Parkinson's disease, amyotrophic lateral sclerosis (ALS), hereditary spastic paraplegias, epileptic encephalopathies and ataxias, which are all devastating brain diseases. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 5, 2018 Category: International Medicine & Public Health Source Type: news

Retinol-binding Protein 4 Linked to ALS Risk, Prognosis Retinol-binding Protein 4 Linked to ALS Risk, Prognosis
Higher serum concentrations of retinol-binding protein 4 (RBP4) are associated with reduced risk and better prognosis of amyotrophic lateral sclerosis (ALS), according to results from the ALS Registry Study Group.Reuters Health Information (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 2, 2018 Category: Consumer Health News Tags: Neurology & Neurosurgery News Source Type: news

Diesel Exhaust Linked to ALS Diesel Exhaust Linked to ALS
New research shows that men exposed on the job to diesel exhaust have a higher risk for developing amyotrophic lateral sclerosis.Medscape Medical News (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 1, 2018 Category: Consumer Health News Tags: Neurology & Neurosurgery News Source Type: news

Diesel Exhaust Might Raise Truckers' Odds for ALS
TUESDAY, Feb. 27, 2018 -- Truckers and others who are routinely exposed to diesel fumes while on the job might face a greater chance of developing amyotrophic lateral sclerosis (ALS), a new study suggests. The increased risk hit a high of 40... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - February 27, 2018 Category: General Medicine Source Type: news

Catherine Wolf, 70, Dies; Studied How People and Computers Interact
A leader in IBM ’ s development of a speech-recognition system, she relied on her laptop to communicate after Lou Gehrig ’ s disease left her paralyzed. (Source: NYT Health)
Source: NYT Health - February 22, 2018 Category: Consumer Health News Authors: RICHARD SANDOMIR Tags: Wolf, Catherine Deaths (Obituaries) Computers and the Internet Voice Recognition Systems Amyotrophic Lateral Sclerosis International Business Machines Corporation Source Type: news

Prevalence of Amyotrophic Lateral Sclerosis — United States, 2014
(Source: CDC Morbidity and Mortality Weekly Report)
Source: CDC Morbidity and Mortality Weekly Report - February 22, 2018 Category: American Health Source Type: news

BrainStorm Cell Therapeutics Appoints Senior Kite Executive, Anthony Polverino, Ph.D., to Board of Directors
HACKENSACK, N.J. and PETACH TIKVAH, Israel, Feb. 5, 2018 -- (Healthcare Sales & Marketing Network) -- BrainStorm Cell Therapeutics Inc. (NASDAQ: BCLI), a leading developer of adult stem cell therapeutics for neurodegenerative diseases, announced today the... Biopharmaceuticals, Neurology, Personnel BrainStorm Cell Therapeutics, NurOwn , stem cell, amyotrophic lateral sclerosis (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - February 5, 2018 Category: Pharmaceuticals Source Type: news

Low muscle strength identified as early risk factor for ALS
(University of Gothenburg) Low muscle strength during the later teen years has been identified as a risk factor for much later onset of the neurological disease known as ALS, or amyotrophic lateral sclerosis. A study at Sahlgrenska Academy published in the Journal of Neurology also links low blood counts at a young age to ALS. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 2, 2018 Category: International Medicine & Public Health Source Type: news

Pro Football Players May Die Earlier Than Their Peers, Study Says
The professional football industry has been rocked by plenty of bad press in recent years, from domestic violence charges to studies linking the sport to chronic brain injury. Now, just ahead of this weekend’s Super Bowl, a new study casts another shadow over the game: Career players in the National Football League (NFL) have slightly higher rates of early death than their peers who didn’t play professionally, according to a report published in JAMA. The difference in mortality rate between NFL players and non-NFL players was not statistically significant, meaning that the total number of deaths in the study wa...
Source: TIME: Health - February 1, 2018 Category: Consumer Health News Authors: Amanda MacMillan Tags: Uncategorized chronic traumatic encephalopathy concussions cte football players football cte study football injuries football safety healthytime is football dangerous is football safe onetime Research why is football dangerous Source Type: news

Arizona State to grow human neurons, test treatments for neurodegenerative diseases
(Arizona State University) Lab-grown human neurons will be used to develop and test treatments for devastating neurodegenerative diseases, particularly Alzheimer's disease, Parkinson's disease and Amyotrophic lateral sclerosis. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - January 23, 2018 Category: International Medicine & Public Health Source Type: news

ALS Patients Value What They Learn From Genetic Testing ALS Patients Value What They Learn From Genetic Testing
Patients with amyotrophic lateral sclerosis (ALS) find value in genetic testing for the disease, whether or not they have a family history of the condition, according to findings from a survey conducted by U.S. researchers.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - January 17, 2018 Category: Consumer Health News Tags: Neurology & Neurosurgery News Source Type: news

Cells from Diseased Donors
Focus on Neuro Diseases We now have the capability to provide cells of the central and peripheral nervous system from donors with Neuro diseases. These include cells from donors with ALS, AD, PD, and Brain Cancer Donors, to name a few.We have provided cells to virtually all the large Pharmas and many small and mid-size Bio-techs. We have worked with Novartis to gain 21-CFR compliance for cells that they are using for their eye diseases drug discovery programs.I am at your “beck and call” should you have interested in exploring specific capabilities further. You can e-mail or call me at 612-801-1007 (Source: Neuromics)
Source: Neuromics - January 15, 2018 Category: Neuroscience Tags: 3-D Cell based Assays ALS Alzheimer ' s Disease Amyotrophic Lateral Sclerosis glioblastomas Parkinson Source Type: news

Cellular traffic jam seen in ALS/FTD -- Supports drug strategy
(Emory Health Sciences) A cellular traffic jam appears to affect neurons in most forms of ALS (amyotrophic lateral sclerosis), Emory/Mayo researchers have shown. The findings suggest that a drug strategy aimed at easing the traffic jam may be generalizable to sporadic and at least some familial types of ALS and FTD (frontotemporal dementia). (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - January 8, 2018 Category: International Medicine & Public Health Source Type: news

Understanding the molecular mechanisms of ALS
(Hokkaido University) Scientists have revealed more details of the molecular mechanism behind neuronal cell death in amyotrophic lateral sclerosis (ALS), a step forward to find ways to control progression of the disease. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - December 26, 2017 Category: International Medicine & Public Health Source Type: news

CDC Grand Rounds: National Amyotrophic Lateral Sclerosis (ALS) Registry Impact, Challenges, and Future Directions
(Source: CDC Morbidity and Mortality Weekly Report)
Source: CDC Morbidity and Mortality Weekly Report - December 21, 2017 Category: American Health Source Type: news

Disarm Therapeutics Appoints Peter Keller Chief Business Officer
CAMBRIDGE, Mass., Dec. 19, 2017 -- (Healthcare Sales & Marketing Network) -- Disarm Therapeutics, a biotechnology company creating a new class of disease-modifying therapeutics for patients with axonal degeneration, a central driver of neurological diseas... Biopharmaceuticals, Neurology, Personnel Disarm Therapeutics, SARM1, multiple sclerosis, amyotrophic lateral sclerosis (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - December 19, 2017 Category: Pharmaceuticals Source Type: news

Upsized $300M biotech IPO could be huge — or another flop in Alzheimer’s and ALS
There's a lot riding on Denali Therapeutics Inc.'s upsized, mountainous $303 million IPO — and it goes beyond the eye-popping fundraise. To be sure, investors are watching the South San Francisco developer of drugs for Alzheimer's disease, Parkinson's disease and amyotrophic lateral sclerosis, or ALS — in a Securities and Exchange Commission filing Thursday morning, the 125-employe e company boosted the shares available in the IPO from 9.58 million to 15.97 million. At the top of its $17 to… (Source: bizjournals.com Health Care:Physician Practices headlines)
Source: bizjournals.com Health Care:Physician Practices headlines - December 7, 2017 Category: American Health Authors: Ron Leuty Source Type: news

Why this $300 million biotech IPO could be huge — or another flop in Alzheimer’s and ALS
There's a lot riding on Denali Therapeutics Inc.'s upsized, mountainous $303 million IPO — and it goes beyond the eye-popping fundraise. To be sure, investors are watching the South San Francisco developer of drugs for Alzheimer's disease, Parkinson's disease and amyotrophic lateral sclerosis, or ALS — in a Securities and Exchange Commission filing Thursday morning, the 125-employe e company boosted the shares available in the IPO from 9.58 million to 15.97 million. At the top of its $17 to… (Source: bizjournals.com Health Care:Pharmaceuticals headlines)
Source: bizjournals.com Health Care:Pharmaceuticals headlines - December 7, 2017 Category: Pharmaceuticals Authors: Ron Leuty Source Type: news

The MNI forms promising Open Science partnership with Takeda
(McGill University) A unique industry-academia partnership will increase the rate at which promising drug compounds can be tested as potential treatments for amyotrophic lateral sclerosis (ALS), a disease with no known cure that affects 200,000 people worldwide. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - December 5, 2017 Category: International Medicine & Public Health Source Type: news

Mitsubishi Tanabe Pharma America Announces Addition of RADICAVA(R) (edaravone) to U.S. Department of Veterans Affairs National Formulary
JERSEY CITY, N.J., Nov. 30, 2017 -- (Healthcare Sales & Marketing Network) -- Mitsubishi Tanabe Pharma America, Inc. (MTPA) announced today that the U.S. Department of Veterans Affairs (VA) has added RADICAVA® (edaravone) to its National Formulary (VA... Biopharmaceuticals, Neurology, Reimbursement Mitsubishi Tanabe Pharma, RADICAVA, edaravone, amyotrophic lateral sclerosis (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - November 30, 2017 Category: Pharmaceuticals Source Type: news

Barrow researchers validate five new genes responsible for ALS
(St. Joseph's Hospital and Medical Center) Barrow Neurological Institute researchers have completed additional experiments that validate the identification of five new genes linked to Amyotrophic Lateral Sclerosis (ALS) -- also known as Lou Gehrig's disease. The new study results, validated through five different methods, were published in a full length manuscript in Acta Neuropathologica, validating earlier findings in the project. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - November 30, 2017 Category: Biology Source Type: news

Swinging at Lou Gehrig's disease, Peninsula drug maker strikes out
After spending "hundreds of millions" of dollars over eight years on an experimental drug for people with amyotrophic lateral sclerosis, or ALS, a South San Francisco company's late-stage trial came up short. (Source: bizjournals.com Health Care:Biotechnology headlines)
Source: bizjournals.com Health Care:Biotechnology headlines - November 21, 2017 Category: Biotechnology Authors: Ron Leuty Source Type: news