Armpit Swelling After COVID-19 Vaccine May Mimic Breast Cancer Armpit Swelling After COVID-19 Vaccine May Mimic Breast Cancer
Some women have experienced axillary node swelling after receiving the Pzifer-BioNTech or Moderna COVID-19 vaccines. The swelling mimics symptoms of breast cancer.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - February 25, 2021 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

US Cancer Drug Approvals Ensure Access but Not Value US Cancer Drug Approvals Ensure Access but Not Value
Many cancer drugs come to market in the US at unaffordable prices and uncertainty about benefits and harms; their uptake is often delayed elsewhere.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - February 25, 2021 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

FDA Places Clinical Hold on Sickle Cell Gene Therapy FDA Places Clinical Hold on Sickle Cell Gene Therapy
FDA placed a clinical hold on two gene therapy clinical trials for sickle cell disease after two patients developed blood diseases.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - February 25, 2021 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

FDA Approves Cemiplimab-rwlc for NSCLC With PD-L1 Expression FDA Approves Cemiplimab-rwlc for NSCLC With PD-L1 Expression
The FDA has approved cemiplimab-rwlc as monotherapy for first-line treatment of advanced non –small cell lung cancer (NSCLC) with PD-L1 expression of at least 50%.FDA Approvals (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - February 24, 2021 Category: Cancer & Oncology Tags: Hematology-Oncology News Alert Source Type: news

ASCO Announces New Advanced Liver Cancer Guidelines ASCO Announces New Advanced Liver Cancer Guidelines
New guidelines from the American Society of Clinical Oncology were released to address the treatment of advanced hepatocellular carcinoma.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - February 24, 2021 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

What Drives an Exceptional Response to Cancer Treatment? What Drives an Exceptional Response to Cancer Treatment?
Dr David Kerr implores us to cherish the'unusual patients,'as they may be key to better understanding those cancers that exhibit exceptional responses to treatment.Medscape Oncology (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - February 23, 2021 Category: Cancer & Oncology Tags: Hematology-Oncology Commentary Source Type: news

CAR T-cell Products Shine, Reveal New Insights CAR T-cell Products Shine, Reveal New Insights
The 12-month response and progression-free survival rates in 152 real-world patients treated with tisagenlecleucel (Kymriah) for an approved indication were 48.4% and 26.4%, respectively.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - February 22, 2021 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

How Has the Pandemic Affected Rural and Urban Cancer Patients? How Has the Pandemic Affected Rural and Urban Cancer Patients?
Research has shown that, compared with their urban counterparts, rural cancer patients have higher cancer-related mortality and other negative treatment outcomes.Medscape Oncology (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - February 22, 2021 Category: Cancer & Oncology Tags: Hematology-Oncology Commentary Source Type: news

Oncologist Burnout High; Happiness Outside Work Takes a Plunge Oncologist Burnout High; Happiness Outside Work Takes a Plunge
The latest Medscape survey shows that oncologists already had high levels of burn out and depression, but the pandemic has caused happiness levels to plunge.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - February 22, 2021 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

Routine COVID-19 Screening Unnecessary for Cancer Outpatients Routine COVID-19 Screening Unnecessary for Cancer Outpatients
There were no significant differences in COVID-19 outcomes between cases caught by routine screening and screening based on COVID symptoms among cancer outpatients treated at Mayo Clinic facilities.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - February 22, 2021 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

Novel ddPCR Assay Precisely Measures CAR T-cells After Infusion Novel ddPCR Assay Precisely Measures CAR T-cells After Infusion
A novel quantitative assay used with flow cytometry precisely measures CAR T-cell engraftment and in vivo expansion to predict patient outcomes after CAR T-cell infusion, according to researchers.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - February 22, 2021 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

Steroid Complications in GVHD Common, Boost Costs of Care Steroid Complications in GVHD Common, Boost Costs of Care
Among 689 patients with a diagnosis of graft versus host disease following HSCT who received steroids, 97% had at least one steroid-related complication, according to a retrospective database analysis.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - February 22, 2021 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

Quick MRI Scan for Routine Prostate Cancer Screening? Quick MRI Scan for Routine Prostate Cancer Screening?
New results suggest that a quick and contrast-free MRI scan for routine screening could have a better risk –benefit ratio than the current PSA blood test.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - February 22, 2021 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

Cheat Code: Cracking Cancer's Evolution to Help Defeat It Cheat Code: Cracking Cancer's Evolution to Help Defeat It
Cancer cells evolved to outsmart our bodies, but researchers are turning the tables on this disease via adaptive treatment strategies.Medscape Oncology (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - February 19, 2021 Category: Cancer & Oncology Tags: Hematology-Oncology Article Source Type: news

Near-Infrared Imaging for Tumors Deep in Tissue, Such as GISTs Near-Infrared Imaging for Tumors Deep in Tissue, Such as GISTs
Near-infrared hyperspectral imaging combined with machine learning may hold promise for identifying deep-tissue gastrointestinal stromal tumors (GISTs).Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - February 18, 2021 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

Using AI to Maximize the Value of Radiographic Images Using AI to Maximize the Value of Radiographic Images
Artificial intelligence (AI) is expected to one day affect the entire continuum of cancer care – from screening and risk prediction to diagnosis, risk stratification, treatment selection, and follow-up.Medscape Radiology (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - February 18, 2021 Category: Cancer & Oncology Tags: Radiology Commentary Source Type: news

Chronic GVHD Therapies Offer Hope for Treating Refractory Disease Chronic GVHD Therapies Offer Hope for Treating Refractory Disease
Patients with chronic graft-versus-host disease (GVHD) may require prolonged treatment with multiple lines of therapy, said a hematologist and transplant researcher.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - February 18, 2021 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

Combo Shows'Impressive' Survival Results in First-Line RCC Combo Shows'Impressive' Survival Results in First-Line RCC
The combination of lenvatinib and pembrolizumab outperformed sunitinib as first-line therapy for advanced clear-cell renal cell carcinoma (RCC) in the CLEAR trial.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - February 18, 2021 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

Rush Limbaugh Dies at 70 Following Lung Cancer Diagnosis Rush Limbaugh Dies at 70 Following Lung Cancer Diagnosis
Rush Limbaugh, for decades a popular, controversial, and influential talk radio host and conservative commentator, died Wednesday, according to a family statement.WebMD Health News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - February 18, 2021 Category: Cancer & Oncology Tags: Internal Medicine News Source Type: news

Adjuvant Nivolumab: A New Standard of Care in High-risk MIUC? Adjuvant Nivolumab: A New Standard of Care in High-risk MIUC?
Nivolumab is efficacious and well tolerated when used as adjuvant therapy in patients who have undergone radical surgery for high-risk, muscle-invasive urothelial carcinoma, new research suggests.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - February 15, 2021 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

PET Predicts Response to Endocrine Therapy in ER+ Breast Cancer PET Predicts Response to Endocrine Therapy in ER+ Breast Cancer
Only half the women with ER+ breast cancer who get endocrine therapy respond. Could functional tests and a PET scan identify those women?Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - February 15, 2021 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

First Drug That Protects Against Chemo-Induced Myelosuppression First Drug That Protects Against Chemo-Induced Myelosuppression
The FDA has approved trilaciclib (Cosela), a first-in-class drug given before chemotherapy to protect against chemo-induced bone marrow suppression.FDA Approvals (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - February 15, 2021 Category: Cancer & Oncology Tags: Hematology-Oncology News Alert Source Type: news

Androgen Annihilation Strategy Prolongs rPFS in mCRPC Androgen Annihilation Strategy Prolongs rPFS in mCRPC
Adding apalutamide to standard care significantly slows progression of chemotherapy-naive metastatic castration-resistant prostate cancer, according to the final results of a phase 3 trial.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - February 12, 2021 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

Drop in PSA Screening, Increase in Metastatic Prostate Cancers Drop in PSA Screening, Increase in Metastatic Prostate Cancers
The incidence of metastatic prostate cancers at diagnosis increased as prostate-specific antigen (PSA) screenings across U.S. states decreased, registry data show.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - February 12, 2021 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

Nearly 4 in 10 Cancer Deaths Attributable to Cigarette Smoking Nearly 4 in 10 Cancer Deaths Attributable to Cigarette Smoking
Rates vary around the US, but nearly 4 in 10 cancer deaths are attributable to cigarette smoking in parts of the South and Appalachia.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - February 12, 2021 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

Combo Disappoints in Metastatic Prostate Cancer Combo Disappoints in Metastatic Prostate Cancer
Combining the tyrosine kinase inhibitor saracatinib with docetaxel does not benefit patients with metastatic, castration-resistant prostate cancer, according to researchers.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - February 12, 2021 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

Cochrane Group Took 9 Months to Pull a Flawed Cancer Review Cochrane Group Took 9 Months to Pull a Flawed Cancer Review
In those 270 days, the paper, reporting findings that were literally directionally incorrect, was freely available for download for all those with access to the Cochrane Library.Retraction Watch (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - February 12, 2021 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

ASCO Endorses Guidelines on Radiation Therapy for SCLC ASCO Endorses Guidelines on Radiation Therapy for SCLC
The American Society of Clinical Oncology (ASCO) has endorsed guidelines on radiation therapy for patients with small cell lung cancer (SCLC).Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - February 12, 2021 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

Does Cancer Care Inspire Great Writing? Does Cancer Care Inspire Great Writing?
' When we wrestle with life and death on a daily basis, at some point, we need an outlet to share that struggle,'says one oncologist who also writes.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - February 12, 2021 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

Amivantamab Shows Promise in Challenging EGFR-Mutated NSCLC Amivantamab Shows Promise in Challenging EGFR-Mutated NSCLC
The novel drug appears to be effective for patients with EGFR-mutated NSCLC that has a hard-to-treat exon 20 insertion after disease progression with platinum-based chemotherapy.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - February 11, 2021 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

Neoadjuvant Atezolizumab Safe in Resectable Lung Cancer Neoadjuvant Atezolizumab Safe in Resectable Lung Cancer
In the LCMC3 study, patients received 1200 mg of neoadjuvant atezolizumab IV every 3 weeks for two cycles followed by resection between 30 and 50 days from the first cycle.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - February 11, 2021 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

Customized Chemotherapy Did Not Improve Survival in Early NSCLC Customized Chemotherapy Did Not Improve Survival in Early NSCLC
Tailoring adjuvant chemotherapy based on the expression of two molecular markers did not confer a survival advantage in patients with completely resected stage 2-3 NSCLC in a phase 3 trial.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - February 10, 2021 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

Combo Immunotherapy in NSCLC: Not These Two Drugs Combo Immunotherapy in NSCLC: Not These Two Drugs
Pembrolizumab monotherapy remains a standard of care, after trial results show that adding ipilimumab conveys no benefits but incurs greater toxicity.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - February 10, 2021 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

Biomarkers Predict Response to Checkpoint Inhibitors Biomarkers Predict Response to Checkpoint Inhibitors
Researchers have identified genetic and gene expression changes in tumors that may predict response to treatment with checkpoint inhibitors.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - February 10, 2021 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

' We Can Do Better': COVID-19 Vaccination in Cancer Patients'We Can Do Better': COVID-19 Vaccination in Cancer Patients
Patients with cancer should be prioritized for COVID vaccination, but only one third of state health departments have heeded the call. Mechanisms to find eligible patients, say advocates, are lacking.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - February 9, 2021 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

' Unprecedented' Long-term Survival After IO in Pretreated NSCLC'Unprecedented' Long-term Survival After IO in Pretreated NSCLC
For patients with non –small cell lung cancer (NSCLC) who experiecne disease progression with chemotherapy, immunotherapy (IO) offers an"unprecedented" chance of long-term survival, says an expert.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - February 9, 2021 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

USPSTF Plan for Revising Breast Screening Guidance Questioned USPSTF Plan for Revising Breast Screening Guidance Questioned
The USPSTF has begun the process of revising the 2016 guidelines for breast cancer screening, but an expert questions the draft research plan.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - February 9, 2021 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

Sotorasib in NSCLC:'Historic Milestone' Reached Sotorasib in NSCLC:'Historic Milestone' Reached
The KRAS inhibitor sotorasib provides durable clinical benefit in heavily pretreated patients with non –small cell lung cancer (NSCLC) harboring KRAS p.G12C mutations, results of a phase 2 trial suggest.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - February 9, 2021 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

Sifting Through the Wreckage of 2020: 5 Things Worth Salvaging Sifting Through the Wreckage of 2020: 5 Things Worth Salvaging
Treating cancer demands celebrating successes where you can find them. An oncologist looks back at a few of the beneficial adaptations that happened despite an otherwise abysmal year.Medscape Oncology (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - February 9, 2021 Category: Cancer & Oncology Tags: Hematology-Oncology Commentary Source Type: news

New Approach to Breast Screening Based on Breast Density at 40 New Approach to Breast Screening Based on Breast Density at 40
A proposed new approach to breast screening would use a baseline measure of breast density at age 40 to determine the frequency of future screenings.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - February 8, 2021 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

Legendary Oncologist Emil J. Freireich, MD, Dies at 93 Legendary Oncologist Emil J. Freireich, MD, Dies at 93
Recognized as the father of modern leukemia therapy and modern clinical cancer research, Emil Freireich, MD, was a faculty member of the MD Anderson Cancer Center for over 50 years.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - February 8, 2021 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

FDA Approves Umbralisib (Ukoniq) for Two Lymphomas FDA Approves Umbralisib (Ukoniq) for Two Lymphomas
The new drug has been granted an accelerated approval for use in patients with refractory or relapsed marginal zone lymphoma and follicular lymphoma.FDA Approvals (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - February 8, 2021 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

FDA OKs New CAR T- Cell Tx for Large B-cell Lymphomas FDA OKs New CAR T- Cell Tx for Large B-cell Lymphomas
Breyanzi is the first agent with an RMAT designation to be licensed by the FDA.FDA Approvals (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - February 6, 2021 Category: Cancer & Oncology Tags: Hematology-Oncology News Alert Source Type: news

Which Patients With Kidney Cancer Are Likely to Respond to ICI? Which Patients With Kidney Cancer Are Likely to Respond to ICI?
Several factors in patients with clear cell renal cell carcinoma are associated with a diminished response to immune checkpoint inhibition (ICI).Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - February 5, 2021 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

Fecal Transplant Overcomes Resistance to Immunotherapy Fecal Transplant Overcomes Resistance to Immunotherapy
Some patients with advanced melanoma who were unresponsive to pembrolizumab showed a response after receiving a fecal transplant.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - February 5, 2021 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

Oral Contraceptives Reduce Ovarian and Endometrial Cancer Risk Oral Contraceptives Reduce Ovarian and Endometrial Cancer Risk
Oral contraceptive use is associated with a decreased risk of ovarian and endometrial cancer 3 decades after discontinuation, according to an analysis of data from more than 250,000 women.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - February 5, 2021 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

FDA Grants MET Inhibitor Tepotinib Accelerated Approval for NSCLC FDA Grants MET Inhibitor Tepotinib Accelerated Approval for NSCLC
The US Food and Drug Administration has granted accelerated approval for tepotinib for the treatment of adults with metastatic non –small cell lung cancer harboring MET exon 14 skipping alterations.FDA Approvals (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - February 4, 2021 Category: Cancer & Oncology Tags: Hematology-Oncology News Alert Source Type: news

Does Surgery for Colorectal Liver Metastases Release Tumor Cells? Does Surgery for Colorectal Liver Metastases Release Tumor Cells?
Manipulation of the liver during surgery could release tumor cells into the bloodstream, but a comparison of two surgical techniques finds no difference in dissemination.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - February 4, 2021 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

Oncologists React to Ethical Controversies: Medscape Survey Oncologists React to Ethical Controversies: Medscape Survey
More than half of oncologists say that doctors should speak out when their needs aren't being met, and a growing number support physician-assisted dying.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - February 4, 2021 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

Increased Risk of Meningioma With Cyproterone Acetate Use Increased Risk of Meningioma With Cyproterone Acetate Use
A strong, dose-dependent association between use of cyproterone acetate and risk of meningioma requiring invasive treatment has been confirmed.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - February 4, 2021 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news