Does Obesity Reduce Drug Efficacy in Breast Cancer? Does Obesity Reduce Drug Efficacy in Breast Cancer?
Poor survival outcomes occurred among overweight patients treated with docetaxel-based adjuvant chemotherapy compared with peers given a non-taxane-based regimen.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - July 11, 2020 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

USPSTF: Earlier Lung Cancer Screening Can Double Eligibility USPSTF: Earlier Lung Cancer Screening Can Double Eligibility
New proposals to start screening at age 50 rather than 55, and after 20 rather than 30 pack-years of smoking, could benefit Black persons and women, say experts.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - July 9, 2020 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

FDA Approves Oral Therapy for Myelodysplastic Syndromes, CMML FDA Approves Oral Therapy for Myelodysplastic Syndromes, CMML
The Food and Drug Administration has approved Inqovi (decitabine and cedazuridine tablets, Astex Pharmaceuticals) to treat adults with myelodysplastic syndromes or chronic myelomonocytic leukemia (CMML).FDA Approvals (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - July 9, 2020 Category: Cancer & Oncology Tags: Hematology-Oncology News Alert Source Type: news

Drug-Drug Interactions to Avoid in Patients With GI Cancer Drug-Drug Interactions to Avoid in Patients With GI Cancer
Patients with gastrointestinal tumors can have potentially life-threatening complications from drug-drug interactions, including, for example, reactions between PPIs and cepacitabine.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - July 8, 2020 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

Study Supports Changing Classification of Renal Cell Carcinoma Study Supports Changing Classification of Renal Cell Carcinoma
The definition of stage 4 renal cell carcinoma should be expanded to include lymph node-positive stage 3 disease, according to a new study.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - July 7, 2020 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

Lifestyle Choices May Reduce Breast Cancer Risk Regardless of Genetics Lifestyle Choices May Reduce Breast Cancer Risk Regardless of Genetics
Women, regardless of genetic risk, may be able to reduce their risk of breast cancer through lifestyle changes, a large study of more than 90,000 women suggests.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - July 7, 2020 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

Radiomics Can Identify High-Risk Early Stage Lung Cancer Radiomics Can Identify High-Risk Early Stage Lung Cancer
Radiomics can improve lung cancer screening by identifying patients with early stage lung cancer at high risk for poorer outcomes who could benefit from aggressive therapy.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - July 7, 2020 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

Entrectinib Results Emphasize Need for NTRK Detection Entrectinib Results Emphasize Need for NTRK Detection
Although NTRK fusion genes are rare in gastrointestinal cancers, they should be looked for, inasmuch as responses to the TRK inhibitor entrectinib are robust and durable, say experts.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - July 7, 2020 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

CRC With Peritoneal Metastases: CRS-HIPEC Refinements CRC With Peritoneal Metastases: CRS-HIPEC Refinements
Refinements to the treatment pathway may improve overall survival in patients with colorectal cancer who have peritoneal metastases, suggest four new studies.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - July 7, 2020 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

Telephone Interventions Might Relieve Some Symptoms in Adults With Cancer Telephone Interventions Might Relieve Some Symptoms in Adults With Cancer
Telephone interventions offer some relief of depression and other symptoms in adults with cancer, but the certainty of evidence is generally low, according to a new Cochrane review.Reuters Health Information (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - July 3, 2020 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

Vitamin D Tied to Lower Risk for Immunotherapy-Induced Colitis Vitamin D Tied to Lower Risk for Immunotherapy-Induced Colitis
Preliminary results show for the first time that vitamin D intake may be tied to decreased risk for immunotherapy-induced colitis in patients with melanoma.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - July 2, 2020 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

New Study Supports Treating Cancer Now New Study Supports Treating Cancer Now
Dr David Kerr comments on a recent study that looked at one of the big unknowns when COVID-19 started: whether there is an increased risk for mortality for cancer patients undergoing chemotherapy.Medscape Oncology (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - July 2, 2020 Category: Cancer & Oncology Tags: Hematology-Oncology Commentary Source Type: news

Geographical Hot Spots for Early-Onset Colon Cancer Geographical Hot Spots for Early-Onset Colon Cancer
In more than 200 hot spots across the United States, there is a high prevalence of colorectal cancer in patients younger than 50, and for these patients, survival is significantly worse.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - July 1, 2020 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

Troublesome Weight Gain (and Loss) in a Prostate Cancer Cohort Troublesome Weight Gain (and Loss) in a Prostate Cancer Cohort
Prostate cancer survivors should maintain a healthy weight and avoid weight gain in order to improve mortality outcomes, concludes a large observational study. However, weight loss was not automatically advised.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - June 30, 2020 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

Pembro Approved for 1st-Line Use in MSI-H/dMMR Colorectal Cancer Pembro Approved for 1st-Line Use in MSI-H/dMMR Colorectal Cancer
The FDA gave a thumbs-up to pembrolizumab as first-line monotherapy for microsatellite instability-high or mismatch repair deficient colorectal cancer.FDA Approvals (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - June 30, 2020 Category: Cancer & Oncology Tags: Hematology-Oncology News Alert Source Type: news

FDA Approves In-home Breast Cancer Treatment FDA Approves In-home Breast Cancer Treatment
FDA Approvals (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - June 29, 2020 Category: Cancer & Oncology Tags: Hematology-Oncology News Alert Source Type: news

Tumor Markers'Valuable' for Relapse Detection in Rare CNS Tumors Tumor Markers'Valuable' for Relapse Detection in Rare CNS Tumors
The markers can be used to detect relapse with a high degree of sensitivity in patients with CNS nongerminomatous germ cell tumors, according to a pooled analysis of cooperative group trials.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - June 29, 2020 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

Venetoclax Plus LDAC Tops LDAC Alone in AML Venetoclax Plus LDAC Tops LDAC Alone in AML
Cytarabine plus venetoclax showed benefit in overall survival for treatment naive AML patients.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - June 29, 2020 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

ASCO 2020: GI Cancer Highlights From David Kerr ASCO 2020: GI Cancer Highlights From David Kerr
Dr David Kerr discusses recent data on colorectal cancer, presented at the virtual ASCO meeting.Medscape Oncology (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - June 27, 2020 Category: Cancer & Oncology Tags: Hematology-Oncology Commentary Source Type: news

Combo Carboplatin/Paclitaxel New Standard of Care for Anal Cancer Combo Carboplatin/Paclitaxel New Standard of Care for Anal Cancer
The combination of carboplatin plus paclitaxel was less toxic and trended toward better survival as compared with 5-fluorouracil and cisplatin.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - June 26, 2020 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

How One Center Continues Cancer Clinical Trials Despite COVID-19 How One Center Continues Cancer Clinical Trials Despite COVID-19
Whereas many cancer trials around the world have been suspended, the University of Iowa's Holden Comprehensive Cancer Center is still offering 95% of its program despite COVID-19.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - June 24, 2020 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

More Than 10,000 Excess Cancer Deaths due to COVID-19 Delays More Than 10,000 Excess Cancer Deaths due to COVID-19 Delays
The National Cancer Institute predicts that more than 10,000 excess cancer deaths will occur during next 10 years because of delays in diagnosis and treatment as a result of the COVID-19 pandemic.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - June 24, 2020 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

Ibrutinib-Venetoclax Produces High MRD-Negative Rates in CLL/SLL Ibrutinib-Venetoclax Produces High MRD-Negative Rates in CLL/SLL
A once-daily regimen of ibrutinib and venetoclax yielded molecular remissions in bone marrow and peripheral blood in a phase 2 trial.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - June 24, 2020 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

Sitting and Risk for Cancer Death; Moving Even a Little Helps Sitting and Risk for Cancer Death; Moving Even a Little Helps
Sitting for long periods was associated with an increased risk of dying from cancer, but moving just a little every day can help, say researchers reporting data from people wearing accelerometers.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - June 23, 2020 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

Novel Drug Imetelstat Shows Transfusion Independence in MDS Novel Drug Imetelstat Shows Transfusion Independence in MDS
The novel telomerase inhibitor allowed patients with lower-risk myelodyplastic syndrome (MDS) who were heavily dependent on transfusions to become transfusion independent for a median of 20 months.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - June 23, 2020 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

In Breast Cancer, Is Chemobrain Really'Endocrine Brain'? In Breast Cancer, Is Chemobrain Really'Endocrine Brain'?
Dr Kathy Miller explores how new data from the TAILORx trial change our understanding of a common but -- to date -- poorly defined side effect.Medscape Oncology (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - June 23, 2020 Category: Cancer & Oncology Tags: Hematology-Oncology Commentary Source Type: news

More ED Visits by Cancer Survivors With Financial Hardships More ED Visits by Cancer Survivors With Financial Hardships
Higher medical and nonmedical financial hardships are associated with more emergency department visits and also with lower use of some preventive services.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - June 22, 2020 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

' Unbelievably Exciting' Results in Rare Type of Breast Cancer'Unbelievably Exciting' Results in Rare Type of Breast Cancer
Three (of 17) women with advanced metaplastic breast cancer treated with a combination of immunotherapies showed dramatic and durable responses.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - June 20, 2020 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

FDA Gives Thumbs Up to Tazemetostat for Follicular Lymphoma FDA Gives Thumbs Up to Tazemetostat for Follicular Lymphoma
The FDA has granted accelerated approved of the EZH2 inhibitor tazemetostat (Tazverik) for the treatment of relapsed or refractory follicular lymphoma.FDA Approvals (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - June 19, 2020 Category: Cancer & Oncology Tags: Pharmacist News Alert Source Type: news

Metastatic Breast Cancer Symptom Management: 5 Things to Know Metastatic Breast Cancer Symptom Management: 5 Things to Know
By addressing MBC patients'perspectives on meaningful symptom improvement and priorities for symptom management, oncologists can ensure treatment is consistent with patient values and goals.Medscape Oncology (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - June 18, 2020 Category: Cancer & Oncology Tags: Hematology-Oncology Article Source Type: news

Three Practice-Informing Breast Cancer Trials From ASCO 2020 Three Practice-Informing Breast Cancer Trials From ASCO 2020
Dr Kathy Miller comments on three breast cancer trials presented at this year's virtual ASCO meeting and notes that even a negative trial can have a silver lining.Medscape Oncology (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - June 18, 2020 Category: Cancer & Oncology Tags: Hematology-Oncology Commentary Source Type: news

Cardiology Care Ups CV Monitoring, BP Control in Breast Cancer Cardiology Care Ups CV Monitoring, BP Control in Breast Cancer
A new study supports a broader role for cardiologists, beyond the current focus on cancer therapy-related cardiovascular complications.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - June 18, 2020 Category: Cancer & Oncology Tags: Cardiology News Source Type: news

Low-Dose CT Lung Cancer Screening Debated, Despite Evidence Low-Dose CT Lung Cancer Screening Debated, Despite Evidence
New findings from the NELSON study support the conclusion of the landmark NLST study -- that high-risk people should undergo screening for lung cancer -- but there are risks and uptake has been slow.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - June 18, 2020 Category: Cancer & Oncology Tags: Pulmonary Medicine News Source Type: news

New Option for AL Amyloidosis: Daratumumab Added to CyBorD New Option for AL Amyloidosis: Daratumumab Added to CyBorD
The addition of daratumumab to the standard CyBorD regimen produced'substantial'increases in hematologic response rates and delayed the time to organ failure.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - June 18, 2020 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

From a Tweet to the Lancet in 10 Weeks: COVID-Cancer Consortium From a Tweet to the Lancet in 10 Weeks: COVID-Cancer Consortium
The COVID-19 and Cancer Consortium started with a single tweet. Ten weeks later, it had recruited 317 collaborators and 110 global institutions, accrued data from 2300 patients, and had published in the Lancet.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - June 17, 2020 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

Cardioprotective Meds Underutilized in Patients With Cancer History Cardioprotective Meds Underutilized in Patients With Cancer History
Statin and antiplatelet use was especially suboptimal, despite patients having comparable CVD and risk factors to those without previous cancer.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - June 16, 2020 Category: Cancer & Oncology Tags: Cardiology News Source Type: news

Mid-Career Oncologist Cites Harassment, Leaves Top Center Mid-Career Oncologist Cites Harassment, Leaves Top Center
Pamela Kunz, an expert on neuroendocrine tumors, has left Stanford University after 19 years, citing"gender discrimination and harassment."Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - June 16, 2020 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

Lurbinectedin (Zepzelca) Approved for Metastatic SCLC Lurbinectedin (Zepzelca) Approved for Metastatic SCLC
The FDA has granted accelerated approval for use of this new drug in metastatic small cell lung cancer (SCLC) that has progressed after or during treatment with platinum-based chemotherapy.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - June 16, 2020 Category: Cancer & Oncology Tags: Hematology-Oncology News Alert Source Type: news

Trial Omitting Total Body Irradiation Before HSCT Stopped Early Trial Omitting Total Body Irradiation Before HSCT Stopped Early
A study to evaluate a chemo-conditioning only approach -- without total body irradiation -- before hematopoietic stem cell transplantation was stopped early as outcomes clearly favored irradiation.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - June 15, 2020 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

Safe to Skip Radiotherapy With Negative PET in Hodgkin Lymphoma Safe to Skip Radiotherapy With Negative PET in Hodgkin Lymphoma
Results from the international HD17 trial suggest that most patients with early stage infavorable Hodgkin lymphoma can be treated with chemotherapy alone.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - June 15, 2020 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

Eha 2020 eha 2020
Read clinically focused news coverage of key developments from EHA 2020Medscape Oncology (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - June 15, 2020 Category: Cancer & Oncology Tags: Conference Coverage Source Type: news

Pembro'New Treatment of Choice' for MSI-H/dMMR Metastatic CRC Pembro'New Treatment of Choice' for MSI-H/dMMR Metastatic CRC
David Kerr reports on the most important trial in colorectal cancer at ASCO 2020 from his kitchen, where he's'anchored'to his chair.Medscape Oncology (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - June 15, 2020 Category: Cancer & Oncology Tags: Hematology-Oncology Commentary Source Type: news

No OS Benefit With Gefitinib vs Chemo for EGFR + NSCLC No OS Benefit With Gefitinib vs Chemo for EGFR + NSCLC
Adjuvant gefitinib provides no overall survival benefit over standard chemotherapy for EGFR-mutant, resected, stage II-IIIA non – small cell lung cancer (NSCLC), according to results from the ADJUVANT trial.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - June 12, 2020 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

Clinical Pathways Slow Drug Spending in Community Oncology Clinical Pathways Slow Drug Spending in Community Oncology
High-value clinical pathways combined with regular, data-driven peer discussions about costs and outcomes slowed drug expenditures in a community practice.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - June 12, 2020 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

We Can't Afford to Be'Cost-Agnostic' With Our Cancer Patients We Can't Afford to Be'Cost-Agnostic' With Our Cancer Patients
Dr Jack West on how one oncologist's personal experience propelled her to make patients'financial hardships a viable treatment consideration.Medscape Oncology (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - June 11, 2020 Category: Cancer & Oncology Tags: Hematology-Oncology Article Source Type: news

Up-Front Stereotactic Radiosurgery an Option for SCLC Brain Mets Up-Front Stereotactic Radiosurgery an Option for SCLC Brain Mets
The trade-offs with first-line SRS without WBRT include a shorter time to new brain metastases without an apparent difference in overall survival, according to the FIRE-SCLC study.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - June 10, 2020 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

Weekly Cisplatin New Standard in Postop Head and Neck Cancer Weekly Cisplatin New Standard in Postop Head and Neck Cancer
In a randomized trial, weekly cisplatin plus radiotherapy has been shown to be not only less toxic than dosing once every three weeks but also achieves better outcomes.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - June 10, 2020 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

American Cancer Society Update:'It Is Best Not to Drink Alcohol'American Cancer Society Update:'It Is Best Not to Drink Alcohol '
Updated guidelines increase recommended levels of physical activity and increase the emphasis on reducing processed/red meat and processed foods, as well as eliminating alcohol.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - June 9, 2020 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

Thyroid Cancer Overdiagnosis Reaches Beyond Affluent Regions Thyroid Cancer Overdiagnosis Reaches Beyond Affluent Regions
Trends of over-screening seen in affluent economies appear to be spreading to middle-income countries as scanning becomes available.'In short, it is a global public health problem,'says author.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - June 9, 2020 Category: Cancer & Oncology Tags: Diabetes & Endocrinology News Source Type: news

' Disturbing Finding' on Black Patients With Cancer in Need of Opioids'Disturbing Finding' on Black Patients With Cancer in Need of Opioids
Black patients with cancer at end of life have less access to opioids and make more pain-related emergency department visits than whites, say researchers who found reductions in overall prescribing.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - June 8, 2020 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news