Biohaven's Verdiperstat, An Oral Myeloperoxidase Inhibitor, Selected For Platform Trial Collaboration At Massachusetts General Hospital's Healey and AMG Center For Amyotrophic Lateral Sclerosis (ALS)
NEW HAVEN, Conn., Sept. 18, 2019 -- (Healthcare Sales & Marketing Network) -- Biohaven Pharmaceutical Holding Company Ltd. (NYSE: BHVN) ("Biohaven" or the "Company"), a clinical stage biopharmaceutical company with a portfolio of late-... Biopharmaceuticals, Neurology Biohaven Pharmaceutical, verdiperstat, Amyotrophic Lateral Sclerosis (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - September 18, 2019 Category: Pharmaceuticals Source Type: news

Is This a Fasciculation?
Discussion Benign fasciculations are very common and occur in up to 70% of the general population. They occur at different points in people’s lives. They can be brought out by stress, poor sleep hygiene and caffeine. Caffeine has numerous uses especially for regulating sleep and attention. However too much can cause restlessness, jitteriness and sleep deprivation too. The recommended amount of caffeine for a teenager is < 2.5 mg/kg or 100-175 mg/day. A Red Bull® beverage has 80 mg of caffeine /12 ounces, while Mountain Dew® has 55 mg caffeine/12 ounces. A review of caffeine can be found here. Adolescents, if l...
Source: PediatricEducation.org - September 16, 2019 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

US WorldMeds lands new FDA approval
Louisville-based pharmaceutical company US WorldMeds LLC received Food and Drug Administration approval for a new use of its drug Myobloc. Myobloc can now be used to treat sialorrhea, commonly known as drooling. It's a common and unfortunate symptom that follows many neurological disorders such as Parkinson's Disease, amyotrophic lateral sclerosis (ALS), cerebral palsy and stroke to name a few. "We are committed to helping patients who struggle with confidence due to their sialorrhea," US WorldMeds… (Source: bizjournals.com Health Care:Pharmaceuticals headlines)
Source: bizjournals.com Health Care:Pharmaceuticals headlines - August 28, 2019 Category: Pharmaceuticals Authors: Chris Larson Source Type: news

US WorldMeds lands new FDA approval
Louisville-based pharmaceutical company US WorldMeds LLC received Food and Drug Administration approval for a new use of its drug Myobloc. Myobloc can now be used to treat sialorrhea, commonly known as drooling. It's a common and unfortunate symptom that follows many neurological disorders such as Parkinson's Disease, amyotrophic lateral sclerosis (ALS), cerebral palsy and stroke to name a few. "We are committed to helping patients who struggle with confidence due to their sialorrhea," US WorldMeds… (Source: bizjournals.com Health Care:Biotechnology headlines)
Source: bizjournals.com Health Care:Biotechnology headlines - August 28, 2019 Category: Biotechnology Authors: Chris Larson Source Type: news

Eye-controlled, power wheelchair performs well for ALS patients - Elliott MA, Malvar H, Maassel LL, Campbell J, Kulkarni H, Spiridonova I, Sophy N, Beavers J, Paradiso A, Needham C, Rifley J, Duffield M, Crawford J, Wood B, Cox EJ, Scanlan JM.
INTRODUCTION: Our pilot study tested the feasibility and performance of an eye-controlled power wheelchair for amyotrophic lateral sclerosis (ALS) patients. METHODS: In this prospective pilot study, participants drove the wheelchair three times aro... (Source: SafetyLit)
Source: SafetyLit - August 12, 2019 Category: International Medicine & Public Health Tags: Engineering, Physics, Structural Soundness and Failure Source Type: news

Motor neurone disease researchers find link to microbes in gut
Study could eventually lead to new treatments for neurodegenerative conditionScientists have found tantalising clues that the devastating condition motor neurone disease may be linked to changes in microbes that live in the gut.Studies in mice revealed that animals bred to develop amyotrophic lateral sclerosis (ALS), a form of the disease that affectedthe cosmologist Stephen Hawking, improved and lived longer when they were given an organism calledAkkermansia muciniphila.Continue reading... (Source: Guardian Unlimited Science)
Source: Guardian Unlimited Science - July 22, 2019 Category: Science Authors: Ian Sample Science editor Tags: Motor neurone disease Medical research Science Society Microbiology Source Type: news

Molecular 'clutch' puts infection-fighting cells into gear
(National Centre for Biological Sciences) An international team including University of Warwick scientists identifies proteins that drive activation of our immune response. Adaptor proteins act as a 'clutch' to move clusters of proteins within cellsCould open opportunities to design immune cells to combat specific problems. Protein condensates are involved; have been found to play roles in many biological processes and diseases, including Huntington's disease, amyotrophic lateral sclerosis, and types of cancer. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - July 22, 2019 Category: Biology Source Type: news

Biohaven's treatment for Lou Gehrig's disease fails to win FDA nod
Biohaven Pharmaceutical Holding Co Ltd said on Friday the U.S. health regulator failed to approve its treatment for amyotrophic lateral sclerosis, or Lou Gehrig's disease, sending its shares down nearly 6% in extended trading. (Source: Reuters: Health)
Source: Reuters: Health - July 19, 2019 Category: Consumer Health News Tags: healthNews Source Type: news

Taking out the protein garbage becomes more difficult as neurons age
(University of Pennsylvania School of Medicine) As cells age, their ability to shed harmful refuse declines. New research suggests that the deterioration of autophagy in aged neurons could be a risk factor for a suite of neurodegenerative diseases such as ALS (amyotrophic lateral sclerosis), Alzheimer's, and Parkinson's. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 19, 2019 Category: International Medicine & Public Health Source Type: news

Neuralstem Appoints Mary Ann Gray, Ph.D., to Board of Directors
GERMANTOWN, Md., July 18, 2019 -- (Healthcare Sales & Marketing Network) -- Neuralstem, Inc. (Nasdaq: CUR), a biopharmaceutical company focused on the development of nervous system therapies based on its neural stem cell and small molecule technologies, a... Biopharmaceuticals, Regenerative Medicine, Personnel Neuralstem, Amyotrophic Lateral Sclerosis, spinal cord injury, stem cell (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - July 18, 2019 Category: Pharmaceuticals Source Type: news

Higher BMI Linked to Lower ALS Risk Higher BMI Linked to Lower ALS Risk
The hypothesis that high body mass index guards against development of amyotrophic lateral sclerosis is reinforced by new research.Medscape Medical News (Source: Medscape Neurology and Neurosurgery Headlines)
Source: Medscape Neurology and Neurosurgery Headlines - July 3, 2019 Category: Neurology Tags: Neurology & Neurosurgery News Source Type: news

An efficient gait dynamics classification method for neurodegenerative diseases using brain signals - Mole SSS, Sujatha K.
Neurons of the human brain are primarily affected by the Huntington's disease (HD), Amyotrophic Lateral Sclerosis (ALS), Parkinson's disease and so on. Classification of these neurodegenerative diseases (NDD) is clinically important to analyze the destruct... (Source: SafetyLit)
Source: SafetyLit - June 30, 2019 Category: International Medicine & Public Health Tags: Ergonomics, Human Factors, Anthropometrics, Physiology Source Type: news

High BMI, Weight Gain Linked to Lasting Decrease in ALS Risk
THURSDAY, June 27, 2019 -- High body mass index (BMI) and weight gain are associated with a reduced long-term risk for amyotrophic lateral sclerosis (ALS), according to a study published online June 26 in Neurology. Ola Nakken, M.D., from the... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - June 27, 2019 Category: Pharmaceuticals Source Type: news

Protein offers protection against nerve degeneration in ALS model
(Boston University School of Medicine) Increasing the levels of the anti-aging protein hormone Klotho improves the neurological deficits and prolongs life span in an experimental model with Amyotrophic Lateral Sclerosis (ALS). In addition, brain immune cells called microglia play an important role in protecting the brain against inflammation and, likely, motor neuron loss in this model. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 27, 2019 Category: International Medicine & Public Health Source Type: news

Could Heavier Folks Be at Lower Risk for ALS?
WEDNESDAY, June 26, 2019 -- It ' s not often that anything good is associated with obesity. Yet heavy folks and those who bulk up as they age may have less risk for the deadly disease amyotrophic lateral sclerosis (ALS), a new study finds. The... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - June 26, 2019 Category: General Medicine Source Type: news