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Investigational Flu Drug a Near Match for Oseltamivir
(MedPage Today) -- Clinical outcomes'identical'but virology different (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - October 8, 2017 Category: Primary Care Source Type: news

Combination Antivirals Have Mixed Results in Treating Influenza (FREE)
By Kelly Young Edited by Susan Sadoughi, MD, and Andr é Sofair, MD, MPH A combination of amantadine, oseltamivir, and ribavirin is associated with reduced viral load in influenza but no clinical improvement over oseltamivir monotherapy, according to a phase … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - September 25, 2017 Category: Primary Care Source Type: news

Zydus' Nesher Pharma gets USFDA nod to market influenza drug
Zydus' Nesher Pharmaceuticals has received final approval from the USFDA to market Oseltamivir powder for oral suspension, 6 mg/ml, said the company. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - September 16, 2017 Category: Pharmaceuticals Source Type: news

Generic for Liquid Tamiflu Approved
(MedPage Today) -- First oseltamivir generic to win OK (Source: MedPage Today Public Health)
Source: MedPage Today Public Health - September 15, 2017 Category: American Health Source Type: news

FDA Clears First Generic Tamiflu for Oral Suspension FDA Clears First Generic Tamiflu for Oral Suspension
Oseltamivir phosphate (Tamiflu) for oral suspension 6 mg(base)/mL, made by Nesher Pharmaceuticals LLC, is particularly important for patients who can't swallow pills, the FDA notes.FDA Approvals (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - September 15, 2017 Category: Consumer Health News Tags: Family Medicine/Primary Care News Alert Source Type: news

Expert panel reviews neuraminidase inhibitors for the prevention and treatment of influenza
(European Centre for Disease Prevention and Control (ECDC)) An ECDC expert opinion concludes that there is clear evidence supporting the use of neuraminidase inhibitors in the treatment and prevention of influenza. Moreover, the current recommendations in European countries on the use of the neuraminidase inhibitors oseltamivir and zanamivir are appropriate and should be applied by prescribing physicians. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 16, 2017 Category: International Medicine & Public Health Source Type: news

Letter to the Editor: Tamiflu Works Well, Unlike Other Antibiotics
No abstract available (Source: Emergency Medicine News)
Source: Emergency Medicine News - July 1, 2017 Category: Emergency Medicine Tags: Letter to the Editor Source Type: news

Efficacy of Clarithromycin-Naproxen-Oseltamivir Combination in the Treatment of Patients Hospitalized for Influenza A(H3N2) Infection: An Open-label Randomized, Controlled, Phase IIb/III Trial
This study has led to a Practice Changing Update on DynaMed Plus. It found that clarithromycin plus naproxen plus oseltamivir for 2 days followed by oseltamivir for 3 days may reduce mortality compared to oseltamivir alone for 5 days in hospitalized older adults with influenza A (H3N2) and pneumonia (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - June 29, 2017 Category: Consumer Health News Source Type: news

Pimodivir Alone or in Combination with Oseltamivir Demonstrated a Significant Reduction in Viral Load in Adults with Influenza A
- Phase 2b results presented at the 5th International Society for Influenza and Respiratory Diseases Antiviral Group (ISIRV-AVG) Conference - (Source: Johnson and Johnson)
Source: Johnson and Johnson - June 14, 2017 Category: Pharmaceuticals Source Type: news

Letter to the Editor: Flu Shot's Abysmal Track Record Akin to Tamiflu's
No abstract available (Source: Emergency Medicine News)
Source: Emergency Medicine News - June 1, 2017 Category: Emergency Medicine Tags: Letter to the Editor Source Type: news

Frog slime could protect us against future flu epidemic
Conclusion This study has identified a substance in the mucus secreted by a south Indian frog which can kill certain types of flu virus. Researchers often turn to natural substances with known health-giving properties to find potential new drugs for humans. For example, aspirin was developed based on a compound found in willow bark – which had been used in traditional medicine for hundreds of years. Some other drugs – such as some chemotherapy and anticlotting drugs – have also been developed from chemicals found in plants. By isolating the substances that have an effect the researchers can make sure...
Source: NHS News Feed - April 19, 2017 Category: Consumer Health News Tags: Heart/lungs Medication Medical practice Source Type: news

Myths in Emergency Medicine: Still Prescribing Oseltamivir?
No abstract available (Source: Emergency Medicine News)
Source: Emergency Medicine News - April 1, 2017 Category: Emergency Medicine Tags: Myths in Emergency Medicine Source Type: news

Vaccines do work for pandemic flu
Vaccine against swine flu in 2009 prevented infections and hospitalisations Related items fromOnMedica Tamiflu reduced risk of death in H1N1 influenza pandemic Nasal spray flu vaccine for children proving effective Antenatal flu drugs not linked to newborn risks Flu jab linked to fewer hospitalisations World ‘not prepared’ for Zika and Ebola (Source: OnMedica Latest News)
Source: OnMedica Latest News - March 13, 2017 Category: UK Health Source Type: news

Vouching for the Fetal Safety of Neuraminidase Inhibitors During Pregnancy (FREE)
By Anna Wald, MD, MPH Dr. Wald is an associate editor with NEJM Journal Watch Women's Health, from which this story was adapted. Full coverage is available at the link below.Treating pregnant women with oseltamivir … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - February 28, 2017 Category: Primary Care Source Type: news

Zydus subsidiary receives USFDA nod to market Tamiflu drug
The group now has more than 110 approvals and has so far filed over 300 ANDAs since the commencement of the filing process in 2003-04 fiscal (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - February 27, 2017 Category: Pharmaceuticals Source Type: news

Windtree touts preclinical data from influenza study for aerosolized surfactant
Windtree Therapeutics (NSDQ:WINT) said today that a preclinical influenza study demonstrated that its aerosolized KL4 surfactant reduced lung inflammation and improved overall survival in ferrets. In the preclinical study, researchers compared Windtree’s aerosolized KL4 surfactant with a daily oral dose of oseltamivir, an antiviral, and placebo controls. Following exposure to the influenza virus, investigators evaluated the ferrets for clinical signs of infection and lung histopathology changes. Get the full story at our sister site, Drug Delivery Business News. The post Windtree touts preclinical data from infl...
Source: Mass Device - February 16, 2017 Category: Medical Equipment Authors: Sarah Faulkner Tags: Drug-Device Combinations Pharmaceuticals Wall Street Beat Windtree Therapeutics Source Type: news

Are antivirals a cost-effective therapy during severe flu seasons?
(Wiley) A new study indicates that the antiviral drug oseltamivir can reduce influenza infections and prevent deaths in a cost-saving manner under most pandemic scenarios. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 8, 2017 Category: Global & Universal Source Type: news

CO2, the philosopher's stone to obtain valuable pharmaceuticals
(Institute of Chemical Research of Catalonia (ICIQ)) Starting from readily available materials and CO2, ICIQ researchers prepare useful building blocks named 'cyclic carbonates' that can be converted into valuable pharmaceuticals like Tamiflu ® . (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - January 13, 2017 Category: Biology Source Type: news

Morning Break:'Poorly Trained Surgeon'; Generic Tamiflu; Tiny Reindeer
(MedPage Today) -- Health news and commentary from around the Web, gathered by the MedPage Today staff (Source: MedPage Today Psychiatry)
Source: MedPage Today Psychiatry - December 12, 2016 Category: Psychiatry Source Type: news

Generic copy of Roche flu pill Tamiflu hits U.S. market
(Reuters) - The first generic copy of Roche's top-selling flu pill Tamiflu hit the U.S. market on Monday, marking a further  step in the Swiss drugmaker's enforced evolution to reliance on a new wave of blockbuster medicines. (Source: Reuters: Health)
Source: Reuters: Health - December 12, 2016 Category: Consumer Health News Tags: healthNews Source Type: news

Natco Pharma launches Tamiflu generic capsules in US
The company's capsules are generic versions of Roche's Tamiflu drug (Source: The Economic Times)
Source: The Economic Times - December 12, 2016 Category: Consumer Health News Source Type: news

Assessing Fever in Returning Travelers: Part II
  Zika continues to be the virus of the day for returning travelers, but there are several other diseases that we need to consider in these patients when they present to us in the emergency department. Chikungunya is epidemic in many of the same countries as Zika and can be even more devastating. And Avian and MERS-CoV is still present in many countries. Unlike patients infected with Zika virus, these patients do require isolation to protect our health care staff from infection. Chikungunya Chikungunya, which means “to walk bent over,” was likely endemic but unrecognized in the United States before the mos...
Source: EPMonthly.com - November 25, 2016 Category: Emergency Medicine Authors: Matt McGahen Tags: Uncategorized Source Type: news

How Effective is Oseltamivir?
Discussion Oseltamivir (Tamiflu®) is an oral neuraminidase inhibitor of influenza viruses types A and B. It first came on the market in Switzerland in 1999 and currently is used around the world along with other neuraminidase inhibitors to treat seasonal and pandemic influenza. Oseltamivir is easily absorbed from the gastrointestinal tract, and circulates to the liver where it is converted to its active metabolite oseltamivir carboxylate (OC). In adults approximately 75% of the oral medication is converted and it then travels to the upper and lower respiratory tracts. Unchanged oseltamivir is eliminated in the urine. ...
Source: PediatricEducation.org - September 5, 2016 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

FDA approves generic version of Tamiflu
The Food and Drug Administration has approved the first generic version of Tamiflu (oseltamivir phosphate), a medication for the treatment of influenza A and B. The announcement was made Aug. 3,... (Source: Family Practice News)
Source: Family Practice News - August 12, 2016 Category: Primary Care Source Type: news

First Generic Version of Tamiflu Approved by FDA
(Source: WebMD Health)
Source: WebMD Health - August 5, 2016 Category: Consumer Health News Source Type: news

FDA Approves First Generic Version of Widely Used Influenza Drug Tamiflu
On August 3, 2016, the U.S. Food and Drug Administration approved the first generic version of Tamiflu (oseltamivir phosphate), a widely used medication for the treatment of the flu (influenza A and B) in patients two weeks of age and older who have... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - August 4, 2016 Category: Pharmaceuticals Source Type: news

FDA Approves First Generic Tamiflu FDA Approves First Generic Tamiflu
The agency cautioned that it doesn't know if oseltamivir works in people who start taking it 2 days after the start of symptoms, or who have weak immune systems.FDA Approvals (Source: Medscape Allergy Headlines)
Source: Medscape Allergy Headlines - August 4, 2016 Category: Allergy & Immunology Tags: Infectious Diseases News Alert Source Type: news

First Generic Tamiflu Approved (FREE)
By the Editors The FDA has approved the first generic oseltamivir (trade name, Tamiflu) to treat … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - August 4, 2016 Category: Primary Care Source Type: news

Natco Pharma gets ANDA nod for Tamiflu's generic version
Tamiflu is used to treat the flu (influenza) in people 2 weeks of age and older who have had flu symptoms for no more than 2 days. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - August 4, 2016 Category: Pharmaceuticals Source Type: news

Debate Regarding Oseltamivir Use for Influenza Debate Regarding Oseltamivir Use for Influenza
How effective is oseltamivir against seasonal and pandemic influenza? The debate over the appropriate use of the antiviral drug continues.Emerging Infectious Diseases (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - August 3, 2016 Category: Consumer Health News Tags: Infectious Diseases Journal Article Source Type: news

Tamiflu (Oseltamivir Phosphate) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - June 30, 2016 Category: Drugs & Pharmacology Source Type: news

Pregnant Women Benefit From Tamiflu at First Sign of Flu: Study
During pregnancy, risk of serious complications and death from the illness intensifies (Source: Pulmonary Medicine News - Doctors Lounge)
Source: Pulmonary Medicine News - Doctors Lounge - February 9, 2016 Category: Respiratory Medicine Authors: webmaster at doctorslounge.com Tags: Gynecology, Obstetrics, Infections, Pulmonology, News, Source Type: news

Pregnant Women Benefit From Tamiflu at First Sign of Flu: Study
TUESDAY, Feb. 9, 2016 -- Early treatment with the antiviral drug Tamiflu (oseltamivir) may shorten hospital stays for pregnant women with the flu, especially those who are severely ill, new research suggests. Pregnant women are at increased risk... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - February 9, 2016 Category: Journals (General) Source Type: news

Early Tamiflu Helps Pregnant Women With Flu (CME/CE)
(MedPage Today) -- Drug given within 2 days of illness onset shortens hospital stay (Source: MedPage Today Pulmonary)
Source: MedPage Today Pulmonary - February 5, 2016 Category: Respiratory Medicine Source Type: news

Fighting flu with designer drugs: A new compound fends off different influenza strains
A study published on February 4th in PLOS Pathogens reports that a new antiviral drug protects mice against a range of influenza virus strains. The compound seems to act superior to Oseltamivir (Tamiflu) and independent of the host immune response. (Source: World Pharma News)
Source: World Pharma News - February 5, 2016 Category: Pharmaceuticals Tags: Featured Research Research and Development Source Type: news

Drug which both prevents and treats flu is 'more effective than Tamiflu'
Scientists at the University of Washington, Seattle, developed a drug which works by binding to influenza proteins known as hemagglutinin (HA) and neuraminidase (NA), pictured. (Source: the Mail online | Health)
Source: the Mail online | Health - February 4, 2016 Category: Consumer Health News Source Type: news

For pregnant women with flu, the earlier the better for antiviral treatment
(Infectious Diseases Society of America) Pregnant women are at higher risk for serious illness and complications, including death, from influenza. For expectant mothers hospitalized with flu, early treatment with the influenza antiviral drug oseltamivir may shorten their time in the hospital, especially in severe cases, suggests a new study published in The Journal of Infectious Diseases and available online. The findings also underscore the importance of flu vaccination for this risk group. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 4, 2016 Category: Global & Universal Source Type: news

Fighting flu with designer drugs: A new compound fends off different influenza strains
(PLOS) A study published on Feb. 4 in PLOS Pathogens reports that a new antiviral drug protects mice against a range of influenza virus strains. The compound seems to act superior to oseltamivir (Tamiflu) and independent of the host immune response. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - February 4, 2016 Category: Infectious Diseases Source Type: news

Under the weather? A blood test can tell if antibiotics are needed
Dr. Ephraim Tsalik assesses Charles Watts for a respiratoryinfection in the ER at the Durham VA Medical Center. DURHAM, N.C. -- Researchers at Duke Health are fine-tuning a test that can determine whether a respiratory illness is caused by infection from a virus or bacteria so that antibiotics can be more precisely prescribed. The team of infectious disease and genomics experts at Duke has developed what they call gene signatures, patterns that reflect which of a patient’s genes are turned on or off, to indicate whether someone is fighting infection from a virus or bacteria. Results can be derived from a small sample...
Source: DukeHealth.org: Duke Health Features - January 20, 2016 Category: Pediatrics Tags: Duke Medicine Source Type: news

Researchers identify previously unknown mystery virus that killed Kansas man in 2014
(NaturalNews) Have you ever heard of wild-type viruses? When the mainstream medical system tries to eradicate a virus from the population using singular-mode antiviral drugs and vaccines, they are only increasing a virus's mutating ability. For example, the antiviral drug Tamiflu... (Source: NaturalNews.com)
Source: NaturalNews.com - January 14, 2016 Category: Consumer Health News Source Type: news

Is paracetamol any good for treating flu?
ConclusionThis double-blind, randomised controlled trial aimed to assess the effect of paracetamol on reducing viral load and clinical symptoms of flu. The researchers found paracetamol had no effect on any outcome in people with flu – on viral load, temperature or clinical symptoms – and feel there is not enough evidence to provide the drug as a treatment. However, there are a few points to bear in mind. The randomised design and double-blind nature of the trial are strengths, as these should reduce the risk of bias in how patients were allocated to groups, as well as the risk of bias in outcome reporting...
Source: NHS News Feed - December 14, 2015 Category: Consumer Health News Tags: Heart/lungs Medication Source Type: news

Natco settles patent suit with Gilead, others over Tamiflu
Natco Pharma and its partner Alvogen today said they have settled patent infringement suit with Gilead Sciences Inc and others over Tamiflu. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - December 14, 2015 Category: Pharmaceuticals Source Type: news

Scientists Hope Tracking Winter Flu Will Help Close Pandemic Knowledge Gap
ImageContent(562e45c2e4b0aac0b8fd7c69,562e42a91900002e00b94dab,Image,HectorAssetUrl(562e42a91900002e00b94dab,Some(),Some(jpeg)),ViktorCap via Getty Images,) Anyone who goes down with flu in Europe this winter could be asked to enroll in a randomized clinical trial in which they will either be given a drug, which may or may not work, or standard advice to take bed rest and paracetamol. Those who agree could be helping the world prepare for the next potentially deadly disease pandemic as well as helping scientists who are now desperate to plug gaps in knowledge left by previous missed opportunities. Scientists are largely in...
Source: Science - The Huffington Post - October 26, 2015 Category: Science Source Type: news

Lack of trial data may lead to wrong clinical choices
Data access should be mandatory, argue authorsRelated items from OnMedicaDoctors’ leaders consult on ethical use of dataDrug giant agrees to release all Tamiflu trial dataNICE rejects arguments against wider statin useUS doctor says FDA should have withdrawn rosuvastatinTime to rethink 4.5h window for alteplase after stroke (Source: OnMedica Latest News)
Source: OnMedica Latest News - October 23, 2015 Category: UK Health Source Type: news

Flu drug given out "indiscriminately"
The antiviral drug Tamiflu was handed out "indiscriminately" during the last swine flu outbreak, a leading panel of UK scientists warns. (Source: BBC News | Health | UK Edition)
Source: BBC News | Health | UK Edition - October 8, 2015 Category: Consumer Health News Source Type: news

Experts call for tests on use of flu drugs in pandemic
Report says there is a lack of good data on how well Tamiflu works in the community, after missed opportunity during swine flu outbreakNew trials are urgently needed to establish whether the anti-flu drug Tamiflu would help save lives in a pandemic, experts have said.Flu pandemics are highly dangerous, with the potential to kill millions around the world. Each winter in the UK, hundreds die of flu. Yet the drugs available to treat people, of which the best known and most widely used is Tamiflu, appear to have only a modest effect and have only been tested on seasonal flu, according to a report by the Academy of Medical Sci...
Source: Guardian Unlimited Science - October 7, 2015 Category: Science Authors: Sarah Boseley Health editor Tags: Flu Health Pharmaceuticals industry Medical research Society Science UK news Source Type: news

Trial results expose Tamiflu's limitations in preventing pandemics
Independent researchers studying findings say drug carries side-effects and fails to reduce need for hospital treatmentResponding to the avian flu pandemic in 2006, the UK government went on to spend £424m on stockpiling Tamiflu over six years, believing it to be money well spent. Since then, however, full information from trials of the drug has been released to independent researchers at the Cochrane Collaboration, a global not-for-profit organisation. They concluded that while Tamiflu did reduce the length of time that symptoms were suffered, the drug came with side-effects and did not reduce the number of people t...
Source: Guardian Unlimited Science - August 31, 2015 Category: Science Authors: Simon Bowers Tags: Drugs Epidemics World news Pharmaceuticals industry Politics UK news Science Flu pandemic Health Society Source Type: news

GPs will have to declare gifts and hospitality
‘Sunshine rule’ from next year makes declarations compulsory Related items from OnMedicaPharma plans to boost transparency of its financial links to healthcare sectorCall for GMC to register doctors’ competing interestsGMC’s commitment to regulate doctors’ financial and commercial interests questionedAre industry ‘supertrialists’ imbalancing diabetes research?Experts question industry-funded study showing benefits of Tamiflu (Source: OnMedica Latest News)
Source: OnMedica Latest News - August 25, 2015 Category: UK Health Source Type: news

Echinacea preparation as effective as Tamiflu in early flu cases in large clinical trial
(NaturalNews) An Echinacea extract is just as effective as the antiviral drug Tamiflu at speeding recovery from flu infection, according to a study published in the journal Current Therapeutic Research.The new findings build on prior research which showed that Echinacea acts as... (Source: NaturalNews.com)
Source: NaturalNews.com - July 8, 2015 Category: Consumer Health News Source Type: news

Chief medical officer calls for review after statins and Tamiflu storm
Sally Davies writes to Royal Academy of Science in wake of negative press and public concern regarding the drugsThe chief medical officer, Sally Davies, has requested an expert review to shore up public confidence about the safety and effectiveness of medicines, in the wake of controversy around statins and Tamiflu.Davies wrote to ask the Royal Academy of Science if it would undertake the work. “I am very concerned about the lack of resolution of the statins and side-effects issues in both the medical and general press,” she said. Continue reading... (Source: Guardian Unlimited Science)
Source: Guardian Unlimited Science - June 16, 2015 Category: Science Authors: Sarah Boseley Health editor Tags: Health Society The National Institute for Health and Care Excellence (Nice) Medical research Statins NHS UK news Source Type: news