‘It wouldn’t exist’: Viagra inventor tells how Welsh miners began its rise
Dr David Brown says erectile dysfunction drug, subject of a BBC drama, could have been scrapped if a miner hadn ’t spoken outIt was the ultimate serendipitous discovery: a failed heart medication that became a multibillion-dollar erectile dysfunction drug. But the blockbuster story ofViagra could have ended differently were it not for the frankness of the Welsh miners who took part in a clinical trial just before the drug was due to be scrapped, according to Viagra ’s co-inventor.Speaking before the screening ofMen Up, a new BBC drama, executive produced by Russell T Davies, about the ordinary middle-aged Welsh men who...
Source: Guardian Unlimited Science - December 2, 2023 Category: Science Authors: Hannah Devlin Science correspondent Tags: Viagra Medical research Men's health Sex Pfizer Wales BBC Russell T Davies Pharmaceuticals industry Society UK news Source Type: news
Scientists in Discredited Alcohol Study Will Not Advise U.S. on Drinking Guidelines
Two researchers with ties to beer and liquor companies had been named to a panel that will review the health evidence on alcohol consumption. But after a New York Times story was published, the panel ’s organizers decided to drop them. (Source: NYT Health)
Source: NYT Health - December 2, 2023 Category: Consumer Health News Authors: Roni Caryn Rabin Tags: your-feed-science Conflicts of Interest Alcoholic Beverages Diet and Nutrition Research Medicine and Health Liquor Clinical Trials National Academies of Sciences, Engineering and Medicine Health and Human Services Department National I Source Type: news
'Alexa, Titrate My Insulin': AI App Boosts Glycemic Control in Randomized Trial
(MedPage Today) -- A custom artificial intelligence (AI) app for insulin management advice helped patients with type 2 diabetes gain rapid glycemic control, a small randomized clinical trial found.
In titrating basal insulin, those who used a... (Source: MedPage Today Nephrology)
Source: MedPage Today Nephrology - December 1, 2023 Category: Urology & Nephrology Source Type: news
Pfizer nixes more study of twice-daily obesity pill treatment that made many patients nauseous
FILE - The Pfizer logo is displayed at the company's headquarters, Friday, Feb. 5, 2021, in New York. Pfizer shares sank Friday, Dec. 1, 2023, when the drugmaker announced that it was abandoning a twice-daily obesity treatment after more than half the patients in a clinical trial stopped taking…#pfizer #apphoto #marklennihan #novonordisk #elililly #novo #obese #elilillys #mikaeldolsten #danuglipron (Source: Reuters: Health)
Source: Reuters: Health - December 1, 2023 Category: Consumer Health News Source Type: news
Local medical business owner gets nearly 6 years in prison for clinical trial fraud scheme
Another worker involved was given a lesser sentence of just under four years. (Source: bizjournals.com Health Care:Pharmaceuticals headlines)
Source: bizjournals.com Health Care:Pharmaceuticals headlines - December 1, 2023 Category: Pharmaceuticals Authors: Eman Elshahawy Source Type: news
Cochrane Mexico's'citizen scientist' event contributes to global research efforts
Cochrane Crowd is a global community of volunteers who are helping to classify the research needed to support informed decision-making about health care.Cochrane Mexico recently hosted its third screening challenge that helped introduce students to randomized control trials and evidence assessment. This event not only fostered the value of evidence synthesis among students but also made a significant contribution to ongoing global research efforts. The job of the Cochrane Crowd community is to review descriptions of research studies to identify and classify randomized controlled trials (RCTs), a type of study that is co...
Source: Cochrane News and Events - December 1, 2023 Category: Information Technology Authors: Muriah Umoquit Source Type: news
Pfizer nixes more study of twice-daily obesity pill treatment that made many patients nauseous
Pfizer shares sank Friday when the drugmaker announced that it was abandoning a twice-daily obesity treatment after more than half the patients in a clinical trial stopped taking it (Source: ABC News: Health)
Source: ABC News: Health - December 1, 2023 Category: Consumer Health News Tags: Health Source Type: news
CAD/CAM-based 3D-printed and PVS indirect bonding jig system accuracy: a systematic review, meta-analysis, and comparative analysis of hard and soft CAD/CAM transfer trays
Conclusions and implications:
CAD/CAM transfer trays provide high bracket positioning accuracy,
with soft transfer trays offering greater precision than rigid ones.
Future randomized prospective trials are required to enhance the
strength of the available evidence. (Source: Dental Technology Blog)
Source: Dental Technology Blog - December 1, 2023 Category: Dentistry Source Type: news
Medical device giant Johnson & Johnson swallows small North Bay company
The deal for the four-year-old Santa Rosa company, which will start enrolling a pivotal clinical trial early next year, includes milestone payments. (Source: bizjournals.com Health Care:Pharmaceuticals headlines)
Source: bizjournals.com Health Care:Pharmaceuticals headlines - November 30, 2023 Category: Pharmaceuticals Authors: Ron Leuty Source Type: news
Upstate embarks on traumatic brain injury clinical trial
Trial will investigate efficacy of two types of treatment strategies. (Source: SUNY Upstate Medical)
Source: SUNY Upstate Medical - November 30, 2023 Category: Universities & Medical Training Tags: News Source Type: news
10 Things You Didn't Know About Decentralized Clinical Trials, Upcoming Webinar Hosted by Xtalks
In this free webinar, gain insights into operationalizing a virtual site for a direct-to-patient clinical trial. The featured speakers will share insights on how to handle oversight and manage adverse events (AE) with a virtual site, how to handle recruitment with a decentralized clinical... (Source: PRWeb: Medical Pharmaceuticals)
Source: PRWeb: Medical Pharmaceuticals - November 30, 2023 Category: Pharmaceuticals Tags: TDS Source Type: news
Stock Down 63% Today?
BioVie (NASDAQ:BIVI) stock is falling on Wednesday after the company released data from a Phase 3 clinical trial of its Alzheimer’s Disease treatment candidate NE3107. Unfortunately for investors in BIVI stock, that study failed to meet its primary endpoint of statistical significance. The company…#biovie #ne3107 #cuongdo #unitysoftware #ussteel #latestussteel #williamwhite (Source: Reuters: Health)
Source: Reuters: Health - November 29, 2023 Category: Consumer Health News Source Type: news
The rise and rise...and rise of Viagra: How the 'little blue pill' was discovered by accident after Welsh miners took part in trials for new angina drug with unexpected results - before it ended up in millions of bedrooms across the world
The drug, which was synthesised at Pfizer 's lab in Sandwich, Kent, was put through a series of clinical trials, but the results were disappointing. (Source: the Mail online | Health)
Source: the Mail online | Health - November 29, 2023 Category: Consumer Health News Source Type: news
The Evolutionary Origins of Psychedelics
Humans rely on a bevy of strange natural chemicals to liven up our food and drink, to endure pain, and to change our perspective. We use caffeine from coffee, tea, and yerba mate to stimulate our bodies and minds, capsaicin from red pepper flakes or isothiocyanates in horseradish or wasabi to enliven our food with spice, and codeine or morphine to endure the pain of injuries and surgeries.
Lately, though, some have also turned to psychedelics like psilocybin to change their perspectives. In fact, researchers are beginning to test if they could serve as new treatments for mental health disorders.
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Source: TIME: Health - November 29, 2023 Category: Consumer Health News Authors: Noah Whiteman Tags: Uncategorized freelance Source Type: news
Bayer reports results of phase II gadoquatrane clinical trial at RSNA
Bayer presented positive results of its phase II clinical trial of macrocyclic gadolinium-based compound gadoquatraine in a scientific session at RSNA 2023 held on November 26.
The results showed that gadoquatrane, with a dose of 0.4 mmol gd/kg body weight, has a similar efficacy to 0.1 mmol Gd/kg bw of gadobutrol for MRI imaging.
The purpose of the phase II study was to establish a dose of gadoquatraine with similar procedures of the central nervous system (CNS) in patients with known or highly suspected CNS lesions.
The positive news of this phase of the drug’s clinical development program, dubbed QUANTI, has launch...
Source: AuntMinnie.com Headlines - November 28, 2023 Category: Radiology Authors: AuntMinnie.com staff writers Tags: Industry News Nuclear Radiology RSNA 2023 Source Type: news
