Bharat Biotech begins clinical trials of TB vaccine on adults in India
Bharat Biotech International Ltd has initiated clinical trials for the Tuberculosis vaccine Mtbvac on adults in India. Developed by the Spanish biopharmaceutical company Biofabri, Mtbvac is the first TB vaccine derived from a human source. The vaccine aims to be more effective and longer-lasting than the current BCG vaccine for newborns and to prevent TB in adults and adolescents, for whom there is currently no effective vaccine. The trials are a significant step, especially in a country like India where 28% of the world's TB cases occur. (Source: The Economic Times)
Source: The Economic Times - March 24, 2024 Category: Consumer Health News Source Type: news
Alzheimer ’s ‘breakthrough’ stalls: why a much-hyped drug is facing approval delays
The benefits of drugs such as donanemab, aducanumab and lecanemab are proving harder to quantify than potential harms, experts sayIt was heralded in news articles as a “breakthrough”, a “turning point” and a “gamechanger” for Alzheimer’s disease. Some experts went so far as to call the drug, donanemab, the “beginning of the end” for the debilitating condition.Pharmaceutical company Eli Lillyin May 2023 released data from a clinical trial they said showed donanemab slowed cognitive and functional decline in people with early symptomatic Alzheimer ’s disease by 35% over 18 months.Continue reading... (Sour...
Source: Guardian Unlimited Science - March 23, 2024 Category: Science Authors: Melissa Davey Medical editor Tags: Dementia Alzheimer's Health Medical research Australia news Source Type: news
Moleculin Reports Full Year 2023 Financial Results
– Year marked by growing body of positive Annamycin efficacy and safety clinical data expected to support advancement into a pivotal study for AML – Company to host conference call and webcast Monday, March 25th at 8:30 AM ET – Company to issue separate clinical trial update press release... (Source: PRWeb: Medical Pharmaceuticals)
Source: PRWeb: Medical Pharmaceuticals - March 22, 2024 Category: Pharmaceuticals Tags: ERN Source Type: news
EU Backs First Oral Monotherapy for Adults With PNH EU Backs First Oral Monotherapy for Adults With PNH
The European Medicines Agency has recommended Fabhalta for treating paroxysmal nocturnal hemoglobinuria after reviewing clinical trial results.Medscape Medical News (Source: Medscape Pharmacist Headlines)
Source: Medscape Pharmacist Headlines - March 22, 2024 Category: Drugs & Pharmacology Tags: Hematology-Oncology Source Type: news
Drug Could Extend Survival for Uterine Cancer Patients
FRIDAY, March 22, 2024 -- An already approved cancer drug could be an effective treatment for women with advanced, recurring uterine cancer, a new clinical trial shows.Rucaparib, which belongs to a class of drugs called PARP inhibitors, extended... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - March 22, 2024 Category: General Medicine Source Type: news
Rucaparib Could Extend Survival for Uterine Cancer Patients
FRIDAY, March 22, 2024 -- An already approved cancer drug could be an effective treatment for women with advanced, recurring uterine cancer, a new clinical trial shows.
Rucaparib, which belongs to a class of drugs called PARP inhibitors, extended... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - March 22, 2024 Category: General Medicine Source Type: news
Would you rather: quantifying TBI survivor perceptions of functional status via their surrogates - Maiga AW, Cook MR, Nordness MF, Gao Y, Rakhit S, Rivera EL, Harrell FEJ, Patel MB.
OBJECTIVE: To quantify health utilities of the Glasgow Outcome Scale-Extended (GOSE) states after actual Traumatic Brain Injury (TBI). BACKGROUND: Recovery after TBI is measured using the GOSE, a validated clinical trial endpoint. A recent public s... (Source: SafetyLit)
Source: SafetyLit - March 22, 2024 Category: International Medicine & Public Health Tags: TBI Source Type: news
Regulus Therapeutics Reports Fourth Quarter and Year-End 2023 Financial Results and Recent Updates
Positive topline data from the second cohort of patients in Phase 1b Multiple-Ascending Dose (MAD) Clinical Trial of RGLS8429 for the Treatment of Autosomal Dominant Polycystic Kidney Disease (ADPKD) Oversubscribed $100 million private placement; expected to extend cash runway into H1... (Source: PRWeb: Medical Pharmaceuticals)
Source: PRWeb: Medical Pharmaceuticals - March 21, 2024 Category: Pharmaceuticals Tags: ERN Source Type: news
Clinical Trial Sites: The Rise of the Mega Network, Upcoming Webinar Hosted by Xtalks
In this free webinar, learn about recent trends in clinical trial site network consolidation. Attendees will examine drivers and challenges for site network consolidation. The featured speakers will discuss the impact larger site networks will have on clinical trials. Attendees will learn... (Source: PRWeb: Medical Pharmaceuticals)
Source: PRWeb: Medical Pharmaceuticals - March 21, 2024 Category: Pharmaceuticals Tags: FVT Source Type: news
Remote CBT as Effective as In-Person CBT for Mental Illness Remote CBT as Effective as In-Person CBT for Mental Illness
Therapist-guided remote CBT is just as effective as in-person CBT for a range of mental health disorders, a new review of clinical trials showed.Medscape Medical News (Source: Medscape Psychiatry Headlines)
Source: Medscape Psychiatry Headlines - March 21, 2024 Category: Psychiatry Tags: Psychiatry Source Type: news
Experimental gene therapy for giant axonal neuropathy shows promise in NIH clinical trial
An investigational gene therapy for a rare neurodegenerative disease that begins in early childhood, known as giant axonal neuropathy (GAN), was well tolerated and showed signs of therapeutic benefit in a clinical trial led by the National Institutes of Health (NIH). Currently, there is no treatment for GAN and the disease is usually fatal by 30 years of age. Fourteen children with GAN, ages 6 to 14 years, were treated with gene transfer therapy at the NIH Clinical Center and then followed for about six years to assess safety. (Source: World Pharma News)
Source: World Pharma News - March 21, 2024 Category: Pharmaceuticals Tags: Featured Research Research and Development Source Type: news
Spinal Delivery of Gene Therapy Promising for Neurodegenerative Disease
(MedPage Today) -- Gene therapy delivered for the first time via lumbar puncture showed promise of benefit in slowing progression of giant axonal neuropathy (GAN) in a phase I clinical trial.
The slope of change in motor function went from -7... (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - March 21, 2024 Category: Neurology Source Type: news
Clinical trial results show new Penn technology could be the key to fighting brain cancer
Financed in part by Kite Pharma, the study of a new cell therapy technique developed at Penn yielded positive early results in brain cancer patients. (Source: bizjournals.com Health Care:Pharmaceuticals headlines)
Source: bizjournals.com Health Care:Pharmaceuticals headlines - March 21, 2024 Category: Pharmaceuticals Authors: John George Source Type: news
Experimental gene therapy for giant axonal neuropathy shows promise in NIH clinical trial
Treatment for rare childhood disease was well tolerated and slowed loss of motor function. (Source: National Institutes of Health (NIH) News Releases)
Source: National Institutes of Health (NIH) News Releases - March 20, 2024 Category: American Health Source Type: news
ARPA-H taps Pisano for'Advancing Clinical Trials Readiness' initiative
The Advanced Research Projects Agency for Health (ARPA-H) has tapped the American College of Radiology's (ACR) Chief Research Officer Etta Pisano, MD, to develop its clinical trial portfolio and lead its Advancing Clinical Trials Readiness initiative.
The ARPA-H is a new federal health research and development organization within the U.S. Department of Health and Human Services. Pisano is the first radiologist appointed to such a role in the ARPA-H, and she will lead the initiative under the agency's Resilient Systems Mission office director, Jennifer Roberts, PhD, according to a statement released by the ACR. In the posi...
Source: AuntMinnie.com Headlines - March 20, 2024 Category: Radiology Authors: Kate Madden Yee Tags: Practice Management Source Type: news
