Davis company working on breathable medicine to aid Covid-19 recovery
A Davis biopharmaceutical startup has licensed a breathable statin technology from the University of California Davis that may help people suffer less and recover faster from Covid-19. InVixa Inc. plans to be in preclinical trials starting this year for its breathable medicine, which gets into the nose and lungs more quickly than a pill and could treat the respiratory problems caused by viruses and specifically Covid-19. Human trials could begin this year. “Our initial focus will be to treat… (Source: bizjournals.com Health Care:Pharmaceuticals headlines)
Source: bizjournals.com Health Care:Pharmaceuticals headlines - January 19, 2021 Category: Pharmaceuticals Authors: Mark Anderson Source Type: news

Statins warning: Grapefruit juice could interact with the treatment - what else to avoid
STATINS are a group of medicines that can help reduce the amount of accumulated cholesterol in your blood. Statins can interact with certain dietary items so caution is advised. A surprising interaction is grapefruit. (Source: Daily Express - Health)
Source: Daily Express - Health - January 19, 2021 Category: Consumer Health News Source Type: news

Statins side effects: Four gastrointestinal symptoms warning something is not right
STATINS side effects: There are a variety of ailments which may ensue due to taking the medication. Experiencing any of these four gastrointestinal symptoms could be signs you need to see your GP. (Source: Daily Express - Health)
Source: Daily Express - Health - January 19, 2021 Category: Consumer Health News Source Type: news

Statins and Disease Recurrence in Ulcerated Primary Melanoma Statins and Disease Recurrence in Ulcerated Primary Melanoma
Might long-term statin use before melanoma diagnosis reduce the risk of melanoma recurrence?The British Journal of Dermatology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - January 19, 2021 Category: Consumer Health News Tags: Dermatology Journal Article Source Type: news

Statins: Do Statins cause more harm than good? What are the side effects?
STATINS are a type of medication that help to prevent high cholesterol levels in the blood as well as a number of deadly conditions, including heart disease, strokes, and heart attacks. But do statins cause more harm than good, and what are the side effects of taking statins? (Source: Daily Express - Health)
Source: Daily Express - Health - January 18, 2021 Category: Consumer Health News Source Type: news

New study identifies opposite roles of sugars and fat on cellular immunotherapy of cancer
(Instituto de Medicina Molecular) The team led by Bruno Silva Santos, Principal Investigator iMM, discovered that the functions of a subtype of white blood cells - gamma delta T cells - are regulated by metabolic resources, namely sugars and fat. The results now published in the scientific journal Nature Immunology, open new avenues for the use of sugar metabolism in gamma-delta T cells as an effective tool in cellular immunotherapy of cancer, in addition to building further on the concept that high cholesterol levels are a barrier to its effectiveness. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - January 18, 2021 Category: Cancer & Oncology Source Type: news

High cholesterol symptoms: Nodules on your Achilles tendon is a warning sign
HIGH cholesterol is highly pernicious because it raises your risk of heart disease and doesn't leave a trace. However, in rare instances, high cholesterol can give rise to some perceptible warning signs, including nodules on your Achilles tendons. (Source: Daily Express - Health)
Source: Daily Express - Health - January 17, 2021 Category: Consumer Health News Source Type: news

High cholesterol symptoms: The warning sign in your hearing that could signal high levels
HIGH cholesterol can hike your risk of having a heart attack so it is vital that you reduce high levels of the fatty substance. High cholesterol is usually symptomless but a sign in your ears bucks this trend. (Source: Daily Express - Health)
Source: Daily Express - Health - January 16, 2021 Category: Consumer Health News Source Type: news

High cholesterol can lead to deadly atherosclerosis - can the condition be reversed?
HIGH cholesterol refers to too much of the fatty substance in the bloodstream; it can clump together and settle on the artery walls. This narrowing of the arteries may lead to life-threatening health condition atherosclerosis. (Source: Daily Express - Health)
Source: Daily Express - Health - January 14, 2021 Category: Consumer Health News Source Type: news

Cryo-EM structure of the B cell co-receptor CD19 bound to the tetraspanin CD81
Signaling through the CD19-CD81 co-receptor complex, in combination with the B cell receptor, is a critical determinant of B cell development and activation. It is unknown how CD81 engages CD19 to enable co-receptor function. Here, we report a 3.8-angstrom structure of the CD19-CD81 complex bound to a therapeutic antigen-binding fragment, determined by cryo–electron microscopy (cryo-EM). The structure includes both the extracellular domains and the transmembrane helices of the complex, revealing a contact interface between the ectodomains that drives complex formation. Upon binding to CD19, CD81 opens its ectodomain ...
Source: ScienceNOW - January 14, 2021 Category: Science Authors: Susa, K. J., Rawson, S., Kruse, A. C., Blacklow, S. C. Tags: Biochemistry, Cell Biology reports Source Type: news

High cholesterol: The four physical symptoms felt on the body warning levels are too high
HIGH cholesterol: The body needs cholesterol to build healthy cells, but high levels of cholesterol can increase your risk of heart disease. What are the four physical symptoms warning your levels are dangerously high. (Source: Daily Express - Health)
Source: Daily Express - Health - January 12, 2021 Category: Consumer Health News Source Type: news

Foods That May Lead to a Healthier Gut and Better Health
A diet full of highly processed foods with added sugars and salt promoted gut microbes linked to obesity, heart disease and diabetes. (Source: NYT Health)
Source: NYT Health - January 11, 2021 Category: Consumer Health News Authors: Anahad O ’Connor Tags: Microbiology Research Digestive Tract Diet and Nutrition Obesity Weight Diabetes Heart Vegetables Cholesterol Health Foods Nature Medicine (Journal) Source Type: news

Statins May Protect Heart From Chemo for Early Breast Cancer
Risk for heart failure hospital presentations significantly lower in statin - exposed women treated with anthracyclines (Source: The Doctors Lounge - Oncology)
Source: The Doctors Lounge - Oncology - January 7, 2021 Category: Cancer & Oncology Tags: Cardiology, Gynecology, Oncology, Pharmacy, Journal, Source Type: news

Study reveals: Men should eat walnuts to prevent prostate cancer
(Natural News) Good news, gentlemen: Eating walnuts can help stave off prostate cancer. This is according to researchers from the University of California, Davis, who found that walnuts, aside from helping to reduce excess cholesterol and increasing insulin sensitivity, are also capable of reducing the levels of a protein associated with prostate cancer. According to nutritionist Paul Davis, who... (Source: NaturalNews.com)
Source: NaturalNews.com - January 7, 2021 Category: Consumer Health News Source Type: news

Early, Large LDL Reduction Tied to Lowest Event Rates After MI Early, Large LDL Reduction Tied to Lowest Event Rates After MI
Real-world evidence from the SWEDEHEART registry shows that larger early LDL-C reductions with high-intensity statins are associated with a host of benefits compared with smaller reductions.Medscape Medical News (Source: Medscape Med Students Headlines)
Source: Medscape Med Students Headlines - January 7, 2021 Category: Universities & Medical Training Tags: Cardiology News Source Type: news

Statins May Protect Heart From Chemo for Early Breast Cancer
THURSDAY, Jan. 7, 2021 -- For women with early breast cancer treated with anthracyclines, statin exposure is associated with a lower risk for hospital presentation for heart failure, according to a study published online Jan. 6 in the Journal of the... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - January 7, 2021 Category: Pharmaceuticals Source Type: news

Statins May Give Boost to Mesothelioma Immunotherapy Drugs
This study, which included both patients with pleural mesothelioma and with advanced non-small cell lung cancer, found a potential synergy with the immunotherapy drugs. Opdivo and Keytruda, generically called nivolumab and pembrolizumab, respectively, are known as PD-1 inhibitors, drugs that restrict a protein from stopping immune response to cancer cells. “Statins may lead to prolonged antigen retention on cell membrane and strengthen antigen presentation to T cells, thus suggesting a potential synergy with PD-1 inhibitors,” the authors wrote. “The anti-tumor effect of statins might be attributed to an i...
Source: Asbestos and Mesothelioma News - January 7, 2021 Category: Environmental Health Authors: Fran Mannino Source Type: news

New Data Strengthen Case for Prechemotherapy Statins New Data Strengthen Case for Prechemotherapy Statins
Statins were linked to a roughly 50% reduction in heart failure hospitalizations among older patients with breast cancer, including those given anthracyclines.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - January 7, 2021 Category: Cancer & Oncology Tags: Cardiology News Source Type: news

High cholesterol warning: Psoriasis symptoms could be a visual sign of high cholesterol
HIGH CHOLESTEROL can increase your risk of heart and circulatory diseases so it is vital to lower your levels. The condition doesn't usually present any warning signs but a study suggests psoriasis symptoms may signal you have too much cholesterol in your blood. (Source: Daily Express - Health)
Source: Daily Express - Health - January 6, 2021 Category: Consumer Health News Source Type: news

How to live longer: Ginger tea may hold anti-cancer properties to help boost longevity
HOW TO live longer: Tea infused with ginger contains powerful properties to help lower cholesterol, reduce cancer risk and alleviate pain in joints - all of which could help boost longevity. (Source: Daily Express - Health)
Source: Daily Express - Health - January 6, 2021 Category: Consumer Health News Source Type: news

Common drug may protect hearts from damage caused by breast cancer chemotherapy
(University Health Network) New research from UHN's Peter Munk Cardiac Centre (PMCC) shows statins, commonly prescribed to lower cholesterol and reduce the risk of heart disease and stroke, may also protect the heart from damaging side-effects of early breast cancer treatment. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - January 6, 2021 Category: International Medicine & Public Health Source Type: news

Statins may protect the heart from chemotherapy treatment of early breast cancer
(American Heart Association) Women who take statins, the common cholesterol-lowering medication, during chemotherapy with anthracyclines for early-stage breast cancer are half as likely to require emergency department visits or hospitalization for heart failure in the 5 years after chemotherapy. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - January 6, 2021 Category: International Medicine & Public Health Source Type: news

Falk lecture — endoplasmic reticulum and metabolism, immunity, health
In the annual Falk lecture, Gokhan Hotamisligil discussed the endoplasmic reticulum’s role in sensing and responding to cholesterol levels. (read more) (Source: Environmental Factor - NIEHS Newsletter)
Source: Environmental Factor - NIEHS Newsletter - January 6, 2021 Category: Environmental Health Source Type: news

How to live longer: Kimchi shown to lower high blood pressure and high cholesterol
HOW TO live longer: The surest path to longevity lies in judicious dietary decisions. Fermented foods have come under the spotlight for their positive health effects. At the front of the pack is kimchi. (Source: Daily Express - Health)
Source: Daily Express - Health - January 5, 2021 Category: Consumer Health News Source Type: news

What Is the Normal Range for Cholesterol Levels?
Title: What Is the Normal Range for Cholesterol Levels?Category: Diseases and ConditionsCreated: 1/5/2021 12:00:00 AMLast Editorial Review: 1/5/2021 12:00:00 AM (Source: MedicineNet Cholesterol General)
Source: MedicineNet Cholesterol General - January 5, 2021 Category: Cardiology Source Type: news

Neurobiology of impulsivity and aggression as substrates of suicidal behavior: a narrative focus on the involvement of serum lipids - Gokcay H, Balcioglu Y.
Previous incidental findings of an increase of suicidal risk among subjects with low cholesterol levels have drawn attention to the role of lipids in suicidal behavior. To date, multiple lines of evidence acquired from clinical studies have confirmed an as... (Source: SafetyLit)
Source: SafetyLit - January 4, 2021 Category: International Medicine & Public Health Tags: Ergonomics, Human Factors, Anthropometrics, Physiology Source Type: news

Does Coconut Oil Deserve Its Health Halo?
“It’s been known for a long time that coconut oil raises blood levels of artery-damaging LDL cholesterol,” one expert said. (Source: NYT Health)
Source: NYT Health - January 4, 2021 Category: Consumer Health News Authors: Jane E. Brody Tags: Cholesterol Coconuts Oils and Fats Heart Diet and Nutrition Advertising and Marketing Source Type: news

What Does It Mean to Have Hyperlipidemia?
Title: What Does It Mean to Have Hyperlipidemia?Category: Diseases and ConditionsCreated: 1/4/2021 12:00:00 AMLast Editorial Review: 1/4/2021 12:00:00 AM (Source: MedicineNet Cholesterol General)
Source: MedicineNet Cholesterol General - January 4, 2021 Category: Cardiology Source Type: news

A fat molecule unique to avocados can help lower diabetes risk by addressing insulin resistance
(Natural News) Avocados are a powerful superfood that confers a host of health benefits. They help lower cholesterol levels, improve nutrient absorption and promote weight loss. Studies also show that avocados can help prevent cancer and relieve osteoarthritis symptoms. However, the compounds in avocados responsible for these health benefits are still unidentified. In 2015, researchers discovered a compound unique... (Source: NaturalNews.com)
Source: NaturalNews.com - December 29, 2020 Category: Consumer Health News Source Type: news

High cholesterol: Magnesium or green tea extract supplements could help lower your levels
HIGH cholesterol is an insidious condition whereby the sufferer remains completely oblivious to the dangers that lies deep within. Left untreated though and serious health risks will ensue. By taking either magnesium or green tea extract supplements your levels can be greatly lowered. (Source: Daily Express - Health)
Source: Daily Express - Health - December 29, 2020 Category: Consumer Health News Source Type: news

To Prescribe or Deprescribe Statins, That Is the Question
The treatment of elevated cholesterol, particularly with β-hydroxy β-methylglutaryl-CoA (HMG-CoA) reductase inhibitors, commonly known as statins, is measured by the Centers for Medicare& Medicaid Services in various different ways. Statin Use in Persons With Diabetes (SUPD), a new Medicare Part D star measure in 2019, was listed as measure D14 in 2020; it calculates the percentage of patients between 40 and 75 years old who received at least two diabetes medication fills and also received a statin medication during the measurement period. (Source: Caring for the Ages)
Source: Caring for the Ages - December 29, 2020 Category: Health Management Authors: Jeanne Manzi Source Type: news

Large transporter protein linked to schizophrenia
(Kyoto University) Scientists have suspected mutations in a cellular cholesterol transport protein are associated with psychiatric disorders, but have found it difficult to prove this and to pinpoint how it happens. Now, Kazumitsu Ueda of Kyoto University's Institute for Integrated Cell-Material Sciences (iCeMS) and colleagues in Japan have provided evidence that mice with disrupted ABCA13 protein demonstrate a hallmark behaviour of schizophrenia. The team investigated ABCA13's functions and published their findings in theJournal of Biological Chemistry. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - December 29, 2020 Category: International Medicine & Public Health Source Type: news

Fathers Health Tied to Pregnancy Loss
Conditions like hypertension, high cholesterol, obesity and diabetes in a father may affect whether a pregnancy reaches full term. (Source: NYT Health)
Source: NYT Health - December 23, 2020 Category: Consumer Health News Authors: Nicholas Bakalar Tags: Pregnancy and Childbirth Men and Boys Human Reproduction (Journal) Source Type: news

What Reduces Cholesterol Quickly?
Title: What Reduces Cholesterol Quickly?Category: Diseases and ConditionsCreated: 12/23/2020 12:00:00 AMLast Editorial Review: 12/23/2020 12:00:00 AM (Source: MedicineNet High Blood Pressure General)
Source: MedicineNet High Blood Pressure General - December 23, 2020 Category: Cardiology Source Type: news

Novartis Receives FDA Complete Response Letter on Inclisiran Novartis Receives FDA Complete Response Letter on Inclisiran
The FDA was unable to approve the new drug application for inclisiran, a novel treatment to lower LDL cholesterol, owing to unresolved facility inspection concerns, the company said.News Alerts (Source: Medscape Cardiology Headlines)
Source: Medscape Cardiology Headlines - December 22, 2020 Category: Cardiology Tags: Cardiology News Source Type: news

High cholesterol: Extreme fatigue could indicate your levels are dangerously high
HIGH cholesterol: Cholesterol is needed in the body to help function effectively however having too much of it can increase your risk of a heart attack or stroke. Extreme fatigue is a lesser-known warning sign of the condition. (Source: Daily Express - Health)
Source: Daily Express - Health - December 21, 2020 Category: Consumer Health News Source Type: news

AHA 2020 Highlights: Potential Practice Changers AHA 2020 Highlights: Potential Practice Changers
AHA provided some answers to the perplexing issues of statin myopathy and MINOCA. There were also some clever implementation science studies.theheart.org on Medscape (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - December 17, 2020 Category: Consumer Health News Tags: Cardiology News Source Type: news

Fish oil supplements don't raise bad cholesterol
(Wright On Marketing& Communications) The Fatty Acid Research Institute (FARI) has published a new research paper in conjunction with The Cooper Institute on the omega-3s EPA and DHA in fish oil and low density lipoprotein cholesterol (LDL-C). (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - December 17, 2020 Category: Biology Source Type: news

One in Five Patients Hospitalized With COVID - 19 Dies
Statins, angiotensin - converting enzyme inhibitors, and calcium channel blockers tied to lower risk for death (Source: Pulmonary Medicine News - Doctors Lounge)
Source: Pulmonary Medicine News - Doctors Lounge - December 16, 2020 Category: Respiratory Medicine Tags: Infections, Internal Medicine, Critical Care, Emergency Medicine, Nephrology, Nursing, Pathology, Pharmacy, Pulmonology, Geriatrics, Journal, Source Type: news

New in the < i > Hastings Center Report < /i > , November-December 2020
(The Hastings Center) Appealing to patient autonomy, bioethicists argue for making oral contraceptives, HIV-prevention medicines, statins, and many other prescription drugs available over the counter. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - December 16, 2020 Category: International Medicine & Public Health Source Type: news

Top Cardiology Trials of 2020 in Review Top Cardiology Trials of 2020 in Review
The annual tradition continues as did cardiology research despite a pandemic. Trials on fish oils, statins, SGLT2 inhibitors, and antiplatelets are among the selections of Drs Harrington and Gibson.theheart.org on Medscape (Source: Medscape Cardiology Headlines)
Source: Medscape Cardiology Headlines - December 15, 2020 Category: Cardiology Tags: Cardiology Expert Interview Source Type: news

American College of Cardiology to collaborate with Amgen, Veradigm to optimize ACS Care
(American College of Cardiology) The American College of Cardiology, in collaboration with Amgen and Veradigm, today announced a new national study to transform care for acute coronary syndrome (ACS) patients at risk for future cardiovascular events. TRANSFORM: Accelerating Lipid Lowering Post ACS (TRANSFORM: ACS) will ensure ACS patients quickly receive cholesterol testing in the hospital and guideline-recommended therapies to reduce LDL cholesterol in the hospital and upon discharge. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - December 15, 2020 Category: International Medicine & Public Health Source Type: news

LDL Not the Primary Culprit in ASCVD? LDL Not the Primary Culprit in ASCVD?
LDL cholesterol has been seen as the main offender in ASCVD, but new studies implicate other lipids, including so-called"remnant" cholesterol. An editorial, however, urges caution in interpretation.Medscape Medical News (Source: Medscape Cardiology Headlines)
Source: Medscape Cardiology Headlines - December 15, 2020 Category: Cardiology Tags: Cardiology News Source Type: news

High cholesterol: The four natural ways you can lower your levels
HIGH cholesterol belongs to a club of conditions that contribute to heart disease. Fortunately, your levels can be lowered by adding more flaxseeds, fibre, artichokes and reducing your trans-fat. (Source: Daily Express - Health)
Source: Daily Express - Health - December 12, 2020 Category: Consumer Health News Source Type: news

Cardiometabolic Traits, Sepsis, and Severe COVID-19: A Mendelian Randomization Investigation
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for the current coronavirus disease 2019 (COVID-19) pandemic. Many patients with severe COVID-19 develop sepsis. Cardiometabolic traits have been associated with increased risk of severe COVID-19 and sepsis; however, it is difficult to infer causal effects from observational studies because of the possibility that any identified associations may be attributable to confounding. Here, we leverage data from large-scale genetic association studies to identify genetic proxies for body mass index (BMI), lifetime smoking score, low-density lipoprotein cho...
Source: Current Awareness Service for Health (CASH) - December 10, 2020 Category: Consumer Health News Source Type: news

Relationship between risk markers for cardiovascular disease and peri-implant diseases
ConclusionHigh levels of triglyceride and uric acid may pose a risk for both peri-implant diseases and cardiovascular diseases. Prior to dental implant surgery, patients ’ serum biochemical parameters should be checked. (Source: Dental Technology Blog)
Source: Dental Technology Blog - December 9, 2020 Category: Dentistry Source Type: news

Can you have the coronavirus vaccine if you're on statins?
STATIN prescriptions form a part of many people's daily routines, especially older people in the UK, many of whom will soon have their first dose of the Covid vaccine. Can you have the coronavirus vaccine if you're on statins? (Source: Daily Express - Health)
Source: Daily Express - Health - December 9, 2020 Category: Consumer Health News Source Type: news

' Suboptimal' Primary CVD Prevention for Sexual Minorities'Suboptimal' Primary CVD Prevention for Sexual Minorities
Cholesterol-lowering medications are indicated for primary prevention of cardiovascular disease, but are underprescribed in sexual minorities.Medscape Medical News (Source: Medscape Cardiology Headlines)
Source: Medscape Cardiology Headlines - December 9, 2020 Category: Cardiology Tags: Psychiatry News Source Type: news

How blood and wealth can predict future disability
(University of East Anglia) Research shows that blood tests for biomarkers such as cholesterol and inflammation can predict disability in five years.Researchers studied blood biomarkers of 5,286 participants involved in the UK Household Longitudinal Study - and found that biological health can predict disability and healthcare demand in five years' time.They also found that people on higher-incomes were more likely to seek GP appointments and outpatient treatments for their medical problems. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - December 9, 2020 Category: International Medicine & Public Health Source Type: news