Sex differences in autoimmune disorders and schizophrenia
A new study suggests that an immune-related protein found in higher levels in men helps protect against certain autoimmune diseases but increases the risk of schizophrenia. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - May 19, 2020 Category: Consumer Health News Source Type: news

Repurposed drug combats obesity in mice
Obese mice lost weight and showed improved metabolic function when treated with a drug that ’s normally prescribed for alcohol use disorder. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - May 19, 2020 Category: Consumer Health News Source Type: news

Llama antibody engineered to block coronavirus
Based on antibodies isolated from llamas, researchers engineered an antibody that prevented SARS-CoV-2, the virus that causes COVID-19, from entering cells in laboratory experiments. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - May 18, 2020 Category: Consumer Health News Source Type: news

Robotic screening speeds testing of oral drugs
A robotic system to rapidly test the absorption of drugs in the small intestine could help speed the development and testing of oral medications. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - May 5, 2020 Category: Consumer Health News Source Type: news

New genetic regions linked to risk of melanoma
Researchers linked new regions of the genome to melanoma, the deadliest form of skin cancer, suggesting new avenues to explore for a better understanding of the disease. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - May 5, 2020 Category: Consumer Health News Source Type: news

Poor sleep linked with higher blood sugar levels in African Americans
African American men and women who had severe sleep apnea or other disrupted sleep patterns had higher blood sugar levels than those who slept normally. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - May 4, 2020 Category: Consumer Health News Source Type: news

Blocking enzyme inhibits arthritis progression in mice
Blocking an enzyme called TET1 protected mice against the development of osteoarthritis and cells from people with osteoarthritis from gene changes that help drive the disease. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - April 28, 2020 Category: Consumer Health News Source Type: news

Lab-made eye cells restore vision in mice
Researchers reprogrammed skin cells into light-sensing eye cells that restored sight in mice. The technique may lead to new approaches for modeling and treating eye diseases. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - April 28, 2020 Category: Consumer Health News Source Type: news

Infant temperament predicts introversion in adulthood
A study highlighting the enduring nature of early temperament suggests ways to identify those most at risk for developing anxiety and depression later in life. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - April 27, 2020 Category: Consumer Health News Source Type: news

Dopamine modification on chromatin linked to addiction
Researchers found that dopamine can modify the structure that DNA is packed into and alter gene expression following cocaine exposure. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - April 21, 2020 Category: Consumer Health News Source Type: news

Marker of autoimmunity increases in U.S.
Autoimmunity may be on the rise, based on a study of antinuclear antibodies in blood samples collected nationwide from 1988-2012. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - April 21, 2020 Category: Consumer Health News Source Type: news

Drop in coal power plant emissions associated with asthma improvements
Reductions in sulfur dioxide emissions from coal-fired power plants were associated with fewer local hospitalizations and emergency department visits due to asthma. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - April 20, 2020 Category: Consumer Health News Source Type: news

Blocking cellular receptor stops spread of tau in mouse brains
In experiments in cells and mice, blocking a protein called LPR1 stopped both normal and harmful forms of tau, which are involved in dementias, from spreading between neurons. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - April 14, 2020 Category: Consumer Health News Source Type: news

Gene linked to sex differences in autism
Researchers found that a small cluster of mutations in the NLGN4X gene, which has been linked to autism spectrum disorder, may explain the sex differences tied to the gene. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - April 14, 2020 Category: Consumer Health News Source Type: news

Microneedle coronavirus vaccine triggers immune response in mice
When delivered to mice using microneedles, an experimental vaccine for COVID-19 caused antibody production against the disease within two weeks. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - April 9, 2020 Category: Consumer Health News Source Type: news

3D-printed scaffold engineered to grow complex tissues
A new technique to engrave 3D-printed scaffolds could be used to boost the repair of complex tissues with different types of cells, such as bone and cartilage. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - April 7, 2020 Category: Consumer Health News Source Type: news

Comparing heart disease treatments
For patients with heart disease, invasive procedures showed similar reductions in the risk of heart attack and death to medication and lifestyle changes alone. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - April 7, 2020 Category: Consumer Health News Source Type: news

Diets improve but remain poor for most U.S. children
Although diet quality improved modestly for American children and adolescents from 1999 to 2016, more than half still had poor quality diets. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - April 6, 2020 Category: Consumer Health News Source Type: news

Technique reveals organization of tongue bacteria
Using advanced imaging techniques, researchers revealed how different bacteria live together in communities on the human tongue. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - March 31, 2020 Category: Consumer Health News Source Type: news

Dopamine affects how brain decides whether a goal is worth the effort
Researchers found that drugs like Ritalin may work as a study aid by shifting attention, through the brain chemical dopamine, from the challenges of undertaking a difficult mental task to its rewards. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - March 31, 2020 Category: Consumer Health News Source Type: news

Number of steps per day more important than step intensity
Adults who took 8,000 or more steps a day had a reduced risk of death over the following decade than those who only walked 4,000 steps a day. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - March 30, 2020 Category: Consumer Health News Source Type: news

Insights into skin formation
Researchers discovered how distinct liquid droplets within cells help build the skin ’s outer layer. The study may lead to a better understanding of conditions like atopic dermatitis and psoriasis. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - March 24, 2020 Category: Consumer Health News Source Type: news

Spinal nerve healing enhanced by boost in cellular energy
Mice engineered to lack a protein that anchors mitochondria in injured nerve cells showed regrowth of those cells after a spinal cord injury. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - March 24, 2020 Category: Consumer Health News Source Type: news

Study suggests new coronavirus may remain on surfaces for days
Scientists found that SARS-CoV-2, the virus that causes COVID-19, can be detected in aerosols for up to three hours and on plastic and stainless steel surfaces for up to three days. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - March 23, 2020 Category: Consumer Health News Source Type: news

Combining tests more accurately diagnoses prostate cancer
Adding MRI-targeted biopsies to the traditional prostate biopsy created a more accurate diagnosis and prediction of the course of prostate cancer. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - March 17, 2020 Category: Consumer Health News Source Type: news

Memories involve replay of neural firing patterns
Researchers found that the distinct firing patterns of individual neurons that the brain uses when forming memories are replayed when remembering the experience. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - March 17, 2020 Category: Consumer Health News Source Type: news

Artificial intelligence predicts heart disease risk from CT scans
Artificial intelligence-based analysis of CT scans predicted people ’s risk of heart disease more accurately than current methods. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - March 17, 2020 Category: Consumer Health News Source Type: news

Combining tests more accurately diagnoses prostate cancer
Adding MRI-targeted biopsies to the traditional prostate biopsy created a more accurate diagnosis and prediction of the course of prostate cancer. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - March 16, 2020 Category: Consumer Health News Source Type: news

Bone-building protein delivered orally to mice using plants
Diabetic mice fed plants that were engineered to carry a bone-building protein showed accelerated healing of bone fractures. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - March 10, 2020 Category: Consumer Health News Source Type: news

Irregular sleep patterns may raise risk of heart disease
Researchers found that irregular sleep patterns —varying the timing and amount of sleep—may increase the risk of developing cardiovascular disease in people ages 45 to 84. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - March 10, 2020 Category: Consumer Health News Source Type: news

New blood test method may predict Alzheimer's disease
A blood testing technique to detect Alzheimer ’s disease could enable earlier treatments and testing of novel approaches. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - March 9, 2020 Category: Consumer Health News Source Type: news

Neurons play role in oral cancer
Scientists discovered a new role for nerves in oral cancer progression, in which tumor cells send genetic messages that transform nerves into cancer-promoting agents. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - February 25, 2020 Category: Consumer Health News Source Type: news

Test distinguishes Parkinson ’s disease from related condition
A test that uses samples of cerebrospinal fluid was able to distinguish Parkinson ’s disease from a related condition called multiple system atrophy with 95% accuracy. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - February 25, 2020 Category: Consumer Health News Source Type: news

Neural signature predicts antidepressant response
Researchers identified specific patterns of brain activity that predict whether someone with depression is likely to respond to a common antidepressant. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - February 24, 2020 Category: Consumer Health News Source Type: news

Engineered bacteria protect honey bee health
Bacteria naturally found in honey bees were engineered to help bees fight infections that that have been destroying colonies. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - February 11, 2020 Category: Consumer Health News Source Type: news

Genes linked to schizophrenia identified in ancestral African population
Researchers found damaging genetic variants linked to schizophrenia in the Xhosa population of South Africa. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - February 11, 2020 Category: Consumer Health News Source Type: news

Low-dose aspirin reduces preterm birth among first-time mothers
In a large trial, daily low-dose aspirin reduced the risk of preterm birth (before 37 weeks) by 11% and early preterm birth (before 34 weeks) by 25% among first-time mothers. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - February 10, 2020 Category: Consumer Health News Source Type: news

New strategies drive HIV from cellular hiding places
Experimental treatments in animal models of HIV led to the viruses emerging from their hiding places, a first step needed to make HIV vulnerable to the immune system. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - February 4, 2020 Category: Consumer Health News Source Type: news

Drug activates brown fat, improves glucose metabolism in healthy women
In a small study, a drug approved to treat overactive bladder boosted brown fat activity and improved glucose metabolism in healthy women. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - February 4, 2020 Category: Consumer Health News Source Type: news

How stress causes gray hair
Stress can cause hair to gray prematurely by affecting the stem cells that are responsible for regenerating hair pigment, researchers found. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - February 3, 2020 Category: Consumer Health News Source Type: news

Mother ’s gut microbes may influence offspring’s immunity
A study in mice showed how that a mother ’s gut bacteria can induce antibodies that protect newborns against diarrheal disease. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - January 28, 2020 Category: Consumer Health News Source Type: news

Predicting Alzheimer ’s disease progression
A study suggested that PET imaging of tau tangles in the brain could be a way to track development of Alzheimer ’s disease, predict loss of brain tissue, and assess new treatments. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - January 28, 2020 Category: Consumer Health News Source Type: news

Alcohol-related deaths increasing nationwide
An analysis of U.S. death certificate data showed that alcohol-related deaths increased among people in almost all age and racial and ethnic groups between 1999 and 2017. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - January 24, 2020 Category: Consumer Health News Source Type: news

Understanding allergic reactions to skin care products
A laboratory study gave new insight into how skin creams, cosmetics, and fragrances may cause immune responses that lead to rashes in some people. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - January 14, 2020 Category: Consumer Health News Source Type: news

Exposure to common insecticides associated with risk of death
People with higher exposures to common insecticides called pyrethroids had an increased risk of death in the years following the measurements. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - January 14, 2020 Category: Consumer Health News Source Type: news

Old TB vaccine may work better when delivered intravenously
Delivering the only approved tuberculosis vaccine intravenously greatly enhanced its ability to protect rhesus monkeys from infection. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - January 13, 2020 Category: Consumer Health News Source Type: news

Immune cell metabolism altered in ME/CFS
Scientists found that some immune cells in people with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) show disruptions in the way they produce and use energy. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - January 7, 2020 Category: Consumer Health News Source Type: news

Blood protein signatures change across lifespan
Blood levels of around 400 proteins accurately reflected people ’s age and relative health. Such a protein signature might help identify people at greater risk of age-related diseases. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - January 7, 2020 Category: Consumer Health News Source Type: news

Researchers find cause of new autoinflammatory disease
Researchers found that mutations in a specific gene cause a previously unknown autoinflammatory disease, which they ’ve named CRIA syndrome. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - January 6, 2020 Category: Consumer Health News Source Type: news

2019 Research Highlights — Basic Research Insights
Noteworthy NIH advances in basic research include evidence linking enterovirus infections with acute flaccid myelitis, insights into how disrupted sleep may lead to heart disease, and nanoparticle robots that sweep away biofilms. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - December 18, 2019 Category: Consumer Health News Source Type: news