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High-salt diet affects the brains of mice
A high-salt diet caused changes in the guts of mice that led to reduced blood flow in the brain and impaired cognition. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - February 6, 2018 Category: Consumer Health News Source Type: news

Early childhood program linked to higher education levels
Adults who participated in an extensive early childhood education program for children from low-income families attained higher educational levels than those who ’d received other interventions. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - February 6, 2018 Category: Consumer Health News Source Type: news

Physical clot removal can help more people after stroke
A brain imaging study identified people who can benefit from a clot-removing procedure for up to 16 hours after a stroke occurs, significantly expanding the treatment window. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - February 5, 2018 Category: Consumer Health News Source Type: news

Altered lung structure may increase COPD risk
A study found a link between variations in the structure of the lung ’s airways and the risk of developing chronic obstructive pulmonary disorder, or COPD. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - January 30, 2018 Category: Consumer Health News Source Type: news

Stem cell transplant helps people with severe scleroderma
A study of people with severe scleroderma found that a new approach using stem cell transplants provides a better outcome than an immune-suppressing drug. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - January 23, 2018 Category: Consumer Health News Source Type: news

Monitoring bacteria in the body with ultrasound
Researchers engineered genes that allowed them to detect bacteria in the bodies of mice. The technique could allow tracking of bacteria used in treatments for gut infections and cancer. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - January 23, 2018 Category: Consumer Health News Source Type: news

Does infant formula affect development of type 1 diabetes?
Results from a new study suggest no change in current guidelines for formula feeding in infants who are at risk for type 1 diabetes. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - January 23, 2018 Category: Consumer Health News Source Type: news

Technique treats hereditary deafness in mice
Researchers developed a genome editing strategy to treat hearing loss in a mouse model of hereditary deafness. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - January 9, 2018 Category: Consumer Health News Source Type: news

Air pollution linked to risk of premature death
A comprehensive analysis found that even short-term exposures to air pollution may have an impact on the health of older adults. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - January 9, 2018 Category: Consumer Health News Source Type: news

Factors contributing to higher incidence of diabetes for black Americans
A study found that biological risk factors —including weight and fat around the abdomen—are primarily responsible for the elevated rate of diabetes for black Americans. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - January 8, 2018 Category: Consumer Health News Source Type: news

2017 Research Highlights — Insights from the Lab
Noteworthy NIH advances in basic research include a 3-D model of human brain development and disease, a virus linked to food sensitivity, and a new role discovered for the thalamus. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - December 19, 2017 Category: Consumer Health News Source Type: news

2017 Research Highlights — Promising Medical Advances
NIH findings with potential for enhancing human health include understanding how dietary factors influence disease risk, combatting the epigenetic effects of outdoor air pollution, and methods to detect prions in blood and skin. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - December 19, 2017 Category: Consumer Health News Source Type: news

2017 Research Highlights — Clinical Advances
NIH accomplishments in the prevention, diagnosis, and treatment of human disease. These include progress on two Ebola vaccines, a bionic pancreas to treat type 1 diabetes, and a genetic test that improves blood thinner dosing. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - December 15, 2017 Category: Consumer Health News Source Type: news

Dietary fats influence endoplasmic reticulum membrane
A lab study may help explain on the molecular level why saturated fat can harm cells and unsaturated fat can be protective. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - December 12, 2017 Category: Consumer Health News Source Type: news

Unexplained cases of anaphylaxis linked to red meat allergy
Researchers identified the cause of some patients ’ repeated episodes of anaphylaxis: a red meat allergy that’s linked to a specific type of tick bite. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - December 12, 2017 Category: Consumer Health News Source Type: news

HIV prevention approach reduces new infections in Ugandan district
HIV prevention measures substantially reduced new HIV infections in a district of Uganda during a seven-year period. The results prove the approach can reduce new HIV infections. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - December 11, 2017 Category: Consumer Health News Source Type: news

Changing gut bacteria in Crohn ’s disease
A single enzyme altered the mix of bacteria in the guts of mice and led to inflammatory bowel disease. The study suggests a potential treatment target for diseases such as Crohn ’s disease and ulcerative colitis. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - December 5, 2017 Category: Consumer Health News Source Type: news

Prions found in skin of people with Creutzfeldt-Jakob disease
Researchers detected abnormal prion proteins in the skin of people who died from Creutzfeldt-Jakob disease. The results suggest that skin samples might be used to detect prion disease. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - December 5, 2017 Category: Consumer Health News Source Type: news

Improving walking for people with peripheral artery disease
A study of older adults with peripheral artery disease showed that treadmill exercise for 12 weeks improved walking distance, but a drug called GM-CSF did not. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - December 4, 2017 Category: Consumer Health News Source Type: news

Brain circuits linked to alertness
Researchers discovered brain circuits that regulate alertness in fish and mice. The findings could lead to a better understanding of mental health conditions associated with alertness. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - November 21, 2017 Category: Consumer Health News Source Type: news

How storing corneas affects transplantation success
A large study found that corneas can be stored safely for up to 11 days. The findings suggest that more people can have access to vision-saving corneal transplantations. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - November 21, 2017 Category: Consumer Health News Source Type: news

Physical activity key to keeping weight off
A careful metabolic analysis of contestants in “The Biggest Loser” competition supports previous findings that increased physical activity is key to keeping weight off. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - November 20, 2017 Category: Consumer Health News Source Type: news

CRISPR technology adapted to edit RNA
Researchers designed a highly specific RNA editing system based on the CRISPR/Cas gene editing technology. The study suggests a potential alternative to gene therapy. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - November 7, 2017 Category: Consumer Health News Source Type: news

Brain activity ripples linked to creation of long-term memories
A study in lab animals showed that communication between two brain regions may be needed for the formation of long-term memories. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - November 7, 2017 Category: Consumer Health News Source Type: news

Machine learning identifies suicidal youth
Researchers used machine learning to analyze brain images and identify people with suicidal thoughts. The approach could be used to assess suicide risk and monitor response to treatments. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - November 6, 2017 Category: Consumer Health News Source Type: news

Experience shapes mouse fighting and mating behaviors
Scientists identified brain activity that influences how a mouse responds when it meets an intruder mouse, a response that was once thought to be purely instinctive. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - October 31, 2017 Category: Consumer Health News Source Type: news

Hydrogel-grown tissues speed wound healing in mouse colon
An injectable hydrogel grew intestine-like tissues and accelerated wound healing in the intestines of mice. The findings suggest new treatments for diseases such as inflammatory bowel disease. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - October 31, 2017 Category: Consumer Health News Source Type: news

Structure guides design of dopamine receptor binding compound
The structure of a brain receptor for dopamine guided the design of a compound that activates it specifically. The approach could lead to psychiatric drugs with fewer side effects. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - October 30, 2017 Category: Consumer Health News Source Type: news

How too little potassium may contribute to cardiovascular disease
In mouse studies, scientists found a mechanism that may explain why low levels of potassium in the diet have been linked to high blood pressure, heart disease, and stroke in people. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - October 24, 2017 Category: Consumer Health News Source Type: news

Engineering malaria resistance in mosquitoes
Mosquitoes genetically modified to resist the parasite that causes malaria mated with wild mosquitoes and transferred the resistance to offspring in laboratory experiments. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - October 24, 2017 Category: Consumer Health News Source Type: news

Blocking stomach acid may promote chronic liver disease
A new study suggests that some widely used acid reflux (heartburn) medications may worsen chronic liver disease. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - October 23, 2017 Category: Consumer Health News Source Type: news

Mechanisms of age-related bone loss
Experiments in mice revealed mechanisms that may help explain why bones become weaker in older adults. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - October 17, 2017 Category: Consumer Health News Source Type: news

Brain cleaning system uses lymphatic vessels
Researchers discovered that our brains may drain waste out through lymphatic vessels, the body ’s sewer system. They could be a pipeline between the brain and the immune system. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - October 17, 2017 Category: Consumer Health News Source Type: news

Progress on two Ebola vaccines
Two test vaccines for Ebola were safe and induced lasting immune responses in a study with 1,500 adults in Liberia. The findings are an important step in development of a vaccine. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - October 16, 2017 Category: Consumer Health News Source Type: news

Engineered antibody protects monkeys from HIV-like virus
A “three-in-one” antibody made in the laboratory protected monkeys from infection with an HIV-related virus. Plans are under way to test the antibody in people. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - October 3, 2017 Category: Consumer Health News Source Type: news

Microneedle patch shrinks fat tissue in mice
In a proof-of-concept study in mice, a skin patch delivered a drug to convert white fat to calorie-burning brown fat. The approach could lead to new treatments for obesity and diabetes. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - October 3, 2017 Category: Consumer Health News Source Type: news

Genetic testing improves blood thinner dosing
Researchers found that genetics-based dosing for the blood thinner warfarin reduces the risk of major side effects in older patients starting the medication. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - October 2, 2017 Category: Consumer Health News Source Type: news

Immune cell-related proteins may speed healing after stroke
Two proteins associated with immune cells may play critical roles in helping the brain to heal after a stroke. The findings might one day lead to new treatments for stroke. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - September 26, 2017 Category: Consumer Health News Source Type: news

Calorie restriction slows age-related epigenetic changes
Researchers found that calorie restriction slows age-related epigenetic changes in mice and monkeys. The findings suggest a mechanism for how calorie restriction extends lifespan. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - September 26, 2017 Category: Consumer Health News Source Type: news

Infant exposure to pet and pest allergens may reduce asthma risk
Children exposed to high indoor levels of pet or pest allergens during infancy had a lower risk of developing asthma by age 7. The findings may inform strategies to prevent asthma. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - September 25, 2017 Category: Consumer Health News Source Type: news

Drugs extend healthy lifespan in mice
Researchers identified a novel class of drug that delayed several age-related symptoms in mice. The approach may help find compounds with potential to extend healthy life. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - September 12, 2017 Category: Consumer Health News Source Type: news

Blocking the pathway to HIV-related cardiovascular risks
Researchers identified a pathway that explains the link between HIV infection and cardiovascular events. An experimental drug blocked the pathway in monkeys. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - September 12, 2017 Category: Consumer Health News Source Type: news

Robotic device aids walking in children with cerebral palsy
In a small study with children who have a disorder from cerebral palsy known as crouch gait, researchers showed that a wearable robotic exoskeleton improved the ability to walk. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - September 11, 2017 Category: Consumer Health News Source Type: news

Insights into how female embryos develop
Studies in mice overturn the belief that embryos automatically become female unless androgens make them male. The findings may help advance studies of sexual development disorders. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - August 29, 2017 Category: Consumer Health News Source Type: news

Detecting early signs of cancer in the blood
Researchers developed a way to identify tumor cell DNA in blood samples from patients. The findings suggest a noninvasive way to detect cancer early and help guide treatment. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - August 29, 2017 Category: Consumer Health News Source Type: news

Probiotic prevents infant infections in rural India
A probiotic preparation reduced the risk of sepsis in a large study of newborns in rural India. The low-cost approach might help reduce sepsis in newborns around the world. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - August 28, 2017 Category: Consumer Health News Source Type: news

Brain cells that influence aging
Researchers discovered stem cells in the brain that influence how quickly mice age. The findings suggest new approaches to age-related diseases and lengthening lifespan. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - August 15, 2017 Category: Consumer Health News Source Type: news

Water changes mark Parkinson ’s disease progression
Scientists developed a new way to detect brain changes caused by Parkinson ’s disease. The technique may be useful for assessing the effects of potential treatments. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - August 15, 2017 Category: Consumer Health News Source Type: news

Risk factors for heart disease linked to dementia
A large, long-term study showed that certain heart disease risk factors in midlife —diabetes, elevated blood pressure, and smoking cigarettes—are associated with an increased risk for dementia. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - August 14, 2017 Category: Consumer Health News Source Type: news

Regenerating retinal cells in mice
Researchers coaxed cells in an injured mouse eye into regenerating neurons that integrate into the eye ’s circuitry. The findings may open the door to new treatments for eye damage and disease. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - August 8, 2017 Category: Consumer Health News Source Type: news