Allergic to penicillin? Probably not, study says
Most people who think they have a penicillin allergy really don ’t, and that mistaken belief could lead to them being prescribed less-effective, more expensive medications if they develop an infection, a new study found.  The underuse of penicillin could also contribute to the development of more drug-resistant bacteria, Pharmaceutical Journal reported. Res earchers at Massachusetts General Hospital found that although 10 percent of people in the United States believe they have a penicillin allergy,… (Source: bizjournals.com Health Care:Pharmaceuticals headlines)
Source: bizjournals.com Health Care:Pharmaceuticals headlines - August 13, 2018 Category: Pharmaceuticals Authors: Anne Stych Source Type: news

Deadly Respiratory Distress Mimic
Medic 534, staffed by a paramedic and EMT, is dispatched to a nursing home for a 78-year-old female in respiratory distress. On arrival, the crew finds the patient in a chair accompanied by two nurses and the administrator on call. The patient is in obvious distress showing fatigue and an increased work of breathing. She is alert to voice, but diaphoretic, lethargic, and unable to speak due to rapid, shallow breathing. A nurse is administering a nebulizer containing 3 mL of albuterol sulfate/ipratropium. A second nurse states that the patient has been in increasing distress for the last 45 minutes. The nurse also says that...
Source: JEMS Patient Care - July 17, 2018 Category: Emergency Medicine Authors: Brenton Faber, PhD, NRP Tags: Airway & Respiratory Patient Care Source Type: news

How Common is Recurrent Kawasaki Disease?
Patient Presentation A 3.5-year-old female came to clinic with a 2-day history fever up to 101°F. The evening before she had complained of a sore throat but had no rhinorrhea, cough or rash. She was drinking reasonably well and was urinating frequently. She had been to a birthday party where an older child had had strep throat. The past medical history was positive for Kawasaki Disease diagnosed at 17 months of age and treated with intravenous immunoglobulin (IVIG) on day 6 of fever. Her echocardiograms had been negative and she was being appropriately monitored by cardiology. The family history was positive for heart...
Source: PediatricEducation.org - July 16, 2018 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

Mayo Clinic Q and A: How could my penicillin allergy go away?
DEAR MAYO CLINIC: I always thought I was allergic to the antibiotic penicillin, but my doctor did an allergy test, and it turns out I?m not. How is that possible? ANSWER: An estimated 10 percent of people have been diagnosed as having an allergy to penicillin. Having a penicillin allergy on your health record is [...] (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - July 3, 2018 Category: Databases & Libraries Source Type: news

Risk of meticillin resistant Staphylococcus aureus and Clostridium difficile in patients with a documented penicillin allergy: population based matched cohort study
This research article covers a UK study (n=64,141 penicillin allergy [PA] and 237,258 matched comparators) noted documented penicillin allergy was linked to increased risk of MRSA (HR 1.69; 95% CI 1.51 to 1.90) and C difficile (1.26; 1.12 to 1.40) that was mediated by increased use of alternative (non- β lactam) antibiotics. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - June 29, 2018 Category: Consumer Health News Source Type: news

Penicillin Allergy Linked to MRSA, C. Difficile Risk
THURSDAY, June 28, 2018 -- There is a correlation for documented penicillin allergy with increased risk of methicillin-resistant Staphylococcus aureus (MRSA) and Clostridium difficile, which is mediated by increased use of β-lactam alternative... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - June 28, 2018 Category: Pharmaceuticals Source Type: news

People with penicillin allergies are far more likely to get superbugs, study reveals
People who have, or think they have, a penicillin allergy are more likely to get superbugs because they are given antibiotics which destroy good gut bacteria, a study by scientists in Boston says. (Source: the Mail online | Health)
Source: the Mail online | Health - June 28, 2018 Category: Consumer Health News Source Type: news

Testing for Penicillin Allergy May Cut 'Superbug' Infection Risk
Title: Testing for Penicillin Allergy May Cut 'Superbug' Infection RiskCategory: Health NewsCreated: 6/27/2018 12:00:00 AMLast Editorial Review: 6/28/2018 12:00:00 AM (Source: MedicineNet Allergies General)
Source: MedicineNet Allergies General - June 28, 2018 Category: Allergy & Immunology Source Type: news

Patients with penicillin allergy at increased risk of ‘superbug’ infections
Patients who have a record of a penicillin allergy are at an increased risk of developing the drug resistant infection MRSA and healthcare-associated infection C difficile, according to researchers. (Source: Nursing Times)
Source: Nursing Times - June 28, 2018 Category: Nursing Source Type: news

Possible penicillin allergy link to risk of ‘superbug’ infections
Risk of infections could be modified by prescribing changes Related items fromOnMedica Good evidence for sublingual immunotherapy Put case for adding leukaemia drug to Cancer Drugs Fund, NICE tells company NHS England will recruit 240 pharmacists for care homes Results from children ’s flu jab pilots ‘encouraging’ HIV therapy helps protect men from Hep B infection (Source: OnMedica Latest News)
Source: OnMedica Latest News - June 28, 2018 Category: UK Health Source Type: news

Penicillin Allergy Linked to MRSA, C difficile Infections Penicillin Allergy Linked to MRSA, C difficile Infections
Patients with documented penicillin allergy have a greater risk of developing new methicillin-resistant Staphylococcus aureus and Clostridium difficile infections, a study has found.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - June 27, 2018 Category: Consumer Health News Tags: Infectious Diseases News Source Type: news

Testing for Penicillin Allergy May Cut'Superbug' Infection Risk
WEDNESDAY, June 27, 2018 -- People believed to have a penicillin allergy are often prescribed much stronger antibiotics that can raise their risk for dangerous infections, a new study suggests. But testing folks to make sure they really are allergic... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - June 27, 2018 Category: General Medicine Source Type: news

Patients believed allergic to penicillin have increased risks of MRSA and C. difficile
(Massachusetts General Hospital) Analysis of outpatient records of large number of British patients reveals that those believed to be allergic to penicillin have significantly increased risks of contracting the dangerous infections MRSA and C. difficile. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - June 27, 2018 Category: Infectious Diseases Source Type: news

Malaria-Free Paraguay; Don't Neglect Nipah Virus; Global Penicillin Shortage?
(MedPage Today) -- News and commentary from the world of infectious diseases (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - June 13, 2018 Category: Primary Care Source Type: news

Shortage of important form of penicillin affecting 39 countries, including India: AMF
In Brazil, the shortage of penicillin coincided with a syphilis outbreak that, as a result, could not be brought under control. Between 2012 and 2015. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - June 1, 2018 Category: Pharmaceuticals Source Type: news

Penicillin G Benzathine (Bicillin L-A) Injection (Updated - Resolved)
Drug Shortage (Source: FDA Drug Shortages)
Source: FDA Drug Shortages - May 8, 2018 Category: Drugs & Pharmacology Source Type: news

Delabelling penicillin allergy after testing is safe and cost saving
(Source: PharmacoEconomics and Outcomes News)
Source: PharmacoEconomics and Outcomes News - May 1, 2018 Category: Drugs & Pharmacology Source Type: news

How Bacteria Eat Penicillin
Scientists work out the specific genes and biochemical steps required for digesting the very drugs designed to kill microbes. (Source: The Scientist)
Source: The Scientist - April 30, 2018 Category: Science Tags: Daily News,The Scientist Source Type: news

Gustav Born obituary
Prominent pharmacologist whose pioneering work on how the body stops bleeding improved the detection of thrombosisIn 1945, Gustav Born, a young and recently qualified doctor serving with the Royal Army Medical Corps, was among the first allied staff to witness the medical aftermath of the atomic bomb blast in Hiroshima. Among the horrific injuries he encountered, one struck him particularly forcibly: the tendency of the survivors to suffer from severe bleeding disorders. This, he surmised, was attributable to a lack of blood platelets caused by radiation damage. It was evidently a decisive experience, for it set the course...
Source: Guardian Unlimited Science - April 26, 2018 Category: Science Authors: Rod Flower Tags: Medical research People in science Medicine University of Oxford King's College London University of Cambridge Source Type: news

Been told you have a penicillin allergy? There is chance it's not real
A new study shows the benefits of removing penicillin allergy labels for kids. (Source: ABC News: Health)
Source: ABC News: Health - April 20, 2018 Category: Consumer Health News Tags: GMA Source Type: news

WATCH: Are you actually allergic to penicillin?
Dr. Jennifer Ashton discusses what to know about a new study that suggests a majority of children who have a penicillin allergy can take penicillin-based antibiotics without a problem. (Source: ABC News: Health)
Source: ABC News: Health - April 20, 2018 Category: Consumer Health News Tags: GMA Source Type: news

Delabeling for Penicllin Allergy Found Safe in Children Delabeling for Penicllin Allergy Found Safe in Children
Children with low-risk penicillin allergy symptoms who tested negative for penicillin allergy tolerated penicillin without serious adverse or allergic reactions during the following year, a study found.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - April 20, 2018 Category: Consumer Health News Tags: Pediatrics News Source Type: news

Delabeling for Penicillin Allergy Found Safe in Children Delabeling for Penicillin Allergy Found Safe in Children
Children with low-risk penicillin allergy symptoms who tested negative for penicillin allergy tolerated penicillin without serious adverse or allergic reactions during the following year, a study found.Medscape Medical News (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - April 20, 2018 Category: Consumer Health News Tags: Pediatrics News Source Type: news

Digital Penicillin Production
For thousands of years, micro-organisms have been used to facilitate chemical reactions - in beer brewing, for example. However, biochemical processes are incredibly complex, with a multitude of reactions taking place simultaneously and influencing one another. There are countless parameters that play a role, not all of which can be directly measured. (Source: eHealth News EU)
Source: eHealth News EU - April 10, 2018 Category: Information Technology Tags: Featured Research Research and Development Source Type: news

Orchid gets three final bids at par with liquidation value
The company had to sell assets to rein in debt. In 2012, it sold its penicillin business to US drug maker Hospira for $200 million. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - March 19, 2018 Category: Pharmaceuticals Source Type: news

AAAAI: Penicillin Allergy Label Linked to MRSA, C. difficile
(MedPage Today) -- Increase attributable to use of alternative antibiotics (Source: MedPage Today Infectious Disease)
Source: MedPage Today Infectious Disease - March 5, 2018 Category: Infectious Diseases Source Type: news

EMedHome's Clinical Pearl: Does This Patient Really Have a Penicillin Allergy?
No abstract available (Source: Emergency Medicine News)
Source: Emergency Medicine News - March 1, 2018 Category: Emergency Medicine Tags: EMedHome's Clinical Pearl Source Type: news

An enzyme's evolution from changing electric fields and resisting antibiotics
(Biophysical Society) Bacteria can produce enzymes that make them resistant to antibiotics; one example is the TEM beta-lactamase enzyme, which enables bacteria to develop a resistance to beta-lactam antibiotics, such as penicillin and cephalosporins. Researchers at Stanford University are studying this area -- how an enzyme changes and becomes antibiotic-resistant -- and will present their work during the Biophysical Society's 62nd Meeting, held Feb. 17-21, 2018. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 19, 2018 Category: International Medicine & Public Health Source Type: news

High levels of antibiotic resistance found worldwide, new data show
BANGKOK 29 January 2018 – The World Health Organization’s first release of surveillance data on antibiotic resistance reveals high levels of resistance to a number of serious bacterial infections in both high- and low-income countries. WHO’s new Global Antimicrobial Surveillance System (known as GLASS) reveals widespread occurrence of antibiotic resistance among 500 000 people with suspected bacterial infections across 22 countries.  The most commonly reported resistant bacteria were Escherichia coli, Klebsiella pneumoniae, Staphylococcus aureus, and Streptococcus pneumoniae, followed by Salmo...
Source: WHO EMRO News - January 29, 2018 Category: Middle East Health Source Type: news

Weekly Postings
Happy New Year from NNLM MAR! We are excited to share information with you about our upcoming projects, classes, and news from around the Middle Atlantic Region. See something of interest? Please share our postings with colleagues in your institutions! Spotlight Welcome, Veronica Leigh Milliner! On January 2, Veronica Leigh Milliner, MLIS, joined NNLM MAR in the newly created position of All of Us Community Engagement Coordinator. Veronica will work within our region and in collaboration with other regional and national All of Us Program partners and the National Network of Libraries of Medicine to develop, pilot, model, a...
Source: NN/LM Middle Atlantic Region Blog - January 5, 2018 Category: Databases & Libraries Authors: Hannah Sinemus Tags: Weekly Postings Source Type: news

U.N. warns: Antibiotic use in farming is spreading via waterways, driving the superbug resistance crisis, putting millions of lives at risk
(Natural News) When Alexander Fleming discovered the first antibiotic – penicillin – in 1928, the world of medicine was changed forever. His discovery led to the development of medicines that could treat cuts, abrasions and bacterial infections, saving millions, if not billions, of lives. Sadly, however, misuse and overuse of antibiotics have fostered the development... (Source: NaturalNews.com)
Source: NaturalNews.com - January 1, 2018 Category: Consumer Health News Source Type: news

From Snake Oil to Penicillin: Evaluating Consumer Health on the Internet
January 8-29, 2018. Free, asynchronous course to evaluate health information on the internet. (Source: HSR Information Central)
Source: HSR Information Central - December 28, 2017 Category: International Medicine & Public Health Source Type: news

Drug Allergies: Time to Re-Test?
(MedPage Today) -- Penicillin allergy may be more belief than fact (Source: MedPage Today Allergy)
Source: MedPage Today Allergy - December 20, 2017 Category: Allergy & Immunology Source Type: news

How Does Pediatric Sj ö gren Syndrome Present?
Discussion Sjögren Syndrome (SS) is named for Swedish ophthalmologist Henrik Sjögren who published a case series in 1933 describing patients with dry eyes and arthritis. SS is a “chronic autoimmune inflammatory exocrinopathy” that is characterized by lymphocytic infiltration of the lacrimal and salivary glands and has various degrees of systematic involvement. Keratoconjunctivitis sicca and xerostomia are the main clinical symptoms. Sicca is a Latin word meaning dry. Dryness of the eyes and mouth without evidence of autoimmune disease is called Sicca syndrome or Sicca complex. SS can be primary or se...
Source: PediatricEducation.org - December 11, 2017 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

Resistance to Antibiotics: The Good, the Bad and the Ugly
Antimicrobial drugs play a critical role in the treatment of diseases, their use is essential to protect both human and animal health. However, antimicrobials are often misused for treatment and prevention of diseases in livestock sector, aquaculture as well as crop production. Credit: FAOBy Baher KamalROME, Dec 6 2017 (IPS)The growing resistance to antibiotics and other antimicrobials due to their overuse and misuse both in humans and animals has become an alarming global threat to public health, food safety and security, causing the deaths of 700,000 people each year. This is a fact. The good news is that now more and mo...
Source: IPS Inter Press Service - Health - December 6, 2017 Category: International Medicine & Public Health Authors: Baher Kamal Tags: Editors' Choice Environment Featured Food & Agriculture Global Headlines Health Humanitarian Emergencies IPS UN: Inside the Glasshouse Poverty & SDGs Projects Regional Categories TerraViva United Nations Improving the lives of ru Source Type: news

Resistance to Popular Antibiotic Began Years Ago
Ampicillin, a broad-spectrum penicillin, is widely used to treat many bacterial infections, including bladder and ear infections, pneumonia and gonorrhea. (Source: WebMD Health)
Source: WebMD Health - November 30, 2017 Category: Consumer Health News Source Type: news

Resistance to Popular Antibiotic Likely Began Years Before Human Use
THURSDAY, Nov. 30, 2017 -- Bacterial resistance to the antibiotic ampicillin may have begun years before doctors started prescribing it in the early 1960s, a new study suggests. Ampicillin, a broad-spectrum penicillin, is widely used to treat many... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - November 30, 2017 Category: General Medicine Source Type: news

Ampicillin resistance 'started in agriculture'
Researchers say overuse of penicillin on farms in the 1950s triggered human resistance Related items fromOnMedica Massive fall in animal antibiotic use Interventions cut inappropriate antibiotic prescribing US use of broad-spectrum antibiotics shows worrying increase Study quantifies human consequences of increased antibiotic resistance United global effort needed to fight antimicrobial resistance (Source: OnMedica Latest News)
Source: OnMedica Latest News - November 30, 2017 Category: UK Health Source Type: news

Antibiotic resistance: An unexpected chronology
(Institut Pasteur) Researchers from Institut Pasteur have shed light on the rise of ampicillin resistance back in the 60s. Through the sampling of Salmonella strains, they proved that antibiotic resistance can be traced back prior to the release of ampicillin on the UK market. Their discovery suggests that penicillin fed to livestock in the 1950s may have encouraged antibiotic-resistant bacteria to evolve and spread. These results will be published in The Lancet Infectious Diseases on Wednesday, Nov. 29. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - November 29, 2017 Category: Infectious Diseases Source Type: news

Penicillin G Procaine (Penicilling Procaine Injection) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - November 17, 2017 Category: Drugs & Pharmacology Source Type: news

Penicillin G Procaine (Penicilling Procaine Injection) - new on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - November 16, 2017 Category: Drugs & Pharmacology Source Type: news

When'Allergic to Penicillin' Isn't True in Children When'Allergic to Penicillin' Isn't True in Children
A study seeks to determine how many low-risk children thought to have penicillin allergy are truly penicillin allergic.Medscape Pediatrics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - November 1, 2017 Category: Consumer Health News Tags: Pediatrics Viewpoint Source Type: news

Patients Who Claim Penicillin Allergy Often Aren't Allergic
(MedPage Today) -- Penicillin skin test feasible in'real-world'office setting, researchers say (Source: MedPage Today Allergy)
Source: MedPage Today Allergy - October 31, 2017 Category: Allergy & Immunology Source Type: news

Bacterial toxins made in the gut
(Wiley) You get an infection, you are given penicillin--and then you could get hemorrhagic diarrhea. This rare but extremely unpleasant side reaction can be related to the enterotoxin tilivalline produced by a regular intestinal bacterium. Austrian scientists have now scrutinized the toxin's biosynthetic pathway and presented the results in the journal Angewandte Chemie. Their findings give important insights in the pathobiology of antibiotic side reactions and unveil the multifunctionality of bacterial toxins. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - October 25, 2017 Category: Biology Source Type: news

Reported penicillin allergy appears to increase the risk of surgical site infections
Data from a study published online in the journal Clinical Infectious Diseases suggest that patients with a reported penicillin allergy may have a 50 percent increased chance of contracting a surgical site infection (SSI).  (Source: Orthogate - Latest News)
Source: Orthogate - Latest News - October 15, 2017 Category: Orthopaedics Tags: Featured Editors Choice News Source Type: news

Penicillin Allergy Linked With Higher Risk of Surgical-site Infection Penicillin Allergy Linked With Higher Risk of Surgical-site Infection
Patients who report penicillin allergy face an increased risk of surgical-site infection (SSI), according to a retrospective study.Reuters Health Information (Source: Medscape General Surgery Headlines)
Source: Medscape General Surgery Headlines - October 11, 2017 Category: Surgery Tags: General Surgery News Source Type: news

Patients with reported penicillin allergy at ‘higher SSI risk’
Patients who report having a prior penicillin allergy have been found to have a 50% increased risk of developing a surgical site infection (SSI), according to US researchers. (Source: Nursing Times)
Source: Nursing Times - October 10, 2017 Category: Nursing Source Type: news

Penicillin Misconceptions May Raise Post-Op Infection Risk
Title: Penicillin Misconceptions May Raise Post-Op Infection RiskCategory: Health NewsCreated: 10/9/2017 12:00:00 AMLast Editorial Review: 10/10/2017 12:00:00 AM (Source: MedicineNet Allergies General)
Source: MedicineNet Allergies General - October 10, 2017 Category: Allergy & Immunology Source Type: news

Penicillin allergy may increase risk of surgical site infection
A recent study by Massachusetts General Hospital researchers found that a penicillin allergy may increase the risk of surgical site infections. (Source: Health News - UPI.com)
Source: Health News - UPI.com - October 9, 2017 Category: Consumer Health News Source Type: news