This Biotech Startup Just Raised $47 Million To Make Drugs From Fungi
In order to find the next penicillin, Menlo Park-based startup Hexagon Bio uses an AI platform to sequence the genomes of fungi. (Source: Forbes.com Healthcare News)
Source: Forbes.com Healthcare News - September 15, 2020 Category: Pharmaceuticals Authors: Leah Rosenbaum, Forbes Staff Tags: Innovation /innovation Healthcare /healthcare Science /science Editors' Pick editors-pick Source Type: news

Looking Back to Look Forward: What Does the Next Normal Look Like?
This article was originally published by Work in Progress The post Looking Back to Look Forward: What Does the Next Normal Look Like? appeared first on Inter Press Service. Excerpt: Gary Rynhart, Specialist, Employers’ Activities, DWT/CO-Pretoria, International Labour Organization (ILO) The post Looking Back to Look Forward: What Does the Next Normal Look Like? appeared first on Inter Press Service. (Source: IPS Inter Press Service - Health)
Source: IPS Inter Press Service - Health - August 28, 2020 Category: International Medicine & Public Health Authors: Gary Rynhart Tags: Economy & Trade Global Global Governance Headlines Health Labour Population TerraViva United Nations Source Type: news

Are antivitamins the new antibiotics?
(University of G ö ttingen) Antibiotics are among the most important discoveries of modern medicine and have saved millions of lives since the discovery of penicillin almost 100 years ago. However, bacteria can develop resistance to antibiotics which then leaves doctors struggling to find effective treatments. Researchers at the University of G ö ttingen and the MPI for Biophysical Chemistry G ö ttingen have now described a promising new approach involving " antivitamins " to develop new classes of antibiotics. Results were published in Nature Chemical Biology. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 24, 2020 Category: International Medicine & Public Health Source Type: news

Drug vignettes: Remdesivir, CEBM
The results of the compassionate-use programme for remdesivir suggest, but do not prove, that the benefits of remdesivir may outweigh the harms it might cause. It is reminiscent of the early case reports of the success of penicillin in infective endocarditis. However, the mortality rate from COVID-19 is, by the standards of acute infective endocarditis, relatively low, and so an open, uncontrolled trial will never be able to define the benefits or harms. In human subjects, the results of randomized, controlled trials have yet to show that remdesivir affects mortality in the short-term, although one study did show that pat...
Source: Current Awareness Service for Health (CASH) - August 10, 2020 Category: Consumer Health News Source Type: news

Malvern antibiotics developer Venatorx lands NIH contract worth as much as $44M
A Chester County biopharmaceutical company focused on antibiotics could receive as much as $44.2 million under a research and development contract it received from a division of the National Institute of Health. The contract was awarded to Venatorx Pharmaceuticals by the National Institute of Allergy and Infectious Diseases (NIAID). Malvern-based Venatorx will use the funds to advance a novel series of penicillin-binding protein inhibitors it is developing to target multi-drug resistant acinetobacter… (Source: bizjournals.com Health Care:Biotechnology headlines)
Source: bizjournals.com Health Care:Biotechnology headlines - July 27, 2020 Category: Biotechnology Authors: John George Source Type: news

Many Cases of'Penicillin Allergy' Might Be Mistaken
Title: Many Cases of'Penicillin Allergy'Might Be MistakenCategory: Health NewsCreated: 7/8/2020 12:00:00 AMLast Editorial Review: 7/9/2020 12:00:00 AM (Source: MedicineNet Allergies General)
Source: MedicineNet Allergies General - July 9, 2020 Category: Allergy & Immunology Source Type: news

Many Cases of'Penicillin Allergy' Might Be Mistaken
WEDNESDAY, July 8, 2020 -- Penicillin allergy is often unconfirmed in hospital patients, meaning many unnecessarily receive other antibiotics that may be less effective and even harmful, a new study finds. The researchers analyzed records of nearly... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - July 8, 2020 Category: General Medicine Source Type: news

Many antibiotic substitutions for self-reported penicillin allergies likely unnecessary
(Massachusetts General Hospital) Diagnostic testings or evaluations show that the vast majority of patient-reported allergies to penicillin could be disproven. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - June 30, 2020 Category: Infectious Diseases Source Type: news

Penicillin allergy increases risk for use of less-effective antibiotics, study finds
People allergic to penicillin are nearly twice as likely to receive a less-effective antibiotic with more side effects when hospitalized than those who are not allergic to the drug. (Source: Health News - UPI.com)
Source: Health News - UPI.com - June 29, 2020 Category: Consumer Health News Source Type: news

CDC Issues Health Advisory on Meningococcal Disease
The CDC on June 18 issued a health advisory notifying physicians about recent case reports of patients with meningococcal disease that is resistant to both penicillin and ciprofloxacin. (Source: AAFP News)
Source: AAFP News - June 22, 2020 Category: Primary Care Source Type: news

Drug-Resistant Meningitis Found in Several US Patients Drug-Resistant Meningitis Found in Several US Patients
The CDC has identified 11 meningococcal isolates with evidence of resistance to penicillin and ciprofloxacin, according to a Health Alert Network health advisory.Medscape Medical News (Source: Medscape Emergency Medicine Headlines)
Source: Medscape Emergency Medicine Headlines - June 19, 2020 Category: Emergency Medicine Tags: Infectious Diseases News Source Type: news

$1.77M award gives Temple researchers chance to investigate therapy for cocaine addiction
(Temple University Health System) Researchers at the Lewis Katz School of Medicine at Temple University have received a new $1.77M grant from the National Institute on Drug Abuse that will allow them to explore whether a drug called clavulanic acid can help patients recover from cocaine use disorder. Clavulanic acid is part of an existing therapy known as Augmentin. Augmentin combines clavulanic acid with the penicillin-related antibiotic amoxicillin and is used for the treatment of bacterial infections. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - June 15, 2020 Category: International Medicine & Public Health Source Type: news

Non-Penicillin Beta-Lactam Drugs: A CGMP Framework for Preventing Cross-Contamination
Pharmaceutical Quality/Manufacturing Standards (CGMP) (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - May 14, 2020 Category: Drugs & Pharmacology Authors: FDA Source Type: news

Study shows ICU patients with low-risk penicillin allergies can be tested and treated
(Vanderbilt University Medical Center) Many patients previously diagnosed with a penicillin allergy can have their allergy label removed after testing and safely undergo treatment with penicillin medications, according to a study published in American Journal of Respiratory and Critical Care Medicine. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - April 2, 2020 Category: International Medicine & Public Health Source Type: news

Hospitals Got $100 Billion in the Stimulus Package. But A Lot of That Could Go Toward Administrative Costs
Hospitals have spent the past few weeks racing to respond to the growing COVID-19 crisis, supplementing shortages of equipment, calling back retired personnel, and transforming entire hospital wings to care for infected patients. So when Congress included $100 billion in the stimulus package passed last week to help hospitals and other health care providers address the pandemic, it was seen as much-needed assistance. But that’s not the whole story, health care experts say. Due to the patchwork nature of the U.S. health care system, a huge chunk of those emergency funds likely won’t go to lifesaving care or equi...
Source: TIME: Health - April 1, 2020 Category: Consumer Health News Authors: Abigail Abrams Tags: Uncategorized COVID-19 Source Type: news

The Coronavirus Pandemic Is Creating a Drug Supply Crisis Just When We Most Need Medicine
As the world scrambles for a magic pharmaceutical bullet to stop the coronavirus, drugs perceived as cures – despite reed-thin evidence — have vanished from pharmacy shelves. Just last Friday, after President Trump touted the still unproven remedy of a malaria drug, hydroxychloroquine, the Food and Drug Administration lifted a restriction it had imposed on a Indian drug manufacturer with a record of manipulating its quality data, to allow it to make the active ingredient now suddenly in hot demand. With the United States long dependent on foreign drug manufacturers for low-cost medicine and key drug ingredients...
Source: TIME: Health - March 26, 2020 Category: Consumer Health News Authors: Katherine Eban Tags: Uncategorized COVID-19 Source Type: news

Simple Decision Rule Helps Identify People at Low-Risk for Penicillin Allergy Simple Decision Rule Helps Identify People at Low-Risk for Penicillin Allergy
A simple clinical decision rule for penicillin allergy can help doctors and antimicrobial-stewardship programs identify people at low-risk of penicillin allergy at the point of care, report doctors from Australia who developed and validated the PEN-FAST rule.Reuters Health Information (Source: Medscape Allergy Headlines)
Source: Medscape Allergy Headlines - March 19, 2020 Category: Allergy & Immunology Tags: Allergy & Clinical Immunology News Source Type: news

Associations between macrolide antibiotics prescribing during pregnancy and adverse child outcomes in the UK: population based cohort study
Prescribing macrolide antibiotics during the first trimester of pregnancy was associated with an increased risk of any major malformation and specifically cardiovascular malformations compared with penicillin antibiotics. Macrolide prescribing in any trimester was associated with an increased risk of genital malformations. These findings show that macrolides should be used with caution during pregnancy and if feasible alternative antibiotics should be prescribed until further research is available. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - February 26, 2020 Category: Consumer Health News Source Type: news

Common Antibiotics Linked To Increased Risk Of Birth Defects, Study Says
(CNN) — Taking some common antibiotics during the first trimester of pregnancy was linked with higher risk of birth defects, according to a new study. The study, published Wednesday in the medical journal BMJ, found an increased risk of birth defects in the children of women who were prescribed macrolides during the first three months of pregnancy compared to mothers who were prescribed penicillin. Macrolide antibiotics include erythromycin, clarithromycin and azithromycin, and they are used to treat infections, such as pneumonia, bronchitis and urinary, skin and sexually transmitted diseases. They are often prescrib...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - February 20, 2020 Category: Consumer Health News Authors: Health – CBS Boston Tags: Health News CNN Source Type: news

Babies 'face birth defect risk if their mothers take penicillin alternatives during pregnancy'
Research by University College London said that the risk of heart, brain or genital defects was 55 per cent higher among babies whose mothers took macrolide antibiotics during their pregnancy. (Source: the Mail online | Health)
Source: the Mail online | Health - February 20, 2020 Category: Consumer Health News Source Type: news

EMERGENCY MEDICINE skills: Creating your own penicillin at home
(Natural News) The discovery of penicillin was considered a landmark that changed the face of modern medicine. Penicillin refers to a group of powerful antibacterial drugs that target a wide variety of bacterial infections. While the overuse of antibiotics has been a growing problem in recent years, there is no denying the fact that there... (Source: NaturalNews.com)
Source: NaturalNews.com - February 13, 2020 Category: Consumer Health News Source Type: news

Could Strep Throat Become Untreatable?
A new study warns that strains of bacteria that cause strep throat and "flesh-eating disease" appear close to becoming resistant to penicillin and other antibiotics known as beta-lactams. (Source: WebMD Health)
Source: WebMD Health - January 30, 2020 Category: Consumer Health News Source Type: news

Could Strep Throat Become Untreatable?
THURSDAY, Jan. 30, 2020 -- When a child has strep throat, an antibiotic like penicillin usually has them back at school 24 hours later. But a new study warns that strains of bacteria that cause strep throat and " flesh-eating disease " appear close... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - January 30, 2020 Category: General Medicine Source Type: news

Discovery reveals antibiotic-resistant strep throat may be too close for comfort
(Houston Methodist) Infectious disease scientists identified strains of group A streptococcus that are less susceptible to commonly used antibiotics, a sign that the germ causing strep throat and flesh-eating disease may be moving closer to resistance to penicillin and other related antibiotics known as beta-lactams. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - January 29, 2020 Category: Infectious Diseases Source Type: news

Fetal Bovine Serum-More Data
Primary and Stem Cell CultureThis just came across our radar." SUPPLEMENTARY MATERIAL An eye opener in stroke: Mitochondrial dysfunction and stem cell repair in MCAO induced retinal ischemia "We are always delighted when researchers supplement their cell culture media with ourFetal Bovine Serum (FBS).RPE Cells and MSC Culture Retinal pigmented epithelium (RPE, CRL-4000; ATCC) cells were cultured in Dulbecco ’s Modified Eagle Media/F-12 (DMEM/F-12, 11320033; Gibco) containing 10% fetal bovine serum (FBS; FBS001; Neuromics) and 0.01 mg/ml hygromycin B (10687010; Gibco) in incubator (37 °C humidified, with...
Source: Neuromics - January 17, 2020 Category: Neuroscience Tags: adult stem cells FBS Fetal Bovine Serum Human Mesenchymal Stem Cells MSCs Retinal Pigment Epithelial Cells RPES Source Type: news

The top 10 most important survival and prepping stories of 2019
(Natural News) With our world seemingly on the brink of some major calamities, it’s probably a good idea to get prepared. Here are 10 of the best ideas from this past year’s news lineup: How to make your own penicillin… just in case One of the most significant discoveries in modern medicine, penicillin has saved... (Source: NaturalNews.com)
Source: NaturalNews.com - December 16, 2019 Category: Consumer Health News Source Type: news

Minestrone Meets Malaria, And Wins
While chicken soup has often been considered as effective as penicillin to treat many illnesses, or at least bad colds, a new study looks at different kinds of soups (yes, soups) to battle a more serious infection —malaria. (Source: Forbes.com Healthcare News)
Source: Forbes.com Healthcare News - December 9, 2019 Category: Pharmaceuticals Authors: Nina Shapiro, Contributor Source Type: news

Penicillin Allergy Less Common Than Thought: Study
Title: Penicillin Allergy Less Common Than Thought: StudyCategory: Health NewsCreated: 11/25/2019 12:00:00 AMLast Editorial Review: 11/26/2019 12:00:00 AM (Source: MedicineNet Allergies General)
Source: MedicineNet Allergies General - November 26, 2019 Category: Allergy & Immunology Source Type: news

Penicillin Allergy Less Common Than Thought: Study
MONDAY, Nov. 25, 2019 -- Millions of Americans think they're allergic to penicillin, but they're not, a new study reveals. This erroneous belief adds millions of dollars to health care costs and results in unnecessary side effects from more... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - November 25, 2019 Category: General Medicine Source Type: news

French doctor still treating patients at 98
When French doctor Christian Chenay saw his first patients in 1951, penicillin was state of the art. (Source: Reuters: Health)
Source: Reuters: Health - November 22, 2019 Category: Consumer Health News Tags: healthNews Source Type: news

Medical News Today: 9 in 10 people who think they are allergic to penicillin may not be
Three new studies shed fresh light on penicillin allergy, pointing out that many people who have been allergic in their childhood may no longer be so. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - November 18, 2019 Category: Consumer Health News Tags: Allergy Source Type: news

Will you pass the penicillin allergy quiz?
While 10% of Americans report being allergic to penicillin, 9 of 10 have actually outgrown it or never had it in the first place, according to new studies presented at the American College of Allergy, Asthma and Immunology Annual Scientific Meeting. Over-reporting can lead to a number of problems, including increased antibiotic resistance. Dr. Nipunie Rajapakse, [...] (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - November 18, 2019 Category: Databases & Libraries Source Type: news

Skin Tests Can Overestimate Penicillin Allergy Skin Tests Can Overestimate Penicillin Allergy
Women are more likely than men to have a positive skin prick response for penicillin allergy, new research shows, but only an oral test tells the truth about penicillin allergy, another expert argues.Medscape Medical News (Source: Medscape Allergy Headlines)
Source: Medscape Allergy Headlines - November 15, 2019 Category: Allergy & Immunology Tags: Allergy & Clinical Immunology News Source Type: news

Woman, 46, with severe allergy to penicillin goes into anaphylactic shock after unprotected sex
The 46-year-old, from Baltimore, Maryland, broke out in blotchy red patches, began sweating profusely and became dizzy within an hour after intercourse. She was taken to A&E and hooked up to an IV. (Source: the Mail online | Health)
Source: the Mail online | Health - November 7, 2019 Category: Consumer Health News Source Type: news

Most Americans Who Think They ’ re Allergic to Penicillin Aren ’ t, Study Finds
BOSTON (CBS)- Think you’re allergic to penicillin?  Chances are…you’re not.  In fact, more than 30 million people in the United States wrongly believe they’re allergic to penicillin. Many people report that they’re allergic to penicillin, or amoxicillin, or one of the other penicillin’s, often saying they’re mom told them they had some type of reaction when they were little. So many doctors turn to other types of antibiotics to treat common ailments like strep throat or ear infections, which may be more expensive, have more side effects, and could contribute to greater a...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - October 30, 2019 Category: Consumer Health News Authors: Health – CBS Boston Tags: Boston News Health Healthwatch Syndicated CBSN Boston Syndicated Local Allergies Dr. Mallika Marshall Health Watch penicillin penicillin allergy Source Type: news

He ’s the First African American to Receive a Face Transplant. His Story Could Change Health Care
Robert Chelsea turned down the first face he was offered. It was a fine face, one that could have taken him off the transplant waiting list after just a couple months. But Chelsea—severely disfigured after a catastrophic car accident five years earlier—was in no hurry. He’d gotten used to tilting his head back so food and water wouldn’t fall out of his nearly lipless mouth. He knew how to respond compassionately to children who stared in shock and fear. The face, offered in May 2018, had belonged to a man with skin that was much fairer than what remained of Chelsea’s—so light that Chelse...
Source: TIME: Health - October 24, 2019 Category: Consumer Health News Authors: Jamie Ducharme Tags: Uncategorized Healthcare Source Type: news

Penicillin V four times daily for five days versus three times daily for 10 days in patients with pharyngotonsillitis caused by group A streptococci: randomised controlled, open label, non-inferiority study
this research article concludes that Penicillin V four times daily for five days was non-inferior in clinical outcome to penicillin V three times daily for 10 days in patients with pharyngotonsillitis caused by group A streptococci. The number of relapses and complications did not differ between the two intervention groups. Five day treatment with penicillin V four times daily might be an alternative to the currently recommended 10 day regimen. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - October 16, 2019 Category: Consumer Health News Source Type: news

Bicillin C-R 900/300 (Penicillin G Benzathine and Penicillin G Procaine Injection) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - September 6, 2019 Category: Drugs & Pharmacology Source Type: news

NAM President Delivers Lecture at Nobel Conference
National Academy of Medicine President Victor Dzau delivered a plenary lecture at the Nobel conference, which was held at the Nobel Forum in Stockholm, Sweden, about major medical breakthroughs and lifesaving therapies, such as penicillin and statins, that are the consequences of basic discovery research on nature. Read More (Source: News from the National Academies)
Source: News from the National Academies - September 5, 2019 Category: Science Source Type: news

Seaweed forests hold key to overcoming antibiotic resistance, says study
(Natural News) One of the greatest challenges facing modern medicine today is antibiotic resistance. Almost a century since Penicillin was first discovered in strains of mold, medical science has isolated thousands of defensive, antibiotic compounds from microbes. These bio-active microbial metabolites have been mass produced as antibiotics to help humans fight infections. Because the human... (Source: NaturalNews.com)
Source: NaturalNews.com - September 3, 2019 Category: Consumer Health News Source Type: news

Some antibiotics linked to a higher risk of colon cancer,
Scientists at Johns Hopkins University found that people who developed bowel cancer were more likely to have taken penicillin. But tetracyclines may have protective effects for rectal cancer. (Source: the Mail online | Health)
Source: the Mail online | Health - August 21, 2019 Category: Consumer Health News Source Type: news

Half of bacteria on London's door handles 'are antibiotic-resistant'
Researchers led by the University of East London swabbed 600 frequently-touched surfaces in the city and found many were resistant to widely-used drugs including penicillin. (Source: the Mail online | Health)
Source: the Mail online | Health - August 1, 2019 Category: Consumer Health News Source Type: news

penicillin V
Title: penicillin VCategory: MedicationsCreated: 12/31/1997 12:00:00 AMLast Editorial Review: 7/18/2019 12:00:00 AM (Source: MedicineNet Medications General)
Source: MedicineNet Medications General - July 18, 2019 Category: Drugs & Pharmacology Source Type: news

Superbug MRSA susceptible to existing antibiotics
Methicillin-resistantStaphylococcus aureus (MRSA) has become a serious problem, forcing doctors to turn to antibiotics other than penicillin or penicillin derivatives, or to different drug cocktails, which are often less effective in treating hospital and community based infections. (Source: Medical Research Council General News)
Source: Medical Research Council General News - June 25, 2019 Category: Research Source Type: news

Focus group study exploring the issues and the solutions to incorrect penicillin allergy-labelled patients: an antibiotic stewardship patient safety initiative
Focus group (17 hospital doctors, nurses& pharmacists) found that identifying& delabelling incorrect penicillin allergy was a complex task and not a priority, but that they felt confident removing erroneous allergy records if the patient was able to describe the reaction. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - June 13, 2019 Category: Consumer Health News Source Type: news

Clinical features and antimicrobial susceptibility profiles of culture-proven neonatal sepsis in a tertiary children's hospital, 2013 to 2017.
Neonatal sepsis (NS) remains a major cause of morbidity and mortality in neonates, but data on the etiology and antibiotic susceptibility patterns of pathogens are limited. The aim of this study was to analyze the clinical characteristics, risk factors, and the antibiotic susceptibility patterns of pathogenic microbes associated with NS at a tertiary children's hospital in Shanghai, China. Most isolates of Gram-positive bacteria were sensitive to vancomycin, linezolid, minocycline and tigecycline, of which more than 90% were resistant to penicillin. Most isolates of Gram-negative bacteria were sensitive to amikacin and imi...
Source: Current Awareness Service for Health (CASH) - May 29, 2019 Category: Consumer Health News Source Type: news

Medical News Today: Augmentin (Amoxicillin/clavulanate potassium)
Augmentin (amoxicillin/clavulanate potassium) is a prescription medication that ’s used to treat infections caused by bacteria. It belongs to a class of drugs called penicillin antibiotics. Augmentin comes as an oral tablet and an oral liquid suspension. Learn about side effects, warnings, dosage, and more. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - May 17, 2019 Category: Consumer Health News Tags: Infectious Diseases / Bacteria / Viruses Source Type: news

Bicillin C-R Tubex (Penicillin G Benzathine and Penicillin G Procaine Injection) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - May 13, 2019 Category: Drugs & Pharmacology Source Type: news

Bicillin L-A Injectable in Tubex (Penicillin G Benzathine Injectable in Tubex) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - May 13, 2019 Category: Drugs & Pharmacology Source Type: news