VBCs: Are They Working?
As an observer, it can be difficult to find out what ’s happening with value-based contracts (VBCs). The fanfare that accompanies the announcement of a deal invariably gives way to a long period of silence, a good sign if you subscribe to the mantra that no news is good news, but if you don’t, there is cause for concern.The smattering of reports on the topic suggest that green shoots are emerging. A recent survey of 120 payers conducted by the ORC International and commissioned by Change Healthcare, found that payers reported an average saving in medical costs of 5.6% from VBC strategies with an accompanying 77...
Source: EyeForPharma - December 12, 2018 Category: Pharmaceuticals Authors: Adam Chapman Source Type: news

Medical News Today: What to know about marijuana and multiple sclerosis
Marijuana has many potential uses, which includes the treatment of specific symptoms of multiple sclerosis (MS). Learn more about the possible benefits of marijuana for people with MS here. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - December 11, 2018 Category: Consumer Health News Tags: Multiple Sclerosis Source Type: news

FDA Warns of Rare Stroke Risk With Multiple Sclerosis Drug
WEDNESDAY, Dec. 5, 2018 -- A new warning has been added to the multiple sclerosis drug Lemtrada (alemtuzumab) after rare reports of patients suffering strokes and tears in the lining of the arteries in the head and neck, the U.S. Food and Drug... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - December 5, 2018 Category: Pharmaceuticals Source Type: news

Medical News Today: Is the ketogenic diet good for multiple sclerosis?
Multiple sclerosis is a chronic condition that affects the nerves. The ketogenic diet, which is a low-carb, high-fat diet, may help protect the body against neurodegeneration, but more research is necessary to confirm this. Learn more about whether the ketogenic diet can benefit people with multiple sclerosis here. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - December 5, 2018 Category: Consumer Health News Tags: Multiple Sclerosis Source Type: news

FDA Warns of Rare Stroke Risk With MS Drug Lemtrada (Alemtuzumab)
WEDNESDAY, Dec. 5, 2018 -- A new warning has been added to the multiple sclerosis drug Lemtrada (alemtuzumab) after rare reports of patients suffering strokes and tears in the lining of the arteries in the head and neck, the U.S. Food and Drug... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - December 5, 2018 Category: General Medicine Source Type: news

Medical News Today: What is Lhermitte's sign?
Lhermitte's sign is sometimes a symptom of multiple sclerosis and other demyelinating conditions. In this article, learn about what causes Lhermitte's sign, its triggers, and how to reduce the risk of experiencing it. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - December 5, 2018 Category: Consumer Health News Tags: Multiple Sclerosis Source Type: news

UCLA scientist looks to space for possible treatment of some neurological diseases
Do astronauts ’ brains get bigger in space?The answer may be found in 10 small containers of human brain cells on board a SpaceX spacecraft  that is scheduled for blast off Dec. 5 for a 16-month voyage to the International Space Station as part of joint project between UCLA and the NASA Ames Research Center.Astronauts on long-duration space missions frequently develop “intracranial hypertension,” or high pressure within the skull, said Araceli Espinosa-Jeffrey, a neurochemist at UCLA’s Intellectual and Developmental Disabilities Research Center in the Jane and Terry Sem...
Source: UCLA Newsroom: Health Sciences - December 5, 2018 Category: Universities & Medical Training Source Type: news

Medical News Today: What to know about multiple sclerosis and mood swings
Multiple sclerosis affects the nerves in the body and may also affect mood. Learn more about the causes of multiple sclerosis mood swings, and the best treatment options, here. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - December 4, 2018 Category: Consumer Health News Tags: Multiple Sclerosis Source Type: news

Balance, gait, and falls in multiple sclerosis - Cameron MH, Nilsag ård Y.
Multiple sclerosis (MS) is a chronic disease of the central nervous system (CNS) and the most widespread nontraumatic cause of disability in young adults around the world. MS occurs in people of all ages, races, and ethnicities. MS is characterized by clin... (Source: SafetyLit)
Source: SafetyLit - December 4, 2018 Category: International Medicine & Public Health Tags: Falls Source Type: news

Multiple Sclerosis | Medscape Multiple Sclerosis | Medscape
Review in-depth clinical information, latest medical news, and guidelines on multiple sclerosis, including advances in treatment and management. (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - November 30, 2018 Category: Consumer Health News Tags: Resource Center Source Type: news

FDA warns about Sanofi MS drug
The FDA is warning consumers about the risk of rare but serious cases of stroke and tears in the lining of arteries in the head and neck associated with Sanofi ’s multiple sclerosis drug, Lemtrada. (Source: PharmaManufacturing.com)
Source: PharmaManufacturing.com - November 30, 2018 Category: Pharmaceuticals Source Type: news

Switch for the regeneration of nerve cell insulation
(Ruhr-University Bochum) An international research team has discovered a mechanism that regulates the regeneration of the insulating layer of neurites. This insulation coating, also referred to as myelin sheath, is crucial for rapid signal transmission among cells. Damages to the myelin sheath, such as are caused by multiple sclerosis, can considerably inhibit the function of the nervous system. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 30, 2018 Category: International Medicine & Public Health Source Type: news

Medical News Today: What is the difference between multiple sclerosis and fibromyalgia?
Multiple sclerosis and fibromyalgia both involve the nervous system, and they can cause similar symptoms, such as pain and fatigue. However, there are crucial differences. Here, learn about the distinctions, as well as symptoms, diagnostic processes, and treatments for each condition. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - November 29, 2018 Category: Consumer Health News Tags: Multiple Sclerosis Source Type: news

Medical News Today: What to know about itching and MS
Itching is one type of dysesthesia, or abnormal sensation, that occurs in people with multiple sclerosis. In this article, learn about why it occurs, as well as how to get relief with home remedies and other treatments. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - November 29, 2018 Category: Consumer Health News Tags: Multiple Sclerosis Source Type: news

FDA warns about rare but serious risks of stroke and blood vessel wall tears with multiple sclerosis drug Lemtrada (alemtuzumab)
The U.S. Food and Drug Administration (FDA) is warning that rare but serious cases of stroke and tears in the lining of arteries in the head and neck have occurred in patients with multiple sclerosis (MS) shortly after they received Lemtrada (alemtuzumab). (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - November 29, 2018 Category: Drugs & Pharmacology Source Type: news

Medical News Today: What is the difference between MS and lupus?
Multiple sclerosis and lupus both involve the immune system, but they cause different symptoms. In this article, learn about the differences and how a doctor makes a diagnosis. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - November 28, 2018 Category: Consumer Health News Tags: Multiple Sclerosis Source Type: news

Ohio State recruits neurology chairman, Neuroscience Institute chief from Michigan
Ohio State University has recruited a leading multiple sclerosis researcher from the University of Michigan as chairman of the medical school's neurology department and to share leadership of Wexner Medical Center ’s Neurological Institute. Dr. Benjamin Segal starts in July after 12 years in Ann Arbor, where he's a neurology professor and director of the MS Center and Program in Neuroimmunology. As neurology chairman, he succeeds Dr. John Kissel, who retired in June after 40 years with the university.… (Source: bizjournals.com Health Care:Pharmaceuticals headlines)
Source: bizjournals.com Health Care:Pharmaceuticals headlines - November 28, 2018 Category: Pharmaceuticals Authors: Carrie Ghose Source Type: news

Chronically Ill, Traumatically Billed: The $123,000 Medicine For MS
Shereese Hickson’s doctor wanted her to try the infusion drug Ocrevus for her multiple sclerosis. Even though Hickson is trained as a medical billing coder, she was shocked to see two doses of the drug priced at $123,019, with her share set at $3,620. (Source: WebMD Health)
Source: WebMD Health - November 28, 2018 Category: Consumer Health News Source Type: news

Low-Dose Aspirin May Help Fight MS, Mouse Study Hints
TUESDAY, Nov. 27, 2018 -- Although the findings are so far only in mice, studies suggest that aspirin -- even the " low-dose " variety -- might help counter multiple sclerosis. Multiple sclerosis (MS) is an autoimmune disorder where aberrant immune... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - November 27, 2018 Category: General Medicine Source Type: news

Discovery opens new opportunities to slow or reverse MS
(University of Wisconsin-Madison) Nerve cells stripped of their insulation can no longer carry vital information, leading to the numbness, weakness and vision problems often associated with multiple sclerosis. A new study shows an overlooked source may be able to replace that lost insulation and provide a new way to treat diseases like MS. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - November 27, 2018 Category: Biology Source Type: news

Aspirin ameliorates experimental autoimmune encephalomyelitis through interleukin-11-mediated protection of regulatory T cells
Multiple sclerosis (MS) is a human disease that results from autoimmune T cells targeting myelin protein that is expressed within the central nervous system. In MS, the number of FoxP3-expressing regulatory T cells (Tregs) is reduced, which facilitates the activation of autoreactive T cells. Because aspirin (acetylsalicylic acid) is the most widely used nonsteroidal anti-inflammatory drug, we examined its immunomodulatory effect in mice with experimental autoimmune encephalomyelitis (EAE), an animal model of MS. We found that low-dose aspirin suppressed the clinical symptoms of EAE in mouse models of both relapsing-remitti...
Source: Signal Transduction Knowledge Environment - November 27, 2018 Category: Science Authors: Mondal, S., Jana, M., Dasarathi, S., Roy, A., Pahan, K. Tags: STKE Research Articles Source Type: news

Ocrelizumab May Help Preserve Hand, Arm Function in PPMS
MONDAY, Nov. 26, 2018 -- For patients with primary progressive multiple sclerosis (PPMS), ocrelizumab reduces progression of upper-extremity (UE) impairment, according to an exploratory analysis published online Nov. 12 in the Multiple Sclerosis... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - November 26, 2018 Category: Pharmaceuticals Source Type: news

Moral judgment: an overlooked deficient domain in multiple sclerosis? - Ayache SS, Chalah MA.
Multiple sclerosis (MS) is a chronic inflammatory and neurodegenerative disease of the central nervous system through which patients can suffer from sensory, motor, cerebellar, emotional, and cognitive symptoms. Although cognitive and behavioral dysfunctio... (Source: SafetyLit)
Source: SafetyLit - November 22, 2018 Category: International Medicine & Public Health Tags: Ergonomics, Human Factors, Anthropometrics, Physiology Source Type: news

Preventing suicidal behaviour in patients with multiple sclerosis: a scoping review - Mellentin A, Stenager E, Stenager E.
INTRODUCTION: Suicidal behavior is a relatively rare occurrence among patients with multiple sclerosis (MS). Nonetheless, it is important to identify and be aware of the constituting risk factors to prevent suicidal behavior among vulnerable patients. Area... (Source: SafetyLit)
Source: SafetyLit - November 21, 2018 Category: International Medicine & Public Health Tags: Suicide and Self-Harm Source Type: news

New neurology studies a 'wakeup call' for global health
(Institute for Health Metrics and Evaluation) Neurology experts from around the world will convene Nov. 27 in New Zealand for a Global Brain Summit examining what one calls 'the greatest challenge of societies in the 21st century.' Among the neurological disorders to be discussed at the Summit are stroke, traumatic brain injury, Alzheimer's disease, Parkinson's disease, multiple sclerosis, and migraine and other headaches. The topics are covered in a new series of 11 papers on neurological disorders in The Lancet Neurology. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - November 21, 2018 Category: Infectious Diseases Source Type: news

FDA warns about severe worsening of multiple sclerosis after stopping the medicine Gilenya (fingolimod)
(Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - November 20, 2018 Category: Drugs & Pharmacology Source Type: news

Charity recruits MS specialist nurses for areas in 'desperate need'
Multiple sclerosis (MS) specialist nurses have been recruited in areas that are in “desperate need of extra support”, the MS Trust has announced. (Source: Nursing Times)
Source: Nursing Times - November 19, 2018 Category: Nursing Source Type: news

MS Relapse Drops During Pregnancy but Rises After
MONDAY, Nov. 19, 2018 -- Rates of multiple sclerosis (MS) relapse decrease during pregnancy but increase postpartum, according to a study published online Oct. 23 in Neurology. Maria K. Houtchens, M.D., from Brigham and Women's Hospital in Boston,... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - November 19, 2018 Category: Pharmaceuticals Source Type: news

The contribution of the instrumented Timed-Up-and-Go test to detect falls and fear of falling in people with multiple sclerosis - Hershkovitz L, Malcay O, Grinberg Y, Berkowitz S, Kalron A.
The objective of our study was to examine the Instrumented Timed-Up-and-Go test (ITUG) in relation to falls and FoF in PwMS. This case-control study comprised... (Source: SafetyLit)
Source: SafetyLit - November 16, 2018 Category: International Medicine & Public Health Tags: Ergonomics, Human Factors, Anthropometrics, Physiology Source Type: news

Shilpa Medicare gets tentative USFDA nod for multiple sclerosis drug
The company's abbreviated new drug application (ANDA) for Dimethyl Fumarate delayed release capsules in the strengths of 120 mg and 240 mg has been granted tentative approval by the USFDA. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - November 16, 2018 Category: Pharmaceuticals Source Type: news

Glenmark gets USFDA nod for multiple sclerosis medication
The approved product is generic version of Sanofi-Aventis US' Aubagio. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - November 16, 2018 Category: Pharmaceuticals Source Type: news

Many Patients Do Not Engage Health Care Provider During MS Relapse
THURSDAY, Nov. 15, 2018 -- The rate and frequency of relapse vary for patients with multiple sclerosis (MS), and many report not visiting a health care provider during relapse, according to a study published in the November issue of Multiple... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - November 15, 2018 Category: Pharmaceuticals Source Type: news

Medical News Today: MS: When good brain cells turn bad
MS causes nerve cells to lose their insulating coating. A new study finds that the cells that construct this coat may also be responsible for its demise. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - November 14, 2018 Category: Consumer Health News Tags: Multiple Sclerosis Source Type: news

Dogs and Portable Morgues: Search Intensifies in Fire Zone
PARADISE, Calif. (AP) — Authorities moved to set up a rapid DNA-analysis system and bring in cadaver dogs, mobile morgues and more search teams in an intensified effort to find and identify victims of the deadliest wildfire in California history, an inferno that killed at least 42 people. Five days after flames all but obliterated the Northern California town of Paradise, population 27,000, officials were unsure of the exact number of missing. But the death toll was almost certain to rise. "I want to recover as many remains as we possibly can, as soon as we can. Because I know the toll it takes on loved ones,&qu...
Source: JEMS: Journal of Emergency Medical Services News - November 13, 2018 Category: Emergency Medicine Authors: Martha Mendoza and Gillian Flaccus, Associated Press Tags: News Operations Source Type: news

Dogs and Portable Morgues: Search Intensifies in Fire Zone
PARADISE, Calif. (AP) — Authorities moved to set up a rapid DNA-analysis system and bring in cadaver dogs, mobile morgues and more search teams in an intensified effort to find and identify victims of the deadliest wildfire in California history, an inferno that killed at least 42 people. Five days after flames all but obliterated the Northern California town of Paradise, population 27,000, officials were unsure of the exact number of missing. But the death toll was almost certain to rise. "I want to recover as many remains as we possibly can, as soon as we can. Because I know the toll it takes on loved ones,&qu...
Source: JEMS Operations - November 13, 2018 Category: Emergency Medicine Authors: Martha Mendoza and Gillian Flaccus, Associated Press Tags: News Operations Source Type: news

New clues to the origin and progression of multiple sclerosis
(Karolinska Institutet) Mapping of a certain group of cells, known as oligodendrocytes, in the central nervous system of a mouse model of multiple sclerosis (MS), shows that they might have a significant role in the development of the disease. The discovery can lead to new therapies targeted at other areas than just the immune system. The results are published in Nature Medicine by researchers at Karolinska Institutet in Sweden. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 12, 2018 Category: International Medicine & Public Health Source Type: news

Medical News Today: What is a TENS unit and does it work?
Some people use a transcutaneous electrical nerve stimulation (TENS) unit to treat pain. This device works by sending electrical impulses through the skin. It may give people relief from the painful symptoms of arthritis, multiple sclerosis, fibromyalgia, endometriosis, and other conditions. Learn more here. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - November 9, 2018 Category: Consumer Health News Tags: Pain / Anesthetics Source Type: news

Multiple sclerosis: Accumulation of B cells triggers nervous system damage
(Technical University of Munich (TUM)) B cells are important in helping the immune system fight pathogens. However, in the case of the neurological autoimmune disease Multiple sclerosis (MS) they can damage nerve tissue. When particular control cells are missing, too many B cells accumulate in the meninges, resulting in inflammation of the central nervous system. A team from the Technical University of Munich (TUM) demonstrated the process using animal and patient samples. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 8, 2018 Category: International Medicine & Public Health Source Type: news

Higher BMI Linked to Lower Brain Volume in MS Higher BMI Linked to Lower Brain Volume in MS
Researchers report that higher BMI is linked to lower brain volume in multiple sclerosis. A second study links healthy eating to better measures of disability, mobility, and cognitive function.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - November 7, 2018 Category: Consumer Health News Tags: Neurology & Neurosurgery News Source Type: news

Medical News Today: MS: How too much salt can cause inflammation
New research discovers the molecular mechanism that explains why a high intake of salt may trigger inflammation and raise the risk of multiple sclerosis. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - November 1, 2018 Category: Consumer Health News Tags: Multiple Sclerosis Source Type: news

Nearly 1 in 5 Patients Referred for MS Are Misdiagnosed Nearly 1 in 5 Patients Referred for MS Are Misdiagnosed
Researchers reveal the prevalence, most common alternative diagnoses, and factors associated with misdiagnosis of patients with an established multiple sclerosis diagnosis.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - October 31, 2018 Category: Consumer Health News Tags: Neurology & Neurosurgery News Source Type: news

Study: Salt consumption factors in multiple sclerosis development
High salt consumption is one of the contributing factors in developing multiple sclerosis, according to a study. (Source: Health News - UPI.com)
Source: Health News - UPI.com - October 30, 2018 Category: Consumer Health News Source Type: news

How salt can trigger inflammation in multiple sclerosis
Cells in a high-salt environment show activation of the beta-catenin/Wnt signaling pathway, which disrupts regulatory T cells and triggers inflammation. (Source: Yale Science and Health News)
Source: Yale Science and Health News - October 29, 2018 Category: Universities & Medical Training Source Type: news

Bringing Precision Diagnostics Home
Patients living with autoimmune diseases such as rheumatoid arthritis, systemic lupus erythematosus (SLE), or multiple sclerosis must see their health practitioners frequently to check the progression of their conditions and their responses to therapies. Monitoring disease activity and severity is crucial so that physicians can help patients get to or stay in remission before long-term damage is done. And since these chronic diseases require a lifetime of care, the testing and doctor visits add up over time. This can be inconvenient and costly. But one company may be changing that dynamic. DxTerity is developing a low-cost...
Source: MDDI - October 26, 2018 Category: Medical Devices Authors: Susan Shepard Tags: IVD Source Type: news

Biogen wins appeal for patent protection of blockbuster drug
Forward Pharma ’s challenge to Biogen’s patent on its blockbuster multiple sclerosis medication Tecfidera has been officially thwarted. (Source: PharmaManufacturing.com)
Source: PharmaManufacturing.com - October 24, 2018 Category: Pharmaceuticals Source Type: news

Forward Pharma loses appeal in Tecfidera patent dispute with Biogen
A U.S. federal appeals court on Wednesday upheld a ruling that Biogen Inc's patents on its blockbuster multiple sclerosis drug Tecfidera are valid, rejecting a challenge by Danish drugmaker Forward Pharma A/S. (Source: Reuters: Health)
Source: Reuters: Health - October 24, 2018 Category: Consumer Health News Tags: healthNews Source Type: news

What is multiple sclerosis? Selma Blair's condition and why it can take decades to diagnose
The 46-year-old actress told fans on Saturday that she has struggled with symptoms for about 15 years - falling, dropping things, foggy memory, and numbness in her left side. (Source: the Mail online | Health)
Source: the Mail online | Health - October 22, 2018 Category: Consumer Health News Source Type: news

What to know about multiple sclerosis
Selma Blair shared in an emotional Instagram post that she's among the 2.3 million people in the world suffering from multiple sclerosis. (Source: ABC News: Health)
Source: ABC News: Health - October 22, 2018 Category: Consumer Health News Tags: Health Source Type: news

WATCH: What is multiple sclerosis?
Multiple sclerosis, or MS, is a chronic disorder where cells from the immune system attack the nerve cells of the central nervous system (CNS). (Source: ABC News: Health)
Source: ABC News: Health - October 22, 2018 Category: Consumer Health News Tags: Health Source Type: news

Selma Blair reveals multiple sclerosis diagnosis
Actress Selma Blair's revelation that she has multiple sclerosis is being met by an outpouring of support. The 46-year-old star disclosed her diagnosis in an emotional Instagram post. The post is bringing new attention to MS. Dr. Tara Narula reports on the symptoms and treatments. (Source: Health News: CBSNews.com)
Source: Health News: CBSNews.com - October 22, 2018 Category: Consumer Health News Source Type: news