Roche ’s BTK inhibitor fenebrutinib significantly reduced brain lesions in people with relapsing forms of multiple sclerosis
Fenebrutinib is an investigational, potent and highly selective oralBruton ’s tyrosine kinase (BTK) inhibitor, the only reversible BTK inhibitor currently in Phase III multiple sclerosis (MS) trialsPhase II study met its primary and secondary endpoints by reducing the total number of new gadolinium-enhancing T1 brain lesions and significantly reducing the total number of new or enlarging T2 brain lesions compared to placeboThe safety profile offenebrutinib was consistent with previous and ongoing clinical trials across more than 2,400 people to dateBasel, 17 May 2023 - Roche (SIX: RO, ROG; OTCQX: RHHBY) announced today p...
Source: Roche Media News - May 17, 2023 Category: Pharmaceuticals Source Type: news
Roche ’s BTK inhibitor fenebrutinib significantly reduced brain lesions in people with relapsing forms of multiple sclerosis
Fenebrutinib is an investigational, potent and highly selective oralBruton ’s tyrosine kinase (BTK) inhibitor, the only reversible BTK inhibitor currently in Phase III multiple sclerosis (MS) trialsPhase II study met its primary and secondary endpoints by reducing the total number of new gadolinium-enhancing T1 brain lesions and significantly reducing the total number of new or enlarging T2 brain lesions compared to placeboThe safety profile offenebrutinib was consistent with previous and ongoing clinical trials across more than 2,400 people to dateBasel, 17 May 2023 - Roche (SIX: RO, ROG; OTCQX: RHHBY) announced today p...
Source: Roche Investor Update - May 17, 2023 Category: Pharmaceuticals Source Type: news
Whites Have Highest Prevalence of Multiple Sclerosis in the United States
TUESDAY, May 16, 2023 -- White individuals have the highest prevalence of multiple sclerosis (MS), according to a study published online May 15 in JAMA Neurology.
Michael Hittle, from the Stanford University School of Medicine in California, and... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - May 16, 2023 Category: Pharmaceuticals Source Type: news
Autoimmune disease increase linked to lifestyle risk factors
A study of over 22 million people has found that autoimmune diseases now affect around one in 10 individuals and could, in some instances, be driven by environmental factors. Some 19 of the most common autoimmune diseases, such as type 1 diabetes, rheumatoid arthritis and multiple sclerosis, have been shown to affect 13% of women... Read moreThe post Autoimmune disease increase linked to lifestyle risk factors appeared first on Nursing in Practice. (Source: Nursing in Practice)
Source: Nursing in Practice - May 10, 2023 Category: Nursing Authors: Megan Ford Tags: Clinical Diabetes Musculoskeletal Source Type: news
Christina Applegate “Probably Not Going To Work On-Camera Again” But Plans To Voice Kelly Bundy In The “Married With Children” Animated Series
Christina Applegate says she’s done with acting in front of a camera after wrapping up Dead to Me amid her multiple sclerosis diagnosis. The Emmy award-winning star opened up about filming the last season of the Netflix dramedy opposite Linda Cardellini when she hinted she was not going to act in…#christinaapplegate #netflix #lindacardellini #vanityfair #applegate #kellybundy #kateysagal #davidfaustino (Source: Reuters: Health)
Source: Reuters: Health - May 7, 2023 Category: Consumer Health News Source Type: news
Teriflunomide Delays MS Symptoms in RIS Teriflunomide Delays MS Symptoms in RIS
For patients with radiologically isolated syndrome (RIS) predictive of multiple sclerosis (MS), teriflunomide reduced the risk of a demyelinating event over a 2-year period in a phase 3 trial.MDedge News (Source: Medscape Radiology Headlines)
Source: Medscape Radiology Headlines - May 5, 2023 Category: Radiology Tags: Neurology & Neurosurgery News Source Type: news
Top 1% Biotech TG Therapeutics Obliterates Bullish Sales Calls
Shares of TG Therapeutics (TGTX) soared Monday after the company more than doubled Wall Street's first-quarter sales expectations. TGTX stock rocketed to a five-month high. In the first three months of the year, multiple sclerosis treatment Briumvi generated $7.8 million in sales, crushing…#tgtherapeutics #briumvi #michaelweiss #weiss #cantorfitzgerald #prakharagrawal #centersformedicare #medicaidservices #medicare #ibddigital (Source: Reuters: Health)
Source: Reuters: Health - May 1, 2023 Category: Consumer Health News Source Type: news
Cannabinoids and multiple sclerosis: a critical analysis of therapeutic potentials and safety concerns - Nouh RA, Kamal A, Abdelnaser A.
Multiple sclerosis (MS) is a complicated condition in which the immune system attacks myelinated axons in the central nervous system (CNS), destroying both myelin and axons to varying degrees. Several environmental, genetic, and epigenetic factors influenc... (Source: SafetyLit)
Source: SafetyLit - May 1, 2023 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news
Outcomes of importance to people with multiple sclerosis, Parkinson's disease and stroke following a falls prevention intervention: a qualitative study to inform a core outcome set - O'Malley N, Coote S, Clifford AM.
PURPOSE: Falls are a major issue for people with neurological conditions, and the evaluation of falls prevention interventions is of high priority. To date, the views of patient groups regarding outcomes of importance have been largely overlooked. The purp... (Source: SafetyLit)
Source: SafetyLit - April 29, 2023 Category: International Medicine & Public Health Tags: Age: Elder Adults Source Type: news
Autonomic response to walk tests is useful for assessing outcome measures in people with multiple sclerosis - Kontaxis S, Laporta E, Garcia E, Guerrero AI, Zabalza A, Matteo M, Lucia R, Simblett S, Weyer J, Hotopf M, Narayan VA, Rashid Z, Folarin AA, Dobson RJB, Buron MD, Leocani L, Cummins N, Vairavan S, Costa GD, Magyari M, S ørensen PS, Nos C, Bailón R, Comi G, Consortium TRC.
OBJECTIVE: The aim of this study was to evaluate the association between changes in the autonomic control of cardiorespiratory system induced by walk tests and outcome measures in people with Multiple Sclerosis (pwMS). METHODS: Electrocardiogram (E... (Source: SafetyLit)
Source: SafetyLit - April 28, 2023 Category: International Medicine & Public Health Tags: Ergonomics, Human Factors, Anthropometrics, Physiology Source Type: news
Treatment May Delay Earliest MS Events
(MedPage Today) -- BOSTON -- Treatment with teriflunomide (Aubagio), a drug approved for relapsing multiple sclerosis (MS), reduced the risk of a clinical event in people with radiologically isolated syndrome (RIS), the phase III TERIS trial... (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - April 26, 2023 Category: Neurology Source Type: news
[Ad hoc announcement pursuant to Art. 53 LR] Roche reports strong sales growth in base business of both divisions in the first quarter; Group sales decline due to expected drop in demand for COVID-19 tests
As expected, significantly lower demand for COVID-19 tests leads to a decrease inGroup sales (-3%1 at constant exchange rates [CER] and -7% in Swiss francs); excluding this effect, Group sales grow 8%Pharmaceuticals Divisionsales up 9%; strong demand for newer medicines; Vabysmo for severe eye diseases is already the strongest growth driverDiagnostics Division base business grows 4%, whiledivisional salesare 28% lower due to exceptionally high demand for COVID-19 tests in the first quarter of 2022Highlights in the first quarter:US approval of Polivy (first-line treatment for an aggressive form of blood cancer)EU approva...
Source: Roche Investor Update - April 26, 2023 Category: Pharmaceuticals Source Type: news
[Ad hoc announcement pursuant to Art. 53 LR] Roche reports strong sales growth in base business of both divisions in the first quarter; Group sales decline due to expected drop in demand for COVID-19 tests
Basel, 26 April 2023As expected, significantly lower demand for COVID-19 tests leads to a decrease inGroup sales (-3%1 at constant exchange rates [CER] and -7% in Swiss francs); excluding this effect, Group sales grow 8%Pharmaceuticals Divisionsales up 9%; strong demand for newer medicines; Vabysmo for severe eye diseases is already the strongest growth driverDiagnostics Division base business grows 4%, whiledivisional salesare 28% lower due to exceptionally high demand for COVID-19 tests in the first quarter of 2022Highlights in the first quarter:US approval of Polivy (first-line treatment for an aggressive form of blo...
Source: Roche Media News - April 26, 2023 Category: Pharmaceuticals Source Type: news
Novel MS Drug Good as Gold in Phase II Study
(MedPage Today) -- BOSTON -- Gold nanoparticles in an oral suspension helped patients with relapsing multiple sclerosis (MS) preserve ocular and overall function when added to standard medications in a phase II trial, a researcher said here... (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - April 25, 2023 Category: Neurology Source Type: news
Used Early, Drug Might Delay MS Symptom Onset
FRIDAY, April 21, 2023 – Growing numbers of people have MRI brain scans to find out what ' s causing their headaches, see if they have a concussion or for another reason, when a doctor may spot the tell-tale lesions of multiple sclerosis... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - April 21, 2023 Category: General Medicine Source Type: news
