Cardio-cerebrovascular disease history complicates hematopoietic cell transplant outcomes
(Cactus Communications) Transplanting hematopoietic stem cells to treat cancers and other conditions carries with it the risk of developing cardio-cerebrovascular diseases (CCVD)--disorders affecting the blood vessels of the heart and brain. Although research on post-transplant CCVD is extensive, there is paucity of knowledge on the effects of pre-transplant CCVD on transplant outcomes. Now researchers in China suggest pre-transplant CCVD indirectly affects patient mortality and survival following transplant through their strong association with post-transplant CCVD. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 22, 2021 Category: International Medicine & Public Health Source Type: news

A substance from Saussurea controversa will help bone tissue regeneration
(Immanuel Kant Baltic Federal University) Scientists from the IKBFU with colleagues obtained calcium chelidonate via a semisynthesis. This substance accelerates the transformation of stem cells into osteoblasts - its use is promising as a treatment for bone diseases. A plant, Saussurea controversa, used in medicine since ancient times, served as a source for synthesis. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 20, 2021 Category: International Medicine & Public Health Source Type: news

Secrets and pies: the battle to get lab-grown meat on the menu
Sustainable alternatives to livestock farming are being held back by patents, a reluctance to share research and lack of government supportNot a week goes by without Elliot Swartz receiving at least one request from researchers asking him where they can find cell lines (a cell culture developed from a single cell) for use in cellular agriculture – an essential tool for creating lab-grown meat. “One of the most important things that cell lines offer is that they enable researchers to just get started in this new field,” says Swartz, who works in New York as a senior scientist at theGood Food Institute (GFI...
Source: Guardian Unlimited Science - July 18, 2021 Category: Science Authors: Jack McGovan Tags: Stem cells Biology Research and development Meat industry Food Technology Science Source Type: news

Ruxolitinib Best Option When Glucocorticoids Fail Against Chronic GVHD Ruxolitinib Best Option When Glucocorticoids Fail Against Chronic GVHD
When chronic graft-versus-host disease follows an allogeneic stem-cell transplant, and it's either resistant to standard glucocorticoid therapy or dependent on glucocorticoids, according to the REACH3 trial.Reuters Health Information (Source: Medscape Transplantation Headlines)
Source: Medscape Transplantation Headlines - July 16, 2021 Category: Transplant Surgery Tags: Allergy & Clinical Immunology News Source Type: news

3D " assembloid " shows how SARS-CoV-2 infects brain cells
(University of California - San Diego) Researchers at UC San Diego School of Medicine and Rady Children's Institute for Genomic Medicine have produced a stem cell model that demonstrates a potential route of entry of SARS-CoV-2, the virus that causes COVID-19, into the human brain. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - July 16, 2021 Category: Biology Source Type: news

Mesenchymal Stem Cells in COVID-19 Mesenchymal Stem Cells in COVID-19
Might mesenchymal stem cells have a therapeutic role in critically ill patients suffering from COVID-19? This paper looks at the current state of research.Laboratory Medicine (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - July 14, 2021 Category: Consumer Health News Tags: Pathology & Lab Medicine Journal Article Source Type: news

Pierre Vanderhaeghen awarded for his pioneering research
(Spanish National Research Council (CSIC)) The jury of the 10th edition of the Remedios Caro Almela Prize for Research in Developmental Neurobiology has decided to award this prize to Pierre Vanderhaeghen, director of the stem cell and developmental neurobiology laboratory of the VIB-KU Leuven Center for Research on the Brain and its Diseases (Belgium). (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - July 14, 2021 Category: Biology Source Type: news

Regulatory Affairs Expert Ana Sousa Joins Aspen Neuroscience as Senior Vice President
SAN DIEGO, July 13, 2021 -- (Healthcare Sales & Marketing Network) -- Aspen Neuroscience, Inc., a private biotechnology company developing the first autologous neuron replacement therapies to treat Parkinson's disease (PD), announced today that Ana Sousa ... Regenerative Medicine, Neurology, Personnel Aspen Neuroscience, Parkinson, stem cell (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - July 13, 2021 Category: Pharmaceuticals Source Type: news

Sensing " junk " RNA after chemotherapy enhances blood regeneration
(Max Planck Institute of Immunobiology and Epigenetics) Scientists from the MPI-IE reveal that during hematopoietic regeneration, RNA expressed from a part of the genome considered " junk DNA " is used by hematopoietic stem cells to get activated and proliferate. The study published in the scientific journal Nature Cell Biology shows that these so-called transposable elements make RNA after chemotherapy and activate an immune receptor which induces inflammatory signals enhancing hematopoietic stem cell cycling and thus participating in the regeneration of the hematopoietic system. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 12, 2021 Category: International Medicine & Public Health Source Type: news

Euro 2020: Man missed England win to donate stem cells
Sam Astley's partner won tickets but he says there was "no way" he was going to delay the donation. (Source: BBC News | Health | UK Edition)
Source: BBC News | Health | UK Edition - July 8, 2021 Category: Consumer Health News Source Type: news

Mayo Clinic Minute: Why bone marrow donor diversity is needed
Bone marrow transplants are procedures that infuse healthy blood stem cells into your body to replace damaged or diseased bone marrow. Just like people in need of solid organ transplants, such as hearts or kidneys, people in need of a bone marrow transplant have to find a matching donor. Dr. Ernesto Ayala, a Mayo Clinic hematologist and oncologist, says bone marrow donations from people of all races and ethnicities are essential in order to help… (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - July 8, 2021 Category: Databases & Libraries Source Type: news

Thomas Rando named director of UCLA Broad Stem Cell Research Center
Dr. Thomas Rando, a renowned neurologist and stem cell biologist, has been named director of the  Eli and Edythe Broad Center of  Regenerative Medicine and Stem Cell Research at UCLA.Rando, who was chosen after an international search, is currently a professor of neurology and neurological sciences at the medical school at Stanford University, where he also serves as director of the Glenn Center for the Biology of Aging and deputy director of the Stanford Center on Longevity. In addition, he is chief of neurology at the  Veterans Affairs Palo Alto Health Care System.His appointment is effective Oct. 1.&ldquo...
Source: UCLA Newsroom: Health Sciences - July 7, 2021 Category: Universities & Medical Training Source Type: news

Uncovering the genetic mechanism behind Rett syndrome
(Kyushu University) Kyushu University researchers found that the main gene that causes Rett syndrome, MeCP2, controls the differentiation pattern of neural stem cells through the microRNA miR-199a. Dysfunction in MeCP2 or miR-199a cause neural stem cells to produce more astrocytes than neurons. Furthermore, the researchers found that miR-199a mediates the production of Smad1, a downstream transcription factor of bone morphogenetic protein (BMP) signaling. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 2, 2021 Category: International Medicine & Public Health Source Type: news

NIDCR's Summer 2021 E-Newsletter
Having trouble viewing this email? View it as a Web page. NIDCR's Summer 2021 E-Newsletter In this issue: NIDCR News Funding Opportunities & Related Notices NIH/HHS News Subscribe to NICDR News Science Advances   Grantee News   NIDCR News NIDCR to Release Report on Oral Health in America As a 20-year follow-up to the seminal Oral Health in America: A Report of the Surgeon General, NIDCR will release Oral Health in America: Advances and Challenges in the fall of 2021. The report will illuminate new directions...
Source: NIDCR Science News - July 1, 2021 Category: Dentistry Source Type: news

From meadow to plate: The cultured meat that replaces animals with grass
(University of Bath) An affordable lab system that uses grass blades to turn cells into cultured meat, by creating a scaffold that animal stem cells can attach to and grow on, has been developed at the University of Bath in the UK. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - July 1, 2021 Category: Biology Source Type: news

Stem Cell Transplant Treats Parkinson ’s Disease in Monkeys
Personalized stem cells improved motor symptoms and depression signs in monkeys modeling Parkinson ’s disease, paving the way for trials in human patients. (Source: The Scientist)
Source: The Scientist - July 1, 2021 Category: Science Tags: Sponsored Article Source Type: news

Stem Cell Transplant Treats Parkinson & rsquo;s Disease in Monkeys
(Source: The Scientist)
Source: The Scientist - July 1, 2021 Category: Science Tags: Sponsored Article Source Type: news

Human stem cells enable model to test drug impact on brain's blood barrier
(KTH, Royal Institute of Technology) Using an experimental model to simulate the blood-brain barrier, scientists in Sweden reported in unprecedented detail how antioxidants protect the brain from inflammation caused by such neurodegenerative diseases as Alzheimer's and Parkinsons. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 30, 2021 Category: International Medicine & Public Health Source Type: news

In a dish, a mouse, crafted from stem cells, begins to form
(University of Virginia Health System) New advances in stem cell research will help scientists battle diseases, develop drugs and, eventually, grow organs for transplant. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - June 29, 2021 Category: Biology Source Type: news

Blood stem cells make brain tumors more aggressive
(German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ)) Blood stem cells make brain tumors more aggressiveFor the first time, scientists from the German Cancer Consortium (DKTK) partner site in Essen/D ü sseldorf have discovered stem cells of the hematopoietic system in glioblastomas, the most aggressive form of brain tumor. These hematopoietic stem cells promote division of the cancer cells and at the same time suppress the immune response against the tumor. This surprising discovery might open up new possibilities for developing more effective immunotherapies against these malignant brain tumors. (S...
Source: EurekAlert! - Cancer - June 28, 2021 Category: Cancer & Oncology Source Type: news

Differences in human, mouse brain cells have important implications for disease research
FINDINGSA UCLA-led study comparing brain cells known as astrocytes in humans and mice found that mouse astrocytes are more resilient to oxidative stress, a damaging imbalance that is a mechanism behind many neurological disorders. A lack of oxygen triggers molecular repair mechanisms in these mouse astrocytes but not in human astrocytes. In contrast, inflammation activates immune-response genes in human astrocytes but not mouse astrocytes.BACKGROUNDAlthough the mouse is a ubiquitous laboratory model used in research for neurological diseases, results from studies in mice are not always applicable to humans. In fact, more t...
Source: UCLA Newsroom: Health Sciences - June 25, 2021 Category: Universities & Medical Training Source Type: news

Sleeper cells: Newly discovered stem cell resting phase could put brain tumors to sleep
(Arizona State University) Arizona State University biomedical engineering researchers developed a new cell classifier tool that takes a higher-resolution look at the life cycle of neuroepithelial stem cells, which led to the discovery and exploration of a new resting phase called Neural G0. This knowledge could help scientists to better understand glioma brain tumors and develop new methods of treatment. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 25, 2021 Category: International Medicine & Public Health Source Type: news

Novel risk score for predicting blood cancer relapse
(Cactus Communications) Several patients suffering from leukemia, who have undergone stem cell transplantation, are at a risk of relapse, owing to varied reasons. Before the inevitable, what if it is possible to predict this situation, and take appropriate medical measures? A group of researchers in China appear to have solved this challenge by developing a novel risk score for leukemia relapse prediction, according to a study published in Chinese Medical Journal. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 24, 2021 Category: International Medicine & Public Health Source Type: news

Caryn Peterson Joins Aspen Neuroscience Board of Directors
SAN DIEGO, June 23, 2021 -- (Healthcare Sales & Marketing Network) -- Aspen Neuroscience, Inc., a private biotechnology company developing the first autologous neuron replacement therapies to treat Parkinson's disease (PD), announced today that Caryn Pete... Devices, Regenerative Medicine, Neurology, Personnel Aspen Neuroscience, Parkinson, stem cell (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - June 23, 2021 Category: Pharmaceuticals Source Type: news

Research provides a roadmap to HIV eradication via stem cell therapy
(University of California - Davis Health) A groundbreaking study found that stem cells reduce the amount of virus causing AIDS, boost the body's antiviral immunity, and restore the gut's lymphoid follicles damaged by HIV. It provided a roadmap for multi-pronged HIV eradication strategies. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - June 23, 2021 Category: Infectious Diseases Source Type: news

Cedars-Sinai awarded $11.99 million for ALS clinical trial
(Cedars-Sinai Medical Center) Cedars-Sinai has been awarded $11.99 million by California's stem cell agency to launch a clinical trial testing a potential gene and stem cell therapy for amyotrophic lateral sclerosis (ALS). (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - June 23, 2021 Category: Biology Source Type: news

AI spots healthy stem cells quickly and accurately
(Tokyo Medical and Dental University) Researchers from Tokyo Medical and Dental University (TMDU) have designed a deep learning-based system that accurately identifies individual skin stem cells grown under artificial conditions and tracks their motion. Using this system to perform quality control of stem cell cultures could improve the speed and efficiency of growing skin grafts for use in regenerative medicine and may also be useful for other types of stem cell cultures. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 23, 2021 Category: International Medicine & Public Health Source Type: news

Republican senators raise concerns over research on human-animal chimeras
(Natural News) Republican lawmakers are raising concerns about scientists growing monkey embryos injected with human cells. Back in April, the Salk Institute for Biological Studies in La Jolla, California, said that it participated in an experiment with Chinese researchers and managed to grow embryos that combined both monkey cells and human stem cells. Although none of... (Source: NaturalNews.com)
Source: NaturalNews.com - June 22, 2021 Category: Consumer Health News Source Type: news

Stanford spinout's latest deal looks to unlock new fix for sickle cell disease
The initial Stanford research, studying how to make more bone marrow more receptive to gene therapies and stem cell transplants and less toxic for patients, was backed by nearly $23 million in grants from California's stem cell research funding agency. (Source: bizjournals.com Health Care:Physician Practices headlines)
Source: bizjournals.com Health Care:Physician Practices headlines - June 21, 2021 Category: American Health Authors: Ron Leuty Source Type: news

Predicting resistance to anticancer drugs
(VIB (the Flanders Institute for Biotechnology)) Cancer cells can develop resistance to therapy through both genetic and non-genetic mechanisms. But it is unclear how and why one of these routes to resistance prevails. Understanding this 'choice' by the cancer cells may help us devise better therapeutic strategies. Now, the team of Prof. Jean-Christophe Marine (VIB-KU Leuven Center for Cancer Biology) shows that the presence of certain stem cells correlates with the development of nongenetic resistance mechanisms. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 17, 2021 Category: International Medicine & Public Health Source Type: news

Engineered NK cells can eliminate glioblastoma stem cells
(University of Texas M. D. Anderson Cancer Center) Preclinical research finds that glioblastoma stem cells can be targeted by NK cells, but they are able to evade immune attack by releasing TFG-β. Deleting the TFG-β receptor in NK cells renders them resistant to this and restores their anti-tumor activity. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 17, 2021 Category: International Medicine & Public Health Source Type: news

Good Response to COVID-19 Vaccine After HSCT and CAR T-cell Tx Good Response to COVID-19 Vaccine After HSCT and CAR T-cell Tx
A small study shows relatively good responses among patients with blood cancers who underwent allogeneic hematopoeitic stem cells transplant (HSCT) and CAR T-cell therapy.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - June 16, 2021 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

The ISSCR 2021 Annual Meeting starts 21 June
(International Society for Stem Cell Research) The ISSCR 2021 Annual Meeting is the most comprehensive gathering of scientists in stem cell research and regenerative medicine in the world. Taking place 21-26 June 2021, this hallmark event offers attendees the opportunity share knowledge, collaborate, and network in an interactive virtual meeting experience. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 16, 2021 Category: International Medicine & Public Health Source Type: news

Stem cells may hold a key to developing new vaccines against COVID-19
(Elsevier) The SARS-CoV-2 virus that causes COVID-19 may have the ability to reactivate dormant tuberculosis (TB). In a novel study scientists report in The American Journal of Pathology that infection with a specific coronavirus strain reactivated dormant Mycobacterium tuberculosis (MTB) in mice. This knowledge may help to develop new vaccines for COVID-19 and avoid a potential global tuberculosis epidemic. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - June 16, 2021 Category: Infectious Diseases Source Type: news

Cancer cells fight for their footing by using an ageing gene
Researchers at the University of Helsinki and the Beatson Institute for Cancer Research in Glasgow have discovered how mutated cells promote their chances to form cancer. Typically, the accumulation of harmful cells is prevented by active competition between multiple stem cells in intestinal glands, called crypts. (Source: World Pharma News)
Source: World Pharma News - June 15, 2021 Category: Pharmaceuticals Tags: Featured Research Research and Development Source Type: news

Main gland in hormonal system ages due to process that can potentially be slowed down
(KU Leuven) Stem cell biologist Hugo Vankelecom (KU Leuven) and his colleagues have discovered that the pituitary gland in mice ages as the result of an age-related form of chronic inflammation. It may be possible to slow down this process or even partially repair it. The researchers have published their findings in PNAS. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - June 15, 2021 Category: International Medicine & Public Health Source Type: news

A frozen leap forward
(University of California - Santa Barbara) Scientists at UC Santa Barbara, University of Southern California (USC) and biotechnology company Regenerative Patch Technologies LLC (RPT) have reported new methodology for preservation of RPT's stem cell-based therapy for age-related macular degeneration (AMD). (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - June 14, 2021 Category: Biology Source Type: news

Hair follicles heal blisters at personal cost
(Hokkaido University) A team of scientists has shown that the healing of skin blisters is driven by hair follicle stem cells, which delay their own development in the process. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 14, 2021 Category: International Medicine & Public Health Source Type: news

Janssen Announces Results from Phase 3 MAIA Study Showing Significant Overall Survival Benefits for Treatment with DARZALEX ® (daratumumab) in Patients with Newly Diagnosed Multiple Myeloma Who are Transplant Ineligible
Raritan, N.J., June 12, 2021 – The Janssen Pharmaceutical Companies of Johnson & Johnson announced overall survival (OS) results from the Phase 3 MAIA (NCT02252172) study showing the addition of DARZALEX® (daratumumab) to lenalidomide and dexamethasone (D-Rd) resulted in a statistically significant survival benefit over lenalidomide and dexamethasone (Rd) alone in patients with newly diagnosed multiple myeloma (NDMM) who were ineligible for autologous stem cell transplant (ASCT) and were treated to progression.[1] These data were featured in the European Hematology Association (EHA) 2021 Virtual Press Briefin...
Source: Johnson and Johnson - June 12, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news

Stem Cell Transplant Reviewed for Peripheral T - Cell Lymphoma
Three - and five - year overall survival similar with allogeneic or autologous HSCT, but transplant - related mortality higher with allogeneic HSCT (Source: The Doctors Lounge - Oncology)
Source: The Doctors Lounge - Oncology - June 10, 2021 Category: Cancer & Oncology Tags: Oncology, Pathology, Journal, Source Type: news

Scientists Discover "Gorditas" and Other Novel Brain Cell Types
A pool of neural stem cells that ordinarily lies dormant in the brains of adult mice spawns two types of never-before-documented glial cells when artificially reactivated, potentially pointing to a... (Source: The Scientist)
Source: The Scientist - June 10, 2021 Category: Science Tags: News & Opinion Source Type: news

Stem Cell Transplant Reviewed for Peripheral T-Cell Lymphoma
THURSDAY, June 10, 2021 -- For patients with refractory or relapsed peripheral T-cell lymphoma (R/R-PTCL), three- and five-year overall survival (OS) and progression-free survival (PFS) are similar with allogeneic or autologous hematopoietic stem... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - June 10, 2021 Category: Pharmaceuticals Source Type: news

Drug commonly used as antidepressant helps fight cancer in mice
A class of drug called monoamine oxidase inhibitors is commonly prescribed to treat depression; the medications work by boosting levels of serotonin, the brain ’s “happiness hormone.”A new study by UCLA researchers suggests that those drugs, commonly known as MAOIs, might have another health benefit: helping the immune system attack cancer. Their findings are reported in two papers, which are published in the journals Science Immunology and Nature Communications.“MAOIs had not been linked to the immune system’s response to cancer before,” saidLili Yang, senior author of the study and a m...
Source: UCLA Newsroom: Health Sciences - June 10, 2021 Category: Universities & Medical Training Source Type: news

A new mechanism behind continuous stem cell activity in plants
(Kobe University) An inter-university research group has succeeded in constructing the gene expression network behind the vascular development process in plants. They achieved this by performing bioinformatics analysis using the 'VISUAL' tissue culture platform, which generates vascular stem cells from leaf cells. In this network, they also discovered a new BES/BZR transcription factor, BEH3, and illuminated its role in vascular cell maintenance. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 10, 2021 Category: International Medicine & Public Health Source Type: news

ViaCyte Announces Closing of $45 Million Financing to Advance Broadest Portfolio of Stem Cell-Derived Therapies for Type 1 Diabetes
Brings the Company's total Series D funding to more than $115 million SAN DIEGO, June 9, 2021 -- (Healthcare Sales & Marketing Network) -- ViaCyte, Inc., a clinical-stage regenerative medicine company, today announced the closing of a $45 million finan... Regenerative Medicine, Venture Capital ViaCyte, cell therapy, diabetes (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - June 9, 2021 Category: Pharmaceuticals Source Type: news

Bayer to advance two first-of-its-kind cell and gene therapies for Parkinson's disease
Bayer AG announced today that BlueRock Therapeutics (BlueRock), a clinical stage biopharmaceutical company and wholly-owned subsidiary of Bayer AG, successfully administered the first dose of its pluripotent stem cell-derived dopaminergic neurons, named DA01, to a Parkinson's disease patient in their open-label Phase 1 clinical study. (Source: World Pharma News)
Source: World Pharma News - June 8, 2021 Category: Pharmaceuticals Tags: Featured Bayer Business and Industry Source Type: news

Research advances one step closer to stem cell therapy for type 1 diabetes
(Salk Institute) Scientists at the Salk Institute are developing a promising approach for treating type 1 diabetes by using stem cells to create insulin-producing cells (called beta cells) that could replace nonfunctional pancreatic cells. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 7, 2021 Category: International Medicine & Public Health Source Type: news

Odds of stem cell transplant restoring fertility are as random as a coin toss -- until now
(Hiroshima University) The chances of restoring fertility through sperm stem cell transplant are as random as a coin toss. But a team of scientists developed a new strategy that serves as a " weighted coin " that can favorably rig the odds to achieve outcomes where fertility is successfully restored. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - June 7, 2021 Category: Biology Source Type: news

Stem cell therapy could reverse Type 2 diabetes for some, study finds
A Vietnamese medical study has found stem cell therapy using cells produced from a patient's own bone marrow may reverse Type 2 diabetes in certain groups. (Source: Health News - UPI.com)
Source: Health News - UPI.com - June 3, 2021 Category: Consumer Health News Source Type: news

Genetic base editing treats sickle cell disease in mice
(Broad Institute of MIT and Harvard) Sickle cell disease leads to chronic pain, organ failure, and early death in patients worldwide. A team led by Broad Institute of MIT and Harvard and St. Jude Children's Research Hospital has demonstrated a gene editing approach that efficiently corrects the mutation underlying SCD in patient blood stem cells and in mice. This treatment rescued disease symptoms in animal models, enabling long-lasting production of healthy blood cells, and could inspire a therapeutic strategy for SCD. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 3, 2021 Category: International Medicine & Public Health Source Type: news