End-of-life care program at UCLA benefited dying patients and loved ones despite COVID restrictions
A program offered by UCLA Health ’s intensive care units is providing meaningful and compassionate support for dying patients and their families, despite the challenges brought about by COVID-19. A study about the initiative, published in the journalCritical Care Explorations, is the first to show empirically that a palliative care program could be adapted — and even expanded — during the pandemic. It also could serve as a case study for improving end-of-life care during an era when visiting restrictions and infection control have introduced extraordinary new challenges for health care providers.Rese...
Source: UCLA Newsroom: Health Sciences - October 18, 2021 Category: Universities & Medical Training Source Type: news

A decade after gene therapy, children born with deadly immune disorder remain healthy
Over a decade ago, UCLA physician-scientists began using a pioneering gene therapy they developed to treat children born with a rare and deadly immune system disorder.They now report that the effects of the therapy appear to be long-lasting, with 90% of patients who received the treatment eight to 11 years ago still disease-free.ADA-SCID, oradenosine deaminase –deficient severe combined immunodeficiency, is caused by mutations in the gene that creates the ADA enzyme, which is essential to a functioning immune system. For babies with the disease, exposure to everyday germs can be fatal, and if untreated, most will die...
Source: UCLA Newsroom: Health Sciences - October 15, 2021 Category: Universities & Medical Training Source Type: news

A visit from a social robot improves hospitalized children ’s outlook
A new  study from UCLA finds a visit from human-controlled robot encourages a positive outlook and improves medical interactions for children who are hospitalized.Robin is a social companion robot that stands about 4 feet tall and has the capabilities to move, talk and play with others while being remotely controlled by humans. Specialists fromUCLA Mattel Children ’s Hospital’s Chase Child Life Program conducted hour-long video visits with young patients using Robin, comparing it to interactions using a standard computer tablet, from October 2020 to April 2021.At the conclusion of the study perio...
Source: UCLA Newsroom: Health Sciences - October 8, 2021 Category: Universities & Medical Training Source Type: news

Concussions and kids: Project co-led by UCLA gets $10 million grant from NIH
A research project co-led by theUCLA Steve Tisch BrainSPORT Programaimed at improving the assessment and treatment of concussions in school-aged children has been awarded $10 million by the National Institute of Neurological Disorders and Stroke, part of the National Institutes of Health.The grant to the Four Corners Youth Consortium, agroup of academic medical centers studying pediatric concussions, will supportConcussion Assessment, Research and Education for Kids, or CARE4Kids, a multisite study that will enroll more than 1,300 children and teens nationwide, including an estimated 240 in Southern California.CARE4Kids re...
Source: UCLA Newsroom: Health Sciences - October 7, 2021 Category: Universities & Medical Training Source Type: news

UCLA study maps major circuit in the mouse brain
A UCLA study using mice reveals new insights into the wiring of a major circuit in the brain that is attacked by Parkinson ’s and Huntington’s diseases. The findings could hone scientists’ understanding of how diseases arise in the human brain and pinpoint new targets for treatment.Published today in Nature, the research is part of a package of 17 articles  bytheBRAIN Initiative Cell Census Network. The national consortium of neuroscientists aims to unlock the mysteries of the primary motor cortex, a part of the mammalian brain that controls movement.With funding from the National Institute of Mental...
Source: UCLA Newsroom: Health Sciences - October 6, 2021 Category: Universities & Medical Training Source Type: news

$6.2 million NIH grant to support UCLA study of how COVID-19 causes multiple organ failure
Researchers from the  Eli and Edythe Broad Center of  Regenerative Medicine and Stem Cell Research at UCLA have received a $6.2 million grant from the National Institutes of Health to study how the SARS-CoV-2 virus causes damage throughout the body.The Director ’s Transformative Research Award was presented through the NIH’s prestigious High Risk, High Reward program, which supports creative and unconventional approaches to major challenges in biomedical and behavioral research. What makes SARS-CoV-2, the virus that causes COVID-19, so dangerous for some people is that although it is a respi...
Source: UCLA Newsroom: Health Sciences - October 5, 2021 Category: Universities & Medical Training Source Type: news

mRNA COVID vaccines highly effective at preventing symptomatic infection in health workers
COVID-19 are highly effective in preventing symptomatic illness among health care workers in real-world settings.The study, published in the New England Journal of Medicine, found that health care personnel who received a two-dose regimen of Pfizer –BioNTech vaccine had an 89% lower risk for symptomatic illness than those who were unvaccinated. For those who received the two-dose regimen of the Moderna vaccine, the risk was reduced by 96%.The researchers also found that the vaccines appeared to work just as well for people who are over age 50, are in racial or ethnic groups that have been disproportionately affected ...
Source: UCLA Newsroom: Health Sciences - October 5, 2021 Category: Universities & Medical Training Source Type: news

UCLA raises $611 million in 2020 –21, supporting students and advancing critical research
UCLA raised more than $611 million in gifts and pledges in the fiscal year ending June 30, exceeding its annual goal and drawing donors from all 50 states and 72 countries.“Generous donors at all levels have continued to partner with UCLA to effect meaningful change on campus, in the community and around the world,” said Chancellor Gene Block. “Despite a challenging year, our friends have once again demonstrated their extraordinary commitment to UCLA’s mission of education, research and service.”In response to conditions created by the COVID-19 pandemic, many donors focused on students ’...
Source: UCLA Newsroom: Health Sciences - October 4, 2021 Category: Universities & Medical Training Source Type: news

Lara Cushing named to new Fielding Presidential Chair in Health Equity
Lara Cushing, an assistant professor of environmental health sciences whose work focuses on issues of environmental justice, has been appointed the inaugural holder of the Jonathan and Karin Fielding Presidential Chair in Health Equity at theUCLA Fielding School of Public Health.The endowed chair was established by  Dr. Jonathan Fielding, a national public health leader and distinguished professor-in-residence at the Fielding School, and Karin Fielding, also a longtime public health advocate, to support the work of an early-career faculty member who is developing innovative ways to solve persistent health dis parities...
Source: UCLA Newsroom: Health Sciences - October 1, 2021 Category: Universities & Medical Training Source Type: news

Black patients ’ Lyme disease often diagnosed late, possibly due to missed signs
FINDINGSA UCLA study suggests that many physicians may not have the knowledge or training to properly recognize how Lyme disease appears on the skin of Black patients. The disease, caused by the tick-borne Borrelia bacterium, generally begins with a bull ’s-eye–shaped rash on the skin, along with fever, headache, chills and muscle pain; if not diagnosed promptly and treated with antibiotics, it can lead to more severe and long-lasting symptoms.UCLA ’s Dr. Dan Ly found that approximately 1 in 3 Black patients who were newly diagnosed with Lyme disease already had related neurological complications such as ...
Source: UCLA Newsroom: Health Sciences - October 1, 2021 Category: Universities & Medical Training Source Type: news

Ophthalmologist Patricia Bath inducted posthumously into National Inventors Hall of Fame
Dr. Patricia Bath, the first female faculty member in ophthalmology at the David Geffen School of Medicine at UCLA, has been inducted posthumously into the National Inventors Hall of Fame.She and Marian Croak,  vice president of engineering at Google, are the first Black women to be honored by the organization, an achievement noted byNational Public Radio, CNN andFast Company. “Dr. Bath was a trailblazer for women and minorities in the field of ophthalmology,” said Dr. Bartly Mondino, department chair of ophthalmology and director of the UCLA Stein Eye Institute.Bath is credited with in...
Source: UCLA Newsroom: Health Sciences - September 29, 2021 Category: Universities & Medical Training Source Type: news

UCLA Broad Stem Cell Research Center receives $5 million CIRM grant for research training program
TheEli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLAhas been awarded $5 million by the California Institute for Regenerative Medicine, the state ’s stem cell agency, to train young scientists and physicians to become leaders in the stem cell and regenerative medicine field.The five-year grant will enable the center to expand its Stem Cell Training Program, which was established in 2006 and funded by CIRM until 2015, when the agency changed its funding priorities. Since then, the program has been sustained by philanthropy. With the passage of Proposition 14 last fall, however, CIRM ha...
Source: UCLA Newsroom: Health Sciences - September 23, 2021 Category: Universities & Medical Training Source Type: news

UCLA research reveals how a year of change affected Californians ’ health
Although more Californians than ever had health insurance in 2020, disparities in access to health care among the state ’s racial and ethnic groups was magnified during a year of unprecedented challenges and changes.Those are among the key findings of the latestCalifornia Health Interview Survey, which is conducted by theUCLA Center for Health Policy Research. The survey included responses from 22,661 California households, including 21,949 adults, 1,365 adolescents and 3,548 children.“This is one of the most important data releases in the survey’s 20-year history because it sheds light on how impactful t...
Source: UCLA Newsroom: Health Sciences - September 22, 2021 Category: Universities & Medical Training Source Type: news

UCLA receives $13 million contract to expand COVID-19 testing
A new $13.3 million contract from the National Institutes of Health ’s Rapid Acceleration of Diagnostics initiative, or RADx, will enable theDavid Geffen School of Medicine at UCLA to expand its capacity to process COVID-19 tests.UCLA ’s diagnostic laboratory will be able to process up to 150,000 COVID-19 tests per day usingSwabSeq, a sequencing technology developed at UCLA. The technology pools thousands of saliva samples and returns individual test results in less than 24 hours.“UCLA developed SwabSeq and brought the technology to market in only six months — a process that...
Source: UCLA Newsroom: Health Sciences - September 20, 2021 Category: Universities & Medical Training Source Type: news

Do doctors treat pain differently based on their patients ’ race?
Physicians prescribed opioids more often to their white patients who complained of new-onset low back pain than to their Black, Asian and Hispanic patients during the early days of the national opioid crisis, when prescriptions for these powerful painkillers were surging but their dangers were not fully apparent,according to a UCLA study.The findings suggest that doctors may have commonly dispensed pain treatments unequally based on race and ethnicity. The study shows that physicians were more likely to prescribe non-steroidal anti-inflammatory drugs, or NSAIDs — a less-powerful alternative — to their patients ...
Source: UCLA Newsroom: Health Sciences - September 10, 2021 Category: Universities & Medical Training Source Type: news

Scientists develop brain organoids with complex neural activity
Researchers at the  Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA have developed brain organoids — 3D brain-like structures grown from human stem cells — that show organized waves of activity similar to those found in living human brains.Then, while studying organoids grown from stem cells derived from patients with the neurological disorder Rett syndrome, the scientists were able to observe patterns of electrical activity resembling seizures, a hallmark of the condition.The study, published today in the journal Nature Neuroscience, broadens the list of brain...
Source: UCLA Newsroom: Health Sciences - August 23, 2021 Category: Universities & Medical Training Source Type: news

Vaping just once raises oxidative stress levels in nonsmokers, increasing disease risk
The risk that both tobacco and electronic cigarettes can pose to regular smokers ’ health has been well documented, but a new UCLA study illustrates just how quickly vaping can affect the cells of even healthy younger nonsmokers.The findings,published today in JAMA Pediatrics, show that a single 30-minute vaping session can significantly increase cellular oxidative stress, which occurs when the body has  an imbalance between free radicals — molecules that can cause damage to cells — and antioxidants, which fight free radicals.“Over time,this imbalance can play a significant role in ca...
Source: UCLA Newsroom: Health Sciences - August 9, 2021 Category: Universities & Medical Training Source Type: news

New metric shows COVID cut average lifespan by nearly a decade in parts of U.S.
At its peak, COVID-19 drastically reduced the average human lifespan — by as much as 9 years in one U.S. state — according to a new longevity metric developed at UCLA.Sociology professor Patrick Heuveline devised the metric, called the mean unfulfilled lifespan, to assess the impact of temporary “shocks” like the novel coronavirus on average length of life. To date, the pandemic has claimed the lives of more than 4.2 million people worldwide.    The tool allows demographers to conduct fine-grained analyses in specific regions over various periods of time, offering a new and more dynam...
Source: UCLA Newsroom: Health Sciences - August 6, 2021 Category: Universities & Medical Training Source Type: news

UCLA establishes endowed chair in honor of longtime faculty member Dr. Marjorie Fine
Dr. Catherine Juillard, who studies ways to improve surgical care in underresourced countries, has been named UCLA ’s first Marjorie Fine, M.D., Professor of Clinical General Surgery.Juillard, an associate professor in residence in the UCLA Department of Surgery, is co-director of theProgram for the Advancement of Surgical Equity.“An endowed chair is one of the greatest honors a faculty member can receive,” Juillard said. “It is so much more meaningful to me and my colleagues that the chair also honors the career of a trailblazer, Dr. Marjorie Fine.”Juillard has been a member of the UCLA facul...
Source: UCLA Newsroom: Health Sciences - August 5, 2021 Category: Universities & Medical Training Source Type: news

UCLA creates the Academy for Excellence in Medical Education
The David Geffen School of Medicine at UCLA and the UCLA School of Education& Information Studies are joining to launch the Academy for Excellence in Medical Education — a multidisciplinary curriculum that promotes excellence through research, professional development, and school and community programs. In view of the two schools ’ shared values of social justice and service to community, this collaboration affords opportunities to further equity, inclusion and diversity in all areas of medical education. Core faculty members for the academy include; Amy Waterman, professor-in-residence in the med...
Source: UCLA Newsroom: Health Sciences - August 5, 2021 Category: Universities & Medical Training Source Type: news

New mothers ’ sleep loss linked to accelerated aging
When new mothers complain that all those sleepless nights caring for their newborns are taking years off their life, they just might be right, UCLA research published this summer in the journalSleep Healthsuggests.Scientists studied 33 mothers during their pregnancies and the first year of their babies ’ lives, analyzing the women’s DNA from blood samples to determine their “biological age,” which can differ from chronological age. They found that a year after giving birth, the biological age of mothers who slept less than seven hours a night at the six-month mark was three to seven years older than...
Source: UCLA Newsroom: Health Sciences - August 5, 2021 Category: Universities & Medical Training Source Type: news

Women voice frustration over current care for recurrent urinary tract infections
This study really gave us insight into the patient perspective and showed us those with recurrent UTIs are dissatisfied with the current management of the condition. Continued episodes can have a major impact on their quality of life.”More than half of women will develop a UTI at some point, and roughly 1 in 4 will have repeat infections that can last for years. Many with recurrent infections will be prescribed antibiotics frequently over their lifetime.The researchers conducted focus groups with 29 women with recurrent UTIs — defined as two infections in six months or three in a year. Participants were asked a...
Source: UCLA Newsroom: Health Sciences - August 4, 2021 Category: Universities & Medical Training Source Type: news

Nanotech device can detect risk for serious complication during pregnancy
Researchers from UCLA and Cedars-Sinai have developed a new way to detect a potentially life-threatening condition that can occur during pregnancy.The condition, placenta accreta spectrum disorder, occurs when the placenta grows too deeply into the uterine wall and fails to detach from the uterus after childbirth. It can lead to significant blood loss during pregnancy and delivery, requiring blood transfusions and intensive care, and it can result in serious illness and infection and can even be fatal for the mother. The condition occurs in less than 0.5% of pregnancies.Currently, placenta accreta spectrum disorder is diag...
Source: UCLA Newsroom: Health Sciences - August 3, 2021 Category: Universities & Medical Training Source Type: news

Text-message ‘nudges’ can encourage holdouts to get COVID vaccination, study finds
New UCLA-led research indicates that simple text messages emphasizing the easy availability of COVID-19 vaccines successfully boosted the number of people who got the shot.The researchers, from theDavid Geffen School of Medicine at UCLA, theUCLA Anderson School of Management and Carnegie Mellon University, say their findings held true across all demographics, including groups that have been hesitant to receive the vaccine.“We found that text messages that stressed the accessibility of the vaccine and that included ‘ownership’ language — such as ‘The vaccine has just been made available for you...
Source: UCLA Newsroom: Health Sciences - August 3, 2021 Category: Universities & Medical Training Source Type: news

Eliminating RNA-binding protein improves survival in aggressive leukemia
Removing a protein that is often overexpressed in a rare and aggressive subtype of leukemia can help to slow the cancer ’s development and significantly increase the likelihood of survival, according to a study in mice led by scientists at theUCLA Jonsson Comprehensive Cancer Center.The research,published today in the journal Leukemia, could aid in the development of targeted therapies for cancers that have high levels of the RNA-binding protein IGF2BP3 — especially acute lymphoblastic and myeloid leukemias that are characterized by chromosomal rearrangements in the mixed lineage leukemia (MLL) gene.In these ML...
Source: UCLA Newsroom: Health Sciences - July 29, 2021 Category: Universities & Medical Training Source Type: news

UCLA Health hospitals rank No. 1 in L.A. and state, No. 3 in nation
UCLA Health hospitals  are No. 1 in both Los Angeles and California and rose to No. 3 nationally in an annual evaluation published today by U.S. News& World Report. It is the first time UCLA Health has been ranked so highly nationally while also holding the top positions in both the city and the state.UCLA Health once again earned a coveted spot on thenational honor roll, which names only the 20 hospitals that provide the highest-quality care across a wide range of procedures and conditions.UCLA Health earnedtop 10 rankings in 12 specialties: diabetes and endocrinology (3), gastroenterology/gastrointestinal s...
Source: UCLA Newsroom: Health Sciences - July 27, 2021 Category: Universities & Medical Training Source Type: news

Research suggests ending eviction moratoriums led to spikes in COVID cases and deaths
Research by a UCLA-led team has determined that the number of COVID-19 cases and the   number of deaths from the disease both increased dramatically after states lifted eviction moratoriums that had been in place to protect people who were struggling to make rent payments during the pandemic.The study found that the number of COVID-19 cases doubled and the number of deaths attributable to the disease increased fivefold, in the four-month period after eviction moratoriums expired.Those figures suggest that during the summer of 2020, there were 433,700 more COVID-19 cases and 10,700 more deaths in the U.S. than there wo...
Source: UCLA Newsroom: Health Sciences - July 26, 2021 Category: Universities & Medical Training Source Type: news

More than 1 in 5 Californians did not follow restrictions on group gatherings
More than 1 in 5 California adults said they “never” or only “sometimes” followed state guidelines restricting group gatherings during the COVID-19 pandemic.  That ’s among the early findings from the 2021 California Health Interview Survey, published by the UCLA Center for Health Policy Research.The  2021 CHIS COVID-19 Preliminary Estimates Dashboard uses survey data collected during March and April, including responses to questions about how frequently people wore face coverings and washed their hands, and whether respondents practiced physical distancing or gathered with peop...
Source: UCLA Newsroom: Health Sciences - July 22, 2021 Category: Universities & Medical Training Source Type: news

Mental health needs might not be met among California ’s Latino and Asian communities
A pair of new UCLA studies suggest that mental health needs for some ethnic communities may be going unmet in part because people in those groups don ’t see themselves as needing care — despite the fact that they are reporting in surveys that they are experiencing symptoms of mental health distress.The studies, by theUCLA Center for Health Policy Research, are based on data from the center ’s ownCalifornia Health Interview Surveys from 2015 to 2019.As part of the surveys, researchers asked Californians whether they had experienced symptoms of depression, anxiety or other mental health challenges. Separate...
Source: UCLA Newsroom: Health Sciences - July 22, 2021 Category: Universities & Medical Training Source Type: news

Four UCLA research centers receive grants from California 100
In recognition of their expertise, UCLA researchers representing four research centers — spanning public health to urban planning to transportation — have been named recipients of financial awards from a new statewide initiative aimed at envisioning and shaping the long-term success of California.TheUCLA Center for Health Policy Research will use its award, along with technical assistance from the Institute for the Future, to evaluate current facts, origins and future trends health and wellness will play in California ’s next century. The center’s research will be led byNinez Ponce, director of the ...
Source: UCLA Newsroom: Health Sciences - July 19, 2021 Category: Universities & Medical Training Source Type: news

RNA modification may protect against liver disease, explain liver fat differences between sexes
FINDINGSA chemical modification that occurs in some RNA molecules as they carry genetic instructions from DNA to cells ’ protein-making machinery may offer protection against non-alcoholic fatty liver, a condition that results from a build-up of fat in the liver and can lead to advanced liver disease, according to a new study by UCLA researchers.The study, conducted in mice, also suggests that this modification — known as m6A, in which a methyl group attaches to an RNA chain — may occurat a different ratein femalesthan it does inmales, potentially explaining why females tend to have higher fat content in ...
Source: UCLA Newsroom: Health Sciences - July 19, 2021 Category: Universities & Medical Training Source Type: news

University of California to require all employees and students to get vaccinated against COVID-19
The University of California Office of the President issueda universitywide policy today requiring all UC students, trainees, personnel and all others who work, live and/or learn in any UC locations or otherwise participate in person in university programs to be fully vaccinated against COVID-19 at least 14 days prior to the first day of instruction for the fall term. This is subject to certain medical exemptions and accommodations based on disability or religious belief, and deferrals are available for those who are pregnant.This means UCLA faculty, staff and students working, living and/or learning on UCLA property will ...
Source: UCLA Newsroom: Health Sciences - July 16, 2021 Category: Universities & Medical Training Source Type: news

UCLA-led team awarded more than $5 million for HIV prevention projects
A team of researchers co-led byMatthew Mimiaga has received more than $5.2 million in grants from the National Institutes of Health to develop and test HIV interventions in the United States and Brazil.The projects, funded by three separate NIH grants, aim at reducing the spread of HIV, the virus that causes AIDS, through the use of antiretroviral medications for HIV primary, or PrEP, and secondary, or ART, prevention among sexual and gender minority groups.“Antiretroviral medications are highly effective at reducing HIV acquisition and transmission, but its efficacy is highly dependent on uptake and excellent adhere...
Source: UCLA Newsroom: Health Sciences - July 15, 2021 Category: Universities & Medical Training Source Type: news

Tool helps predict who will respond best to targeted prostate cancer therapy
A new prognostic tool developed by researchers from theUCLA Jonsson Comprehensive Cancer Center and five other institutionshelps predict which men with advanced metastatic prostate cancer will respond favorably to a novel targeted therapy.The tool,described in a study published today in Lancet Oncology, analyzesa wide spectrum of imaging and clinical data and is intended to assist physicians considering treating patients with Lutetium-177 prostate-specific membrane antigen, or LuPSMA.LuPSMA, which binds to PSMA proteins and delivers targeted radiation to prostate cancer tissue, offers a new option to men with PSMA-positive...
Source: UCLA Newsroom: Health Sciences - July 12, 2021 Category: Universities & Medical Training Source Type: news

Tool helps predicts who will respond best to targeted prostate cancer therapy
A new prognostic tool developed by researchers from theUCLA Jonsson Comprehensive Cancer Center and five other institutionshelps predict which men with advanced metastatic prostate cancer will respond favorably to a novel targeted therapy.The tool,described in a study published today in Lancet Oncology, analyzesa wide spectrum of imaging and clinical data and is intended to assist physicians considering treating patients with Lutetium-177 prostate-specific membrane antigen, or LuPSMA.LuPSMA, which binds to PSMA proteins and delivers targeted radiation to prostate cancer tissue, offers a new option to men with PSMA-positive...
Source: UCLA Newsroom: Health Sciences - July 9, 2021 Category: Universities & Medical Training Source Type: news

Thomas Rando named director of UCLA Broad Stem Cell Research Center
Dr. Thomas Rando, a renowned neurologist and stem cell biologist, has been named director of the  Eli and Edythe Broad Center of  Regenerative Medicine and Stem Cell Research at UCLA.Rando, who was chosen after an international search, is currently a professor of neurology and neurological sciences at the medical school at Stanford University, where he also serves as director of the Glenn Center for the Biology of Aging and deputy director of the Stanford Center on Longevity. In addition, he is chief of neurology at the  Veterans Affairs Palo Alto Health Care System.His appointment is effective Oct. 1.&ldquo...
Source: UCLA Newsroom: Health Sciences - July 7, 2021 Category: Universities & Medical Training Source Type: news

UCLA team awarded almost $3 million for safe K-12 return-to-school effort
A team of researchers co-led by UCLA professors  Moira Inkelas andDr. Mitch Wong has received almost $3 million in grants from the U.S. National Institutes of Health to use evidence-based research to inform policy makers of the safest ways to return to schools in vulnerable and underserved communities.UCLA ’s is one of is one of 15 teams that have received an award through institute’s initiative to help underserved populations safely return to schools through rapid diagnostic testing, NIH officials said.“The goal of our research is to reduce disparities in returning to in-person learning for tho...
Source: UCLA Newsroom: Health Sciences - July 7, 2021 Category: Universities & Medical Training Source Type: news

Women who vape are more likely to have low-birthweight babies, study shows
Women who use electronic cigarettes during pregnancy are 33% more likely than those who don ’t to give birth to low-birthweight infants, according to a new study by a team of researchers from UCLA and other institutions.Low-birthweight babies — those weighing less than 5.5 pounds — often require specialized medical care and are at greater risk of early-life complications and long-lasting health issues, saidAnnette Regan,the study ’s corresponding authorand an adjunct assistant professor of epidemiology at theUCLA Fielding School of Public Health.Findings from the study, which also involved researche...
Source: UCLA Newsroom: Health Sciences - July 7, 2021 Category: Universities & Medical Training Source Type: news

Conservatives ’ sensitivity to pandemic threat suppressed by distrust of science, media
Researchers studying the intersection of politics and psychology have long documented a link between threat sensitivity and social conservatism: People who are more socially conservative tend to react more strongly to threats. Conversely, those who are more socially liberal tend to be less sensitive to threats, viewing the world as a generally safe place and embracing change to explore new possibilities.These findings have held across a variety of events, but during the pandemic, U.S. polls show that Democrats, who tend to be more liberal, have generally been more concerned about the COVID-19 threat than Republicans, who t...
Source: UCLA Newsroom: Health Sciences - June 30, 2021 Category: Universities & Medical Training Source Type: news

In memoriam: Dr. Gerald S. Levey, 84, oversaw building of Ronald Reagan UCLA Medical Center
Dr. Gerald Levey, who led the transformation of UCLA ’s hospitals and medical school into a world-class academic health system, died at home of Parkinson’s disease on June 25. He was 84. Levey served the campus as vice chancellor of medical sciences and dean of the David Geffen School of Medicine at UCLA from 1994 to 2010. During his tenure, Levey amassed an extraordinarily long list of achievements, crowned by the construction of the Ronald Reagan UCLA Medical Center and the sealing of a $200 million gift to the UCLA School of Medicine by entertainment executive David Geffen.  “It&rsq...
Source: UCLA Newsroom: Health Sciences - June 30, 2021 Category: Universities & Medical Training Source Type: news

Differences in human, mouse brain cells have important implications for disease research
FINDINGSA UCLA-led study comparing brain cells known as astrocytes in humans and mice found that mouse astrocytes are more resilient to oxidative stress, a damaging imbalance that is a mechanism behind many neurological disorders. A lack of oxygen triggers molecular repair mechanisms in these mouse astrocytes but not in human astrocytes. In contrast, inflammation activates immune-response genes in human astrocytes but not mouse astrocytes.BACKGROUNDAlthough the mouse is a ubiquitous laboratory model used in research for neurological diseases, results from studies in mice are not always applicable to humans. In fact, more t...
Source: UCLA Newsroom: Health Sciences - June 25, 2021 Category: Universities & Medical Training Source Type: news

UCLA study reveals how immune cells can be trained to fight infections
This study shows how collaborations between researchers in the UCLA College and David Geffen School of Medicine can produce innovative and impactful science that benefits human health,” Hoffmann said.The study ’s co-lead author is Sho Ohta, an assistant professor at the University of Tokyo and a former postdoctoral scholar in Hoffmann’s UCLA laboratory. Other co-authors are UCLA M.D.–Ph.D. student Katherine Sheu; Roberto Spreafico, a former postdoctoral scholar in Hoffmann’s laboratory; Adewunmi A delaja, who earned his Ph.D. in Hoffmann’s laboratory and is now working toward his M.D. at...
Source: UCLA Newsroom: Health Sciences - June 24, 2021 Category: Universities & Medical Training Source Type: news

People who have had COVID-19 may require only single dose of two-dose vaccines
People who have previously been infected with COVID-19 may need only one dose of the two-dose mRNA vaccines to achieve maximum protection against the virus, a new UCLA study suggests. But all vaccinated individuals, whether previously infected or not, will likely require booster shots moving forward because antibodies created through both vaccines and natural infection wane at the same relatively rapid rate, the authors say.In astudy published today in the peer-reviewed journal ACS Nano, the researchers report that a previous COVID-19 infection effectively serves as the first “dose” of a two-dose vaccine, with ...
Source: UCLA Newsroom: Health Sciences - June 24, 2021 Category: Universities & Medical Training Source Type: news

Report identifies barriers to accessing dental care for low-income Californians
Apolicy brief by the UCLA Center for Health Policy Research identifies three of the most important factors that have led to disparities in Californians ’ access to dental care. There are fewer dentists per capita in some parts of the state.About 79% of the state ’s dentists did not provide care for low-income patients who rely on Medi-Cal.Only 8% of the state ’s dentists are Latino or Black, compared with 60% of the state’s low-income adult population overall.The authors also note that a shortage of dentists is looming: Some 23% of dentists are 60 years old or older and nearing retirement age, ...
Source: UCLA Newsroom: Health Sciences - June 21, 2021 Category: Universities & Medical Training Source Type: news

Medication may help heavy-drinking smokers improve their health
This study confirms that medications can play a role, Ray said, but she noted that it can be challenging for patients to take more than one prescribed medication.“Varenicline alone is doing a great job, and this trial indicates that there is not much room for naltrexone to make a difference,” Ray said. “But even medications like varenicline have their limitations. Medication is only part of the solution. There remains much research to be done on addict ions and how to treat them.”Ray says that those who wish to quit smoking and reduce drinking may consider talking to their doctor about the possibili...
Source: UCLA Newsroom: Health Sciences - June 15, 2021 Category: Universities & Medical Training Source Type: news

‘You clipped your wings to let us fly’
When Gabriela  López underwent open-heart surgery at age 12, no one prepared her for the agonizing pain she would suffer afterward. Once she awoke from anesthesia, she was terrified to see a thick tube protruding from her chest and to feel staples under her skin.None of her surgeons had explained the procedure in Spanish to her parents, who had immigrated from Mexico City. L ópez, who was born in the U.S., often served as her parents’ translator.That experience propelled L ópez, now 31, to pursue a career in medicine. The new graduate of the David Geffen School of Medicine at UCLA ...
Source: UCLA Newsroom: Health Sciences - June 10, 2021 Category: Universities & Medical Training Source Type: news

Drug commonly used as antidepressant helps fight cancer in mice
A class of drug called monoamine oxidase inhibitors is commonly prescribed to treat depression; the medications work by boosting levels of serotonin, the brain ’s “happiness hormone.”A new study by UCLA researchers suggests that those drugs, commonly known as MAOIs, might have another health benefit: helping the immune system attack cancer. Their findings are reported in two papers, which are published in the journals Science Immunology and Nature Communications.“MAOIs had not been linked to the immune system’s response to cancer before,” saidLili Yang, senior author of the study and a m...
Source: UCLA Newsroom: Health Sciences - June 10, 2021 Category: Universities & Medical Training Source Type: news

Research aims for best ways to treat COVID-19 at home
While more than 125 million Americans have received full doses of the COVID-19 vaccine, thousands of people in the U.S. are being diagnosed each day with the disease. Reports of severe illnesses, hospitalizations and deaths continue, more than a year after the pandemic began.While researchers around the world have properly prioritized vaccine development and life-saving treatments, less attention has been paid to the experiences of people with COVID-19 who are not hospitalized.Of the 33 million Americans who have tested positive for COVID-19, the vast majority have been instructed to quarantine and recover at home. And hal...
Source: UCLA Newsroom: Health Sciences - May 27, 2021 Category: Universities & Medical Training Source Type: news

Overdose deaths up 42% in 2020; largest increases among Black and Latino communities
FINDINGSBased on cases handled by emergency medical services, the number of people in the U.S. who died due to drug overdoses was 42% higher in 2020 than the average number of overdose deaths in 2018 and 2019.According to a study by researchers from UCLA, Northeastern University and the University of Utah, the largest increases were among Black Americans (50.3%) and Latinos (49.7%). Spikes were also most pronounced in low-income neighborhoods (46.4%) and in the five states — Alaska, California, Hawaii, Oregon and Washington — that border the Pacific Ocean (63.8%).BACKGROUNDPublic health authorities had expected...
Source: UCLA Newsroom: Health Sciences - May 27, 2021 Category: Universities & Medical Training Source Type: news

UCLA analysis reveals need to break down COVID-19 data for ethnic subgroups
According toa new UCLA report, COVID-19 case rates and death rates for Californians from Native Hawaiian, Pacific Islander and Asian ethnic groups varied widely in 2020.But those variations were not readily apparent to the public because federal and state reports generally present COVID-19 data for all of those groups as a whole, rather than for each of the subgroups individually.The study, by theUCLA Center for Health Policy Research, suggests that breaking out the data for each of the racial and ethnic groups analyzed by the authors wouldenable public health officials and policymakers to identify the hardest-hit communit...
Source: UCLA Newsroom: Health Sciences - May 26, 2021 Category: Universities & Medical Training Source Type: news