A dive into the genetic history of India, and the role of vitamin A in skin repair
What modern Indian genomes say about the region’s deep past, and how vitamin A influences stem cell plasticityFirst up this week, Online News Editor Michael Price and host Sarah Crespi talk about a large genome sequencing project in India that reveals past migrations in the region and a unique intermixing with Neanderthals in ancient times. Next on the show, producer Kevin McLean chats with Matthew Tierney, a postdoctoral fellow at Rockefeller University, about how vitamin A and stem cells work together to grow hair and heal wounds. This week’s episode was produced with help from Podigy. About the Science Podcast A...
Source: Science Magazine Podcast - March 7, 2024 Category: Science Authors: Science Magazine Source Type: podcasts
Radioimmunotherapy Tops ASCT in R/R Follicular Lymphoma
A new trial from Italy challenges a decades-old assumption that autologous stem cell transplant is more effective than radioimmunotherapy for consolidation after follicular lymphoma relapse. (Source: Medscape Transplantation Podcast)
Source: Medscape Transplantation Podcast - December 5, 2023 Category: Transplant Surgery Authors: Medscape 210869 Source Type: podcasts
Why does cancer spread to the spine? Newly discovered stem cells might be the key
In this episode:00:45 A new insight into cancers' selective spreadCancer cells can spread to bones in the late stages of disease and in many cancers, cells actually preferentially metastasise to the spine. The reason for this has been a puzzle to researchers for years, but now a team has found a new kind of stem cell that may be involved in this process. The stem cell is found in mice and humans and could represent a clinical target in the treatment of cancer.Research article: Sun et al.News and Views: Stem cells provide clues to why vertebrae attract tumour cells09:55 Research HighlightsA preference for certain percussion...
Source: Nature Podcast - September 20, 2023 Category: Science Authors: Springer Nature Limited Source Type: podcasts
How the Australian wildfires devastated the ozone layer
00:47 Wildfire smoke’s chemical composition enhances ozone depletionSmoke from the devastating Australian wildfires of 2019-2020 led to a reduction in ozone levels in the upper atmosphere, but it’s been unclear how. Now, a team proposes that smoke’s particulate matter can enhance the production of ozone depleting chemicals, matching satellite observations during the Australian fires. The results spark concerns that future wildfires, which are set to grow more frequent with ongoing climate change, will undo much of the progress towards restoration of the ozone layer.Research article: Solomon et al.News & Views: Ho...
Source: Nature Podcast - March 8, 2023 Category: Science Authors: Springer Nature Limited Source Type: podcasts
Human brain organoids implanted into rats could offer new way to model disease
In this episode:00:45 Implanted brain organoids could offer new insights into diseaseBrain organoids — lab-grown, self-organizing structures made of stem cells — are used in research to better understand brain development and disease progression. However, these structures lack connections seen in real brains, limiting their usefulness. To overcome this, a team has now transplanted human organoids into the brains of newborn rats, showing that these implanted organoids respond to stimuli and could influence the animals’ behaviour.Research article: Revah et al.News and Views: Human brain organoids influence rat behaviou...
Source: Nature Podcast - October 12, 2022 Category: Science Authors: Springer Nature Limited Source Type: podcasts
TWiV 829: Antiviral and cytotoxically empowered for COVID-19
A TWiV duo reviews how SARS-CoV-2 attacks the olfactory mucosa but spares the olfactory bulb, vaccination with BNT162b2 induces virus-specific stem cell memory T cells, and development of an oral protease inhibitor for the treatment of COVID-19. Hosts: Vincent Racaniello and Brianne Barker Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode How SARS-CoV-2 attacks olfactory mucosa (Cell) SARS-CoV-2-specific stem cell memory T cells after mRNA vaccine (Sci Immunol) Oral SARS-CoV-2 protease inhibitor (Science) Paxlovid phase 2/3 trial preliminary results (Pfizer) Lette...
Source: This Week in Virology - MP3 Edition - November 14, 2021 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
New hope for vaccine against a devastating livestock disease
A vaccine candidate for a neglected tropical disease, and calls to extend the 14-day limit on embryo research.In this episode:00:46 A vaccine candidate for an important livestock diseaseAfrican animal trypanosomiasis is a parasitic disease that kills millions of cattle each year, affecting livelihoods and causing significant economic costs in many sub-Saharan countries. Developing a vaccine against the disease has proved difficult as the parasite has a wealth of tricks to evade the immune system. This week however, a team of researchers have created a vaccine candidate that shows early promise in mice.Research Arti...
Source: Nature Podcast - May 26, 2021 Category: Science Authors: Springer Nature Limited Source Type: podcasts
New hope for vaccine against a devastating livestock disease
A vaccine candidate for a neglected tropical disease, and calls to extend the 14-day limit on embryo research.In this episode:00:46 A vaccine candidate for an important livestock diseaseAfrican animal trypanosomiasis is a parasitic disease that kills millions of cattle each year, affecting livelihoods and causing significant economic costs in many sub-Saharan countries. Developing a vaccine against the disease has proved difficult as the parasite has a wealth of tricks to evade the immune system. This week however, a team of researchers have created a vaccine candidate that shows early promise in mice.Research Arti...
Source: Nature Podcast - May 26, 2021 Category: Science Authors: Springer Nature Limited Source Type: podcasts
The quark of the matter: what's really inside a proton?
The surprising structure of protons, and a method for growing small intestines for transplantation.In this episode:00:45 Probing the proton’s interiorAlthough studied for decades, the internal structure of the proton is still throwing up surprises for physicists. This week, a team of researchers report an unexpected imbalance in the antimatter particles that make up the proton.Research Article: Dove et al.News and Views: Antimatter in the proton is more down than up07:08 Research HighlightsHow an inactive gene may help keep off the chill, and Cuba’s isolation may have prevented invasive species taking root on the islan...
Source: Nature Podcast - February 24, 2021 Category: Science Authors: Springer Nature Limited Source Type: podcasts
The quark of the matter: what's really inside a proton?
The surprising structure of protons, and a method for growing small intestines for transplantation.In this episode:00:45 Probing the proton’s interiorAlthough studied for decades, the internal structure of the proton is still throwing up surprises for physicists. This week, a team of researchers report an unexpected imbalance in the antimatter particles that make up the proton.Research Article: Dove et al.News and Views: Antimatter in the proton is more down than up07:08 Research HighlightsHow an inactive gene may help keep off the chill, and Cuba’s isolation may have prevented invasive species taking root on the islan...
Source: Nature Podcast - February 24, 2021 Category: Science Authors: Springer Nature Limited Source Type: podcasts
Lab –grown brains and the debate over consciousness
The chances of mini-brains becoming sentient, and a UK government decision threatens gender diversity in academia.In this episode:00:59 The ethics of creating consciousnessBrain organoids, created by culturing stem cells in a petri dish, are a mainstay of neuroscience research. But as these mini-brains become more complex, is there the chance they could become conscious, and if so, how could we tell?News Feature: Can lab-grown brains become conscious?09:01 CoronapodSo called ‘herd immunity’ is claimed by some as a way to break the chain of infection and curtail the pandemic. However epidemiologists say that this course...
Source: Nature Podcast - October 28, 2020 Category: Science Authors: Springer Nature Limited Source Type: podcasts
Why skin grows bigger as you stretch it
Skin's unusual response to stretching is finally explained, and the latest in a huge effort to map DNA.In this episode:01:06 Stretching skinFor decades it’s been known that stretching skin causes more skin to grow, but the reasons why have been a mystery. Now, researchers have uncovered a mechanism to explain the phenomenon. Research Article: Aragona et al.; News and Views: Stretch exercises for stem cells expand the skin07:49 CoronapodWe discuss how the coronavirus pandemic has affected scientific meetings and how the learned societies that organise them are adapting. How scientific conferences will survive the cor...
Source: Nature Podcast - July 29, 2020 Category: Science Authors: Springer Nature Limited Source Type: podcasts
ASFH Adipose-Derived Stem Cells for Keratoconus
Guest: Jorge L. Alió, M.D., Ph.D. Professor and Chairman Instituto Oftalmologico de Alicante Universidad Miguel Hernandez Alicante, Spain (Source: As Seen From Here)
Source: As Seen From Here - November 3, 2019 Category: Opthalmology Authors: JYoungMD at gmail.com Source Type: podcasts
