Next-Level Adeno-Associated Virus (AAV) Production 
Take the leap from shake flasks to bioreactors. (Source: The Scientist)
Source: The Scientist - January 2, 2024 Category: Science Tags: The Marketplace Source Type: news

What Causes Conjunctivitis? A Panoply of Pathogens, Study Shows
(MedPage Today) -- Pathogens associated with acute infectious conjunctivitis varied among regions, a cross-sectional study showed. Among 52 patients from four sites in the U.S. and one in Israel, RNA deep sequencing found human adenovirus species... (Source: MedPage Today Pediatrics)
Source: MedPage Today Pediatrics - November 3, 2023 Category: Pediatrics Source Type: news

Africa: Why Some People Got Blood Clots After the Astrazeneca Vaccine - New Clues
[The Conversation Africa] AstraZeneca in partnership with the University of Oxford developed one of the first vaccines against COVID. The vaccine, which used an adenovirus to smuggle instructions into human cells to make antibodies against the novel coronavirus, saved countless lives. But a problem soon emerged. A tiny proportion - about one in 50,000 - of those vaccinated developed blood clots. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - October 31, 2023 Category: African Health Tags: Africa Coronavirus Health and Medicine Source Type: news

How Many Diphtheria Vaccines are Currently Licensed in the US?
Discussion Diphtheria is caused by the toxin produced by Corynebacterium diphtheriae. Two other Corynebacterium species (C. ulcerans and C. pseudotuberculosis) may produce diphtheria toxin; both species are zoonotic. Diphtheria is spread by respiratory droplets and also contact with open ulcers or sores. Incubation period is 1-10 days with a usual period of 2-5 days. The bacteria attacks the respiratory tract mucosa causing cellular death which in turn causes a “pseudomembrane” of tissue to build up causing respiratory distress and possible death due to airway obstruction (5-10% for general population but up to...
Source: - September 25, 2023 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

Gene Therapy Promising for Rare Jaundice Syndrome
(MedPage Today) -- Gene therapy for Crigler-Najjar syndrome appeared promising in patients treated at a higher dose, a phase I/II trial showed. A single infusion of GNT0003 -- an adeno-associated virus serotype 8 vector carrying a correction... (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - August 17, 2023 Category: Gastroenterology Source Type: news

Adenovirus May Trigger Thrombocytopenia, Thrombosis, Case Studies Suggest
(MedPage Today) -- In rare cases, symptomatic human adenovirus infection may trigger a life-threatening prothrombotic anti-platelet factor 4 (PF4) disorder resembling vaccine-induced immune thrombotic thrombocytopenia (VITT), according to a report... (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - August 9, 2023 Category: Cardiology Source Type: news

Monthly News Roundup - June 2023
Elevidys is First Gene Therapy Cleared to Treat Duchenne Muscular Dystrophy  In June, the FDA granted accelerated approval of Elevidys (delandistrogene moxeparvovec-rokl) from Sarepta Therapeutics, Inc. Elevidys is an adeno-associated virus... (Source: - Pharma News)
Source: - Pharma News - June 30, 2023 Category: Pharmaceuticals Source Type: news

Controversial Gene Therapy Wins FDA Approval for Duchenne Muscular Dystrophy
(MedPage Today) -- The FDA granted accelerated approval to delandistrogene moxeparvovec (Elevidys), the first gene therapy for Duchenne muscular dystrophy, the agency announced Thursday. The adeno-associated virus-based gene therapy is a one-time... (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - June 22, 2023 Category: Neurology Source Type: news

Children are catching flu more often now: Medical experts
A lot of children under the age of 15 are getting infected with adenovirus and Covid-19, with some cases leading to complications like pneumonia, doctors said. (Source: The Economic Times)
Source: The Economic Times - April 12, 2023 Category: Consumer Health News Source Type: news

What Causes Parotitis?
Discussion The salivary glands are important for creating saliva which helps with taste, digestion, oral health, and speech. Salivary gland problems are not that common but can be painful, annoying or herald potential systemic diseases. The parotid gland is the largest salivary gland lying anterior to the ear within the cheek structures. There are 2 lobes (superficial and deep) and the facial nerve runs between them. The salivary duct opens adjacent to the upper second molar. Infections are the most common cause of parotitis with mumps being the most commonly associated infection especially in unimmunized patients. Patient...
Source: - April 10, 2023 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

U.S. Study Backs 'Helper' Virus Theory in Kids' Mystery Hepatitis Cases
(MedPage Today) -- Genotyping results from blood samples of U.S. children with severe acute hepatitis of unknown cause support prior research suggesting that adeno-associated virus 2 (AAV2) along with a "helper" virus may be to blame for last year... (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - March 31, 2023 Category: Gastroenterology Source Type: news

Mysterious hepatitis outbreak in kids in 2022 linked to common childhood respiratory virus, studies suggest
An outbreak of acute severe, unexplained hepatitis in previously healthy children in 2022 may be linked to adeno-associated virus 2, or AAV2, according to three independent studies published Thursday in the journal Nature. (Source: - Health)
Source: - Health - March 31, 2023 Category: Consumer Health News Source Type: news

Sick With Something That Isn ’ t COVID-19 or the Flu? Here ’ s What It Might Be
Flu season is wrapping up, and weekly COVID-19 diagnoses are declining. But if you’re currently sick with a respiratory illness, you’re not alone. Data from the U.S. Centers for Disease Control and Prevention (CDC) show that a mixture of respiratory viruses are circulating right now, including common coronaviruses (other than SARS-CoV-2, which causes COVID-19), respiratory adenovirus, and parainfluenza (which is distinct from influenza). All of these viruses can cause cold-like symptoms including fever, runny nose, sore throat, and cough, so “it’s very, very hard to tell the difference between any o...
Source: TIME: Health - March 20, 2023 Category: Consumer Health News Authors: Jamie Ducharme Tags: Uncategorized Disease healthscienceclimate Source Type: news

Virus outbreak in West Bengal leaves 19 children dead and thousands in hospital
Indian state in crisis after adenovirus hits 12,000 people this year and families with sick children camp outside Kolkata hospitalNineteen children have died of acute respiratory infections in West Bengal this year, and thousands more are in hospital as India grapples with an adenovirus outbreak.More than 12,000 cases of adenovirus have been recorded in the state since January. More than 3,000 children have been admitted to hospital with severe flu-like symptoms.Continue reading... (Source: Guardian Unlimited Science)
Source: Guardian Unlimited Science - March 15, 2023 Category: Science Authors: Puja Bhattacharjee in Kolkata Tags: Global health Global development India South and central Asia World news Infectious diseases Microbiology Science Source Type: news