Combo of virotherapy and radiotherapy shows early promise in patients with esophageal cancer
(American Association for Cancer Research) The experimental oncolytic adenovirus telomelysin (OBP-301) in combination with radiotherapy was safe and showed early clinical efficacy in vulnerable patients with esophageal cancer, according to results from a phase I clinical trial presented at the AACR Annual Meeting 2019, March 29-April 3. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - April 2, 2019 Category: Cancer & Oncology Source Type: news

How Long Does Fecal Shedding Occur for Oral Vaccines?
Discussion Vaccination has reduced infectious disease morbidity and mortality since its introduction. Vaccines can be given intramuscularly, subcutaneously or orally. Oral virus vaccines currently used in the US include rotavirus, cholera, typhoid and adenovirus. Adenovirus vaccine is used in military personnel. As these are attenuated viruses there is concern for household contacts who are immunocompromised who may inadvertently be exposed to the virus through fecal shedding. Additionally, there is a concern that the attenuated virus may mutate and revert back to its wild-form and potentially cause disease. Injectable po...
Source: PediatricEducation.org - March 25, 2019 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

Federal Investigators Find Critical Failings at Health Center Where 11 Children Died in Virus Outbreak
A viral outbreak killed 11 children at a New Jersey health center last year due to a lack of administrative oversight, slow responses from medical staff and a flawed infection-control plan, according to a federal investigation. Wanaque Center for Nursing and Rehabilitation in Haskell, N.J. is strongly contesting investigators’ findings. The 114-page report, which was compiled by the New York regional office of the Centers for Medicare and Medicaid Services (CMS) and reviewed by TIME, says the pediatric medical director at the Wanaque Center “didn’t understand what medical director meant” when he ass...
Source: TIME: Health - March 4, 2019 Category: Consumer Health News Authors: Jamie Ducharme Tags: Uncategorized healthytime Infectious Disease New Jersey onetime Source Type: news

What Is the Most Common Type of Cardiomyopathy?
Discussion Barth syndrome is characterized by a dilated cardiomyopathy, proximal skeletal muscle weakness, neutropenia and short stature that usually presents at birth or soon after. It is a rare X-linked recessive disease process caused by mutations in the TAZ gene. The TAZ gene codes for tafazzin which alters cardiolipin in mitochondria. Characteristic facies can be seen especially in infancy including a tall and broad forehead, prominent chin and full cheeks, larger ears, and deep-set eyes. Most patients present at birth or soon afterwards but some may not until later in life. Life expectancy is reduced with many childr...
Source: PediatricEducation.org - February 25, 2019 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

Enterovirus associated with risk of coeliac disease
Early childhood infection with enterovirus – but not adenovirus – linked to later coeliac disease Related items fromOnMedica Probiotics in newborns might lower diabetes risk Women less likely than men to achieve CHD targets Send children with suspected diabetes to hospital immediately, GPs urged Scans show severe brain damage in Zika-affected babies Many overweight teens don ’t realise they’re too heavy (Source: OnMedica Latest News)
Source: OnMedica Latest News - February 14, 2019 Category: UK Health Source Type: news

CRISPR-mediated activation of a promoter or enhancer rescues obesity caused by haploinsufficiency
A wide range of human diseases result from haploinsufficiency, where the function of one of the two gene copies is lost. Here, we targeted the remaining functional copy of a haploinsufficient gene using CRISPR-mediated activation (CRISPRa) in Sim1 and Mc4r heterozygous mouse models to rescue their obesity phenotype. Transgenic-based CRISPRa targeting of the Sim1 promoter or its distant hypothalamic enhancer up-regulated its expression from the endogenous functional allele in a tissue-specific manner, rescuing the obesity phenotype in Sim1 heterozygous mice. To evaluate the therapeutic potential of CRISPRa, we injected CRIS...
Source: ScienceNOW - January 17, 2019 Category: Science Authors: Matharu, N., Rattanasopha, S., Tamura, S., Maliskova, L., Wang, Y., Bernard, A., Hardin, A., Eckalbar, W. L., Vaisse, C., Ahituv, N. Tags: Genetics, Medicine, Diseases, Online Only r-articles Source Type: news

University Of Maryland confirms 40 adenovirus cases
One student at the university has been hospitalized with the illness (Source: Health News: CBSNews.com)
Source: Health News: CBSNews.com - December 22, 2018 Category: Consumer Health News Source Type: news

Health Highlights: Dec. 6, 2018
Here are some of the latest health and medical news developments, compiled by the editors of HealthDay: Staff at N.J. Facility Where 11 Children Died Did Not Follow Sanitation Procedures The adenovirus outbreak that infected more than 30 children... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - December 6, 2018 Category: General Medicine Source Type: news

Adenovirus Kills 12 in 2 States, But What Is It?
Adenovirus refers to a cluster of viruses -- more than 50 known strains -- that most commonly infect the respiratory system. Each strain may bring about a different set of symptoms, such as the common cold, sore throat, fever, bronchitis, and pneumonia (Source: WebMD Health)
Source: WebMD Health - December 5, 2018 Category: Consumer Health News Source Type: news

Morning Break: CDC on Tick Watch; Toothpaste and Early Puberty; Adenovirus Mystery
(MedPage Today) -- Health news and commentary from around the Web gathered by the MedPage Today staff (Source: MedPage Today Psychiatry)
Source: MedPage Today Psychiatry - December 4, 2018 Category: Psychiatry Source Type: news

Family speaks out on Maryland student's adenovirus-related death
The parents of a University of Maryland student who died after contracting the adenovirus are speaking out about conditions on campus. Freshman Olivia Paregol died last week after complaining about flu-like symptoms. Jericka Duncan spoke to the parents about what they think contributed to her death. (Source: Health News: CBSNews.com)
Source: Health News: CBSNews.com - November 28, 2018 Category: Consumer Health News Source Type: news

Three more University of Maryland students sickened with adenovirus
Another three University of Maryland students have fallen ill with adenovirus. Now, a total of eight people there have been sickened, including one immunocompromised girl who died last week. (Source: the Mail online | Health)
Source: the Mail online | Health - November 27, 2018 Category: Consumer Health News Source Type: news

Parents of Maryland student who died say health center didn't test for adenovirus
Freshman Olivia Paregol's father also believes mold in her dorm room contributed to her death (Source: Health News: CBSNews.com)
Source: Health News: CBSNews.com - November 27, 2018 Category: Consumer Health News Source Type: news

Adenovirus death: Father says dorm mold "didn't help" ill daughter
The University of Maryland is trying to calm fears that recent mold problems on campus could be linked to a virus that caused a student's death. Freshman Olivia Paregol, 18, died on Sunday after contracting adenovirus, which typically causes respiratory illness. The university said five more students have illnesses tied to the virus, but insists there's "no consistent connection" to mold. Olivia's father believes the school could have done more. Jericka Duncan reports (Source: Health News: CBSNews.com)
Source: Health News: CBSNews.com - November 22, 2018 Category: Consumer Health News Source Type: news

Adenovirus death: Father says dorm mold "didn't help" ill daughter
As 5 more students confirmed to have illnesses tied to the virus, University of Maryland insists there's "no consistent connection" to mold problems (Source: Health News: CBSNews.com)
Source: Health News: CBSNews.com - November 22, 2018 Category: Consumer Health News Source Type: news

U of Maryland Student Dies of Adenovirus-Related Illness
WEDNESDAY, Nov. 21, 2018 -- An 18-year-old University of Maryland student has died from an adenovirus-related illness, and there have been reports of five other cases among students. Recently, at least 11 children at a New Jersey rehab facility died... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - November 21, 2018 Category: Pharmaceuticals Source Type: news

College student, 18, dies of adenovirus days before Thanksgiving
Olivia Paregol, an 18-year-old freshman at the University of Maryland died of adenovirus on Sunday after battling Crohn's disease and complications of the virus that has killed several New Jersey kids. (Source: the Mail online | Health)
Source: the Mail online | Health - November 21, 2018 Category: Consumer Health News Source Type: news

Maryland College Freshman Dies of Same Virus That Killed 11 Kids in N.J. Medical Facility
A University of Maryland freshman has died after contracting the same strain of adenovirus that killed 11 children in a New Jersey health clinic earlier this fall. The student, who was identified as 18-year-old Olivia Paregol by her father, died after contracting adenovirus 7, according to WJLA. The school confirmed in a statement that a student died of the virus, but declined to release her name. The virus is linked to symptoms such as respiratory problems or conjunctivitis, according to the CDC. “She definitely appeared to be getting sicker and sicker,” Ian Paregol, her father, told WJLA. “It is the wor...
Source: TIME: Health - November 21, 2018 Category: Consumer Health News Authors: Tara Law Tags: Uncategorized Maryland onetime public health Source Type: news

University of Maryland student dies from adenovirus-related illness
A student at the University of Maryland has died from adenovirus associated illness, the director of the university's health center said in a statement Tuesday. (Source: CNN.com - Health)
Source: CNN.com - Health - November 21, 2018 Category: Consumer Health News Source Type: news

Morning Break: Toss That Romaine; Genital Mutilation Legal; Fatal Adenovirus
(MedPage Today) -- Health news and commentary from around the Web gathered by the MedPage Today staff (Source: MedPage Today Public Health)
Source: MedPage Today Public Health - November 21, 2018 Category: American Health Source Type: news

University of Maryland student dies from adenovirus related illness
A student at the University of Maryland has died from adenovirus associated illness, the director of the university's health center said in a statement Tuesday. (Source: CNN.com - Health)
Source: CNN.com - Health - November 21, 2018 Category: Consumer Health News Source Type: news

WATCH: Maryland college student dies of adenovirus
Olivia Paregol, 18, a freshman at the University of Maryland, died of adenovirus on Sunday, Nov. 18, 2018. Her father says the school should've warned students sooner. (Source: ABC News: Health)
Source: ABC News: Health - November 21, 2018 Category: Consumer Health News Tags: Health Source Type: news

11th Child Dies in Adenovirus Outbreak at N.J. Care Facility
MONDAY, Nov. 19, 2018 -- An 11th child has died in an outbreak of a respiratory virus at the Wanaque Center for Nursing and Rehabilitation in New Jersey, health officials say. The " severely ill child " had the adenovirus infection and died Thursday... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - November 19, 2018 Category: Pharmaceuticals Source Type: news

11th child dies in adenovirus outbreak in New Jersey
An 11th child has died and 23 additional children have become sick in connection with an adenovirus outbreak at a New Jersey health care facility, the state's Department of Health announced Friday. (Source: CNN.com - Health)
Source: CNN.com - Health - November 16, 2018 Category: Consumer Health News Source Type: news

11th child dies in viral outbreak at N.J. facility
The state health department confirmed that the "severely ill child" at the Wanaque Center for Nursing and Rehabilitation had the adenovirus infection ‚Äč (Source: Health News: CBSNews.com)
Source: Health News: CBSNews.com - November 16, 2018 Category: Consumer Health News Source Type: news

Kids killed by virus in NJ center 'were in critical stage DAYS before they got to ER'
10 kids have died and 23 have been sickened by the adenovirus - which infects the linings of the eyes, lungs and nerves - at the Wanaque Center for Nursing and Rehab in the small town of Haskell. (Source: the Mail online | Health)
Source: the Mail online | Health - November 15, 2018 Category: Consumer Health News Source Type: news

Mother sues facility after 10 children died in adenovirus outbreak
After her 15-year-old son ended up "in critical and life-threatening condition" from an adenovirus outbreak at a New Jersey health care facility, one mother is suing those who she believes allowed her son to end up in the ICU, according to a lawsuit filed Wednesday. (Source: CNN.com - Health)
Source: CNN.com - Health - November 10, 2018 Category: Consumer Health News Source Type: news

More children sickened in New Jersey adenovirus outbreak: 30 now ill
A particularly strong strain of adenovirus has struck 30 children in New Jersey care facilities, killing 10, the state's Health Department said this week. A warm, wet fall may drive up cases this season. (Source: the Mail online | Health)
Source: the Mail online | Health - November 7, 2018 Category: Consumer Health News Source Type: news

30 now ill, including 10 deaths, in adenovirus outbreak
A total of 30 have become sick, including 10 deaths, in connection with an adenovirus outbreak at a New Jersey health care facility, the state's Department of Health announced Monday. (Source: CNN.com - Health)
Source: CNN.com - Health - November 7, 2018 Category: Consumer Health News Source Type: news

30 now ill, including 10 deaths, in adenovirus outbreak in New Jersey
A total of 30 have become sick, including 10 deaths, in connection with an adenovirus outbreak at a New Jersey health care facility, the state's Department of Health announced Monday. (Source: CNN.com - Health)
Source: CNN.com - Health - November 6, 2018 Category: Consumer Health News Source Type: news

Parents of girl, 4, who died of adenovirus in New Jersey facility say daughter was 'neglected'
The parents of four-year-old Doracase Dolcin said that when they visited her at the Wanaque Center, she was often sitting in a dirty diaper and that staff didn't even give her a flu shot. (Source: the Mail online | Health)
Source: the Mail online | Health - November 5, 2018 Category: Consumer Health News Source Type: news

Tenth Child Dies From Viral Outbreak at New Jersey Facility Tenth Child Dies From Viral Outbreak at New Jersey Facility
A 10th child has died in a viral outbreak at a rehabilitation center in northern New Jersey, where 27 young patients with compromised immune systems have been confirmed with adenovirus infections, state health officials said.Reuters Health Information (Source: Medscape Pediatrics Headlines)
Source: Medscape Pediatrics Headlines - November 3, 2018 Category: Pediatrics Tags: Pediatrics News Source Type: news

Adenovirus 2018 outbreak: What is KILLER virus spreading in New Jersey children?
ADENOVIRUS has broken out in a New Jersey hospital, where children are being killed by the deadly disease. What is Adenovirus and how is it spread? (Source: Daily Express - Health)
Source: Daily Express - Health - November 2, 2018 Category: Consumer Health News Source Type: news

New Jersey Adenovirus Outbreak Claims 10th Child
Adenovirus occur on on unclean surfaces and medical instruments, and common disinfectants may not remove them, CNN reported. (Source: WebMD Health)
Source: WebMD Health - November 1, 2018 Category: Consumer Health News Source Type: news

The Latest: Officials confirm new viral case amid outbreak
New Jersey health officials say they've confirmed a new case associated with an adenovirus outbreak at a pediatric rehabilitation center (Source: ABC News: Health)
Source: ABC News: Health - November 1, 2018 Category: Consumer Health News Tags: Health Source Type: news

10th Child Dies in Adenovirus Outbreak at N.J. Facility
THURSDAY, Nov. 1, 2018 -- A 10th child has died in an adenovirus outbreak at the Wanaque Center for Nursing and Rehabilitation in Haskell, N.J., according to the state health department. The health department said that at least 27 children at the... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - November 1, 2018 Category: Pharmaceuticals Source Type: news

New Jersey Adenovirus Outbreak Claims 10th Child
Adenovirus occur on on unclean surfaces and medical instruments, and common disinfectants may not remove them, CNN reported. (Source: WebMD Health)
Source: WebMD Health - November 1, 2018 Category: Consumer Health News Source Type: news

Former patient describes grim conditions at health center where 10 children died
Officials confirm 10th child has died in outbreak of adenovirus at a New Jersey medical facility (Source: Health News: CBSNews.com)
Source: Health News: CBSNews.com - November 1, 2018 Category: Consumer Health News Source Type: news

10th Patient Dies in Viral Outbreak at New Jersey Pediatric Facility
TRENTON, N.J. (AP) — Health officials say a 10th patient has died from an infection at a pediatric care facility in New Jersey as a different strain of the virus has been found at another facility in the state. The state health department on Wednesday confirmed the "medically fragile child" at the Wanaque Center for Nursing and Rehabilitation had the adenovirus infection. The department says 27 cases have been associated with the respiratory virus at the center. The affected children had severely compromised immune systems. One death was a young adult. Meanwhile, the state says there are four confirmed aden...
Source: JEMS Patient Care - November 1, 2018 Category: Emergency Medicine Tags: Patient Care News Source Type: news

10th Patient Dies in Viral Outbreak at New Jersey Pediatric Facility
TRENTON, N.J. (AP) — Health officials say a 10th patient has died from an infection at a pediatric care facility in New Jersey as a different strain of the virus has been found at another facility in the state. The state health department on Wednesday confirmed the "medically fragile child" at the Wanaque Center for Nursing and Rehabilitation had the adenovirus infection. The department says 27 cases have been associated with the respiratory virus at the center. The affected children had severely compromised immune systems. One death was a young adult. Meanwhile, the state says there are four confirmed aden...
Source: JEMS: Journal of Emergency Medical Services News - November 1, 2018 Category: Emergency Medicine Tags: Patient Care News Source Type: news

Infection-Control Teams Sent to New Jersey Pediatric Centers
TRENTON, N.J. (AP) — New Jersey health officials said Monday they are sending infection-control teams to four long-term pediatric centers and a hospital to assist with training amid viral and bacterial outbreaks that have left 10 people dead. The teams will assess infection prevention practices and deploy beginning in November, according to Health Commissioner Dr. Shereef Elnahal. The response comes amid a fatal adenovirus outbreak at the Wanaque Center for Nursing and Rehabilitation that left 9 people dead, most under age 18. In addition, a premature baby died following the discovery of a bacterial infection at Newa...
Source: JEMS Patient Care - November 1, 2018 Category: Emergency Medicine Tags: Patient Care News Source Type: news

Infection-Control Teams Sent to New Jersey Pediatric Centers
TRENTON, N.J. (AP) — New Jersey health officials said Monday they are sending infection-control teams to four long-term pediatric centers and a hospital to assist with training amid viral and bacterial outbreaks that have left 10 people dead. The teams will assess infection prevention practices and deploy beginning in November, according to Health Commissioner Dr. Shereef Elnahal. The response comes amid a fatal adenovirus outbreak at the Wanaque Center for Nursing and Rehabilitation that left 9 people dead, most under age 18. In addition, a premature baby died following the discovery of a bacterial infection at Newa...
Source: JEMS: Journal of Emergency Medical Services News - November 1, 2018 Category: Emergency Medicine Tags: Patient Care News Source Type: news

Another child dies of adenovirus at New Jersey pediatric center
The death on Wednesday came shortly after officials announced one more child had been sickened at the Wanaque Center for Nursing and Rehabilitation. (Source: the Mail online | Health)
Source: the Mail online | Health - November 1, 2018 Category: Consumer Health News Source Type: news

Tenth child dies from viral outbreak at New Jersey facility
A 10th child died has in a viral outbreak at a rehabilitation center in northern New Jersey, where 27 young patients with compromised immune systems have been confirmed with adenovirus infections, state health officials said. (Source: Reuters: Health)
Source: Reuters: Health - November 1, 2018 Category: Consumer Health News Tags: healthNews Source Type: news

10th child dies from adenovirus outbreak in New Jersey
A 10th child has died following an outbreak of adenovirus at a New Jersey rehabilitation facility, state health officials said. (Source: CNN.com - Health)
Source: CNN.com - Health - November 1, 2018 Category: Consumer Health News Source Type: news

Adenovirus
(Source: eMedicineHealth.com)
Source: eMedicineHealth.com - November 1, 2018 Category: General Medicine Source Type: news

Two more children contract adenovirus at New Jersey pediatric center
A 26th child has caught the adenovirus sweeping the Wanaque Center for Nursing and Rehabilitation, where the virus has killed nine. The Department of Health cited the hospital for poor hand-washing. (Source: the Mail online | Health)
Source: the Mail online | Health - October 31, 2018 Category: Consumer Health News Source Type: news

Cases of Mysterious Polio-Like Illness Continue to Rise. And Experts Are Frustrated Over a Lack of Answers
A rare, polio-like illness continues to spread across the United States, puzzling and concerning health officials who are investigating the mysterious condition. So far this year, the Centers for Disease Control and Prevention (CDC) has reported a total of 72 confirmed cases of acute flaccid myelitis (AFM) in 24 states, including clusters in Minnesota, Pennsylvania and Colorado. Ninety percent of confirmed diagnoses were in children younger than 18, according to the CDC. The agency is investigating another 119 patients in connection with the disease, which causes symptoms including sudden arm and leg weakness, loss of musc...
Source: TIME: Health - October 31, 2018 Category: Consumer Health News Authors: Jamie Ducharme Tags: Uncategorized healthytime Infectious Disease onetime Source Type: news

Infection Team Investigates NJ Rehab Facility
Adenovirus typically causes cold-like symptoms, but can be fatal in weakened patients. The children at Wanaque have developmental disorders or immune deficiencies. (Source: WebMD Health)
Source: WebMD Health - October 30, 2018 Category: Consumer Health News Source Type: news