A Newly Published Network Meta-Analysis (NMA) Found TREMFYA ® (guselkumab) Ranked Highest for Overall Level of Skin Clearance and Provided Positive Joint Efficacy Among Active Psoriatic Arthritis (PsA) Therapies
Conclusions (i.e., comparable) are based on an overlap of pairwise 95 percent credible intervals.1c. PASI 90 is defined as at least 90 percent improvement from baseline in the PASI score. The PASI score grades the amount of surface area on each body region that is covered by PsO plaques and the severity of plaques for their redness, thickness, and scaliness.13 PASI 90 was not a controlled endpoint in DISCOVER-1 or -2.8,9d. TREMFYA q4w dosing is not currently FDA-approved.2e. The PsA-modified vdH-S score combines erosion and joint space narrowing scores derived from radiographs of joints in body regions impacted by PsA.14 T...
Source: Johnson and Johnson - January 26, 2022 Category: Pharmaceuticals Tags: Innovation Source Type: news

Herpes Zoster Vaccine Can Save Your Patients' Eyesight Herpes Zoster Vaccine Can Save Your Patients' Eyesight
Herpes zoster ophthalmicus can be devastating. Dr Rapuano urges all ophthalmologists to discuss the zoster vaccine with their patients.Medscape Ophthalmology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - January 21, 2022 Category: Consumer Health News Tags: Ophthalmology Viewpoint Source Type: news

Can Neonatal Herpes Lead to Alzheimer ’s Disease?
MD/PhD candidate Abigail Dutton is looking for answers—from incurious mice. (Source: News at Dartmouth Medical School)
Source: News at Dartmouth Medical School - January 21, 2022 Category: Hospital Management Authors: NonPerson Geisel Web Service Acct Tags: News Research Source Type: news

Recommendations Updated for Recombinant Zoster Vaccine
THURSDAY, Jan. 20, 2022 -- Recommendations have been updated for use of the recombinant zoster vaccine (RZV) for prevention of herpes zoster and related complications among immunocompromised adults aged 19 years and older; the recommendations are... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - January 20, 2022 Category: Pharmaceuticals Source Type: news

Use of Recombinant Zoster Vaccine in Immunocompromised Adults Aged ≥19 Years: Recommendations of the Advisory Committee on Immunization Practices - United States, 2022
This report describes the ACIP recommendations for two doses of RZV to prevent herpes zoster and related complications in immunocompromised adults. (Source: CDC Morbidity and Mortality Weekly Report)
Source: CDC Morbidity and Mortality Weekly Report - January 20, 2022 Category: American Health Tags: Adult Health Adult Vaccinations Advisory Committee on Immunization Practices (ACIP) MMWR Morbidity & Mortality Weekly Report Shingles (Herpes Zoster) Shingles Vaccination Source Type: news

Pfizer and BioNTech sign new global collaboration agreement to develop first mRNA-based shingles vaccine
Pfizer Inc. (NYSE: PFE) and BioNTech SE (Nasdaq: BNTX) announced a new research, development and commercialization collaboration to develop a potential first mRNA-based vaccine for the prevention of shingles (herpes zoster virus, or HZV), a debilitating, disfiguring and painful disease that impacts about one in three people in the United States during their lifetime. (Source: World Pharma News)
Source: World Pharma News - January 6, 2022 Category: Pharmaceuticals Tags: Featured Business Business and Industry Source Type: news

UofL researchers reveal how oral bacteria suppress protection against viral growth
 Bacteria that cause periodontal disease reduce oral defense and increase viral growth By Betty Coffman LOUISVILLE, Ky. – Researchers from the University of Louisville School of Dentistry and their colleagues have discovered details of how proteins produced by oral epithelial cells protect humans against viruses entering the body through the mouth. They also found that oral bacteria can suppress the activity of the se cells, increasing vulnerability to infection. A family of proteins known as interferon lambdas produced by epithelial cells in the mouth serve to protect humans from viral infection, but...
Source: Dental Technology Blog - January 6, 2022 Category: Dentistry Source Type: news

Inquest announced for new mums who died from herpes
A surgeon who operated on the two women may have been the source of infection, a BBC investigation found. (Source: BBC News | Health | UK Edition)
Source: BBC News | Health | UK Edition - December 29, 2021 Category: Consumer Health News Source Type: news

NIDCR's Winter 2021 E-Newsletter
Having trouble viewing this email? View it as a Web page. NIDCR's Winter 2021 E-Newsletter In this issue: NIDCR News Funding Opportunities & Related Notices NIH/HHS News Subscribe to NIDCR News Science Advances   NIDCR News NIDCR Major Announcement: Save the Date! Mark your calendar for Tuesday, December 21, at 1pm for a major webcast announcement from NIDCR. Look for log-in instructions, coming in a separate NIDCR email next week. Jennifer Webster-Cyriaque Joins NIDCR as Deputy Director NIDCR welcomed Jennifer Webster-...
Source: NIDCR Science News - December 8, 2021 Category: Dentistry Source Type: news

Herpes Kidnaps Proteins to Take Up Residence in the Nervous System
The herpes virus hitches a ride to the nuclei of neurons from a surprising source. (Source: The Scientist)
Source: The Scientist - December 6, 2021 Category: Science Tags: Sponsored Article Source Type: news

STD symptoms: Early signs of the sexually transmitted disease found in your eyes
STD symptoms: The rate of STIs in 2019 was 832 cases per 100,000 population, that is an increase from the preceding four years. Annual cases of gonorrhoea, syphilis, and herpes have been increasing since 2010. Surprisingly, the disease is known to affect a person's eyes with any of these three symptoms being a warning. (Source: Daily Express - Health)
Source: Daily Express - Health - December 5, 2021 Category: Consumer Health News Source Type: news

Latest Phase 3 Data for First-in-Class TREMFYA ® (guselkumab) Demonstrates Significant and Durable Improvement in Signs and Symptoms of Active Psoriatic Arthritis while Maintaining its Safety Profile in Patients with Inadequate Response to Tumor Necrosis Factor Inhibition (TNFi-IR)
SPRING HOUSE, PENNSYLVANIA, December 3, 2021 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced new TREMFYA® (guselkumab) efficacy and safety data from the Phase 3b COSMOS trial published in Annals of the Rheumatic Diseases (ARD), evaluating this selective interleukin (IL)-23 inhibitor in adults with active psoriatic arthritis (PsA) who demonstrated inadequate efficacy or intolerance to tumor necrosis factor inhibition (TNFi).1 Results showed significantly higher proportions of patients treated with TREMFYA had improvement in joint signs and symptoms and complete skin clearance versus placeb...
Source: Johnson and Johnson - December 3, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news

Change to sepsis advice after mums' herpes deaths
Medical advice on how new mothers with sepsis should be treated is to change after two women died of a herpes infection. (Source: BBC News | Health | UK Edition)
Source: BBC News | Health | UK Edition - November 23, 2021 Category: Consumer Health News Source Type: news

New mothers who died of herpes could have been infected by one surgeon
Two mothers who died of herpes after ​having Caesareans could have been infected by a single surgeon, the BBC has found.  (Source: BBC News | Health | UK Edition)
Source: BBC News | Health | UK Edition - November 22, 2021 Category: Consumer Health News Source Type: news

Is Herpes Really an STD
? (Source: eMedicineHealth.com)
Source: eMedicineHealth.com - November 18, 2021 Category: General Medicine Source Type: news