Midlife mortality in White non-Hispanic male veterans enrolled in Department of Veterans Affairs primary care, 2003-2014 - Liu CF, Hebert P, Wong ES, Nelson K, Maynard C.
BACKGROUND: After years of decline in mortality rates in the United States, there have been increases in mortality rates in White non-Hispanic Americans ages 45-54, due to increases in deaths from suicide, poisoning, and alcoholic liver disease. OB... (Source: SafetyLit)
Source: SafetyLit - February 17, 2020 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Most Quality Metrics for Kidney Care in the US Fall Short Most Quality Metrics for Kidney Care in the US Fall Short
A new study from the American Society of Nephrology (ASN) Quality Committee shows nearly half of metrics to monitor care for kidney disease fail to meet criteria for being labeled as high quality.Medscape Medical News (Source: Medscape Internal Medicine Headlines)
Source: Medscape Internal Medicine Headlines - February 17, 2020 Category: Internal Medicine Tags: Nephrology News Source Type: news

A Failed Strategy for an Effective Bladder Cancer Drug A Failed Strategy for an Effective Bladder Cancer Drug
When the number of doses of BCG for high-grade non-muscle invasive bladder cancer was cut, outcomes were inferior in a randomized clinical trial.Medscape Medical News (Source: Medscape Urology Headlines)
Source: Medscape Urology Headlines - February 17, 2020 Category: Urology & Nephrology Tags: Hematology-Oncology News Source Type: news

New Devices for Kidney Stone Management New Devices for Kidney Stone Management
Get up-to-date on the most recent developments on devices for the surgical management of kidney stones.Current Opinion in Urology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - February 17, 2020 Category: Consumer Health News Tags: Urology Journal Article Source Type: news

Cutting off kidney cancer at its roots
(Max Delbr ü ck Center for Molecular Medicine in the Helmholtz Association) Scientists at the MDC have discovered stem cells responsible for the most common form of kidney cancer. The team of Walter Birchmeier has found a way to block the growth of these tumors in three models of the disease. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 17, 2020 Category: International Medicine & Public Health Source Type: news

Learn how to regenerate and repair your liver in upcoming "Fatty Liver Docu-Class" that begins Feb. 25th - register here
(Natural News) An upcoming docu-class produced by Global Health Solutions features a truly extraordinary collection of doctors, naturopaths and natural health experts (most of whom were interviewed in-studio) to produce the most comprehensive series of interviews ever offered on the subject of liver health. Given that we are now living in a world of super... (Source: NaturalNews.com)
Source: NaturalNews.com - February 16, 2020 Category: Consumer Health News Source Type: news

Telemarketer Access to Medicare Information to Be Investigated
Audit comes in response to surge of telemarketing scams targeting Medicare recipients (Source: Pulmonary Medicine News - Doctors Lounge)
Source: Pulmonary Medicine News - Doctors Lounge - February 15, 2020 Category: Respiratory Medicine Tags: Cardiology, Dermatology, Endocrinology, Family Medicine, Geriatrics, Gastroenterology, Gynecology, Infections, AIDS, Internal Medicine, Allergy, Nephrology, Neurology, Oncology, Ophthalmology, Orthopedics, ENT, Pharmacy, Psychiatry, Pulmonology, Rheumatol Source Type: news

U.S. Life Expectancy to Reach 85 by 2060
Census Bureau predicts life expectancy will increase by about six years between 2017 and 2060 (Source: Pulmonary Medicine News - Doctors Lounge)
Source: Pulmonary Medicine News - Doctors Lounge - February 15, 2020 Category: Respiratory Medicine Tags: Cardiology, Dermatology, Endocrinology, Family Medicine, Geriatrics, Gastroenterology, Gynecology, Infections, AIDS, Internal Medicine, Allergy, Critical Care, Emergency Medicine, Nephrology, Neurology, Nursing, Oncology, Ophthalmology, Orthopedics, ENT, Source Type: news

Getting lots of exercise tied to lower risk of kidney disease
(Reuters Health) - People who get plenty of physical activity may be less likely than their more sedentary counterparts to develop chronic kidney disease, a recent study suggests. (Source: Reuters: Health)
Source: Reuters: Health - February 14, 2020 Category: Consumer Health News Tags: healthNews Source Type: news

Hepatocellular Carcinoma: 5 Things to Know Hepatocellular Carcinoma: 5 Things to Know
Get up to speed on the latest data surrounding the most common form of liver cancer.Medscape Gastroenterology (Source: Medscape General Surgery Headlines)
Source: Medscape General Surgery Headlines - February 14, 2020 Category: Surgery Tags: Gastroenterology Commentary Source Type: news

China National Medical Products Administration grants approval of Roche ’s Tecentriq in combination with chemotherapy as first-line treatment of people with extensive-stage small cell lung cancer
Basel, 14 February 2020 – Roche (SIX: RO, ROG; OTCQX: RHHBY) today announced that China National Medical Products Administration (NMPA) has approved Tecentriq® (atezolizumab) in combination with chemotherapy (carboplatin and etoposide) for the first-line treatment of patients with extensive-stage small cell lung cancer (ES-SCLC).“Small cell lung cancer is an area of major unmet need in China and one that has seen limited advances until now,” said Levi Garraway, M.D., Ph.D., Chief Medical Officer and Head of Global Product Development. “This approval makes Tecentriq the first cancer immunotherapy...
Source: Roche Investor Update - February 14, 2020 Category: Pharmaceuticals Source Type: news

China National Medical Products Administration grants approval of Roche ’s Tecentriq in combination with chemotherapy as first-line treatment of people with extensive-stage small cell lung cancer
Basel, 14 February 2020 – Roche (SIX: RO, ROG; OTCQX: RHHBY) today announced that China National Medical Products Administration (NMPA) has approved Tecentriq® (atezolizumab) in combination with chemotherapy (carboplatin and etoposide) for the first-line treatment of patients with extensive-stage small cell lung cancer (ES-SCLC).“Small cell lung cancer is an area of major unmet need in China and one that has seen limited advances until now,” said Levi Garraway, M.D., Ph.D., Chief Medical Officer and Head of Global Product Development. “This approval makes Tecentriq the first cancer immunotherapy...
Source: Roche Media News - February 14, 2020 Category: Pharmaceuticals Source Type: news

Vitamin E effective, safe for fatty liver in HIV patients
(McGill University) A type of fatty liver disease that commonly affects patients with HIV can be safely treated with vitamin E, a McGill-led study has found. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 14, 2020 Category: International Medicine & Public Health Source Type: news

Green tea extract combined with exercise reduces fatty liver disease in mice
(Penn State) The combination of green tea extract and exercise reduced the severity of obesity-related fatty liver disease by 75% in mice fed a high-fat diet, according to Penn State researchers, whose recent study may point to a potential health strategy for people. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 14, 2020 Category: International Medicine & Public Health Source Type: news

New guidelines for hepatic failure in the intensive care unit
(Wolters Kluwer Health) For critical care specialists, hepatic failure poses complex challenges unlike those of other critical illnesses. A new set of evidence-based recommendations for management of liver failure is presented in the March issue of Critical Care Medicine, the official journal of the Society of Critical Care Medicine (SCCM). The journal is published in the Lippincott portfolio by Wolters Kluwer. The guidelines are being presented at the SCCM 49th Critical Care Congress. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 14, 2020 Category: International Medicine & Public Health Source Type: news

Chronic kidney disease kills more than 1M people annually worldwide
Chronic kidney disease has been described as a " global killer in plain sight " by the authors of a new analysis estimating the prevalence of the condition. (Source: Health News - UPI.com)
Source: Health News - UPI.com - February 14, 2020 Category: Consumer Health News Source Type: news

Study Shows No Benefit for Plasma Exchange in ANCA Vasculitis Study Shows No Benefit for Plasma Exchange in ANCA Vasculitis
In findings that raise questions about the go-to treatment for patients with antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis, researchers behind the PEXIVAS study have concluded that plasma exchange does not reduce the odds of death or end-stage kidney disease.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - February 13, 2020 Category: Consumer Health News Tags: Medscape Today News Source Type: news

Less Than Half of Kidney Disease Quality Metrics Rated Highly Valid
THURSDAY, Feb. 13, 2020 -- Less than half of the existing 60 kidney disease quality metrics are rated with high validity, according to a study published online Feb. 13 in the Journal of the American Society of Nephrology. Mallika L. Mendu, M.D.,... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - February 13, 2020 Category: Pharmaceuticals Source Type: news

What 'dry fasting' is and why you shouldn't do it
Your kidneys don't need to "reset," and your body really, really needs water. Please drink some water. (Source: L.A. Times - Health)
Source: L.A. Times - Health - February 13, 2020 Category: Consumer Health News Authors: Jessica Roy Source Type: news

Decipher GRID Signature Predicts Benefit from Chemotherapy in Men Diagnosed with Metastatic Prostate Cancer
SAN DIEGO, Feb. 13, 2020 -- (Healthcare Sales & Marketing Network) -- Decipher Biosciences, a commercial-stage precision oncology company committed to improving patient care, initially focused on urologic cancers, today announced that a Decipher GRID mole... Diagnostics, Oncology Decipher Biosciences, Decipher GRID, prostate cancer (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - February 13, 2020 Category: Pharmaceuticals Source Type: news

Novel targeted drug shows promise in advanced kidney cancer
(Dana-Farber Cancer Institute) Scientists report promising activity of a novel drug that targets a key molecular driver of clear cell renal cell carcinoma (ccRCC) in patients with metastatic disease. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - February 13, 2020 Category: Cancer & Oncology Source Type: news

2011 to 2018 Saw Decline in Problems Paying Medical Bills
Percent of persons in families with problems paying bills higher for women, children, non - Hispanic blacks (Source: The Doctors Lounge - Oncology)
Source: The Doctors Lounge - Oncology - February 13, 2020 Category: Cancer & Oncology Tags: Cardiology, Dermatology, Endocrinology, Family Medicine, Geriatrics, Gastroenterology, Gynecology, Infections, AIDS, Internal Medicine, Allergy, Critical Care, Emergency Medicine, Nephrology, Neurology, Nursing, Oncology, Ophthalmology, Orthopedics, ENT, Source Type: news

Virtual Crossmatching Allows Faster Kidney Transplantation Virtual Crossmatching Allows Faster Kidney Transplantation
Kidney transplantation can be safely performed with virtual crossmatching of donor and recipient without the need for a prospective physical crossmatch, according to a retrospective review.Reuters Health Information (Source: Medscape Transplantation Headlines)
Source: Medscape Transplantation Headlines - February 13, 2020 Category: Transplant Surgery Tags: Transplantation News Source Type: news

Most Quality Metrics for Kidney Disease Fall Short
A new study evaluated national kidney disease quality metrics and found that more than half were of middle or low quality. (Source: BWH News)
Source: BWH News - February 13, 2020 Category: Hospital Management Source Type: news

Circadian rhythms in the absence of the clock gene Bmal1
Circadian (~24 hour) clocks have a fundamental role in regulating daily physiology. The transcription factor BMAL1 is a principal driver of a molecular clock in mammals. Bmal1 deletion abolishes 24-hour activity patterning, one measure of clock output. We determined whether Bmal1 function is necessary for daily molecular oscillations in skin fibroblasts and liver slices. Unexpectedly, in Bmal1 knockout mice, both tissues exhibited 24-hour oscillations of the transcriptome, proteome, and phosphoproteome over 2 to 3 days in the absence of any exogenous drivers such as daily light or temperature cycles. This demonstrates a co...
Source: ScienceNOW - February 13, 2020 Category: Science Authors: Ray, S., Valekunja, U. K., Stangherlin, A., Howell, S. A., Snijders, A. P., Damodaran, G., Reddy, A. B. Tags: Engineering, Physiology reports Source Type: news

Bright idea in dentist's office leads to innovative smoking cessation project
Results from this study recently published online in Addiction found primary care physicians providing smokers with a free, two week starter kit of nicotine replacement therapy (NRT) increased quit attempts While sitting in the dentist's office, Hollings Cancer Center researcher Matthew Carpenter, Ph.D., of the Medical University of South Carolina, had a bright idea. As he received his goody bag with dental hygiene products, he wondered why not conduct a study and have primary care providers do the same thing for their patients who use tobacco. The bags would contain educational material, free lozenges and tobacco cessati...
Source: Dental Technology Blog - February 12, 2020 Category: Dentistry Source Type: news

Study Identifies Drugs of Concern for Patients With CKD
A team of Canadian researchers has developed a list of three dozen medications that must or could be dose-adjusted or avoided in patients with chronic kidney disease. (Source: AAFP News)
Source: AAFP News - February 12, 2020 Category: Primary Care Source Type: news

Survival Similar for Hemodialysis, Peritoneal Dialysis
WEDNESDAY, Feb. 12, 2020 -- Peritoneal dialysis (PD) and in-center hemodialysis (HD) carry similar survival benefits, according to a review published online Jan. 28 in Nephrology Dialysis Transplantation. Mohamed E. Elsayed, M.B.B.S., from... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - February 12, 2020 Category: Pharmaceuticals Source Type: news

Rates of Liver Disease High Among World Trade Center Responders
WEDNESDAY, Feb. 12, 2020 -- World Trade Center (WTC) responders have a three times higher rate of liver disease compared with non-WTC responders, according to a study recently published in Clinical Imaging. Xiangmeng Chen, from the Icahn School of... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - February 12, 2020 Category: Pharmaceuticals Source Type: news

Tackling the Weight List Problem Tackling the Weight List Problem
Laparoscopic sleeve gastrectomy may help improve kidney transplant candidacy among morbidly obese patients, but important questions remain.American Journal of Transplantation (Source: Medscape General Surgery Headlines)
Source: Medscape General Surgery Headlines - February 12, 2020 Category: Surgery Tags: Transplantation Journal Article Source Type: news

SGLT2 Inhibition: A New Avenue to Protect the Kidney SGLT2 Inhibition: A New Avenue to Protect the Kidney
Could SGLT2 inhibitors have a role in the management of patients with kidney disease? What are the benefits of these agents?Nephrology Dialysis Transplantation (Source: Medscape General Surgery Headlines)
Source: Medscape General Surgery Headlines - February 12, 2020 Category: Surgery Tags: Nephrology Journal Article Source Type: news

Researchers find test to ID children at higher risk for cystic fibrosis liver disease
(University of Colorado Anschutz Medical Campus) A major multi-center investigation of children with cystic fibrosis has identified a test that allows earlier identification of those at risk for cystic fibrosis liver disease. The study, which includes 11 clinical sites in North America, was led by Michael Narkewicz, MD, professor of pediatrics from the University of Colorado School of Medicine and Children's Hospital Colorado. The findings of the study are published today ahead of print in The Journal of Pediatrics. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 12, 2020 Category: International Medicine & Public Health Source Type: news

Contraindication: Taking CBD can multiply the negative effects of acetaminophen-induced liver damage
(Natural News) Acetaminophen is one of the most abused over-the-counter drugs. Countless families needlessly use acetaminophen to reduce a fever, interfering with a vital function of the immune system, delaying one’s ability to recover from an infection. According to the Consumer Healthcare Products Association, acetaminophen is found in over 600 OTC products and is used... (Source: NaturalNews.com)
Source: NaturalNews.com - February 12, 2020 Category: Consumer Health News Source Type: news

Cardiovascular Functional Reserve Improves After Kidney Transplant Cardiovascular Functional Reserve Improves After Kidney Transplant
Improved cardiovascular reserve was seen 1 year after kidney transplantation in the absence of significant alterations in left ventricular muscle mass in the CAPER study.Medscape Medical News (Source: Medscape Cardiology Headlines)
Source: Medscape Cardiology Headlines - February 12, 2020 Category: Cardiology Tags: Cardiology News Source Type: news

This drug maker's kidney disease treatment scores $50M payday
FibroGen Inc. will receive $50 million from partner AstraZeneca after federal regulators accepted the San Francisco company's application to approve a drug for treating anemia in chronic kidney disease patients. Acceptance of FibroGen's new drug application for the drug, called roxadustat, by the Food and Drug Administration means AstraZeneca plc (NYSE: AZN) must pay $50 million to FibroGen, the company said in a Securities and Exchange Commission filing Tuesday. Roxadustat, an oral small-molecule… (Source: bizjournals.com Health Care:Pharmaceuticals headlines)
Source: bizjournals.com Health Care:Pharmaceuticals headlines - February 12, 2020 Category: Pharmaceuticals Authors: Ron Leuty Source Type: news

This drug maker's kidney disease treatment scores $50M payday
FibroGen Inc. will receive $50 million from partner AstraZeneca after federal regulators accepted the San Francisco company's application to approve a drug for treating anemia in chronic kidney disease patients. Acceptance of FibroGen's new drug application for the drug, called roxadustat, by the Food and Drug Administration means AstraZeneca plc (NYSE: AZN) must pay $50 million to FibroGen, the company said in a Securities and Exchange Commission filing Tuesday. Roxadustat, an oral small-molecule… (Source: bizjournals.com Health Care:Biotechnology headlines)
Source: bizjournals.com Health Care:Biotechnology headlines - February 12, 2020 Category: Biotechnology Authors: Ron Leuty Source Type: news

Virtual Cross-Matching May Speed Kidney Transplant Process
TUESDAY, Feb. 11, 2020 -- Virtual cross-matching may reduce cold ischemia time (CIT) for donor organs in kidney transplants, according to a study published online Feb. 5 in the Journal of the American College of Surgeons. Vinayak S. Rohan, M.D.,... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - February 11, 2020 Category: Pharmaceuticals Source Type: news

A systematic review of genitourinary injuries arising from rugby and football - Kim JK, Koyle MA, Lee MJ, Nason GJ, Ren LY, O'Kelly F.
BACKGROUND: Genitourinary injuries in athletes engaging in high-impact sports such as football and rugby may have catastrophic consequences, especially in individuals with pre-existing urologic concerns, such as a solitary kidney. OBJECTIVE: To sum... (Source: SafetyLit)
Source: SafetyLit - February 11, 2020 Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news

Drug Combo No Better in MRSA Blood Infections, Ups Risk Drug Combo No Better in MRSA Blood Infections, Ups Risk
Adding a beta-lactam to standard therapy for MRSA bacteremia does not improve outcomes and appears to up the risk for kidney injury, data from a randomized controlled trial showed.Medscape Medical News (Source: Medscape Internal Medicine Headlines)
Source: Medscape Internal Medicine Headlines - February 11, 2020 Category: Internal Medicine Tags: Infectious Diseases News Source Type: news

925049 925049
Scores of organs -- mostly kidneys -- are trashed each year, and many more become critically delayed while being shipped on commercial airliners, a new investigation finds.Kaiser Health News (Source: Medscape General Surgery Headlines)
Source: Medscape General Surgery Headlines - February 11, 2020 Category: Surgery Tags: Transplantation News Source Type: news

How Lifesaving Organs for Transplant Go Missing in Transit How Lifesaving Organs for Transplant Go Missing in Transit
Scores of organs -- mostly kidneys -- are trashed each year, and many more become critically delayed while being shipped on commercial airliners, a new investigation finds.Kaiser Health News (Source: Medscape Critical Care Headlines)
Source: Medscape Critical Care Headlines - February 11, 2020 Category: Intensive Care Tags: Transplantation News Source Type: news

Metabolic Syndrome, But Not NAFLD, Increases 10-year Mortality Metabolic Syndrome, But Not NAFLD, Increases 10-year Mortality
This study compared 10-year mortality among those with and without NAFLD in an urban South Asia cohort. What factors were associated with early risk of death?Liver International (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - February 11, 2020 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Why this Island woman is giving part of her liver to a complete stranger
A woman from Tignish, P.E.I., will soon be making a trip to Toronto to donate part of her liver to a complete stranger. (Source: CBC | Health)
Source: CBC | Health - February 11, 2020 Category: Consumer Health News Tags: News/Canada/PEI Source Type: news

Many Patients With NAFLD Should Be Screened for Liver Cancer, Experts Say Many Patients With NAFLD Should Be Screened for Liver Cancer, Experts Say
Screening and surveillance for hepatocellular carcinoma (HCC) is important in many patients with nonalcoholic fatty liver disease (NAFLD), according to an expert panel of the American Gastroenterological Association (AGA).Reuters Health Information (Source: Medscape Pathology Headlines)
Source: Medscape Pathology Headlines - February 11, 2020 Category: Pathology Tags: Gastroenterology News Source Type: news

PIONEER milestone - First two datasets uploaded into the PIONEER Big Data platform
(European Association of Urology) In an important step forward the first datasets have been transferred into the PIONEER Big Data platform by PIONEER partner Erasmus University Medical Centre (MC). Through the application of Big Data and the analyses of real-world evidence PIONEER aims to change the prostate cancer landscape to improve the health and social care received by all prostate cancer patients and their families. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - February 11, 2020 Category: Cancer & Oncology Source Type: news

UC research could help reduce disease incidence in organ donors
(University of Cincinnati) Researchers at the University of Cincinnati are among the first to adopt genotyping that helps identify and predict the risk accompanying individuals wishing to donate a kidney. Those who are high-risk of developing disease can be removed from the pool of potential donors which will reduce their chances of developing kidney disease. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 11, 2020 Category: International Medicine & Public Health Source Type: news

Janssen Announces Submission to U.S. FDA for New DARZALEX ® (Daratumumab)-Based Combination Regimen for Patients with Relapsed/Refractory Multiple Myeloma
RARITAN, NJ, February 10, 2020 – The Janssen Pharmaceutical Companies of Johnson & Johnson announced today the submission of a supplemental Biologics License Application (sBLA) to the U.S. Food and Drug Administration (FDA) seeking approval of DARZALEX® (daratumumab) in combination with Kyprolis® (carfilzomib) and dexamethasone (DKd) for relapsed/refractory multiple myeloma. The sBLA is supported by results from the Phase 3 CANDOR study, which compared treatment with DKd to carfilzomib and dexamethasone (Kd) in patients with multiple myeloma who relapsed after one to three prior lines of therapy. “W...
Source: Johnson and Johnson - February 10, 2020 Category: Pharmaceuticals Tags: Innovation Source Type: news

Dronedarone: Implications for Its Use in Atrial Fibrillation Dronedarone: Implications for Its Use in Atrial Fibrillation
This review summarizes real-world evidence on safety and efficacy of dronedarone, focusing on liver safety, mortality risk in patients with paroxysmal/persistent AF, and interactions with DOACs.Europace (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - February 10, 2020 Category: Consumer Health News Tags: Cardiology Journal Article Source Type: news

Effect of Estradiol on Penile Erection Effect of Estradiol on Penile Erection
Could elevated estradiol levels negatively affect erectile function?Translational Andrology and Urology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - February 10, 2020 Category: Consumer Health News Tags: Urology Journal Article Source Type: news

Liver cancer symptoms: Pain in this area of the stomach could signal the deadly disease
LIVER cancer symptoms can include feeling full after eating small amounts and feeling sick, but what are other telling signs of the deadly disease? (Source: Daily Express - Health)
Source: Daily Express - Health - February 9, 2020 Category: Consumer Health News Source Type: news