Hippocratic AI Raises $53 Million Series A at a $500 Million Valuation
Company Releases First Product: Generative AI-Powered Staffing Marketplace for Healthcare and will use Funds to Accelerate Further Product Development and Conduct Phase Three Safety Testing for its LLM Hippocratic AI, the company building the first safety-focused Large Language Model (LLM) for healthcare, today announced the close of a $53 million Series A funding round at a $500 million valuation, bringing total funding to $120 million. Today, the company also released its first product for phase three safety testing: a staffing marketplace for healthcare where health systems, payors, and others can “hire” generative ...
Source: EMR and HIPAA - April 22, 2024 Category: Information Technology Authors: Healthcare IT News Tags: Health IT Company Healthcare IT a16z Andreessen Horowitz Bio Health Capsule Cincinnati Children’s ELNA Evernow Fraser Health General Catalyst Guidehealth HarmonyCares Health IT Funding Health IT Fundings Health IT Investmen Source Type: blogs

Fight Aging! Newsletter, April 22nd 2024
This study reveals a potential treatment for human mitochondrial diseases. « Back to Top A Population Study Correlates Air Pollution with Faster Cognitive Aging https://www.fightaging.org/archives/2024/04/a-population-study-correlates-air-pollution-with-faster-cognitive-aging/ A number of large epidemiological studies provide evidence for long-term exposure to greater levels of air pollution to accelerate the onset and progression of age-related disease. A few of these manage to control for the tendency for wealthier people to avoid living in areas with higher particulate air pollution, ...
Source: Fight Aging! - April 21, 2024 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

The Evolution of Healthcare at Home, the Technology Driving this Change, and It ’ s Impact on the World of Healthcare
The world of healthcare is ever-evolving, especially when new technology is being adopted. One such new area is healthcare at home. Although we were forced into fully remote operations with COVID-19, we have been making modifications along the way and have discovered how beneficial it can be to our organizations and our patients. To make further strides though, we have to understand where we’ve come from, where we are now, and how it is making an impact. So let’s take a deeper look into healthcare at home to see how it has evolved over time, the technology that is driving this change, and how it is impacting ou...
Source: EMR and HIPAA - April 19, 2024 Category: Information Technology Authors: Grayson Miller Tags: Communication and Patient Experience Health IT Company Healthcare IT Telemedicine and Remote Monitoring Academy Medtech Ventures Alaina Victoria Brenden Hayden Cara Lunsford Carrie Nelson Cindy Gaines Digital Communication Discern He Source Type: blogs

Bis(monoacylglycero)phosphates Accumulate in Aged Tissues
Lipid metabolism is changed and disrupted with advancing age, as is the case for all complex mechanisms in the body. There are a great many different lipids present in the body; even the list of classes of lipid is a long one. Finding specific changes that relate to aging can be interesting, but the challenge lie in better understanding how those changes come about, and whether they causes significant harm to tissues. Many age-related changes in molecular biochemistry are far downstream of the important causes of aging and do not cause much further disruption in and of themselves. In recent years, laboratory resea...
Source: Fight Aging! - April 19, 2024 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Harnessing Digital Innovation to Unlock Cancer Discoveries
By DOUG MIRSKY & BRIAN GONZALEZ What if digital innovations could be the key to reducing the burden of cancer? CancerX was founded in 2023 as part of the Cancer Moonshot to achieve this goal. By uniting leading minds across industries such as technology, healthcare, science, and government, we are breaking down silos and leveraging digital innovation in the fight against cancer. With ambitious goals to cut the death rate from cancer by at least 50% and to improve the experience of people who are affected by cancer, digital innovation is critical. As a public-private partnership co-hosted by Moffitt Cancer Center ...
Source: The Health Care Blog - April 19, 2024 Category: Consumer Health News Authors: matthew holt Tags: Health Policy Health Tech Brian Gonzalez CancerX Digital Medicine Society Doug Mirsky Moffitt Cancer Center Source Type: blogs

An Interview with Reason of Repair Biotechnologies on Reversal of Atherosclerosis
As some of you may know, I co-founded Repair Biotechnologies with Bill Cherman. The company is presently on the development of a gene therapy approach now demonstrated to rapidly reverse atherosclerosis in mice, the condition in which fatty plaques grow to narrow blood vessels and weaken blood vessel walls. One of the possible approaches to treating aging as a medical condition is to take the list of causes of human mortality, start at the top, and work down. Atherosclerosis is the single largest cause of death in our species, through the rupture of unstable atherosclerotic plaque leading to heart attack or stroke. The bur...
Source: Fight Aging! - April 18, 2024 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Fight Aging! Newsletter, April 15th 2024
In conclusion, although several clinical trials targeting SnCs are ongoing, various questions about the biology of SnCs remain open, resulting in a gap between molecular and cellular data. Concerning the need, initiatives such as SenNet aiming to create openly accessible atlases of SnCs should contribute enormously to the area. Advances in understanding the subcellular structure, the heterogeneity, and the dynamics of SnCs require the integration of molecular and cellular techniques with data analysis packages to evaluate high throughput evidence from microscopy and flow cytometry. It is also necessary to develop new equip...
Source: Fight Aging! - April 14, 2024 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

An Update on Reversal of Atherosclerosis at Repair Biotechnologies
As some of you know, Repair Biotechnologies is the company I co-founded with Bill Cherman back in 2018. We've been working on an approach to reverse atherosclerosis for much of that time, and matters have progressed through the stage of great data in mice to present preparations for a pre-IND meeting with the FDA. While excess cholesterol has long been understood to be important to the development of atherosclerosis, it turns out that circulating cholesterol bound to LDL particles is less important than the amount of localized excess cholesterol in the liver and blood vessel walls. Any localized excess of cholestero...
Source: Fight Aging! - April 11, 2024 Category: Research Authors: Reason Tags: Longevity Industry Source Type: blogs

Know About Cardiogenic Shock
When the heart is not able to pump enough blood for the needs of the body and the blood pressure falls, it is known as cardiogenic shock. Most important cause of cardiogenic shock is a heart attack. It is more likely to occur in those who are older, having blocks in multiple blood vessels of the heart, and in those with a previous heart attack. Cardiogenic shock is a potentially life threatening condition and needs urgent treatment. Even with treatment about half of those with cardiogenic shock might die. Those with cardiogenic shock may have severe shortness of breath, weak pulse, rapid heart-beats, low blood pressure, un...
Source: Cardiophile MD - April 10, 2024 Category: Cardiology Authors: Johnson Francis Tags: General Cardiology Source Type: blogs

LyGenesis Commences Phase II Trial for Growth of Liver Organoids in Patient Lymph Nodes
LyGenesis has been working towards liver organoid transplantation as a treatment for liver failure for some years now. Organs such as the liver, thymus, and a few others do not need to be in any specific place in the body to carry out many of their varied functions. Some of the vital work of the liver, for example, can be conducted in small organoids grown from liver cells transplanted into lymph nodes or other parts of the body that can act as stable bioreactors. Even setting aside the possibility of growing functional liver organoids from patient cells or universal cell lines, it is worth noting that the old appro...
Source: Fight Aging! - April 9, 2024 Category: Research Authors: Reason Tags: Longevity Industry Source Type: blogs

What is the reason for sudden breathlessness at night in those with heart disease?
Sudden breathlessness at night in those with known heart disease is usually due to collection of fluid in the lungs (pulmonary edema). During day time, when one is walking about, any extra fluid in the body tends to collect in the legs, due to the effect of gravity. Extra fluid in the body can occur due to failure of heart, kidneys, liver and rarely due to other causes. In heart failure, the extra fluid is due to inability of the heart to pump out blood well. This can occur if the heart muscle is weak or there is obstruction to a valve regulating the flow of blood inside the heart. At night, when one is lying down, extra f...
Source: Cardiophile MD - April 8, 2024 Category: Cardiology Authors: Johnson Francis Tags: General Cardiology Source Type: blogs

Common pitfalls underlying cause-and-effect relationships
In the realm of medicine, cause-and-effect relationships are those where a specific cause, such as a disease, condition, or treatment, directly leads to a specific outcome or effect. An example of this is the established fact that smoking causes lung cancer. Similarly, it is well-documented that regular, heavy alcohol consumption directly leads to liver cirrhosis. Read more… Common pitfalls underlying cause-and-effect relationships originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - April 1, 2024 Category: General Medicine Authors: Tags: Physician Psychiatry Source Type: blogs

Bonus Features – March 31, 2024 – 55% of Change Healthcare customers expect adverse impacts on patient care, a mobile app helped 84% of seniors lower their blood pressure after 6 months, plus 19 more stories
This article will be a weekly roundup of interesting stories, product announcements, new hires, partnerships, research studies, awards, sales, and more. Because there’s so much happening out there in healthcare IT we aren’t able to cover in our full articles, we still want to make sure you’re informed of all the latest news, announcements, and stories happening to help you better do your job. News The State Department is offering a reward of up to $10 million for information about the ALPHV BlackCat ransomware-as-a-service group that was behind the Change Healthcare cyberattack. A report from HFMA and Eliciting Insig...
Source: EMR and HIPAA - March 31, 2024 Category: Information Technology Authors: Brian Eastwood Tags: Healthcare IT AdvancedMD Bitsight Carequality CENTEGIX CentralReach Closed Loop Medicine David Stevens Diligent Eliciting Insights Experity FrontRunnerHC Healthcare IT Today Bonus Features Hello Heart HFMA Incite Strategic Pa Source Type: blogs

Fight Aging! Newsletter, April 1st 2024
This study supports the proposed model that aging-related loss of colonic crypt epithelial cell AMP gene expression can promote increased relative abundances of Gn inflammaging-associated bacteria and gene expression markers of colonic inflammaging. These data may support new targets for aging-related therapies based on intestinal genes and microbiomes. « Back to Top A Skeptical View of the Role of Nuclear DNA Damage in Aging https://www.fightaging.org/archives/2024/03/a-skeptical-view-of-the-role-of-nuclear-dna-damage-in-aging/ It is evident and settled that stochastic nuclear DNA damag...
Source: Fight Aging! - March 31, 2024 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Wide Complex Tachycardia -- VT, SVT, or A Fib with RVR? If SVT, is it AVNRT or AVRT?
A 69 y.o. male with pertinent past medical history including Atrial fibrillation, atrial flutter, cardiomyopathy, Pulmonary Embolism, and hypertension presented to the Emergency Department via ambulance for respiratory distress and tachycardia. Per EMS report, patient believes he has been in atrial fibrillation for 5 days, since coming down with flu-like illness with rhinorrhea, productive cough, SOB. Patient is on rivaroxaben, carvedilol, and dofetilide (to suppress atrial fib -- rhythm control).  He states that he maybe missed a dose or two during recent illness. On EMS arrival, patient ' s oxygen sat...
Source: Dr. Smith's ECG Blog - March 28, 2024 Category: Cardiology Authors: Steve Smith Source Type: blogs