Race to find a cure for heartbreaking disease which slowly killed baby Indi Gregory
Indi Gregory's heartbreaking battle with the disease has shone fresh light on mitochondrial disease, a catch-all term for genetic disorders caused by mutations in mitochondria. (Source: the Mail online | Health)
Source: the Mail online | Health - November 13, 2023 Category: Consumer Health News Source Type: news

A New Clue Into the Cause, Spread of Parkinson's Disease? A New Clue Into the Cause, Spread of Parkinson's Disease?
Damaged mitochondrial DNA initiates and spreads Parkinson ' s disease pathology, potentially opening new avenues for early diagnosis, researchers say.Medscape Medical News (Source: Medscape Pathology Headlines)
Source: Medscape Pathology Headlines - October 6, 2023 Category: Pathology Tags: Neurology & Neurosurgery News Source Type: news

AbbVie Exercises Exclusive Right to Acquire Mitokinin, Further Strengthening Neuroscience Pipeline
Mitokinin's lead compound, a selective PINK1 activator, is designed to address mitochondrial dysfunction, which plays a key role in the pathogenesis of Parkinson's disease Activation of PINK1 remediates mitochondrial damage and restores mitochondrial fu... Biopharmaceuticals, Neurology, Mergers & Acquisitions AbbVie, Mitokinin, Parkinson's Disease (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - October 5, 2023 Category: Pharmaceuticals Source Type: news

UMDF, MitoAction Help Lift Up Patient Voices on FDA Listening Session for Pyruvate Dehydrogenase Complex Deficiency (PDCD)
The United Mitochondrial Disease Foundation and MitoAction share their reactions to a September 8, 2023 listening session with the U.S. Food and Drug Administration regarding Pyruvate Dehydrogenase Complex Deficiency (PDCD). PITTSBURGH, Sept. 15, 2023 /PRNewswire-PRWeb/ -- Today, patient... (Source: PRWeb: Medical Pharmaceuticals)
Source: PRWeb: Medical Pharmaceuticals - September 15, 2023 Category: Pharmaceuticals Tags: FDA NPT Source Type: news

New blood test for Parkinson ’s could help doctors to detect it earlier
Researchers have developed a PCR assay to detect higher levels of mitochondrial DNA damage in blood cells. A new blood test could detect Parkinson’s disease earlier and help to determine who might benefit from specific treatments. Parkinson’s is a progressive brain condition that causes shaking,…#pcr #lauriesanders #dukeuniversitys #sanders (Source: Reuters: Health)
Source: Reuters: Health - September 1, 2023 Category: Consumer Health News Source Type: news

A blood test for Parkinson ’s disease?
Parkinson’s disease, a brain disorder that gradually leads to difficulty moving, tremors, and usually dementia by the end, is often difficult to diagnose early in its yearslong progression. That makes testing experimental treatments challenging and slows people from getting existing drugs, which can’t stop the ongoing death of brain cells but temporarily improve many of the resulting symptoms. Now, a study using rodents and tissue from diagnosed Parkinson’s patients suggests DNA damage spotted in blood samples offers a simple way to diagnose the disease early. Although the potential test needs to be validated i...
Source: ScienceNOW - August 30, 2023 Category: Science Source Type: news

Parkinson ’ s Patients Get More Mobility And Better Balance With Whole Body Vibration Therapy
I’ve always believed that with a little coaxing, your body can self-heal – and the same is true for your brain. Conventional doctors will never tell you this. For them, being a physician means managing symptoms with Big Pharma meds. But for years, I’ve been helping patients recover using dietary changes, lasers, stem cells, and hyperbaric oxygen (HBOT). These therapies help your body heal itself. No Big Pharma drug can do this. But I recently began researching another natural therapy – called Whole Body Vibration, or WBV – that can help Parkinson’s patients regain their mobility and balance. WBV isn’t new. It...
Source: Al Sears, MD Natural Remedies - August 28, 2023 Category: Complementary Medicine Authors: Jacob Tags: Anti-Aging Health Natural Cures Source Type: news

Long COVID: Mitochondria, the Big Miss, and Hope Long COVID: Mitochondria, the Big Miss, and Hope
This week there was news on Long COVID: emergence of data to support mitochondrial dysfunction as a potential cause, and learning how $1.15 billion to the NIH RECOVER initiative has largely been wasted.Medscape Medical News (Source: Medscape Infectious Diseases Headlines)
Source: Medscape Infectious Diseases Headlines - August 15, 2023 Category: Infectious Diseases Tags: Infectious Diseases News Source Type: news

Epigenetic embedding of childhood adversity: mitochondrial metabolism and neurobiology of stress-related CNS diseases - Bigio B, Sagi Y, Barnhill O, Dobbin J, El Shahawy O, de Angelis P, Nasca C.
This invited article ad memoriam of Bruce McEwen discusses emerging epigenetic mechanisms underlying the long and winding road from adverse childhood experiences to adult physiology and brain functions. The conceptual framework that we pursue suggest multi... (Source: SafetyLit)
Source: SafetyLit - August 14, 2023 Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news

Wake Forest University School of Medicine study examines tech to reverse damage to kidneys and kidney cells
According to the National Kidney Foundation, more than 100,000 Americans are waiting for a kidney transplant, and the demand for donated kidneys far exceeds the supply. In fact, only 25,498 kidney transplants were performed in 2022, and kidney disease impacts 37 million people in the U.S. But a new preclinical study, led by scientists at Wake Forest University School of Medicine, shows that a new technology called mitochondrial transplantation holds promise as a potential therapy that could change … (Source: bizjournals.com Health Care:Pharmaceuticals headlines)
Source: bizjournals.com Health Care:Pharmaceuticals headlines - August 14, 2023 Category: Pharmaceuticals Authors: Atrium Health Wake Forest Baptist Source Type: news

What is the Diagnostic Yield for Genetic Testing of Children with Neurodevelopmental Delays?
Discussion Children having significant neurodevelopmental disabilities are common with 17% of 3-17 year olds children having some type of such disability. Many are recommended to have genetic testing. Three main reasons for testing are determining the etiology, potential availability of targeted treatment or intervention, and determination of recurrence risk. But there are other pros and some cons to genetic testing which include: Pros Diagnosis is determined Improved understanding of diagnosis, natural history and prognosis for patient and family including decreased anxiety/guilt “Can end the diagnostic odyssey...
Source: PediatricEducation.org - July 10, 2023 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

This Molecule Is The Key To Stopping Autoimmune Disease
I’m seeing an epidemic of autoimmune diseases in my practice. My patients come to me when doctor after doctor has ignored their symptoms or given up on them. You see, the problem is that most doctors still don’t understand these diseases. I’m talking about things like lupus… rheumatoid arthritis… fibromyalgia… chronic fatigue syndrome… inflammatory bowel disease… and multiple sclerosis (MS). Of course, there are many more. About 80 conditions affecting organs throughout the body are known as autoimmune disorders. They affect around 50 million Americans. These are all conditions where your immune system beco...
Source: Al Sears, MD Natural Remedies - May 25, 2023 Category: Complementary Medicine Authors: Jacob Tags: Anti-Aging Health Natural Cures Source Type: news

First UK baby born with DNA from three people: what happens next? – podcast
The pioneering IVF procedure known as mitochondrial donation therapy (MDT) could prevent thousands of children from being born with devastating mitochondrial diseases. Madeleine Finlay speaks to Prof Darren Griffin, an expert in genetic diseases and reproduction, about how MDT works, the ethical considerations attached, and what techniques like it could mean for the future of reproductionRead science editor Ian Sample ’s exclusive coverage of this storyhereClip: Sky NewsContinue reading... (Source: Guardian Unlimited Science)
Source: Guardian Unlimited Science - May 11, 2023 Category: Science Authors: Presented and produced by Madeleine Finlay with Prof Darren Griffin, sound design by Tony Onuchukwu, the executive producer is Ellie Bury Tags: Science Genetics Biology IVF Source Type: news

First UK baby with DNA from three people born after new IVF procedure
Exclusive: Mitochondrial donation treatment aims to prevent children from inheriting incurable diseasesThe first UK baby created with DNA from three people has been born after doctors performed a groundbreaking IVF procedure that aims to prevent children from inheriting incurable diseases.The technique, known asmitochondrial donation treatment (MDT), uses tissue from the eggs of healthy female donors to create IVF embryos that are free from harmful mutations their mothers carry and are likely to pass on to their children.Continue reading... (Source: Guardian Unlimited Science)
Source: Guardian Unlimited Science - May 9, 2023 Category: Science Authors: Ian Sample Science editor Tags: Science Health Genetics Biology Society Source Type: news

Drug Hints at Benefit for Long COVID Fatigue in Small Trial
(MedPage Today) -- An investigational therapy for long COVID failed to improve measures of mitochondrial function in a small randomized study, but the oral drug did show potential for easing patients' fatigue. Four weeks of treatment with the... (Source: MedPage Today Infectious Disease)
Source: MedPage Today Infectious Disease - April 15, 2023 Category: Infectious Diseases Source Type: news