WHO Panel Calls for Registry of All Human Gene Editing Research WHO Panel Calls for Registry of All Human Gene Editing Research
It would be irresponsible for any scientist to conduct human gene-editing studies in people, and a central registry of research plans should be set up to ensure transparency, World Health Organization experts said on Tuesday.Reuters Health Information (Source: Medscape Pathology Headlines)
Source: Medscape Pathology Headlines - March 20, 2019 Category: Pathology Tags: Pathology & Lab Medicine News Source Type: news

Fact-Checking Finds Many Errors in Published Nucleotide-Sequence Reagents Fact-Checking Finds Many Errors in Published Nucleotide-Sequence Reagents
A semiautomated fact-checking tool, the Seek& Blastn tool, has found numerous errors in nucleotide-sequence reagents in biomedical research publications, researchers report.Reuters Health Information (Source: Medscape Pathology Headlines)
Source: Medscape Pathology Headlines - March 20, 2019 Category: Pathology Tags: Pathology & Lab Medicine News Source Type: news

Novel Handheld Device Detects High-Risk HPV in 2 Hours Novel Handheld Device Detects High-Risk HPV in 2 Hours
Several innovative strategies are successfully detecting high-risk human papillomavirus (HPV) types with technologies that do not require a resource-rich setting to perform well.Medscape Medical News (Source: Medscape Pathology Headlines)
Source: Medscape Pathology Headlines - March 19, 2019 Category: Pathology Tags: Hematology-Oncology News Source Type: news

Lung-Cancer Screens Effective in Asbestos-Exposed Smokers Lung-Cancer Screens Effective in Asbestos-Exposed Smokers
Low-dose computed tomography (LDCT) screening can detect early lung cancers in smokers with a history of occupational asbestos exposure, new research shows.Reuters Health Information (Source: Medscape Pathology Headlines)
Source: Medscape Pathology Headlines - March 18, 2019 Category: Pathology Tags: Hematology-Oncology News Source Type: news

Fewer T1 Melanoma Nodal Biopsies After 2009 Staging Manual Fewer T1 Melanoma Nodal Biopsies After 2009 Staging Manual
The overall number of T1 melanomas undergoing nodal biopsy have decreased following the 7th edition of the AJCC Cancer Staging Manual (AJCC 7), according to a new study.Reuters Health Information (Source: Medscape Pathology Headlines)
Source: Medscape Pathology Headlines - March 17, 2019 Category: Pathology Tags: Hematology-Oncology News Source Type: news

Distinct Clinical Subgroups In Early-Onset Colorectal Cancer Distinct Clinical Subgroups In Early-Onset Colorectal Cancer
Patients 18 to 29 years of age and those with IBD are genetically unique and require special consideration, say researchers.Medscape Medical News (Source: Medscape Pathology Headlines)
Source: Medscape Pathology Headlines - March 13, 2019 Category: Pathology Tags: Hematology-Oncology News Source Type: news

Gene-Expression Signature in Blood Predicts Kidney Graft Rejection Gene-Expression Signature in Blood Predicts Kidney Graft Rejection
A multivariable gene-expression signature in peripheral blood of kidney-transplant recipients allows early identification of T cell-mediated rejection, according to results from the KALIBRE study.Reuters Health Information (Source: Medscape Pathology Headlines)
Source: Medscape Pathology Headlines - March 13, 2019 Category: Pathology Tags: Nephrology News Source Type: news

Extended Lymph Node Dissection Safe in Gastroesophageal Carcinoma Extended Lymph Node Dissection Safe in Gastroesophageal Carcinoma
Extended lymphadenectomy (LAD) to improve staging accuracy for gastroesophageal carcinoma (GEC) can be done safely, according to a new case series.Reuters Health Information (Source: Medscape Pathology Headlines)
Source: Medscape Pathology Headlines - March 11, 2019 Category: Pathology Tags: Hematology-Oncology News Source Type: news

Shorter Stays After TAVR Associated With Better Outcomes Shorter Stays After TAVR Associated With Better Outcomes
Patients required to stay in hospital past 72 hours were at increased risk for adverse events after adjustment. In a second study, next-day discharge was shown to be safe in selected patients.Medscape Medical News (Source: Medscape Pathology Headlines)
Source: Medscape Pathology Headlines - March 7, 2019 Category: Pathology Tags: Cardiology News Source Type: news

Oral Health Status and Its Determinants Among Opiate Users Oral Health Status and Its Determinants Among Opiate Users
This study investigated the oral health status and its determinants among in-treatment opiate dependents.BMC Oral Health (Source: Medscape Pathology Headlines)
Source: Medscape Pathology Headlines - March 7, 2019 Category: Pathology Tags: Dental & Oral Health Journal Article Source Type: news

Explanted Mesh Doesn't Need Microscopic Assessment Explanted Mesh Doesn't Need Microscopic Assessment
There is no value to sending a mesh specimen for microscopic pathology evaluation, regardless of the reason for removal, nor can any clinical claims be made based on pathology findings from explanted mesh, researchers say.Reuters Health Information (Source: Medscape Pathology Headlines)
Source: Medscape Pathology Headlines - March 6, 2019 Category: Pathology Tags: General Surgery News Source Type: news

CHMP Backs Factor Xa Reversal Agent Andexanet (Ondexxya) CHMP Backs Factor Xa Reversal Agent Andexanet (Ondexxya)
Andexanet alfa, approved in the United States in 2018, would be the first drug approved for reversing major bleeds with the factor Xa inhibitors apixaban and rivaroxaban in Europe.International Approvals (Source: Medscape Pathology Headlines)
Source: Medscape Pathology Headlines - March 1, 2019 Category: Pathology Tags: Cardiology News Alert Source Type: news

' Blue' in Blueberries Tied to BP Lowering that Rivals Medication'Blue' in Blueberries Tied to BP Lowering that Rivals Medication
Eating the equivalent of 100 g of blueberries for 4 weeks twice a day is associated with systolic blood pressure lowering that is equal to the effect of BP-lowering medications, new research suggests.Medscape Medical News (Source: Medscape Pathology Headlines)
Source: Medscape Pathology Headlines - March 1, 2019 Category: Pathology Tags: Neurology & Neurosurgery News Source Type: news

Epidemic Group Invests $34 Mln in Potential Vaccine Printer Tech Epidemic Group Invests $34 Mln in Potential Vaccine Printer Tech
A coalition seeking to get ahead of the next pandemic has agreed a $34 million deal with German biotech CureVac to develop vaccine"printing" technology that aims to rapidly produce shots against multiple diseases.Reuters Health Information (Source: Medscape Pathology Headlines)
Source: Medscape Pathology Headlines - February 28, 2019 Category: Pathology Tags: Public Health & Prevention News Source Type: news

Wilson Disease: Overview Video Wilson Disease: Overview Video
This video covers the pathophysiology of Wilson disease, as well as common signs and symptoms, complications, and treatments.Osmosis (Source: Medscape Pathology Headlines)
Source: Medscape Pathology Headlines - February 28, 2019 Category: Pathology Tags: Med Students Commentary Source Type: news

Antiplatelets, Anticoagulants Similar After Cervical Dissection Antiplatelets, Anticoagulants Similar After Cervical Dissection
There was no difference in rates of stroke, residual stenosis, or occlusion at 1 year in patients treated with anticoagulants vs antiplatelet agents in the CADISS trial.Medscape Medical News (Source: Medscape Pathology Headlines)
Source: Medscape Pathology Headlines - February 28, 2019 Category: Pathology Tags: Neurology & Neurosurgery News Source Type: news

Patient Selection Key to DKA Prevention With SGLT Inhibitors in Type 1 Diabetes Patient Selection Key to DKA Prevention With SGLT Inhibitors in Type 1 Diabetes
Selection of appropriate patients for sodium-glucose cotransporter (SGLT)-inhibitor therapy is"critical" to minimizing the risk of diabetic ketoacidosis (DKA), an expert panel advises in a new consensus report.Reuters Health Information (Source: Medscape Pathology Headlines)
Source: Medscape Pathology Headlines - February 26, 2019 Category: Pathology Tags: Diabetes & Endocrinology News Source Type: news

Hypofractionated Radiotherapy Appropriate for Low-Risk Prostate Cancer Hypofractionated Radiotherapy Appropriate for Low-Risk Prostate Cancer
Hypofractionated radiotherapy (HRT) should be a new practice standard for men with low-risk prostate cancer, based on a secondary analysis of a phase III trial.Reuters Health Information (Source: Medscape Pathology Headlines)
Source: Medscape Pathology Headlines - February 26, 2019 Category: Pathology Tags: Hematology-Oncology News Source Type: news

High-Fat Diet Adversely Affects Gut Microbiota High-Fat Diet Adversely Affects Gut Microbiota
Higher-fat diets have unfavorable effects on gut microbiota, fecal metabolites and plasma proinflammatory factors, researchers from China report.Reuters Health Information (Source: Medscape Pathology Headlines)
Source: Medscape Pathology Headlines - February 25, 2019 Category: Pathology Tags: Gastroenterology News Source Type: news

Prediction Rule Identifies Febrile Infants at Low Risk for Serious Bacterial Infection Prediction Rule Identifies Febrile Infants at Low Risk for Serious Bacterial Infection
Researchers have developed and validated a clinical prediction rule that can help identify febrile infants age 60 days and younger who are at low risk for serious bacterial infection (SBI). The rule is based on urinalysis, absolute neutrophil count (ANC) and procalcitonin levels.Reuters Health Information (Source: Medscape Pathology Headlines)
Source: Medscape Pathology Headlines - February 22, 2019 Category: Pathology Tags: Pediatrics News Source Type: news

Expanding Genetic Testing for Prostate Cancer Could Improve Patient Management Expanding Genetic Testing for Prostate Cancer Could Improve Patient Management
Expanding genetic testing beyond current guidelines could better stratify prostate cancer patients for the presence of pathogenic variants and improve their medical management, researchers say.Reuters Health Information (Source: Medscape Pathology Headlines)
Source: Medscape Pathology Headlines - February 20, 2019 Category: Pathology Tags: Hematology-Oncology News Source Type: news

Paramedics Not Washing Their Hands Nearly Enough Paramedics Not Washing Their Hands Nearly Enough
Hand hygiene compliance among paramedics may be"remarkably low," according to a study that monitored ambulance workers in Scandinavia and Australia over six months.Reuters Health Information (Source: Medscape Pathology Headlines)
Source: Medscape Pathology Headlines - February 16, 2019 Category: Pathology Tags: Emergency Medicine News Source Type: news

Glottic Cancer Rates Rising in Young People Glottic Cancer Rates Rising in Young People
Glottic carcinoma rates in children and young adults have increased over the past three decades, according to a retrospective review.Reuters Health Information (Source: Medscape Pathology Headlines)
Source: Medscape Pathology Headlines - February 15, 2019 Category: Pathology Tags: Hematology-Oncology News Source Type: news

Mouse-Derived Kidneys Can Be Generated in Rats Mouse-Derived Kidneys Can Be Generated in Rats
Mouse pluripotent stem cells (PSCs) can differentiate into mouse-derived kidneys in anephric Sall1 mutant rats through interspecific blastocyst complementation, researchers from Japan report.Reuters Health Information (Source: Medscape Pathology Headlines)
Source: Medscape Pathology Headlines - February 14, 2019 Category: Pathology Tags: Pathology & Lab Medicine News Source Type: news

Minocycline Reduce Synaptic Pruning in Schizophrenia Cell Models Minocycline Reduce Synaptic Pruning in Schizophrenia Cell Models
Minocycline reduces excessive synaptic pruning in schizophrenia patient-derived cell models, suggesting that it might delay or prevent the onset of schizophrenia in some individuals, according to new research.Reuters Health Information (Source: Medscape Pathology Headlines)
Source: Medscape Pathology Headlines - February 13, 2019 Category: Pathology Tags: Psychiatry News Source Type: news

Solid Organ Donors and Screening Results for HBV, HBC, HIV Solid Organ Donors and Screening Results for HBV, HBC, HIV
How has the epidemic of opioid overdose deaths impacted risk for transmitting HIV and hepatitis viruses to solid organ recipients?Morbidity & Mortality Weekly Report (Source: Medscape Pathology Headlines)
Source: Medscape Pathology Headlines - February 13, 2019 Category: Pathology Tags: Public Health & Prevention Journal Article Source Type: news

Histological Subtype Best Outcome Predictor in Orbital Lymphoma Histological Subtype Best Outcome Predictor in Orbital Lymphoma
Reuters Health Information (Source: Medscape Pathology Headlines)
Source: Medscape Pathology Headlines - February 12, 2019 Category: Pathology Tags: Ophthalmology News Source Type: news

Pennsylvania Hospital Patient Tests Negative for Ebola Pennsylvania Hospital Patient Tests Negative for Ebola
An unidentified patient who was kept in isolation at a Philadelphia hospital while being tested for Ebola has been confirmed as not infected with the deadly virus, a hospital spokesman said on Wednesday.Reuters Health Information (Source: Medscape Pathology Headlines)
Source: Medscape Pathology Headlines - February 11, 2019 Category: Pathology Tags: Infectious Diseases News Source Type: news

Aspirin, Anticoagulants Up Rate of False Positives With FIT for Colorectal Cancer Aspirin, Anticoagulants Up Rate of False Positives With FIT for Colorectal Cancer
Regular use of aspirin or anticoagulants reduces the positive predictive value (PPV) of fecal immunochemical testing (FIT) for detecting colorectal cancer and advanced adenomas, researchers from Norway report.Reuters Health Information (Source: Medscape Pathology Headlines)
Source: Medscape Pathology Headlines - February 11, 2019 Category: Pathology Tags: Gastroenterology News Source Type: news

Collagen Signature Helps Predict Lymph-Node Metastasis in Gastric Cancer Collagen Signature Helps Predict Lymph-Node Metastasis in Gastric Cancer
In patients with early gastric cancer the collagen signature in the tumor microenvironment is an independent indicator of lymph-node metastasis, according to Chinese researchers.Reuters Health Information (Source: Medscape Pathology Headlines)
Source: Medscape Pathology Headlines - February 11, 2019 Category: Pathology Tags: Hematology-Oncology News Source Type: news

Recurrence Risk Constant After Ablation in Barrett's Esophagus Recurrence Risk Constant After Ablation in Barrett's Esophagus
Diligent surveillance remains important after remission of intestinal metaplasia (CRIM) following radiofrequency ablation (RFA) in Barrett's esophagus, researchers say.Reuters Health Information (Source: Medscape Pathology Headlines)
Source: Medscape Pathology Headlines - February 8, 2019 Category: Pathology Tags: Gastroenterology News Source Type: news

Thyroid Cancer Concerns No Greater With Active Surveillance Thyroid Cancer Concerns No Greater With Active Surveillance
Patients with low-risk thyroid cancers who chose active surveillance have similar worries to those who opt for surgery, but most ultimately express satisfaction with their choice of watchful waiting.Medscape Medical News (Source: Medscape Pathology Headlines)
Source: Medscape Pathology Headlines - February 4, 2019 Category: Pathology Tags: Diabetes & Endocrinology News Source Type: news

Identification of HER2 IHC-Negative, FISH+ Breast Cancers Identification of HER2 IHC-Negative, FISH+ Breast Cancers
Both immunohistochemistry for protein expression or fluorescent in situ hybridization for gene amplification can be used to determine HER2 status in breast cancer--but what if they don't agree?American Journal of Clinical Pathology (Source: Medscape Pathology Headlines)
Source: Medscape Pathology Headlines - February 4, 2019 Category: Pathology Tags: Pathology & Lab Medicine Journal Article Source Type: news

Thyroid Cancer in 2019: Questions That Remain Unanswered Thyroid Cancer in 2019: Questions That Remain Unanswered
What used to be a relatively rare malignancy, thyroid cancer diagnoses are now rising quickly. Dr Leung discusses what we currently know and some of the top questions that remain unanswered.Medscape Diabetes & Endocrinology (Source: Medscape Pathology Headlines)
Source: Medscape Pathology Headlines - January 28, 2019 Category: Pathology Tags: Diabetes & Endocrinology Article Source Type: news

New Genetic Risk Score May Help Detect Type 1 Diabetes New Genetic Risk Score May Help Detect Type 1 Diabetes
Potential clinical uses include cost-effective newborn screening and discrimination between diabetes types among newly diagnosed adults; the test is almost ready for prime time, says one researcher.Medscape Medical News (Source: Medscape Pathology Headlines)
Source: Medscape Pathology Headlines - January 23, 2019 Category: Pathology Tags: Diabetes & Endocrinology News Source Type: news

Microbiome Analysis Powers Insights to Improve Sleep Microbiome Analysis Powers Insights to Improve Sleep
New technologies can help identify poor sleep patterns and help physicians and patients find solutions, such as making changes to alter the microbiome.Medscape Medical News (Source: Medscape Pathology Headlines)
Source: Medscape Pathology Headlines - January 21, 2019 Category: Pathology Tags: Family Medicine/Primary Care News Source Type: news

Fish Oil, Particularly EPA, Linked to Reduced Ischemic Stroke Fish Oil, Particularly EPA, Linked to Reduced Ischemic Stroke
A new study of fish oils and ischemic stroke that included data on adipose tissue levels of key fatty acids has suggested a greater benefit with dietary intakes of EPA than with DHA or total fish oil.Medscape Medical News (Source: Medscape Pathology Headlines)
Source: Medscape Pathology Headlines - January 17, 2019 Category: Pathology Tags: Neurology & Neurosurgery News Source Type: news

Advanced Endoscopic Techniques Improve IBD Assessment Advanced Endoscopic Techniques Improve IBD Assessment
Advanced endoscopic techniques allow for better assessment of mucosal healing and dysplasia in patients with inflammatory bowel disease (IBD), according to a new review.Reuters Health Information (Source: Medscape Pathology Headlines)
Source: Medscape Pathology Headlines - January 10, 2019 Category: Pathology Tags: Gastroenterology News Source Type: news

Genomic Sequencing Detects Risks in Seemingly Healthy Newborns Genomic Sequencing Detects Risks in Seemingly Healthy Newborns
Newborn genomic sequencing (nGS) can identify risk and carrier status for a wide range of conditions not detectable by currently available newborn screening assays or predicted based on an infant's clinical or family history, researchers say.Reuters Health Information (Source: Medscape Pathology Headlines)
Source: Medscape Pathology Headlines - January 9, 2019 Category: Pathology Tags: Pediatrics News Source Type: news

Cord Blood Test May Flag Neonatal Hypoxia Risk Cord Blood Test May Flag Neonatal Hypoxia Risk
Umbilical cord blood microRNA may aid in the detection of impending hypoxic-ischemic brain injury in newborns, new research suggests.Medscape Medical News (Source: Medscape Pathology Headlines)
Source: Medscape Pathology Headlines - January 8, 2019 Category: Pathology Tags: Neurology & Neurosurgery News Source Type: news

Thyroid Nodule Size Irrelevant When It Comes to Malignancy Thyroid Nodule Size Irrelevant When It Comes to Malignancy
A meta-analysis shows no significant differences in malignancy or false-negative rates in small versus large thyroid nodules.Medscape Medical News (Source: Medscape Pathology Headlines)
Source: Medscape Pathology Headlines - January 2, 2019 Category: Pathology Tags: Diabetes & Endocrinology News Source Type: news

How a Cancer Doctor Really Feels About Second Opinions How a Cancer Doctor Really Feels About Second Opinions
Private-practice radiation oncologist Andrew Neuschatz talks about the nuances of second opinions in oncology.Medscape Oncology (Source: Medscape Pathology Headlines)
Source: Medscape Pathology Headlines - December 31, 2018 Category: Pathology Tags: Hematology-Oncology Commentary Source Type: news

New Breast-Imaging Technique May Reduce Unnecessary Biopsies New Breast-Imaging Technique May Reduce Unnecessary Biopsies
A new breast-image analysis technique may help reduce unnecessary breast biopsies, costs and patient anxiety, a new study suggests.Reuters Health Information (Source: Medscape Pathology Headlines)
Source: Medscape Pathology Headlines - December 18, 2018 Category: Pathology Tags: Hematology-Oncology News Source Type: news

Saliva Testing Accurately Identifies Children With Autism Saliva Testing Accurately Identifies Children With Autism
A salivary test based on multiple RNA features can accurately identify children with autism spectrum disorder (ASD), researchers report.Reuters Health Information (Source: Medscape Pathology Headlines)
Source: Medscape Pathology Headlines - December 18, 2018 Category: Pathology Tags: Pediatrics News Source Type: news

High-Performing Centenarians Have Increased T Cell Telomere Length and Telomerase Activity High-Performing Centenarians Have Increased T Cell Telomere Length and Telomerase Activity
Telomere length and telomerase activity following stimulation are greater in T cells of high-performing centenarians than in low-performing centenarians, researchers report.Reuters Health Information (Source: Medscape Pathology Headlines)
Source: Medscape Pathology Headlines - December 12, 2018 Category: Pathology Tags: Family Medicine/Primary Care News Source Type: news

Chemicals in Cosmetics, Soaps Tied to Early Puberty in Girls Chemicals in Cosmetics, Soaps Tied to Early Puberty in Girls
Girls who are exposed before birth to chemicals commonly found in toothpaste, makeup, soap and other personal care products may hit puberty earlier than their peers who aren't exposed to these chemicals in the womb, a U.S. study suggests.Reuters Health Information (Source: Medscape Pathology Headlines)
Source: Medscape Pathology Headlines - December 7, 2018 Category: Pathology Tags: Ob/Gyn & Women ' s Health News Source Type: news

Hypertonic-Saline Inhalation Boosts Lung Function in Infants With Cystic Fibrosis Hypertonic-Saline Inhalation Boosts Lung Function in Infants With Cystic Fibrosis
Inhalation of hypertonic saline improves lung function and growth in infants with cystic fibrosis (CF), according to the results of the PRESIS randomized controlled trial.Reuters Health Information (Source: Medscape Pathology Headlines)
Source: Medscape Pathology Headlines - December 7, 2018 Category: Pathology Tags: Pulmonary Medicine News Source Type: news

WHO Looks at Standards in & quot;Uncharted Water & quot; of Gene Editing WHO Looks at Standards in & quot;Uncharted Water & quot; of Gene Editing
The World Health Organization (WHO) warned on Monday that gene editing may have"unintended consequences" and said it was establishing a team of experts to set clear guidelines and standards after studying ethical and safety issues.Reuters Health Information (Source: Medscape Pathology Headlines)
Source: Medscape Pathology Headlines - December 6, 2018 Category: Pathology Tags: Internal Medicine News Source Type: news

Blood and Ileal T Cell Expression Profiles Differ in Crohn's Disease Blood and Ileal T Cell Expression Profiles Differ in Crohn's Disease
T cells in peripheral blood and ileal biopsies show markedly different expression profiles in patients with Crohn's disease (CD), researchers report.Reuters Health Information (Source: Medscape Pathology Headlines)
Source: Medscape Pathology Headlines - December 6, 2018 Category: Pathology Tags: Gastroenterology News Source Type: news

TNBC Study of Capecitabine Mostly Disappoints, With One Exception TNBC Study of Capecitabine Mostly Disappoints, With One Exception
A study of adjuvant capecitabine in triple-negative breast cancer was largely negative, but disease-free and overall survival were improved in a subset of patients with the nonbasal-like phenotype.Medscape Medical News (Source: Medscape Pathology Headlines)
Source: Medscape Pathology Headlines - December 6, 2018 Category: Pathology Tags: Hematology-Oncology News Source Type: news