Key to regulating cell's powerhouse discovered
Aging, neurodegenerative disorders and metabolic disease are all linked to mitochondria, structures within our cells that generate chemical energy and maintain their own DNA. In a fundamental discovery with far-reaching implications, scientists now show how cells control DNA synthesis in mitochondria and couple it to mitochondrial division. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - July 15, 2016 Category: Science Source Type: news

Key to regulating cell's powerhouse discovered
(University of California - Davis) Aging, neurodegenerative disorders and metabolic disease are all linked to mitochondria, structures within our cells that generate chemical energy and maintain their own DNA. In a fundamental discovery with far-reaching implications, scientists at UC Davis now show how cells control DNA synthesis in mitochondria and couple it to mitochondrial division. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 14, 2016 Category: Global & Universal Source Type: news

Selfish mitochondria implicated in a variety of diseases
A research team has identified some of the methods that allow mutant mitochondrial DNA to act selfishly by circumventing the molecular mechanisms that cells use to regulate mitochondrial activity. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - July 12, 2016 Category: Science Source Type: news

Emerging Therapies for Mitochondrial DisordersEmerging Therapies for Mitochondrial Disorders
Several new approaches are currently under investigation for the treatment of mitochondrial diseases, on both the molecular and cellular level. Which hold the most promise? Brain (Source: Medscape Allergy Headlines)
Source: Medscape Allergy Headlines - July 12, 2016 Category: Allergy & Immunology Tags: Neurology & Neurosurgery Journal Article Source Type: news

Selfish mitochondria implicated in a variety of diseases
(Vanderbilt University) A Vanderbilt research team has identified some of the methods that allow mutant mitochondrial DNA to act selfishly by circumventing the molecular mechanisms that cells use to regulate mitochondrial activity. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - July 12, 2016 Category: Infectious Diseases Source Type: news

New rapid gene test for mitochondrial disease
A genetic test has been developed, providing a rapid diagnosis of mitochondrial disorders to identify the first patients with inherited mutations in a new disease gene. The team of medics and scientists working on the study have identified mutations in a gene, known as TMEM126B, involved in energy production in patient's muscles. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - July 7, 2016 Category: Science Source Type: news

Cloning for Medicine: the Miracle that Wasn’t
By Editor, Sunday Times, Sri LankaJul 5 2016 (The Sunday Times - Sri Lanka)PARIS, AFP – When Dolly the cloned sheep was born 20 years ago on July 5, many hailed mankind’s new-found mastery over DNA as a harbinger of medical miracles such as lab-grown transplant organs. Others trembled at the portent of a “Brave New World” of identical humans farmed for spare parts or as cannon fodder.As it turns out, neither came to pass.Human cloning — complicated, risky and ethically contentious — has largely been replaced as the holy grail of regenerative medicine by other technologies, say experts.“It has ...
Source: IPS Inter Press Service - Health - July 5, 2016 Category: Global & Universal Authors: Editor Sunday Times Tags: Development & Aid Global Headlines Health Source Type: news

Cloning for Medicine: the Miracle that Wasn ’ t
By Editor, Sunday Times, Sri LankaJul 5 2016 (The Sunday Times - Sri Lanka)PARIS, AFP – When Dolly the cloned sheep was born 20 years ago on July 5, many hailed mankind’s new-found mastery over DNA as a harbinger of medical miracles such as lab-grown transplant organs. Others trembled at the portent of a “Brave New World” of identical humans farmed for spare parts or as cannon fodder.As it turns out, neither came to pass.Human cloning — complicated, risky and ethically contentious — has largely been replaced as the holy grail of regenerative medicine by other technologies, say experts.“It has ...
Source: IPS Inter Press Service - Health - July 5, 2016 Category: Global & Universal Authors: Editor Sunday Times Tags: Development & Aid Global Headlines Health Source Type: news

MENDing The Alzheimer's Brain
Alzheimer's Disease is a degenerative disease of the brain that is currently thought to affect nearly 44 million people in the world. In the United States alone, over 5 million people suffer the illness. It is estimated that, at current rates, that number will grow to more than 17 million by 2050. It is an expensive illness. The Alzheimer's Association predicts that the disease will cost our country 236 billion dollars in 2016. However, the human cost of the illness is incalculable. Despite the efforts of many, there has been no cure for the disease. At present, no one medication works to either prevent it or substanti...
Source: Healthy Living - The Huffington Post - June 30, 2016 Category: Consumer Health News Source Type: news

Persian Gulf War Veterans Still Suffering Serious Health Problems
This year marks the 25th anniversary of the Persian Gulf War. It was fought in late 1990 through early 1991 by a U.S.-led coalition of 34 countries against Iraq in response to Saddam Hussein's invasion of Kuwait. It also was the first U.S. war to be waged after the advent of the 24-hour cable television news cycle. The conflict was accompanied by memorably intense and round-the-clock coverage on CNN. But there've been few recognitions of the war's 25-year milestone on the cable news networks, let alone in broadcast or print media. For David Winnett, a Gulf War combat veteran who climbed the ranks from private to capta...
Source: Healthy Living - The Huffington Post - June 21, 2016 Category: Consumer Health News Source Type: news

Long Distance Running Effects On Your Health
Long distance running is becoming more and more popular. Close to two million people every year drag themselves across the finish lines. And that’s just in half marathon races. Runners in these 13.1 mile events have increased six-fold over the past 25 years.  All these amateur athletes think they’re getting really healthy as they work themselves up to full marathons. But the truth is they are cutting years off their life.  You can see it for yourself if you stand at the finish line of any race. The hardcore runners look terrible. They look gaunt and malnourished. They are hunched over and have a stif...
Source: Al Sears, MD Natural Remedies - June 20, 2016 Category: Complementary Medicine Authors: Al Sears Tags: Fitness Source Type: news

Birthday honours: Mitochondrial disease doctor recognised
The doctor behind a groundbreaking IVF technique which prevents disabling genetic disorders from being passed on to future generations is knighted in the Queen's Birthday Honours list. (Source: BBC News | Health | UK Edition)
Source: BBC News | Health | UK Edition - June 10, 2016 Category: Consumer Health News Source Type: news

New safety and efficacy evidence for mitochondrial donation revealed
(Wellcome Trust) A new IVF-based technique is likely to lead to normal pregnancies and reduce the risk that babies born will have mitochondrial disease, according to researchers at the Wellcome Trust Centre for Mitochondrial Disease at Newcastle University. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - June 8, 2016 Category: Global & Universal Source Type: news

Mobilizing mitochondria may be key to regenerating damaged neurons
(Rockefeller University Press) Researchers at the National Institute of Neurological Disorders and Stroke have discovered that boosting the transport of mitochondria along neuronal axons enhances the ability of mouse nerve cells to repair themselves after injury. The study, 'Facilitation of axon regeneration by enhancing mitochondrial transport and rescuing energy deficits,' which has been published in The Journal of Cell Biology, suggests potential new strategies to stimulate the regrowth of human neurons damaged by injury or disease. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 7, 2016 Category: Global & Universal Source Type: news

[Perspective] The cancer predisposition revolution
Studies of rare cancer predisposition syndromes often lead to the identification of genes critical to carcinogenesis. In 1969, Li and Fraumeni described a constellation of various cancers in the family members of four unrelated children who were diagnosed with soft tissue sarcomas (1). They posited that the cancers best fit an autosomal dominant pattern of inheritance, attributable to a genetic defect. At that time, cancer was not generally thought of as a genetic disease. Their hypothesis set the stage for establishing germline mutations in the tumor suppressor gene TP53 as the underlying genetic event in Li-Fraumeni synd...
Source: ScienceNOW - May 26, 2016 Category: Science Authors: David Malkin Tags: Cancer Source Type: news