Mitochondrial disease has a disproportionate healthcare burden in US
(Children's Hospital of Philadelphia) Mitochondrial diseases are a diverse group of disorders caused by mutated genes that impair energy production in a patient's cells, often with severe effects. Patients with these diseases incur high medical costs for hospitalization, and suffer higher-than-typical rates of comorbid diseases and in-hospital mortality. Researchers who analyzed those costs say their findings underscore the importance of developing preventive strategies and therapies for these illnesses. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 28, 2017 Category: International Medicine & Public Health Source Type: news
Mitoconix Bio Raises $20 Million in Series A Funding to Develop Neurodegenerative Disease Therapies
Proceeds will be used to advance the Company's lead product through preclinical and clinical development and expand its therapeutic pipeline for treating neurodegenerative disorders by improving mitochondrial function
NESS ZIONA, Israel, June 27, 2017 -... Biopharmaceuticals, Neurology, Venture Capital Mitoconix Bio, Huntington's disease (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - June 27, 2017 Category: Pharmaceuticals Source Type: news
How to Protect Your Brain Against Alzheimer ’s
A few weeks ago, Big Pharma giant Merck canceled the clinical trial for its latest “promising” Alzheimer’s drug.
Why?
It was a total flop.
The same thing happened four months ago with a drug that Eli Lilly was testing.
The reality is that more than 99% of Alzheimer’s drugs fail in development. This proves that mainstream medicine has no clue what causes this brain-wasting condition.
So what’s really going on?
A big part of the problem is in the very air we breathe. And the closer you live to a major roadway or urban center, the worse it is…
...
Source: Al Sears, MD Natural Remedies - June 22, 2017 Category: Complementary Medicine Authors: Cathy Card Tags: Brain Health Nutrition Alzheimer's cognitive decline pollution toxins Source Type: news
6 Ways To Survive Summer Travel With A Chronic Illness
Two summers ago, I planned the family road trip of a lifetime. I bought an inexpensive and used camping trailer, loaded it up with everything from toiletries to food, and set out on a 21-day road trip through six western states. I planned our route meticulously, lining up activities and stops along the way, but what got lost in the shuffle was my own chronic health needs.
I assumed I would be able to stretch out my regular medical infusions to allow for my travel or refill my prescriptions on-the-go, but I quickly learned how wrong I was. I spent way too much of my vacation tackling my medical challenges instead of enjoyin...
Source: Healthy Living - The Huffington Post - June 14, 2017 Category: Consumer Health News Source Type: news
Aberrant telomere length and mitochondrial DNA copy number in suicide completers - Otsuka I, Izumi T, Boku S, Kimura A, Zhang Y, Mouri K, Okazaki S, Shiroiwa K, Takahashi M, Ueno Y, Shirakawa O, Sora I, Hishimoto A.
Short telomere length (TL) occurs in individuals under psychological stress, and with various psychiatric diseases. Recent studies have also reported mitochondrial DNA copy number (mtDNAcn) alterations under several neuropsychiatric conditions. However, no... (Source: SafetyLit)
Source: SafetyLit - June 14, 2017 Category: International Medicine & Public Health Tags: Ergonomics, Human Factors, Anthropometrics, Physiology Source Type: news
Potential therapeutic target for Parkinson's disease
Investigations by scientists in Japan illustrate how the loss of a key mitochondrial protein facilitates the progression of Parkinson's disease. The findings are published in Nature Communications. (Source: Parkinson's Disease News From Medical News Today)
Source: Parkinson's Disease News From Medical News Today - June 13, 2017 Category: Neurology Tags: Parkinson's Disease Source Type: news
Neurodegenerative disease mechanism and potential drug identified
(University of California - Davis) Two new, UC Davis-led studies of neurodegenerative diseases linked to mitochondrial defects offer hope for developing a new biomarker for research and diagnostics, and a drug for treating such diseases. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 6, 2017 Category: International Medicine & Public Health Source Type: news
Disease Awareness Months Work, Even If You Don't Wear The Ribbon
June is the month for more than 10 disease-related awareness campaigns, including Myasthenia Gravis Awareness Month, National Congenital Cytomegalovirus Awareness Month and National Scleroderma Awareness Month. It also hosts a handful of awareness weeks and days, ranging from Helen Keller Deaf-Blind Awareness Week to World Sickle Cell Day.
June’s awareness list is shorter than most, but every month is full of diseases and disorders to take note of. You probably haven’t heard of half of them, and you’re not alone. So what’s the point of an awareness day, week or month?
To understand the chall...
Source: Healthy Living - The Huffington Post - June 2, 2017 Category: Consumer Health News Source Type: news
Parents of sick baby say therapy in US is son's 'last hope' of survival
Chris Gard and Connie Yates want appeal court judges to overrule earlier decision for hospital to withdraw Charlie ’s life supportA couple who want to take their sick baby son abroad for treatment have asked three court of appeal judges not to take away their “only remaining hope” for his survival.Chris Gard and Connie Yates want permission to take nine-month-old Charlie, who has a form of mitochondrial disease that causes brain damage and muscle problems, to the US for a therapy trial.Continue reading... (Source: Guardian Unlimited Science)
Source: Guardian Unlimited Science - May 23, 2017 Category: Science Authors: Press Association Tags: Court of appeal UK news Neuroscience US healthcare NHS Hospitals Genetics Biology US news Law London Source Type: news
Family history of Alzheimer's may alter metabolic gene that increases risk for disease
(Iowa State University) A new Iowa State University study may have identified the link that explains years of conflicting research over a mitochondrial gene and the risk for Alzheimer's disease. Researchers found a dramatic difference in the gene's impact on memory, general cognitive function and risk based on a family history of Alzheimer's disease and the length of a specific section of the gene. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - May 23, 2017 Category: International Medicine & Public Health Source Type: news
Low oxygen reverses mitochondrial disease in mice
Hypoxia reverses brain damage caused by mitochondrial dysfunction, a team finds. The approach might one day point to new therapies for people with Leigh syndrome and other mitochondrial disorders. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - May 8, 2017 Category: Science Source Type: news
KU Med researchers test new approach to Alzheimer's
The Kansas City Area Life Sciences Institute Inc. re-launched its Collaborate2Cure series on Monday, with two speakers sharing new approaches to treating Alzheimer's disease. In the coming months, area researchers will present on the topic of mitochondrial dysfunction, with the potential to land a $50,000 grant for collaborative research.
The free weekly seminars take place 4 to 6 p.m. every Monday at the University of Kansas Medical Center's Research Institute in Fairway. Registration and archived… (Source: bizjournals.com Health Care:Biotechnology headlines)
Source: bizjournals.com Health Care:Biotechnology headlines - May 2, 2017 Category: Biotechnology Authors: Elise Reuter Source Type: news
KU Med researchers test new approach to Alzheimer's
The Kansas City Area Life Sciences Institute Inc. re-launched its Collaborate2Cure series on Monday, with two speakers sharing new approaches to treating Alzheimer's disease. In the coming months, area researchers will present on the topic of mitochondrial dysfunction, with the potential to land a $50,000 grant for collaborative research.
The free weekly seminars take place 4 to 6 p.m. every Monday at the University of Kansas Medical Center's Research Institute in Fairway. Registration and archived… (Source: bizjournals.com Health Care:Pharmaceuticals headlines)
Source: bizjournals.com Health Care:Pharmaceuticals headlines - May 2, 2017 Category: Pharmaceuticals Authors: Elise Reuter Source Type: news
Unravelling the mystery of DNA attacks in cells' powerhouse could pave way for new cancer treatments
A five-year study has found the mechanism responsible for repairing damage to mitochondrial DNA. This discovery could pave the way for new treatments for cancer and neurodegenerative diseases, say the researchers. This research may also have important implications for clinical advances in so called ‘three-parent baby’ mitochondrial donation. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - April 28, 2017 Category: Science Source Type: news
Vital role for mitochondrial calcium exchange in heart function
Scientists have long thought that calcium transport into mitochondria is a key signal linking cardiac workload, or how hard the heart pumps, with energy production. Now, in a major breakthrough, researchers show that the exit of calcium from mitochondria serves a critical role in heart function and may represent a powerful therapeutic approach to limit heart disease. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - April 26, 2017 Category: Science Source Type: news
