Peninsula biotech sheds 20% of jobs to focus on drugs closer to finish line
Cancer-fighting Five Prime Therapeutics Inc. will cut about 20 percent of its 209-person workforce as it tries to push more drugs into clinical trials and advance those already being tested on patients. The move — the first large-scale layoff in the South San Francisco biotech company's 17 years — comes during a sustained push by Five Prime (NASDAQ: FPRX) into cancer immunotherapy, where drugs are used to rally the immune system to battle cancer. The job cuts, starting today, include researc h,… (Source: bizjournals.com Health Care:Pharmaceuticals headlines)
Source: bizjournals.com Health Care:Pharmaceuticals headlines - January 15, 2019 Category: Pharmaceuticals Authors: Ron Leuty Source Type: news

MobileODT touts colposcope-based cervical cancer detection AI
MobileODT said last week that it is implementing a new artificial intelligence algorithm in its EVA system Colposcope that it claims can detect cervical cancer more effectively than existing testing. The new technology, known as Automated Visual Evaluation, has been validated by the National Cancer Institute and the National Library of Medicine, the Israel-based company said, and is able to identify problematic lesions with greater reliability than traditional Pap Cytology testing. MobileODT said that it is working with the NCI and other researchers to continue validating the AVE algorithm, and that it is launching a ...
Source: Mass Device - January 15, 2019 Category: Medical Devices Authors: Fink Densford Tags: Imaging Software / IT Women's Health mobileodt Source Type: news

City recognizes Philly Fights Cancer for impact on medical research
Mayor Jim Kenney recognized Monday Philly Fights Cancer, the main fundraising channel of Penn Medicine ’s Abramson Cancer Center, for its multi-million dollar efforts to support research at the center with an official city citation. "These institutions are taking on some of the most difficult medical challenges facing the globe," Kenney said. "Philly Fights Cancer and Penn Medicine’s Abramson C ancer Center especially have demonstrated tremendous leadership in the battle to end cancer once and… (Source: bizjournals.com Health Care:Pharmaceuticals headlines)
Source: bizjournals.com Health Care:Pharmaceuticals headlines - January 15, 2019 Category: Pharmaceuticals Authors: HughE Dillon, Alison Burdo Source Type: news

More doctors, white people in region linked to lower skin cancer survival
A person's race and location play a big role in whether they will survive skin cancer, a new study suggests. (Source: Health News - UPI.com)
Source: Health News - UPI.com - January 15, 2019 Category: Consumer Health News Source Type: news

Surgery/HIPEC Safer Than Other High-Risk Cancer Procedures
(MedPage Today) -- Lower infection, 30-day mortality rates than with Whipple, esophagectomy (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - January 15, 2019 Category: Hematology Source Type: news

ICYMI: New study reinforces dangers of proposed IPI model
Stakeholder after stakeholder has raised concerns that the Department of Health and Human Services ’ proposed International Pricing Index (IPI) Model would put patient access to medicines in Medicare Part B at risk – medicines that are necessary to treat complex conditions like cancer, rheumatoid arthritis and autoimmune diseases. One of the most common concerns is that patients in the United States will experience the same access restrictions that patients face abroad if the U.S. government proceeds with copying the flawed pricing practices of foreign governments. Recently,IHS Markit released a study that show...
Source: The Catalyst - January 15, 2019 Category: Pharmaceuticals Tags: Part B Access Medicare Source Type: news

Cancer symptoms: Six signs of the deadly disease you mustn’t ignore
CANCER symptoms can vary greatly, with some signs seeming obvious while others may seem harmless or be mistaken for other less serious conditions. Here are six signs of cancer you must not ignore. (Source: Daily Express - Health)
Source: Daily Express - Health - January 15, 2019 Category: Consumer Health News Source Type: news

Breast cancer cells could be stopped from spreading if they are turned into FAT cells instead
Cancer cells can spread and grow by transitioning into stem-like cells. During transition, scientists in Switzerland have been able to coax them into becoming fat cells. (Source: the Mail online | Health)
Source: the Mail online | Health - January 15, 2019 Category: Consumer Health News Source Type: news

Comorbidities Adversely Linked to Cancer Trial Participation
Reduction in trial discussions, trial offers, trial participation seen with one or more comorbidities (Source: The Doctors Lounge - Oncology)
Source: The Doctors Lounge - Oncology - January 15, 2019 Category: Cancer & Oncology Tags: Gastroenterology, Gynecology, Oncology, Pharmacy, Pulmonology, Urology, Journal, Source Type: news

US states with fewer cases of melanoma have HIGHER death rates from the cancer, study finds
A new study from the University of Utah Health has found that the states with the lowest incidence of melanoma, including Texas, Louisiana and Alabama, have the worst survival rates. (Source: the Mail online | Health)
Source: the Mail online | Health - January 15, 2019 Category: Consumer Health News Source Type: news

Medical News Today: Breast cancer: Changing tumor cells into fat cells stops spread
By exploiting cancer cells' innate adaptability, scientists halt invasive spread in mice by transforming malignant breast cancer cells into fat cells. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - January 15, 2019 Category: Consumer Health News Tags: Breast Cancer Source Type: news

New Tool Calculates Breast Cancer Risk With Greater Precision
(CNN) — UK scientists have developed an online calculator that could enable doctors to more accurately predict a patient’s chance of developing breast cancer. If rolled out, the new tool could change the way in which the condition is treated. Among other things, details of family history, genetics, weight, alcohol consumption, age at menopause and use of hormone replacement therapy will all be considered by doctors when assessing a woman’s risk of developing breast cancer — the most common form of cancer in the UK. Each of these factors has “a small impact on the likelihood of developing the d...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - January 15, 2019 Category: Consumer Health News Authors: Health – CBS Boston Tags: Health News Breast Cancer CNN Local TV Source Type: news

New tool calculates breast cancer risk with greater precision
UK scientists have developed an online calculator that could enable doctors to more accurately predict a patient's chance of developing breast cancer. (Source: CNN.com - Health)
Source: CNN.com - Health - January 15, 2019 Category: Consumer Health News Source Type: news

USPSTF Reaffirms Drugs for Women at High Risk for Breast Cancer USPSTF Reaffirms Drugs for Women at High Risk for Breast Cancer
In new draft guidelines, the US Preventive Services Task Force (USPSTF) continues to recommend the use of chemopreventive agents for women at high risk for breast cancer.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - January 15, 2019 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

Race May Matter for Liver Transplant Success
TUESDAY, Jan. 15, 2019 -- Black Americans who receive a liver transplant to treat liver cancer may survive much longer if the new organ comes from a black donor, a new study suggests. " Our data are intriguing. But our results require validation, " ... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - January 15, 2019 Category: General Medicine Source Type: news

How AI can detect cervical cancer
Cervical cancer cells (Image from National Cancer Institute\Winship Cancer Institute of Emory University) Researchers have developed a computer algorithm that they say can analyze digital images of a woman’s cervix and accurately identify precancerous changes that require medical attention. This artificial intelligence approach, called automated visual evaluation, has the potential to revolutionize cervical cancer screening, particularly in low-resource settings. Led by investigators from the National Institutes of Health and humanitarian tech investment fund Global Good, the researchers used comprehensive datas...
Source: Mass Device - January 15, 2019 Category: Medical Devices Authors: Nancy Crotti Tags: Big Data Blog Diagnostics Gynecological News Well Oncology Research & Development globalgood National Institutes of Health (NIH) nationalcancerinstitute Source Type: news

Two more diabetes drugs approved for use by NHS in Scotland
Two medicines for treating diabetes, along with one for advanced breast cancer, have been approved for use by the NHS in Scotland. (Source: Nursing Times)
Source: Nursing Times - January 15, 2019 Category: Nursing Source Type: news

Patient who shot GP with a crossbow over his father's death is guilty of attempted murder - Dyer C.
A patient who blamed his family GP for his father ’s death from lung cancer has been convicted of attempted murder after shooting the doctor with a crossbow. Mark Waterfall burst into GP Gary Griffith’s consulting room at the Suthergrey House Medi... (Source: SafetyLit)
Source: SafetyLit - January 15, 2019 Category: International Medicine & Public Health Tags: Commentary Source Type: news

High Fiber, Whole Grains Linked to CVD, Diabetes, Cancer Risk High Fiber, Whole Grains Linked to CVD, Diabetes, Cancer Risk
An ambitious review of 40 years of research commissioned by the WHO shows that higher intake of dietary fiber and whole grains is related to a'surprisingly broad'range of diseases.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - January 15, 2019 Category: Consumer Health News Tags: Cardiology News Source Type: news

Olympus inks precision cancer imaging and treatment dev deal with USC
Olympus (TYO:7733) said late last week that it inked a co-development partnership with the University of Southern California looking to advance multiscale research into cancer prevention, diagnosis and treatment through the use of precision medicine. The deal is a first for the university and the company, Olympus said, adding that it hopes that the personalized treatments that emerge from the partnership will advance cancer research and “potentially improve the precision of patient diagnosis and treatment.” “Olympus is honored to provide the optical tools used to capture the breadth of what’s h...
Source: Mass Device - January 15, 2019 Category: Medical Devices Authors: Fink Densford Tags: Business/Financial News Imaging Oncology Research & Development Olympus Source Type: news

How an East Bay cancer fighter — once kicked to the curb by Big Pharma — picked up its 4th drug approval
Even in the days after Bristol-Myers Squibb Co. threw an experimental cancer drug back to Exelixis Inc. nearly a decade ago, there were signs of hope: strong signals from a broad trial that tested the drug across nine tumor types. One of those signals was confirmed Monday as the Food and Drug Administration approved that drug — branded as Cabometyx — as one of a handful of options for people with the most common kind of liver cancer. It is the fourth FDA approval of "cabo" for Alameda-based… (Source: bizjournals.com Health Care:Biotechnology headlines)
Source: bizjournals.com Health Care:Biotechnology headlines - January 15, 2019 Category: Biotechnology Authors: Ron Leuty Source Type: news

Vaccine, Screening Can Prevent Cervical Cancer Deaths
TUESDAY, Jan. 15, 2019 -- About 4,000 women in the United States die from cervical cancer each year -- even though there's a preventive vaccine and screening to catch the disease early. " When cervical cancer is found early, it is highly treatable, " ... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - January 15, 2019 Category: General Medicine Source Type: news

Cervical Health Awareness Month
(Source: Karmanos Cancer Institute)
Source: Karmanos Cancer Institute - January 15, 2019 Category: Cancer & Oncology Source Type: news

Cabozantinib Wins OK for Advanced Liver Cancer
(MedPage Today) -- Pivotal trial showed 2.2-month survival improvement (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - January 15, 2019 Category: Hematology Source Type: news

The Demise Of A Once Promising Pancreatic Cancer Drug Is All Too Common
Companies as small as Nivien or as large as Pfizer find the chemical tools and run the experiments that prove or disprove medical hypotheses. (Source: Forbes.com Healthcare News)
Source: Forbes.com Healthcare News - January 15, 2019 Category: Pharmaceuticals Authors: John LaMattina, Contributor Tags: NYSE:PFE NYSE:MRK NYSE:LLY NYSE:NVS Source Type: news

Comorbidities Adversely Linked to Cancer Trial Participation
TUESDAY, Jan. 15, 2019 -- For cancer patients, the presence of comorbidities is adversely linked to trial discussions, trial offers, and trial participation, according to a study published online Jan. 10 in JAMA Oncology. Joseph M. Unger, Ph.D.,... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - January 15, 2019 Category: Pharmaceuticals Source Type: news

Diabetes drug may help to treat breast cancer
Research, published inCancer Cell, suggests that the diabetes drug rosiglitazone, combined with trametinib, could treat breast cancer by turning cancerous cells into fat cells. Science Alert (Source: Society for Endocrinology)
Source: Society for Endocrinology - January 15, 2019 Category: Endocrinology Source Type: news

Cabozantinib Now Also FDA Approved for Liver Cancer Cabozantinib Now Also FDA Approved for Liver Cancer
A new indication allows cabozantinib to be used in patients with hepatocellular carcinoma who have previously been treated with sorafenib.FDA Approvals (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - January 15, 2019 Category: Cancer & Oncology Tags: Hematology-Oncology News Alert Source Type: news

Stop smoking: How to more than DOUBLE your chance of success - Dr Chris reveals
STOP smoking: Quitting smoking has a number of health benefits, including lowering your risk of cancer, as well as making you feel less tired. But what ’s the best way to give up cigarettes? ITV This Morning’s Dr Chris reveals how to double your chance of success. (Source: Daily Express - Health)
Source: Daily Express - Health - January 15, 2019 Category: Consumer Health News Source Type: news

Becca Henderson: Transplant hope for rucksack heart woman
Scans show Becca Henderson has been clear of cancer for a year and is now eligible for a donor heart. (Source: BBC News | Health | UK Edition)
Source: BBC News | Health | UK Edition - January 15, 2019 Category: Consumer Health News Source Type: news

Rebecca Henderson: Transplant hope for rucksack heart woman
Scans show Rebecca Henderson has been clear of cancer for a year and is now eligible for a donor heart. (Source: BBC News | Health | UK Edition)
Source: BBC News | Health | UK Edition - January 15, 2019 Category: Consumer Health News Source Type: news

Breast cancer risk test 'game changer'
GPs would use the online calculator to tell women their risk of getting breast cancer, say scientists. (Source: BBC News | Health | UK Edition)
Source: BBC News | Health | UK Edition - January 15, 2019 Category: Consumer Health News Source Type: news

Muscle stem cells can drive cancer that arises in Duchenne muscular dystrophy
People with Duchenne muscular dystrophy (DMD) can develop an otherwise-rare muscle cancer, called rhabdomyosarcoma, due to the muscle cells' continuous work to rebuild the damaged tissue. However, little is known about how the cancer arises, hindering development of a treatment or test that could predict cancer risk. (Source: World Pharma News)
Source: World Pharma News - January 15, 2019 Category: Pharmaceuticals Tags: Featured Research Research and Development Source Type: news

Less jargon makes MRI reports easier to read
It's time for radiologists to use more common words that patients can understand...Read more on AuntMinnie.comRelated Reading: How patient consumerism affects today's radiology practice Lung cancer patient education materials are inadequate Online patient info about UAE could be better New program helps radiologists come out of the dark Yelp reveals what patients value about imaging services (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - January 15, 2019 Category: Radiology Source Type: news

GPs could use breast cancer 'calculator' to predict risk to women
Scientists devise method using genetic data and lifestyle to work out who should be screenedWomen may be able to go to their GP to find out their risk of getting breast cancer and choose whether or not to be screened, if a new online calculator devised by scientists is successful.Related:Women with BRCA gene mutations given clearer picture of breast and ovarian cancer riskContinue reading... (Source: Guardian Unlimited Science)
Source: Guardian Unlimited Science - January 15, 2019 Category: Science Authors: Sarah Boseley Health editor Tags: Cancer research Breast cancer Science Women UK news Health Source Type: news

Antihypertension drug losartan may improve treatment of ovarian cancer
(Massachusetts General Hospital) A new study from a Massachusetts General Hospital research team has found that the hypertension drug losartan, which targets the angiotensin signaling pathway, may improve the effectiveness of chemotherapy agents used to treat ovarian cancer. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - January 15, 2019 Category: Cancer & Oncology Source Type: news

Scientists identify gene contributing to prostate cancer drug resistance
(eLife) Researchers have discovered how a gene involved in regulating hormone receptors may contribute to drug resistance in some prostate cancer patients. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - January 15, 2019 Category: Cancer & Oncology Source Type: news

Muscle stem cells can drive cancer that arises in Duchenne muscular dystrophy
(Sanford Burnham Prebys Medical Discovery Institute) Scientists from Sanford Burnham Prebys Medical Discovery Institute (SBP) have demonstrated that muscle stem cells may give rise to rhabdomyosarcoma that occurs during DMD--and identified two genes linked to the tumor's growth. The research, performed using a mouse model of severe DMD, helps scientists better understand how rhabdomyosarcoma develops in DMD--and indicates that ongoing efforts to develop treatments that stimulate muscle stem cells should consider potential cancer risk. The study was published in Cell Reports on January 15, 2019. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - January 15, 2019 Category: Cancer & Oncology Source Type: news

Purchase receipts with easily erasable ink contain cancer-infertility inducing substances
(University of Granada) An international research led by the UGR shows that 90 percent of store and supermarket receipts are made of thermal paper containing bisphenol A (BPA). (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - January 15, 2019 Category: Cancer & Oncology Source Type: news

EU and Canada award € 8.65 million to project to ease genomic and health data sharing
(Bar-Ilan University) The European Union (EU) and the Canadian government have awarded the international iReceptor Plus consortium € 8.65 million to promote human immunological data storage, integration and controlled sharing for a wide range of clinical and scientific purposes. The four-year project aims to develop an innovative platform to integrate distributed repositories of Adaptive Immune Receptor Repertoire sequencing (AIRR-seq) data for enabling improved personalized medicine and immunotherapy in cancer, inflammatory and autoimmune diseases, allergies and infectious diseases. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - January 15, 2019 Category: Cancer & Oncology Source Type: news

MD Anderson Cancer Center and Dragonfly Therapeutics announce strategic collaboration to take new immunotherapy candidates into clinical trials
(University of Texas M. D. Anderson Cancer Center) The University of Texas MD Anderson Cancer Center and Dragonfly Therapeutics Inc. today announced a strategic collaboration to bring Dragonfly's TriNKET ™ (tri-specific natural killer cell engager therapy) immunotherapy drug candidates to patients in clinical trials beginning in 2019. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - January 15, 2019 Category: Cancer & Oncology Source Type: news

Gene-editing tool CRISPR/Cas9 shown to limit impact of certain parasitic diseases
(George Washington University) For the first time, researchers at the George Washington University have successfully used the gene-editing tool CRISPR/Cas9 to limit the impact of parasitic worms responsible for schistosomiasis and for liver fluke infection, which can cause a diverse spectrum of human disease including bile duct cancer.   (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - January 15, 2019 Category: Cancer & Oncology Source Type: news

States with fewer melanoma diagnoses have higher death rates
(University of Utah Health) Researchers at University of Utah Health conducted a state-by-state analysis to understand the geographic disparities for patients diagnosed with melanoma. The results of their study suggest that lower survival is associated with more practicing physicians in a region and higher population of Caucasians. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - January 15, 2019 Category: Cancer & Oncology Source Type: news

Personalized treatment benefits kidney cancer patients
(Radiological Society of North America) Personalized treatment plans may extend life expectancy for early-stage kidney cancer patients who have risk factors for worsening kidney disease, according to a new study. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - January 15, 2019 Category: Cancer & Oncology Source Type: news

Hope for New Apoptotic Regulatory Pathway in Treating Non-Melanoma Skin Cancers
Researchers studied whether the mechanistic target of mTORC2 directs UVB –induced apoptosis by regulating the expression of NOXA downstream of FOXO3a. (Source: CancerNetwork)
Source: CancerNetwork - January 15, 2019 Category: Cancer & Oncology Authors: Naveed Saleh, MD, MS Source Type: news

Newly Discovered Mechanism Helps Our Own Immune Systems Fight Cancer
“When the mechanism is deactivated, the immune system becomes much more aggressive against the tumor cells, " scientist says. (Source: Forbes.com Healthcare News)
Source: Forbes.com Healthcare News - January 15, 2019 Category: Pharmaceuticals Authors: Robin Seaton Jefferson, Contributor Source Type: news

Why do doctors miss the menace that kills more women than breast cancer?
While cardiovascular disease is perceived by many as a man ’s disease, half of the seven million people in the UK living with it are women. (Source: the Mail online | Health)
Source: the Mail online | Health - January 15, 2019 Category: Consumer Health News Source Type: news

Lilly Eyes More Cancer Deals, but Wary of CAR-T, Gene Therapy Lilly Eyes More Cancer Deals, but Wary of CAR-T, Gene Therapy
Eli Lilly and Co remains in the hunt for cancer drugs even after announcing an $8 billion purchase of Loxo Oncology this week, but it plans to remain on the sidelines when it comes to two of the hottest areas of drug development.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - January 15, 2019 Category: Consumer Health News Tags: Medscape Today News Source Type: news

Breast Cancer Incidence Up With Persistent Vasomotor Symptoms
But persistent vasomotor symptoms not associated with decreased breast cancer survival (Source: The Doctors Lounge - Oncology)
Source: The Doctors Lounge - Oncology - January 15, 2019 Category: Cancer & Oncology Tags: Family Medicine, Gynecology, Internal Medicine, Nursing, Oncology, Journal, Source Type: news

Better Palliative Care in Cancer: HealthLeaders Media
(MedPage Today) -- Also, upcoming trends in virtual care (Source: MedPage Today Public Health)
Source: MedPage Today Public Health - January 15, 2019 Category: American Health Source Type: news