Single surface protein boosts multiple oncogenic pathways in acute myeloid leukemia
(Rockefeller University Press) Researchers from the Albert Einstein College of Medicine in New York have discovered that a signaling protein elevated in patients with acute myeloid leukemia (AML) plays a much wider role in the disease than previously thought. The study, which will be published May 17 in the Journal of Experimental Medicine, raises hopes that current efforts to target this signaling protein could be a successful strategy to treat AML and other blood cancers. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - May 17, 2018 Category: Biology Source Type: news

Improving survival in pancreatic cancer with platinum-based chemotherapy
(Johns Hopkins Medicine) A small study of adults with the most common form of pancreatic cancer adds to evidence that patients with BRCA1 or BRCA2 gene mutations long linked to a high risk of breast cancer have poorer overall survival rates than those without the mutations. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - May 17, 2018 Category: International Medicine & Public Health Source Type: news

Sex, viruses and cancer
(The Ottawa Hospital) A new study suggests that a common treatment for erectile dysfunction combined with the flu vaccine may be able to help the immune system mop up cancer cells left behind after surgery. The study, published in OncoImmunology, shows that this unconventional strategy can reduce the spread of cancer by more than 90 percent in a mouse model. It is now being evaluated in a world-first clinical trial. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - May 17, 2018 Category: International Medicine & Public Health Source Type: news

Hookah responsible for over half of tobacco smoke inhaled by young smokers
(University of Pittsburgh Schools of the Health Sciences) Smoking tobacco from a waterpipe, also known as a hookah, accounted for over half of the tobacco smoke volume consumed by young adult hookah and cigarette smokers in the US, a new University of Pittsburgh School of Medicine analysis discovered. In the US, hookah smoking rates are increasing and cigarette smoking rates are decreasing, especially among young adults. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - May 17, 2018 Category: Cancer & Oncology Source Type: news

SLAM-seq defines direct gene-regulatory functions of the BRD4-MYC axis
Defining direct targets of transcription factors and regulatory pathways is key to understanding their roles in physiology and disease. We combined SLAM-seq [thiol(SH)–linked alkylation for the metabolic sequencing of RNA], a method for direct quantification of newly synthesized messenger RNAs (mRNAs), with pharmacological and chemical-genetic perturbation in order to define regulatory functions of two transcriptional hubs in cancer, BRD4 and MYC, and to interrogate direct responses to BET bromodomain inhibitors (BETis). We found that BRD4 acts as general coactivator of RNA polymerase II–dependent transcription...
Source: ScienceNOW - May 17, 2018 Category: Science Authors: Muhar, M., Ebert, A., Neumann, T., Umkehrer, C., Jude, J., Wieshofer, C., Rescheneder, P., Lipp, J. J., Herzog, V. A., Reichholf, B., Cisneros, D. A., Hoffmann, T., Schlapansky, M. F., Bhat, P., von Haeseler, A., Köcher, T., Obenauf, A. C., Popow, Tags: Medicine, Diseases, Molecular Biology reports Source Type: news

Men May Gain More From Cancer Immunotherapy
(Source: Cancercompass News: Other Cancer)
Source: Cancercompass News: Other Cancer - May 17, 2018 Category: Cancer & Oncology Source Type: news

CDC comes close to an all-clear on romaine lettuce as E. coli outbreak nears historic level
It's unlikely that anyone currently has edible romaine lettuce that's contaminated with the toxic strain of E. coli bacteria sickening people nationwide since March. That was the message Wednesday from the Centers for Disease Control and Prevention, and if not exactly a thundering signal of “all clear,” it's pretty close. Romaine lettuce has a shelf life of […]Related:Surrogate mothers ask Supreme Court to stop ‘exploitation’ of women and babiesMore men with low-risk prostate cancer are forgoing aggressive treatmentEbola has infected dozens so far in Congo, killing 19, WHO says (Sou...
Source: Washington Post: To Your Health - May 16, 2018 Category: Consumer Health News Source Type: news

Academics and nutritionists confirm olive oil is essential for good health
(Natural News) The jury’s out: Experts have confirmed that olive oil is essential for good health, thanks to its many medicinal properties. In particular, multiple studies have shown that it possesses anti-cancer, anti-inflammatory, antioxidant, immunity-boosting, and overall nutrition-enhancing properties. Olive oil is also beneficial for the heart, and it protects against diabetes and blood pressure, as... (Source: NaturalNews.com)
Source: NaturalNews.com - May 16, 2018 Category: Consumer Health News Source Type: news

Better Responses to Immunotherapy in Men Better Responses to Immunotherapy in Men
When patients with advanced solid tumors are treated with immune checkpoint inhibitors, only men get double the survival benefits seen with standard cancer therapies.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - May 16, 2018 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

Obese people are more likely to smoke due to 'addictive' genes drawing them to nicotine
Researchers from the International Agency for Research on Cancer, Lyon, found that for every 4.6kg/m2 increase in BMI, the risk of being a smoker rises by up to 19 per cent, which may be due to DNA. (Source: the Mail online | Health)
Source: the Mail online | Health - May 16, 2018 Category: Consumer Health News Source Type: news

Men Do Better than Women on Cancer Immunotherapies
(MedPage Today) -- Overall survival improvement twice as great, meta-analysis finds (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - May 16, 2018 Category: Primary Care Source Type: news

Roche immunotherapy combination increases lung cancer survival - study
(Reuters) - Roche's immunotherapy Tecentriq, given with its older drug Avastin and chemotherapy, improved survival of advanced lung cancer patients by about 30 percent over the combination without Tecentriq, according to interim results of a late stage trial released on Wednesday. (Source: Reuters: Health)
Source: Reuters: Health - May 16, 2018 Category: Consumer Health News Tags: healthNews Source Type: news

Too Few Smokers Get Lifesaving Lung Cancer Tests
Still, guidelines issued by the U.S. Preventive Services Task Force in 2013 say smokers between the ages of 55 and 80 -- whose habit amounts to a pack-a-day for 30 years and otherwise show no symptoms of disease -- should get new low-dose computed tomography (LDCT) screening. (Source: WebMD Health)
Source: WebMD Health - May 16, 2018 Category: Consumer Health News Source Type: news

Good News on Early Breast Cancer: Herceptin Treatment Can Be Shortened
A large, new study shows that the treatment regimen, typically recommended for a year, can be just as effective at 6 months, reducing serious side effects and costs. (Source: NYT Health)
Source: NYT Health - May 16, 2018 Category: Consumer Health News Authors: DENISE GRADY Tags: Breast Cancer Herceptin (Drug) Genentech Inc Earl, Helena M side effects Source Type: news

Too Few Smokers Get Lifesaving Lung Cancer Tests
(Source: The Doctors Lounge - Oncology)
Source: The Doctors Lounge - Oncology - May 16, 2018 Category: Cancer & Oncology Tags: Oncology, Preventive Medicine, News, Source Type: news

Breast Cancer Patients May Shorten Herceptin Regimen: Study
(Source: The Doctors Lounge - Oncology)
Source: The Doctors Lounge - Oncology - May 16, 2018 Category: Cancer & Oncology Tags: Gynecology, Oncology, News, Source Type: news

Merck's Keytruda boosts response in hard-to-treat lung cancer
(Reuters) - The combination of Merck& Co's immunotherapy Keytruda and chemotherapy boosted response rates in patients with advanced hard-to-treat squamous cell lung cancer, the company said on Wednesday. (Source: Reuters: Health)
Source: Reuters: Health - May 16, 2018 Category: Consumer Health News Tags: healthNews Source Type: news

Loxo Oncology's targeted RET drug shows promise in early trial
CHICAGO (Reuters) - An experimental Loxo Oncology Inc drug that targets cancers with mistakes in the RET gene led to tumor shrinkage in nearly 70 percent of patients regardless of where their cancer originated, according to preliminary data from a small study released on Wednesday. (Source: Reuters: Health)
Source: Reuters: Health - May 16, 2018 Category: Consumer Health News Tags: healthNews Source Type: news

Testing for all lung cancer mutations at once found cost effective - study
CHICAGO (Reuters) - Testing advanced lung cancer patients for all of the possible genetic mutations that could be driving their cancer at once is more cost effective than testing for one or a limited number of genes at a time, U.S. researchers reported on Wednesday. (Source: Reuters: Health)
Source: Reuters: Health - May 16, 2018 Category: Consumer Health News Tags: healthNews Source Type: news

Merck KGaA's lung cancer drugs show promise in early-stage trials
FRANKFURT (Reuters) - Germany's Merck KGaA said two of its experimental oncology drugs showed early signs of promise in certain lung cancer patients, potentially helping the company's efforts to find drug-industry partners to share further development costs. (Source: Reuters: Health)
Source: Reuters: Health - May 16, 2018 Category: Consumer Health News Tags: healthNews Source Type: news

A cancer screening flop: Few smokers seek free lung scans
Less than 2 percent of those eligible for lung cancer screening have sought it (Source: ABC News: Health)
Source: ABC News: Health - May 16, 2018 Category: Consumer Health News Tags: Health Source Type: news

Roche breast cancer drug treatment time can be halved - study
(Reuters) - Treating early stage breast cancer patients for just six months with Roche's Herceptin works as well as the current 12-month regimen, researchers who conducted a large clinical trial said on Wednesday. (Source: Reuters: Health)
Source: Reuters: Health - May 16, 2018 Category: Consumer Health News Tags: healthNews Source Type: news

Shorter drug treatment OK for many breast cancer patients
New research suggests that many women with a common and aggressive form of breast cancer that is treated with Herceptin can get by with six months of the drug instead of the usual 12 (Source: ABC News: Health)
Source: ABC News: Health - May 16, 2018 Category: Consumer Health News Tags: Health Source Type: news

For Women With Early Breast Cancer, Herceptin Treatment Can Be Much Shorter
A large, new study shows that the treatment regimen, typically recommended for a year, can be just as effective at 6 months, reducing serious side effects and costs. (Source: NYT Health)
Source: NYT Health - May 16, 2018 Category: Consumer Health News Authors: DENISE GRADY Tags: Breast Cancer Herceptin (Drug) American Society of Clinical Oncology Cambridge University side effects Genentech Inc Source Type: news

Radiomics helps distinguish lung cancer nodules on CT
Examining several radiologic features of lung nodules on CT scans enabled radiologists...Read more on AuntMinnie.comRelated Reading: New service tracks incidental lung nodules on CT scans AI can help distinguish lung nodules on CT scans AI, radiomics help distinguish lung nodules on CT scans Deep-learning algorithm can stratify lung nodule risk Nodule count on CT not linked to lung cancer risk (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - May 16, 2018 Category: Radiology Source Type: news

Cancer patient had a tumour on his oesphagus removed by robots
Neil Jones, 56, from Preston, who suffered from aggressive cancer of the foodpipe, was told the muscle between his throat and stomach had to be removed to help cure his condition. (Source: the Mail online | Health)
Source: the Mail online | Health - May 16, 2018 Category: Consumer Health News Source Type: news

Mathematical Modeling May Guide Cancer Treatment & #039;Holidays & #039;
A Moffitt team suggests mathematical modeling may guide the optimal cancer treatment dosing approach better than MTD. (Source: CancerNetwork)
Source: CancerNetwork - May 16, 2018 Category: Cancer & Oncology Authors: John Schieszer Tags: Breast Cancer Melanoma News Source Type: news

Emissions of a Banned Ozone-Eating Chemical Are Rising Again and Scientists Don ’t Know Why
(WASHINGTON) — Something strange is happening with a now-banned chemical that eats away at Earth’s protective ozone layer: Scientists say there’s more of it — not less — going into the atmosphere and they don’t know where it is coming from. When a hole in the ozone formed over Antarctica, countries around the world in 1987 agreed to phase out several types of ozone-depleting chemicals called chlorofluorocarbons (CFCs). Production was banned, emissions fell and the hole slowly shrank. But starting in 2013, emissions of the second most common kind started rising, according to a study in We...
Source: TIME: Science - May 16, 2018 Category: Science Authors: Seth Borenstein / AP Tags: Uncategorized Environment onetime Source Type: news

Multi-epitope T-cell Vaccine Shows Promise in Ovarian, Breast Cancer
TPIV200 stimulates T cells to attack ovarian and triple negative breast tumor cells that over-express the folate receptor alpha protein. (Source: CancerNetwork)
Source: CancerNetwork - May 16, 2018 Category: Cancer & Oncology Authors: By John Schieszer Tags: Breast Cancer Immuno Oncology News Ovarian Cancer Source Type: news

Sarcopenia Predicts Tumor Recurrence Post Liver Transplantation?
Recurrence risk was greater in sarcopenic patients, and greater alpha-fetoprotein and microvascular invasion were independent risk factors. (Source: CancerNetwork)
Source: CancerNetwork - May 16, 2018 Category: Cancer & Oncology Authors: John Schieszer Tags: Liver, Gallbladder, and Biliary Tract Cancers News Source Type: news

Breast Cancer Patients May Shorten Herceptin Regimen: Study
WEDNESDAY, May 16, 2018 -- For years, the drug Herceptin has helped women with an aggressive form of breast cancer beat the disease. But there's one downside: In a minority of cases, the drug can trigger heart damage. Now, a new study finds that... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - May 16, 2018 Category: General Medicine Source Type: news

Too Few Smokers Get Lifesaving Lung Cancer Tests
WEDNESDAY, May 16, 2018 -- Less than 2 percent of the 7 million Americans who are or once were heavy smokers get screened for lung cancer, new research shows. " Our analysis reveals a markedly low and inadequate rate of lung cancer screening for... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - May 16, 2018 Category: General Medicine Source Type: news

This Will Change Your Mind About Psychedelic Drugs
For years, the field of mental health has been largely barren of meaningful treatment advances. But now, scientists have new hope in the least likely of places: psychedelic drugs. Recent research suggests that certain psychedelic substances can help relieve anxiety, depression, PTSD, addiction and the fear surrounding a terminal diagnosis. “The biggest misconception people have about psychedelics is that these are drugs that make you crazy,” says Michael Pollan, author of the new book How to Change Your Mind: What the New Science of Psychedelics Teaches Us About Consciousness, Dying, Addiction, Depression, and ...
Source: TIME: Health - May 16, 2018 Category: Consumer Health News Authors: Mandy Oaklander Tags: Uncategorized healthytime Mental Health/Psychology Source Type: news

NIH, Northwestern scientists develop potential new approach to stop cancer metastasis
Identified compound blocks the spread of pancreatic and other cancers in various animal models. (Source: National Institutes of Health (NIH) News Releases)
Source: National Institutes of Health (NIH) News Releases - May 16, 2018 Category: American Health Source Type: news

Doctors: My Patient ’ s Smile
I ’ m drawn to the human brain, its unforgiving and protean nature. (Source: NYT Health)
Source: NYT Health - May 16, 2018 Category: Consumer Health News Authors: ABDUL-KAREEM AHMED Tags: Brain Cancer Tumors Hospitals Depression (Mental) Doctors Source Type: news

Photocure Announces Blue Light Cystoscopy with Cysview(R) Now Available for Surveillance of Bladder Cancer
OSLO, Norway, May 16, 2018 -- (Healthcare Sales & Marketing Network) -- Photocure ASA (OSE: PHO), May 16, 2018, announced today the launch of Blue Light Cystoscopy (BLC™) with Cysview for a new indication of surveillance cystoscopy of bladder cancer. ... Devices, Diagnostics, Oncology, Product Launch Photocure, Karl Storz, Blue Light Cystoscopy, Cysview, bladder cancer (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - May 16, 2018 Category: Pharmaceuticals Source Type: news

Cancer patient, 56, had an aggressive 7cm tumour on his oesphagus removed by ROBOTS
Neil Jones, 56, from Preston, who suffered from aggressive cancer of the foodpipe, was told the muscle between his throat and stomach had to be removed to help cure his condition. (Source: the Mail online | Health)
Source: the Mail online | Health - May 16, 2018 Category: Consumer Health News Source Type: news

Yes or No to Chemo-IO Combo in High PD-L1 NSCLC Patients? Yes or No to Chemo-IO Combo in High PD-L1 NSCLC Patients?
Thoracic oncologists Drs Jack West and Hossein Borghaei talk about when to add chemotherapy to immunotherapy in high PD-L1-expressing non-small cell lung cancer patients.Medscape Oncology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - May 16, 2018 Category: Consumer Health News Tags: Hematology-Oncology Commentary Source Type: news

Auris Health, Ethicon ’ s NeuWave ink robot-assisted bronchoscope ablation dev deal
Auris Health, previously known as Auris Surgical Robotics, said today it inked a cooperative development and commercialization deal with Johnson & Johnson (NYSE:JNJ) division Ethicon’s NeuWave Medical subsidiary looking to develop systems for the robotically-assisted bronchoscopic ablation of lung lesions. Through the agreement, both companies will help develop an integrated system for robotic control, navigation and application of bronchoscope-delivered microwave ablation. The bronchoscope in development will be equipped with a small camera and accessory channel to allow tools to enter the lungs through the...
Source: Mass Device - May 16, 2018 Category: Medical Devices Authors: Fink Densford Tags: Business/Financial News Endoscopic / Arthroscopic Respiratory Robotics aurishealth Ethicon johnsonandjohnson NeuWave Medical Inc. Source Type: news

Surrogate mothers ask Supreme Court to stop ‘exploitation’ of women and babies
Melissa Cook's story became headline news in 2015 when she was carrying triplets as a surrogate. The intended dad asked her to abort at least one of them, she says, because he couldn't afford to raise them all. She refused and has been fighting for custody of the children in court ever since. Cook and two other surrogate mothers — Gail […]Related:More men with low-risk prostate cancer are forgoing aggressive treatmentEbola has infected dozens so far in Congo, killing 19, WHO saysTroubling link found between pollution exposure in pregnancy, high blood pressure in children (Source: ...
Source: Washington Post: To Your Health - May 16, 2018 Category: Consumer Health News Source Type: news

Medical News Today: Could gut bacteria drive colon cancer?
Could gut bacteria impact the development of colon cancer by interacting with molecules that help to regulate gene expression? A recent study investigates. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - May 16, 2018 Category: Consumer Health News Tags: Colorectal Cancer Source Type: news

Managing the cost of cancer treatments
(Source: Karmanos Cancer Institute)
Source: Karmanos Cancer Institute - May 16, 2018 Category: Cancer & Oncology Source Type: news

Colon Polyp Type May Be Key to Cancer Risk
Their study of almost 16,000 patients who underwent colonoscopy found that the long-term risk for colon cancer was 2.5 times greater for those with advanced polyps, compared to people without such growths. (Source: WebMD Health)
Source: WebMD Health - May 16, 2018 Category: Consumer Health News Source Type: news

Prescribe Exercise to All Cancer Patients, Says New Guideline Prescribe Exercise to All Cancer Patients, Says New Guideline
Oncologists should discuss exercise as an adjunct treatment with patients and then prescribe it to everyone, says the Clinical Oncology Society of Australia in a groundbreaking statementMedscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - May 16, 2018 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

Prescribe Exercise to All Patients With Cancer, Says New Guideline Prescribe Exercise to All Patients With Cancer, Says New Guideline
Oncologists should discuss exercise as an adjunct treatment with patients and then prescribe it to everyone, says the Clinical Oncology Society of Australia in a groundbreaking statementMedscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - May 16, 2018 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

PPD Skin Test Enhances Bacillus Calmette-Gu & eacute;rin Tx in Bladder CA
WEDNESDAY, May 16, 2018 -- For patients with non-muscle invasive bladder cancer, undergoing the purified protein derivative skin test prior to bacillus Calmette-Gu érin therapy may have therapeutic impact, according to a study published in the June... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - May 16, 2018 Category: Pharmaceuticals Source Type: news

Higher CRC Risk With Advanced Adenoma Found on Colonoscopy
WEDNESDAY, May 16, 2018 -- Participants with an advanced adenoma at diagnostic colonoscopy have increased risk of developing colorectal cancer (CRC) relative to those with no adenoma, according to a study published in the May 15 issue of the Journal... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - May 16, 2018 Category: Pharmaceuticals Source Type: news

Like Tessa Jowell, I have a brain tumour. I hope her death inspires new research | Jessica Morris
It ’s hard to attract research funding for this complex disease, with a mountain of patient experience going undocumentedMany people are grieving the untimelydeath of Tessa Jowell. She was an exceptional person. Tony Blair confirmed the impression she gave to those of us who only knew her from afar: “Tessa had passion, determination and simple human decency in greater measure than any person I have ever known.”For me, her death is personal for another reason. We found ourselves in the same elite club.Continue reading... (Source: Guardian Unlimited Science)
Source: Guardian Unlimited Science - May 16, 2018 Category: Science Authors: Jessica Morris Tags: Cancer Medical research Health Society Tessa Jowell Politics Science UK news Source Type: news

YouTube begins banning video channels for talking about CBD oil; claims CBD oil "poses risk of serious physical harm or death"
(Natural News) Jumping in bed with Big Pharma and the corrupt cancer industry, YouTube has begun banning entire video channels that post videos describing the compassionate use of CBD oil in cancer patients. In addition to re-banning the Health Ranger video channel over a video that called for racial unity and peace in our world... (Source: NaturalNews.com)
Source: NaturalNews.com - May 16, 2018 Category: Consumer Health News Source Type: news

Bruises on five year-old girl's legs turn out to be CANCER
The family of five-year-old Kaiya Patel (inset), from London, are appealing for a stem cell donor to save their daughter's life after she developed a rare and aggressive form of leukaemia. (Source: the Mail online | Health)
Source: the Mail online | Health - May 16, 2018 Category: Consumer Health News Source Type: news