Some brain tumors may respond to immunotherapy, new study suggests
(Columbia University Irving Medical Center) A new study suggests that a slow-growing brain tumor arising in patients affected by neurofibromatosis type 1 (NF1) may be vulnerable to immunotherapy, which gives the immune system a boost in fighting cancer. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - December 10, 2018 Category: International Medicine & Public Health Source Type: news

Sprayable gel could help the body fight off cancer after surgery
(University of California - Los Angeles Health Sciences) A UCLA-led research team has developed a spray gel embedded with immune-boosting drugs that could help lower the risk of cancer recurrence after surgery. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - December 10, 2018 Category: International Medicine & Public Health Source Type: news

Researchers image atomic structure of important immune regulator
(Brigham and Women's Hospital) A new study by investigators from Brigham and Women's Hospital provides a biophysical and structural assessment of a critical immune regulating protein called human T-cell immunoglobulin and mucin domain containing protein-3 (hTIM-3). Understanding the atomic structure of hTIM-3 provides new insights for targeting this protein for numerous cancer and autoimmune therapeutics currently under clinical development. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - December 10, 2018 Category: International Medicine & Public Health Source Type: news

MD Anderson study shows key enzyme linked to therapy resistance in deadly lung cancer
(University of Texas M. D. Anderson Cancer Center) Researchers at The University of Texas MD Anderson Cancer Center have identified a link between an enzyme tied to cancer formation and therapy resistance in patients with epidermal growth factor receptor (EGFR)-mutant non-small cell lung cancer (NSCLC). They believe two existing therapies may hold promise for clinical studies for this deadly and common lung cancer for which relapse often occurs within one year following treatment. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - December 10, 2018 Category: Cancer & Oncology Source Type: news

Media Advisory: Young age associated with worse prognosis in specific breast cancer subtype
(Johns Hopkins Medicine) Researchers at Johns Hopkins Kimmel Cancer Center are rapidly advancing the understanding of biological factors, including hormones, as predictors of longer disease-free survival for certain subtypes of breast cancer. The implications for treatment -- especially among younger women -- can be profound, but uncertainties remain and decision-making by patients and their physicians can be complicated. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - December 10, 2018 Category: Cancer & Oncology Source Type: news

How does cancer spread?
(McGill University Health Centre) How does cancer spread? While studying human brain tumour cells, a team of scientists at the Research Institute of the McGill University Health Centre (RI-MUHC) found some answers to this crucial, yet so far unanswered question. They looked at a gene called EGFRvIII, which is present in patients with glioblastoma -- a highly aggressive form of brain cancer that spreads quickly and that is difficult to treat. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - December 10, 2018 Category: Cancer & Oncology Source Type: news

Cancer cells distinguished by artificial intelligence-based system
(Osaka University) A research team at Osaka University created a system that uses a convolutional neural network to learn the features distinguishing different cancer cells, based on images from a phase-contrast microscope. This system accurately differentiated human and mouse cancer cells, as well as their radioresistant clones. This novel approach can improve the speed and accuracy of cancer diagnosis by avoiding the laboriousness and potential errors associated with equivalent analyses by humans. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - December 10, 2018 Category: Cancer & Oncology Source Type: news

New insights into childhood cancer
(Charit é - Universit ä tsmedizin Berlin) Peripheral nervous system tumors, known as neuroblastoma, are one of the most common types of childhood tumors. As part of an international research endeavor, researchers from Charit é - Universit ä tsmedizin Berlin have studied the genetic factors behind different tumor subtypes and their prognoses. Their findings enable clinicians to predict the precise clinical course of the disease, and to adapt their treatment regimens accordingly. The study has been published in the prestigious journal Science*. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - December 10, 2018 Category: Cancer & Oncology Source Type: news

Breast cancer recruits bone marrow cells to increase cancer cell proliferation
(American Friends of Tel Aviv University) Tel Aviv University researchers have discovered that breast cancer tumors boost their growth by recruiting stromal cells that originate in bone marrow. The study suggests that targeting these cells with new therapies could be an effective way of treating the disease. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - December 10, 2018 Category: Cancer & Oncology Source Type: news

Interplay between MicroRNAs and targeted genes in cellular homeostasis of adult zebrafish
The objective of study was to understand the damages induced by toxins in the liver and the intestine as well as the interplay between the miRNome and transcriptome baseline characterization in these tissues in healthy animals under cellular homeostasis. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - December 10, 2018 Category: Cancer & Oncology Source Type: news

Researchers develop personalized medicine tool for inherited colorectal cancer syndrome
(Huntsman Cancer Institute) An international team of researchers led by Huntsman Cancer Institute (HCI) at the University of Utah (U of U) has developed, calibrated, and validated a novel tool for identifying the genetic changes in Lynch syndrome genes that are likely to be responsible for causing symptoms of the disease. The results were published this week in the journal Genetics in Medicine. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - December 10, 2018 Category: Cancer & Oncology Source Type: news

Increased cervical cancer risk in women with positive HPV, but no cellular abnormalities
(Wiley) Researchers have uncovered an increased risk of cervical cancer in women whose cervical cells test positive for certain high-risk human papillomavirus (HPV) types but do not show any signs of cellular abnormalities. Published early online in CANCER, a peer-reviewed journal of the American Cancer Society, the findings may help refine guidelines for cervical cancer screening. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - December 10, 2018 Category: Cancer & Oncology Source Type: news

Breast cancer screening: New emphasis on shared decision-making between women and their doctors
(Canadian Medical Association Journal) An updated guideline on screening for breast cancer emphasizes shared decision-making between women and their doctors, supporting women to make an informed decision based on personal preferences when the balance between benefits and harms is uncertain. The guideline, released by the Canadian Task Force on Preventive Health Care, is published in CMAJ (Canadian Medical Association Journal). (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - December 10, 2018 Category: Cancer & Oncology Source Type: news

#MayoClinicRadio podcast: 12/8/18
Listen: Mayo Clinic Radio 12/8/18 On the Mayo Clinic Radio podcast, Dr. John Kisiel, a gastroenterologist at Mayo Clinic, discusses screening, treatment and prevention of colorectal cancer.?Also on the podcast, Dr. Matthew Ferber, a medical geneticist at Mayo Clinic, explains?Mayo Clinic GeneGuide. GeneGuide is the new personal DNA product backed by Mayo medical science and [...] (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - December 10, 2018 Category: Databases & Libraries Source Type: news

Why Cancer Treatment Can Differ For Those Who Aren't Married
New research shows that cancer patients who are single receive less aggressive treatment than those who are married. NPR's Michel Martin talks with researcher Joan DelFattore about her findings. (Source: NPR Health and Science)
Source: NPR Health and Science - December 9, 2018 Category: Consumer Health News Source Type: news

The 5 things you need to do to prevent liver cancer
(Natural News) Are you overweight? Do you drink or smoke a lot? If you answered “yes” to some or all of these questions, you may be at risk of developing liver cancer. The best way to lower your risk of developing this type of cancer is by making some lifestyle changes. Here are five things... (Source: NaturalNews.com)
Source: NaturalNews.com - December 9, 2018 Category: Consumer Health News Source Type: news

Prophylaxis May Cut Cardiotoxicity Risk in HER+ Breast Cancer
(MedPage Today) -- Clear benefit for anthracycline treatment, not trastuzumab (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - December 9, 2018 Category: Cardiology Source Type: news

Could inflammation be the core cause of all chronic disease?
(Natural News) A lot of blame is passed around when talking about illness. You’ve probably heard a lot of common beliefs about what causes disease – some true and some a bit misinformed. For example, it’s often said that eating too much sugar causes diabetes, spending too much time in the sun causes skin cancer,... (Source: NaturalNews.com)
Source: NaturalNews.com - December 8, 2018 Category: Consumer Health News Source Type: news

Cancer warning - five cold and flu signs that may be something more serious
CANCER symptoms vary depending on which part of the body is affected by a tumour. This winter, you could be developing more signs of a cold or the flu. These are the cancer symptoms that you may be overlooking. (Source: Daily Express - Health)
Source: Daily Express - Health - December 8, 2018 Category: Consumer Health News Source Type: news

Medical News Today: Is it possible to reverse 'chemo brain?'
'Chemo brain' affects many people who have undergone cancer treatment. What happens in the brain, and how can we reverse this effect? (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - December 8, 2018 Category: Consumer Health News Tags: Cancer / Oncology Source Type: news

Trilobites: Seeking Clues to Longevity in Lonesome George ’ s Genes
The giant tortoise lived for more than a century, carrying genes linked to a robust immune system, efficient DNA repair and resistance to cancer. (Source: NYT Health)
Source: NYT Health - December 8, 2018 Category: Consumer Health News Authors: STEPH YIN Tags: Turtles and Tortoises Genetics and Heredity Longevity Evolution (Biology) Galapagos Islands Nature Ecology & Evolution (Journal) Caccone, Adalgisa Lopez-Otin, Carlos Source Type: news

Vicky Phelan: The woman who exposed an Irish health scandal
Vicky Phelan exposed a health scandal in Ireland after discovering her smear test for cervical cancer had been misread. (Source: BBC News | Health | UK Edition)
Source: BBC News | Health | UK Edition - December 8, 2018 Category: Consumer Health News Source Type: news

Science Saturday: Finding the right drug, dose for cancer therapy through pharmacogenomics
Each year, nearly 300,000 patients receive the lifesaving chemotherapy 5-fluorouracil (5-FU) to treat many types of cancer, including colorectal, breast, bowel, skin, pancreatic, and esophageal cancer. While it can be an effective treatment, it doesn?t work for everyone. In fact, up to 30 percent of those who receive the standard dose can have serious, life-threatening [...] (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - December 8, 2018 Category: Databases & Libraries Source Type: news

Can Radiotherapy Reduce the Need for Axillary Surgery?
The AMAROS trial tested RT to the axillary lymph node against ALND to see if some of the morbidity associated with surgery for breast cancer could be avoided. (Source: CancerNetwork)
Source: CancerNetwork - December 7, 2018 Category: Cancer & Oncology Authors: Dave Levitan Source Type: news

What Effect Do Surgical Choices Have on Quality of Life in Young Breast Cancer Survivors?
Unilateral or bilateral mastectomy can have a significant effect on quality of life when compared with breast-conserving surgery in young breast cancer survivors. (Source: CancerNetwork)
Source: CancerNetwork - December 7, 2018 Category: Cancer & Oncology Authors: Dave Levitan Source Type: news

Cancer Network Conferences
(Source: CancerNetwork)
Source: CancerNetwork - December 7, 2018 Category: Cancer & Oncology Source Type: news

Is Cardiac Prophylaxis Effective in Early HER2+ Breast Cancer Patients?
In patients with HER2-positive breast cancer treated with anthracyclines plus trastuzumab, can adding lisinopril or carvedilol reduce the risk of cardiotoxicity? (Source: CancerNetwork)
Source: CancerNetwork - December 7, 2018 Category: Cancer & Oncology Authors: Dave Levitan Source Type: news

Testing a Lifestyle Intervention to Improve Outcomes in Early Breast Cancer
A study of a lifestyle intervention looked for improvement in disease-free or overall survival in early breast cancer patients. (Source: CancerNetwork)
Source: CancerNetwork - December 7, 2018 Category: Cancer & Oncology Authors: Dave Levitan Source Type: news

Patients Say Quality of Life Suffered With Mastectomy for Early Breast Cancer
(MedPage Today) -- Breast-conservation options were associated with better sexual, psychosocial outcomes (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - December 7, 2018 Category: Hematology Source Type: news

Regular Exercise Benefits Breast Cancer Survivors Post-Surgery
(MedPage Today) -- Improves cardiac function, helps in weight reduction (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - December 7, 2018 Category: Cardiology Source Type: news

The naked eye is NOT strong enough to diagnose skin cancer
The review was led by the University of Birmingham, with scientists stressing doctors should make greater use of magnifying devices and send images off to a more senior specialist if unsure. (Source: the Mail online | Health)
Source: the Mail online | Health - December 7, 2018 Category: Consumer Health News Source Type: news

PET tracers help guide breast cancer therapies
PET imaging tracers that track breast cancer enzymes could help guide treatment...Read more on AuntMinnie.comRelated Reading: SNMMI: Fluciclovine-PET changes prostate treatment Mammi-PET finds tiny breast lesions -- but could improve Fused MRI and PET improve specificity of breast MRI PEM performs well against breast MRI, whole-body PET NCPIC to provide PET breast scans for uninsured (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - December 7, 2018 Category: Radiology Source Type: news

Visual Guide to AVERT's VTE Prevention in Cancer
(MedPage Today) -- Apixaban effective against important chemotherapy side effect (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - December 7, 2018 Category: Cardiology Source Type: news

Mice experiments could bring doctors closer to accurate liver cancer diagnosis
New research into a hormone common in mice may lead to better liver cancer treatment in humans, a study says. (Source: Health News - UPI.com)
Source: Health News - UPI.com - December 7, 2018 Category: Consumer Health News Source Type: news

In Lupus, Risks for Cancers Rise
(MedPage Today) -- Overall risks increased for both women and men (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - December 7, 2018 Category: Hematology Source Type: news

Valsartan Blood Pressure Drug Recall Widens
The drugs were recalled because of trace amounts of an impurity, N-nitrosodiethylamine, or NDEA, which may cause cancer in humans, according to the International Agency for Research on Cancer. (Source: WebMD Health)
Source: WebMD Health - December 7, 2018 Category: Consumer Health News Source Type: news

Uterine cancer rates rising, particularly among black women
Uterine cancer is on the rise in the U.S. and it's killing black women at a higher rate than any other group, a report says. (Source: Health News - UPI.com)
Source: Health News - UPI.com - December 7, 2018 Category: Consumer Health News Source Type: news

Free Beer, Wine After Alcohol Warning at Cancer Meeting Free Beer, Wine After Alcohol Warning at Cancer Meeting
On opening night, an epidemiologist told meeting attendees that any alcohol intake was associated with an increased breast cancer risk. The next night, the organizers provided free beer and wine to attendees.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - December 7, 2018 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

Breast cancer survivors may have lingering mental health effects
(Reuters Health) - - Breast cancer survivors may be more likely to experience anxiety, depression, sleep troubles and other mental health issues than women who have not been diagnosed with the disease, a research review suggests. (Source: Reuters: Health)
Source: Reuters: Health - December 7, 2018 Category: Consumer Health News Tags: healthNews Source Type: news

Drug May Cut Hot Flashes After Breast Cancer
A familiar drug for urinary incontinence has been found to reduce hot flashes in women after breast cancer. (Source: WebMD Health)
Source: WebMD Health - December 7, 2018 Category: Consumer Health News Source Type: news

Liver cancer symptoms: Eight signs you may not associate with the disease
LIVER cancer symptoms tend not to be noticeable until the disease has advanced. They can also be mistaken for less serious health conditions - there are eight symptoms you may not usually associate with the killer disease. (Source: Daily Express - Health)
Source: Daily Express - Health - December 7, 2018 Category: Consumer Health News Source Type: news

Major Trial: Partial Breast Radiation Good for Early Breast Cancer Major Trial: Partial Breast Radiation Good for Early Breast Cancer
Partial breast irradiation was almost equivalant to whole-breast irradiation for disease control and can be considered a valid treatment option for women with early-stage breast cancer.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - December 7, 2018 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

With Same Breast Cancer Care, Black Women Do Worse
In a recent study, leveling the playing field by bringing women to the same doctors and getting the same treatment" didn't equalize breast cancer outcomes between black and white women. (Source: WebMD Health)
Source: WebMD Health - December 7, 2018 Category: Consumer Health News Source Type: news

Uterine Cancer Incidence and Deaths on the Rise in US Uterine Cancer Incidence and Deaths on the Rise in US
Black women in particular need to be more aware of the symptoms of uterine cancer to stem the rise in the incidence and mortality rates of uterine cancer in the US, warn CDC experts.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - December 7, 2018 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

Older adults may be unwilling to give up colorectal screening
(Reuters Health) - At age 76 the risks of a repeat colonoscopy may exceed the benefits for seniors whose previous screenings have found no signs of cancer, but many older adults don't like the logic behind this guideline based on life expectancy. (Source: Reuters: Health)
Source: Reuters: Health - December 7, 2018 Category: Consumer Health News Tags: healthNews Source Type: news

Roche wins key lung cancer combo approval
Roche Holding ’s Tecentriq immunotherapy, in combination with Avastin and chemotherapy, won U.S. FDA approval as a first-line treatment for a type of lung cancer. (Source: PharmaManufacturing.com)
Source: PharmaManufacturing.com - December 7, 2018 Category: Pharmaceuticals Source Type: news

SABCS: Axillary RT as Good as Surgery in Breast Cancer
(MedPage Today) -- Radiation non-inferior to surgery after positive sentinel node (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - December 7, 2018 Category: Hematology Source Type: news

Surgery or Endocrine Therapy for Breast CA in Older Women? Surgery or Endocrine Therapy for Breast CA in Older Women?
Dr Lowenfels challenges the findings of a recent study that suggests surgery as the better option in treating older women with early-stage breast cancer.Medscape General Surgery (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - December 7, 2018 Category: Consumer Health News Tags: General Surgery Viewpoint Source Type: news

Incontinence Drug May Cut Hot Flashes in Breast Cancer Survivors
(Source: The Doctors Lounge - Oncology)
Source: The Doctors Lounge - Oncology - December 7, 2018 Category: Cancer & Oncology Tags: Gynecology, Oncology, Pharmacy, News, Source Type: news

Healthy Lifestyle Lowers Odds of Breast Cancer ’ s Return
(Source: The Doctors Lounge - Oncology)
Source: The Doctors Lounge - Oncology - December 7, 2018 Category: Cancer & Oncology Tags: Family Medicine, Gynecology, Oncology, Sports Medicine, Nutrition, News, Source Type: news