Noninvasive Diagnostic Imaging Accurately IDs Bladder Cancer
TUESDAY, Dec. 4, 2018 -- Noninvasive diagnostic imaging using machine-learning analysis of nanoresolution images of cell surfaces can detect bladder cancer with high diagnostic accuracy, according to research published online Dec. 3 in the... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - December 4, 2018 Category: Pharmaceuticals Source Type: news

Prostate cancer - does your wee look like this? Warning signs when you use the toilet
PROSTATE cancer symptoms are difficult to spot in its early stages, but can affect the way you use the toilet. You could be at risk of the condition ’s signs if your urine looks like this. (Source: Daily Express - Health)
Source: Daily Express - Health - December 4, 2018 Category: Consumer Health News Source Type: news

Red tape preventing cancer patients from accessing new drugs
Some cancers have had no new drugs licensed since 2000, according to Institute of Cancer Research reportCancer patients are missing out on innovative new drugs, with red tape covering clinical trials and licensing among the factors to blame, according to a report by theUK ’s Institute of Cancer Research.Children ’s cancers have received little in the way of new treatments, a finding the authors put down to drug companies failing to invest in these rare conditions and using regulatory loopholes to avoid conducting the necessary clinical trials.Continue reading... (Source: Guardian Unlimited Science)
Source: Guardian Unlimited Science - December 4, 2018 Category: Science Authors: Nicola Davis Tags: Cancer research Medical research Science Health Drugs Society NHS Health policy UK news Source Type: news

Amgen antibody shows promise in myeloma trial, gets FDA fast track
Amgen Inc, updating the first trial of its bispecific antibody for multiple myeloma, said on Monday seven out of 10 patients given the second-highest dose of AMG420 responded to the drug, including four with no detectable cancer. (Source: Reuters: Health)
Source: Reuters: Health - December 4, 2018 Category: Consumer Health News Tags: healthNews Source Type: news

Money ills add to cancer struggle
(University of Technology Sydney) One in five cancer patients could be experiencing financial difficulties because of their care needs, according to new research published in the Journal of Cancer Survivorship. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - December 4, 2018 Category: Cancer & Oncology Source Type: news

Can rice and flushing the toilet be slowly poisoning you?
(Society for Risk Analysis) Rice, barbecued meat and drinking water all pose threats to human health as hosts to potent toxins, carcinogens and opportunistic pathogens. In many cases, the rise in concentrations of these harmful substances is a direct result of human activity, such as the use of harmful pesticides in crops and even advances in green technology. Risk assessment can be a useful tool for determining the actual threat to human health with numerous variables between population groups and degrees of uncertainty. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - December 4, 2018 Category: Cancer & Oncology Source Type: news

Expanded cord blood shows potential for use in adult bone marrow transplants
(Duke University Medical Center) Umbilical cord blood stem cells that are cultured and expanded outside the body before being used for bone marrow transplant in adult blood cancer patients appear safe and restore blood count recovery faster than standard cord blood. The findings advance efforts to improve cord blood use among adults who have been diagnosed with blood cancers. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - December 4, 2018 Category: Cancer & Oncology Source Type: news

Institute of Human Virology researchers discover that a bacterial protein promotes cancer
(University of Maryland School of Medicine) The Institute of Human Virology (IHV) at the University of Maryland School of Medicine (UMSOM) announced today the discovery that DnaK, a protein of the bacterium mycoplasma, interferes with the mycoplasma-infected cell's ability to respond to and repair DNA damage, a known origin of cancer. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - December 4, 2018 Category: International Medicine & Public Health Source Type: news

SWOG shares trio of studies at San Antonio breast cancer symposium
(SWOG) SWOG Cancer Research Network members will share the results of three studies at the San Antonio Breast Cancer Symposium, an international gathering of breast cancer physicians and researchers that starts today, with an estimated 7,500 attendees expected from more than 90 countries. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - December 4, 2018 Category: International Medicine & Public Health Source Type: news

New cancer immunotherapy approach turns immune cells into tiny anti-tumor drug factories
(University of California - San Diego) In lab and mouse experiments, UC San Diego School of Medicine researchers developed a method to leverage B cells to manufacture and secrete tumor-suppressing microRNAs. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - December 4, 2018 Category: Biology Source Type: news

Cleveland Clinic-led study: Rivaroxaban reduced blood clots and related death in cancer patients
(Cleveland Clinic) Cleveland Clinic medical oncologist and researcher, Alok Khorana, M.D., is the primary investigator on a study that concluded rivaroxaban for venous thromboembolism (VTE), a blood clot in the venous system, significantly reduced VTE and VTE-related death for outpatient, at-risk cancer patients while they were taking the oral blood thinner. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - December 4, 2018 Category: Cancer & Oncology Source Type: news

A universal DNA nano-signature for cancer
(University of Queensland) Researchers from the University of Queensland's Australian Institute for Bioengineering and Nanotechnology (AIBN) have discovered a unique nano-scaled DNA signature that appears to be common to all cancers. Based on this discovery, the team has developed a novel technology that enables cancer to be quickly and easily detected from any tissue type, e.g. blood or biopsy. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - December 4, 2018 Category: Cancer & Oncology Source Type: news

Drug dramatically reduces risk of dangerous blood clots in cancer patients
(The Ottawa Hospital) A large clinical trial published in the New England Journal of Medicine provides the first approach for safely preventing blood clots (venous thromboembolism) in people with cancer. Venous thromboembolism is the second leading cause of death in cancer patients and it can also affect quality of life. About half of people newly diagnosed with a solid cancer could be candidates for the strategy, which involves a low dose of a direct oral anticoagulant called apixaban. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - December 4, 2018 Category: Cancer & Oncology Source Type: news

New possible target for treating major common diseases
(Karolinska Institutet) There is a large, untapped potential for developing drugs against cancer, fibrosis and cardiovascular diseases by targeting a family of receptors known as Frizzleds, researchers at Karolinska Institutet in Sweden believe. In a new study published in Science Signaling, they identify how these receptors are activated in the cell membrane and the processes that are then triggered within the cell. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - December 4, 2018 Category: Cancer & Oncology Source Type: news

The 'wrong' connective tissue cells signal worse prognosis for breast cancer patients
(Lund University) In certain forms of cancer, connective tissue forms around and within the tumour. One previously unproven theory is that there are several different types of connective tissue cells with different functions, which affect the development of the tumour in different ways. Now, a research team at Lund University in Sweden has identified three different types of connective tissue cells. In studies of breast cancer patients, the team found that two of these are linked to a worse prognosis. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - December 4, 2018 Category: Cancer & Oncology Source Type: news

Realistic exposure study supports the use of zinc oxide nanoparticle sunscreens
(Elsevier) An important new study provides the first direct evidence that intact zinc oxide nanoparticles neither penetrate the human skin barrier nor cause cellular toxicity after repeated application to human volunteers under in-use conditions. This confirms that the known benefits of using ZnO nanoparticles in sunscreens clearly outweigh the perceived risks, reports the Journal of Investigative Dermatology. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - December 4, 2018 Category: Cancer & Oncology Source Type: news

New cancer immunotherapy approach turns human cells into tiny anti-tumor drug factories
(University of California - San Diego) In lab and mouse experiments, UC San Diego School of Medicine researchers developed a method to leverage B cells to manufacture and secrete tumor-suppressing microRNAs. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - December 4, 2018 Category: Cancer & Oncology Source Type: news

Immunotherapy pioneers reveal updated efficacy data of tisagenlecleucel CAR T-cell therapy
(Children's Hospital of Philadelphia) Physician-scientists from Children's Hospital of Philadelphia presented updated efficacy and safety data on Kymriah (tisagenlecleucel, formerly CTL019) -- the first-ever FDA-approved personalized CAR T-cell gene immunotherapy for aggressive blood cancers, at the 60th American Society of Hematology annual meeting, as well as first-of-its-kind research on overcoming CAR T-cell resistance. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - December 4, 2018 Category: Cancer & Oncology Source Type: news

Oral cancer prognostic signature identified
(Funda ç ã o de Amparo à Pesquisa do Estado de S ã o Paulo) Discovery based on analysis of tissue and saliva samples from oral cancer patients shows a correlation between a signature comprising three peptides and the presence of lymph node metastasis. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - December 4, 2018 Category: Cancer & Oncology Source Type: news

Russian scientists developed a new drug for cancer diagnostics and treatment
(Sechenov University) Russian researchers announced the development of a combined action drug based on ionizing radiation and bacterial toxin. Their total effect appeared to be 2,200 times stronger compared to that exerted by the radiation and toxin, separately. The drug affects tumor cells selectively providing better diagnostics and treatment of malignant tumors (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - December 4, 2018 Category: Biology Source Type: news

Flexibility on cancer drugs approval is essential
It now takes more than a year longer than in the 2000s for medicines to reach patients (Source: FT.com - Drugs and Healthcare)
Source: FT.com - Drugs and Healthcare - December 4, 2018 Category: Pharmaceuticals Source Type: news

Amgen's AMG420 shows responses in myeloma trial, gets FDA fast track
Amgen Inc, updating the first trial of its bispecific antibody for multiple myeloma, on Monday said seven out of ten patients given the second-highest dose of AMG420 responded to the drug, including four with no detectable cancer. (Source: Reuters: Health)
Source: Reuters: Health - December 4, 2018 Category: Consumer Health News Tags: healthNews Source Type: news

Rare Variants Associated With Interval Breast Cancers
The presence of these variants is also linked to increased risk for death (Source: The Doctors Lounge - Oncology)
Source: The Doctors Lounge - Oncology - December 4, 2018 Category: Cancer & Oncology Tags: Gynecology, Oncology, Pathology, Journal, Source Type: news

Despite innovation, Europeans wait years for new cancer drugs
Rapid advances in cancer science have increased the number of new oncology drugs being developed, but delays in regulation and approvals mean patients in Europe often wait years to be able to access them, researchers said on Tuesday. (Source: Reuters: Health)
Source: Reuters: Health - December 4, 2018 Category: Consumer Health News Tags: healthNews Source Type: news

Mayo Clinic researchers identify new strategies that may improve CAR-T cell therapy
SAN DIEGO ??Mayo Clinic researchers have developed two new strategies that may improve the performance of chimeric antigen receptor therapy (CAR-T cell therapy) in treating cancer. They are presenting results of their preclinical research at the 2018 annual meeting of the American Society of Hematology in San Diego. Reducing toxicity in CAR-T cell therapy ?While [...] (Source: Mayo Clinic Minnesota News)
Source: Mayo Clinic Minnesota News - December 4, 2018 Category: Hospital Management Source Type: news

BioPlus Specialty Pharmacy Now Dispensing Newly Approved AML Cancer...
BioPlus Specialty Pharmacy, one of the nation’s leading innovative specialty pharmacies, can now dispense the latest FDA-approved limited distribution medication Daurismo (glasdegib) for acute myeloid...(PRWeb December 04, 2018)Read the full story at https://www.prweb.com/releases/bioplus_specialty_pharmacy_now_dispensing_newly_approved_aml_cancer_medication_daurismo/prweb15964353.htm (Source: PRWeb: Medical Pharmaceuticals)
Source: PRWeb: Medical Pharmaceuticals - December 4, 2018 Category: Pharmaceuticals Source Type: news

Most ovarian cysts may not need surveillance
Women with simple ovarian cysts detected by ultrasound didn ’t develop ovarian cancer at elevated rates over the next three years, adding to evidence that these cysts aren’t dangerous. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - December 4, 2018 Category: Consumer Health News Source Type: news

Statins are being overprescribed, study suggests
The risks of statins for primary prevention are greater than the benefits for many patients Related items fromOnMedica Withdrawn valsartan meds not linked to short-term cancer risk Direct oral anticoagulants as safe as warfarin after VTE Too few women take part in many CVD clinical trials Use of DPP-4 inhibitors associated with increased risk of IBD Metformin doesn ’t help HbA1c in teens with type 1 diabetes (Source: OnMedica Latest News)
Source: OnMedica Latest News - December 4, 2018 Category: UK Health Source Type: news

Red tape delaying availability of new cancer drugs
Report also criticises NICE for lack of emphasis on innovation when assessing new drugs Related items fromOnMedica Is crowdfunding for cancer patients paying for ‘quackery’? Cancer patients using complementary meds die sooner New targeted drug could help treat advanced cancers Prediction tool to help develop better cancer drugs Exercise and psychological treatments cut cancer fatigue (Source: OnMedica Latest News)
Source: OnMedica Latest News - December 4, 2018 Category: UK Health Source Type: news

Rogue 'protein factories' point to potential cancer treatments
Cells are packed with proteins, encoded by the recipes in our genes. An EU-funded researcher has discovered key differences in protein production between healthy cells and tumours, revealing exciting potential avenues for the development of future cancer treatments. (Source: EUROPA - Research Information Centre)
Source: EUROPA - Research Information Centre - December 4, 2018 Category: Research Source Type: news

Janssen affiliate and Dutch company ink $1.6B deal to develop cancer drug
Cilag, an affiliate of Janssen, is teaming up with a Netherlands-based biopharmac company called Argenx to develop a treatment for certain cancers. (Source: PharmaManufacturing.com)
Source: PharmaManufacturing.com - December 3, 2018 Category: Pharmaceuticals Source Type: news

The real link between sugar consumption and cancer
(Natural News) There are over 37 trillion cells in the average living person. Each cell is like a living organism. Each cell requires energy and must produce energy to carry out vital functions; that cellular energy is mainly created from the healthy metabolism and electron transfer of macro-nutrients and micro-nutrients from the foods that we... (Source: NaturalNews.com)
Source: NaturalNews.com - December 3, 2018 Category: Consumer Health News Source Type: news

Lung cancer symptoms: Six signs the disease is advanced and has spread outside the lungs
LUNG cancer symptoms don ’t tend to show until the tumour in the lungs has grown. But sometimes, when the disease has advanced and spread outside the lungs, a host of symptoms not related to the chest may be the first to show. Here are six to watch out for. (Source: Daily Express - Health)
Source: Daily Express - Health - December 3, 2018 Category: Consumer Health News Source Type: news

Oral drug for blood clot treatment safe for cancer patients, study says
A popular oral medication used to treat blood clots is safe and effective for patients going through cancer therapy, a study says. (Source: Health News - UPI.com)
Source: Health News - UPI.com - December 3, 2018 Category: Consumer Health News Source Type: news

Lung cancer symptoms: Six signs the disease is advanced and spread outside the lungs
LUNG cancer symptoms don ’t tend to show until the tumour in the lungs has grown. But sometimes, when the disease has advanced and spread outside the lungs, a host of symptoms not related to the chest may be the first to show. Here are six to watch out for. (Source: Daily Express - Health)
Source: Daily Express - Health - December 3, 2018 Category: Consumer Health News Source Type: news

Lung cancer symptoms: Six signs the disease has advanced and spread outside the lungs
LUNG cancer symptoms don ’t tend to show until the tumour in the lungs has grown. But sometimes, when the disease has advanced and spread outside the lungs, a host of symptoms not related to the chest may be the first to show. Here are six to watch out for. (Source: Daily Express - Health)
Source: Daily Express - Health - December 3, 2018 Category: Consumer Health News Source Type: news

Rare Variants Associated With Interval Breast Cancers
MONDAY, Dec. 3, 2018 -- Though common breast cancer variants indicate increased breast cancer risk, certain rare variants are associated with an increased risk for interval breast cancers and death, according to a study published in the Nov. 1 issue... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - December 3, 2018 Category: Pharmaceuticals Source Type: news

NxThera spinout NxPhase lands $10m for vapor ablation tech
NxPhase Medical – spun out of NxThera when Boston Scientific bought it this year– has raised more than $10 million, according to a recent U.S. Securities and Exchange Commission filing. Maple Grove, Minn.–based NxPhase is focused on using convective thermal water vapor to treat prostate, kidney, and bladder cancer, according to its LinkedIn page. Get the full story on our sister site Medical Design & Outsourcing.  The post NxThera spinout NxPhase lands $10m for vapor ablation tech appeared first on MassDevice. (Source: Mass Device)
Source: Mass Device - December 3, 2018 Category: Medical Devices Authors: Chris Newmarker Tags: Business/Financial News News Well Surgical nxphasemedical NxThera Inc. Source Type: news

Women reluctant to take preventive breast cancer drug, study says
Women were reluctant to take a drug that could prevent them from developing breast cancer, a new study says. (Source: Health News - UPI.com)
Source: Health News - UPI.com - December 3, 2018 Category: Consumer Health News Source Type: news

GSK bets big with Tesaro buy
GlaxoSmithKline has agreed to buy cancer biotech, Tesaro, for $5.1B. (Source: PharmaManufacturing.com)
Source: PharmaManufacturing.com - December 3, 2018 Category: Pharmaceuticals Source Type: news

In death, Lonesome George reveals why giant tortoises live so long
Genetic analysis of Galapagos tortoises like Lonesome George has found they possessed gene variants linked to DNA repair, immunity, and cancer suppression. (Source: Yale Science and Health News)
Source: Yale Science and Health News - December 3, 2018 Category: Universities & Medical Training Source Type: news

Why It ’s Time for All Clinical Laboratories and Anatomic Pathology Groups to have a Genetic Testing and Gene Sequencing Strategy
As personalized medicine becomes more popular, clinical laboratories, and anatomic pathologists are uniquely positioned to use next-generation sequencing to advance their scope among regulators, insurers, providers and patients, while adding clinical value and generating a new revenue source By now, most clinical pathologists and medical laboratory scientists recognize that genetics, genetic testing, and gene sequencing […] (Source: Dark Daily)
Source: Dark Daily - December 3, 2018 Category: Laboratory Medicine Authors: Jude Tags: Digital Pathology Instruments & Equipment Laboratory Instruments & Laboratory Equipment Laboratory Management and Operations Laboratory Pathology Laboratory Testing Management & Operations anatomic pathology Brian Keefe Cancer Treatment Source Type: news

GlaxoSmithKline to Acquire Cancer Biotech TESARO for $5.1 Billion
The purchase aims to build GSK's oncology pipeline. (Source: The Scientist)
Source: The Scientist - December 3, 2018 Category: Science Tags: News & Opinion Source Type: news

Norris Cotton Cancer Center Director Steven Leach Named Fellow of the American Association for the Advancement of Science
Steven D. Leach, MD, director of the Dartmouth-Hitchcock Norris Cotton Cancer Center and the Preston T. and Virginia R. Kelsey Distinguished Chair in Cancer at the Geisel School of Medicine at Dartmouth, has been named a Fellow of the American Association for the Advancement of Science. (Source: News at Dartmouth Medical School)
Source: News at Dartmouth Medical School - December 3, 2018 Category: Hospital Management Authors: Geisel Communications Tags: News Press Release Research AAAS cancer faculty achievement Home-feature Norris Cotton Cancer Center Steven Leach Source Type: news

GSK Buys Tesaro For $5 Billion In Dramatic Bet On Cancer Genetics
The deal is a dramatic bet that the London-based drug giant can see opportunities connected to the genetics of cancer drugs better than the stock market. It fits into a framework outlined in July by Hal Barron, the widely respected pharma veteran who took over as GSK ’s head of R&D last year. (Source: Forbes.com Healthcare News)
Source: Forbes.com Healthcare News - December 3, 2018 Category: Pharmaceuticals Authors: Matthew Herper, Forbes Staff Source Type: news

Janssen Affiliate Cilag GmbH International Enters Worldwide Collaboration and License Agreement with argenx for Cancer Immunotherapy Cusatuzumab
(Source: Johnson and Johnson)
Source: Johnson and Johnson - December 3, 2018 Category: Pharmaceuticals Source Type: news

South Africa: Youth Is No Protection Against Breast Cancer
[Daily Maverick] Think breast cancer is something only older women have to worry about? Think again. Experts say there are no age restrictions to this cancer - but that social support can mean the difference between life and death. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - December 3, 2018 Category: African Health Source Type: news

Janssen Affiliate Cilag GmbH International Enters Worldwide Collaboration and License Agreement with argenx for Cancer Immunotherapy Cusatuzumab
Addition of investigational antibody cusatuzumab to robust oncology pipeline reflects Janssen's commitment to advance innovative therapies for blood cancers where unmet medical needs remain UG, Switzerland, December 3, 2018 -- (Healthcare Sales & Market... Biopharmaceuticals, Oncology, Licensing Cilag, argenx BVBA, argenx SE, cusatuzumab (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - December 3, 2018 Category: Pharmaceuticals Source Type: news

GSK buys Tesaro for $5.1bn to boost cancer drugs
Shares lose 7 per cent on news of drugmaker’s first big acquisition under Emma Walmsley (Source: FT.com - Drugs and Healthcare)
Source: FT.com - Drugs and Healthcare - December 3, 2018 Category: Pharmaceuticals Source Type: news

GSK to boost cancer drugs pipeline with $5.1bn Tesaro purchase
Deal for US group will be first major acquisition under Emma Walmsley (Source: FT.com - Drugs and Healthcare)
Source: FT.com - Drugs and Healthcare - December 3, 2018 Category: Pharmaceuticals Source Type: news