ESR1-Driven Resistance to CDK4/6 Inhibitors in Breast Cancer Thwarted by SERDs
(MedPage Today) -- Mutations in ESR1 do not appear to confer breast cancer resistance to cyclin-dependent kinase (CDK)4/6 inhibitors, an analysis of clinical practice data suggested. Patients with metastatic hormone receptor-positive breast cancer... (Source: MedPage Today OB/GYN)
Source: MedPage Today OB/GYN - April 25, 2024 Category: OBGYN Source Type: news

No Best Nutrition Strategy for Most Preemies Waiting to Breastfeed
(MedPage Today) -- For preterm infants awaiting the chance to breastfeed, none of the common methods of nutritional support emerged a clear winner in head-to-head comparisons in the DIAMOND trial. For infants born between 32 and 35 weeks 6 days... (Source: MedPage Today OB/GYN)
Source: MedPage Today OB/GYN - April 24, 2024 Category: OBGYN Source Type: news

High-Dose Vit A Fails Again for Serious Lung Disease in Premature Infants
(MedPage Today) -- High-dose enteral vitamin A supplementation in the early postnatal period was safe but failed to reduce the likelihood of moderate or severe bronchopulmonary dysplasia in extremely low birthweight (ELBW) infants, a randomized... (Source: MedPage Today OB/GYN)
Source: MedPage Today OB/GYN - April 24, 2024 Category: OBGYN Source Type: news

FDA Greenlights Imaging Agent to Detect Residual Cancer After Lumpectomy
(MedPage Today) -- The FDA approved pegulicianine (LumiSight) as an optical imaging agent for detecting residual cancer after breast-conserving surgery (BCS). The approval stipulates use of pegulicianine with the Lumicell Direct Visualization... (Source: MedPage Today OB/GYN)
Source: MedPage Today OB/GYN - April 18, 2024 Category: OBGYN Source Type: news

Doc Fired After Deaths; Mass Shooting Blamed on Abortion Law; Record Drug Shortages
(MedPage Today) -- Note that some links may require registration or subscription. Ronald Daniel, MD, was fired following a maternal and infant death 2 weeks apart late last year at Woodhull Medical Center in New York City. (New York Times) Meanwhile... (Source: MedPage Today OB/GYN)
Source: MedPage Today OB/GYN - April 12, 2024 Category: OBGYN Source Type: news

New CDC Alert; Trump Disses Abortion Judgment; $10 Billion Long COVID 'Moonshot'
(MedPage Today) -- Note that some links may require registration or subscription. CDC will send a mass alert about counterfeit Botox injections that have already hospitalized at least four people. (NBC News) Former President Trump said Arizona... (Source: MedPage Today OB/GYN)
Source: MedPage Today OB/GYN - April 11, 2024 Category: OBGYN Source Type: news

Justice Department Issues Final Rule to End the 'Gun Show Loophole'
(MedPage Today) -- The "gun show loophole" that allowed some buyers to purchase guns without going through a background check is now history thanks to a final rule published Thursday by the Justice Department. "Under this regulation, it will not... (Source: MedPage Today OB/GYN)
Source: MedPage Today OB/GYN - April 11, 2024 Category: OBGYN Source Type: news

Acetaminophen Use in Pregnancy Not Linked With Autism, ADHD
(MedPage Today) -- Taking acetaminophen (Tylenol) during pregnancy was not associated with the development of autism or attention deficit-hyperactivity disorder (ADHD) in children, a large Swedish nationwide cohort study found. Models without... (Source: MedPage Today OB/GYN)
Source: MedPage Today OB/GYN - April 9, 2024 Category: OBGYN Source Type: news

D-Mannose Fails to Prevent Recurrent UTIs
(MedPage Today) -- D-mannose did not reduce the proportion of women with recurrent urinary tract infection (UTI), the randomized, placebo-controlled MERIT trial showed. Over the 6-month study period, 51% of women taking 2-g D-mannose powder daily... (Source: MedPage Today OB/GYN)
Source: MedPage Today OB/GYN - April 8, 2024 Category: OBGYN Source Type: news

Can Late-Stage Cancer Incidence Serve as an Endpoint for Screening Trials?
(MedPage Today) -- SAN DIEGO -- While using an endpoint of late-stage cancer incidence may be a suitable alternative to cancer-specific mortality for some cancers in screening trials, it doesn't work for others, researchers said here. A systematic... (Source: MedPage Today OB/GYN)
Source: MedPage Today OB/GYN - April 8, 2024 Category: OBGYN Source Type: news

More Evidence Ties Tumor Infiltrating Lymphocytes to TNBC Outcomes
(MedPage Today) -- Higher levels of tumor infiltrating lymphocytes (TILs) in triple-negative breast cancer (TNBC) not treated with systemic therapy correlated with significantly better survival, according to a retrospective study of an international... (Source: MedPage Today OB/GYN)
Source: MedPage Today OB/GYN - April 2, 2024 Category: OBGYN Source Type: news

Obesity in Pregnancy: Do Guidelines Recommend Too Much Weight Gain?
(MedPage Today) -- Pregnancy weight gain below the current minimum recommended by the U.S. Institute of Medicine (IOM) for obese patients did not appear to increase their risk for maternal and fetal complications and was linked to reduced risk... (Source: MedPage Today OB/GYN)
Source: MedPage Today OB/GYN - April 1, 2024 Category: OBGYN Source Type: news

Court Rules Against Pharmacist Who Refused Emergency Contraception Prescription
(MedPage Today) -- The Minnesota Court of Appeals has ruled that a pharmacist who refused to provide emergency contraceptives to a customer because of his personal beliefs engaged in discrimination. The three-judge panel ruled Monday that pharmacist... (Source: MedPage Today OB/GYN)
Source: MedPage Today OB/GYN - March 30, 2024 Category: OBGYN Source Type: news

IG Live March 29: Maternal Mortality Remains 'Unacceptably High'
(MedPage Today) -- Despite being a high-income country, the U.S. has double the maternal death rate of most other developed nations, with racial disparities exacerbating the crisis. In an observational study published in JAMA in 2023, researchers... (Source: MedPage Today OB/GYN)
Source: MedPage Today OB/GYN - March 28, 2024 Category: OBGYN Source Type: news

Supreme Court Appears Skeptical of Challenge to Abortion Pill Access
(MedPage Today) -- The Supreme Court seemed likely to preserve access to the widely used abortion pill mifepristone (Mifeprex), in the court's first abortion case since it overturned Roe v. Wade 2 years ago. During oral arguments on Tuesday, justices... (Source: MedPage Today OB/GYN)
Source: MedPage Today OB/GYN - March 26, 2024 Category: OBGYN Source Type: news