Advances in Cancer Prevention Lecture 2018: Successes and Challenges of Vaccines to Prevent HPV-associated Cancers
The Annual Advances in Cancer Prevention Lecture is sponsored by the Cancer Prevention Fellowship Program (CPFP) within the Division of Cancer Prevention (DCP) at NCI. It is also part of the course offerings of the annual NCI Summer Curriculum in Cancer Prevention, but is open to the entire NIH community and general public. This annual lecture addresses current challenges and/or approaches used by investigators to address gaps, advance science, and promote the application of successful strategies in the field of cancer prevention and control. NIH Distinguished Investigator and Deputy Chief of the Laboratory of Cellular Onc...
Source: Videocast - All Events - May 24, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video

Sounding the Alarm and Putting Out the Fire: New Mechanistic Insights into Inflammation Triggered by Invasive Infection
NIH Director ’ s Wednesday Afternoon Lecture Series The Lieberman laboratory studies cytotoxic T lymphocytes and their role in infection and tumor immunity. They study the molecular pathways used by killer lymphocytes and their cytotoxic granule proteases, called granzymes, and pore-forming proteins, perforin and granulysin, to induce programmed cell death. They have defined a caspase-independent programmed cell death pathway activated by granzyme A. Recent work has identified an unexpected role for granzymes and granulysin in protection against bacteria and parasites. They recently uncovered the molecular basis for ...
Source: Videocast - All Events - May 23, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video

4 Awesome Discoveries You Probably Didn't Hear About This Week - Episode 1
Your weekly briefing on the latest discoveries you might not hear about anywhere else, all with funding from the National Science Foundation. This week: 1. Finding cancer through the eye of a butterfly 2. Killer whales in rivers? Get used to it. 3. An "everything-repellent" coating ...This is an NSF Multimedia Gallery item. (Source: NSF Multimedia Gallery)
Source: NSF Multimedia Gallery - May 19, 2018 Category: Science Source Type: video

Targeting Lineage Restricted Oncoproteins in Childhood Cancers
CCR Eminent lecture series This monthly lecture series has been established to bring in prominent speakers to stimulate discussion of cutting-edge research areas and facilitate exchange of ideas, possibly leading to fruitful collaborations.Air date: 5/21/2018 3:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - May 15, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video

Mechanisms of breast cancer metastasis and targeting opportunities
Director's Seminar Series Cancer metastasis is the primary cause of cancer-associated death. Current treatment strategies have been largely ineffective in patients with metastatic disease. It ’ s becoming clear that the tumor microenvironment plays an essential role in the metastatic process. We investigate the critical inflammatory and immune suppressive mediators that promote metastatic cancer cell survival and colonization at distant organ site. Our work provides insights for metastatic biology and therapeutic options aimed at targeting metastatic breast cancer.Air date: 5/18/2018 12:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - May 15, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video

Cancer lurking in tissue could be more easily found when looking through a butterfly's eye.
Researchers have developed a surgical camera inspired by the eye of the morpho butterfly. Connected to surgical goggles, it lets surgeons see infrared signals given off by tumor-binding dyes so the surgeon can remove all of the cancerous tissue.This is an NSF Multimedia Gallery item. (Source: NSF Multimedia Gallery)
Source: NSF Multimedia Gallery - May 4, 2018 Category: Science Source Type: video

Jonathan E. Rosenberg, MD - Strengthening Our Grip on Immuno-Oncology in Genitourinary Cancers: Understanding Science Through Stories
Strengthening Our Grip on Immuno-Oncology in Genitourinary Cancers: Understanding Science Through Stories (Source: PeerView CME/CE Video Podcast - Oncology)
Source: PeerView CME/CE Video Podcast - Oncology - April 27, 2018 Category: Cancer & Oncology Authors: PVI, PeerView Institute for Medical Education Tags: Science, Medicine Source Type: video

Accelerating Rural Cancer Control Research Meeting (Day 2)
The Accelerating Rural Cancer Control Research (ARCC) Meeting aims to identify gaps in rural cancer control research and practice, build partnerships across various stakeholder groups to address challenges and disseminate solutions, and to highlight and identify approaches to address shared and competing priorities of providers, health systems, researchers, patients, and communities.For more information go tohttps://cancercontrol.cancer.gov/research-emphasis/meetings/arcc-meeting.htmlAir date: 5/31/2018 8:30:00 AM (Source: Videocast - All Events)
Source: Videocast - All Events - April 27, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video

Accelerating Rural Cancer Control Research Meeting (Day 1)
The Accelerating Rural Cancer Control Research (ARCC) Meeting aims to identify gaps in rural cancer control research and practice, build partnerships across various stakeholder groups to address challenges and disseminate solutions, and to highlight and identify approaches to address shared and competing priorities of providers, health systems, researchers, patients, and communities.For more information go tohttps://cancercontrol.cancer.gov/research-emphasis/meetings/arcc-meeting.htmlAir date: 5/30/2018 9:00:00 AM (Source: Videocast - All Events)
Source: Videocast - All Events - April 27, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video

Butterfly cam catches cancer!
NSFfunded researchers at the University of Illinois at Urbana-Champaign and Washington University in St. Louis have developed a surgical camera inspired by the eye of the Morpho butterfly to more accurately find lurking cancer.This is an NSF Multimedia Gallery item. (Source: NSF Multimedia Gallery)
Source: NSF Multimedia Gallery - April 26, 2018 Category: Science Source Type: video

Ezra Cohen, MD, FRCPC, FASCO - Solving the Multimodal Puzzle of Head & Neck Cancer in the Immunotherapy Era: How Evidence is Driving Practice Changes
Solving the Multimodal Puzzle of Head & Neck Cancer in the Immunotherapy Era: How Evidence is Driving Practice Changes (Source: PeerView CME/CE Video Podcast - Oncology)
Source: PeerView CME/CE Video Podcast - Oncology - April 25, 2018 Category: Cancer & Oncology Authors: PVI, PeerView Institute for Medical Education Tags: Science, Medicine Source Type: video

CCR Grand Rounds
NCI ’ s Center for Cancer Research (CCR) Grand Rounds is a weekly lecture series addressing current research in clinical and molecular oncology. Speakers are leading national and international researchers and clinicians.Air date: 6/15/2018 12:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - April 25, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video

CCR Grand Rounds Special Oncology Nursing Lecture
NCI ’ s Center for Cancer Research (CCR) Grand Rounds is a weekly lecture series addressing current research in clinical and molecular oncology. Speakers are leading national and international researchers and clinicians.Air date: 6/8/2018 12:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - April 24, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video

CCR Grand Rounds
NCI ’ s Center for Cancer Research (CCR) Grand Rounds is a weekly lecture series addressing current research in clinical and molecular oncology. Speakers are leading national and international researchers and clinicians.Air date: 5/11/2018 12:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - April 24, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video

DNA Repair Interest Group - A comprehensive repertoire of mutational signatures in human cancer
DNA Repair Interest Group videoconferenceAir date: 6/19/2018 12:30:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - April 23, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video

Why don't we get more cancer: The importance of ECM Chromatin interactions in tissue-specificity and breast cancer
NCI ’ s Center for Cancer Research (CCR) Grand Rounds is a weekly lecture series addressing current research in clinical and molecular oncology. Speakers are leading national and international researchers and clinicians.Air date: 4/27/2018 12:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - April 19, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video

Andrew H. Ko, MD - The Quest to Win Through Science in Pancreatic Cancer: From Sequencing Current Options to Testing Novel Approaches
The Quest to Win Through Science in Pancreatic Cancer: From Sequencing Current Options to Testing Novel Approaches (Source: Peerview CME/CE Video Podcast - Internal Medicine International)
Source: Peerview CME/CE Video Podcast - Internal Medicine International - April 18, 2018 Category: Internal Medicine Authors: PVI, PeerView Institute for Medical Education Tags: Science, Medicine Source Type: video

Asian American Cancer Health Disparities: Updates and Innovations
The objectives of Dr. Nguyen ’ s presentation will include: Know about the incidence and mortality rates of cancer among Asian AmericansKnow about cancer prevention and early detection behaviors and practices among Asian AmericansLearn about recent innovative interventions to address cancer prevention and early detection among Asian Americans Dr. Nguyen is the Director of the Asian American Research Center on Health (ARCH) which has over 40 individual and organizational members dedicated to improving the health of Asian Americans. He is also the Co-Director of the UCSF Multi-Ethnic Health Equity Center (MERC), UCSF D...
Source: Videocast - All Events - April 17, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video

Epigenetic genome control by RNA-based mechanisms
NCI ’ s Center for Cancer Research (CCR) Grand Rounds is a weekly lecture series addressing current research in clinical and molecular oncology. Speakers are leading national and international researchers and clinicians.Air date: 4/20/2018 12:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - April 11, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video

A Changing Picture of Prostate Cancer: Advances in Imaging
NCI ’ s Center for Cancer Research (CCR) Grand Rounds Peter L. Choyke, M.D., F.A.C.R. Dr. Choyke directs the NCI Molecular Imaging Program. His research interests include the translation of molecular imaging methods, such as MRI, optical and radionuclide/PET into the clinic. His research includes novel methods of detecting ovarian cancer, prostate cancer, angiogenesis, lymphangiogenesis, cancer cell receptor imaging and treatment, cell tracking, and exploration of unique animal models of cancer.Air date: 4/13/2018 12:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - April 9, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video

T Cell Memory and Exhaustion
Immunonology IG Seminar Dr. Rafi Ahmed is the Georgia Research Alliance Professor of Microbiology and Immunology, and Director of the Emory Vaccine Center at Emory University School of Medicine in Atlanta, GA. His research efforts are directed towards: 1. Understanding the mechanisms of immunological memory and using this knowledge to develop new and more effective vaccines. 2. Defining the mechanisms of T cell exhaustion during chronic viral infections and cancer and developing strategies for restoring function in exhausted T cells. Dr. Ahmed is a member of the National Academy of Sciences and the National Academy of Medi...
Source: Videocast - All Events - April 9, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video

Zebrafish models of metastasis
NCI ’ s Center for Cancer Research (CCR) Grand Rounds is a weekly lecture series addressing current research in clinical and molecular oncology. Speakers are leading national and international researchers and clinicians.Air date: 4/6/2018 12:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - April 5, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video

Naiyer Rizvi, MD - Moving in Leaps and Bounds Towards Precision Immuno-Oncology: Latest Biomarker Strategies to Guide Patient Selection and Maximize the Potential of Cancer Immunotherapies
Moving in Leaps and Bounds Towards Precision Immuno-Oncology: Latest Biomarker Strategies to Guide Patient Selection and Maximize the Potential of Cancer Immunotherapies (Source: PeerView CME/CE Video Podcast - Oncology)
Source: PeerView CME/CE Video Podcast - Oncology - April 4, 2018 Category: Cancer & Oncology Authors: PVI, PeerView Institute for Medical Education Tags: Science, Medicine Source Type: video

Skin resident T cells in human health and disease
Immunology IG Seminar Dr. Clark attended Caltech as an undergraduate, where she was told to avoid a career in medicine. Despite this excellent advice, she completed the M.D./Ph.D. program at Harvard Medical School and now serves as the Shing-Yiu Yip and Cecilia M. Hepp Associate Professor of Dermatology at Harvard Medical School and the Director of the NIAMS P30 funded Human Skin Disease Resource Center. Her research focuses on the study of human T cell responses in skin and other peripheral tissues, including T cell function in healthy skin, impaired T cell migration and responses in skin cancer, and maladaptive T cell ac...
Source: Videocast - All Events - April 4, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video

Immunonology IG Seminar: “ Skin resident T cells in human health and disease ”
Dr. Clark attended Caltech as an undergraduate, where she was told to avoid a career in medicine. Despite this excellent advice, she completed the M.D./Ph.D. program at Harvard Medical School and now serves as the Shing-Yiu Yip and Cecilia M. Hepp Associate Professor of Dermatology at Harvard Medical School and the Director of the NIAMS P30 funded Human Skin Disease Resource Center. Her research focuses on the study of human T cell responses in skin and other peripheral tissues, including T cell function in healthy skin, impaired T cell migration and responses in skin cancer, and maladaptive T cell activation in inflammato...
Source: Videocast - All Events - April 3, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video

Mini Symposium on Breast Cancer Metastasis
The mini symposium features two speakers from Einstein College School of Medicine, Dr. John Condeelis and Dr. Maya Oktay, who will talk about imaging and treatment of breast cancer metastasis. Title of the talks: “ High resolution imaging of the mechanism of how breast cancer initiates and sustains systemic dissemination ” by Dr. John Condeelis “ The impact of chemotherapy on the Tumor Micro-Environment of Metastasis (TMEM)-mediated breast cancer cell dissemination and who may be affected the most ” by Dr. Maya OktayAir date: 4/4/2018 9:00:00 AM (Source: Videocast - All Events)
Source: Videocast - All Events - March 28, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video

Annual Advances in Cancer Prevention Lecture 2018
The Annual Advances in Cancer Prevention Lecture is sponsored by the Cancer Prevention Fellowship Program (CPFP) within the Division of Cancer Prevention (DCP) at NCI. It is also part of the course offerings of the annual NCI Summer Curriculum in Cancer Prevention, but is open to the entire NIH community and general public. This annual lecture addresses current challenges and/or approaches used by investigators to address gaps, advance science, and promote the application of successful strategies in the field of cancer prevention and control. NIH Distinguished Investigator and Deputy Chief of the Laboratory of Cellular Onc...
Source: Videocast - All Events - March 26, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video

CC Grand Rounds: 1) Localized Bladder Cancer: Management, Challenges, and Clinical Trials and 2) Advanced and Metastatic Bladder Cancer: Management, Challenges, and Clinical Trials
For more information go tohttp://www.cc.nih.gov/about/news/grcurrent.htmlAir date: 4/18/2018 12:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - March 26, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video

Contemporary Clinical Medicine: Great Teachers: Breast Cancer in the Age of Precision Cancer Medicine
For more information go tohttp://www.cc.nih.gov/about/news/grcurrent.htmlAir date: 4/11/2018 12:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - March 26, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video

Autoimmunity, Cancer and Immunology (Day 2)
This meeting will focus on 2 issues and will include speakers from the NIH intramural and extramural communities: Understanding the biology of immune-related adverse events which have occurred in cancer patients being treated with immunotherapies and how that might inform the study of autoimmune disease. Defining the potential for the study of autoimmune disease to lead to greater understanding of the treatment and management of immune-related adverse events during and following cancer therapies.For more information go tohttps://ncifrederick.cancer.gov/events/CicAutoimmune2018/default.aspAir date: 3/23/2018 8:00:00 AM (S...
Source: Videocast - All Events - March 19, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video

Autoimmunity, Cancer and Immunology (Day 1)
This meeting will focus on 2 issues and will include speakers from the NIH intramural and extramural communities: Understanding the biology of immune-related adverse events which have occurred in cancer patients being treated with immunotherapies and how that might inform the study of autoimmune disease. Defining the potential for the study of autoimmune disease to lead to greater understanding of the treatment and management of immune-related adverse events during and following cancer therapies.For more information go tohttps://ncifrederick.cancer.gov/events/CicAutoimmune2018/default.aspAir date: 3/22/2018 8:00:00 AM (S...
Source: Videocast - All Events - March 19, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video

PD-1 Cancer Immunotherapy
NCI Center for Cancer Research Eminent Lecture Series Gordon J. Freeman, PhD works in the Department of Medical Oncology at Dana-Farber Cancer Institute and is Professor of Medicine at Harvard Medical School. Dr. Freeman earned his BA in Biochemistry and Molecular Biology, and PhD in Microbiology and Molecular Genetics from Harvard University. His research has identified the major pathways that control the immune response by inhibiting T cell activation (PD-1/PD-L1 and B7-2/CTLA-4) or stimulating T cell activation (B7-2/CD28). In 2000, Dr. Freeman discovered PD-L1 and PD-L2, and showed they were ligands for PD-1, thus def...
Source: Videocast - All Events - March 16, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video

NIH Protocol Navigation Training: Common Rule Issues with Tissues
The objectives of this talk are:• To describe the new provisions in the Final Rule that pertain to biospecimens and associated data;• To provide background on the multiple proposals to revise the Common Rule that were published in the ANPRM and the Notice of Proposed Rulemaking (NPRM), but which, ultimately, were withdrawn from the Final Rule, including suggestions to revise the definition of human subject and to render all research uses of human biological tissue human subject research;• To discuss the potential impact on policy and practice of the new provisions in the Final Rule that regulate the colle...
Source: Videocast - All Events - March 13, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video

Cancer and other infectious diseases better watch out for DETECTR, a powerful new DNA-targeted diagn
A diagnostic system called the DNA Endonuclease Targeted CRISPR Trans Reporter, or DETECTR, could make possible quick and easy point-of-care detection of even small amounts of DNA in clinical samples. Using DETECTR, scientists were able to demonstrate accurate detection of the "high-risk" HPV types ...This is an NSF Multimedia Gallery item. (Source: NSF Multimedia Gallery)
Source: NSF Multimedia Gallery - March 6, 2018 Category: Science Source Type: video

From Germline Genetics to Function: Making Sense of Genome-Wide Association Studies for Pancreatic Cancer Risk
NIH Directors Seminar Series Pancreatic ductal adenocarcinoma (PDAC) is the third leading cause of cancer-related deaths in the United States and the seventh world-wide. This seminar will discuss results from genome-wide association studies (GWAS), conducted within the NCI-led Pancreatic Cancer Cohort Consortium. This collaborative effort has identified over 20 common pancreatic cancer risk loci. Genomic and functional characterization of a subset of these loci will be presented. These examples highlight different molecular mechanisms underlying cancer risk and genes found to be important for a wide range of processes incl...
Source: Videocast - All Events - March 1, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video

Pathway Directed Treatment Strategies in Kidney Cancer
NCI ’ s Center for Cancer Research (CCR) Grand Rounds is a weekly lecture series addressing current research in clinical and molecular oncology. Speakers are leading national and international researchers and clinicians.Air date: 3/16/2018 12:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - February 27, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video

The Science of Patient-Centered Research: Enhancing Our Understanding of the Impact of Cancer and Its Treatment
NCI ’ s Center for Cancer Research (CCR) Grand Rounds is a weekly lecture series addressing current research in clinical and molecular oncology. Speakers are leading national and international researchers and clinicians.Air date: 3/9/2018 12:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - February 27, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video

CSSI Science Day 2018
The Purpose of the meeting/conference is to convene and engage CSSI OD Staff as well as CSSI Program/Initiative stakeholders to share their ideas and programmatic advancements to hopefully stimulate new and exciting pilot projects, research ideas, and ventures. This annual meeting will be supported by CSSI OD Offices which includes the Office of Cancer Clinical Proteomics Research as well as the Knowledge Management and Special Projects Branch. CSSI goals and mission are designed to fulfill a fundamental need in the cancer research community by finding and enabling investigator driven, research and team oriented, technolog...
Source: Videocast - All Events - February 26, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video

Omics Approaches to Cancer and Health
NCI's Center for Cancer Research (CCR) Eminent Lectures This monthly lecture series has been established to bring in prominent speakers to stimulate discussion of cutting-edge research areas and facilitate exchange of ideas, possibly leading to fruitful collaborations.Air date: 2/26/2018 3:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - February 26, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video

RNA Methylation in Gene Expression Regulation
NCI's Center for Cancer Research (CCR) Grand Rounds Chuan He, Ph.D., is the John T. Wilson Distinguished Service Professor in the Department of Chemistry, Department of Biochemistry and Molecular Biology, and Institute for Biophysical Dynamics at the University of Chicago. He was born in P. R. China in 1972 and received his B.S. (1994) from the University of Science and Technology of China. He received his Ph.D. degree from Massachusetts Institute of Technology in chemistry in 2000 with Professor Stephen J. Lippard. After being trained as a Damon-Runyon postdoctoral fellow with Professor Gregory L. Verdine at Harvard Unive...
Source: Videocast - All Events - February 20, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video

Biowulf Seminar Series: How to build a dog in 2,392,715,236 simple steps
Biowulf Seminar Series The Biowulf seminar series continues with talks by Biowulf users. The first such seminar features Heidi Parker, the Senior Staff Scientist for the Dog Genome Project at NHGRI The NHGRI Dog Genome Project at NIH and focuses on the genetics of health and body structure in the domestic dog. We are particularly interested in the variation represented in individual dog breeds, which allows us to focus on locating genes involved in both canine cancer and the morphologic traits. Our research yields not only an understanding of how genes interact to create the modern dog breeds we see today and how we can ke...
Source: Videocast - All Events - February 16, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video

NCI Post-Treatment Surveillance Workshop - March 2018 (Day 2)
To discuss issues in post treatment surveillance given the current advances in imaging and in vitro diagnostics. Specific discussions will occur in Breast, Colon, NSCLS, Colorectal Cancer and Testicular cancer. Identify and prioritize histologies and tools that are most suitable to be evaluated in this setting, in NCTN and NCORP clinical trials.Air date: 3/27/2018 8:00:00 AM (Source: Videocast - All Events)
Source: Videocast - All Events - February 15, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video

NCI Post-Treatment Surveillance Workshop - March 2018 (Day 1)
To discuss issues in post treatment surveillance given the current advances in imaging and in vitro diagnostics. Specific discussions will occur in Breast, Colon, NSCLS, Colorectal Cancer and Testicular cancer. Identify and prioritize histologies and tools that are most suitable to be evaluated in this setting, in NCTN and NCORP clinical trials.Air date: 3/26/2018 8:00:00 AM (Source: Videocast - All Events)
Source: Videocast - All Events - February 15, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video

Mechanistic basis of cancer immunotherapy
NIH Director's Wednesday Afternoon Lecture Series My group ’ s long interest in understanding the cellular mechanisms of the immune response has increasingly focused on the problem of cancer immunology and immunotherapy. We have now established an entire department devoted to this effort, and postdocs in my group seek to understand how checkpoint inhibitors (eg anti-PD-L1), vaccines, immune agonists and their combinations work to produce durable anti-cancer responses.For more information go tohttps://oir.nih.gov/wals/2017-2018/Air date: 4/18/2018 3:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - February 14, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video

Of bones, brain, and fat: macrophages and the control of homeostasis
NIH Director's Wednesday Afternoon Lecture Series Over the past ten years, we have investigated the developmental origin and homeostasis of macrophages and the related cell types monocytes and dendritic cells. These cells play a major role in development, homeostasis and diverse types of cancer and can either restrain or promote cancer progression and metastasis. The Geissmann lab is now building on previous work to investigate mechanisms by which tissue macrophages may control tissue growth and metabolism and whether these same mechanisms play a role in cancer initiation and development.For more information go tohttps://o...
Source: Videocast - All Events - February 14, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video

HPV VLPs: Nature ’ s Nanoparticles for Prevention and Treatment of Cancer
NCI ’ s Center for Cancer Research (CCR) Grand Rounds Dr. John Schiller graduated from the University of Wisconsin-Madison with a B.S. in molecular biology in 1975. In 1982, he received a Ph.D. from the Department of Microbiology of the University of Washington in Seattle, then joined the NCI Laboratory of Cellular Oncology as a National Research Service Award postdoctoral fellow in 1983. Dr. Schiller became a senior staff fellow in the Laboratory of Cellular Oncology in 1986 and a senior investigator in 1992. He became chief of the Neoplastic Disease Section of the lab in 1998, deputy lab chief in 2000 and designate...
Source: Videocast - All Events - February 5, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video

Mitochondria control of physiology and disease: beyond ATP
NIH Director ’ s Wednesday Afternoon Lecture Series For decades, the mitochondria have been primarily viewed as biosynthetic and bioenergetic organelles generating metabolites for the production of macromolecules and ATP, respectively. Our work has elucidated that mitochondria have a third distinct role whereby they release reactive oxygen species (ROS) and metabolites such as L-2-hydroxyglutarate to initiate physiological and pathological processes including hypoxic activation of HIFs, cellular differentiation, T cell activation and cancer cell proliferation. Thus, mitochondria function as signaling organelles.For m...
Source: Videocast - All Events - February 5, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video

A comprehensive repertoire of mutational signatures in human cancer
DNA Repair Interest Group videoconferenceAir date: 6/19/2018 12:30:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - January 30, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video

Proteogenomics of Breast Cancer
NCI's Center for Cancer Research (CCR) Grand Rounds Dr. Matthew Ellis ’ s clinical and basic research focuses on breast cancer. He has developed neoadjuvant endocrine therapy as an alternative to chemotherapy for promoting breast-conserving therapy in postmenopausal women with ER+ HER2- stage 2 and 3 disease. He developed and validated the Ki67 proliferation marker-based Preoperative Endocrine Prognostic Index which is now undergoing a large validation study (the ALTERNATE study). These clinical studies have provided the clinical context and tumor specimens for seminal investigations into the ER+ breast cancer somati...
Source: Videocast - All Events - January 30, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video

National Cancer Advisory Board (NCAB) Virtual Meeting - February 2018
The 8th Virtual Meeting of the National Cancer Advisory Board (NCAB)Air date: 2/13/2018 1:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - January 25, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video