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TAT International Congress 2018: The home of phase I in oncology
(European Society for Medical Oncology) The TAT (Targeted Anticancer Therapies) International Congress 2018 will take place in Paris, France where around 450 attendees from all over the world are expected to join what is renowned to be 'the home of phase I in oncology.' (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - February 22, 2018 Category: Cancer & Oncology Source Type: news

NEJM reports positive results for larotrectinib against TRK-fusion cancer
(University of Colorado Anschutz Medical Campus) 55 patients representing 17 cancer types tested positive for TRK fusion and were treated with larotrectinib. Overall response rate was 75 percent. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - February 22, 2018 Category: Cancer & Oncology Source Type: news

How spacecraft testing enabled bone marrow research
(NASA/Goddard Space Flight Center) In the 1970s, a NASA employee stepped up to a challenge posed by the National Institutes of Health or NIH: to freeze bone marrow. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - February 22, 2018 Category: Cancer & Oncology Source Type: news

Prestigious AGA Recognition Awards presented to GI leaders
(American Gastroenterological Association) The American Gastroenterological Association (AGA) has announced the 2018 recipients of the annual recognition awards, given in honor of outstanding contributions and achievements in gastroenterology. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - February 22, 2018 Category: Cancer & Oncology Source Type: news

Low-calorie diet enhances intestinal regeneration after injury
(University of Pennsylvania) Animals fed restricted-calorie diets are better able to regenerate numerous tissues after injury. A new study led by University of Pennsylvania researchers pinpoints the cell responsible for these improved regenerative abilities in the intestines. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - February 22, 2018 Category: Cancer & Oncology Source Type: news

New strategy to target transcription factor STAT5 to combat leukaemia
(University of Veterinary Medicine -- Vienna) Acute myeloid leukaemia is the most common type of acute cancer of the blood and bone marrow in adults. AML progresses quickly and only 26 percent of the patients survive longer than 5 years as resistance against established treatments arises. The most common molecular cause is FLT3 mutations, which result in hyper-activation of STAT5. A researcher consortium now reports on an early preclinical development to target STAT5 directly, which cooperates well with existing therapies. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - February 22, 2018 Category: Biology Source Type: news

Study uncovers secrets of cancer-resistant naked mole rat
Researchers from the University identified a unique characteristic behind a cellular process that may allow the rodents to fight both cancer and the effects of aging. (Source: the Mail online | Health)
Source: the Mail online | Health - February 22, 2018 Category: Consumer Health News Source Type: news

ER-Negative Isolated Locoregional Recurrence Benefits From Chemotherapy
Patients with ER-negative, but not ER-positive, isolated locoregional recurrence after unilateral breast cancer derive significant benefit from chemotherapy. (Source: CancerNetwork)
Source: CancerNetwork - February 22, 2018 Category: Cancer & Oncology Authors: Dave Levitan Tags: Breast Cancer News Source Type: news

Cancer detection: Seeking signals in blood
(Source: ScienceNOW)
Source: ScienceNOW - February 22, 2018 Category: Science Authors: Kalinich, M., Haber, D. A. Tags: Immunology perspective Source Type: news

Cancer organoids to model therapy response
(Source: ScienceNOW)
Source: ScienceNOW - February 22, 2018 Category: Science Authors: Kelly, P. N. Tags: Medicine, Diseases twis Source Type: news

SEEK and you may find cancer earlier
(Source: ScienceNOW)
Source: ScienceNOW - February 22, 2018 Category: Science Authors: Kiberstis, P. A. Tags: Medicine, Diseases twis Source Type: news

Detection and localization of surgically resectable cancers with a multi-analyte blood test
Earlier detection is key to reducing cancer deaths. Here, we describe a blood test that can detect eight common cancer types through assessment of the levels of circulating proteins and mutations in cell-free DNA. We applied this test, called CancerSEEK, to 1005 patients with nonmetastatic, clinically detected cancers of the ovary, liver, stomach, pancreas, esophagus, colorectum, lung, or breast. CancerSEEK tests were positive in a median of 70% of the eight cancer types. The sensitivities ranged from 69 to 98% for the detection of five cancer types (ovary, liver, stomach, pancreas, and esophagus) for which there are no sc...
Source: ScienceNOW - February 22, 2018 Category: Science Authors: Cohen, J. D., Li, L., Wang, Y., Thoburn, C., Afsari, B., Danilova, L., Douville, C., Javed, A. A., Wong, F., Mattox, A., Hruban, R. H., Wolfgang, C. L., Goggins, M. G., Dal Molin, M., Wang, T.-L., Roden, R., Klein, A. P., Ptak, J., Dobbyn, L., Schaefer, J Tags: Medicine, Diseases reports Source Type: news

Patient-derived organoids model treatment response of metastatic gastrointestinal cancers
We report on a living biobank of PDOs from metastatic, heavily pretreated colorectal and gastroesophageal cancer patients recruited in phase 1/2 clinical trials. Phenotypic and genotypic profiling of PDOs showed a high degree of similarity to the original patient tumors. Molecular profiling of tumor organoids was matched to drug-screening results, suggesting that PDOs could complement existing approaches in defining cancer vulnerabilities and improving treatment responses. We compared responses to anticancer agents ex vivo in organoids and PDO-based orthotopic mouse tumor xenograft models with the responses of the patients...
Source: ScienceNOW - February 22, 2018 Category: Science Authors: Vlachogiannis, G., Hedayat, S., Vatsiou, A., Jamin, Y., Fernandez-Mateos, J., Khan, K., Lampis, A., Eason, K., Huntingford, I., Burke, R., Rata, M., Koh, D.-M., Tunariu, N., Collins, D., Hulkki-Wilson, S., Ragulan, C., Spiteri, I., Moorcraft, S. Y., Chau, Tags: Medicine, Diseases reports Source Type: news

Queens Medical Associates Shares Insight for National Cancer Awareness...
Leading oncology and hematology practice provides tips on cancer prevention(PRWeb February 22, 2018)Read the full story at http://www.prweb.com/releases/2018/02/prweb15236048.htm (Source: PRWeb: Medical Pharmaceuticals)
Source: PRWeb: Medical Pharmaceuticals - February 22, 2018 Category: Pharmaceuticals Source Type: news

From Genes and Cells to Saving Lives: NEJM Reports Positive Results...
Basic science from University of Colorado Cancer Center leads to clinical trial results reported in New England Journal of Medicine: Of 55 patients with TRK-fusion cancer who progressed after...(PRWeb February 22, 2018)Read the full story at http://www.prweb.com/releases/2018/02/prweb15239492.htm (Source: PRWeb: Medical Pharmaceuticals)
Source: PRWeb: Medical Pharmaceuticals - February 22, 2018 Category: Pharmaceuticals Source Type: news

YouTuber dies of cancer after claiming veganism cured it
Mari Lopez, who ran the food channel at home in Houston, Texas with her niece Liz Johnson, told viewers she had rejected traditional treatment for breast cancer in favor of a 90-day juice cleanse. (Source: the Mail online | Health)
Source: the Mail online | Health - February 21, 2018 Category: Consumer Health News Source Type: news

Just one soft drink a day could increase cancer risk, study finds
Researchers hail ‘surprising’ findings about sugar after analysing more than 3,000 casesPeople who regularly consume at least one sugary soft drink a day, no matter the size of their waist, could be at increased risk of cancer, according to a new study.Researchers from Cancer Council Victoria and University of Melbourne studied more than 35,000 Australians who developed 3,283 cases of obesity-related cancers.Continue reading... (Source: Guardian Unlimited Science)
Source: Guardian Unlimited Science - February 21, 2018 Category: Science Authors: Australian Associated Press Tags: Sugar Soft drinks Health Cancer Obesity Melbourne Victoria Australia news Medical research Science Source Type: news

AHN's Forbes cancer center a glimpse of health system's future
Both AHN and UPMC, the two big health care providers in the Pittsburgh region, are putting more emphasis on community care, offering sophisticated treatment previously available at big-city hospitals. (Source: bizjournals.com Health Care:Biotechnology headlines)
Source: bizjournals.com Health Care:Biotechnology headlines - February 21, 2018 Category: Biotechnology Authors: Paul J. Gough Source Type: news

AHN's Forbes cancer center a glimpse of health system's future
Both AHN and UPMC, the two big health care providers in the Pittsburgh region, are putting more emphasis on community care, offering sophisticated treatment previously available at big-city hospitals. (Source: bizjournals.com Health Care:Pharmaceuticals headlines)
Source: bizjournals.com Health Care:Pharmaceuticals headlines - February 21, 2018 Category: Pharmaceuticals Authors: Paul J. Gough Source Type: news

After-effects not necessarily reduced with robotic prostate surgery
(Reuters Health) - Men with prostate cancer who get the gland removed may be just as likely to suffer after-effects like erectile dysfunction and urinary incontinence with robotic surgery as with other operations, a UK study suggests. (Source: Reuters: Health)
Source: Reuters: Health - February 21, 2018 Category: Consumer Health News Tags: healthNews Source Type: news

Perceived Narrowing of Racial Disparity in Prostate Cancer Outcomes Due to Screening
The observed narrowing of racial disparities in prostate cancer outcome since the advent of PSA screening is not as large as previously believed. (Source: CancerNetwork)
Source: CancerNetwork - February 21, 2018 Category: Cancer & Oncology Authors: Dave Levitan Tags: Genitourinary Cancers News Prostate Cancer Source Type: news

Lung cancer warning - why you should never ignore dizziness
CANCER symptoms can include changes to the body ’s normal processes. But, feeling dizzy could be a sign of lung cancer, Cancer Research UK warned. (Source: Daily Express - Health)
Source: Daily Express - Health - February 21, 2018 Category: Consumer Health News Source Type: news

First Look: Allegheny Health Network's new cancer center at Forbes
Work on the center has already begun. (Source: bizjournals.com Health Care:Physician Practices headlines)
Source: bizjournals.com Health Care:Physician Practices headlines - February 21, 2018 Category: American Health Authors: Paul J. Gough Source Type: news

Online Tool Aids Decision Making About Breast Cancer Treatment
Findings based on assessment of the interactive iCanDecide tool (Source: The Doctors Lounge - Oncology)
Source: The Doctors Lounge - Oncology - February 21, 2018 Category: Cancer & Oncology Tags: Gynecology, Oncology, Surgery, Journal, Source Type: news

Cigars and pipes tied to same risks as cigarettes
(Reuters Health) - Cigarettes are not the only type of tobacco products that can lead to premature death or fatalities from smoking-related cancers, a U.S. study confirms. (Source: Reuters: Health)
Source: Reuters: Health - February 21, 2018 Category: Consumer Health News Tags: healthNews Source Type: news

U.S. Tobacco Control Policies to Reduce Health Disparities (R01 Clinical Trial Optional
Funding to support observational or intervention research focused on reducing cancer health disparities in tobacco use in the United States. Specifically, this FOA is intended to stimulate scientific inquiry focused on innovative tobacco control policies. (Source: PHPartners.org)
Source: PHPartners.org - February 21, 2018 Category: International Medicine & Public Health Source Type: news

Billy Graham, 'America's Pastor' Dies at 99
Internationally known evangelist Billy Graham, a counselor to presidents had been treated for cancer, pneumonia and other ailments before his death at 99. (Source: WebMD Health)
Source: WebMD Health - February 21, 2018 Category: Consumer Health News Source Type: news

When you have kidney cancer...
There's one important thing to remember, when you've been diagnosed with kidney cancer. What is it?02/21/2018 (Source: Kidney Cancer Association)
Source: Kidney Cancer Association - February 21, 2018 Category: Urology & Nephrology Source Type: news

Medical News Today: How one enzyme could stop the spread of cancer
A study reveals that activation of the enzyme RIPK1 can trigger cell death in cancer cells poised to migrate by causing them to degrade their mitochondria. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - February 21, 2018 Category: Consumer Health News Tags: Cancer / Oncology Source Type: news

Can you vaccinate yourself against cancer?
Studies touting the benefits of cancer vaccines are emerging, but do those studies really show hope or just hype? Here's a look at the past, present and future of cancer vaccine research. (Source: CNN.com - Health)
Source: CNN.com - Health - February 21, 2018 Category: Consumer Health News Source Type: news

Cancer vaccines: Where do we stand?
Studies touting the benefits of cancer vaccines are emerging, but do those studies really show hope or just hype? Here's a look at the past, present and future of cancer vaccine research. (Source: CNN.com - Health)
Source: CNN.com - Health - February 21, 2018 Category: Consumer Health News Source Type: news

' Unrealistic Expectations' for Cancer Survivorship Care Plans'Unrealistic Expectations' for Cancer Survivorship Care Plans
In the current literature, there is limited evidence of benefit from survivorship care plans. Researchers are calling for a shift in the focus of current research.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - February 21, 2018 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

Kenya:MoH Partners With Johnson & Johnson to Aid Cancer Control Strategy
[Capital FM] Kisumu -The Ministry of Health has stepped up ongoing efforts to raise awareness on the National Cancer Control Strategy 2017-2022. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - February 21, 2018 Category: African Health Source Type: news

Doctors In China Lead Race To Treat Cancer By Editing Genes
More than a third of patients with cancer of the esophagus responded to experimental treatment in China with the gene-editing technique CRISPR. Several CRISPR studies are underway there.(Image credit: Yuhan Xu/NPR) (Source: NPR Health and Science)
Source: NPR Health and Science - February 21, 2018 Category: Consumer Health News Authors: Rob Stein Source Type: news

Woman's cancer ate away her ribs like 'a caterpillar'
In February 2012, Catherine Cook, 55, from Suffolk, began experiencing tight pains in her chest and shoulder, which intensified over the next six months. By June, she was in agony. (Source: the Mail online | Health)
Source: the Mail online | Health - February 21, 2018 Category: Consumer Health News Source Type: news

How is ovarian cancer detected? If you have the signs and symptoms take this test
OVARIAN cancer symptoms can be difficult to recognise, particularly in the early stages, but if you ’ve experienced bloating most days for the last three weeks, you may want to look out for other signs and consider visiting your GP for a test. (Source: Daily Express - Health)
Source: Daily Express - Health - February 21, 2018 Category: Consumer Health News Source Type: news

Roche to acquire Flatiron Health to accelerate industry-wide development and delivery of breakthrough medicines for patients with cancer
Roche (SIX: RO, ROG; OTCQX: RHHBY) and Flatiron Health, Inc. announced that the two partners have signed a definitive agreement under which Roche will acquire all shares of Flatiron Health, following on from an existing equity stake of 12.6%. The transaction is expected to close in the first half of 2018. (Source: World Pharma News)
Source: World Pharma News - February 21, 2018 Category: Pharmaceuticals Tags: Featured Roche Business and Industry Source Type: news

ERLEADA (apalutamide), the first FDA-approved treatment for non-metastatic, castration-resistant prostate cancer, available for order at Biologics, Inc.
CARY, N.C. (February 21, 2018) —Biologics, Inc., a McKesson Specialty Health oncology and complex care pharmacy services company, has been selected by the Janssen Pharmaceutical Companies of Johnson& Johnson1  to be in the limited distribution network for ERLEADA™ (apalutamide), the first FDA-approv... (Source: McKesson News)
Source: McKesson News - February 21, 2018 Category: Information Technology Source Type: news

Facial Cancer Decimating Tasmanian Devil Population
Title: Facial Cancer Decimating Tasmanian Devil PopulationCategory: Health NewsCreated: 2/20/2018 12:00:00 AMLast Editorial Review: 2/21/2018 12:00:00 AM (Source: MedicineNet Cancer General)
Source: MedicineNet Cancer General - February 21, 2018 Category: Cancer & Oncology Source Type: news

Newer Breast MRI May Be More Accurate and Easier
Title: Newer Breast MRI May Be More Accurate and EasierCategory: Health NewsCreated: 2/20/2018 12:00:00 AMLast Editorial Review: 2/21/2018 12:00:00 AM (Source: MedicineNet Cancer General)
Source: MedicineNet Cancer General - February 21, 2018 Category: Cancer & Oncology Source Type: news

Mirada introduces AI software for radiation oncology
Imaging software developer Mirada Medical has introduced DLCExpert, a software...Read more on AuntMinnie.comRelated Reading: Optellum, Mirada present lung cancer study at RSNA 2017 Mirada's deep-learning contours match human-drawn contours Mirada showcases XD:PACS at RSNA 2016 Philips, Mirada sign distribution deal Mirada launches nuclear medicine software at RSNA 2015 (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - February 21, 2018 Category: Radiology Source Type: news

Densitas highlights study in Breast Cancer Research
Medical software developer Densitas is directing attention to a recent review...Read more on AuntMinnie.comRelated Reading: Densitas deploys breast density software throughout Canada Densitas touts breast density clinical research Densitas accepted into JLABS @ Toronto Densitas highlights breast density research at ECR Densitas receives CE Mark, Canadian clearance (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - February 21, 2018 Category: Radiology Source Type: news

MD Anderson receives $22 million in CPRIT funding for research, prevention and recruitment
(University of Texas M. D. Anderson Cancer Center) The University of Texas MD Anderson Cancer Center was awarded $22.3 million from the Cancer Prevention and Research Institute of Texas (CPRIT), accounting for 30 percent of the $73.5 million in awards CPRIT announced today. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - February 21, 2018 Category: Cancer & Oncology Source Type: news

Precision cancer therapy effective in both children and adults
(Children's Hospital Los Angeles) Three quarters of patients, both adults and children, with a variety of advanced cancers occurring in different sites of the body responded to larotrectinib, a novel therapy that targets a specific genetic mutation. Results of a phase 1/2 trial have been published in the New England Journal of Medicine. Unlike most cancer therapies, this oral treatment is based on the genetic traits of the tumor and not the organ where the cancer originated. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - February 21, 2018 Category: Cancer & Oncology Source Type: news

Kinase inhibitor larotrectinib shows durable anti-tumor abilities in patients of all ages with 17 un
(University of Texas M. D. Anderson Cancer Center) Three simultaneous safety and efficacy studies of the drug larotrectinib reported an overall response rate of 75 percent for patients ages four months to 76 years with 17 different cancer diagnoses. All patients had tumors with tropomyosin receptor kinase (TRK) fusions, gene mutations that switch on TRK genes, allowing cancer growth. The studies indicate larotrectinib as a potentially powerful new treatment approach for the approximately 5,000 patients with these forms of cancer. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - February 21, 2018 Category: Cancer & Oncology Source Type: news

Drug successfully targets cancers with tumor-specific gene mutations
(Nemours) Pediatric and adult cancers with one of three fusion genes responds well to a new drug, larotrectinib, according to a study published today in the New England Journal of Medicine. The drug is designed to target a specific tumor gene mutation known as tropomyosin receptor kinases (TRK) that can occur in various tumor types. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - February 21, 2018 Category: Cancer & Oncology Source Type: news

Scientists discover new nanoparticle, dubbed exomeres
(Weill Cornell Medicine) A new cellular messenger discovered by Weill Cornell Medicine scientists may help reveal how cancer cells co-opt the body's intercellular delivery service to spread to new locations in the body. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - February 21, 2018 Category: Cancer & Oncology Source Type: news

First 3-D digital models reveal the development of the extinct Tasmanian tiger
(University of Melbourne) Researchers from Museums Victoria and the University of Melbourne have CT scanned all 13 known Tasmanian tiger joey specimens to create 3-D digital models which have allowed them to study their skeletons and internal organs, and reconstruct their growth and development. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - February 21, 2018 Category: Cancer & Oncology Source Type: news

Five novel genetic changes linked to pancreatic cancer risk
(Johns Hopkins Medicine) In what is believed to be the largest pancreatic cancer genome-wide association study to date, researchers at the Johns Hopkins Kimmel Cancer Center and the National Cancer Institute, and collaborators from over 80 other institutions worldwide discovered changes to five new regions in the human genome that may increase the risk of pancreatic cancer. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - February 21, 2018 Category: Cancer & Oncology Source Type: news

Breakthrough for peptide medication
(Technical University of Munich (TUM)) Peptides, short amino acid chains that control many functions in the human body, represent a billion-dollar market, also in the pharmaceutical industry. But, normally these medications must be injected. A research team led by the Technical University of Munich (TUM) has now determined how peptides can be designed so that they can be easily administered as a liquid or tablet. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - February 21, 2018 Category: Cancer & Oncology Source Type: news