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Compass Course: Efficacy Study
Condition:   Breast Cancer Intervention:   Behavioral: Compass Course Sponsor:   Allina Health System Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 22, 2018 Category: Research Source Type: clinical trials

PhII Trial Panitumumab, Nivolumab, Ipilimumab in Kras/Nras/BRAF Wild-type MSS Refractory mCRC
Condition:   Colon Cancer Interventions:   Drug: Panitumumab;   Drug: Nivolumab;   Drug: Ipilimumab Sponsors:   UNC Lineberger Comprehensive Cancer Center;   Amgen;   Bristol-Myers Squibb Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 22, 2018 Category: Research Source Type: clinical trials

Docetaxel, Carboplatin, and Rucaparib Camsylate in Treating Patients With Metastatic Castration Resistant Prostate Cancer With Homologous Recombination DNA Repair Deficiency
Conditions:   ATM Gene Mutation;   BRCA1 Gene Mutation;   BRCA2 Gene Mutation;   Castration Levels of Testosterone;   Castration-Resistant Prostate Carcinoma;   Homologous Recombination Deficiency;   Prostate Carcinoma Metastatic in the Bone;   PSA Level Greater Than or Equal to  Two;   PSA Progression;   Stage IV Prostate Adenocarcinoma AJCC v7 Interventions:   Drug: Carboplatin;   Drug: Docetaxel; &n...
Source: ClinicalTrials.gov - February 22, 2018 Category: Research Source Type: clinical trials

Preoperative Localization of Sentinel Lymph Node in Breast Cancer Patients By Novel Computed Tomography-Lymphography Guided Technique
Condition:   Breast Cancer Intervention:   Device: preoperative localization of SLN detected by CTLG by either methods Sponsor:   Mansoura University Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 22, 2018 Category: Research Source Type: clinical trials

Prediction of Response to 2nd-line Hormone Therapy by FES CT/PET in Patients With Metastatic Breast Cancer
Condition:   Metastatic Breast Cancer Intervention:   Diagnostic Test: FES PET/CT Sponsor:   Institut Cancerologie de l'Ouest Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 22, 2018 Category: Research Source Type: clinical trials

Comparison of Digital Breast Tomosynthesis to Conventional Mammography
Condition:   Breast Cancer Intervention:   Other: 2D/3D Tomosynthesis Sponsor:   University Health Network, Toronto Active, not recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 22, 2018 Category: Research Source Type: clinical trials

Facilitating Oncology Patient-Clinician Communication Via E-health Innovations
Condition:   Breast Cancer Intervention:   Behavioral: CaringGuidance™ After Breast Cancer Diagnosis Sponsor:   University of Nebraska Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 22, 2018 Category: Research Source Type: clinical trials

ECT-001 (UM171) Expanded Cord Blood Transplant to Treat High-risk Multiple Myeloma
Condition:   Multiple Myeloma Intervention:   Biological: ECT-001 (UM171) expanded cord blood Sponsors:   Ciusss de L'Est de l'Île de Montréal;   ExcellThera;   Centre de Commercialisation en Immunothérapie du Cancer (C3i) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 22, 2018 Category: Research Source Type: clinical trials

Compass Course: Efficacy Study
Condition:   Breast Cancer Intervention:   Behavioral: Compass Course Sponsor:   Allina Health System Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 22, 2018 Category: Research Source Type: clinical trials

PhII Trial Panitumumab, Nivolumab, Ipilimumab in Kras/Nras/BRAF Wild-type MSS Refractory mCRC
Condition:   Colon Cancer Interventions:   Drug: Panitumumab;   Drug: Nivolumab;   Drug: Ipilimumab Sponsors:   UNC Lineberger Comprehensive Cancer Center;   Amgen;   Bristol-Myers Squibb Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 22, 2018 Category: Research Source Type: clinical trials

Docetaxel, Carboplatin, and Rucaparib Camsylate in Treating Patients With Metastatic Castration Resistant Prostate Cancer With Homologous Recombination DNA Repair Deficiency
Conditions:   ATM Gene Mutation;   BRCA1 Gene Mutation;   BRCA2 Gene Mutation;   Castration Levels of Testosterone;   Castration-Resistant Prostate Carcinoma;   Homologous Recombination Deficiency;   Prostate Carcinoma Metastatic in the Bone;   PSA Level Greater Than or Equal to  Two;   PSA Progression;   Stage IV Prostate Adenocarcinoma AJCC v7 Interventions:   Drug: Carboplatin;   Drug: Docetaxel; &n...
Source: ClinicalTrials.gov - February 22, 2018 Category: Research Source Type: clinical trials

Preoperative Localization of Sentinel Lymph Node in Breast Cancer Patients By Novel Computed Tomography-Lymphography Guided Technique
Condition:   Breast Cancer Intervention:   Device: preoperative localization of SLN detected by CTLG by either methods Sponsor:   Mansoura University Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 22, 2018 Category: Research Source Type: clinical trials

Prediction of Response to 2nd-line Hormone Therapy by FES CT/PET in Patients With Metastatic Breast Cancer
Condition:   Metastatic Breast Cancer Intervention:   Diagnostic Test: FES PET/CT Sponsor:   Institut Cancerologie de l'Ouest Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 22, 2018 Category: Research Source Type: clinical trials

Comparison of Digital Breast Tomosynthesis to Conventional Mammography
Condition:   Breast Cancer Intervention:   Other: 2D/3D Tomosynthesis Sponsor:   University Health Network, Toronto Active, not recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 22, 2018 Category: Research Source Type: clinical trials

Facilitating Oncology Patient-Clinician Communication Via E-health Innovations
Condition:   Breast Cancer Intervention:   Behavioral: CaringGuidance™ After Breast Cancer Diagnosis Sponsor:   University of Nebraska Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 22, 2018 Category: Research Source Type: clinical trials

ECT-001 (UM171) Expanded Cord Blood Transplant to Treat High-risk Multiple Myeloma
Condition:   Multiple Myeloma Intervention:   Biological: ECT-001 (UM171) expanded cord blood Sponsors:   Ciusss de L'Est de l'Île de Montréal;   ExcellThera;   Centre de Commercialisation en Immunothérapie du Cancer (C3i) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 22, 2018 Category: Research Source Type: clinical trials

Feasibility of the LUM Imaging System for Detection of Prostate Cancer
Conditions:   Prostate Cancer;   Neoplasm, Residual Intervention:   Combination Product: LUM Imaging System Sponsor:   Lumicell, Inc. Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 21, 2018 Category: Research Source Type: clinical trials

TCR-engineered T Cells in NSCLC and HCC Patients
Conditions:   Solid Tumor, Adult;   Cancer;   Hepatocellular Carcinoma;   Hepatocellular Cancer;   Nonsmall Cell Lung Cancer;   Squamous Cell Lung Cancer;   Squamous Cell Cancer;   Liver Cancer;   Lung Cancer Interventions:   Drug: IMA202 Product;   Device: IMA_Detect Sponsors:   Immatics US, Inc.;   M.D. Anderson Cancer Center Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 21, 2018 Category: Research Source Type: clinical trials

Osteopathy Treatment for Cancer Pain Related to the Confinement to Bed
Condition:   Cancer Patient Confined in the Bed Intervention:   Other: Osteopathic treatment Sponsor:   Hospices Civils de Lyon Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 21, 2018 Category: Research Source Type: clinical trials

Androgen Deprivation Therapy Muscle Protein Metabolism and Blood Glucose
Conditions:   Prostate Cancer;   Resistance Exercise;   Androgen Deprivation Therapy Intervention:   Drug: Zoladex Sponsors:   Norwegian School of Sport Sciences;   University Hospital, Akershus;   Oslo University Hospital;   Rigshospitalet, Denmark;   University of Copenhagen;   King's College London Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 21, 2018 Category: Research Source Type: clinical trials

Non-contrast MR Imaging for Whole Body Cancer Detection and Characterization
Condition:   Prostate Cancer Intervention:   Diagnostic Test: Whole Body Non-Contrast MRI Sponsors:   University of California, San Diego;   Prostate Cancer Foundation;   United States Department of Defense Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 21, 2018 Category: Research Source Type: clinical trials

FS118 First in Human Study in Patients With Advanced Malignancies After PD-1/PD-L1 Containing Therapy
Conditions:   Advanced Cancer;   Metastatic Cancer Intervention:   Drug: FS118 Sponsor:   F-star Delta Limited Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 21, 2018 Category: Research Source Type: clinical trials

Robotic Nipple-Sparing Mastectomy Vs Conventional Open Technique
Condition:   Breast Cancer Interventions:   Procedure: Robotic NSM;   Procedure: Open NSM Sponsor:   European Institute of Oncology Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 21, 2018 Category: Research Source Type: clinical trials

Feasibility of the LUM Imaging System for Detection of Prostate Cancer
Conditions:   Prostate Cancer;   Neoplasm, Residual Intervention:   Combination Product: LUM Imaging System Sponsor:   Lumicell, Inc. Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 21, 2018 Category: Research Source Type: clinical trials

TCR-engineered T Cells in NSCLC and HCC Patients
Conditions:   Solid Tumor, Adult;   Cancer;   Hepatocellular Carcinoma;   Hepatocellular Cancer;   Nonsmall Cell Lung Cancer;   Squamous Cell Lung Cancer;   Squamous Cell Cancer;   Liver Cancer;   Lung Cancer Interventions:   Drug: IMA202 Product;   Device: IMA_Detect Sponsors:   Immatics US, Inc.;   M.D. Anderson Cancer Center Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 21, 2018 Category: Research Source Type: clinical trials

Osteopathy Treatment for Cancer Pain Related to the Confinement to Bed
Condition:   Cancer Patient Confined in the Bed Intervention:   Other: Osteopathic treatment Sponsor:   Hospices Civils de Lyon Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 21, 2018 Category: Research Source Type: clinical trials

Androgen Deprivation Therapy Muscle Protein Metabolism and Blood Glucose
Conditions:   Prostate Cancer;   Resistance Exercise;   Androgen Deprivation Therapy Intervention:   Drug: Zoladex Sponsors:   Norwegian School of Sport Sciences;   University Hospital, Akershus;   Oslo University Hospital;   Rigshospitalet, Denmark;   University of Copenhagen;   King's College London Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 21, 2018 Category: Research Source Type: clinical trials

Non-contrast MR Imaging for Whole Body Cancer Detection and Characterization
Condition:   Prostate Cancer Intervention:   Diagnostic Test: Whole Body Non-Contrast MRI Sponsors:   University of California, San Diego;   Prostate Cancer Foundation;   United States Department of Defense Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 21, 2018 Category: Research Source Type: clinical trials

FS118 First in Human Study in Patients With Advanced Malignancies After PD-1/PD-L1 Containing Therapy
Conditions:   Advanced Cancer;   Metastatic Cancer Intervention:   Drug: FS118 Sponsor:   F-star Delta Limited Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 21, 2018 Category: Research Source Type: clinical trials

Robotic Nipple-Sparing Mastectomy Vs Conventional Open Technique
Condition:   Breast Cancer Interventions:   Procedure: Robotic NSM;   Procedure: Open NSM Sponsor:   European Institute of Oncology Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 21, 2018 Category: Research Source Type: clinical trials

Loxo Oncology Announces Publication of Larotrectinib Clinical Data in The New England Journal of Medicine
STAMFORD, Conn., Feb. 21, 2018 (GLOBE NEWSWIRE) -- Loxo Oncology, Inc. (Nasdaq:LOXO), a biopharmaceutical company innovating the development of highly selective medicines for patients with genetically defined cancers, and Bayer AG, Germany, today... (Source: Drugs.com - Clinical Trials)
Source: Drugs.com - Clinical Trials - February 21, 2018 Category: Pharmaceuticals Source Type: clinical trials

Male synthetic sling versus artificial urinary sphincter trial for men with urodynamic stress incontinence after prostate surgery (MASTER): study protocol for a randomised controlled trial
DiscussionA robust examination of the comparative effectiveness of the male synthetic sling will provide high-quality evidence to determine whether or not it should be adopted widely in the NHS.Trial registrationInternational Standard Randomised Controlled Trial Registry: NumberISRCTN49212975. Registered on 22 July 2013. First patient randomised on 29 January 2014. (Source: Trials)
Source: Trials - February 21, 2018 Category: Research Source Type: clinical trials

Oncological Outcome of Contralateral Submental Artery Island Flap Versus Primary Closure in Tongue Squamous Cell Carcinoma
Condition:   Tongue Squamous Cell Carcinoma Interventions:   Procedure: contralateral submental flap for tongue cancer defect;   Procedure: primary closure for tongue cancer defect Sponsor:   Cairo University Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 20, 2018 Category: Research Source Type: clinical trials

Individualized Pharmaceutical-care in Outpatients With Cancer Pain
Condition:   Cancer Pain Intervention:   Other: Pharmaceutical care Sponsor:   Zhejiang Cancer Hospital Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 20, 2018 Category: Research Source Type: clinical trials

Sorafenib and Nivolumab as First-Line Therapy in Treating Participants With Unresectable, Locally Advanced or Metastatic Liver Cancer
Conditions:   Stage III Hepatocellular Carcinoma AJCC v8;   Stage IIIA Hepatocellular Carcinoma AJCC v8;   Stage IIIB Hepatocellular Carcinoma AJCC v7;   Stage IIIC Hepatocellular Carcinoma AJCC v7;   Stage IV Hepatocellular Carcinoma AJCC v8;   Stage IVA Hepatocellular Carcin oma AJCC v8;   Stage IVB Hepatocellular Carcinoma AJCC v8 Interventions:   Other: Laboratory Biomarker Analysis;   Bi...
Source: ClinicalTrials.gov - February 20, 2018 Category: Research Source Type: clinical trials

Determinants of Resistance to First-line Therapy With an AI and Palbociclib for HR+ MBC
Condition:   Breast Cancer Intervention:   Drug: Aromatase Inhibitor and Palbociclib Sponsor:   Sidney Kimmel Comprehensive Cancer Center Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 20, 2018 Category: Research Source Type: clinical trials

Needlescopic-assisted Uniportal vs Uniportal VATS
Conditions:   Lung Cancer;   Lung Cancer Metastatic;   Bullous Disease Lung;   Nodule Solitary Pulmonary;   Mediastinal Tumor Intervention:   Procedure: Thoracoscopic surgery Sponsor:   National Taiwan University Hospital Hsin-Chu Branch Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 20, 2018 Category: Research Source Type: clinical trials

ABI-009 (Nab-rapamycin) in Combination With FOLFOX and Bevacizumab as First-line Therapy in Patients With Advanced or Metastatic Colorectal Cancer
Condition:   Colorectal Cancer Metastatic Intervention:   Drug: ABI-009; nab-rapamycin; albumin-bound rapamycin Sponsor:   Aadi, LLC Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 20, 2018 Category: Research Source Type: clinical trials

PF-06463922 for Crizotinib Pretreated ROS1 Positive Non-small-cell Lung Cancer
Condition:   Carcinoma, Non-Small-Cell Lung Intervention:   Drug: PF-06463922 (Lorlatinb) Sponsors:   Fondazione Ricerca Traslazionale;   Clinical Research Technology S.r.l. Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 20, 2018 Category: Research Source Type: clinical trials

Vaccine + Durvalumab in Human Papilloma Virus (HPV) Cancers
Conditions:   Malignant Neoplasms of Digestive Organs;   Malignant Neoplasms of Female Genital Organs;   Malignant Neoplasms of Male Genital Organs;   Human Papilloma Virus Interventions:   Biological: MEDI0457;   Drug: Durvalumab;   Procedure: Electroporation Sponsors:   M.D. Anderson Cancer Center;   AstraZeneca;   Inovio Pharmaceuticals Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 20, 2018 Category: Research Source Type: clinical trials

Study of the Molecular Features of Postmenopausal Women With HR+ HER2-negative aBC on First-line Treatment With Ribociclib and Letrozole
Condition:   Breast Cancer Interventions:   Drug: Ribociclib;   Drug: Letrozole Sponsor:   Novartis Pharmaceuticals Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 20, 2018 Category: Research Source Type: clinical trials

Comparison Study of PET/CT or PET/MRI Imaging to Magnetic Resonance Imaging (MRI) Alone in Men With Prostate Cancer
Condition:   Prostate Cancer Interventions:   Drug: PET/MRI with Gallium-68 labeled PSMA-HBED-CC;   Drug: Multiple PET/MRI with Gallium-68 labeled PSMA-HBED-CC;   Drug: PET/CT with Gallium-68 labeled PSMA-HBED-CC Sponsor:   Weill Medical College of Cornell University Enrolling by invitation (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 20, 2018 Category: Research Source Type: clinical trials

Oncological Outcome of Contralateral Submental Artery Island Flap Versus Primary Closure in Tongue Squamous Cell Carcinoma
Condition:   Tongue Squamous Cell Carcinoma Interventions:   Procedure: contralateral submental flap for tongue cancer defect;   Procedure: primary closure for tongue cancer defect Sponsor:   Cairo University Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 20, 2018 Category: Research Source Type: clinical trials

Individualized Pharmaceutical-care in Outpatients With Cancer Pain
Condition:   Cancer Pain Intervention:   Other: Pharmaceutical care Sponsor:   Zhejiang Cancer Hospital Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 20, 2018 Category: Research Source Type: clinical trials

Sorafenib and Nivolumab as First-Line Therapy in Treating Participants With Unresectable, Locally Advanced or Metastatic Liver Cancer
Conditions:   Stage III Hepatocellular Carcinoma AJCC v8;   Stage IIIA Hepatocellular Carcinoma AJCC v8;   Stage IIIB Hepatocellular Carcinoma AJCC v7;   Stage IIIC Hepatocellular Carcinoma AJCC v7;   Stage IV Hepatocellular Carcinoma AJCC v8;   Stage IVA Hepatocellular Carcin oma AJCC v8;   Stage IVB Hepatocellular Carcinoma AJCC v8 Interventions:   Other: Laboratory Biomarker Analysis;   Bi...
Source: ClinicalTrials.gov - February 20, 2018 Category: Research Source Type: clinical trials

Determinants of Resistance to First-line Therapy With an AI and Palbociclib for HR+ MBC
Condition:   Breast Cancer Intervention:   Drug: Aromatase Inhibitor and Palbociclib Sponsor:   Sidney Kimmel Comprehensive Cancer Center Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 20, 2018 Category: Research Source Type: clinical trials

Needlescopic-assisted Uniportal vs Uniportal VATS
Conditions:   Lung Cancer;   Lung Cancer Metastatic;   Bullous Disease Lung;   Nodule Solitary Pulmonary;   Mediastinal Tumor Intervention:   Procedure: Thoracoscopic surgery Sponsor:   National Taiwan University Hospital Hsin-Chu Branch Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 20, 2018 Category: Research Source Type: clinical trials

ABI-009 (Nab-rapamycin) in Combination With FOLFOX and Bevacizumab as First-line Therapy in Patients With Advanced or Metastatic Colorectal Cancer
Condition:   Colorectal Cancer Metastatic Intervention:   Drug: ABI-009; nab-rapamycin; albumin-bound rapamycin Sponsor:   Aadi, LLC Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 20, 2018 Category: Research Source Type: clinical trials

PF-06463922 for Crizotinib Pretreated ROS1 Positive Non-small-cell Lung Cancer
Condition:   Carcinoma, Non-Small-Cell Lung Intervention:   Drug: PF-06463922 (Lorlatinb) Sponsors:   Fondazione Ricerca Traslazionale;   Clinical Research Technology S.r.l. Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 20, 2018 Category: Research Source Type: clinical trials

Vaccine + Durvalumab in Human Papilloma Virus (HPV) Cancers
Conditions:   Malignant Neoplasms of Digestive Organs;   Malignant Neoplasms of Female Genital Organs;   Malignant Neoplasms of Male Genital Organs;   Human Papilloma Virus Interventions:   Biological: MEDI0457;   Drug: Durvalumab;   Procedure: Electroporation Sponsors:   M.D. Anderson Cancer Center;   AstraZeneca;   Inovio Pharmaceuticals Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 20, 2018 Category: Research Source Type: clinical trials