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NIAID-Sponsored Trial of a Universal Influenza Vaccine Begins
Phase 2 clinical trial of investigational universal influenza vaccines has begun in the U.S. (Source: National Institutes of Health (NIH) News Releases)
Source: National Institutes of Health (NIH) News Releases - May 4, 2018 Category: American Health Source Type: news

NIAID-sponsored trial of a universal influenza vaccine begins
(NIH/National Institute of Allergy and Infectious Diseases) A Phase 2 clinical trial of an investigational universal influenza vaccine intended to protect against multiple strains of the virus has begun. The study is sponsored by the National Institute of Allergy and Infectious Diseases and is being conducted at US sites that are part of the NIAID-funded Vaccine and Treatment Evaluation Units. The trial is testing an experimental vaccine called M-001 for safety and its ability to produce potentially broad protective immune responses. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - May 4, 2018 Category: Infectious Diseases Source Type: news

Flu Vaccines Have High Impact, Even With Relatively Low Efficacy
MONDAY, April 30, 2018 -- Even relatively low-efficacy influenza vaccines can have a high impact, especially with optimal distribution across age groups, according to a study published online April 30 in the Proceedings of the National Academy of... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - April 30, 2018 Category: Pharmaceuticals Source Type: news

Horses Get the Flu, Too
Flu vaccines for horses haven ’t been updated in more than 25 years, but Rochester researchers have developed a new live equine influenza vaccine that is safe and more protective than existing vaccines. A new vaccine is needed not only to keep horses healthy, but also to protect people. (Source: University of Rochester Medical Center Press Releases)
Source: University of Rochester Medical Center Press Releases - April 30, 2018 Category: Universities & Medical Training Authors: University of Rochester Medical Center Source Type: news

Horses get the flu, too
(University of Rochester Medical Center) Flu vaccines for horses haven't been updated in more than 25 years, but researchers have developed a new live equine influenza vaccine that's safe and more protective than existing vaccines. Proactively preventing the spread of flu in animals is important, as animals are the most likely source of future human pandemics. Animals can be infected with multiple influenza viruses and have the potential to act as 'mixing vessels,' generating new strains that could infect people. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - April 30, 2018 Category: International Medicine & Public Health Source Type: news

QuickStats: Percentage of Currently Employed Adults Aged ≥18 Years Who Received Influenza Vaccine in the Past 12 Months, by Employment Category — National Health Interview Survey, United States, 2012 and 2016
(Source: CDC Morbidity and Mortality Weekly Report)
Source: CDC Morbidity and Mortality Weekly Report - April 26, 2018 Category: American Health Source Type: news

VaxArray immunogenicity study published in Vaccine
(InDevR, Inc.) 'VaxArray for Hemagglutinin and Neuraminidase Potency Testing of Influenza Vaccines' describes a study designed to test the relationship between VaxArray-measured potency and vaccine-induced immunogenicity in mice. The study results represent a milestone in an industry-wide effort to qualify new potency assays for influenza vaccines. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - April 26, 2018 Category: Infectious Diseases Source Type: news

Infection prevention specialist nurse named ‘flu fighter champion’
An infection prevention specialist nurse from Yorkshire has been given a national award for her work to encourage influenza vaccination among her trust ’s staff ahead of last winter. (Source: Nursing Times)
Source: Nursing Times - April 25, 2018 Category: Nursing Source Type: news

What Causes Hyponatremia?
Discussion Normal kidneys regulate water balance to maintain a plasma osmolality of 275-290 mOsm/kg normally. Thirst and arginine vasopressin or antidiuretic hormone (ADH) are the primary regulators of plasma osmolality. ADH is made in the hypothalamus and released by the posterior pituitary gland. ADH acts on the kidney’s distal collecting duct to increase water reabsorption. ADH is appropriately released in hypovolemic states, such as dehydration caused by gastroenteritis. ADH has an ~10 minute half-life and therefore can respond to rapid changes in volume status. Sodium balance is regulated by aldosterone (as part...
Source: PediatricEducation.org - April 23, 2018 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

World Immunization Week 2018: Protected Together, #VaccinesWork
22 April 2018, Cairo – This year’s World Immunization Week campaign, celebrated from 24 to 30 April, aims to highlight that protecting entire communities with vaccines protects everyone and so the theme of this year’s campaign is “Protected Together, #VaccinesWork”.  Immunization is one of the most successful and cost-effective health interventions. Studies show that every US$ 1 spent on childhood immunization returns US$ 44 in economic and social benefits.  Immunization protects everyone – from infants to senior citizens – against disabling illnesses, disability a...
Source: WHO EMRO News - April 22, 2018 Category: Middle East Health Source Type: news

Fall 2018 flu vaccine will be 20 percent effective, study predicts
This fall's flu vaccine will be 20 percent effective for the dominant circulating strain of influenza A, the same as shots given the past two years. (Source: Health News - UPI.com)
Source: Health News - UPI.com - April 19, 2018 Category: Consumer Health News Source Type: news

Kenya:Kenya Doesn't Have a Flu Vaccine Policy. Why It Needs One for Babies
[The Conversation Africa] Each year the World Health Organisation gathers data on influenza strains and recommends which strains countries should include in formulating vaccines for the next year. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - April 19, 2018 Category: African Health Source Type: news

Study predicts 2018 flu vaccine will have 20 percent efficacy
(Rice University) A Rice University study of 6,610 human flu sequences predicts that this fall's flu vaccine will likely have the same reduced efficacy against the dominant circulating strain of influenza A as the vaccine given in 2016 and 2017 due to viral mutations related to vaccine production in eggs. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - April 19, 2018 Category: International Medicine & Public Health Source Type: news

VaxArray rapid response to seasonal strain changes for influenza vaccines
(InDevR, Inc.) InDevR expanded its license agreement with the Technology Transfer Program at the US Food and Drug Administration (FDA) to address strain changes recommended by the World Health Organization (WHO) for 2018/2019 seasonal influenza vaccines. The new VaxArray ® Influenza Seasonal HA reagent kit (v2.0) has improved sensitivity to the latest A/H3N2 and B/Victoria-like viruses. Version 2.0 of the potency test is available now for evaluation and will be available for purchase by April 21, 2018. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - April 10, 2018 Category: Biology Source Type: news

Research offers clues for improved influenza vaccine design
These efforts contribute to NIAID ’s larger plan to develop a universal influenza vaccine. (Source: National Institutes of Health (NIH) News Releases)
Source: National Institutes of Health (NIH) News Releases - April 6, 2018 Category: American Health Source Type: news

Impact of Initial Influenza Exposure on Immunity in Infants (U01 Clinical Trial Not Allowed)
Funding to establish, follow, and characterize longitudinal cohorts of infants to determine how initial and repeated natural influenza infections and/or influenza vaccinations shape infant and childhood immunity to future influenza exposures. The ultimate goal of this research is to provide key information to facilitate design of durable, broadly protective influenza vaccines. (Source: PHPartners.org)
Source: PHPartners.org - April 6, 2018 Category: International Medicine & Public Health Source Type: news

A third of health practitioners do not get vaccinated against flu
This NIHR Signal found flu vaccination uptake amongst healthcare workers (HCWs) in England is below NHS target of 75%. This suggests that efforts to improve immunisation uptake must start with education about the benefits of influenza immunisation for HCWs themselves (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - April 6, 2018 Category: Consumer Health News Source Type: news

Research offers clues for improved influenza vaccine design
(NIH/National Institute of Allergy and Infectious Diseases) Influenza vaccines that better target the influenza surface protein called neuraminidase (NA) could offer broad protection against various influenza virus strains and lessen the severity of illness, according to new research published in Cell. The new research builds on previous studies of NA and was conducted by a team of scientists including investigators from the Centers of Excellence for Influenza Research and Surveillance (CEIRS) program, which is organized and funded by NIAID. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - April 6, 2018 Category: Infectious Diseases Source Type: news

For a better influenza vaccine, focus on the neglected 'N'
(University of Chicago Medical Center) In the April 5, 2018, issue of the journal Cell, researchers push for greater emphasis on the neglected viral-surface influenza protein neuraminidase. For decades, flu vaccines have concentrated on hemagglutinin. The authors maintain that a focus on neuraminidase could lower infection rates and lessen severity. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - April 5, 2018 Category: Infectious Diseases Source Type: news

In promoting vaccination, behavioral strategies more effective than persuasion
(Association for Psychological Science) Faced with outbreaks of influenza and other vaccine-preventable diseases, parents, educators, healthcare providers, and policymakers around the world often want to know how to persuade people to get their vaccinations. But a comprehensive review of the scientific findings from research on vaccination behavior shows that the most effective interventions focus directly on shaping patients' and parents' behavior instead of trying to change their minds. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - April 4, 2018 Category: International Medicine & Public Health Source Type: news

Recombinant Influenza Vaccine Found to Be Safe in Children
MONDAY, April 2, 2018 -- The recombinant influenza vaccine (RIV4) is well tolerated in children aged 6 to 17 years, and it provides immunogenicity comparable to that of the inactivated vaccine, according to a study published online April 2 in... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - April 2, 2018 Category: Pharmaceuticals Source Type: news

A Second Wave of Flu May Be On the Way, CDC Warns
Flu season may have peaked in February, but we’re not out of the woods yet. The bulk of this year’s deadly flu season was dominated by the H3N2 virus, an influenza A strain that is more severe and less receptive to vaccines than other types of the disease. As the season winds down, however, influenza B has overtaken influenza A, setting the scene for a possible second wave of flu, according to Centers for Disease Control and Prevention (CDC) data. While flu activity nationwide has dropped to just above non-flu-season levels, influenza B viruses were reported more frequently than influenza A viruses during the w...
Source: TIME: Health - March 27, 2018 Category: Consumer Health News Authors: Jamie Ducharme Tags: Uncategorized healthytime onetime public health Source Type: news

University of Maryland School of Medicine experts lead trial on avian flu vaccine
(University of Maryland School of Medicine) Vaccine experts at the University of Maryland School of Medicine have begun multiple clinical trials of vaccines designed to protect against H7N9, an avian influenza virus that was first reported in humans in 2013 in China. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 22, 2018 Category: International Medicine & Public Health Source Type: news

New flu forecasting system being rolled out; will aggressively push toxic vaccines with "science" propaganda
(Natural News) Researchers from the Columbia University Mailman School of Public Health in New York City have come up with a new tracking system that they claim will be able to predict the geographic spread of seasonal influenza before it starts to run its course. Published in the journal PNAS, a paper outlining the new... (Source: NaturalNews.com)
Source: NaturalNews.com - March 21, 2018 Category: Consumer Health News Source Type: news

UAB approved to test avian flu vaccines
UAB ’s School of Medicine’s Alabama Vaccine Research Clinic has been selected as a national trial site to test a new avian flu vaccine. The clinic is one of four national trial sites to test a candidate for the H7N9, a strain of the avian influenza.  The trial is sponsored by the National Instit ute of Allergy and Infectious Disease, part of the National Institutes of Health, with the purpose of having an effective vaccine ready for any future H7N9 pandemic. “We are excited for the opportunity… (Source: bizjournals.com Health Care News Headlines)
Source: bizjournals.com Health Care News Headlines - March 19, 2018 Category: Health Management Authors: Tyler Patchen Source Type: news

NIH approves clinical trials for vaccine against avian influenza
A federal agency has approved two clinical Phase 2 trials to vaccinate for H7N9, a strain of avian influenza that has not reached humans in the United States. (Source: Health News - UPI.com)
Source: Health News - UPI.com - March 16, 2018 Category: Consumer Health News Source Type: news

H7N9 Influenza Vaccine Clinical Trials Begin
Two new clinical trials testing an experimental vaccine to prevent influenza caused by an H7N9 influenza virus are now enrolling volunteers at sites across the United States. (Source: PHPartners.org)
Source: PHPartners.org - March 15, 2018 Category: International Medicine & Public Health Source Type: news

H7N9 influenza vaccine clinical trials begin
Trials for an experimental vaccine for the H7N9 influenza virus are now enrolling volunteers at sites across the United States. (Source: National Institutes of Health (NIH) News Releases)
Source: National Institutes of Health (NIH) News Releases - March 15, 2018 Category: American Health Source Type: news

Alexa Barbin dies of the flu hours after she felt 'a bit of a cold'  
Alexa Barbin, 19, of Escondido, California, died from influenza B virus just one day after experiencing cold-like symptoms. The teen did not receive a flu vaccination this season. (Source: the Mail online | Health)
Source: the Mail online | Health - March 15, 2018 Category: Consumer Health News Source Type: news

H7N9 influenza vaccine clinical trials begin
(NIH/National Institute of Allergy and Infectious Diseases) Two new clinical trials testing an experimental vaccine to prevent influenza caused by an H7N9 influenza virus are now enrolling volunteers at sites across the U.S. The Phase 2 studies, sponsored by NIAID, will test different dosages of the inactivated influenza vaccine candidate (called 2017 H7N9 IIV) as well as different vaccination schedules. The studies also will evaluate whether an adjuvant boosts the immune responses of people receiving the vaccine. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - March 15, 2018 Category: Infectious Diseases Source Type: news

Examining U.S. Public Health Preparedness for and Response Efforts to Seasonal Influenza
U.S. House of Representatives, Committee on Energy and Commerce. 03/08/2018 This two-hour, 34-minute Congressional hearing examines the U.S. Department of Health and Human Services'efforts to combat seasonal influenza, develop an effective influenza vaccine, and prepare a long-term strategy to improve seasonal influenza preparedness. It discusses how one long-term goal to improve preparedness for and response to the influenza is to develop a universal vaccine that would provide long-lasting immunity against multiple strains of the influenza. (Video or Multimedia) (Source: Disaster Lit: Resource Guide for Disaster Medicine and Public Health)
Source: Disaster Lit: Resource Guide for Disaster Medicine and Public Health - March 10, 2018 Category: International Medicine & Public Health Authors: The U.S. National Library of Medicine Source Type: news

Flu Shot Cuts Risk for Death by Half in Heart Failure Flu Shot Cuts Risk for Death by Half in Heart Failure
Results of a meta-analysis support wider use of the influenza vaccine in patients with heart failure, researchers say.Medscape Medical News (Source: Medscape Cardiology Headlines)
Source: Medscape Cardiology Headlines - March 9, 2018 Category: Cardiology Tags: Cardiology News Source Type: news

Examining U.S. Public Health Preparedness for and Response Efforts to Seasonal Influenza
March 2018 hearing examined the U.S. Department of Health and Human Services'efforts to combat seasonal influenza, develop an effective influenza vaccine, and to prepare a long-term strategy to improve seasonal influenza preparedness. (Source: PHPartners.org)
Source: PHPartners.org - March 9, 2018 Category: International Medicine & Public Health Source Type: news

Notice of Intent to Publish a Funding Opportunity Announcement for Impact of Initial Influenza Exposure on Immunity in Infants (U01 Clinical Trial Not Allowed)
The National Institute of Allergy and Infectious Diseases (NIAID) is issuing this Notice to promote a new initiative that will solicit applications to support research to determine how initial and repeated natural influenza infections and/or influenza vaccinations shape infant and childhood immunity to future influenza exposures, through support of prospective longitudinal human infant cohorts. (Source: PHPartners.org)
Source: PHPartners.org - March 7, 2018 Category: International Medicine & Public Health Source Type: news

Interim Estimates of 2017-18 Influenza Vaccine Effectiveness Interim Estimates of 2017-18 Influenza Vaccine Effectiveness
How effective is this season's influenza vaccine against currently circulating influenza viruses in the US?Morbidity & Mortality Weekly Report (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 7, 2018 Category: Consumer Health News Tags: Infectious Diseases Journal Article Source Type: news

Influenza and MRSA Pneumonia Influenza and MRSA Pneumonia
Dr Paul Auwaerter discusses the antimicrobial options for postinfluenza MRSA pneumonia, and makes the case for a universal flu vaccine.Medscape Infectious Diseases (Source: Medscape Infectious Diseases Headlines)
Source: Medscape Infectious Diseases Headlines - March 5, 2018 Category: Infectious Diseases Tags: Infectious Diseases Commentary Source Type: news

Flu Has ‘ Definitely Peaked ’ Nationally; Remains High In Mass.
By Susan Scutti, CNN (CNN) — Flu has been shown the door in the United States. Illness activity peaked and began to decline during the eighth week of the year, the US Centers for Disease Control and Prevention’s weekly surveillance report indicated Friday. Just 5% of people who visited their doctors did so while complaining of flu-like illness, down from 6.4% the previous week. Caused by viruses, flu is a contagious respiratory illness with mild to severe symptoms that can sometimes lead to death. “We have definitely peaked,” CDC spokeswoman Kristen Nordlund said, quickly adding, “that doesn&r...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - March 3, 2018 Category: Consumer Health News Authors: Health – CBS Boston Tags: Health News Flu Source Type: news

This Year ’s Deadly Flu Season Has Finally Peaked, CDC Says
After months of record-breaking widespread illness, flu season has finally peaked, according to CDC officials. “We have definitely peaked,” CDC spokeswoman Kristen Nordlund told CNN, but “that doesn’t mean we aren’t going to see more flu activity.” Indeed, most states continue to report high or moderate flu activity, according to the CDC’s weekly flu report. Five percent of all outpatient doctor’s visits last week were due to flu-like symptoms, down from 6.4% last week but more than double the non-flu-season average of 2.2%. Seventeen more pediatric deaths were also reported...
Source: TIME: Health - March 2, 2018 Category: Consumer Health News Authors: Jamie Ducharme Tags: Uncategorized flu flu season healthytime onetime public health Source Type: news

Want to Protect Yourself From Getting the Flu? Get Some Sunshine
By now, you probably know the tried-and-true flu prevention strategies: get vaccinated, wash your hands often and try to steer clear of folks who are sick. But new research says there may be another way to stay healthy, and it begins before flu season is even in full swing. Spending more time in the sun in August and September, and thus absorbing more immune-system-boosting vitamin D, may help prevent the flu as fall progresses, according to a new working paper distributed by the National Bureau of Economic Research. A state that sees an unusually high number of sunny days in a given month, the paper says, can also expect ...
Source: TIME: Health - March 2, 2018 Category: Consumer Health News Authors: Jamie Ducharme Tags: Uncategorized healthytime medicine onetime public health Research Source Type: news

FDA Committee Recommends 2018-2019 Influenza Vaccine Strains FDA Committee Recommends 2018-2019 Influenza Vaccine Strains
The FDA's Vaccines and Related Biological Products Advisory Committee chose the influenza vaccine strains for the 2018-2019 season, after disappointing vaccine effectiveness during the 2017-2018 season.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - March 1, 2018 Category: Consumer Health News Tags: Infectious Diseases News Source Type: news

NIH agency's priority: Developing universal flu vaccine
The Nationals Institutes of Health is working on a universal influenza vaccine it hopes will protect people of all ages against multiple flu strains. (Source: Health News - UPI.com)
Source: Health News - UPI.com - February 28, 2018 Category: Consumer Health News Source Type: news

Why Flu Outbreaks Have Been the Worst in Nearly a Decade
The only thing worse than getting the flu is catching it after you’ve gotten a flu shot. It’s been a terrible year for outbreaks — the worst in almost a decade. Contributing to that is the high failure rate of this year’s vaccine. The current shot is just 25 percent effective against the H3N2 virus, this season’s most-often-identified strain by the Centers for Disease Control and Prevention. The experts say, with enough time and money, they can do a lot better. “There has to be a wholesale change to how we make the flu vaccine,” said Amesh Adalja, senior scholar at Johns Hopkins Ce...
Source: TIME: Science - February 28, 2018 Category: Science Authors: Bloomberg Tags: Uncategorized Bloomberg flu healthytime onetime Source Type: news

NIAID unveils strategic plan for developing a universal influenza vaccine
Developing a vaccine that can provide durable protection for all age groups against multiple influenza strains is a priority. (Source: National Institutes of Health (NIH) News Releases)
Source: National Institutes of Health (NIH) News Releases - February 28, 2018 Category: American Health Source Type: news

Getting flu vaccine cuts risk of death by half in people with heart failure
(American College of Cardiology) For people with heart failure, getting a seasonal influenza (flu) vaccine in a given year was associated with a 50 percent drop in the risk of death during flu season and a 20 percent drop in the risk of death during the rest of the year, according to research presented at the American College of Cardiology's 67th Annual Scientific Session. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 28, 2018 Category: International Medicine & Public Health Source Type: news

NIAID unveils strategic plan for developing a universal influenza vaccine
(NIH/National Institute of Allergy and Infectious Diseases) Developing a universal influenza vaccine -- a vaccine that can provide durable protection for all age groups against multiple strains, including those that might cause a pandemic -- is a priority for the National Institute of Allergy and Infectious Diseases. Writing in the Journal of Infectious Diseases, NIAID officials detail the Institute's new strategic plan for addressing the research areas essential to creating a safe and effective universal influenza vaccine. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - February 28, 2018 Category: Infectious Diseases Source Type: news

Amid bad flu season, FDA working on next year's vaccine
In a year where the influenza vaccine is just 25 percent effective, officials want to make sure next year's flu shot works better (Source: Health News: CBSNews.com)
Source: Health News: CBSNews.com - February 27, 2018 Category: Consumer Health News Source Type: news

The Flu Outbreak Has Peaked but Still Has Weeks to Go
Although the infection rate is in decline, many have been hospitalized and there will be more deaths before this severe flu season finally ends. (Source: NYT Health)
Source: NYT Health - February 26, 2018 Category: Consumer Health News Authors: DONALD G. McNEIL Jr. Tags: Influenza Epidemics Vaccination and Immunization Centers for Disease Control and Prevention United States Source Type: news

ACIP: LAIV OK to Use During 2018-19 Flu Season
The CDC's Advisory Committee on Immunization Practices recently voted 12-2 to recommend that live attenuated influenza vaccine be included among vaccines to be used during the upcoming flu season. (Source: AAFP News)
Source: AAFP News - February 26, 2018 Category: Primary Care Source Type: news

Statement from FDA Commissioner Scott Gottlieb, M.D., on FDA ’s ongoing efforts to help improve effectiveness of influenza vaccines
FDA provides update on flu vaccines during this severe flu season (Source: Food and Drug Administration)
Source: Food and Drug Administration - February 26, 2018 Category: American Health Source Type: news

Statement from FDA Commissioner Scott Gottlieb, M.D., on FDA ’ s ongoing efforts to help improve effectiveness of influenza vaccines
FDA provides update on flu vaccines during this severe flu season (Source: Food and Drug Administration)
Source: Food and Drug Administration - February 26, 2018 Category: American Health Source Type: news