How Often Should Immunocompromised People Get a COVID Booster?
(MedPage Today) -- Preventing SARS-CoV-2 infection in immunocompromised people hasn't gotten any easier as the pandemic trundles on into its fifth year. The monoclonal antibody tixagevimab-cilgavimab (Evusheld) has long gone by the wayside for... (Source: MedPage Today Infectious Disease)
Source: MedPage Today Infectious Disease - March 18, 2024 Category: Infectious Diseases Source Type: news

How HHS Plans to Fight Increases in Syphilis, Maternal Mortality
(MedPage Today) -- fIn this exclusive video interview, MedPage Today editor-in-chief Jeremy Faust, MD, talks with Admiral Rachel Levine, MD, the assistant secretary for health at the Department of Health and Human Services (HHS), about how HHS... (Source: MedPage Today Infectious Disease)
Source: MedPage Today Infectious Disease - March 14, 2024 Category: Infectious Diseases Source Type: news

Paul Alexander Thrived for Decades in an Iron Lung After Contracting Polio in 1952
(MedPage Today) -- Confined to an iron lung after contracting polio as a child, Paul Alexander managed to train himself to breathe on his own for part of the day, earned a law degree, wrote a book about his life, built a big following on social... (Source: MedPage Today Infectious Disease)
Source: MedPage Today Infectious Disease - March 14, 2024 Category: Infectious Diseases Source Type: news

Published Data Show Why GSK Bailed on Its Maternal RSV Vaccine
(MedPage Today) -- GSK's abandoned maternal respiratory syncytial virus (RSV) vaccine protected infants from severe RSV, final results of a phase III trial indicated, but those positive outcomes came at the expense of an unexplained higher risk... (Source: MedPage Today Infectious Disease)
Source: MedPage Today Infectious Disease - March 14, 2024 Category: Infectious Diseases Source Type: news

Most People With TB Report No Persistent Cough
(MedPage Today) -- A significant proportion of people in the community with pulmonary tuberculosis (TB) have subclinical disease, according to a meta-analysis involving survey studies across Africa and Asia. In adjusted analyses, 82.8% (95% CI... (Source: MedPage Today Infectious Disease)
Source: MedPage Today Infectious Disease - March 13, 2024 Category: Infectious Diseases Source Type: news

Dapivirine Vaginal Ring, Oral PrEP Safe for HIV Prevention in Pregnancy
(MedPage Today) -- DENVER -- The monthly dapivirine ring to reduce risk of HIV in women showed similar safety outcomes as oral pre-exposure prophylaxis (PrEP) when used throughout the second and third trimesters of pregnancy, according to a phase... (Source: MedPage Today Infectious Disease)
Source: MedPage Today Infectious Disease - March 12, 2024 Category: Infectious Diseases Source Type: news

A Health System in Critical Condition
(MedPage Today) -- When I started keeping a detailed diary in February 2020, I was a pediatric surgery fellow at one of New York City's top hospitals in the home stretch of nearly a decade of medical training. I had just signed the contract for... (Source: MedPage Today Infectious Disease)
Source: MedPage Today Infectious Disease - March 12, 2024 Category: Infectious Diseases Source Type: news

Novel Short-Duration TB Treatment Fizzles
(MedPage Today) -- DENVER -- Most patients with tuberculosis (TB) who received a treatment regimen that included the repurposed leprosy drug clofazimine converted to negative sputum cultures after 12 weeks, but a substantial proportion went on... (Source: MedPage Today Infectious Disease)
Source: MedPage Today Infectious Disease - March 11, 2024 Category: Infectious Diseases Source Type: news

Once-Weekly ART Showed Similar Efficacy for HIV as Daily ART
(MedPage Today) -- DENVER -- A once-weekly oral antiretroviral therapy (ART) regimen of the investigational drug islatravir, a nucleoside reverse transcriptase translocation inhibitor, with lenacapavir (Sunlenca) showed similar efficacy to daily... (Source: MedPage Today Infectious Disease)
Source: MedPage Today Infectious Disease - March 11, 2024 Category: Infectious Diseases Source Type: news

Triplet Regimen Shortens Effective TB Treatment
(MedPage Today) -- DENVER -- Combining the investigational drug quabodepistat with established anti-tuberculosis (TB) drugs delamanid and bedaquiline resulted in comparable efficacy over 4 months as a standard four-drug regimen over 6 months... (Source: MedPage Today Infectious Disease)
Source: MedPage Today Infectious Disease - March 11, 2024 Category: Infectious Diseases Source Type: news

Rapid PCR Tests for Pneumonia in the ED Speed Up Targeted Treatment
(MedPage Today) -- For people with suspected community-acquired pneumonia (CAP) in the emergency department (ED), routine polymerase chain reaction (PCR) testing on lower respiratory tract samples led to faster and more targeted treatment, according... (Source: MedPage Today Infectious Disease)
Source: MedPage Today Infectious Disease - March 8, 2024 Category: Infectious Diseases Source Type: news

Alpibectir-Ethionamide Safe for TB, With Similar Activity to Isoniazid
(MedPage Today) -- DENVER -- In patients with tuberculosis (TB), a novel fixed-dose combination of alpibectir-ethionamide had similar levels of bactericidal activity as isoniazid, with no serious adverse events and good tolerability, a phase... (Source: MedPage Today Infectious Disease)
Source: MedPage Today Infectious Disease - March 7, 2024 Category: Infectious Diseases Source Type: news

Steep Decline in Chlamydia, Syphilis Rates 'Seals the Case' for DoxyPEP
(MedPage Today) -- DENVER -- Chlamydia and early syphilis cases among at-risk individuals were halved after the introduction of doxycycline post-exposure prophylaxis (doxyPEP), real-world data from San Francisco showed. Over a 13-month period... (Source: MedPage Today Infectious Disease)
Source: MedPage Today Infectious Disease - March 6, 2024 Category: Infectious Diseases Source Type: news

Wonky Period After COVID Vaccine May Only Happen During One Phase
(MedPage Today) -- Women vaccinated against COVID-19 during the follicular phase of their period had their next cycle last 1 day longer than normal, according to a retrospective cohort analysis of menstrual cycle data. That increase was 1.00 day... (Source: MedPage Today Infectious Disease)
Source: MedPage Today Infectious Disease - March 4, 2024 Category: Infectious Diseases Source Type: news

COVID-19 Tied to Increased Risk for Rheumatic Disease
(MedPage Today) -- Rates of new-onset autoimmune inflammatory rheumatic disease (AIRD) such as rheumatoid arthritis and systemic lupus erythematosus were significantly increased following bouts of COVID-19 in South Korea and Japan, researchers... (Source: MedPage Today Infectious Disease)
Source: MedPage Today Infectious Disease - March 4, 2024 Category: Infectious Diseases Source Type: news