NIH FDA COVID-19 SIG Lecture Series- Professor Wendy Barclay
Dr. Barclay joined Imperial College in May 2007, moving with her research group from the University of Reading where she had previously been based since 1995. She had graduated in Natural Sciences from Cambridge University and had undertaken my PhD at the Common Cold Unit, Salisbury under the joint supervision of Dr David Tyrrell and Dr Fred Brown, studying the human immune response to rhinovirus. Dr. Barclay acquired molecular virology skills as a postdoctoral fellow first in the laboratories of Professor Jeff Almond at Reading and then working with Dr Peter Palese at the Mount Sinai School of Medicine, New York.Dr. Barcl...
Source: Videocast - All Events - December 4, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video
The dark side of DNA - how the immune system senses DNA as a danger signal
Zhijian “ James ” Chen ’ s research into complex cellular biochemistry has led to the discovery of pathways and proteins that trigger immune and stress responses. Chen has identified proteins, such as the mitochondrial protein MAVS, that are crucial to the body ’ s defense against RNA viruses such as influenza and Ebola. Now, Chen and his team are dissecting a signaling pathway involving a novel DNA sensor – cyclic GMP-AMP (cGAMP) synthase, or cGAS – which activates an interferon response that may play a role in immune defense against pathogens and malignant cells, as well as in autoimmune diseases such as lupu...
Source: Videocast - All Events - July 26, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video
Influenza Pathogenesis and Therapeutics in Vulnerable Populations
Established in 1950 in honor of former NIH Director Rolla E. Dyer, M.D., a noted authority on infectious diseases, this lectureship, now part of the Wednesday Afternoon Lecture Series, features internationally renowned researchers who have contributed substantially to medical as well as biological knowledge of infectious diseases. The Dyer Lecture is the oldest continuous lecture series at the NIH.
Stacey Schultz-Cherry, PhD, is a Full Member and Professor in the Department of Infectious Diseases at St Jude Children ’ s Research Hospital in Memphis, TN as well as Senior Associate Dean for the St Jude Graduate School of...
Source: Videocast - All Events - July 19, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video
Interpreting the Evolution of SARS-CoV-2
COVID-19 SIG
SARS-CoV-2 has undergone rapid antigenic evolution over the last few years. I will discuss how the patterns of SARS-CoV-2 evolution compare to other human respiratory viruses. I will also discuss how high-throughput deep mutational scanning experiments can help us interpret the ongoing evolution and get some idea of what might come next Presentation objectives: Explain the different ways that human respiratory viruses evolve in response to immune pressure. Explain how deep mutational scanning can be used to understand the effects of viral mutations. Explain how experimental data can be used to interpret and to...
Source: Videocast - All Events - November 9, 2022 Category: General Medicine Tags: Upcoming Events Source Type: video
COVID-19 SIG talk with Jesse Bloom
Dr. Jesse Bloom studies evolution using viruses and viral proteins as models. Specifically focusing on the fast-evolving influenza virus, Bloom aims to understand how mutations in viral genes shape the pathogen ’ s ability to infect and spread. He uses computational biology and real-world data to build evolutionary models and examine different scales of viral evolution, from evolution within a single host to evolution on a global scale. In doing so, Bloom addresses both fundamental and translational questions, including those with relevance to developing more effective seasonal flu vaccines.For more information go tohttp...
Source: Videocast - All Events - August 29, 2022 Category: General Medicine Tags: Upcoming Events Source Type: video
Strategies for Development of Coronavirus Vaccines That Induce Broadly Reactive Neutralizing Antibodies
Speaker Barton Ford Haynes is Professor of Medicine Frederic M. Hanes Distinguished Professor of Medicine at Duke University. The Haynes lab is studying host innate and adaptive immune responses to the human immunodeficiency virus (HIV), tuberculosis (TB), and influenza in order to find the enabling technology to make preventive vaccines against these three major infectious diseases.For more information go tohttps://www.niaid.nih.gov/research/covid-19-sigAir date: 11/18/2021 12:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - September 21, 2021 Category: General Medicine Tags: Upcoming Events Source Type: video
Evolutionary Dynamics of SARS-CoV-2
This is the annual Dewitt Stetten Jr. Lecture. Speaker Trevor Bedford, Ph.D., is Associate Professor, Vaccine and Infectious Disease Division; Associate Professor, Herbold Computational Biology Program; and Associate Professor, Human Biology Division, Fred Hutch. Bedford uses powerful computers and complex statistical methods to study the rapid spread and evolution of viruses, including those that cause COVID-19, influenza, Ebola and Zika. Data gathered from these processes help researchers develop successful strategies for monitoring and controlling infectious diseases.For more information go tohttps://oir.nih.gov/walsAir...
Source: Videocast - All Events - September 8, 2021 Category: General Medicine Tags: Upcoming Events Source Type: video
Kinyoun Lecture: Structure-Assisted Design of Universal Vaccines and Therapeutics Against Influenza Virus
Kinyoun Lecture
Ian A. Wilson, D. Phil., D.Sc., Hansen professor of structural biology and chair, department of integrative structural and computational biology at The Scripps Research Institute, La Jolla, Calif., will deliver the 2019 Joseph J. Kinyoun Memorial Lecture on Tuesday, November 19, at 3 p.m. in Lipsett Amphitheater, Bldg. 10. His presentation is titled, “ Structure-assisted Design of Universal Vaccines and Therapeutics against Influenza Virus. ”
Wilson will explain how insights gained through structural biology approaches are aiding in devising new ways to treat or prevent influenza. The health and economi...
Source: Videocast - All Events - November 12, 2019 Category: General Medicine Tags: Upcoming Events Source Type: video
How to bust up a bacterial biofilm
NIH Director's Wednesday Afternoon Lecture Series
The Bakaletz laboratory ’ s research focus is attempting to understand the pathogenic mechanisms operational in the highly prevalent pediatric disease, otitis media (OM) (or middle ear infection). Specifically, we are interested in elucidating how upper respiratory tract viruses predispose the middle ear to invasion by any of the three predominant bacterial pathogens of OM (nontypeable Haemophilus influenzae, Moraxella catarrhalis and Streptococcus pneumoniae). We are also interested in understanding how bacterial biofilms contribute to the recurrence and chronicity of OM...
Source: Videocast - All Events - March 25, 2019 Category: General Medicine Tags: Upcoming Events Source Type: video
The Mother (of all Pandemics) and Her Naughty Children: 100 Years of Behaving Badly
Writing in his diary on September 27, 1918, Charles Corning, former mayor of Concord, New Hampshire, described how flu was blazing through his corner of the world “ as fire shrivels the fields, laying out communities and taking a toll of death unprecedented. ” The next day, he observed, “ A heavy sense of anxiety and apprehension like a dismal cloud in midsummer weighs heavily upon us because of the deadly ravages of the so-called Spanish influenza. Funerals jostle one another so the sable procession goes on. ” That sable procession would eventually claim 167 lives in Concord and at least 50 million more around the...
Source: Videocast - All Events - April 3, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video
Vaccines and Related Products Advisory Committee (VRBPAC)
FDA/CBER Advisory Committee Program
145th Meeting of the VRBPAC – Strain Selection for the Influenza Virus Vaccines for the 2017-2018 Influenza SeasonAir date: 3/9/2017 8:30:00 AM (Source: Videocast - All Events)
Source: Videocast - All Events - February 13, 2017 Category: Journals (General) Tags: Upcoming Events Source Type: video
2016 Kinyoun Lecture - Structure-Based Vaccine Design and B-cell Ontogeny in the Modern Era of Vaccinology
2016 Joseph J. Kinyoun Memorial Lecture
Dr. John Mascola, director of the Dale and Betty Bumpers Vaccine Research Center at NIAID, will deliver the 2016 Joseph J. Kinyoun Memorial Lecture.
His talk, titled “ Structure-Based Vaccine Design and B-cell Ontogeny in the Modern Era of Vaccinology, ” will include an overview of the challenges facing the development of effective vaccines against viruses, including HIV, respiratory syncytial virus and influenza virus. Mascola will describe how researchers can use structural information about viral proteins and antiviral antibodies to design new vaccines. He also will discuss ho...
Source: Videocast - All Events - November 29, 2016 Category: Journals (General) Tags: Upcoming Events Source Type: video
CC Grand Rounds: (1) Healthy Volunteer Human Influenza Challenge Model: A Key Piece of The Universal Vaccine Puzzle and (2) Development and Pre-Clinical Evaluation of a Virus-like Particle (VLP) Universal Influenza Vaccine
Presented by: (1) Matthew J. Memoli, MD, MS Director, Clinical Studies Unit, Viral Pathogenesis and Evolution Section, Laboratory of Infectious Diseases, NIAID, NIH and (2) Jeffery K. Taubenberger, MD, PhD Chief, Viral Pathogenesis and Evolution Section, LaboratorCategory: Clinical Center Grand RoundsAired date: 03/30/2016 (Source: Videocast - All Events)
Source: Videocast - All Events - March 31, 2016 Category: Journals (General) Tags: Past Events Source Type: video
Clonal and Cellular Dynamics in Germinal Centers.
Immunology Interest Group
A native of Brazil, Gabriel Victora has a Bachelor and Master's degree in classical piano from the Mannes College of Music in New York City, a Master in Immunology from the University of Sao Paulo, Brazil, and a Ph.D. in Immunology from the New York University Medical School. For the last ten years, his work has focused on B lymphocytes, especially on how antibody affinity matures in the germinal center. This work has earned him the Weintraub Award for graduate research, the Science Magazine/SciLifeLab prize for young scientists (Molecular Biology category), an NIH Director's Early Independence A...
Source: Videocast - All Events - March 17, 2016 Category: Journals (General) Tags: Upcoming Events Source Type: video
CC Grand Rounds: (1) Healthy Volunteer Human Influenza Challenge Model: A Key Piece of The Universal Vaccine Puzzle and (2) Development and Pre-Clinical Evaluation of a Virus-like Particle (VLP) Universal Influenza Vaccine
For more information go to http://www.cc.nih.gov/about/news/grcurrent.htmlAir date: 3/30/2016 12:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - February 19, 2016 Category: Journals (General) Tags: Upcoming Events Source Type: video
