Gene therapy promotes nerve regeneration
(Netherlands Institute for Neuroscience - KNAW) Researchers from the Netherlands Institute for Neuroscience and the Leiden University Medical Center have shown that treatment using gene therapy leads to a faster recovery after nerve damage. By combining a surgical repair procedure with gene therapy, the survival of nerve cells and regeneration of nerve fibers over a long distance was stimulated. The discovery, published in Brain, is an important step towards the development of a new treatment for people with nerve damage. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - January 18, 2019 Category: International Medicine & Public Health Source Type: news

Opioid Use in Pregnancy Linked to Birth Defects?
Researchers recently found that counties that had higher rates of opioid prescribing had nearly two times more babies born with their intestines outside of their bodies, a condition known as gastroschisis, compared with counties with low opioid prescribing rates. (Source: WebMD Health)
Source: WebMD Health - January 17, 2019 Category: Consumer Health News Source Type: news

Opioid Use in Pregnancy Tied to Severe Birth Defects
THURSDAY, Jan. 17, 2019 -- More American infants are being born with their intestines outside of their bodies, and the disturbing trend might be linked to the opioid crisis, health officials reported Thursday. The condition, called gastroschisis, is... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - January 17, 2019 Category: General Medicine Source Type: news

Abbott Finally Pulls the Trigger on Cephea Acquisition
It was only a matter of time before Abbott Laboratories exercised its option to acquire Cephea Valve Technologies, a company it first invested in back in 2015. The Abbott Park, IL-based company announced on Wednesday it would acquire the mitral valve maker for an undisclosed sum. Cephea's technology is being developed to provide an option for people whose diseased mitral valves need to be replaced. The artificial valve is designed to be delivered through a vein in the leg, forgoing the need for open-heart surgery. Replacement of the diseased mitral valve restores normal blood flow through the heart. "The acquisition o...
Source: MDDI - January 17, 2019 Category: Medical Devices Authors: Omar Ford Tags: Cardiovascular Business Source Type: news

Edwards and Boston Sci End TAVR Patent Dispute
Edwards Lifesciences is resolving its longstanding dispute with Boston Scientific over transcatheter aortic valve replacement (TAVR) patents. However, this time the Irvine, CA-based company is on the other side of the lawsuit coin and is poised to dole out a one-time payment of $180 million to Boston Scientific. Both companies said that no further royalty fees will be owed by any company. In addition, both companies said that all pending cases or appeals in courts and patent offices will be dismissed, and the parties will not litigate patent disputes related to current portfolios of transcatheter aortic valves, certain mit...
Source: MDDI - January 15, 2019 Category: Medical Devices Authors: Omar Ford Tags: Business Cardiovascular Source Type: news

Edwards Lifesciences pays $180m to bury the hatchet with Boston Scientific
Boston Scientific (NYSE:BSX) and Edwards Lifesciences (NYSE:EW) said today that they’re burying the hatchet, settling their worldwide patent war over cardiac valve and implant technology, with Edwards paying $180 million to end the dispute. “All pending cases or appeals in courts and patent offices between the two companies will be dismissed, and the parties will not litigate patent disputes related to current portfolios of transcatheter aortic valves, certain mitral valve repair devices, and left atrial appendage closure devices. Any injunctions currently in place will be lifted,” the companies...
Source: Mass Device - January 15, 2019 Category: Medical Devices Authors: Brad Perriello Tags: Cardiac Implants Featured Legal News Replacement Heart Valves Wall Street Beat Boston Scientific Edwards Lifesciences Source Type: news

Cadherin-11-mediated adhesion of macrophages to myofibroblasts establishes a profibrotic niche of active TGF-{beta}
Macrophages contribute to the activation of fibroblastic cells into myofibroblasts, which secrete collagen and contract the collagen matrix to acutely repair injured tissue. Persistent myofibroblast activation leads to the accumulation of fibrotic scar tissue that impairs organ function. We investigated the key processes that turn acute beneficial repair into destructive progressive fibrosis. We showed that homotypic cadherin-11 interactions promoted the specific binding of macrophages to and persistent activation of profibrotic myofibroblasts. Cadherin-11 was highly abundant at contacts between macrophages and myofibrobla...
Source: Signal Transduction Knowledge Environment - January 15, 2019 Category: Science Authors: Lodyga, M., Cambridge, E., Karvonen, H. M., Pakshir, P., Wu, B., Boo, S., Kiebalo, M., Kaarteenaho, R., Glogauer, M., Kapoor, M., Ask, K., Hinz, B. Tags: STKE Research Articles Source Type: news

Poor Sleep Linked To Dangerous Plaque Buildup In Arteries
By Sandee LaMotte, CNN (CNN) — Here’s another reason why getting a good night’s sleep should be on your must-do list: Sleeping fewer than six hours a night or waking frequently raises your risk of developing damaging plaque in arteries throughout your body, not just your heart. Previous research has shown poor sleep to be strongly associated with coronary heart disease, but “This is the first study to show that objectively measured sleep is independently associated with atherosclerosis throughout the body,” José Ordovás, director of nutrition and genomics at the Jean Mayer USDA H...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - January 14, 2019 Category: Consumer Health News Authors: Health – CBS Boston Tags: Boston News Health CNN Heart Disease Sleep Tufts University Source Type: news

Abbott wins FDA approval for Amplatzer Piccolo occluder for neonates
The FDA granted pre-market approval for the Amplatzer Piccolo occluder made by Abbott (NYSE:ABT) to treat a congenital heart defect in neonatal infants as small as two pounds, the company said today. The Chicago-area healthcare giant said Amplatzer Piccolo is a transcatheter, self-expanding, wire mesh device that’s inserted via the aortic or pulmonary artery to close a hole in the heart known as patent ductus arteriosus. “Piccolo is a critical advancement in the standard of care for the most vulnerable of premature babies who may not be able to undergo surgery to repair their hearts,” structural...
Source: Mass Device - January 14, 2019 Category: Medical Devices Authors: Brad Perriello Tags: Cardiac Implants Featured Food & Drug Administration (FDA) Pediatrics Abbott Source Type: news

Olympus rejiggers medical biz
Olympus (TYO:7733) last week announced its plan to rejigger its medical device business with an eye toward gaining share in the U.S. market. The Japanese conglomerate weathered an accounting scandal in 2011 after firing its first foreign CEO, Michael Woodford, after he blew the whistle on unexplained payments worth around $1.7 billion and demanded the resignation of the former chairman and vice president. In September 2012 the company and 3 former executives pleaded guilty in Japan to cover-up charges. By 2014 Olympus was caught up in an FDA warning about power morcellators, whi...
Source: Mass Device - January 14, 2019 Category: Medical Devices Authors: Brad Perriello Tags: Endoscopic / Arthroscopic Featured Wall Street Beat Olympus Source Type: news

MANF identified as a rejuvenating factor in parabiosis
(Buck Institute for Research on Aging) Older mice who are surgically joined with young mice in order to share a common bloodstream get stronger and healthier, making parabiosis one of the hottest topics in age research. Publishing in Nature Metabolism, researchers report that MANF (mesencephalic astrocyte-derived neurotrophic factor) is one of the factors responsible for rejuvenating the transfused older mice. Researchers also show the naturally occurring, evolutionarily conserved repair mechanism protects against liver damage in aging mice and extends lifespan in flies. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - January 14, 2019 Category: International Medicine & Public Health Source Type: news

Doing more with less
(University of Freiburg) In adults, mesenchymal stems cells (MSCs) are primarily found in bone marrow and they play a vital role in repair of damaged organs. The transformation of a single MSC into complex tissue like cartilage and bone starts with its association with other MSCs in order to form microscopic clusters via a process termed as condensation. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - January 14, 2019 Category: International Medicine & Public Health Source Type: news

Tela Bio, Aroa Biosurgery win FDA nod for large-size OviTex bioscaffolds
Tela Bio and its partner Aroa Biosurgery said yesterday that it won FDA 510(k) clearance for large-size OviTex reinforced bioscaffolds intended for soft tissue repair. The OviTex RBS devices are surgical implants with integrated biologic and synthetic materials to allow the movement of fluid and cells through the product, Malvern, Penn.-based Tela Bio said. With the clearance, the companies said that they will now offer the OviTex RBS devices in the US in sizes up to 20×40 cm, a 150% surface area increase over its currently available offerings. “We are pleased to launch larger OviTex RBSs as we continue our mis...
Source: Mass Device - January 11, 2019 Category: Medical Devices Authors: Fink Densford Tags: Featured Food & Drug Administration (FDA) Regenerative Medicine Regulatory/Compliance aroabiosurgery Tela Bio Source Type: news

Bone adhesive dev Launchpad Medical raises $9m | Medtech Funding Roundup
Launchpad Medical has raised $8.5 million in a new round of equity financing, according to recently posted SEC filings. The Lowell, Mass.-based medtech company is developing the Tetranite injectable, synthetic adhesive solution intended for bone repair. Tetranite is bioresorbable and is designed to provide instant adhesive capabilities to treat fractured bone and to stabilize metal hardware in compromised bone, according to the company’s website. The company is looking to raise an additional $1 million in the round, which would bring the total raised to $9.5 million. The round was joined by 71 unnamed investors, acco...
Source: Mass Device - January 10, 2019 Category: Medical Devices Authors: Fink Densford Tags: Business/Financial News Featured Wall Street Beat ALung Technologies Inc. babyscripts BioCardia conextionsmedical Conventus Orthopaedics cynerio decisionsciencesmedical Jarvik Heart launchpadmedical Leviticus Cardio royalphilips Source Type: news

New Method Could Lead to Materials to Promote Natural Healing
A team of researchers from the Imperial College in London have created a new process known as traction force-activated payloads (TrAPs) that could have an impact on the body’s ability to heal. The method, developed by Dr. Ben Almquist and a team at Imperial College London, allows materials to speak to the body’s natural repair systems to drive healing. In the TrAPs process, researchers folded DNA segments into 3-D shapes known as aptamers that cling tightly to proteins. Then, the researchers attached a customizable ‘handle’ that cells can grab onto on ...
Source: MDDI - January 8, 2019 Category: Medical Devices Authors: MDDI Staff Tags: Materials Source Type: news

'Bio-scaffold' that could speed by the healing of wounds has been created by scientists   
In a world first, scientists at Imperial College London have designed materials that 'talk' to the body's injured tissue to support its repair through every stage of the healing process. (Source: the Mail online | Health)
Source: the Mail online | Health - January 8, 2019 Category: Consumer Health News Source Type: news

Return to work after early repair of acute traumatic rotator cuff tears - Aagaard KE, Randeblad P, Abu-Zidan FM, Lunsjo K.
BACKGROUND: Lost workdays following rotator cuff repair is not well-studied in the literature. We aimed to define the time away from work following early arthroscopic repair of acute traumatic rotator cuff tears and compare it with the recommendations of t... (Source: SafetyLit)
Source: SafetyLit - January 8, 2019 Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news

German hospitals are first to use Wayne firm's blood-vessel repair system
Intact Vascular Inc., a Wayne-based developer of medical devices, said Monday it has launched its Tack Endovascular System in the European Union, where the product's first commercial use has taken place at multiple hospitals in Germany. Dr. Michael K.W. Lichtenberg, chief of Klinkum Arnsberg, an angiology clinic and venous center in Germany, said based on his initial experience with system he believes it will become standard of care for patients undergoing peripheral artery disease interventions.… (Source: bizjournals.com Health Care:Pharmaceuticals headlines)
Source: bizjournals.com Health Care:Pharmaceuticals headlines - January 8, 2019 Category: Pharmaceuticals Authors: John George Source Type: news

German hospitals are first to use Wayne firm's blood-vessel repair system
Intact Vascular Inc., a Wayne-based developer of medical devices, said Monday it has launched its Tack Endovascular System in the European Union, where the product's first commercial use has taken place at multiple hospitals in Germany. Dr. Michael K.W. Lichtenberg, chief of Klinkum Arnsberg, an angiology clinic and venous center in Germany, said based on his initial experience with system he believes it will become standard of care for patients undergoing peripheral artery disease interventions.… (Source: bizjournals.com Health Care:Biotechnology headlines)
Source: bizjournals.com Health Care:Biotechnology headlines - January 8, 2019 Category: Biotechnology Authors: John George Source Type: news

AtriCure falls despite solid Q4, 2018 prelims | Wall Street Beat
AtriCure (NSDQ:ATRC) shares took a fall today despite preliminary results for the fourth quarter and 2018 that topped estimates. The Mason, Ohio-based cardiac implant maker said it expects to post Q4 sales of $52.9 million and 2018 sales of $201.6 million, beating the consensus estimatyes on Wall Street for both periods. “We are pleased with our fourth quarter results and performance throughout 2018, as we continue our track record of strong, consistent revenue growth. We achieved many milestones and accomplishments in 2018: we completed enrollment in the Converge IDE trial, trained over 400 healthcare professio...
Source: Mass Device - January 7, 2019 Category: Medical Devices Authors: Brad Perriello Tags: Featured MassDevice Earnings Roundup Wall Street Beat AtriCure Inc. AxoGen Cerus Corp. OrthoPediatrics Corp. Sientra STAAR Surgical Co Source Type: news

Endologix Voluntarily Recalls Nellix
Endologix said it was initiating a voluntary recall of the existing inventory of its Nellix endovascular aneurysm sealing system. The Irvine, CA-based company said it was limiting the device to only be available for use under clinical protocol with pre-screened patients that adhere to the current indications. Endologix said it was taking these steps in order to ensure optimal outcomes for patients. This decision is one of several actions taken by Endologix following a new management mandate in August 2018 to ensure the most appropriate use of each of its devices and is in alignment with a recent publication by the European...
Source: MDDI - January 6, 2019 Category: Medical Devices Authors: Omar Ford Tags: Cardiovascular Regulatory and Compliance Source Type: news

The road to a healthier heart: Study suggests using TCM to repair mitochondrial dysfunction
(Natural News) Ischemic heart disease, which is also called coronary heart disease, is the most prevalent and the deadliest heart problem in the U.S. According to the Centers for Disease Control and Prevention (CDC), this disease causes more than 370,000 deaths yearly. Moreover, ischemic heart disease also increases the risk of heart attacks. These cause further damage to... (Source: NaturalNews.com)
Source: NaturalNews.com - January 6, 2019 Category: Consumer Health News Source Type: news

Human injuries risk assessment of medium voltage electrocution using bow tie model in fuzzy environment (case study: golestan province electricity distribution company) - Babaei MM, Jabbari M, Babaei AA.
Individuals involved in development, repair and maintenance activities of power transmission and distribution are at high risk of electrocution. The purpose of this research is to calculate the human injuries risk of medium voltage electrocution accidents ... (Source: SafetyLit)
Source: SafetyLit - January 4, 2019 Category: International Medicine & Public Health Tags: Burns, Electricity, Explosions, Fire, Scalds Source Type: news

Carbon is GOOD: MIT chemical engineers create a material that can repair itself using carbon from the air
(Natural News) Airborne carbon can one day serve as a resource to repair damage, maintain structural integrity, or even build entirely new parts. An article in Nanowerks reported the development of a polymer that can absorb carbon dioxide and make use of the resource to improve or expand itself. The new material is similar to... (Source: NaturalNews.com)
Source: NaturalNews.com - January 4, 2019 Category: Consumer Health News Source Type: news

Book Review: Struggle Well: Thriving in the Aftermath of Trauma
Like me, you’ve probably seen people crumble and fail to recover from trauma (big or small) and you’ve also probably seen others who come through their experiences with clearer eyes, stronger spirits, straighter backs, and deeper wells of empathy and compassion. Perhaps they are even able to use their experiences in profoundly creative ways. The Japanese concept of kintsugi treats breakage and repair as part of the history of an object rather than something to disguise. People can be proud of their scars, and some even transform them into memoir or service, or embellish them literally with tattoos and other ap...
Source: Psych Central - January 3, 2019 Category: Psychiatry Authors: Lori Handelman, PhD Tags: Book Reviews Disorders General Memory and Perception Personal Stories Psychology PTSD Self-Help Trauma Treatment combat Falke Goldberg Struggle Well Therapy veteran Source Type: news

Former Rotation Medical CEO Shadan joins Miach Ortho | Personnel Moves – January 3, 2019
Early stage medtech firm Miach Orthopaedics said today that it named former Rotation Medical CEO and medtech vet Martha Shadan as its new prez and chief executive officer. Shadan has held numerous leadership positions at medtech firms, including Zimmer Biomet (NYSE:ZBH), Covidien, Bristol Myers Squibb and Merck, Westborough, Mass.-based Miach said. Prior to joining Miach, Shadan lead rotator cup repair device firm Rotation Medical, which was acquired by Smith & Nephew for $210 million in December 2017. Shadan has also served as exec chairwoman of Miach’s board of directors since September last year, the comp...
Source: Mass Device - January 3, 2019 Category: Medical Devices Authors: Fink Densford Tags: Business/Financial News Featured cathworks Endotronix Inc. iCad Inc. lightmed Miach Orthopaedics Nephros Nobilis Health Nuvasive Obalon Therapeutics Personnel Moves Repro Med Systems rotationmedical Tela Bio Source Type: news

Former Rotation Medical CEO Shadan joines Miach Ortho | Personnel Moves – January 3, 2019
Early stage medtech firm Miach Orthopaedics said today that it named former Rotation Medical CEO and medtech vet Martha Shadan as its new prez and chief executive officer. Shadan has held numerous leadership positions at medtech firms, including Zimmer Biomet (NYSE:ZBH), Covidien, Bristol Myers Squibb and Merck, Westborough, Mass.-based Miach said. Prior to joining Miach, Shadan lead rotator cup repair device firm Rotation Medical, which was acquired by Smith & Nephew for $210 million in December 2017. Shadan has also served as exec chairwoman of Miach’s board of directors since September last year, the comp...
Source: Mass Device - January 3, 2019 Category: Medical Devices Authors: Fink Densford Tags: Business/Financial News Featured cathworks Endotronix Inc. iCad Inc. lightmed Miach Orthopaedics Nephros Nobilis Health Nuvasive Obalon Therapeutics Personnel Moves Repro Med Systems rotationmedical Tela Bio Source Type: news

An Experimental Procedure Could Help More Families Have Healthy Babies. But It ’s Not Allowed in the U.S.
When Noah Shulman was born a few days after Christmas 2016, his parents Kristelle and Evan had no reason to worry about him. The pregnancy went smoothly, and so did the birth. But within a few days of taking his first breath, Noah began to struggle. He wasn’t feeding, so he started losing weight. He was also lethargic. Several pediatricians reassured the Shulmans that they were probably just overly sensitive to Noah’s symptoms because Kristelle is a nurse and Evan is a physician assistant–a case of first-time-parent-white-coat syndrome. “They kind of dismissed us as neurotic parents,” says Eva...
Source: TIME: Health - January 3, 2019 Category: Consumer Health News Authors: Alice Park Tags: Uncategorized fertility Research Source Type: news

An Experimental Procedure Could Help More Families Have Healthy Babies. But It ’s Not Allowed in the U.S.
When Noah Shulman was born a few days after Christmas 2016, his parents Kristelle and Evan had no reason to worry about him. The pregnancy went smoothly, and so did the birth. But within a few days of taking his first breath, Noah began to struggle. He wasn’t feeding, so he started losing weight. He was also lethargic. Several pediatricians reassured the Shulmans that they were probably just overly sensitive to Noah’s symptoms because Kristelle is a nurse and Evan is a physician assistant–a case of first-time-parent-white-coat syndrome. “They kind of dismissed us as neurotic parents,” says Eva...
Source: TIME: Science - January 3, 2019 Category: Science Authors: Alice Park Tags: Uncategorized fertility Research Source Type: news

Commensal-specific T cell plasticity promotes rapid tissue adaptation to injury
Barrier tissues are primary targets of environmental stressors and are home to the largest number of antigen-experienced lymphocytes in the body, including commensal-specific T cells. We found that skin-resident commensal-specific T cells harbor a paradoxical program characterized by a type 17 program associated with a poised type 2 state. Thus, in the context of injury and exposure to inflammatory mediators such as interleukin-18, these cells rapidly release type 2 cytokines, thereby acquiring contextual functions. Such acquisition of a type 2 effector program promotes tissue repair. Aberrant type 2 responses can also be ...
Source: ScienceNOW - January 3, 2019 Category: Science Authors: Harrison, O. J., Linehan, J. L., Shih, H.-Y., Bouladoux, N., Han, S.-J., Smelkinson, M., Sen, S. K., Byrd, A. L., Enamorado, M., Yao, C., Tamoutounour, S., Van Laethem, F., Hurabielle, C., Collins, N., Paun, A., Salcedo, R., OShea, J. J., Belkaid, Y. Tags: Immunology, Online Only r-articles Source Type: news

Genetic Biomarkers Define Subgroup of Likely Prostate Ca ImmunoTx Responders (CME/CE)
(MedPage Today) -- Still, not all microsatellite-high/mismatch repair-deficient patients benefited from pembrolizumab (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - January 2, 2019 Category: Hematology Source Type: news

World surgical first sees 66-year-old blocked heart valve cleared with a live wire up his leg  
Leaky heart valves can leave patients struggling for breath and lead to heart failure. Repair usually involves open heart surgery but Michael Hammond, of Hove, had an alternative. (Source: the Mail online | Health)
Source: the Mail online | Health - January 2, 2019 Category: Consumer Health News Source Type: news

PolarityTE registers bone repair product with FDA
PolarityTE (NSDQ:PTE) said last week that it registered its bone repair product, OsteoTE, with the FDA. The Utah-based company’s technology is an autologous, homologous product designed to repair, reconstruct and replace bone using a patient’s own cells. Get the full story at our sister site, Drug Delivery Business News. The post PolarityTE registers bone repair product with FDA appeared first on MassDevice. (Source: Mass Device)
Source: Mass Device - December 31, 2018 Category: Medical Devices Authors: Sarah Faulkner Tags: Featured Food & Drug Administration (FDA) Regenerative Medicine Regulatory/Compliance Wall Street Beat Wound Care polarityte Source Type: news

Utilizing ontologies and structural conceptual models for safety data management in aviation maintenance, repair and overhaul organizations - Kraus J, Lali š A, Plos V, Vittek P, Stojić S.
This paper deals with utilization of ontologies and conceptual structural models for improving safety data management in civil aviation maintenance, repair and overhaul organizations. It provides an overview of existing safety data management and identifie... (Source: SafetyLit)
Source: SafetyLit - December 31, 2018 Category: International Medicine & Public Health Tags: Research Methods, Surveillance and Codes, Models Source Type: news

5 Ways to boost brain health
(Natural News) If you’re scared that your brain is continually declining as the years go by, you can stop worrying. Contrary to popular belief, there are several ways to boost brain health and even repair damage. Scientific data has also proven that certain simple practices can help keep your brain “sharp and elastic” for the... (Source: NaturalNews.com)
Source: NaturalNews.com - December 28, 2018 Category: Consumer Health News Source Type: news

Latest Boston Sci Deal Shakes up Mitral Repair Market
Boston Scientific is slipping in one more deal (maybe?) before 2018 ends, and it could have significant implications. This time out, the Marlborough, MA-based company will gain a stronger foothold in the transcatheter mitral repair and replacement market by exercising its option to acquire the remaining shares of Millipede Inc. The deal will have Boston Scientific doling out $325 million with a $125 million payment becoming available upon achievement of a commercial milestone. The Millipede acquisition is set to close prior to the end of 1Q19. Boston Scientific’s latest acquisition target is developing th...
Source: MDDI - December 27, 2018 Category: Medical Devices Authors: Omar Ford Tags: Cardiovascular Business Source Type: news

Boston Scientific Exercises Option to Acquire Millipede, Inc.
Acquisition will expand structural heart portfolio to include transcatheter mitral annuloplasty repair system MARLBOROUGH, Mass., Dec. 27, 2018 -- (Healthcare Sales & Marketing Network) -- Boston Scientific Corporation (NYSE: BSX) today announced it ex... Devices, Interventional, Cardiology, Mergers & Acquisitions Boston Scientific, Millipede, Transcatheter, Annuloplasty, mitral regurgitation (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - December 27, 2018 Category: Pharmaceuticals Source Type: news

Boston Scientific acquires Millipede for $325m
Boston Scientific (NYSE:BSX) said today that it acquired Iris transcatheter annuloplasty ring developer Millipede in a deal worth approximately $325 million with the opportunity for an additional $125 million based on a commercial milestone. Santa Rosa, Calif.-based Millipede makes the Iris transcatheter annuloplasty ring for treating mitral valve regurgitation. Marlborough, Mass.-based Boston Scientific initially invested $90 million into Millipede in January, with an option to acquire the remaining shares in the company for $325 million and an additional $125 million milestone payment. Boston Scientific said th...
Source: Mass Device - December 27, 2018 Category: Medical Devices Authors: Fink Densford Tags: Business/Financial News Cardiovascular Featured Mergers & Acquisitions Wall Street Beat Boston Scientific millipede Source Type: news

Excellent 25-Year Survival After Tetralogy of Fallot Correction Excellent 25-Year Survival After Tetralogy of Fallot Correction
Long-term survival in a large cohort of young patients who had surgery to repair tetralogy of Fallot shows that the vast majority have survived without transplant.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - December 24, 2018 Category: Consumer Health News Tags: Cardiology News Source Type: news

Report: Despite settlement, patient seeks prosecution for off-label Seri scaffold breast surgery
A patient in Southern California who underwent breast reconstruction surgery using an off-label Seri surgical scaffold is pushing for the state to prosecute the operating plastic surgeon, despite having received $1 million in a settlement, over claims that he altered her medical records, according to a Pasadena Star News report. The patient, Wendy Knecht, underwent breast reconstruction in 2015 following a cancer-preventive double mastectomy procedure. She was treated by Dr. Max Lehfeldt, who used a Seri surgical scaffold, produced by Allergan (NYSE:AGN) at the time, despite the scaffold having no FDA indications for ...
Source: Mass Device - December 21, 2018 Category: Medical Devices Authors: Fink Densford Tags: Cosmetic/Aesthetic Legal News Women's Health Allergan Serica Technologies Sofregen Medical Source Type: news

Neurons from stem cells may stop seizures, improve cognitive function
Stem cells could be the cure for seizures and repair cognitive function in the brain for some patients, new research says. (Source: Health News - UPI.com)
Source: Health News - UPI.com - December 20, 2018 Category: Consumer Health News Source Type: news

Nerve repair dev Neuraptive Therapeutics raises $12m in Series A
Neuraptive Therapeutics said yesterday that it raised $11.5 million in a Series A round of equity financing to support its flagship AxoFuse nerve repair system through clinical trials and to expand operations. The round was led by private equity firm New Rhein Healthcare Investors, the Lafayette, Colo.-based company said. The AxoFuse system is a novel therapeutic product intended for use in standard nerve repair surgery to improve outcomes for patients with peripheral nerve injuries, the company said. Neuraptive said that preclinical studies of the device indicate that it can reduce recovery time and improve stable recover...
Source: Mass Device - December 20, 2018 Category: Medical Devices Authors: Fink Densford Tags: Business/Financial News Neurological neuraptivetherapeutics Source Type: news

Diabetes drug may also treat common heart failure syndrome, study says
A drug commonly used to treat type 2 diabetes could also help repair heart failure, a study says. (Source: Health News - UPI.com)
Source: Health News - UPI.com - December 19, 2018 Category: Consumer Health News Source Type: news

Medical News Today: Multiple sclerosis: Could this be why myelin fails to regenerate?
A study finds a previously unknown mechanism that quietens adult stem cells and could be a disruptor of myelin repair in inflammatory diseases, such as MS. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - December 19, 2018 Category: Consumer Health News Tags: Multiple Sclerosis Source Type: news

Smith & Nephew to pay up to $105m for Ceterix Orthopaedics
Smith & Nephew (NYSE:SNN) today announces that it has agreed to acquire Ceterix Orthopaedics and its NovoStitch Pro knee repair device. The deal calls for the British orthopedics and wound care giant to put up $50 million in up-front cash, with another $55 million due over the next five years, pegged to financial performance. Fremont, Calif.-based Ceterix’s NovoStitch Pro is designed to repair complex meniscal tears in the knee. Smith & Nephew said the device is “highly complementary” to its own Fast-Fix 360 device for vertical meniscal tears. “NovoStitch Pro is an outstanding technolog...
Source: Mass Device - December 18, 2018 Category: Medical Devices Authors: Brad Perriello Tags: Featured Mergers & Acquisitions Orthopedics Wall Street Beat Ceterix Orthopaedics Smith & Nephew Source Type: news

Life-size 3D-printed 'human' primed for radiation therapy
Researchers from Louisiana have created a 3D-printed full-body phantom that...Read more on AuntMinnie.comRelated Reading: 3D printing technique improves heart valve sizing 3D printing gives pediatric heart surgery a boost 3D-printed lungs improve patient understanding of surgery 3D head models reduce workload for brain radiotherapy 3D printing enhances training for cleft lip repair (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - December 18, 2018 Category: Radiology Source Type: news

Aortica touts FDA clearance to use Medtronic ’ s Valiant Navion in AAA IDE study
Aortica said today that the FDA approved the use of Medtronic‘s (NYSE:MDT) Valiant Navion stent graft system alongside Aortica’s AortaFit in a physician sponsored IDE study. The study, being run by principal investigator Dr. Benjamin Starnes at the University of Washington, will now use the Valiant Navion as a platform for fenestrated endovascular repair together with the AortaFit automated case planning software. “I am excited to bring Medtronic’s Navion into this study. The device architecture incorporates many of the features we feel are important to simplifying fenestrated EVAR and addressi...
Source: Mass Device - December 17, 2018 Category: Medical Devices Authors: Fink Densford Tags: Clinical Trials Food & Drug Administration (FDA) Vascular Aortica Medtronic Source Type: news

Outcomes and return to sport after pectoralis major tendon repair: a systematic review - Yu J, Zhang C, Horner N, Ayeni OR, Leroux T, Alolabi B, Khan M.
CONTEXT:: Pectoralis major tendon ruptures are becoming increasingly common due to the growing prevalence of active lifestyles. Studies investigating the efficacy of pectoralis major tendon repair have limited sample sizes and offer mixed results, while ex... (Source: SafetyLit)
Source: SafetyLit - December 16, 2018 Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news

Professional soccer players' return to play and performance after operative repair of achilles tendon rupture - Trofa DP, Noback PC, Caldwell JE, Miller JC, Greisberg JK, Ahmad CS, Vosseller JT.
BACKGROUND: The majority of Achilles tendon ruptures are sports related; however, no investigation has examined the impact of surgical repair for complete ruptures on professional soccer players. PURPOSE: To examine the return to play, playing time... (Source: SafetyLit)
Source: SafetyLit - December 15, 2018 Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news

In Anterior Cruciate Reconstruction, Meniscal Repair More Cost Effective Than Partial Meniscectomy
No abstract available (Source: Lippincott's Bone and Joint Newsletter)
Source: Lippincott's Bone and Joint Newsletter - December 15, 2018 Category: Orthopaedics Tags: Snapshot Source Type: news