Kidney cancer may begin developing in childhood years before disease diagnosis
SEEDS of kidney cancer may be planted in childhood or adolescence, decades before the disease is diagnosed, scientists have learned. The common fault, caused by the botched repair of broken chromosomes, remains hidden and harmless in the majority of the population. (Source: Daily Express - Health)
Source: Daily Express - Health - April 12, 2018 Category: Consumer Health News Source Type: news

CollPlant Appoints Revital Mandil-Levin as Chief Business Development Officer
NESS ZIONA, Israel, April 12, 2018 -- (Healthcare Sales & Marketing Network) -- CollPlant (NASDAQ: CLGN) (TASE: CLGN), a regenerative medicine company utilizing its proprietary plant-based rhCollagen technology for tissue repair products (recombinant hum... Regenerative Medicine, Personnel CollPlant, rhCollagen, Vergenix, VergenixSTR (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - April 12, 2018 Category: Pharmaceuticals Source Type: news

Conventus Orthopaedics Appoints Jonathan Isenburg as Chief Financial Officer
MINNEAPOLIS, April 12, 2018 -- (Healthcare Sales & Marketing Network) -- Conventus Orthopaedics, a medical device company revolutionizing fracture repair surgery, today announced the appointment of Jonathan Isenburg as its new Chief Financial Officer. Mr... Devices, Orthopaedic, Personnel Conventus Orthopaedics (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - April 12, 2018 Category: Pharmaceuticals Source Type: news

How Do You Know if Protein is ‘Complete’ or ‘Incomplete’?
This article originally appeared on Health.com (Source: TIME: Health)
Source: TIME: Health - April 12, 2018 Category: Consumer Health News Authors: Cynthia Sass / Health.com Tags: Uncategorized Diet/Nutrition healthytime onetime Source Type: news

Lung stem cells repair airways after injury
(University of Iowa Health Care) Working in mice, University of Iowa researchers have identified a new population of lung stem cells that appear to be important for regenerating the airway following severe injury. The cells, known as glandular myoepithelial cells (MECs), can self-renew and differentiate into seven distinct cell types in the airway. Overexpression of the transcription factor Lef-1 in MECs is sufficient to activate the cells' regenerative response even in the absence of airway injury. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - April 12, 2018 Category: International Medicine & Public Health Source Type: news

You Asked: What Is Inflammation, And Why Should I Care About It?
Your body can heal itself, which is pretty miraculous when you sit back and think about it. If you suffer a cut or infection—or if a disease, allergen or virus finds its way into you—your immune system reacts by sending specialized white blood cells to the affected area. These white blood cells can repair damage, stop the spread of infection or illness and in some cases eradicate the intruder. This whole response is called inflammation. “Inflammation is an activation of cells and cell-derived components that have the job of fighting invasions, and in some cases just sponging up or clearing out damaged cel...
Source: TIME: Health - April 11, 2018 Category: Consumer Health News Authors: Markham Heid Tags: Uncategorized healthytime medicine Source Type: news

This 3-year-old has ‘ a sparkle ’ in her heart: The world ’ s smallest mechanical heart valve
When Sadie Rutenberg was born, she had a gaping hole between the two sides of her heart, and her heart valves were malformed and leaking. In her first few months of life, she had already undergone two open-heart surgeries; but the damage was too extensive to repair, and the blond-haired, blue-eyed infant was failing to thrive. Her parents said there […]Related:FDA restricts sale of Essure contraceptive device, requires that women be informed of risksWith $2 million, Kaiser Permanente wants to help revive underfunded gun-violence researchThe CDC researcher who mysteriously vanished in Februar...
Source: Washington Post: To Your Health - April 11, 2018 Category: Consumer Health News Source Type: news

HeartStitch touts tricuspid repair feasibility cases
Structural heart focused medtech company HeartStitch said today that its HeartStitch Remo Pro suture technique was used in a world first procedure to repair the tricuspid valve of two patients as part of a feasibility trial of the technique and the supporting technology. The procedures were performed by Dr. Yuri Pya at Astana, Kazakhstan’s National Research Cardiac Surgery Center, the company said. Both patients in the trial required tricuspid heart valve repair to remodel the annulus of their tricuspid valve to treat tricuspid regurgitation. Patients in the feasibility test tolerated the procedure and have been...
Source: Mass Device - April 10, 2018 Category: Medical Devices Authors: Fink Densford Tags: Cardiovascular Clinical Trials HeartStitch Source Type: news

In-depth analysis of pattern of occupational injuries and utilization of safety measures among workers of railway wagon repair workshop in Jhansi (U.P.) - Gupta S, Malhotra AK, Verma SK, Yadav R.
CONTEXT: Occupational injuries constitute a global health challenge, yet they receive comparatively modest scientific attention. Pattern of occupational injuries and its safety precautions among wagon repair workers is an important health issue, especially... (Source: SafetyLit)
Source: SafetyLit - April 10, 2018 Category: International Medicine & Public Health Tags: Occupational Issues Source Type: news

RegeneRx Announces Outcome of FDA Discussions for Development of RGN-259 for Dry Eye Syndrome
ROCKVILLE, Md., April 9, 2018 -- (Healthcare Sales & Marketing Network) -- RegeneRx Biopharmaceuticals, Inc. (OTCQB: RGRX) ("the Company" or "RegeneRx"), a clinical-stage drug development company focused on tissue protection, repair an... Biopharmaceuticals, Ophthalmology, FDA RegeneRx Biopharmaceuticals, ReGenTree, Dry Eye (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - April 9, 2018 Category: Pharmaceuticals Source Type: news

How Do You Fix A Broken Nail?
Discussion Distal digits, especially of the hand, are important as they provide support for pinching and grip, give tactile sensation and contribute to cosmesis. Trauma to the distal digit and nailbed ranges from significant trauma with digital crush injuries or amputation to minor broken nails causing only annoyance. Most injuries especially in children involve the hand especially the middle finger. The dominant hand is more common if the child has a hand-preference. Usually they occur indoors especially being caused by being pinched by a door. Significant trauma requires surgical intervention and may require specialty s...
Source: PediatricEducation.org - April 9, 2018 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

'Sleeping' stem cells could aid brain repair
(University of Cambridge) Scientists at the Wellcome Trust/ Cancer Research UK Gurdon Institute, University of Cambridge, have identified a new type of stem cell in the brain which they say has a high potential for repair following brain injury or disease. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - April 5, 2018 Category: International Medicine & Public Health Source Type: news

This retinal implant may one day cure blindness caused by macular degeneration
For many of the 10 million Americans who are losing their vision to a thievish eye condition with no treatment, help may be on its way.In a very early clinical trial, researchers have implanted a stem cell “patch” to repair failing retinal cells in four patients with a condition called “dry” macular... (Source: Los Angeles Times - Science)
Source: Los Angeles Times - Science - April 5, 2018 Category: Science Authors: Melissa Healy Source Type: news

ESCRTs offer repair service
(Source: ScienceNOW)
Source: ScienceNOW - April 5, 2018 Category: Science Authors: Gutierrez, M. G., Carlton, J. G. Tags: Cell Biology perspective Source Type: news

Cell cycle heterogeneity directs the timing of neural stem cell activation from quiescence
In this study, however, we demonstrate that quiescent NSCs (qNSCs) are arrested in either G2 or G0. G2-G0 heterogeneity directs NSC behavior: G2 qNSCs reactivate before G0 qNSCs. In addition, we show that the evolutionarily conserved pseudokinase Tribbles (Trbl) induces G2 NSCs to enter quiescence by promoting degradation of Cdc25String and that it subsequently maintains quiescence by inhibiting Akt activation. Insulin signaling overrides repression of Akt and silences trbl transcription, allowing NSCs to exit quiescence. Our results have implications for identifying and manipulating quiescent stem cells for regenerative p...
Source: ScienceNOW - April 5, 2018 Category: Science Authors: Otsuki, L., Brand, A. H. Tags: Development, Neuroscience reports Source Type: news

Triggered recruitment of ESCRT machinery promotes endolysosomal repair
Endolysosomes can be damaged by diverse materials. Terminally damaged compartments are degraded by lysophagy, but pathways that repair salvageable organelles are poorly understood. Here we found that the endosomal sorting complex required for transport (ESCRT) machinery, known to mediate budding and fission on endolysosomes, also plays an essential role in their repair. ESCRTs were rapidly recruited to acutely injured endolysosomes through a pathway requiring calcium and ESCRT-activating factors that was independent of lysophagy. We used live-cell imaging to demonstrate that ESCRTs responded to small perforations in endoly...
Source: ScienceNOW - April 5, 2018 Category: Science Authors: Skowyra, M. L., Schlesinger, P. H., Naismith, T. V., Hanson, P. I. Tags: Cell Biology, Online Only r-articles Source Type: news

New Stem Cell Treatment Could Help People Suffering From ALS
BOSTON (CBS) – Massachusetts General Hospital is testing a new treatment that could help people suffering with ALS. Forty-one-year-old David Neufeglise was a healthy family man and mechanical engineer when he started noticing constant twitching in his arm. After months of tests, the devastating diagnosis came back last January as ALS. “Hearing a doctor say it…uh, it takes your breath away,” says David. “You think about all your hopes and dreams for the future and your family, and your career, and everything. And it puts all those into question.” David Neufeglise (WBZ-TV) Life suddenly ...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - April 4, 2018 Category: Consumer Health News Authors: Health – CBS Boston Tags: Health Local News Syndicated Local ALS Dr. Mallika Marshall stem cell treatment Source Type: news

A pop-up repair shop for damaged neurons
Collaborative research holds promise for harnessing the nervous system ’s own repair programs to develop therapies for neurodegeneration and traumatic brain injury. (Source: UCSF School of Pharmacy News)
Source: UCSF School of Pharmacy News - April 4, 2018 Category: Universities & Medical Training Authors: Paula Joyce Source Type: news

Medical News Today: Space travel may hold the key to cardiac repair
New research — conducted both in space and on Earth — suggests that simulated microgravity could be used to boost stem-cell therapy for cardiac repair. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - April 4, 2018 Category: Consumer Health News Tags: Stem Cell Research Source Type: news

Gore wins expanded indications for Cardioform septal occluder
W.L. Gore & Associates said today it won expanded FDA indications for its Cardioform septal occluder, now cleared for the closure of patent foramen ovale to reduce the risk of recurrent ischemic stroke in certain patients. The expanded application was supported by results from the Reduce study, which the Newark, Del.-based company said showed that closure of PFOs could significantly prevent recurrent ischemic stroke regardless of PFO anatomy. “With the FDA approval of the Gore Cardioform septal occluder for PFO closure, we can now provide physicians with one device that can be used for both ASDs and PFOs. The val...
Source: Mass Device - April 3, 2018 Category: Medical Devices Authors: Fink Densford Tags: Cardiovascular Food & Drug Administration (FDA) Regulatory/Compliance W.L. Gore & Associates Source Type: news

Early Alcohol Use in Pregnancy Tied to Gastroschisis
TUESDAY, April 3, 2018 -- Alcohol consumption early in pregnancy may be a risk factor for the development of gastroschisis in neonates, according to a study published recently in the Journal of Maternal-Fetal& Neonatal Medicine. Jean R.... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - April 3, 2018 Category: Pharmaceuticals Source Type: news

The nociceptin receptor inhibits axonal regeneration and recovery from spinal cord injury
Axonal growth after traumatic spinal cord injury is limited by endogenous inhibitors, selective blockade of which promotes partial neurological recovery. The partial repair phenotypes suggest that compensatory pathways limit improvement. Gene expression profiles of mice deficient in Ngr1, which encodes a receptor for myelin-associated inhibitors of axonal regeneration such as Nogo, revealed that trauma increased the mRNA expression of ORL1, which encodes the receptor for the opioid-related peptide nociceptin. Endogenous and overexpressed ORL1 coimmunoprecipitated with immature NgR1 protein, and ORL1 enhanced the O-linked g...
Source: Signal Transduction Knowledge Environment - April 3, 2018 Category: Science Authors: Sekine, Y., Siegel, C. S., Sekine-Konno, T., Cafferty, W. B. J., Strittmatter, S. M. Tags: STKE Research Articles Source Type: news

Spaceflight activates cell changes   with implications for stem cell-based heart repair
(Mary Ann Liebert, Inc./Genetic Engineering News) A new study of the effects of spaceflight on the development of heart cells identified changes in calcium signaling that could be used to develop stem cell-based therapies for cardiac repair. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - April 2, 2018 Category: International Medicine & Public Health Source Type: news

Medical News Today: What to know about hiatal hernia surgery
Surgery is an effective way to treat a hiatal hernia, with a 90 –95 percent success rate in relieving symptoms such as acid reflux and GERD. Laparoscopic repair is the most common procedure. Recovery takes several weeks but a person can often go home the same day. Learn about recovery times, complications, and outlook. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - March 31, 2018 Category: Consumer Health News Tags: Surgery Source Type: news

Wright launches Invision ankle revision, Prophecy preoperative nav systems in US
Wright Medical (NSDQ:WMGI) last week announced the US launch of its Invision total ankle revision system and Prophecy preoperative navigation planning system. The Memphis, Tenn.-based company touted the Prophecy preoperative navigation system as the first such system with patient specific instrumentation designed for ankle revision arthroplasty procedures. “Revision of a failed total ankle arthroplasty remains a challenge. The ability to preoperatively plan out these cases and determine appropriate alignment based on the individual patient’s CT data will provide surgeons with an extra level of confidence t...
Source: Mass Device - March 28, 2018 Category: Medical Devices Authors: Fink Densford Tags: Blood Management Orthopedics wrightmedical Source Type: news

Intact Vascular Has a Unique Way to Treat PAD Patients
Intact Vascular is hoping to have a below-the-knee (BTK) indication for its Tack Endovascular System in 2020 company executives, told MD+DI. Data from the Tack Optimized Balloon Angioplasty Below the Knee (TOBA BTK) clinical trial, an initial study of the technology, was published in the current issue of Catheterization and Cardiovascular Intervention. The published data could help pave the way for an approval.  The Tack Endovascular System is an implant for the precision dissection repair following balloon angioplasty and received CE mark in 2012. The device is designed to help maintain vessel integrity and impr...
Source: MDDI - March 27, 2018 Category: Medical Devices Authors: Omar Ford Tags: Cardiovascular Business Source Type: news

Scientists Have Discovered a New Organ in the Human Body
It’s not a second stomach or a mini-brain. But scientists have discovered an important new organ that may play a critical role in how many tissues and other organs do their jobs, as well as in some diseases like cancer. In a study published in Scientific Reports, a New York University-led team of researchers describe the interstitium, which is a series of connected, fluid-filled spaces found under skin as well as throughout the gut, lungs, blood vessels and muscles. The bubble wrap-like network only became visible when the pathologists used a new laser endoscope, called a confocal laser endomicroscope, that allowed ...
Source: TIME: Health - March 27, 2018 Category: Consumer Health News Authors: Alice Park Tags: Uncategorized health healthytime medicine Source Type: news

Scientists Have Discovered a New Organ in the Human Body. What is the Interstitium?
It’s not a second stomach or a mini-brain. But scientists have discovered an important new organ that may play a critical role in how many tissues and other organs do their jobs, as well as in some diseases like cancer. In a study published in Scientific Reports, a New York University-led team of researchers describe the interstitium, which is a series of connected, fluid-filled spaces found under skin as well as throughout the gut, lungs, blood vessels and muscles. The bubble wrap-like network only became visible when the pathologists used a new laser endoscope, called a confocal laser endomicroscope, that allowed ...
Source: TIME: Health - March 27, 2018 Category: Consumer Health News Authors: Alice Park Tags: Uncategorized health healthytime medicine Source Type: news

Second Sight Medical taps Blake as CFO | Personnel Moves – March 27, 2018
Second Sight Medical (NSDQ:EYES) said last week it named John Blake as its new chief financial officer, succeeding Thomas Miller who has held the position since 2014. Before joining Second Sight Medical, Blake acted as finance senior VP at Tyr Pharma, and has held positions with Volcano Corp and BD Biosciences, the company said. Blake worked with Volcano during its $1.2 billion sale to Royal Philips (NYSE:PHG) in 2015, Second Sight added. “We are delighted to welcome John to the Second Sight team. John’s financial acumen, track record of results and broad life sciences industry experience wi...
Source: Mass Device - March 27, 2018 Category: Medical Devices Authors: Fink Densford Tags: Business/Financial News acessahealth Bayer Boston Scientific collagenmatrix Dentsply Sirona innovatusimaging integralifesciences NovaBone Nuvasive Orthovita Inc. Paradigm Spine royalphilips Second Sight Smith & Nephew Trice M Source Type: news

New connections: Healed by ROS
ROS generated by Nox2 or mitochondria play critical roles in mammalian tissue repair pathways. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - March 27, 2018 Category: Science Authors: Wong, W. Tags: STKE Editors ' Choice Source Type: news

Preventing Interpersonal Violence in Relationships, Part 1
As a therapist, I want to help survivors of dating violence, domestic violence, and abusive relationships recover their sense of safety and self-fulfillment in life. And I want to do more. I want more people to know how grave the damage is to survivors of abuse and sexual assault. I want to see more action and education to stop dating and interpersonal violence and prevent it. Artists and performers can be powerful allies for awareness. In a song “The Whole Damn Year,” singer songwriter Mary J. Blige explains the harrowing experience of a person living with relationship trauma: Bad, how deep the pain is Oh, you...
Source: Psych Central - March 25, 2018 Category: Psychiatry Authors: Robyn Brickel, MA, LMFT Tags: Abuse Anger Codependence PTSD Relationships & Love Trauma Women's Issues #metoo controlling behavior dating abuse dating violence Domestic Violence Emotional Abuse Insecurity Intimate Partner Abuse intimidation Jealousy R Source Type: news

Yoga can increase blood flow, aiding in repair and regeneration of tissue
(Natural News) Research has found out that yoga improves the way our organs function. In particular, yoga stimulates bone marrow stem cells trafficking to the blood surrounding it. This, in turn, helps reduce inflammation, reduce apoptosis, revive lost cells and delay the aging process. The results of this study were published in the Journal of Ayurveda and... (Source: NaturalNews.com)
Source: NaturalNews.com - March 25, 2018 Category: Consumer Health News Source Type: news

SafeHeal raises $7m
Early stage medtech dev SafeHeal said today it has raised $7.4 million (EU €6 million) in a Series A round of financing, with funds slated to support the clinical and regulatory market access and a commercial launch. The Paris-based company is developing the Colovac, a digestive anastomosis protection device designed to reduce complications and remove the need for ostomies in colectomy patients. The system consists of a minimally invasive, full reversible implant that remains in place for approximately two weeks, or until tissue repair is complete, before removal. “This investment enables us to execute our aggre...
Source: Mass Device - March 23, 2018 Category: Medical Devices Authors: Fink Densford Tags: Business/Financial News safeheal Source Type: news

Military surgeons report 'alarming frequency' of bench press injuries
(Loyola University Health System) A new study has found that serious chest muscle injuries are occurring with 'alarming frequency' among deployed service members who lift weights. The injuries -- tears of the pectoralis major tendon -- occurred while doing bench press weight training. The injuries then required surgical repair and six months recovery. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 22, 2018 Category: International Medicine & Public Health Source Type: news

Sexual Function Better With Laparoscopic Mesh After Cystocele Repair Sexual Function Better With Laparoscopic Mesh After Cystocele Repair
For cystocele repair, laparoscopic mesh sacropexy (LS) is safer and better preserves sexual function than does transvaginal mesh repair (TVM), according to a randomized trial from France.Reuters Health Information (Source: Medscape General Surgery Headlines)
Source: Medscape General Surgery Headlines - March 21, 2018 Category: Surgery Tags: Ob/Gyn & Women ' s Health News Source Type: news

Effect of acupuncture on the TLR2/4-NF- κB signalling pathway in a rat model of traumatic brain injury - Lin SJ, Cao LX, Cheng SB, Dai QF, Lin JH, Pu L, Chen WH, Zhang YJ, Chen SL, Zhang YM.
OBJECTIVE: To study the effect of acupuncture on the TLR2/4-NF- κB signalling pathway in the cortex of Sprague-Dawley rats following traumatic brain injury (TBI), and investigate the possible mechanism underlying the effects of acupuncture on scar repair. ... (Source: SafetyLit)
Source: SafetyLit - March 21, 2018 Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news

Eye drops that can repair corneas could make glasses obsolete
(Natural News) For individuals with eyesight problems, eyeglasses can be a godsend. But many people who use eyeglasses also find them to be problematic sometimes. That’s why alternatives have been invented: So that options exist for those who don’t want to wear eyeglasses to solve their eyesight problems. Now, ophthalmologists from the Shaare Zedek Medical... (Source: NaturalNews.com)
Source: NaturalNews.com - March 21, 2018 Category: Consumer Health News Source Type: news

BD Scores a Victory in Bard & #039;s Hernia Mesh Case
Becton Dickinson, which acquired C.R. Bard at the end of 2017, scored a victory in New Jersey Superior Court this week. The court's appellate division refused to reinstate a product liability lawsuit involving Bard's 3DMax polypropylene mesh, which is used for hernia repair.  Plaintiff Kemuel Goodson was implanted with the product in 2006 and alleged that the mesh caused multiple complications that required extensive medical care, including several additional operations. Goodson claimed in his original complaint that defective design, negligence, and fraud and misrepresentation were to blame for the com...
Source: MDDI - March 21, 2018 Category: Medical Devices Authors: Amanda Pedersen Tags: Business Design Source Type: news

Bard wins 3DMax hernia mesh appeal
The New Jersey Superior Court’s Appellate Division this week tossed a win to Becton Dickinson & Co.‘s (NYSE:BDX) C.R. Bard (NYSE:BCR), refusing to reinstate a hernia mesh product liability suit on grounds that expert witnesses couldn’t prove the design of the product was defective or that significant negligence occurred. In the case, plaintiff Kemuel Goodson claims that implantation of Bard’s 3DMax polypropylene mesh during a laparoscopic bilateral inguinal hernia repair in 2006 caused a number of different complications, including remaining pain and the removal of a testicle, and requ...
Source: Mass Device - March 20, 2018 Category: Medical Devices Authors: Fink Densford Tags: Legal News Surgical bectondickinson crbard Source Type: news

Things Are Finally Looking Up for Endologix
Endologix has had a rough couple of years, but things are finally beginning to look up for the Irvine, CA-based company. Earlier this month the company enrolled the first patient in a confirmatory study of its next-generation Nellix endovascular aneurysm sealing system, an important step toward eventually getting that technology to the U.S. market. The good news continues this week with positive results from a pooled analysis of studies evaluating the company's Ovation product line. Ovation, a next-generation endovascular aneurysm repair (EVAR) system that uses polymer to help physicians create a customized seal between th...
Source: MDDI - March 20, 2018 Category: Medical Devices Authors: Amanda Pedersen Tags: Business Source Type: news

Wright Medical, KFx settle patent spat, ink licensing deal
KFx Medical said today it and Wright Medical (NSDQ:WMGI) agreed to dismiss patent litigation over rotator cuff repair patents between the companies and ink a licensing deal. Through the newly inked deal, Memphis, Tenn.-based Wright Medical and its affiliates will have the right to promote the use of products and techniques for knotless double row rotator cuff repair, which KFx owns the patent for, for the life of those patents. Terms of the deal were not disclosed. “We are proud to have our innovation recognized by Wright. Previously we announced our licensing agreements with Smith & Nephew, Inc., Mitek...
Source: Mass Device - March 19, 2018 Category: Medical Devices Authors: Fink Densford Tags: Business/Financial News Orthopedics Patent Infringement KFx Medical wrightmedical Source Type: news

Abbott's MitraClip Therapy Receives National Reimbursement in Japan to Treat Patients with Mitral Regurgitation
National reimbursement adds the device into Japan's health insurance system, which enables greater access for patients MitraClip is a first-of-its-kind transcatheter mitral valve repair device that provides physicians with a minimally invasive way to re... Devices, Cardiology, Reimbursement Abbott, MitraClip, mitral regurgitation, mitral valve (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - March 19, 2018 Category: Pharmaceuticals Source Type: news

Baxter closes $153m hemostat, sealant asset buy from Mallinckrodt
Baxter (NYSE:BAX) said today that it closed the $153 million acquisition of hemostat and sealant assets from Mallinckrodt Pharmaceuticals (NYSE:MNK). Baxter announced in January its plan to acquire the stand-alone recombinant thrombin Recothrom and Preveleak surgical sealant for vascular reconstruction. “We are excited to add both Recothrom and Preveleak to our portfolio of hemostats and sealants to offer surgeons additional options that address different situations when intraoperative bleeding can occur,” advanced surgery president Wil Boren said in prepared remarks. “Our top priority righ...
Source: Mass Device - March 19, 2018 Category: Medical Devices Authors: Brad Perriello Tags: Mergers & Acquisitions Surgical Vascular Wall Street Beat Baxter Mallinckrodt Source Type: news

HRD-positive breast cancer patients fare better with adjuvant AC chemotherapy
(SWOG) People with tough-to-treat triple negative breast cancer, whose tumors also don't allow for double-strand DNA repair, fare better when treated with a common adjuvant breast cancer chemotherapy combination, according to results from a SWOG clinical trial. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 19, 2018 Category: International Medicine & Public Health Source Type: news

10 Good and 10 Bad Things About Procrastination
“Don’t put off until tomorrow what you can do today.” – Benjamin Franklin “There’s nothing to match curling up with a good book when there’s a repair job to be done around the house.” – Joe Ryan Everyone procrastinates. Some, in fact, are proficient at it. While I used to count myself in that category, I’ve made a conscious effort to change my ways in recent years and I must say I’ve been quite successful in the endeavor. Still, the urge to put off what must be done occasionally plagues me. So, I found the research on what’s good and what’s bad a...
Source: Psych Central - March 18, 2018 Category: Psychiatry Authors: Suzanne Kane Tags: Anxiety General Habits Happiness Motivation and Inspiration Self-Help Habit Change overwhelm Procrastination Source Type: news

Scott Kelly Spent a Year in Space and Now His DNA Is Different From His Identical Twin ’s
Astronaut Scott Kelly, who spent a full year in space as part of a groundbreaking NASA mission, is no longer an exact genetic match with his identical twin brother Mark Kelly, according to a new study. Scientists found that Scott Kelly, who set the record for most consecutive days spent in orbit, underwent an “unexpected” genetic change. Post-flight, NASA investigators found “hundreds of unique mutations.” Some involved the circulation of so-called cell-free DNA in the blood. Others involved changes in the epigenome — a sort of genetic control system that determines how genes are expressed. St...
Source: TIME: Science - March 15, 2018 Category: Science Authors: Flora Carr Tags: Uncategorized onetime space travel Source Type: news

Startup promises minimally invasive heart repair
(Harvard University) A minimally invasive surgical device to be commercialized by a newly launched startup could fundamentally transform the way doctors correct organ defects. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 15, 2018 Category: International Medicine & Public Health Source Type: news

Does our body clock hold the key to developing new treatments?
Most of us will have felt the temporary effects of a disrupted body clock, whether it’s caused by a long flight, a changing shift pattern or even just a few late nights. Butscientists all over the world now recognise the importance of our biological clocks to lifelong health and well-being.In 2014 Arthritis Research UK invested more than a million pounds into two five-year studies at the University of Manchester investigating how disruption to our daily circadian rhythms is linked to osteoarthritis and inflammatory arthritis. In this edition we’re reporting on how this exciting new research is building our unde...
Source: Arthritis Research UK - March 15, 2018 Category: Rheumatology Source Type: news

Mutation dynamics and fitness effects followed in single cells
Mutations have been investigated for more than a century but remain difficult to observe directly in single cells, which limits the characterization of their dynamics and fitness effects. By combining microfluidics, time-lapse imaging, and a fluorescent tag of the mismatch repair system in Escherichia coli, we visualized the emergence of mutations in single cells, revealing Poissonian dynamics. Concomitantly, we tracked the growth and life span of single cells, accumulating ~20,000 mutations genome-wide over hundreds of generations. This analysis revealed that 1% of mutations were lethal; nonlethal mutations displayed a he...
Source: ScienceNOW - March 15, 2018 Category: Science Authors: Robert, L., Ollion, J., Robert, J., Song, X., Matic, I., Elez, M. Tags: Evolution, Microbiology reports Source Type: news

Does our body clock hold the key to developing new treatments for arthritis?
Most of us will have felt the temporary effects of a disrupted body clock, whether it’s caused by a long flight, a changing shift pattern or even just a few late nights. Butscientists all over the world now recognise the importance of our biological clocks to lifelong health and well-being.In 2014 Arthritis Research UK invested more than a million pounds into two five-year studies at the University of Manchester investigating how disruption to our daily circadian rhythms is linked to osteoarthritis and inflammatory arthritis. In this edition we’re reporting on how this exciting new research is building our unde...
Source: Arthritis Research UK - March 15, 2018 Category: Rheumatology Source Type: news