OHSU scientist on his 'CRISPR' technology to repair genetic mutation in human embryos
OHSU scientists confirmed a report leaked last week that they used a gene-editing technique to correct a mutation in a human embryo and prevent it from being passed to future generations. Using the gene-editing tool CRISPR, they targeted a mutation in nuclear DNA that causes a common genetic heart disease that can lead to sudden cardiac death and heart failure. “We have to find the mutant gene and correct it,” said Shoukhrat Mitalipov, who directs the Center for Embryonic Cell and Gene Therapy… (Source: bizjournals.com Health Care:Physician Practices headlines)
Source: bizjournals.com Health Care:Physician Practices headlines - August 2, 2017 Category: American Health Authors: Elizabeth Hayes Source Type: news

Geneticists Repair Mutation in Human Embryo
WEDNESDAY, Aug. 2, 2017 -- In a first-ever experiment, geneticists have successfully modified a human embryo to remove a mutation that causes a life-threatening heart condition. This is the first study to demonstrate that a gene-editing technique... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - August 2, 2017 Category: General Medicine Source Type: news

Early gene-editing success holds promise for preventing inherited diseases
(Salk Institute) Scientists achieve first safe repair of single-gene mutation in human embryos. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 2, 2017 Category: International Medicine & Public Health Source Type: news

FDA OKs Nivolumab in Metastatic Colorectal Cancer FDA OKs Nivolumab in Metastatic Colorectal Cancer
The FDA has given accelerated approval to nivolumab for the treatment of microsatellite instability-high or mismatch repair deficient metastatic colorectal cancer.FDA Approvals (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - August 1, 2017 Category: Consumer Health News Tags: Hematology-Oncology News Alert Source Type: news

FDA OKs Nivolumab in Metastatic CRC Subtype FDA OKs Nivolumab in Metastatic CRC Subtype
The FDA has given accelerated approval to nivolumab for the treatment of microsatellite instability-high or mismatch repair deficient metastatic colorectal cancer.FDA Approvals (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - August 1, 2017 Category: Cancer & Oncology Tags: Hematology-Oncology News Alert Source Type: news

Missing signals lead to diabetic nerve injury
(Case Western Reserve University) Molecules that help cells communicate with each other--called cytokines--might be the key to repairing diabetic nerve damage, according to a new study published in Experimental Neurology. Diabetes devastates nerve cells, which can lead to poor circulation, muscle weakness, blindness, and other painful side effects. The new study showed diabetic mice can't repair nerve cells after damage due to low levels of specific cytokines. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 1, 2017 Category: International Medicine & Public Health Source Type: news

News Analysis: How to Repair the Health Law (It ’ s Tricky but Not Impossible)
Stabilizing the market, lowering drug prices and expanding access to coverage would go a long way to easing millions of Americans ’ concerns. (Source: NYT Health)
Source: NYT Health - July 29, 2017 Category: Consumer Health News Authors: REED ABELSON, ABBY GOODNOUGH and KATIE THOMAS Tags: Health Insurance and Managed Care Patient Protection and Affordable Care Act (2010) Law and Legislation Drugs (Pharmaceuticals) Medicaid Republican Party Democratic Party United States Politics and Government Source Type: news

Republicans Try to Regroup After Health Care Failure; Democrats Exult
After loss, Democratic leaders urge Republicans to negotiate with them to repair the Affordable Care Act. (Source: NYT Health)
Source: NYT Health - July 28, 2017 Category: Consumer Health News Authors: MATT FLEGENHEIMER Tags: Politics and Government Health Insurance and Managed Care Schumer, Charles E Trump, Donald J Pelosi, Nancy Source Type: news

Stretchy glue inspired by slugs could be the future of sutures
  Inspired by slug slime, scientists have developed a flexible adhesive that sticks to wet surfaces. This stretchy glue can be attached to a beating, bleeding heart and could someday replace stitches in wound repair. Other commercially available glues create strong but inflexible bonds or stretchy but weak connections. The slug-inspired glue cements tightly and […]Related:New debate on antibiotics: Do you really need to take the full course?These experimental treatments target brain cancer like John McCain’sSperm concentration has declined 50 percent in 40 years in three continents (Source: Washington Post: To Your Health)
Source: Washington Post: To Your Health - July 27, 2017 Category: Consumer Health News Source Type: news

Researchers report regenerative effects of low-dose growth factors for bone defect healing
(Mary Ann Liebert, Inc./Genetic Engineering News) Researchers compared the effects of three bone growth factors to bone morphogenetic protein 2 (BMP2)--the most commonly used agent for repair of large bone defects, which is not without risks at the doses required -- and showed significant bone-healing effects including the formation of new blood vessels at low doses relative to BMP2. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 27, 2017 Category: International Medicine & Public Health Source Type: news

Errors made by 'DNA spellchecker' revealed as important cause of cancer
(Center for Genomic Regulation) CRG scientists identify important processes that create mutations that cause cancer by studying the genomes of more than 1,000 tumors. Many mutations in human cancers are caused by mistakes made by a repair mechanism or 'DNA spellchecker' rather than the actual damage to DNA caused by the environment. Sunlight and alcohol consumption increase the rate at which this happens, resulting in more mutations in the most important parts of our genomes. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - July 27, 2017 Category: Cancer & Oncology Source Type: news

Mismatch repair deficiency predicts response of solid tumors to PD-1 blockade
The genomes of cancers deficient in mismatch repair contain exceptionally high numbers of somatic mutations. In a proof-of-concept study, we previously showed that colorectal cancers with mismatch repair deficiency were sensitive to immune checkpoint blockade with antibodies to programmed death receptor–1 (PD-1). We have now expanded this study to evaluate the efficacy of PD-1 blockade in patients with advanced mismatch repair–deficient cancers across 12 different tumor types. Objective radiographic responses were observed in 53% of patients, and complete responses were achieved in 21% of patients. Responses we...
Source: ScienceNOW - July 27, 2017 Category: Science Authors: Le, D. T., Durham, J. N., Smith, K. N., Wang, H., Bartlett, B. R., Aulakh, L. K., Lu, S., Kemberling, H., Wilt, C., Luber, B. S., Wong, F., Azad, N. S., Rucki, A. A., Laheru, D., Donehower, R., Zaheer, A., Fisher, G. A., Crocenzi, T. S., Lee, J. J., Grete Tags: Medicine, Diseases reports Source Type: news

Tough adhesives for diverse wet surfaces
We report a bioinspired design for adhesives consisting of two layers: an adhesive surface and a dissipative matrix. The former adheres to the substrate by electrostatic interactions, covalent bonds, and physical interpenetration. The latter amplifies energy dissipation through hysteresis. The two layers synergistically lead to higher adhesion energies on wet surfaces as compared with those of existing adhesives. Adhesion occurs within minutes, independent of blood exposure and compatible with in vivo dynamic movements. This family of adhesives may be useful in many areas of application, including tissue adhesives, wound d...
Source: ScienceNOW - July 27, 2017 Category: Science Authors: Li, J., Celiz, A. D., Yang, J., Yang, Q., Wamala, I., Whyte, W., Seo, B. R., Vasilyev, N. V., Vlassak, J. J., Suo, Z., Mooney, D. J. Tags: Materials Science reports Source Type: news

Integra LifeSciences slides on Q2 results
Integra LifeSciences (NSDQ:IART) shares are under pressure this morning after the medical device maker reported its second-quarter results and lowered its outlook for the rest of the year. Plainsboro, N.J.-based Integra posted profits of $10.8 million, or 14¢ per share, on sales of $282.2 million for the three months ended June 30, for a bottom-line slide of -15.1% on sales growth of 13.2% compared with Q2 2016. Adjusted to exclude one-time items, earnings per share were 45$, dead even with the consensus on Wall Street, where analysts were looking for sales of $283.7 million. “Profitability and cash flows were s...
Source: Mass Device - July 26, 2017 Category: Medical Devices Authors: Brad Perriello Tags: MassDevice Earnings Roundup Orthopedics Surgical Wall Street Beat Integra LifeSciences Corp. Source Type: news

Biomarkers for identifying tumor aggressiveness
(Max Delbr ü ck Center for Molecular Medicine in the Helmholtz Association) Future early-stage colon cancer patients could benefit from specific genetic tests that forecast their prognosis and help them make the right decision regarding chemotherapy. Two of the biomarkers are the MACC1 gene, high levels of which promote aggressive tumor growth and the development of metastasis, and a defective DNA mismatch repair (dMMR) system, which plays a role in tumor formation. Life expectancy is longer for patients with dMMR tumors and with low MACC1 gene activity. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - July 26, 2017 Category: Cancer & Oncology Source Type: news

Stanford researchers engineer 3-D hydrogels for tissue-specific cartilage repair
(Mary Ann Liebert, Inc./Genetic Engineering News) Unlike the one-size-fits-all, homogeneous approach to tissue engineering for cartilage replacement, a new study reports the ability to encapsulate cartilage-forming chondrocytes and mesenchymal stem cells in 3-D hydrogels within a stiffness gradient. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - July 26, 2017 Category: Biology Source Type: news

New Surgery May Fix Tough-to-Treat Rotator Cuff Tears
TUESDAY, July 25, 2017 -- A new surgical procedure can help people with shoulder injuries once considered beyond repair, a small new study suggests. Out of 100 patients who had the surgery in the study, all 26 of those who had played sports before... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - July 25, 2017 Category: General Medicine Source Type: news

Zebrafish molecules could help repair damaged nerves
University of Edinburgh researchers say they have uncovered a 'vital mechanism' in the damaged spines of zebrafish that helps nerve connections to regrow (stock image) (Source: the Mail online | Health)
Source: the Mail online | Health - July 25, 2017 Category: Consumer Health News Source Type: news

Medical News Today: Chordee: Definition, surgery, and repair
Chordee is when the penis appears curved or bent. Learn about this condition, how it is diagnosed, and treatment options, including surgery. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - July 25, 2017 Category: Consumer Health News Tags: Men's Health Source Type: news

Zebrafish study reveals clues to healing spinal cord injuries
(University of Edinburgh) Fresh insights into how zebrafish repair their nerve connections could hold clues to new therapies for people with spinal cord injuries. Researchers at the University of Edinburgh have pinpointed key molecules that prompt damaged nerve fibres in the fish to regenerate themselves. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 25, 2017 Category: International Medicine & Public Health Source Type: news

Taking on the world: Lonnie Lu ’s experience with laryngeal cleft
Lonnie Lu and her mom at Boston Children’s Center for Airway Disorders. Not every little girl gets a visit from a Disney princess on her birthday, but Lonnie Lu received just such a surprise when Princess Elena stopped by her party last month. Her admiration may go beyond a love of colorful dresses. Minus one evil sorceress and an enchanted kingdom, the character’s tale of strength and resilience might as well be Lonnie Lu’s story, too. A mother’s intuition Now age 4, Lonnie Lu came into her parents Patti and Ricardo’s lives at 7 months old, when the couple decided to foster her and her older ...
Source: Thrive, Children's Hospital Boston - July 24, 2017 Category: Pediatrics Authors: Jessica Cerretani Tags: Diseases & Conditions Our Patients’ Stories Center for Airway Disorders Dr. Reza Rahbar laryngeal cleft Source Type: news

After bunion surgery, immediate x-rays predict recurrence risk
(Wolters Kluwer Health) For patients undergoing surgery to repair a bunion deformity of the foot, non-weight-bearing x rays taken immediately after surgery can provide a good estimate of the risk that the bunion will return over time, reports a study in the current issue of The Journal of Bone& Joint Surgery. The journal is published in partnership with Wolters Kluwer. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 24, 2017 Category: International Medicine & Public Health Source Type: news

Medical News Today: Epigastric hernia: Causes, repair, and recovery
What is an epigastric hernia? Learn about the causes of an epigastric hernia, the symptoms, how it is diagnosed, and what to expect from surgery. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - July 23, 2017 Category: Consumer Health News Tags: GastroIntestinal / Gastroenterology Source Type: news

How do open and arthroscopic approaches compare in the first 30 days following RCR?
Findings published online in the journal Arthroscopy assess risk of adverse events and return to the operating room (OR) during the initial 30-day postoperative period for patients undergoing open or arthroscopic rotator cuff repair (RCR).  (Source: Orthogate - Latest News)
Source: Orthogate - Latest News - July 22, 2017 Category: Orthopaedics Tags: Featured Editors Choice News Source Type: news

Taking my own advice: When the professional becomes a parent
As a disability expert, my whole career has been spent giving parents advice. I’ve given advice on parenting, doctors, child development, school and resources to support them. I was confident working with families and helping them navigate the often crazy and overwhelming world of special needs. But when I was 34 weeks pregnant with my own child, I found myself on the other side of the situation. My husband and I learned that our son, Jack, would be born with a cleft palate and micrognathia, or an undeveloped lower jaw. The extent of these facial differences wouldn’t be known until he was born. We met with doct...
Source: Thrive, Children's Hospital Boston - July 20, 2017 Category: Pediatrics Authors: Jennifer Ryan Tags: Diseases & Conditions Our Patients’ Stories Cleft and Craniofacial Center cleft lip and palate Dr. Carolyn Rogers Dr. Cory Resnick Pierre Robin sequence Source Type: news

High-dose vitamin D found to HEAL sunburns by activating skin repair genes... so why won't dermatologists recommend vitamin D?
(Natural News) The list of Vitamin D’s known health benefits continues to grow as scientists have now discovered it has the power to heal sunburned skin. In a new trial out of Case Western Reserve University that is the first of its kind, 20 participants were given a sunburn on their inner arm using a... (Source: NaturalNews.com)
Source: NaturalNews.com - July 19, 2017 Category: Consumer Health News Source Type: news

Rosalind Franklin University awarded NIH grant for research on neurological repair
(Rosalind Franklin University of Medicine and Science) A $2.8 million grant from the National Institutes of Health will help researchers at Rosalind Franklin University of Medicine and Science study how to replace neurons lost through stroke, traumatic brain and spinal injury and brain diseases including Alzheimer's. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 19, 2017 Category: International Medicine & Public Health Source Type: news

Intact Vascular launches Toba II BTK trial in EU
Intact Vascular today announced the European launch of the Toba II BTK clinical trial of its Tack endovascular system in combination with standard balloon angioplasty in the popliteal and tibial arteries for treating critical limb ischemia. The 1st European patient in the trial was enrolled by Dr. Marianne Brodmann and Dr. Peter Reif at Austria’s Medical University Graz, the Wayne, Penn.-based company said. “We are pleased to be the 1st center in Europe to commence enrollment in Toba II BTK. I believe the Tack endovascular system is a very promising technology designed to optimize dissection repair while l...
Source: Mass Device - July 18, 2017 Category: Medical Devices Authors: Fink Densford Tags: Catheters Clinical Trials Vascular Intact Vascular Source Type: news

STING is an essential mediator of the Ku70-mediated production of IFN-{lambda}1 in response to exogenous DNA
We previously identified Ku70, a subunit of a DNA repair protein complex, as a cytosolic DNA sensor that induces the production of interferon-1 (IFN-1) by human primary cells and cell lines. IFN-1 is a type III IFN and has similar antiviral activity to that of the type I IFNs (IFN-α and IFN-β). We observed that human embryonic kidney (HEK) 293T cells, which are deficient in the innate immune adaptor protein STING (stimulator of IFN genes), did not produce IFN-1 in response to DNA unless they were reconstituted with STING. Conversely, parental HEK 293 cells produced IFN-1 after they were exposed to exogenous DNA;...
Source: Signal Transduction Knowledge Environment - July 18, 2017 Category: Science Authors: Sui, H., Zhou, M., Imamichi, H., Jiao, X., Sherman, B. T., Lane, H. C., Imamichi, T. Tags: STKE Research Articles Source Type: news

Papers of note in Science 357 (6347)
This week’s articles highlight a newly discovered DNA repair system and the role of an inherited repressive epigenetic mark in fly embryonic development. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - July 18, 2017 Category: Science Authors: VanHook, A. M. Tags: STKE Editors ' Choice Source Type: news

Papers of note in Nature 547 (7662)
This week’s articles describe mechanisms that control the proliferation of cardiac cells during injury repair, personalized vaccines for treating cancer, and a mechanism by which malaria parasites sense host nutrients. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - July 18, 2017 Category: Science Authors: VanHook, A. M. Tags: STKE Editors ' Choice Source Type: news

Private Parts II: More things parents of boys need to know
While it can be uncomfortable for parents to talk about issues with their son’s private parts, abnormalities in the testicles and scrotum are common and treatable. One of my favorite parts of my job is sitting down with anxious families and being able to make the uncomfortable comfortable for them. I hope I can do that for you here in this guide to the most common testicular abnormalities seen in young boys. 1.    Undescended testicles A baby boy should have two testicles down in the scrotum. The best time to examine your son is while he soaks in a warm bath. If you’re unable to see or feel ...
Source: Thrive, Children's Hospital Boston - July 17, 2017 Category: Pediatrics Authors: Erin McNamara Tags: Ask the Expert Health & Wellness Department of Urology Erin McNamara Source Type: news

When Surgery Fails, Percutaneous Mitral Valve Repair Might Do the Job
(MedPage Today) -- Clipping reduces recurrent mitral regurgitation, per 1.5-year data (Source: MedPage Today Surgery)
Source: MedPage Today Surgery - July 17, 2017 Category: Surgery Source Type: news

Application of Theory of Planned Behavior in the motor vehicle repair and service industry - Abu Bakar E, Syamimi Isa N, Osman S.
The objective of this paper is to examine the determinant factors of consumer safety behavior in the motor vehicle repair and service industry. A total of five hundred respondents were chosen through stratified random sampling. Multiple regressions were us... (Source: SafetyLit)
Source: SafetyLit - July 14, 2017 Category: International Medicine & Public Health Tags: Occupational Issues Source Type: news

New gene mutation associated with Fanconi anemia
(University of W ü rzburg) Fanconi anemia is a rare genetic disease characterized by high cancer risk. Researchers of the University of W ü rzburg now have revealed a new Fanconi anemia gene that is involved in complex DNA repair processes and may also play a relevant role in cancer prevention. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 14, 2017 Category: International Medicine & Public Health Source Type: news

Long working hours linked to heightened irregular heart rhythm risk
Those working 55+hours/week 40% more likely to develop atrial fibrillation Related items fromOnMedica Working long hours raises risk of stroke Women doing heavy or shift work have lower fertility Shift work linked to higher coronary risk 12+ hour shifts heightens risk of burnout Do night shifts hinder body ’s ability to repair DNA? (Source: OnMedica Latest News)
Source: OnMedica Latest News - July 14, 2017 Category: UK Health Source Type: news

Not all astrocytes in the brain are the same, study finds
From afar, the billions of stars in our galaxy look indistinguishable, just as the billions of star-shaped astrocytes in our brains appear the same as each other. But UCLA researchers have now revealed that astrocytes, a type of brain cell that supports and protects neurons, aren ’t all the same. While stars might be categorized by their size, age and heat, the supportive brain cells vary when it comes to shape, molecular machinery and functioning.The findings,published today in the journal  Neuron, should make it easier for researchers to study how astrocytes relate to disease, or to develop drugs that aim...
Source: UCLA Newsroom: Health Sciences - July 13, 2017 Category: Universities & Medical Training Source Type: news

Gore touts 1st commercial use of Tag thoracic stent graft
W.L. Gore & Associates said today its Tag conformable thoracic stent graft was used in its 1st commercial procedure after the system won CE Mark approval in the European Union last month. The procedure was performed by Dr. Giovanni Torsello and Dr. Martin Austermann of Munster, Germany’s St. Franziskus Hospital, the Flagstaff, Ariz.-based company said. “The enhanced control capabilities this new delivery system allows could reduce many common complications that can occur if the stent graft is not placed correctly during the TEVAR procedure. Secondary interventions can be traumatic for patients and...
Source: Mass Device - July 13, 2017 Category: Medical Devices Authors: Fink Densford Tags: Business/Financial News Stent Grafts Vascular W.L. Gore & Associates Source Type: news

Getting and giving support for cleft lip and palate
Jack Dolan came into the world with a laugh. His mother, Erin, was mid-chuckle during labor when he was born — “a really joyful entrance,” she says. Looking down at her new son, she and her husband, Jimmy, breathed sighs of relief. “We took one look at him and thought, ‘He’s beautiful,’” she remembers. “We knew then that everything was going to be okay.” It was a happy celebration after a pregnancy sometimes marked by stress and anxiety. During ultrasonography, Erin and Jimmy had learned that Jack would be born with a bilateral cleft lip and palate. Erin, a nurse ...
Source: Thrive, Children's Hospital Boston - July 13, 2017 Category: Pediatrics Authors: Jessica Cerretani Tags: Diseases & Conditions Our Patients’ Stories Cleft and Craniofacial Center cleft lip and palate Dr. John Mulliken Olivia Oppel Source Type: news

Guanine glycation repair by DJ-1/Park7 and its bacterial homologs
DNA damage induced by reactive carbonyls (mainly methylglyoxal and glyoxal), called DNA glycation, is quantitatively as important as oxidative damage. DNA glycation is associated with increased mutation frequency, DNA strand breaks, and cytotoxicity. However, in contrast to guanine oxidation repair, how glycated DNA is repaired remains undetermined. Here, we found that the parkinsonism-associated protein DJ-1 and its bacterial homologs Hsp31, YhbO, and YajL could repair methylglyoxal- and glyoxal-glycated nucleotides and nucleic acids. DJ-1–depleted cells displayed increased levels of glycated DNA, DNA strand breaks,...
Source: ScienceNOW - July 13, 2017 Category: Science Authors: Richarme, G., Liu, C., Mihoub, M., Abdallah, J., Leger, T., Joly, N., Liebart, J.-C., Jurkunas, U. V., Nadal, M., Bouloc, P., Dairou, J., Lamouri, A. Tags: Molecular Biology reports Source Type: news

Of sizzling steaks and DNA repair
(Source: ScienceNOW)
Source: ScienceNOW - July 13, 2017 Category: Science Authors: Dingler, F. A., Patel, K. J. Tags: Physics perspective Source Type: news

UTA-linked startup TissueGen wins 'Medical Device Engineering Breakthrough' award
(University of Texas at Arlington) TissueGen won the award for its patented ELUTE ®   fiber, which provides pharmaceutical, therapeutic and medical device companies with topical and implantable drug delivery from biodegradable polymer-based fibers. Medical devices incorporating these fibers have the potential to revolutionize tissue engineering and regenerative medicine applications including spinal cord injury repair, nerve regeneration, orthopedic soft tissue repair, and many more. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - July 12, 2017 Category: Cancer & Oncology Source Type: news

First aid kit in some living organisms helps fix DNA after lengthy sun exposure
(Springer) Sunburn in living organisms is caused by ultraviolet (UV) light from the sun damaging the DNA in the cells. Many organisms, however, have an in-built mechanism for repairing the sun damage. In a study published in EPJ D, Katrine Aalb æ k Jepsen from the University of Southern Denmark, in Odense, and her colleague Ilia Solov'yov pinpoint the mechanism by which repair enzymes bind to the damaged site. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - July 12, 2017 Category: Biology Source Type: news

An ocean away: Care for laryngeal cleft brings Clara to Boston
My husband, Duncan, and I were living in London, England, when Clara was born. Although my pregnancy had started out like any other, I later developed severe polyhydramnios, an accumulation of amniotic fluid that can sometimes indicate the presence of certain congenital issues. After I delivered, it became clear that Clara had a congenital condition called esophageal atresia with tracheoesophageal fistula (EA/TEF). This condition meant that her esophagus (the tube that carries food from the mouth to the stomach) hadn’t developed properly and didn’t connect to her stomach, but that her esophagus and windpipe wer...
Source: Thrive, Children's Hospital Boston - July 11, 2017 Category: Pediatrics Authors: Natascha Kiernan Tags: Diseases & Conditions Our Patients’ Stories Center for Airway Disorders Dr. Reza Rahbar laryngeal cleft Source Type: news

Neural stem cells steered by electric fields in rat brain
(University of California - Davis) Electric fields can be used to guide neural stem cells transplanted into the brain towards a specific location. The research, published July 11 in the journal Stem Cell Reports, opens possibilities for effectively guiding stem cells to repair brain damage. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - July 11, 2017 Category: Biology Source Type: news

Hidden Herpes Virus May Play Key Role in MS, Other Brain Disorders
The ubiquitous human herpesvirus 6 (HHV-6) may play a critical role in impeding the brain ’s ability to repair itself in diseases like multiple sclerosis. The findings, which appear in the journal Scientific Reports, may help explain the differences in severity in symptoms that many people with the disease experience. (Source: University of Rochester Medical Center Press Releases)
Source: University of Rochester Medical Center Press Releases - July 10, 2017 Category: Universities & Medical Training Authors: University of Rochester Medical Center Source Type: news

FDA OKs Intact Vascular IDE app for 6-month endpoint in BTK Tack angioplasty trial
Intact Vascular said today that the FDA approved an investigational device exemption supplemental application to modify the primary endpoint in a below-the-knee clinical trial of its Tack optimized balloon angioplasty from 12 months to 6 months. The Tack endovascular system is designed to repair dissections that occur as a complication of balloon angioplasty. The system allows operating physicians to repair dissections with only a small amount of foreign material in the artery, the Wayne, Penn.-based company said. The Toba II BTK study is a prospective, multi-center, single-arm study which looks to investigate the saf...
Source: Mass Device - July 10, 2017 Category: Medical Devices Authors: Fink Densford Tags: Clinical Trials Food & Drug Administration (FDA) Vascular Intact Vascular Source Type: news

Study identifies new gene mutation associated with defective DNA repair and Fanconi anemia
(JCI Journals) Fanconi anemia is a rare genetic disease characterized by hematologic symptoms and high cancer risk. Mutations in nearly 20 different genes have been identified in patients with Fanconi anemia. In a study published this week in the JCI, work from Detlev Schinder's group at the University of Wurzburg reveals a new Fanconi anemia gene, RFWD3, that is involved in complex DNA repair processes and may also play a relevant role in cancer risk. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - July 10, 2017 Category: Cancer & Oncology Source Type: news

Health Ranger demonstrates EMP-proof John Deere tractor repair and maintenance (VIDEO)
(Natural News) In the following videos, prepper and survival skills educator Mike Adams (the Health Ranger) walks you through a fuel boot replacement and basic maintenance on an EMP-proof 1970s John Deere tractor. Because these tractors use no electronics or circuit boards, they are impervious to solar flares or EMP attacks. So knowing how to... (Source: NaturalNews.com)
Source: NaturalNews.com - July 8, 2017 Category: Consumer Health News Source Type: news

Medical News Today: Vitamin D may help to treat sunburn, study suggests
Researchers found that high-dose vitamin D not only led to a reduction in sunburn-induced skin inflammation, but it also activated skin repair genes. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - July 7, 2017 Category: Consumer Health News Tags: Dermatology Source Type: news