Estimating the direct effects of the genetic liabilities to bipolar disorder, schizophrenia, and behavioral traits on suicide attempt using a multivariable Mendelian randomization approach - Cabrera-Mendoza B, Aydin N, Fries GR, Docherty AR, Walss-Bass C, Polimanti R.
In this study, we aimed to explore the effect of BD and SZ genetic liabilities on SA, also considering the contribution of behavioral traits, socioeconomi... (Source: SafetyLit)
Source: SafetyLit - February 26, 2024 Category: International Medicine & Public Health Tags: Research Methods, Surveillance and Codes, Models Source Type: news

Neurogenetic and multi-omic sources of overlap among sensation seeking, alcohol consumption, and alcohol use disorder - Miller AP, Gizer IR.
Sensation seeking is bidirectionally associated with levels of alcohol consumption in both adult and adolescent samples, and shared neurobiological and genetic influences may in part explain these associations. Links between sensation seeking and alcohol u... (Source: SafetyLit)
Source: SafetyLit - February 26, 2024 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

The effects of childhood maltreatment, recent interpersonal and noninterpersonal stress, and HPA-axis multilocus genetic variation on prospective changes in adolescent depressive symptoms: a multiwave longitudinal study - Sun K, Cao C.
Based on a multiwave, two-year prospective design, this study is the first to examine the extent to which multilocus hypothalamic-pituitary-adrenal axis (HPA axis)-related genetic variants, childhood maltreatment, and recent stress jointly predicted prospe... (Source: SafetyLit)
Source: SafetyLit - February 26, 2024 Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news

Links 2/24/2024
On the shared genetic memories between us, the cat and the fly aeon Anthony L) Astronomers Discover the Brightest Known Object in the Universe, Shining 500 Trillion Times as Bright as the Sun Smithsonian (Anthony L) Fascinating Obscure Texts from Ancient Greece and Rome Tales of Times Forgotten…#anthonyl #astronomersdiscover #universe #sunsmithsonian #ancientgreece #rometales #timesforgotten (Source: Reuters: Health)
Source: Reuters: Health - February 24, 2024 Category: Consumer Health News Source Type: news

Alabama Embryo Ruling Raises Questions About IVF And Testing For Fatal Genetic Diseases
The Alabama Embryo Ruling of February 2024 means that parents using IVF and preimplantation genetic diagnosis to reduce the risk of having a child with a lethal genetic condition may be blocked from doing so in Alabama. (Source: Healthcare News)
Source: Healthcare News - February 24, 2024 Category: Pharmaceuticals Authors: Ellen Matloff, Contributor Tags: Healthcare /healthcare Innovation /innovation business pharma & standard Source Type: news

Ancient glue, crochet microbes, and more stories you might have missed this week
How did horses spread across North America? What can ancient DNA tell us about Down syndrome in people who lived long ago? And why is one microbiologist making bacteria out of yarn? Check out the answers below in some of our favorite selections from Science ’s daily newsletter, Science Adviser . Indigenous and Western scientists team up to reconstruct the history of North American horses Established in 1923, the Newcomb Cleveland Prize is AAAS’s oldest prize, awarded annually to the authors of an “outstanding” Science paper. This year’...
Source: ScienceNOW - February 23, 2024 Category: Science Source Type: news

Poised to be first widely consumed gene-edited animals, virus-resistant pigs trot toward market
Pigs, cattle, and other livestock with edited genes are still far from most dinner plates, but a U.K. company has taken a big step toward the supermarket by engineering several commercial breeds of pigs to be resistant to a virus that devastates the swine industry. The firm, Genus plc, hopes that by year’s end the U.S. Food and Drug Administration (FDA) will formally approve the pigs for widespread human consumption, a first for a gene-edited animal. Alison Van Eenennaam, an animal geneticist at the University of California, Davis, is cheering the news. “There’s no point having a pig getting sick and dying if t...
Source: ScienceNOW - February 23, 2024 Category: Science Source Type: news

Faster Cures, More Genetic Treatments: A Q & A With NIH's Joni Rutter
(MedPage Today) -- You might have seen the name on a listing of NIH institutes and centers: the National Center for Advancing Translational Sciences (NCATS). "What the heck are they up to?" you may have thought. To answer that question, MedPage... (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - February 23, 2024 Category: Hematology Source Type: news

EMA Approves Two Therapies for Rare Genetic Diseases EMA Approves Two Therapies for Rare Genetic Diseases
Treatments for amyotrophic lateral sclerosis and paroxysmal nocturnal hemoglobinuria have been given marketing authorization by the European Medicines Agency.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - February 23, 2024 Category: Cancer & Oncology Tags: Hematology-Oncology Source Type: news

Geneticist and opera singer team up to study how music can improve health
Giants in their fields of music and science are merging their knowledge to propel advancements in body and mind. A recent international gathering of researchers, therapists and artists took stock of what is known and what is yet to be discovered. Jeffrey Brown reports for our ongoing arts and…#giants #jeffreybrown #canvas (Source: Reuters: Health)
Source: Reuters: Health - February 23, 2024 Category: Consumer Health News Source Type: news

News at a glance: Protecting a queen, cell therapy for solid tumors, and a UV telescope
CONSERVATION U.S. protects iconic marine snail The queen conch, a large marine snail known for its showy shell and delectable flesh, has been added to the U.S. government’s list of species threatened with extinction. Scientists at the National Oceanic and Atmospheric Administration (NOAA) said the species ( Strombus gigas , pictured), which is native to the Caribbean region and grows up to 35 centimeters long, needs protection because populations are sparse, scattered, and heavily overfished. NOAA’s listing decision, issued on 14 February, has no immediate impact but authorizes the age...
Source: ScienceNOW - February 22, 2024 Category: Science Source Type: news

A deadly viral illness is exploding in West Africa. Researchers are scrambling to figure out why
Reporting for this story was supported by the Pulitzer Center. Irrua, Nigeria, and Kenema, Sierra Leone— Sitting on a bench outside the Irrua Specialist Teaching Hospital (ISTH) in Edo state in southwestern Nigeria in September 2023, Muhammed Luqman Dagana recounted his ordeal earlier in the year with Lassa fever, a deadly hemorrhagic disease of West Africa. At first the 33-year-old wasn’t alarmed—his fever, headache, body aches, and cough were innocuous enough. A doctor at his local clinic gave him antibiotics for typhoid fever and antimalarial drugs. But his symptoms persisted, so he tried anoth...
Source: ScienceNOW - February 22, 2024 Category: Science Source Type: news

Join NCBI at TAGC 2024
March 6-10 in Washington, D.C.  We look forward to seeing you in person at The Allied Genetics Conference (TAGC), March 6-10, 2024, in the Washington D.C. metro area. NCBI staff will participate in a variety of activities and events, including hosting a hands-on workshop: Exploring and downloading NCBI data with NCBI Datasets. We’re also excited … Continue reading Join NCBI at TAGC 2024 → (Source: NCBI Insights)
Source: NCBI Insights - February 22, 2024 Category: Databases & Libraries Authors: NCBI Staff Tags: What's New Comparative Genomics Resource (CGR) Gene Expression Omnibus (GEO) NCBI Datasets RefSeq Source Type: news

I discovered a way to identify the millions of species on Earth after a lightbulb moment in the supermarket
I developed DNA barcoding in my back yard using a UV light and a white sheet to collect the moths of my childhood. I believe it could help discover all life on the planetAs a child, I used to roam the countryside collecting moths and butterflies on the edge of the Great Lakes in Canada. It was as idyllic as it sounds: by day, I would scour the fields and forests for butterflies. At night, I would leave a white sheet and UV light in my back yard, rising at 5am to inspect the harvest of moths.By the time I was an adult, I could identify about 700 butterfly and moth species by sight, deciphering the stripes, dots and colours ...
Source: Guardian Unlimited Science - February 22, 2024 Category: Science Authors: Paul Hebert Tags: Wildlife Genetics Biology Environment Science Zoology Butterflies Insects Biodiversity Conservation Source Type: news

Air pollution could be significant cause of dementia – even for those not predisposed
People in areas of high PM2.5 concentrations had higher amounts of amyloid plaques in brainAir pollution from traffic is linked to some of the more severe forms of dementia, and could be a significant cause of the condition among those who are not already genetically predisposed to it, research suggests.Research carried out in Atlanta, Georgia, found that people with higher exposure to traffic-related fine particulate matter air pollution were more likely to have high amounts of the amyloid plaques in their brains that are associated with Alzheimer ’s.Continue reading... (Source: Guardian Unlimited Science)
Source: Guardian Unlimited Science - February 21, 2024 Category: Science Authors: Damien Gayle Tags: Air pollution Environment US news Dementia Alzheimer's World news Source Type: news