Dog Person? It May Be in Your Genes
Scientists calculated that genetics is responsible for 57 percent of dog ownership in women and 51 percent in men. (Source: NYT Health)
Source: NYT Health - May 21, 2019 Category: Consumer Health News Authors: NICHOLAS BAKALAR Tags: Genetics and Heredity Twins Dogs Source Type: news

Your DNA Might Determine Whether You're a Dog Lover
TUESDAY, May 21, 2019 -- Could a love for canines be contained in your genes? New research from Europe suggests that's so after comparing the genetic makeup of more than 35,000 twin pairs with dog ownership. The researchers concluded that genetic... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - May 21, 2019 Category: General Medicine Source Type: news

National Institutes of Health launches $9 million genetic testing center at UC Davis
The federal government ’s medical research agency is launching a new center to develop genetic editing tools with the University of California Davis.  The National Institutes of Health is funding the new center with a $9 million grant announced Monday. Those dollars are earmarked for primate research projects to impro ve the safety and efficacy of genetic editing tools. The new center has been dubbed the UC Davis Nonhuman Primate Testing Center for Evaluation of Somatic Cell Genome Editing Tools. The… (Source: bizjournals.com Health Care:Biotechnology headlines)
Source: bizjournals.com Health Care:Biotechnology headlines - May 21, 2019 Category: Biotechnology Authors: Felicia Alvarez Source Type: news

DNA test proves former care worker is entitled to £50m country estate
Jordan Adlard Rogers inherits 1,536-acre Cornwall estate after proving owner was his fatherA former care worker has inherited a £50m country estate after a DNA test proved he was the son of its deceased owner.Jordan Adlard Rogers, 31, found out his father was the aristocrat Charles Rogers after his death in 2018 and has now moved into the 1,536-acre Penrose estate in Cornwall, which his family has lived in for generations.Continue reading... (Source: Guardian Unlimited Science)
Source: Guardian Unlimited Science - May 21, 2019 Category: Science Authors: Amy Walker Tags: Cornwall UK news Genetics Science Source Type: news

Summit charts a course to uncover the origins of genetic diseases
(DOE/Oak Ridge National Laboratory) A team led by Ivaylo Ivanov of Georgia State University used the 200-petaflop IBM AC922 Summit system, the world's smartest and most powerful supercomputer, to develop an integrative model of the transcription preinitiation complex (PIC), a complex of proteins vital to gene expression. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - May 21, 2019 Category: Cancer & Oncology Source Type: news

Can Next-Gen Sequencing Save Money in Lung Cancer Genetic Testing?
A computer modeling analysis studied the use of NGS and its costs in patients with metastatic non –small-cell lung cancer. (Source: CancerNetwork)
Source: CancerNetwork - May 21, 2019 Category: Cancer & Oncology Authors: Dave Levitan Source Type: news

Developing biosecurity tool to detect genetically engineered organisms in the wild
(Worcester Polytechnic Institute) If a genetically or synthetically engineered organism gets into the environment, how will we tell it apart from the millions of naturally occurring microorganisms? Recently, the US government and research scientists have identified a need for new tools that can detect engineered organisms that have been accidentally or intentionally released beyond the lab. With scientists from Raytheon and other universities, WPI chemical engineer Eric Young is helping develop a detection tool based on DNA signatures. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - May 21, 2019 Category: International Medicine & Public Health Source Type: news

IRF2 transcriptionally induces GSDMD expression for pyroptosis
Gasdermin-D (GSDMD) is cleaved by caspase-1, caspase-4, and caspase-11 in response to canonical and noncanonical inflammasome activation. Upon cleavage, GSDMD oligomerizes and forms plasma membrane pores, resulting in interleukin-1β (IL-1β) secretion, pyroptotic cell death, and inflammatory pathologies, including periodic fever syndromes and septic shock—a plague on modern medicine. Here, we showed that IRF2, a member of the interferon regulatory factor (IRF) family of transcription factors, was essential for the transcriptional activation of GSDMD. A forward genetic screen with N-ethyl-N-nitrosourea (ENU)&...
Source: Signal Transduction Knowledge Environment - May 21, 2019 Category: Science Authors: Kayagaki, N., Lee, B. L., Stowe, I. B., Kornfeld, O. S., O'Rourke, K., Mirrashidi, K. M., Haley, B., Watanabe, C., Roose-Girma, M., Modrusan, Z., Kummerfeld, S., Reja, R., Zhang, Y., Cho, V., Andrews, T. D., Morris, L. X., Goodnow, C. C., Bertram, E. M., Tags: STKE Research Articles Source Type: news

Phoenix genetic test maker gets $15M in funding; bioscience leader joins board
The latest capital infusion comes several months after a previous $9 million raise, all of which is funding the company to develop a test to ensure cancer patients can get more personalized medical care. (Source: bizjournals.com Health Care News Headlines)
Source: bizjournals.com Health Care News Headlines - May 20, 2019 Category: Health Management Authors: Angela Gonzales Source Type: news

Phoenix genetic test maker gets $15M in funding; bioscience leader joins board
The latest capital infusion comes several months after a previous $9 million raise, all of which is funding the company to develop a test to ensure cancer patients can get more personalized medical care. (Source: bizjournals.com Health Care:Biotechnology headlines)
Source: bizjournals.com Health Care:Biotechnology headlines - May 20, 2019 Category: Biotechnology Authors: Angela Gonzales Source Type: news

MyHeritage expands into health-focused DNA testing
The Israel-based company is offering 11 genetic risk tests, three polygenic risk tests  and 15 carrier status reports. (Source: mobihealthnews)
Source: mobihealthnews - May 20, 2019 Category: Information Technology Source Type: news

Reneo Pharmaceuticals Raises $50 Million to Develop Therapeutics to Treat Genetic Mitochondrial Diseases
SAN DIEGO, May 20, 2019 -- (Healthcare Sales & Marketing Network) -- Reneo Pharmaceuticals, a clinical stage pharmaceutical company, today announced that it has completed a $50 million Series A financing to develop therapies for diseases associated with d... Biopharmaceuticals, Venture Capital Reneo Pharmaceuticals, mitochondrial diseases (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - May 20, 2019 Category: Pharmaceuticals Source Type: news

Mesothelioma Clinical Trial Exploring Family Predisposition
The National Cancer Institute has opened a clinical trial using mesothelioma patients and their family members to explore predisposition to the cancer and potential solutions to negating it. The trial is a follow up to an earlier study of a genetic mutation that creates susceptibility to various cancers but a longer-than-normal survival with platinum-based chemotherapy treatment. “This is an important, long-term study that could have implications not only for a patient, but for family members, too,” Dr. Raffit Hassan, NCI senior investigator told The Mesothelioma Center at Asbestos.com. “Progress can be m...
Source: Asbestos and Mesothelioma News - May 20, 2019 Category: Environmental Health Authors: Matt Mauney Source Type: news

Synthetic biologists hack bacterial sensors
(Rice University) Synthetic biologists have hacked bacterial sensing with a plug-and-play system that could be used to mix-and-match tens of thousands of sensory inputs and genetic outputs. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - May 20, 2019 Category: Biology Source Type: news

What Causes Macrocephaly?
Discussion “Macrocephaly is defined as [an occipitofrontal circumference or head circumference, OFC ] of> 2 standard deviations above the mean or above the 97th percentage for a given age, and gender, or when serial measurement shows progressive enlargement, crossing of one or more major percentiles, or when there is an increase in OFC> 2 cm/month in the first 6 months of life.” Megalencephaly is enlargement of the brain parenchyma. The OFC should be measured using a non-elastic tape which surrounds the head along the line of the glabella and posterior occipital protrusion. There are ethnic differences f...
Source: PediatricEducation.org - May 20, 2019 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

Predictive links between genetic vulnerability to depression and trajectories of warmth and conflict in the mother-adolescent and father-adolescent relationships - Brouillard C, Brendgen M, Vitaro F, Dionne G, Boivin M.
The present study used a genetically informed design of twins raised in the same family (375 monozygotic and 290 dizygotic twins; 50.2% girls) to examine the association between adolescents' genetic risk for depressive symptoms and the course of the parent... (Source: SafetyLit)
Source: SafetyLit - May 18, 2019 Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news

A Rare Genetic Mutation Leads to Cancer. The Fix May Already Be in the Drugstore.
A common dietary supplement may help overcome mutations in the Pten gene. Should patients take it? (Source: NYT Health)
Source: NYT Health - May 17, 2019 Category: Consumer Health News Authors: GINA KOLATA Tags: Breast Cancer Genetics and Heredity Drugs (Pharmaceuticals) Clinical Trials Dietary Supplements and Herbal Remedies Beth Israel Deaconess Medical Center Boston Children's Hospital Science (Journal) Source Type: news

UC Davis features micropublications
microPublication.org publishes brief, novel findings, negative and/or reproduced results, and results which may lack a broader scientific narrative. Each article is peer reviewed and assigned a DOI. Included data is curated and, upon publication, deposited in third party referential databases (when available). Recently UC Davis featured an article, ‘Small Science Snippets: Micropubs Help Share Discoveries‘ about how one of their researchers used a micropublication to publish their results. Micropublish your results today! (Source: WormBase)
Source: WormBase - May 17, 2019 Category: Genetics & Stem Cells Authors: Ranjana Kishore Tags: brief communication community external website news micropublication Source Type: news

Clinical trial at IU School of Medicine improves treatment of genetic rickets
(Indiana University) A new study shows a drug developed in conjuction with investigators at Indiana University School of Medicine to alleviate symptoms of a rare musculoskeletal condition is significantly more effective than conventional therapies. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - May 17, 2019 Category: International Medicine & Public Health Source Type: news

Owning a dog is influenced by our genetic make-up
(Uppsala University) A team of Swedish and British scientists have studied the heritability of dog ownership using information from 35,035 twin pairs from the Swedish Twin Registry. The new study suggests that genetic variation explains more than half of the variation in dog ownership, implying that the choice of getting a dog is heavily influenced by an individual's genetic make-up. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - May 17, 2019 Category: International Medicine & Public Health Source Type: news

Genomic Data Carve A New Path For Consumers, Clinical Trials
Genetic testing has changed drastically over the past decade with improvements to technology, turn-around-time, and scope of tests available. Millions of people have had genetic testing and mountains of baseline data now exist. Using these data effectively is the next challenge in front of us. (Source: Forbes.com Healthcare News)
Source: Forbes.com Healthcare News - May 16, 2019 Category: Pharmaceuticals Authors: Ellen Matloff, Contributor Source Type: news

Cystic fibrosis scandal: Little Eve makes 65 roses in plea for life-saving drugs
A TODDLER with cystic fibrosis will deliver a bunch of 65 roses to Prime Minister Theresa May today, to plead for life-saving drugs to be available on the NHS. Eve Jones, one, was born with the cruel, deteriorating genetic condition, but wonder drug Orkambi could add decades to her life. (Source: Daily Express - Health)
Source: Daily Express - Health - May 16, 2019 Category: Consumer Health News Source Type: news

Latest T-Cell Study Opens for Mesothelioma Patients
Sarah Cannon Research Institute in Nashville, Tennessee, and MD Anderson Cancer Center in Houston have opened a much-anticipated clinical trial involving a novel T-cell therapy for patients with mesothelioma. The two institutions are establishing dosage levels and measuring efficacy of TC-210, a type of immunotherapy that targets mesothelin, a cell surface protein highly expressed in several cancers. The study also is open to patients with certain types of bile duct, ovarian and non-small cell lung cancer. Participation is based upon individual levels of mesothelin expression. Researchers at the two centers are hoping to ...
Source: Asbestos and Mesothelioma News - May 16, 2019 Category: Environmental Health Authors: Matt Mauney Source Type: news

Genus shares surge on deal to market gene-edited pigs in China
British livestock genetics firm Genus agreed on Thursday to license its know-how on virus-resistant pigs to Beijing Capital Agribusiness Co Ltd, which will seek regulatory approval for the pigs in the world's biggest pork market. (Source: Reuters: Health)
Source: Reuters: Health - May 16, 2019 Category: Consumer Health News Tags: healthNews Source Type: news

AHA News: More Clues to the Genetics Behind an Inherited Cholesterol Disorder
Title: AHA News: More Clues to the Genetics Behind an Inherited Cholesterol DisorderCategory: Health NewsCreated: 5/15/2019 12:00:00 AMLast Editorial Review: 5/16/2019 12:00:00 AM (Source: MedicineNet Cholesterol General)
Source: MedicineNet Cholesterol General - May 16, 2019 Category: Cardiology Source Type: news

Common diarrhea pathogen unknown to many people
(BfR Federal Institute for Risk Assessment) Salmonella, genetically modified foods and microplastics in food head the awareness scale of health and consumer topics in Germany. Despite this, more than three quarters of Germans regard food as safe. This is the result of the latest Consumer Monitor -- a representative population survey carried out by the German Federal Institute for Risk Assessment (BfR). Most people are concerned about antimicrobial resistance, microplastics and residues of plant protection products in food. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - May 16, 2019 Category: International Medicine & Public Health Source Type: news

Novel tool used to mine clinical data and identify causative gene in childhood epilepsy
(Children's Hospital of Philadelphia) Researchers systematically compared phenotypes, or clinical data, of patients with severe childhood epilepsies through a novel analysis strategy and looked for common genetic causes in patients who had similar clinical presentations. This is the first time that such an analysis of clinical data has been used to identify novel genetic causes of neurological disorders. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - May 16, 2019 Category: Biology Source Type: news

The global invasion routes of the red swamp crayfish, described based on genetics
(Spanish National Research Council (CSIC)) A study led by researchers at the Do ñ ana Biological Station of the Spanish National Research Council (CSIC), in collaboration with institutions in Europe, America and Asia, has identified the main introduction routes of the red swamp crayfish, Procambarus clarkii, during its global-scale invasion. This North American species is the most widely spread freshwater crayfish worldwide, and is one of the worst invasive species due to its impact on the structure and functioning of freshwater ecosystems. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - May 16, 2019 Category: Biology Source Type: news

Cambridge scientists create world ’s first living organism with fully redesigned DNA
Researchers create altered synthetic genome, in move with potential medical benefitsScientists have created the world ’s first living organism that has a fully synthetic and radically altered DNA code.The lab-made microbe, a strain of bacteria that is normally found in soil and the human gut, is similar to its natural cousins but survives on a smaller set of genetic instructions.Continue reading... (Source: Guardian Unlimited Science)
Source: Guardian Unlimited Science - May 16, 2019 Category: Science Authors: Ian Sample Science editor Tags: Genetics Science Synthetic biology E coli UK news Health University of Cambridge Source Type: news

Reactivation of PTEN tumor suppressor for cancer treatment through inhibition of a MYC-WWP1 inhibitory pathway
Activation of tumor suppressors for the treatment of human cancer has been a long sought, yet elusive, strategy. PTEN is a critical tumor suppressive phosphatase that is active in its dimer configuration at the plasma membrane. Polyubiquitination by the ubiquitin E3 ligase WWP1 (WW domain–containing ubiquitin E3 ligase 1) suppressed the dimerization, membrane recruitment, and function of PTEN. Either genetic ablation or pharmacological inhibition of WWP1 triggered PTEN reactivation and unleashed tumor suppressive activity. WWP1 appears to be a direct MYC (MYC proto-oncogene) target gene and was critical for MYC-drive...
Source: ScienceNOW - May 16, 2019 Category: Science Authors: Lee, Y.-R., Chen, M., Lee, J. D., Zhang, J., Lin, S.-Y., Fu, T.-M., Chen, H., Ishikawa, T., Chiang, S.-Y., Katon, J., Zhang, Y., Shulga, Y. V., Bester, A. C., Fung, J., Monteleone, E., Wan, L., Shen, C., Hsu, C.-H., Papa, A., Clohessy, J. G., Teruya-Felds Tags: Genetics, Medicine, Diseases, Online Only r-articles Source Type: news

Identification of a regeneration-organizing cell in the Xenopus tail
Unlike mammals, Xenopus laevis tadpoles have a high regenerative potential. To characterize this regenerative response, we performed single-cell RNA sequencing after tail amputation. By comparing naturally occurring regeneration-competent and -incompetent tadpoles, we identified a previously unrecognized cell type, which we term the regeneration-organizing cell (ROC). ROCs are present in the epidermis during normal tail development and specifically relocalize to the amputation plane of regeneration-competent tadpoles, forming the wound epidermis. Genetic ablation or manual removal of ROCs blocks regeneration, whereas trans...
Source: ScienceNOW - May 16, 2019 Category: Science Authors: Aztekin, C., Hiscock, T. W., Marioni, J. C., Gurdon, J. B., Simons, B. D., Jullien, J. Tags: Cell Biology, Development r-articles Source Type: news

Single-cell genomics identifies cell type-specific molecular changes in autism
Despite the clinical and genetic heterogeneity of autism, bulk gene expression studies show that changes in the neocortex of autism patients converge on common genes and pathways. However, direct assessment of specific cell types in the brain affected by autism has not been feasible until recently. We used single-nucleus RNA sequencing of cortical tissue from patients with autism to identify autism-associated transcriptomic changes in specific cell types. We found that synaptic signaling of upper-layer excitatory neurons and the molecular state of microglia are preferentially affected in autism. Moreover, our results show ...
Source: ScienceNOW - May 16, 2019 Category: Science Authors: Velmeshev, D., Schirmer, L., Jung, D., Haeussler, M., Perez, Y., Mayer, S., Bhaduri, A., Goyal, N., Rowitch, D. H., Kriegstein, A. R. Tags: Development, Medicine, Diseases, Neuroscience reports Source Type: news

Supporting tumor suppression
(Source: ScienceNOW)
Source: ScienceNOW - May 16, 2019 Category: Science Authors: Ray, L. B. Tags: Genetics, Medicine, Diseases twis Source Type: news

Amgen Showcases Oncology Pipeline At ASCO 2019
Data From Largest Oncology Pipeline in Company's History First-in-Human Data Evaluating Investigational AMG 510, the First KRASG12C Inhibitor to Reach Clinical Stage, in Solid Tumors Potential Versatility of BiTE® Immuno-oncology Platform Reinforced With Phase 1 Asset Updates THOUSAND OAKS, Calif., May 15, 2019 /PRNewswire/ -- Amgen (NASDAQ: AMGN) today announced that data from its oncology pipeline will be presented at the 55th Annual Meeting of the American Society of Clinical Oncology (ASCO) in Chicago, May 31-June 4, 2019. Seven investigational assets will be featured across a range of hematologic malignan...
Source: Amgen News Release - May 15, 2019 Category: Pharmaceuticals Tags: Uncategorized Source Type: news

Woman who thought she was clumsy is diagnosed with degenerative condition and now needs a walker
Madelyn Frederick, 20, from Dallas, Texas, was diagnosed in March 2013 with Friedreich's Ataxia, a rare genetic disease that affects the nervous system and causes a progressive loss of movement. (Source: the Mail online | Health)
Source: the Mail online | Health - May 15, 2019 Category: Consumer Health News Source Type: news

World ’s first living organism with fully redesigned DNA created
Researchers create altered synthetic genome, in move with potential medical benefitsScientists have created the world ’s first living organism that has a fully synthetic and radically altered DNA code.The lab-made microbe, a strain of bacteria that is normally found in soil and the human gut, is similar to its natural cousins but survives on a smaller set of genetic instructions.Continue reading... (Source: Guardian Unlimited Science)
Source: Guardian Unlimited Science - May 15, 2019 Category: Science Authors: Ian Sample Science editor Tags: Genetics Science Synthetic biology E coli UK news Health University of Cambridge Source Type: news

AHA News: More Clues to the Genetics Behind an Inherited Cholesterol Disorder
WEDNESDAY, May 15, 2019 (American Heart Association News) -- High cholesterol is a risk factor for heart disease, but not all forms of it are the same. An underdiagnosed genetic condition called familial hypercholesterolemia can cause dangerously... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - May 15, 2019 Category: General Medicine Source Type: news

WormBase updated to the WS270 release
Alliance orthologs Starting from WS270 we are using the Alliance of Genome Resources for orthologs between model organism genes. This should be more comprehensive and include the latest data from our sister databases. VC2010 genome An assembly and geneset of the VC2010 C.elegans strain has been added and work is ongoing to improve the integration and display of strain specific data. Additionally more mappings of N2 annotation will be included in future releases. (Source: WormBase)
Source: WormBase - May 15, 2019 Category: Genetics & Stem Cells Authors: Michael Paulini Tags: news release notes Alliance of Genome Resources WS270 Source Type: news

Phys Ed: To Move Is to Thrive. It ’ s in Our Genes.
A need and desire to be in motion may have been bred into our DNA before we even became humans. (Source: NYT Health)
Source: NYT Health - May 15, 2019 Category: Consumer Health News Authors: GRETCHEN REYNOLDS Tags: Genetics and Heredity DNA (Deoxyribonucleic Acid) Exercise Weight Medicine and Health Source Type: news

NHS to fund drug that prolongs lives of children with muscle-wasting disease
Spinraza to be made available to spinal muscular atrophy patientsA drug that could prolong the lives of children with a rare muscle-wasting disease has been approved by the NHS in England after lengthy negotiations with the manufacturer over the high price.Spinraza could help between 600 and 1,200 children and adults in England and Wales who have the genetic condition spinal muscular atrophy (SMA). It affects the nerves in the spinal cord, making muscles weaker and causing problems with movement, breathing and swallowing. It can shorten the life expectancy of babies and toddlers.Continue reading... (Source: Guardian Unlimited Science)
Source: Guardian Unlimited Science - May 15, 2019 Category: Science Authors: Sarah Boseley Health editor Tags: NHS Health Society UK news Pharmaceuticals industry Business Drugs Science Source Type: news

Blood biopsy: New technique enables detailed genetic analysis of cancer cells
(University of Michigan) A new way to cleanly separate out cancer cells from a blood sample enables comprehensive genetic profiling of the cancer cells, which could help doctors target tumors and monitor treatments more effectively. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - May 15, 2019 Category: Cancer & Oncology Source Type: news

First ever treatment for children with rare muscle-wasting condition
The NHS will provide a promising new treatment that can prolong the lives of children with a rare genetic condition under a deal with the manufacturer. (Source: NHS Networks)
Source: NHS Networks - May 15, 2019 Category: UK Health Source Type: news

Mitochondrial DNA, a powerful tool to decipher ancient human civilization from domestication to music, and to uncover historical murder cases - Merheb M, Matar R, Hodeify R, Siddiqui SS, Vazhappilly CG, Marton J, Azharuddin S, Al Zouabi H.
Mitochondria are unique organelles carrying their own genetic material, independent from that in the nucleus. This review will discuss the nature of mitochondrial DNA (mtDNA) and its levels in the cell, which are the key elements to consider when trying to... (Source: SafetyLit)
Source: SafetyLit - May 14, 2019 Category: International Medicine & Public Health Tags: Commentary Source Type: news

Rare genetic variations may contribute to PCOS
New research published in theJournal of Clinical Endocrinology and Metabolismhas identified rare genetic variations that may contribute to the heritability of PCOS.Endocrinology Advisor (Source: Society for Endocrinology)
Source: Society for Endocrinology - May 14, 2019 Category: Endocrinology Source Type: news

Early term infants less likely to breastfeed
(Mary Ann Liebert, Inc./Genetic Engineering News) A new, prospective study provides evidence that 'early term' infants (those born at 37-38 weeks) are less likely than full-term infants to be breastfeed within the first hour and at one month after birth. The early-term infants also had lower exclusive breastfeeding and lower breastfeeding intensity during the first 72 hours in the hospital and at one month. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - May 14, 2019 Category: International Medicine & Public Health Source Type: news

Is a broadly effective dengue vaccine even possible?
(Mary Ann Liebert, Inc./Genetic Engineering News) Dengue is on the rise, with about 20,000 patients dying each year from this mosquito-borne disease, yet despite ongoing efforts a broadly effective dengue vaccine is not available. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - May 14, 2019 Category: Biology Source Type: news

Predictive association of smoking with depressive symptoms: a longitudinal study of adolescent twins - Ranjit A, Buchwald J, Latvala A, Heikkil ä K, Tuulio-Henriksson A, Rose RJ, Kaprio J, Korhonen T.
We examined the longitudinal association of cigarette smoking with subsequent depressive symptoms during adole... (Source: SafetyLit)
Source: SafetyLit - May 13, 2019 Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news

Researchers identify faster, more effective drug combination regimens to treat tuberculosis
Tuberculosis is a potentially deadly though curable disease. Each year about 10 million people develop active cases, and 1.6 million people die. In addition, about 1.7 billion people around the world are infected with TB bacteria, which can lie dormant for weeks to years, then become active and cause disease in up to 10 percent of those who are infected.Today, people who contract tuberculosis typically take a course of drugs for six to eight months. However, the length of treatment means some patients don ’t stick with the therapy or may develop adverse effects from drug toxicity. Some may develop resistance to the d...
Source: UCLA Newsroom: Health Sciences - May 13, 2019 Category: Universities & Medical Training Source Type: news

Experimental Agent Offers First Hope for Rare Genetic Disorder Experimental Agent Offers First Hope for Rare Genetic Disorder
An experimental agent promises to improve the lives of patients with Angelman syndrome, a rare genetic disorder for which there are no approved therapies and that carries a high, unmet medical need.Medscape Medical News (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - May 13, 2019 Category: Consumer Health News Tags: Neurology & Neurosurgery News Source Type: news

Nipple reconstruction techniques could be improved with 3D scaffolds
(Mary Ann Liebert, Inc./Genetic Engineering News) Nipple and areola reconstruction is a common breast reconstruction technique, especially for breast cancer patients after mastectomy. However, tissue for grafting is a limiting factor, and there is no gold standard method. Correspondingly, researchers are continuously exploring new methods for the expansion of patient-matched tissue samples and the improvement of cosmetic outcome. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - May 13, 2019 Category: International Medicine & Public Health Source Type: news