FDA OKs Givinostat for Duchenne Muscular Dystrophy FDA OKs Givinostat for Duchenne Muscular Dystrophy
Givinostat (Duvyzat), a histone deacetylase inhibitor, is the first nonsteroidal drug approved to treat patients aged 6 years or older with all genetic variants of DMD.Medscape Medical News (Source: Medscape Neurology and Neurosurgery Headlines)
Source: Medscape Neurology and Neurosurgery Headlines - March 22, 2024 Category: Neurology Tags: Neurology & Neurosurgery Source Type: news
Tufts Medicine Study Shows Rapid Whole Genome Sequencing Highly Successful at Screening Newborns for Cancer in Children ’s Hospitals
Pathologists and clinical laboratories have an opportunity to help create newborn rWGS programs in their parent hospitals and health systems Diagnosing disease in infants is particularly difficult using typical clinical laboratory testing and modalities. Thus, the use of rapid Whole Genome Sequencing (rWGS) is gaining acceptance when such a procedure is deemed “medically appropriate” based […]
The post Tufts Medicine Study Shows Rapid Whole Genome Sequencing Highly Successful at Screening Newborns for Cancer in Children’s Hospitals appeared first on Dark Daily. (Source: Dark Daily)
Source: Dark Daily - March 22, 2024 Category: Laboratory Medicine Authors: Jillia Schlingman Tags: Laboratory News Laboratory Testing Molecular Diagnostics, Genetic Testing, Whole Gene Sequencing Precision Medicine anatomic pathology AP Associated Press carrier testing clinical laboratory clinical pathology Dark Daily dark intelli Source Type: news
Clearance for driving in genetic generalized epilepsy - Desai J, Sadrieh K, Singh E.
A key aspect of management of genetic generalized epilepsy involves assessing seizure control and deciding suitability for driving motor vehicles. We surveyed child neurologists and pediatric epileptologists on key questions that practitioners should ask p... (Source: SafetyLit)
Source: SafetyLit - March 22, 2024 Category: International Medicine & Public Health Tags: Distraction, Fatigue, Chronobiology, Vigilance, Workload Source Type: news
FDA Approves Nonsteroidal Treatment for Duchenne Muscular Dystrophy
The FDA approved Duvyzat (givinostat) oral medication for the treatment of Duchenne Muscular Dystrophy (DMD) in patients six years of age and older. Duvyzat is the first nonsteroidal drug approved to treat patients with all genetic variants of DMD. (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - March 21, 2024 Category: Drugs & Pharmacology Authors: FDA Source Type: news
Chinese patient receives first successful pig-to-human liver transplant
Semafor Signals Supported by The News Scientists have successfully transplanted a genetically engineered pig liver into a human for the first time Chinese researchers inserted the liver, which was taken from a pig that had been genetically edited to remove proteins that can cause organ rejection,…#newsscientists #wechat #newyorkuniversity #kathyguillermo #nature #scmp (Source: Reuters: Health)
Source: Reuters: Health - March 21, 2024 Category: Consumer Health News Source Type: news
A Man Has Received the First Pig-Kidney Transplant
The first reported person in the world has received a genetically modified pig kidney. A transplant surgeon at Massachusetts General Hospital successfully performed the groundbreaking, four-hour procedure on Richard Slayman, a 62-year-old manager at the Massachusetts Department of Transportation, on March 16. His doctors report he is doing well and expect him to leave the hospital soon.
The surgery was the culmination of years of work transplanting kidneys from a specially bred group of pigs—which had been genetically modified to more closely resemble those of humans—into primates. Encouraged by those result...
Source: TIME: Health - March 21, 2024 Category: Consumer Health News Authors: Alice Park Tags: Uncategorized healthscienceclimate Source Type: news
The surprising truth about inbreeding in the UK - and how the NHS says cousin marriage is NO different to women choosing to give birth in their 30s 'because both are risky'
Children resulting from a union of first-cousins or closer relations have an increased chance of inheriting a host of genetic conditions compared to the general population. (Source: the Mail online | Health)
Source: the Mail online | Health - March 21, 2024 Category: Consumer Health News Source Type: news
Pioneering pig-to-human kidney transplant performed in U.S.
A 62-year-man with end-stage renal disease has become the first human to receive a new kidney from a genetically modified pig, doctors from Massachusetts General Hospital in Boston announces. (Source: CBC | Health)
Source: CBC | Health - March 21, 2024 Category: Consumer Health News Tags: News/Health Source Type: news
RNA deserves its own massive counterpart to the human genome project, researchers argue
This report is very much modeled on the
NASEM report
that initiated the Human Genome Project,
”
completed in 2003,
says Cheung, who wasn’t involved in the new report’s drafting. But as the report notes,
“The RNome is much more complex
”
than a genome.
For one thing, frequent modifications to RNA mean there will be no fixed, reference sequence like the one researchers produced for the human genome. For a given RNA molecule, researchers will have to document
“not only the sequence, but also the type and location of the modifica...
Source: ScienceNOW - March 21, 2024 Category: Science Source Type: news
Massachusetts General succeeds with genetically edited pig kidney transplant
Massachusetts General Hospital Thursday announced the world ' s first successful genetically edited pig kidney transplant into a human. (Source: Health News - UPI.com)
Source: Health News - UPI.com - March 21, 2024 Category: Consumer Health News Source Type: news
Big news for Kidney patients: Pig kidney successfully transplanted into a living patient
In a groundbreaking procedure at Massachusetts General Hospital, doctors successfully transplanted a pig kidney into a 62-year-old patient, marking a milestone in xenotransplantation. The recipient, Richard Slayman, expressed hope for himself and others awaiting transplants. With recent advancements, including genetic modifications in pigs, this achievement offers promise for addressing the critical shortage of organs. (Source: The Economic Times)
Source: The Economic Times - March 21, 2024 Category: Consumer Health News Source Type: news
Surgeons Implant Pig Kidney Into First Living Human Patient
THURSDAY, March 21, 2024 (HealthDay news) -- For the first time ever, doctors have transplanted a genetically edited pig kidney into a human suffering from advanced kidney failure.
Such pig kidneys, altered to lower the risk of rejection and... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - March 21, 2024 Category: General Medicine Source Type: news
US Surgeons Perform First Pig-to-human Kidney Transplant US Surgeons Perform First Pig-to-human Kidney Transplant
A 62-year-man with end-stage renal disease has become the first human to receive a new kidney from a genetically modified pig, doctors from Massachusetts General Hospital in...Reuters Health Information (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 21, 2024 Category: Consumer Health News Tags: Nephrology Source Type: news
Surgeons Transplant Pig Kidney Into a Patient, a Medical Milestone
The man continues to improve, doctors said. Organs from genetically engineered pigs one day may make dialysis obsolete. (Source: NYT Health)
Source: NYT Health - March 21, 2024 Category: Consumer Health News Authors: Roni Caryn Rabin Tags: your-feed-science Kidneys Genetic Engineering Pigs Surgery and Surgeons Immune System Doctors Cloning Diabetes Black People Urine Blood Massachusetts General Hospital Boston (Mass) Source Type: news
The World ’s Most Expensive Drug Is Now a $4.25 Million Gene Therapy
A new gene therapy for an ultra-rare disease will have a wholesale cost of $4.25 million, making it the world’s most expensive drug.
The one-time treatment, Lenmeldy, won U.S. regulatory approval on Monday to correct the underlying cause of a hereditary condition called early-onset metachromatic leukodystrophy, or MLD.
MLD is a fatal disease in which infants sometimes start to lose the ability to walk and talk. Orchard Therapeutics said the drug’s price “reflects its clinical, economic and societal value” in a statement Wednesday.
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Source: TIME: Health - March 21, 2024 Category: Consumer Health News Authors: Gerry Smith/Bloomberg Tags: Uncategorized healthscienceclimate wire Source Type: news
