Could cloned pigs solve the human organ shortage?
NPR's Mary Louise Kelly talks with bioethicist and professor at Lehigh University, Michael Gusmano, about the ethics of using cloned, genetically modified pigs for human organ transplants. (Source: NPR Health and Science)
Source: NPR Health and Science - April 5, 2024 Category: Consumer Health News Authors: Jonaki Mehta Source Type: news

Puberty blockers may NOT be reversible and could raise children's risk of fertility problems and even cancer, Mayo Clinic study suggests
'We provide unprecedented histological evidence revealing detrimental pediatric testicular sex gland responses' to the drugs, geneticist Nagarajan Kannan and others wrote. (Source: the Mail online | Health)
Source: the Mail online | Health - April 5, 2024 Category: Consumer Health News Source Type: news

Clinicians Slam FDA Over Approval of Opioid Addiction Test Clinicians Slam FDA Over Approval of Opioid Addiction Test
Researchers say a test meant to measure risk for opioid use disorder may cause harm. Their arguments are part of a larger debate about using genetic information to guide clinical care.Medscape Medical News (Source: Medscape Cardiology Headlines)
Source: Medscape Cardiology Headlines - April 5, 2024 Category: Cardiology Tags: Family Medicine/Primary Care Source Type: news

Novel biological mechanism discovered that could lead to new treatments for neurological disorders, cancers
The lab of Yongchao C. Ma, PhD, at Stanley Manne Children's Research Institute at Ann & Robert H. Lurie Children's Hospital of Chicago discovered a fundamental biological mechanism that could lead to new treatments for neurological diseases, such as spinal muscular atrophy (SMA) and autism, as well as different cancers. The study was published in the journal Human Molecular Genetics. Dr. Ma's team found that chemical modification of RNA (called RNA methylation) regulates mitochondrial function. (Source: World Pharma News)
Source: World Pharma News - April 5, 2024 Category: Pharmaceuticals Tags: Featured Research Research and Development Source Type: news

Susceptibility to treatment-resistant depression within families - Cheng CM, Chen MH, Tsai SJ, Chang WH, Tsai CF, Lin WC, Bai YM, Su TP, Chen TJ, Li CT.
IMPORTANCE: Antidepressant responses and the phenotype of treatment-resistant depression (TRD) are believed to have a genetic basis. Genetic susceptibility between the TRD phenotype and other psychiatric disorders has also been established in previous gene... (Source: SafetyLit)
Source: SafetyLit - April 5, 2024 Category: International Medicine & Public Health Tags: Risk Factor Prevalence, Injury Occurrence Source Type: news

Genetic Test for Opioid Addiction Risk Should Be Withdrawn, Experts Tell FDA
(MedPage Today) -- A group of 31 physicians and researchers called on the FDA to reverse its decision about AvertD, a test that uses DNA to identify whether adults may have an elevated risk of developing opioid use disorder (OUD). In a letter... (Source: MedPage Today Psychiatry)
Source: MedPage Today Psychiatry - April 5, 2024 Category: Psychiatry Source Type: news

First pig kidney transplant patient goes home
Two weeks ago, surgeons from Massachusetts General Hospital for the first time ever transplanted a kidney from a specially genetically modified pig into a living kidney-failure patient, Rick Slayman. Researchers had earlier tested the safety and efficacy of modified pig kidneys in brain-dead…#rickslayman #egenesis #newyorkuniversity #arthurcaplan #cambridgeuniversity #roycalne #reasoncom (Source: Reuters: Health)
Source: Reuters: Health - April 4, 2024 Category: Consumer Health News Source Type: news

Boston man, 62, and the first living patient with transplanted pig kidney is discharged from hospital and 'recovering well' - and says he has the 'cleanest bill of health' he's had in years
The first patient to receive an organ transplant from a genetically modified pig, Richard Slayman, 62 [shown] has fared so well that he has been discharged from the hospital. (Source: the Mail online | Health)
Source: the Mail online | Health - April 4, 2024 Category: Consumer Health News Source Type: news

Scientists Find New Genetic Variants for Obesity
Researchers believe they have discovered a new biological mechanism for obesity, pointing to rare variants on two genes that dramatically increase the risk of carrying excess weight. Research published in the journal Nature Genetics on Thursday points to variants that raise the chance of being obese by as much as six times. Unlike other known variants that affect weight gain in children, these only appear to play a role in adults. [time-brightcove not-tgx=”true”] Unraveling obesity’s mechanisms could help scientists develop new drugs, or tailor existing ones, for a condition that now affects ...
Source: TIME: Health - April 4, 2024 Category: Consumer Health News Authors: Ashleigh Furlong/Bloomberg Tags: Uncategorized healthscienceclimate wire Source Type: news

Man who received pig kidney transplant leaves hospital, feels great
Richard Slayman, the first living person to receive a genetically edited kidney from a pig, has been discharged from hospital and is “recovering well,” doctors from the Massachusetts General Hospital said. (Source: Washington Post: To Your Health)
Source: Washington Post: To Your Health - April 4, 2024 Category: Consumer Health News Authors: Jennifer Hassan Source Type: news

Man with gene-edited pig kidney transplant discharged from hospital
Rick Slayman, the man who received the world ' s transplanted genetically edited pig kidney at Massachusetts General Hospital, is home Thursday after being discharged Wednesday. (Source: Health News - UPI.com)
Source: Health News - UPI.com - April 4, 2024 Category: Consumer Health News Source Type: news

Interaction between HTR2A rs3125 and negative life events in suicide attempts among patients with major depressive disorder: a cross-sectional study - Pang JY, Wang YP, Teng HM, He J, Luo R, Feng SM, Yue WH, Li HF.
This study aims to explore the interactions ... (Source: SafetyLit)
Source: SafetyLit - April 4, 2024 Category: International Medicine & Public Health Tags: Ergonomics, Human Factors, Anthropometrics, Physiology Source Type: news

Changing 23andMe’s corporate DNA will be difficult
The company aims to exploit its extraordinary cache of genetic data for drug discovery (Source: FT.com - Drugs and Healthcare)
Source: FT.com - Drugs and Healthcare - April 4, 2024 Category: Pharmaceuticals Source Type: news

Can 23andMe reinvent itself as a drug discovery company?
It aims to exploit its extraordinary cache of genetic data but changing corporate DNA is hard (Source: FT.com - Drugs and Healthcare)
Source: FT.com - Drugs and Healthcare - April 4, 2024 Category: Pharmaceuticals Source Type: news

First Pig Kidney Transplant Patient Discharged From Hospital
THURSDAY, April 4, 2024 -- Rick Slayman, the first person to receive a kidney transplant from a genetically modified pig, headed home Wednesday after faring so well that he was released from the hospital just two weeks after his groundbreaking... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - April 4, 2024 Category: General Medicine Source Type: news