Screening and Functional Validation of Human Birth Defects Genomic Variants (R01 Clinical Trial Not Allowed)
Funding Opportunity PAR-21-229 from the NIH Guide for Grants and Contracts. Rapid advances in genotyping and next generation sequencing technologies have led to the identification of genetic variants that are associated with a wide variety of congenital defects including structural birth defects (SBDs), intellectual developmental disabilities (IDDs) and inborn errors of metabolism (IEMs). Large quantities of genomic data collected from pediatric birth defects cohorts are available to the research community through several databases such as the Database of Genotypes and Phenotypes (dbGaP), the Gabriella Miller Kids First D...
Source: NIH Funding Opportunities (Notices, PA, RFA) - May 5, 2021 Category: Research Source Type: funding

BRAIN Initiative: Development and Validation of Novel Tools to Probe Cell-Specific and Circuit-Specific Processes in the Brain (R01 Clinical Trial Not Allowed)
Funding Opportunity RFA-MH-21-175 from the NIH Guide for Grants and Contracts. This is a reissue of RFA-MH-19-136. The purpose of this Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative is to encourage applications that will develop and validate novel tools to facilitate the detailed analysis of complex circuits and provide insights into cellular interactions that underlie brain function. The new tools and technologies should inform and/or exploit cell-type and/or circuit-level specificity. Plans for validating the utility of the tool/technology will be an essential feature of a successful ap...
Source: NIH Funding Opportunities (Notices, PA, RFA) - April 27, 2021 Category: Research Source Type: funding

Developmental Mechanisms of Human Structural Birth Defects (P01 Clinical Trial Not Allowed)
Funding Opportunity RFA-HD-22-004 from the NIH Guide for Grants and Contracts. The purpose of this funding opportunity announcement (FOA) is to support innovative, multidisciplinary, interactive, and synergistic program projects that integrate basic, translational, and clinical approaches to understanding the developmental biology and genetic basis of significant congenital human malformations. Each program project will consist of three component research projects, in addition to associated cores. At least one project must use basic research in an animal model system and at least one project must be clinical or translatio...
Source: NIH Funding Opportunities (Notices, PA, RFA) - April 19, 2021 Category: Research Source Type: funding

Comprehensive Alcohol Research Centers (P60 Clinical trial Optional)
Funding Opportunity RFA-AA-21-006 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) invites applications for Comprehensive Alcohol Research Centers using the P60 mechanism which requires a dissemination core to initiate and expand community education related to the activities of the center. The overall purpose of the NIAAA Alcohol Research Center program is to provide leadership in conducting and fostering interdisciplinary, collaborative research on a wide variety of topics relevant to the Institutes mission. These topics include, but are not limited to: the nature, etiology, geneti...
Source: NIH Funding Opportunities (Notices, PA, RFA) - April 5, 2021 Category: Research Source Type: funding

Natural History of Disorders Screenable in the Newborn Period (R01 Clinical Trial Optional)
Funding Opportunity PAR-21-115 from the NIH Guide for Grants and Contracts. This funding opportunity announcement (FOA) encourages applications that propose to develop studies that will lead to a broad understanding of the natural history of disorders that already do or could potentially benefit from early identification by newborn screening. A comprehensive understanding of the natural history of a disorder has been identified as a necessary element to facilitate appropriate interventions for infants identified by newborn screening. By defining the sequence and timing of the onset of symptoms and complications of a disor...
Source: NIH Funding Opportunities (Notices, PA, RFA) - February 8, 2021 Category: Research Source Type: funding

Limited Competition: Specific Pathogen Free Macaque Colonies (U42 Clinical Trial Not Allowed)
Funding Opportunity PAR-21-089 from the NIH Guide for Grants and Contracts. The purpose of this Funding Opportunity Announcement is to provide continuing support for specific pathogen-free (SPF) macaque colonies previously funded under the auspices of PAR-18-669 and PAR-14-066. Breeding colonies are essential to sustain appropriate macaques for research related to Human Immunodeficiency Virus (HIV)/Acquired Immunodeficiency Syndrome (AIDS). Pedigree SPF macaques are free of certain viruses, which may confound the results of HIV/AIDS-related investigations or present a risk to the personnel who care for the animals. The SP...
Source: NIH Funding Opportunities (Notices, PA, RFA) - January 8, 2021 Category: Research Source Type: funding

Notice of Change to Budget Information and Key Dates for PAR-20-027, "Genetic Architecture of Mental Disorders in Ancestrally Diverse Populations (Collaborative U01 Clinical Trial Not Allowed)"
Notice NOT-MH-21-110 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - December 21, 2020 Category: Research Source Type: funding

Notice of Special Interest (NOSI): Discovery of the Genetic Basis of Conditions Associated with Down Syndrome for the INCLUDE (INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE) Project (X01)
Notice NOT-HD-20-039 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - December 16, 2020 Category: Research Source Type: funding

Mentored Research Experiences for Genetic Counselors (R25)
Funding Opportunity PAR-21-074 from the NIH Guide for Grants and Contracts. The NIH Research Education Program (R25) supports research education activities in the mission areas of the NIH. The overarching goal of this NHGRI R25 program is to support educational activities and mentored genomic research experiences for genetic counselors. This program will provide supervised career development experiences to genetic counselors in genomic research through courses, enhance research experiences and mentoring to gain the necessary knowledge and experience to participate and lead future genomic research efforts. To accomplish th...
Source: NIH Funding Opportunities (Notices, PA, RFA) - December 9, 2020 Category: Research Source Type: funding

Early-Stage Development of Informatics Technologies for Cancer Research and Management (U01 Clinical Trial Optional)
Funding Opportunity RFA-CA-21-014 from the NIH Guide for Grants and Contracts. The goal of this FOA is to advance cancer model systems that recapitulate human immunity in the tumor microenvironment to improve the predictivity of immuno-oncology studies. Proposed research projects must focus on recapitulation of the human immune system in their proposed cancer model using human cells or tissues to regenerate and/or recapitulate the human immune system in in vivo or in vitro immuno-oncology models in a manner that matches or exceeds representation of the human immune system achieved with murine models developed using HFT. M...
Source: NIH Funding Opportunities (Notices, PA, RFA) - December 2, 2020 Category: Research Source Type: funding

NEI Institutional Mentored Physician Scientist Award (K12 Clinical Trial Optional)
Funding Opportunity PAR-21-073 from the NIH Guide for Grants and Contracts. The purpose of this Funding Opportunity Announcement (FOA) is to encourage institutions to propose creative and innovative institutional research career development programs which prepare clinically-trained vision scientists for independent research careers. This initiative is intended to expand and strengthen the community of investigators engaged in clinical research. Such an increase in the number of well-trained clinical researchers is necessary to achieve a pool of scientists with contemporary, multidisciplinary expertise able to leverage rec...
Source: NIH Funding Opportunities (Notices, PA, RFA) - December 1, 2020 Category: Research Source Type: funding

Discovery of the Genetic Basis of Childhood Cancers and of Structural Birth Defects: Gabriella Miller Kids First Pediatric Research Program (X01 Clinical Trial Not Allowed)
Funding Opportunity PAR-21-040 from the NIH Guide for Grants and Contracts. As part of the Gabriella Miller Kids First Pediatric Research Program (Kids First), the NIH invites applications to submit samples from pediatric cohorts for whole genome sequencing at a Kids First-supported sequencing center. Applicants are encouraged to propose sequencing of existing pediatric cancer cohorts to elucidate the genetic contribution to childhood cancers, or to expand the range of disorders included within the Kids First Data Resource to investigate the genetic etiology of structural birth defects. Whole genome, exome, and transcript...
Source: NIH Funding Opportunities (Notices, PA, RFA) - October 27, 2020 Category: Research Source Type: funding

From Genomic Association to Causation: A Convergent Neuroscience Approach to Linking Levels of Analysis for Understanding Neuropsychiatric Disorders (U19 Clinical Trial Optional)
Funding Opportunity RFA-MH-21-165 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) supports research to understand causal linkages across different scales (e.g., molecular, cellular, circuit, behavioral, clinical) relevant to neuropsychiatric disorders. The Convergent Neuroscience (CN) program goal is to establish theoretical models to show how specific constituent processes at one level of analysis contribute to quantifiable properties at other levels, either directly or as emergent phenomenon. Studies should incorporate four key features: (1) a premise on identifying the causal an...
Source: NIH Funding Opportunities (Notices, PA, RFA) - October 15, 2020 Category: Research Source Type: funding

New Cohorts for Environmental Exposures and Cancer Risk (CEECR) Coordinating Center (U24 Clinical Trial Not Allowed)
Funding Opportunity RFA-CA-20-050 from the NIH Guide for Grants and Contracts. Through this Funding Opportunity Announcement (FOA), the National Cancer Institute (NCI) and National Institute of Environmental Health Sciences (NIEHS) will support a Coordinating Center to facilitate coordination across the new Cohorts for Environmental Exposures and Cancer Risk (CEECR) (see UG3/UH3 phased awards supported under companion RFA-CA-20-049). The overarching goal of the CEECR is to support innovative scientific research in new prospective cohorts to address knowledge gaps between environmental exposures and cancer etiology, and th...
Source: NIH Funding Opportunities (Notices, PA, RFA) - October 14, 2020 Category: Research Source Type: funding

Notice of Change to Budget Information and Key Dates for PAR-20-027, "Genetic Architecture of Mental Disorders in Ancestrally Diverse Populations (Collaborative U01 Clinical Trial Not Allowed)"
Notice NOT-MH-21-016 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - October 14, 2020 Category: Research Source Type: funding

Notice of Change to Budget Information and Key Dates for PAR-20-026, "Genetic Architecture of Mental Disorders in Ancestrally Diverse Populations (U01 Clinical Trial Not Allowed)"
Notice NOT-MH-21-015 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - October 14, 2020 Category: Research Source Type: funding

Notice of Correction to PAR-20-225, " Avenir Award Program for Genetics or Epigenetics of Substance Use Disorders (DP1 Clinical Trial Optional)"
Notice NOT-DA-20-093 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - September 30, 2020 Category: Research Source Type: funding

Specialized Programs of Research Excellence (SPOREs) in Human Cancers for Years 2021, 2022, and 2023 (P50 Clinical Trial Required)
Funding Opportunity PAR-20-305 from the NIH Guide for Grants and Contracts. Through this funding opportunity announcement (FOA), the National Cancer Institute (NCI) invites applications for P50 Research Center Grants for Specialized Programs of Research Excellence (SPORE). The program will fund P50 SPORE grants to support state-of-the-art investigator-initiated translational research that will contribute to improved prevention, early detection, diagnosis, and treatment of an organ-specific cancer or a highly related group of cancers. For the purpose of this FOA, a group of highly related cancers are those that are derived...
Source: NIH Funding Opportunities (Notices, PA, RFA) - September 28, 2020 Category: Research Source Type: funding

Notice of Applicant Information Webinar and Frequently Asked Questions (FAQs) for Investigator-Initiated Research on Genetic Counseling Processes and Practices Request for Applications (RFAs): RFA-HG-20-048 and RFA-HG-20-049
Notice NOT-HG-20-057 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - September 1, 2020 Category: Research Source Type: funding

Maternal and Pediatrics Precision in Therapeutics Hub (MPRINT) (P30 Clinical Trial Not Allowed)
Funding Opportunity RFA-HD-21-025 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) invites applications to form the Knowledge and Research Coordination Center (KRCC) of the NICHDs Maternal and Pediatric Precision in Therapeutics (MPRINT) Hub. The MPRINT Hub will serve as a national resource for expertise in maternal and pediatric therapeutics to conduct and foster therapeutics-focused research in obstetrics, lactation, and pediatrics while enhancing inclusion of people with disabilities. By serving as a national resource, it will aggregate, present, and expand the available knowledg...
Source: NIH Funding Opportunities (Notices, PA, RFA) - August 3, 2020 Category: Research Source Type: funding

Investigator-Initiated Research on Genetic Counseling Processes and Practices (R01, Clinical Trial Optional)
Funding Opportunity RFA-HG-20-048 from the NIH Guide for Grants and Contracts. The purpose of this initiative is to support investigator-initiated research on genetic counseling processes and practices in genomic medicine. Research is needed to optimize the genetic counseling process in the context of limited resources. Grants will assess, innovate, scale, and/or research the implementation of novel genetic counseling practices to address the need for more healthcare professionals trained in genetic counseling; the uneven access to in-person genetic counseling across U.S. health care systems, and the challenges of effecti...
Source: NIH Funding Opportunities (Notices, PA, RFA) - July 30, 2020 Category: Research Source Type: funding

Investigator-Initiated Research on Genetic Counseling Processes and Practices (R21, Clinical Trial Optional)
Funding Opportunity RFA-HG-20-049 from the NIH Guide for Grants and Contracts. The purpose of this initiative is to support targeted studies on genetic counseling processes and practices in genomic medicine. Research is needed to optimize the genetic counseling process in the context of limited resources. Grants will assess, innovate, scale, and/or research the implementation of novel genetic counseling practices to address the need for more healthcare professionals trained in genetic counseling; the uneven access to in-person genetic counseling across U.S. health care systems, and the challenges of effective and efficien...
Source: NIH Funding Opportunities (Notices, PA, RFA) - July 30, 2020 Category: Research Source Type: funding

Notice of Correction to PAR-19-223, "Avenir Award Program for Genetics or Epigenetics of Substance Use Disorders (DP1 Clinical Trial Optional)"
Notice NOT-DA-20-076 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - July 29, 2020 Category: Research Source Type: funding

Notice of Correction to PAR-20-225, "Avenir Award Program for Genetics or Epigenetics of Substance Use Disorders (DP1 Clinical Trial Optional)"
Notice NOT-DA-20-075 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - July 28, 2020 Category: Research Source Type: funding

Fertility Status as a Marker for Overall Health (R01 Clinical Trial Optional)
Funding Opportunity PAR-20-281 from the NIH Guide for Grants and Contracts. The purpose of this funding opportunity (FOA) is to support research that explores the premise that fertility status can be a marker for overall health. Chronic conditions such as concer, diabetes, and obesity can impair fertility, however, less is known about the extent to which fertility status can impact or acts as a marker for overall health. Data suggest that infertility is not necessarily a unique disease of the reproductive axis but is often physiologically or genetically linked with other diseases and conditions. Recent epidemiologic studi...
Source: NIH Funding Opportunities (Notices, PA, RFA) - July 23, 2020 Category: Research Source Type: funding

Fertility Status as a Marker for Overall Health (R21 Clinical Trial Not Allowed)
Funding Opportunity PAR-20-282 from the NIH Guide for Grants and Contracts. T?he purpose of this funding opportunity announcement (FOA) is to support exploratory/developmental research that explores the premise that fertility status can be a marker for overall health. Chronic conditions such as cancer, diabetes, and obesity can impair fertility, however, less is known about the extent to which fertility status can impact or act as a marker for overall health. Data suggest that infertility is not necessarily a unique disease of the reproductive axis but is often physiologically or genetically linked with other diseases and...
Source: NIH Funding Opportunities (Notices, PA, RFA) - July 23, 2020 Category: Research Source Type: funding

Secondary Analysis and Integration of Existing Data to Elucidate the Genetic Architecture of Cancer Risk and Related Outcomes (R21 Clinical Trials Not Allowed)
Funding Opportunity PAR-20-277 from the NIH Guide for Grants and Contracts. Through this funding opportunity announcement (FOA), the National Cancer Institute (NCI) along with the National Human Genome Research Institute (NHGRI) and National Institute of Dental and Craniofacial Research (NIDCR) encourages submission of applications proposing to conduct secondary data analysis and integration of existing datasets and database resources, with the ultimate aim to elucidate the genetic architecture of cancer risk and related outcomes (e.g., risk prediction or reduction, survival, or response to treatment, etc.). The goal of t...
Source: NIH Funding Opportunities (Notices, PA, RFA) - July 22, 2020 Category: Research Source Type: funding

Secondary Analysis and Integration of Existing Data to Elucidate the Genetic Architecture of Cancer Risk and Related Outcomes (R01 Clinical Trial Not Allowed)
Funding Opportunity PAR-20-276 from the NIH Guide for Grants and Contracts. Through this funding opportunity announcement (FOA), the National Cancer Institute (NCI) along with the National Human Genome Research Institute (NHGRI) and National Institute of Dental and Craniofacial Research (NIDCR) encourages submission of applications proposing to conduct secondary data analysis and integration of existing datasets and database resources, with the ultimate aim to elucidate the genetic architecture of cancer risk and related outcomes (e.g., risk prediction or reduction, survival, or response to treatment, etc.). The goal of t...
Source: NIH Funding Opportunities (Notices, PA, RFA) - July 22, 2020 Category: Research Source Type: funding

BRAIN Initiative: Tools for Germline Gene Editing in Marmosets (U01 - Clinical Trial Not Allowed)
Funding Opportunity RFA-DA-21-006 from the NIH Guide for Grants and Contracts. The purpose of this FOA isto develop tools and technologies to conduct cientifically rigorous, ethical, efficient, and cost-effective research infrastructure that supports germline and somatic transgenic and gene editing studies in the common marmoset (Callithrix jacchus). These studies should to answer crucial scientific questions that require genetic perturbation in a non-human primate model organism with the aim of supporting BRAIN goals of understanding the brain in health an disease. (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - July 17, 2020 Category: Research Source Type: funding

Using Human Cell Animal Chimera Brains to Study HIV Latency and Pathology R01 - Clinical Trials Not Allowed
Funding Opportunity RFA-DA-21-026 from the NIH Guide for Grants and Contracts. Recent technical advancements have enabled generating human cell-mice chimeric brains by engrafting human iPSC-derived primitive neural progenitor cells and/or cord blood-derived microglial progenitor cells into neonatal mouse. In the chimeric brain, human neural progenitor cells or microglial cells differentiate, migrate, and distribute throughout the mouse brain. They are eventually functionally integrated into various brain regions. Such successes provide opportunities to define the structure, function, genetics and plasticity of functional ...
Source: NIH Funding Opportunities (Notices, PA, RFA) - July 13, 2020 Category: Research Source Type: funding

Center for Inherited Disease Research (CIDR) High Throughput Sequencing and Genotyping Resource Access (X01)
Funding Opportunity PAR-20-230 from the NIH Guide for Grants and Contracts. The Center for Inherited Disease Research (CIDR) high-throughput genotyping, sequencing and supporting statistical genetics services are designed to aid the identification of genes or genetic modifications that contribute to human health and disease or to enhance existing collections of well-phenotyped specimens by the addition of genotype or next-generation sequence data. The laboratory specializes in genomic services that cannot be efficiently carried out in individual investigator laboratories. CIDR provides the most up-to-date platforms, servi...
Source: NIH Funding Opportunities (Notices, PA, RFA) - June 11, 2020 Category: Research Source Type: funding

Emergency Awards: SARS-CoV-2 Serological Sciences Centers of Excellence (U54 Clinical Trial Optional)
Funding Opportunity RFA-CA-20-038 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) is associated with the COVID-19 Supplement funded through the Paycheck Protection Program and Health Care Enhancement Act (P.L. 116-139) which directs the National Cancer Institute of the NIH to develop, validate, improve, and implement serological testing and associated technologies . The purpose of the FOA is to establish Serological Sciences Centers of Excellence with the goal of identifying and advancing research opportunities to characterize the immune responses elicited by SARS-CoV-2 viral infec...
Source: NIH Funding Opportunities (Notices, PA, RFA) - June 5, 2020 Category: Research Source Type: funding

Emergency Awards: Research Projects in SARS-CoV-2 Serological Sciences (U01 Clinical Trial Optional)
Funding Opportunity RFA-CA-20-039 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) is associated with the COVID-19 Supplement funded through the Paycheck Protection Program and Health Care Enhancement Act (P.L. 116-139) which directs the National Cancer Institute of the NIH to develop, validate, improve, and implement serological testing and associated technologies. The purpose of the FOA is to establish Serological Sciences Research Projects with the goals of: identifying and advancing research opportunities to characterize the immune responses elicited by SARS-CoV-2 viral infectio...
Source: NIH Funding Opportunities (Notices, PA, RFA) - June 5, 2020 Category: Research Source Type: funding

Avenir Award Program for Genetics or Epigenetics of Substance Use Disorders (DP1 Clinical Trial Optional)
Funding Opportunity PAR-20-225 from the NIH Guide for Grants and Contracts. Avenir means future in French, and this award looks toward the future by supporting early stage investigators proposing highly innovative studies. The award will support those in an early stage of their career who may lack the preliminary data required for an R01 grant, but who propose high impact research and who show promise of being tomorrow's leaders in the field. NIDA has developed two Avenir Award Programs, one for HIV/AIDS research and the other for genetics or epigenetics studies. (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - June 1, 2020 Category: Research Source Type: funding

Limited Competition: National Primate Research Centers (P51) Program
Funding Opportunity PAR-20-181 from the NIH Guide for Grants and Contracts. This FOA encourages grant applications that support the activities of the National Primate Research Centers (NPRCs). Nonhuman primates (NHPs) are most closely related to humans, both physiologically and genetically. Therefore, NHPs are critical animal models for basic and translational research aimed at understanding human biology, both in normal and diseased states. Proper husbandry and management of NHPs require specialized physical and intellectual resources, which are most effectively and economically provided in centralized primate centers, t...
Source: NIH Funding Opportunities (Notices, PA, RFA) - May 4, 2020 Category: Research Source Type: funding

Polygenic Risk Score (PRS) Methods and Analysis for Populations of Diverse Ancestry Coordinating Center (U01 Clinical Trial Not Allowed)
Funding Opportunity RFA-HG-20-002 from the NIH Guide for Grants and Contracts. The goal of the intended FOA is to establish a Coordinating Center (CC) for PRS Methods and Analysis for Populations of Diverse Ancestry to provide centralized support, infrastructure, coordination, and data analysis for the program collaboratively generate and refine PRS for populations of diverse ancestry by integrating existing datasets with genomic and phenotype data for a range of complex diseases and traits. Together with PRS Centers (described in a separate FOA), grantees funded under the intended FOA will form a Consortium with the prim...
Source: NIH Funding Opportunities (Notices, PA, RFA) - March 23, 2020 Category: Research Source Type: funding

Polygenic Risk Score (PRS) Methods and Analysis for Populations of Diverse Ancestry Centers (U01 Clinical Trial Not Allowed)
Funding Opportunity RFA-HG-20-001 from the NIH Guide for Grants and Contracts. The goal of the intended FOA is to establish Centers for PRS Methods and Analysis for Populations of Diverse Ancestry to collaboratively generate and refine PRS for populations of diverse ancestry by integrating existing datasets with genomic and phenotype data for a range of complex diseases and traits. Together with a Coordinating Center (described in a separate FOA), grantees funded under the intended FOA will form a Consortium with the primary objectives of: 1) leveraging genetic diversity to develop methods and improve the applicability of...
Source: NIH Funding Opportunities (Notices, PA, RFA) - March 23, 2020 Category: Research Source Type: funding

Special Topic Research Education Course: Exploring Auditory and Vestibular Biology (R25 - Clinical Trial Not Allowed)
Funding Opportunity RFA-DC-20-001 from the NIH Guide for Grants and Contracts. The over-arching goal of this NIDCD R25 program is to support educational activities that foster a better understanding of biomedical research and its implications in the areas of auditory and vestibular research. The complexity of auditory and vestibular biology processes provide our hearing and balance function. Interruption of these processes may occur from a variety of factors, including genetic, environmental and pathogenic agents, and often results in the loss of hearing and balance function. While loss or impairment of these functions ar...
Source: NIH Funding Opportunities (Notices, PA, RFA) - March 23, 2020 Category: Research Source Type: funding

Notice of Special Interest (NOSI): Availability of Administrative Supplements for Providing Research Experiences in Genomic Research for Genetic Counselors
Notice NOT-HG-20-028 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - March 18, 2020 Category: Research Source Type: funding

Research Projects to Enhance Applicability of Mammalian Models for Translational Research (R01 Clinical Trial Not Allowed)
Funding Opportunity PAR-20-131 from the NIH Guide for Grants and Contracts. The purpose of this Funding Opportunity Announcement (FOA) is to invite applications for projects to expand, improve, or transform the utility of mammalian cancer and tumor models for translational research. With this FOA, the NCI intends to encourage submission of projects devoted to demonstrating that mammalian models or their derivatives used for translational research are robust representations of human biology, are appropriate to test questions of clinical importance, and provide reliable information for patients' benefit. These practical goa...
Source: NIH Funding Opportunities (Notices, PA, RFA) - March 12, 2020 Category: Research Source Type: funding

In-Depth Phenotyping and Research Using IMPC-Generated Knockout Mouse Strains Exhibiting Embryonic or Perinatal Lethality or Subviability (R01 Clinical Trial Not Allowed)
Funding Opportunity PAR-20-137 from the NIH Guide for Grants and Contracts. The purpose of this Funding Opportunity Announcement (FOA) is to encourage applications to phenotype and/or perform research on embryonic lethal knockout (KO) mouse strains being generated through the International Mouse Phenotyping Consortium (IMPC) of which the NIH Knockout Mouse Phenotyping Program (KOMP2) is a member. The mission of IMPC is to generate a comprehensive catalogue of mammalian gene function that will provide the foundation for functional analyses of human genetic variation. As of November 2019, the IMPC-KOMP2 KO mouse phenotyping...
Source: NIH Funding Opportunities (Notices, PA, RFA) - March 12, 2020 Category: Research Source Type: funding

Notice of Special Interest (NOSI): Human Molecular Genetics of Substance Use Disorders
Notice NOT-DA-20-030 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - March 5, 2020 Category: Research Source Type: funding

Network for Identification, Evaluation, and Tracking of Older Persons with Superior Cognitive Performance for Their Chronological Age (U19 Clinical Trial Not Allowed)
Funding Opportunity RFA-AG-21-015 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) invites applications to establish a network to identify, evaluate, track, and conduct research across multiple sites on older adults with superior cognitive performance for their age ("cognitive super agers"). The activity would support aggregation of sufficient numbers of these individuals to advance the fields understanding of factors that promote sustained cognitive health and those that are not of primary importance. Uniform identification and uniform data collection will allow the study...
Source: NIH Funding Opportunities (Notices, PA, RFA) - February 18, 2020 Category: Research Source Type: funding

National Institute on Aging Genetics of Alzheimer's Disease Data Storage Site (U24 Clinical Trial Not Allowed)
Funding Opportunity PAR-20-110 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) invites applications specific to infrastructure that will support the storage, analysis, and sharing of primary and secondary data for the genetics and genomics of Alzheimer's disease and Alzheimer's disease-related dementias (AD/ADRD). (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - February 7, 2020 Category: Research Source Type: funding

Harmonization of Alzheimers Disease and Related Dementias (AD/ADRD) Genetic, Epidemiologic, and Clinical Data to Enhance Therapeutic Target Discovery (U24 Clinical Trial Not Allowed)
Funding Opportunity PAR-20-099 from the NIH Guide for Grants and Contracts. The National Institute on Aging (NIA) invites applications specific to infrastructure that will support, under a single cooperative agreement (U24), phenotypic data harmonization on subjects with Alzheimer's Disease Sequencing Project (ADSP) genetic and genomic data. These data will become a long-lived legacy data set that will be perpetually curated. The FOA will fund a single vanguard network of researchers with expertise in genetics, epidemiology, and clinical specialties who will work with the ADSP and with study cohort leads on data harmoniza...
Source: NIH Funding Opportunities (Notices, PA, RFA) - January 23, 2020 Category: Research Source Type: funding

KUH Predoctoral to Postdoctoral Fellow Transition Award (F99/K00)
Funding Opportunity RFA-DK-19-032 from the NIH Guide for Grants and Contracts. The purpose of the Kidney, Urology or Hematology (KUH) Predoctoral to Postdoctoral Fellow Transition Awards (F99/K00) is to recruit exceptional graduate students from diverse research fields to pursue postdoctoral training focused on Kidney, Urology or Hematology (K, U, or H) research. Talented graduate students from disciplines including, but not limited to, engineering, statistics, data science, imaging, biochemistry and genetics are invited to apply to this opportunity. Graduate students who are already involved in K, U, or H research are no...
Source: NIH Funding Opportunities (Notices, PA, RFA) - January 16, 2020 Category: Research Source Type: funding

KUH Predoctoral to Postdoctoral Fellow Transition Award (F99/K00)
The purpose of the Kidney, Urology or Hematology (KUH) Predoctoral to Postdoctoral Fellow Transition Awards (F99/K00) is to recruit exceptional graduate students from diverse research fields to pursue postdoctoral training focused on Kidney, Urology or Hematology (K, U, or H) research. Talented graduate students from disciplines including, but not limited to, engineering, statistics, data science, imaging, biochemistry and genetics are invited to apply to this opportunity. Graduate students who are already involved in K, U, or H research are not eligible for the F99/K00 award and are instead encouraged to apply for the Rut...
Source: NIDDK Funding Opportunities - January 16, 2020 Category: Endocrinology Source Type: funding

Notice of Special Interest: Development of Statistical, Population Genetics and Computational Methods Related to Polygenic Prediction of Health and Disease in Diverse Populations
Notice NOT-HG-20-010 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - January 13, 2020 Category: Research Source Type: funding

Mendelian Genomics Research Centers (U01 Clinical Trial Optional)
Funding Opportunity RFA-HG-20-007 from the NIH Guide for Grants and Contracts. The purpose of this Funding Opportunity is to establish a consortium aimed at significantly increasing the proportion of Mendelian conditions with an identified genetic cause. A key objective of the Mendelian Genomics Research Centers is to develop and apply approaches to discover causal genes underlying Mendelian conditions for which a candidate gene was not identified using whole exome sequencing alone. (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - January 13, 2020 Category: Research Source Type: funding

Pilot Centers for Precision Disease Modeling (U54)(Clinical Trials Not Allowed)
Funding Opportunity PAR-20-085 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) invites U54 cooperative agreement applications for Pilot Centers for Precision Disease Modeling. The goal of the Centers is to support collaborative research projects that link current personalized medicine efforts in human subjects with advances in animal genomics and technologies for genetic manipulation and creation of interspecies somatic hybrids. Functionally linking these areas of research will produce programs to enhance the predictive value of preclinical studies based on the use of precision ani...
Source: NIH Funding Opportunities (Notices, PA, RFA) - January 8, 2020 Category: Research Source Type: funding