Limited Competition: Renewal of the Caenorhabditis Intervention Testing Program (U01 Clinical Trial Not Allowed)
Funding Opportunity RFA-AG-22-029 from the NIH Guide for Grants and Contracts. The purpose of the Caenorhabditis Interventions Testing Program (CITP) is to test, under standardized conditions at a consortium of three sites, potential intervention strategies that may moderate/alleviate health declines associated with aging across genetically diverse species and strains of Caenorhabditis. (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - September 23, 2021 Category: Research Source Type: funding

Notice of Change to Research Strategy Section Page Limits for RFA-DK-21-502, Limited Competition for the Data Coordinating Center (DCC) for the NIDDK Inflammatory Bowel Disease Genetics Consortium (IBDGC) (U24 Clinical Trial Optional)
Notice NOT-DK-21-028 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - September 22, 2021 Category: Research Source Type: funding

Limited Competition:Caenorhabditis Intervention Testing Program Data Coordinating Center (U24 Clinical Trial Not Allowed)
Funding Opportunity RFA-AG-22-028 from the NIH Guide for Grants and Contracts. The purpose of this Funding Opportunity Announcement (FOA) is to maintain the Data Coordinating Center (DCC) for the Caenorhabditis Intervention Testing Program (CITP,) to coordinate data collection and analysis among the laboratories participating in the CITP, and to provide public access to standard operating procedures and experimental outcomes (including an accessible, annotated, and user-friendly database). The purpose of the CITP is to test, under standardized conditions at a consortium of three sites, potential intervention strategies th...
Source: NIH Funding Opportunities (Notices, PA, RFA) - September 21, 2021 Category: Research Source Type: funding

Pancreatic Cancer Detection Consortium: Management and Data Coordination Unit (U24 Clinical Trial Not Allowed)
Funding Opportunity PAR-21-335 from the NIH Guide for Grants and Contracts. The purpose of this Funding Opportunity Announcement (FOA) is to solicit applications for the Research Units (RUs), one of the two scientific components of the Pancreatic Cancer Detection Consortium (PCDC), to conduct research on early detection of pancreatic ductal adenocarcinoma (PDAC) and characterization of its precursor lesions to identify those patients who are at high risk of progression to cancer. The PCDC will continue to address one of the four research priorities identified in the National Cancer Institute's 2014 Scientific Framework fo...
Source: NIH Funding Opportunities (Notices, PA, RFA) - September 16, 2021 Category: Research Source Type: funding

Pancreatic Cancer Detection Consortium: Research Units (U01 Clinical Trial Optional)
Funding Opportunity PAR-21-334 from the NIH Guide for Grants and Contracts. The purpose of this Funding Opportunity Announcement (FOA) is to solicit applications for the Research Units (RUs), one of the two scientific components of the Pancreatic Cancer Detection Consortium (PCDC), to conduct research on early detection of pancreatic ductal adenocarcinoma (PDAC) and characterization of its precursor lesions to identify those patients who are at high risk of progression to cancer. The PCDC will continue to address one of the four research priorities identified in the National Cancer Institute's 2014 Scientific Framework fo...
Source: NIH Funding Opportunities (Notices, PA, RFA) - September 16, 2021 Category: Research Source Type: funding

Utilizing the PLCO Biospecimens Resource to Bridge Gaps in Cancer Etiology and Early Detection Research (U01 Clinical Trial Not Allowed)
Funding Opportunity PAR-21-330 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) encourages the submission of applications that propose to advance research in cancer etiology and early detection biomarkers, utilizing the advantages of the unique biorepository resources of the NCI-sponsored Prostate, Lung, Colorectal, and Ovarian Cancer (PLCO) Screening Trial. The PLCO Biorepository offers high-quality, prospectively collected, serial pre-diagnostic blood samples from the PLCO screened arm participants, and a onetime collection of buccal cells from the control arm participants. Availa...
Source: NIH Funding Opportunities (Notices, PA, RFA) - September 8, 2021 Category: Research Source Type: funding

Basic Research in Cancer Health Disparities (R01 Clinical Trial Not Allowed)
Funding Opportunity PAR-21-322 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) encourages grant applications from investigators interested in conducting basic, mechanistic research into the biological/genetic causes of cancer health disparities. These research project grants will support innovative studies designed to investigate biological/genetic bases of cancer disparities, such as (1) mechanistic studies of biological factors associated with cancer disparities, including those related to basic research in cancer biology or cancer prevention strategies, (2) the development and t...
Source: NIH Funding Opportunities (Notices, PA, RFA) - September 2, 2021 Category: Research Source Type: funding

Basic Research in Cancer Health Disparities (R21 Clinical Trial Not Allowed)
Funding Opportunity PAR-21-323 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) encourages grant applications from investigators interested in conducting basic, mechanistic research into the biological/genetic causes of cancer health disparities. These research project grants will support innovative studies designed to investigate biological/genetic bases of cancer health disparities, such as (1) mechanistic studies of biological factors associated with cancer health disparities, including those related to basic research in cancer biology or cancer prevention strategies, (2) the dev...
Source: NIH Funding Opportunities (Notices, PA, RFA) - September 2, 2021 Category: Research Source Type: funding

Basic Research in Cancer Health Disparities (R03 Clinical Trial Not Allowed)
Funding Opportunity PAR-21-324 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) encourages grant applications from investigators interested in conducting basic, mechanistic research into the biological/genetic causes of cancer health disparities. These research project grants will support innovative studies designed to investigate biological/genetic bases of cancer health disparities, such as (1) mechanistic studies of biological factors associated with cancer disparities, including those related to basic research in cancer biology or cancer prevention strategies, (2) the developmen...
Source: NIH Funding Opportunities (Notices, PA, RFA) - September 2, 2021 Category: Research Source Type: funding

Limited Competition for the Data Coordinating Center (DCC) for the NIDDK Inflammatory Bowel Disease Genetics Consortium (IBDGC) (U24 Clinical Trial Optional)
Funding Opportunity RFA-DK-21-502 from the NIH Guide for Grants and Contracts. The NIDDK Inflammatory Bowel Disease Genetics Consortium (IBDGC) was established in July 2002 for the purpose of identifying genetic variation predisposing to Inflammatory Bowel Disease (IBD). Since its establishment and in collaboration with the International IBD Genetics Consortium, the NIDDK IBDGC has identified over 250 IBD susceptibility loci. However, for the great majority of these loci, the specific causal variants and effector genes have not yet been identified, and the biological mechanisms through which these variants influence IBD p...
Source: NIH Funding Opportunities (Notices, PA, RFA) - September 2, 2021 Category: Research Source Type: funding

NIDDK Inflammatory Bowel Disease Genetics Consortium (IBDGC) Genetic Research Centers (GRCs) (U01 Clinical Trial Optional)
Funding Opportunity RFA-DK-21-022 from the NIH Guide for Grants and Contracts. The NIDDK Inflammatory Bowel Disease Genetics Consortium (IBDGC) was established in July 2002 for the purpose of identifying genetic variation predisposing to Inflammatory Bowel Disease (IBD). Since its establishment and in collaboration with the International IBD Genetics Consortium, the NIDDK IBDGC has identified over 250 IBD susceptibility loci. However, for the great majority of these loci, the specific causal variants and effector genes have not yet been identified, and the biological mechanisms through which these variants influence IBD p...
Source: NIH Funding Opportunities (Notices, PA, RFA) - September 1, 2021 Category: Research Source Type: funding

Limited Competition: Continued Development of the Gabriella Miller Kids First Pediatric Data Resource Center (U2C Clinical Trial Not Allowed)
Funding Opportunity RFA-RM-21-014 from the NIH Guide for Grants and Contracts. This limited competition Funding Opportunity Announcement (FOA) solicits applications for the continued development of the Gabriella Miller Kids First Pediatric Data Resource Center (DRC), which consists of the following components: a Data Resource Core, a Data Coordination Core, and an Administrative and Outreach Core. The goal of the cloud-based Data Resource is to accelerate discovery of genetic etiology and shared biologic pathways within and across childhood cancers and structural birth defects by facilitating access to and querying of ann...
Source: NIH Funding Opportunities (Notices, PA, RFA) - August 24, 2021 Category: Research Source Type: funding

Limited Competition for the Continuation of Epidemiology of Diabetes Interventions and Complications (EDIC) Study Research Center (Collaborative U01 Clinical Trial Not Allowed)
Funding Opportunity RFA-DK-21-503 from the NIH Guide for Grants and Contracts. The purpose of this Funding Opportunity Announcement (FOA) is to continue to follow the Epidemiology of Diabetes Interventions and Complications (EDIC) cohort through a collaborative cooperative agreement. EDIC is an observational study that was launched at the completion of the Diabetes Control and Complications Trial (DCCT) trial. The DCCT showed that intensive therapy significantly reduced the risk of diabetes complications compared to conventional therapy. At DCCT completion, all cohort members were taught intensive diabetes therapy. In 199...
Source: NIH Funding Opportunities (Notices, PA, RFA) - August 17, 2021 Category: Research Source Type: funding

CCRP Initiative: Chemical Threat Agent-induced Pulmonary and Ocular Pathophysiological Mechanisms (R01 Clinical Trial Not Allowed)
Funding Opportunity RFA-ES-21-006 from the NIH Guide for Grants and Contracts. The purpose of this Funding Opportunity Announcement (FOA) is to support research seeking to understand mechanisms of chemical toxicity and to identify potential molecular/genetic targets that reduce acute effects of chemical threat agents that affect the eyes and lungs. These discoveries can lead to exploration of therapeutic countermeasures through early stage development efforts supported by the Countermeasures Against Chemical Threats (CounterACT) NIH-wide program, a component within the Chemical Countermeasures Research Program (CCRP). (So...
Source: NIH Funding Opportunities (Notices, PA, RFA) - June 25, 2021 Category: Research Source Type: funding

India Collaborative Vision Research Program (R01 Clinical Trial Not Allowed)
Funding Opportunity PAR-21-249 from the NIH Guide for Grants and Contracts. This funding Opportunity Announcement (FOA) encourages Multiple Principal Investigator (Multi-PD/PI) applications from United States (U.S.) and Indian institution as bilateral collaborations that will advance science and technology important to understanding, preventing, and treating blinding eye diseases, visual disorders, and their complications. Areas of Research Collaboration: Applications are encouraged from organization/institutions that propose to conduct research on the basic biology and/or genetics of ophthalmic diseases through collabora...
Source: NIH Funding Opportunities (Notices, PA, RFA) - June 25, 2021 Category: Research Source Type: funding

Notice of Special Interest: Genetics of Alcohol Sensitivity and Tolerance
Notice NOT-AA-21-029 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - June 25, 2021 Category: Research Source Type: funding

NIDA Animal Genomics Program (U01 Clinical Trial Not Allowed)
Funding Opportunity PAR-21-244 from the NIH Guide for Grants and Contracts. The purpose of the NIDA Animal Genetics Program is to identify genetic, genomic, and molecular (epi)genetic variants that underlie: 1. Phenotypes associated with addictive behaviors and/or vulnerability to distinct stages along the substance use disorder (SUD) trajectory (e.g. initial/acute use, escalation of use, acquisition of tolerance, dependence, uncontrolled use, abstinence and relapse or recovery); 2. Behaviors associated with SUD (e.g. impulsivity, novelty seeking, delayed discounting, and other genetically-associated phenotypes); and 3. C...
Source: NIH Funding Opportunities (Notices, PA, RFA) - June 10, 2021 Category: Research Source Type: funding

BRAIN Initiative: Optimization of Transformative Technologies for Recording and Modulation in the Nervous System (U01 Clinical Trials Not Allowed)
Funding Opportunity RFA-NS-21-027 from the NIH Guide for Grants and Contracts. Reissue of RFA-NS-18-019: Understanding the dynamic activity of neural circuits is central to the NIH BRAIN Initiative. The invention, proof-of-concept investigation, and optimization of new technologies through iterative feedback from end users are key components of the BRAIN Initiative. This FOA seeks applications to optimize existing or emerging technologies through iterative testing with end users. The technologies and approaches should have potential to address major challenges associated with recording and modulation (including various mo...
Source: NIH Funding Opportunities (Notices, PA, RFA) - June 8, 2021 Category: Research Source Type: funding

BRAIN Initiative: New Technologies and Novel Approaches for Recording and Modulation in the Nervous System (R01 Clinical Trial Not Allowed)
Funding Opportunity RFA-NS-21-026 from the NIH Guide for Grants and Contracts. Reissue of RFA-NS-18-020: Understanding the dynamic activity of brain circuits is central to the NIH BRAIN Initiative. This FOA seeks applications for proof-of-concept testing and development of new technologies and novel approaches for recording and modulation (including various modalities for stimulation/activation, inhibition and manipulation) of cells (i.e., neuronal and non-neuronal) and networks to enable transformative understanding of dynamic signaling in the central nervous system (CNS). This FOA seeks exceptionally creative approaches...
Source: NIH Funding Opportunities (Notices, PA, RFA) - June 8, 2021 Category: Research Source Type: funding

Screening and Functional Validation of Human Birth Defects Genomic Variants (R01 Clinical Trial Not Allowed)
Funding Opportunity PAR-21-229 from the NIH Guide for Grants and Contracts. Rapid advances in genotyping and next generation sequencing technologies have led to the identification of genetic variants that are associated with a wide variety of congenital defects including structural birth defects (SBDs), intellectual developmental disabilities (IDDs) and inborn errors of metabolism (IEMs). Large quantities of genomic data collected from pediatric birth defects cohorts are available to the research community through several databases such as the Database of Genotypes and Phenotypes (dbGaP), the Gabriella Miller Kids First D...
Source: NIH Funding Opportunities (Notices, PA, RFA) - May 5, 2021 Category: Research Source Type: funding

BRAIN Initiative: Development and Validation of Novel Tools to Probe Cell-Specific and Circuit-Specific Processes in the Brain (R01 Clinical Trial Not Allowed)
Funding Opportunity RFA-MH-21-175 from the NIH Guide for Grants and Contracts. This is a reissue of RFA-MH-19-136. The purpose of this Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative is to encourage applications that will develop and validate novel tools to facilitate the detailed analysis of complex circuits and provide insights into cellular interactions that underlie brain function. The new tools and technologies should inform and/or exploit cell-type and/or circuit-level specificity. Plans for validating the utility of the tool/technology will be an essential feature of a successful ap...
Source: NIH Funding Opportunities (Notices, PA, RFA) - April 27, 2021 Category: Research Source Type: funding

Developmental Mechanisms of Human Structural Birth Defects (P01 Clinical Trial Not Allowed)
Funding Opportunity RFA-HD-22-004 from the NIH Guide for Grants and Contracts. The purpose of this funding opportunity announcement (FOA) is to support innovative, multidisciplinary, interactive, and synergistic program projects that integrate basic, translational, and clinical approaches to understanding the developmental biology and genetic basis of significant congenital human malformations. Each program project will consist of three component research projects, in addition to associated cores. At least one project must use basic research in an animal model system and at least one project must be clinical or translatio...
Source: NIH Funding Opportunities (Notices, PA, RFA) - April 19, 2021 Category: Research Source Type: funding

Comprehensive Alcohol Research Centers (P60 Clinical trial Optional)
Funding Opportunity RFA-AA-21-006 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) invites applications for Comprehensive Alcohol Research Centers using the P60 mechanism which requires a dissemination core to initiate and expand community education related to the activities of the center. The overall purpose of the NIAAA Alcohol Research Center program is to provide leadership in conducting and fostering interdisciplinary, collaborative research on a wide variety of topics relevant to the Institutes mission. These topics include, but are not limited to: the nature, etiology, geneti...
Source: NIH Funding Opportunities (Notices, PA, RFA) - April 5, 2021 Category: Research Source Type: funding

Natural History of Disorders Screenable in the Newborn Period (R01 Clinical Trial Optional)
Funding Opportunity PAR-21-115 from the NIH Guide for Grants and Contracts. This funding opportunity announcement (FOA) encourages applications that propose to develop studies that will lead to a broad understanding of the natural history of disorders that already do or could potentially benefit from early identification by newborn screening. A comprehensive understanding of the natural history of a disorder has been identified as a necessary element to facilitate appropriate interventions for infants identified by newborn screening. By defining the sequence and timing of the onset of symptoms and complications of a disor...
Source: NIH Funding Opportunities (Notices, PA, RFA) - February 8, 2021 Category: Research Source Type: funding

Limited Competition: Specific Pathogen Free Macaque Colonies (U42 Clinical Trial Not Allowed)
Funding Opportunity PAR-21-089 from the NIH Guide for Grants and Contracts. The purpose of this Funding Opportunity Announcement is to provide continuing support for specific pathogen-free (SPF) macaque colonies previously funded under the auspices of PAR-18-669 and PAR-14-066. Breeding colonies are essential to sustain appropriate macaques for research related to Human Immunodeficiency Virus (HIV)/Acquired Immunodeficiency Syndrome (AIDS). Pedigree SPF macaques are free of certain viruses, which may confound the results of HIV/AIDS-related investigations or present a risk to the personnel who care for the animals. The SP...
Source: NIH Funding Opportunities (Notices, PA, RFA) - January 8, 2021 Category: Research Source Type: funding

Notice of Change to Budget Information and Key Dates for PAR-20-027, "Genetic Architecture of Mental Disorders in Ancestrally Diverse Populations (Collaborative U01 Clinical Trial Not Allowed)"
Notice NOT-MH-21-110 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - December 21, 2020 Category: Research Source Type: funding

Notice of Special Interest (NOSI): Discovery of the Genetic Basis of Conditions Associated with Down Syndrome for the INCLUDE (INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE) Project (X01)
Notice NOT-HD-20-039 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - December 16, 2020 Category: Research Source Type: funding

Mentored Research Experiences for Genetic Counselors (R25)
Funding Opportunity PAR-21-074 from the NIH Guide for Grants and Contracts. The NIH Research Education Program (R25) supports research education activities in the mission areas of the NIH. The overarching goal of this NHGRI R25 program is to support educational activities and mentored genomic research experiences for genetic counselors. This program will provide supervised career development experiences to genetic counselors in genomic research through courses, enhance research experiences and mentoring to gain the necessary knowledge and experience to participate and lead future genomic research efforts. To accomplish th...
Source: NIH Funding Opportunities (Notices, PA, RFA) - December 9, 2020 Category: Research Source Type: funding

Early-Stage Development of Informatics Technologies for Cancer Research and Management (U01 Clinical Trial Optional)
Funding Opportunity RFA-CA-21-014 from the NIH Guide for Grants and Contracts. The goal of this FOA is to advance cancer model systems that recapitulate human immunity in the tumor microenvironment to improve the predictivity of immuno-oncology studies. Proposed research projects must focus on recapitulation of the human immune system in their proposed cancer model using human cells or tissues to regenerate and/or recapitulate the human immune system in in vivo or in vitro immuno-oncology models in a manner that matches or exceeds representation of the human immune system achieved with murine models developed using HFT. M...
Source: NIH Funding Opportunities (Notices, PA, RFA) - December 2, 2020 Category: Research Source Type: funding

NEI Institutional Mentored Physician Scientist Award (K12 Clinical Trial Optional)
Funding Opportunity PAR-21-073 from the NIH Guide for Grants and Contracts. The purpose of this Funding Opportunity Announcement (FOA) is to encourage institutions to propose creative and innovative institutional research career development programs which prepare clinically-trained vision scientists for independent research careers. This initiative is intended to expand and strengthen the community of investigators engaged in clinical research. Such an increase in the number of well-trained clinical researchers is necessary to achieve a pool of scientists with contemporary, multidisciplinary expertise able to leverage rec...
Source: NIH Funding Opportunities (Notices, PA, RFA) - December 1, 2020 Category: Research Source Type: funding

Discovery of the Genetic Basis of Childhood Cancers and of Structural Birth Defects: Gabriella Miller Kids First Pediatric Research Program (X01 Clinical Trial Not Allowed)
Funding Opportunity PAR-21-040 from the NIH Guide for Grants and Contracts. As part of the Gabriella Miller Kids First Pediatric Research Program (Kids First), the NIH invites applications to submit samples from pediatric cohorts for whole genome sequencing at a Kids First-supported sequencing center. Applicants are encouraged to propose sequencing of existing pediatric cancer cohorts to elucidate the genetic contribution to childhood cancers, or to expand the range of disorders included within the Kids First Data Resource to investigate the genetic etiology of structural birth defects. Whole genome, exome, and transcript...
Source: NIH Funding Opportunities (Notices, PA, RFA) - October 27, 2020 Category: Research Source Type: funding

From Genomic Association to Causation: A Convergent Neuroscience Approach to Linking Levels of Analysis for Understanding Neuropsychiatric Disorders (U19 Clinical Trial Optional)
Funding Opportunity RFA-MH-21-165 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) supports research to understand causal linkages across different scales (e.g., molecular, cellular, circuit, behavioral, clinical) relevant to neuropsychiatric disorders. The Convergent Neuroscience (CN) program goal is to establish theoretical models to show how specific constituent processes at one level of analysis contribute to quantifiable properties at other levels, either directly or as emergent phenomenon. Studies should incorporate four key features: (1) a premise on identifying the causal an...
Source: NIH Funding Opportunities (Notices, PA, RFA) - October 15, 2020 Category: Research Source Type: funding

New Cohorts for Environmental Exposures and Cancer Risk (CEECR) Coordinating Center (U24 Clinical Trial Not Allowed)
Funding Opportunity RFA-CA-20-050 from the NIH Guide for Grants and Contracts. Through this Funding Opportunity Announcement (FOA), the National Cancer Institute (NCI) and National Institute of Environmental Health Sciences (NIEHS) will support a Coordinating Center to facilitate coordination across the new Cohorts for Environmental Exposures and Cancer Risk (CEECR) (see UG3/UH3 phased awards supported under companion RFA-CA-20-049). The overarching goal of the CEECR is to support innovative scientific research in new prospective cohorts to address knowledge gaps between environmental exposures and cancer etiology, and th...
Source: NIH Funding Opportunities (Notices, PA, RFA) - October 14, 2020 Category: Research Source Type: funding

Notice of Change to Budget Information and Key Dates for PAR-20-027, "Genetic Architecture of Mental Disorders in Ancestrally Diverse Populations (Collaborative U01 Clinical Trial Not Allowed)"
Notice NOT-MH-21-016 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - October 14, 2020 Category: Research Source Type: funding

Notice of Change to Budget Information and Key Dates for PAR-20-026, "Genetic Architecture of Mental Disorders in Ancestrally Diverse Populations (U01 Clinical Trial Not Allowed)"
Notice NOT-MH-21-015 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - October 14, 2020 Category: Research Source Type: funding

Notice of Correction to PAR-20-225, " Avenir Award Program for Genetics or Epigenetics of Substance Use Disorders (DP1 Clinical Trial Optional)"
Notice NOT-DA-20-093 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - September 30, 2020 Category: Research Source Type: funding

Specialized Programs of Research Excellence (SPOREs) in Human Cancers for Years 2021, 2022, and 2023 (P50 Clinical Trial Required)
Funding Opportunity PAR-20-305 from the NIH Guide for Grants and Contracts. Through this funding opportunity announcement (FOA), the National Cancer Institute (NCI) invites applications for P50 Research Center Grants for Specialized Programs of Research Excellence (SPORE). The program will fund P50 SPORE grants to support state-of-the-art investigator-initiated translational research that will contribute to improved prevention, early detection, diagnosis, and treatment of an organ-specific cancer or a highly related group of cancers. For the purpose of this FOA, a group of highly related cancers are those that are derived...
Source: NIH Funding Opportunities (Notices, PA, RFA) - September 28, 2020 Category: Research Source Type: funding

Notice of Applicant Information Webinar and Frequently Asked Questions (FAQs) for Investigator-Initiated Research on Genetic Counseling Processes and Practices Request for Applications (RFAs): RFA-HG-20-048 and RFA-HG-20-049
Notice NOT-HG-20-057 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - September 1, 2020 Category: Research Source Type: funding

Maternal and Pediatrics Precision in Therapeutics Hub (MPRINT) (P30 Clinical Trial Not Allowed)
Funding Opportunity RFA-HD-21-025 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) invites applications to form the Knowledge and Research Coordination Center (KRCC) of the NICHDs Maternal and Pediatric Precision in Therapeutics (MPRINT) Hub. The MPRINT Hub will serve as a national resource for expertise in maternal and pediatric therapeutics to conduct and foster therapeutics-focused research in obstetrics, lactation, and pediatrics while enhancing inclusion of people with disabilities. By serving as a national resource, it will aggregate, present, and expand the available knowledg...
Source: NIH Funding Opportunities (Notices, PA, RFA) - August 3, 2020 Category: Research Source Type: funding

Investigator-Initiated Research on Genetic Counseling Processes and Practices (R01, Clinical Trial Optional)
Funding Opportunity RFA-HG-20-048 from the NIH Guide for Grants and Contracts. The purpose of this initiative is to support investigator-initiated research on genetic counseling processes and practices in genomic medicine. Research is needed to optimize the genetic counseling process in the context of limited resources. Grants will assess, innovate, scale, and/or research the implementation of novel genetic counseling practices to address the need for more healthcare professionals trained in genetic counseling; the uneven access to in-person genetic counseling across U.S. health care systems, and the challenges of effecti...
Source: NIH Funding Opportunities (Notices, PA, RFA) - July 30, 2020 Category: Research Source Type: funding

Investigator-Initiated Research on Genetic Counseling Processes and Practices (R21, Clinical Trial Optional)
Funding Opportunity RFA-HG-20-049 from the NIH Guide for Grants and Contracts. The purpose of this initiative is to support targeted studies on genetic counseling processes and practices in genomic medicine. Research is needed to optimize the genetic counseling process in the context of limited resources. Grants will assess, innovate, scale, and/or research the implementation of novel genetic counseling practices to address the need for more healthcare professionals trained in genetic counseling; the uneven access to in-person genetic counseling across U.S. health care systems, and the challenges of effective and efficien...
Source: NIH Funding Opportunities (Notices, PA, RFA) - July 30, 2020 Category: Research Source Type: funding

Notice of Correction to PAR-19-223, "Avenir Award Program for Genetics or Epigenetics of Substance Use Disorders (DP1 Clinical Trial Optional)"
Notice NOT-DA-20-076 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - July 29, 2020 Category: Research Source Type: funding

Notice of Correction to PAR-20-225, "Avenir Award Program for Genetics or Epigenetics of Substance Use Disorders (DP1 Clinical Trial Optional)"
Notice NOT-DA-20-075 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - July 28, 2020 Category: Research Source Type: funding

Fertility Status as a Marker for Overall Health (R01 Clinical Trial Optional)
Funding Opportunity PAR-20-281 from the NIH Guide for Grants and Contracts. The purpose of this funding opportunity (FOA) is to support research that explores the premise that fertility status can be a marker for overall health. Chronic conditions such as concer, diabetes, and obesity can impair fertility, however, less is known about the extent to which fertility status can impact or acts as a marker for overall health. Data suggest that infertility is not necessarily a unique disease of the reproductive axis but is often physiologically or genetically linked with other diseases and conditions. Recent epidemiologic studi...
Source: NIH Funding Opportunities (Notices, PA, RFA) - July 23, 2020 Category: Research Source Type: funding

Fertility Status as a Marker for Overall Health (R21 Clinical Trial Not Allowed)
Funding Opportunity PAR-20-282 from the NIH Guide for Grants and Contracts. T?he purpose of this funding opportunity announcement (FOA) is to support exploratory/developmental research that explores the premise that fertility status can be a marker for overall health. Chronic conditions such as cancer, diabetes, and obesity can impair fertility, however, less is known about the extent to which fertility status can impact or act as a marker for overall health. Data suggest that infertility is not necessarily a unique disease of the reproductive axis but is often physiologically or genetically linked with other diseases and...
Source: NIH Funding Opportunities (Notices, PA, RFA) - July 23, 2020 Category: Research Source Type: funding

Secondary Analysis and Integration of Existing Data to Elucidate the Genetic Architecture of Cancer Risk and Related Outcomes (R21 Clinical Trials Not Allowed)
Funding Opportunity PAR-20-277 from the NIH Guide for Grants and Contracts. Through this funding opportunity announcement (FOA), the National Cancer Institute (NCI) along with the National Human Genome Research Institute (NHGRI) and National Institute of Dental and Craniofacial Research (NIDCR) encourages submission of applications proposing to conduct secondary data analysis and integration of existing datasets and database resources, with the ultimate aim to elucidate the genetic architecture of cancer risk and related outcomes (e.g., risk prediction or reduction, survival, or response to treatment, etc.). The goal of t...
Source: NIH Funding Opportunities (Notices, PA, RFA) - July 22, 2020 Category: Research Source Type: funding

Secondary Analysis and Integration of Existing Data to Elucidate the Genetic Architecture of Cancer Risk and Related Outcomes (R01 Clinical Trial Not Allowed)
Funding Opportunity PAR-20-276 from the NIH Guide for Grants and Contracts. Through this funding opportunity announcement (FOA), the National Cancer Institute (NCI) along with the National Human Genome Research Institute (NHGRI) and National Institute of Dental and Craniofacial Research (NIDCR) encourages submission of applications proposing to conduct secondary data analysis and integration of existing datasets and database resources, with the ultimate aim to elucidate the genetic architecture of cancer risk and related outcomes (e.g., risk prediction or reduction, survival, or response to treatment, etc.). The goal of t...
Source: NIH Funding Opportunities (Notices, PA, RFA) - July 22, 2020 Category: Research Source Type: funding

BRAIN Initiative: Tools for Germline Gene Editing in Marmosets (U01 - Clinical Trial Not Allowed)
Funding Opportunity RFA-DA-21-006 from the NIH Guide for Grants and Contracts. The purpose of this FOA isto develop tools and technologies to conduct cientifically rigorous, ethical, efficient, and cost-effective research infrastructure that supports germline and somatic transgenic and gene editing studies in the common marmoset (Callithrix jacchus). These studies should to answer crucial scientific questions that require genetic perturbation in a non-human primate model organism with the aim of supporting BRAIN goals of understanding the brain in health an disease. (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - July 17, 2020 Category: Research Source Type: funding

Using Human Cell Animal Chimera Brains to Study HIV Latency and Pathology R01 - Clinical Trials Not Allowed
Funding Opportunity RFA-DA-21-026 from the NIH Guide for Grants and Contracts. Recent technical advancements have enabled generating human cell-mice chimeric brains by engrafting human iPSC-derived primitive neural progenitor cells and/or cord blood-derived microglial progenitor cells into neonatal mouse. In the chimeric brain, human neural progenitor cells or microglial cells differentiate, migrate, and distribute throughout the mouse brain. They are eventually functionally integrated into various brain regions. Such successes provide opportunities to define the structure, function, genetics and plasticity of functional ...
Source: NIH Funding Opportunities (Notices, PA, RFA) - July 13, 2020 Category: Research Source Type: funding

Center for Inherited Disease Research (CIDR) High Throughput Sequencing and Genotyping Resource Access (X01)
Funding Opportunity PAR-20-230 from the NIH Guide for Grants and Contracts. The Center for Inherited Disease Research (CIDR) high-throughput genotyping, sequencing and supporting statistical genetics services are designed to aid the identification of genes or genetic modifications that contribute to human health and disease or to enhance existing collections of well-phenotyped specimens by the addition of genotype or next-generation sequence data. The laboratory specializes in genomic services that cannot be efficiently carried out in individual investigator laboratories. CIDR provides the most up-to-date platforms, servi...
Source: NIH Funding Opportunities (Notices, PA, RFA) - June 11, 2020 Category: Research Source Type: funding