Human Leukocyte Antigen (HLA) and Killer-cell Immunoglobulin-like Receptor (KIR) Region Genomics in Immune-Mediated Diseases (U01 Clinical Trial Not Allowed)
Funding Opportunity RFA-AI-24-017 from the NIH Guide for Grants and Contracts. The purpose of this notice of funding opportunity (NOFO) is to support research that 1) defines associations between variations in human leukocyte antigen (HLA) and killer cell immunoglobulin-like receptor (KIR) genetic regions and immune-mediated diseases, 2) elucidates mechanisms underlying these associations with the goal of advancing therapeutic opportunities, and/or 3) validates association data in order to improve the predictive power of clinical disease screening. (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - April 23, 2024 Category: Research Source Type: funding

Notice of Early Expiration of "Notice of Special Interest (NOSI): Molecular and Genetic Characterization of Inborn Errors of Immunity", NOT-AI-21-082
Notice NOT-AI-24-027 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - March 20, 2024 Category: Research Source Type: funding

New Approaches for Measuring Brain Changes Across Longer Timespans (R21 Clinical Trial Optional)
Funding Opportunity PAR-24-161 from the NIH Guide for Grants and Contracts. The purpose of this funding opportunity is to encourage multidisciplinary investigators to submit applications developing exploratory, highly novel new approaches, or innovative applications of existing approaches to measure brain activity, connectivity, genomics, or other aspects across the age spectrum of neurodevelopment. The overarching goal is to extend our understanding of brain development and aging, including studies of the neurodevelopmental origins of later health and disease, by improving repeated measures across longer epochs of the ...
Source: NIH Funding Opportunities (Notices, PA, RFA) - March 19, 2024 Category: Research Source Type: funding

New Approaches for Measuring Brain Changes Across Longer Timespans (R01 Clinical Trial Optional)
Funding Opportunity PAR-24-160 from the NIH Guide for Grants and Contracts. The purpose of this funding opportunity is to encourage multidisciplinary investigators to develop new approaches or apply existing approaches in novel ways to measure brain activity, connectivity, genomics, or other aspects across the age spectrum of neurodevelopment. The overarching goal is to extend our understanding of brain development and aging, including studies of the neurodevelopmental origins of later health and disease. Research can include healthy human participants of any age, specific clinical groups such as those with cognitive, m...
Source: NIH Funding Opportunities (Notices, PA, RFA) - March 19, 2024 Category: Research Source Type: funding

Notice of Participation of NIMH in PAR-23-302, "Developing novel theory and methods for understanding the genetic architecture of complex human traits (R01 Clinical Trial Not Allowed)"
Notice NOT-MH-24-200 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - March 6, 2024 Category: Research Source Type: funding

Notice of Change to Application Due Date for RFA-AA-24-003,"Limited Competition: Collaborative Study on the Genetics of Alcoholism (COGA) (U10 Clinical Trial Not Allowed)"
Notice NOT-AA-24-006 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - February 29, 2024 Category: Research Source Type: funding

INCLUDE (INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE) Predoctoral to Postdoctoral Fellow Transition Award (F99/K00 Clinical Trial Not Allowed)
Funding Opportunity RFA-OD-24-007 from the NIH Guide for Grants and Contracts. The purpose of the INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE (INCLUDE) Predoctoral to postdoctoral Fellow Transition award (F99/K00) is to recruit exceptional graduate students from diverse research fields to pursue postdoctoral training focused on Down syndrome related research. Talented graduate students from disciplines including, but not limited to, genetics, biochemistry, data science, imaging, engineering and neurobiology are invited to apply to this opportunity. Prospective applicants are ...
Source: NIH Funding Opportunities (Notices, PA, RFA) - February 22, 2024 Category: Research Source Type: funding

Transformative Research on the Basic Mechanisms of Polysubstance use in Addiction (R01 - Clinical Trials Optional)
Funding Opportunity RFA-DA-25-043 from the NIH Guide for Grants and Contracts. This notice of funding opportunity (NOFO) will support projects proposing mechanistic studies that will transform our understanding of polysubstance use in addiction. These hypothesis-based, exploratory projects may investigate mechanisms of polysubstance use at the behavioral, cognitive, cellular, circuit, genetic, epigenetic, pharmacological and/or computational levels. (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - February 20, 2024 Category: Research Source Type: funding

BRAIN Initiative: Scaled reagent resources for brain cell type-specific access across vertebrate species (U01 Clinical Trial Not Allowed)
Funding Opportunity RFA-MH-25-100 from the NIH Guide for Grants and Contracts. This BRAIN Initiative Notice of Funding Opportunity (NOFO) is to scale up efforts for viral, non-viral, transgenic, and gene regulatory element screening technologies and create reagent resources to access brain cell types. This NOFO is part of the BRAIN Initiative Armamentarium for Brain Cell Access transformative project. Reagent development efforts will apply gene transfer, gene regulation, genome engineering, activity sensor/effector, and atlasing technologies for use in both genetically tractable and less tractable systems, including pri...
Source: NIH Funding Opportunities (Notices, PA, RFA) - February 20, 2024 Category: Research Source Type: funding

BRAIN Initiative: Production and distribution facilities for brain cell type-specific access reagents (U24 Clinical Trial Not Allowed)
Funding Opportunity RFA-MH-25-105 from the NIH Guide for Grants and Contracts. This BRAIN Initiative Notice of Funding Opportunity (NOFO) is to support scaled reagent production and distribution facilities involving technologies to access brain cell types. Facilities for production and distribution of these reagents by a broad and diverse set of neuroscientists will be encouraged. This NOFO is part of the BRAIN Initiative Armamentarium for Brain Cell Access transformative project. Efforts will be supported to produce and distribute gene transfer, gene regulation, and genome engineering reagents for use in both genetical...
Source: NIH Funding Opportunities (Notices, PA, RFA) - February 20, 2024 Category: Research Source Type: funding

Limited Competition: Collaborative Study on the Genetics of Alcoholism (COGA) (U10 Clinical Trial Not Allowed)
Funding Opportunity RFA-AA-24-003 from the NIH Guide for Grants and Contracts. This notice of funding opportunity (NOFO) is a limited competition notice of funding opportunity (NOFO) soliciting a cooperative agreement (U10) application from investigators currently supported under an existing study, entitled Collaborative Study on the Genetics of Alcoholism (COGA). The purpose of COGA is to identify genetic variants that affect the susceptibility to develop alcohol use disorder. The goals of this limited competition are to continue to advance the understanding of the complexity of the genotypes and phenotypes that contri...
Source: NIH Funding Opportunities (Notices, PA, RFA) - February 14, 2024 Category: Research Source Type: funding

Investigating Distinct and Overlapping Mechanisms in TDP-43 Proteinopathies, including in LATE, FTD and other ADRDs (R01 - Clinical Trial Not Allowed)
Funding Opportunity PAR-24-148 from the NIH Guide for Grants and Contracts. This FOA would support establishing deeper mechanistic insight and causal relationships between TDP-43 pathology and phenotypic outcomes, as well as mechanistic interactions between TDP-43 and other co-pathologies, such TMEM106B. Additionally, it would include comparisons (including mechanistic, molecular, structural, cellular, genetic, -omic, anatomical, neuropathological, etc.) between TDP-43 proteinopathies, including LATE, with or without AD-NC, and FTD and/or ALS. (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - February 6, 2024 Category: Research Source Type: funding

Limited Competition: Specific Pathogen Free Macaque Colonies to Support HIV/AIDS Research (U42 Clinical Trial Not Allowed)
Funding Opportunity PAR-24-129 from the NIH Guide for Grants and Contracts. The purpose of this Notice of Funding Opportunity (NOFO) is to provide continuing support for specific pathogen-free (SPF) macaque colonies previously funded under the auspices of PAR-21-089 and PAR-18-669 that support Human Immunodeficiency Virus (HIV)/Acquired Immunodeficiency Syndrome (AIDS) research. Breeding colonies are essential to sustain appropriate SPF macaques for research related to HIV/AIDS. Pedigree SPF macaques are free of certain viruses, which may confound the results of HIV/AIDS-related investigations or present a risk to the p...
Source: NIH Funding Opportunities (Notices, PA, RFA) - January 22, 2024 Category: Research Source Type: funding

Notice of Pre-Application Webinar for Discovery of the Genetic Basis of Childhood Cancers and of Structural Birth Defects: Gabriella Miller Kids First Pediatric Research Program (X01 Clinical Trial Not Allowed)
Notice NOT-RM-24-004 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - January 19, 2024 Category: Research Source Type: funding

Limited Competition: Specific Pathogen Free Macaque Colonies (U42 Clinical Trial Not Allowed)
Funding Opportunity PAR-24-078 from the NIH Guide for Grants and Contracts. The purpose of this Notice of Funding Opportunity (NOFO) is to provide continuing support for specific pathogen-free (SPF) macaque colonies previously funded under the auspices of PAR-21-089 and PAR-18-669 that support Human Immunodeficiency Virus (HIV)/Acquired Immunodeficiency Syndrome (AIDS) research. Breeding colonies are essential to sustain appropriate SPF macaques for research related to HIV/AIDS. Pedigree SPF macaques are free of certain viruses, which may confound the results of HIV/AIDS-related investigations or present a risk to the p...
Source: NIH Funding Opportunities (Notices, PA, RFA) - January 9, 2024 Category: Research Source Type: funding