Ancillary Studies to the NIDDK Inflammatory Bowel Disease Genetics Consortium (R01- Clinical Trial Optional)
The NIDDK Inflammatory Bowel Disease Genetics Consortium (IBDGC), in collaboration with the International IBD Genetics Consortium, has identified about 200 susceptibility loci for IBD. The IBDGC has recently been awarded renewed funding to identify causal genes and genetic variants within these loci, and to elucidate the mechanisms through which they contribute to the pathophysiology of IBD. However, the IBDGC's current resources permit them to explore the functions of only a limited set of genes within a limited set of physiological domains. The purpose of this Funding Opportunity Announcement (FOA) is to expand the numbe...
Source: NIDDK Funding Opportunities - September 12, 2018 Category: Endocrinology Source Type: funding

Communication and Decision Making for Individuals with Inherited Cancer Syndromes (U01 Clinical Trial Optional).
Funding Opportunity RFA-CA-19-001 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) is associated with the Beau Biden Cancer MoonshotSM Initiative (https://www.cancer.gov/research/key-initiatives/moonshot-cancer-initiative) that is intended to accelerate cancer research. The purpose of this FOA is to develop, test, and evaluate interventions and implementation approaches, or adapt existing approaches, to improve patient/provider/family risk communication and decision making for individuals and families with an inherited susceptibility to cancer. Specifically, this FOA targets the fol...
Source: NIH Funding Opportunities (Notices, PA, RFA) - September 10, 2018 Category: Research Source Type: funding

Utilizing the PLCO Biospecimens Resource to Bridge Gaps in Cancer Etiology and Early Detection Research (U01 Clinical Trial Not Allowed)
Funding Opportunity PAR-18-913 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) encourages the submission of applications that propose to advance research in cancer etiology and early detection biomarkers, utilizing the advantages of the unique biorepository resources of the NCI-sponsored Prostate, Lung, Colorectal, and Ovarian Cancer (PLCO) Screening Trial. The PLCO Biorepository offers high-quality, prospectively collected, serial pre-diagnostic blood samples from the PLCO screened arm participants, and a onetime collection of buccal cells from the control arm participants. Availa...
Source: NIH Funding Opportunities (Notices, PA, RFA) - September 7, 2018 Category: Research Source Type: funding

U.S. - India Collaborative Vision Research Program (R01 Clinical Trial Not Allowed)
Funding Opportunity PAR-18-912 from the NIH Guide for Grants and Contracts. This funding Opportunity Announcement (FOA) encourages Multiple Principal Investigator (Multi-PD/PI) applications from United States (U.S.) and Indian institution as bilateral collaborations that will advance science and technology important to understanding, preventing, and treating blinding eye diseases, visual disorders, and their complications. Areas of Research Collaboration: Applications are encouraged from organization/institutions that propose to conduct research on the basic biology and/or genetics of ophthalmic diseases through collabora...
Source: NIH Funding Opportunities (Notices, PA, RFA) - September 7, 2018 Category: Research Source Type: funding

New Computational Methods for Understanding the Functional Role of DNA Variants that are Associated with Mental Disorders (R01 Clinical Trial Not Allowed)
Funding Opportunity PA-18-908 from the NIH Guide for Grants and Contracts. The purpose of this Funding Opportunity Announcement (FOA) is to support the development of advanced computational, bioinformatic and statistical tools to determine the functional relevance of genetic variants associated with mental disorders of complex etiologies identified through genome-wide association or sequencing studies. The overarching goal of this initiative is to support the development of innovative computational methods that facilitate the elucidation of the functionality of genetic variants associated with mental illness, taking into ...
Source: NIH Funding Opportunities (Notices, PA, RFA) - August 29, 2018 Category: Research Source Type: funding

New Computational Methods for Understanding the Functional Role of DNA Variants that are Associated with Mental Disorders (R01 (Collab) Clinical Trial Not Allowed)
Funding Opportunity PA-18-907 from the NIH Guide for Grants and Contracts. The purpose of this Funding Opportunity Announcement (FOA) is to support the development of advanced computational, bioinformatic and statistical tools to determine the functional relevance of genetic variants associated with mental disorders of complex etiologies identified through genome-wide association or sequencing studies. The overarching goal of this initiative is to support the development of innovative computational methods that facilitate the elucidation of the functionality of genetic variants associated with mental illness, taking into ...
Source: NIH Funding Opportunities (Notices, PA, RFA) - August 29, 2018 Category: Research Source Type: funding

Leveraging Electronic Medical Records for Psychiatric Genetic Research (R01 Clinical Trial Not Allowed)
Funding Opportunity PAR-18-904 from the NIH Guide for Grants and Contracts. The purpose of this funding opportunity announcement (FOA) is to support projects that implement creative, efficient molecular epidemiologic approaches that incorporate individual genetic information, including polygenic as well as specific genetic risk variants, in existing large, population-based cohorts, registries and/or health systems to conduct analyses that advance our understanding of the complex etiology of severe mental disorders. The ultimate objective of this funding opportunity is the elucidation of the complex interplays of genetic (...
Source: NIH Funding Opportunities (Notices, PA, RFA) - August 16, 2018 Category: Research Source Type: funding

Leveraging Electronic Medical Records for Psychiatric Genetic Research (R01 (Collab) Clinical Trial Not Allowed)
Funding Opportunity PAR-18-905 from the NIH Guide for Grants and Contracts. The ultimate objective of this funding opportunity is the elucidation of the complex interplays of genetic (e.g., polygenic) risk, in addition to specific risk loci and networks, and environmental factors, in human populations, which will lead to better understanding, diagnosis, and ultimately treatment of mental disorders. For a linked set of collaborative R01s, each site has its own Program Director(s)/Principal Investigator(s), and the program provides a mechanism for cross-site coordination and communication. Collaborative studies are appropri...
Source: NIH Funding Opportunities (Notices, PA, RFA) - August 16, 2018 Category: Research Source Type: funding

Approaches to Identify and Care for Individuals with Inherited Cancer Syndromes (U01 Clinical Trial Required)
Funding Opportunity RFA-CA-19-017 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) is associated with the Beau Biden Cancer MoonshotSM Initiative that is intended to accelerate cancer research. The purpose of this FOA is to increase case ascertainment and appropriate follow-up care, optimizing the delivery of evidence-based healthcare for individuals at high risk of cancer due to an inherited genetic susceptibility. Specifically, this FOA targets the following area designated as a scientific priority by the Blue Ribbon Panel (BRP) Recommendation G: "To realize the potential of ...
Source: NIH Funding Opportunities (Notices, PA, RFA) - August 10, 2018 Category: Research Source Type: funding

Limited Competition: Additional Sequencing for the Alzheimer's Disease Sequencing Project: Opportunity for Revision Requests for Active Cooperative Agreements (U01 Clinical Trial Not Allowed)
Funding Opportunity PAR-18-890 from the NIH Guide for Grants and Contracts. The National Institute on Aging invites revision applications to ongoing NIA-supported Cooperative Agreements in the area of the genetics of Alzheimer's Disease and Alzheimer's Disease Related Dementias (AD/ADRD). This Funding Opportunity Announcement (FOA) invites applications specific to sample acquisition, genome wide association studies, whole genome sequencing, quality control checking, variant calling, and data calling that will support the generation of data for the Alzheimer's Disease Sequencing Project Follow-Up Study. (Source: NIH Fundin...
Source: NIH Funding Opportunities (Notices, PA, RFA) - August 3, 2018 Category: Research Source Type: funding

Limited Competition: Renewal of, and Revisions to, the Alzheimer's Disease Genetics Consortium (U01 Clinical Trial Not Allowed)
Funding Opportunity PAR-18-889 from the NIH Guide for Grants and Contracts. This FOA invites the NIA Alzheimer's Disease Genetics Consortium to submit revision and/or renewal applications in the area of the genetics of Alzheimer's Disease. (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - August 3, 2018 Category: Research Source Type: funding

BRAIN Initiative: Development of Novel Tools to Probe Cell-Specific and Circuit-Specific Processes in Human and Non-Human Primate Brain (UG3/UH3 Clinical Trial Optional)
Funding Opportunity RFA-MH-19-135 from the NIH Guide for Grants and Contracts. The purpose of this Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative is to encourage applications that will develop and validate novel tools to facilitate the detailed analysis and manipulation of complex circuits and provide insights into cellular interactions that underlie brain function. Critical advances in the treatment of brain disorders in human populations are hindered by our lack of ability to monitor and manipulate circuitry in safe, minimally-invasive ways. Clinical intervention with novel cell and cir...
Source: NIH Funding Opportunities (Notices, PA, RFA) - August 3, 2018 Category: Research Source Type: funding

Biologic Factors Underlying Dental, Oral, and Craniofacial Health Disparities (R01 - Clinical Trial Not Allowed)
Funding Opportunity PAR-18-875 from the NIH Guide for Grants and Contracts. The purpose of this Funding Opportunity Announcement (FOA) is to support investigator-initiated studies designed to identify and understand biologic factors (microbial, immune, genetic) that contribute to disparities in dental, oral, and craniofacial disease onset, progression, and persistence. (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - July 25, 2018 Category: Research Source Type: funding

Research to Advance Vaccine Safety (R01 Clinical Trial Not Allowed)
Funding Opportunity PA-18-873 from the NIH Guide for Grants and Contracts. The purpose of this Funding Opportunity Announcement (FOA) is to support research that will contribute to the overall understanding of vaccine safety. This research opportunity encourages studies that address scientific areas potentially relevant to vaccine safety, such as: 1) characterization of physiological and immunological responses to vaccines and vaccine components, including different adjuvants; 2) how genetic variations affect immune/physiological responses that may impact vaccine safety; 3) identification of risk factors (e.g., infection ...
Source: NIH Funding Opportunities (Notices, PA, RFA) - July 24, 2018 Category: Research Source Type: funding

Research to Advance Vaccine Safety (R21 Clinical Trial Not Allowed)
Funding Opportunity PA-18-872 from the NIH Guide for Grants and Contracts. The purpose of this Funding Opportunity Announcement (FOA) is to support research that will contribute to the overall understanding of vaccine safety. This research opportunity encourages studies that address scientific areas potentially relevant to vaccine safety such as 1) characterization of physiological and immunological responses to vaccines and vaccine components, including different adjuvants; 2) how genetic variations affect immune/physiological responses that may impact vaccine safety; 3) identification of risk factors (e.g., infection hi...
Source: NIH Funding Opportunities (Notices, PA, RFA) - July 24, 2018 Category: Research Source Type: funding

Novel Approaches for Relating Genetic Variation to Function and Disease (R21 Clinical Trial Not Allowed)
Funding Opportunity PA-18-867 from the NIH Guide for Grants and Contracts. Genome-wide association studies and other disease studies have identified many variants that are statistically associated with disease risk, disease protection, or other traits. However, such studies do not generally show which specific variants in genomic elements cause these effects, or how they result in differences in function. Similarly, genomic sequencing studies in clinical settings have identified many variants in healthy and diseased individuals. However, the pathogenicity of such variants is often unknown, leading to their classification ...
Source: NIH Funding Opportunities (Notices, PA, RFA) - July 23, 2018 Category: Research Source Type: funding

Novel Approaches for Relating Genetic Variation to Function and Disease (R01 Clinical Trial Not Allowed)
Funding Opportunity PA-18-868 from the NIH Guide for Grants and Contracts. Genome-wide association studies have found many variants associated with disease risk, disease protection, or other traits. However, these studies generally identify many variants that are statistically associated with the trait, but do not show which variants in genomic elements cause these effects, or how they result in differences in function. Similarly, clinical genomic sequencing studies have identified many variants in healthy and diseased individuals, but the pathogenicity of such variants is usually unknown, leading to their classification ...
Source: NIH Funding Opportunities (Notices, PA, RFA) - July 23, 2018 Category: Research Source Type: funding

Limited Competition: NIDCD National Temporal Bone, Hearing and Balance Pathology Resource Registry (U24 Clinical Trial Not Allowed)
Funding Opportunity RFA-DC-19-002 from the NIH Guide for Grants and Contracts. The NIDCD Temporal Bone Registry is a national research resource for human auditory and vestibular research. Its fundamental purpose is to coordinate information about specimens of the human ear and to recruit potential temporal bone donors. The Registry coordinates specimen collection, information recording and data management of specimens, and provides public information, including an up-to-date website about human ear specimens for research. It is not a simple database or tissue bank for human ear specimens. Applications are encouraged that ...
Source: NIH Funding Opportunities (Notices, PA, RFA) - July 5, 2018 Category: Research Source Type: funding

Oncology Co-Clinical Imaging Research Resources to Encourage Consensus on Quantitative Imaging Methods and Precision Medicine (U24 - Clinical Trial Optional)
Funding Opportunity PAR-18-841 from the NIH Guide for Grants and Contracts. The purpose of this Funding Opportunity Announcement (FOA) is to invite Cooperative Agreement applications to develop research resources that will encourage a consensus on how Quantitative Imaging (QI) methods are optimized to improve the quality of imaging results for co-clinical trials. The scientific goals of this FOA are to: (a) perform the appropriate optimization of the pre-clinical quantitative imaging methods, (b) implement the optimized methods in the co-clinical trial, and finally (c) populate a web-accessible research resource with all ...
Source: NIH Funding Opportunities (Notices, PA, RFA) - June 28, 2018 Category: Research Source Type: funding

Notice of Change to Application Types Allowed in PA-17-239 "Secondary Analysis and Integration of Existing Data to Elucidate the Genetic Architecture of Cancer Risk and Related Outcomes (R01)"
Notice NOT-CA-18-080 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - June 25, 2018 Category: Research Source Type: funding

Rare Genetic Syndromes as a Window into the Genetic Architecture of Mental Disorders (Collaborative U01 Clinical Trial Not Allowed)
Funding Opportunity RFA-MH-19-201 from the NIH Guide for Grants and Contracts. This initiative will foster collaborative and coordinated efforts to characterize the underlying genetic architecture of diverse neuropsychiatric phenotypes within and across rare genetic disorders and identify the shared genetic risk across rare and idiopathic neuropsychiatric disorders. Projects from multi-disciplinary teams will utilize genome-wide data to comprehensively assess the contribution of genetic variation to the variable expressivity and incomplete penetrance of neuropsychiatric phenotypes across rare genetic disorders. Projects a...
Source: NIH Funding Opportunities (Notices, PA, RFA) - June 7, 2018 Category: Research Source Type: funding

Rare Genetic Syndromes as a Window into the Genetic Architecture of Mental Disorders (U01 Clinical Trial Not Allowed)
Funding Opportunity RFA-MH-19-200 from the NIH Guide for Grants and Contracts. This initiative will foster collaborative and coordinated efforts to characterize the underlying genetic architecture of diverse neuropsychiatric phenotypes within and across rare genetic disorders and identify the shared genetic risk across rare and idiopathic neuropsychiatric disorders. Projects from multi-disciplinary teams will utilize genome-wide data to comprehensively assess the contribution of genetic variation to the variable expressivity and incomplete penetrance of neuropsychiatric phenotypes across rare genetic disorders. Projects a...
Source: NIH Funding Opportunities (Notices, PA, RFA) - June 7, 2018 Category: Research Source Type: funding

Biomarkers Discovery In Parkinsonism (U01 Clinical Trial Optional)
Funding Opportunity PAR-18-800 from the NIH Guide for Grants and Contracts. The purpose of this funding opportunity announcement (FOA) is to support hypothesis-driven research to discover human biomarkers in Parkinsons disease and other Parkinsonian syndromes, as a component of the NINDS Parkinsons Disease Biomarkers Program (PDBP). This FOA encourages biomarkers discovery projects in 1) genetically causal Parkinson's disease, especially for particular sub-types of Parkinson's Disease (PD), including genetic cohorts, biologically defined cohorts of idiopathic PD, or ethnic subgroups of idiopathic PD; 2) The differentiatio...
Source: NIH Funding Opportunities (Notices, PA, RFA) - May 23, 2018 Category: Research Source Type: funding

Genetic analysis of non-human animal models to understand the genomic architecture of substance use disorders and addictive behaviors (U01 Clinical Trial Not Allowed)
Funding Opportunity PAR-18-789 from the NIH Guide for Grants and Contracts. The goals of this initiative are to discover allelic variants, genomic alterations, and functional changes associated with addictive behaviors in non-human animals through systems studies that employ genetic and genomics strategies. We also encourage proposals that take genetic and/or genomics approaches to integrate data, delineate gene networks, and uncover the function of known or newly discovered genetic or epigenetic variants. (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - May 16, 2018 Category: Research Source Type: funding

Collaborative Cross (CC) Mouse Model Generation and Discovery of Immunoregulatory Mechanisms (R21 Clinical Trials Not Allowed)
Funding Opportunity PAR-18-781 from the NIH Guide for Grants and Contracts. The purpose of this Funding Opportunity Announcement (FOA) is to support the use of Collaborative Cross (CC) mouse lines to advance understanding of the host genetics involved in immune regulation and function and to further develop CC mouse lines that more faithfully reproduce human immune responses. Research areas supported by this FOA include: immune system development, function or regulation; mechanisms governing immune response to infectious pathogens, vaccines or adjuvants; host susceptibility factors and mechanisms of pathogen-induced immun...
Source: NIH Funding Opportunities (Notices, PA, RFA) - May 11, 2018 Category: Research Source Type: funding

BRAIN Initiative: Development and Validation of Novel Tools to Probe Cell-Specific and Circuit-Specific Processes in the Brain (R01 Clinical Trial Not Allowed)
Funding Opportunity RFA-MH-19-136 from the NIH Guide for Grants and Contracts. The purpose of this Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative is to encourage applications that will develop and validate novel tools to facilitate the detailed analysis of complex circuits and provide insights into cellular interactions that underlie brain function. The new tools and technologies should inform and/or exploit cell-type and/or circuit-level specificity. Plans for validating the utility of the tool/technology will be an essential feature of a successful application. The development of new ge...
Source: NIH Funding Opportunities (Notices, PA, RFA) - May 3, 2018 Category: Research Source Type: funding

Secondary Analyses in Obesity, Diabetes and Digestive and Kidney Diseases (R21 Clinical Trial Not Allowed)
Funding Opportunity PA-18-741 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) encourages R21 applications that propose to conduct secondary analyses of existing data sets relevant to diabetes and selected endocrine and metabolic diseases including thyroid, parathyroid and Cushings diseases and acromegaly; and genetic metabolic disease including cystic fibrosis, lysosomal storage diseases, and disorders of the urea cycle, amino acid metabolism and metal transport where the focus is on peripheral metabolism or organ function; obesity, liver diseases, alimentary GI tract diseases and ...
Source: NIH Funding Opportunities (Notices, PA, RFA) - April 3, 2018 Category: Research Source Type: funding

Secondary Analyses in Obesity, Diabetes and Digestive and Kidney Diseases (R21 Clinical Trial Not Allowed)
This Funding Opportunity Announcement (FOA) encourages R21 applications that propose to conduct secondary analyses of existing data sets relevant to diabetes and selected endocrine and metabolic diseases including thyroid, parathyroid and Cushings diseases and acromegaly; and genetic metabolic disease including cystic fibrosis, lysosomal storage diseases, and disorders of the urea cycle, amino acid metabolism and metal transport where the focus is on peripheral metabolism or organ function; obesity, liver diseases, alimentary GI tract diseases and nutrition; kidney, urologic, and hematologic diseases. The goal of this prog...
Source: NIDDK Funding Opportunities - April 3, 2018 Category: Endocrinology Source Type: funding

Small Research Grants for Establishing Basic Science-Clinical Collaborations to Understand Structural Birth Defects (R03 - Clinical Trial Not Allowed)
Funding Opportunity PAR-18-734 from the NIH Guide for Grants and Contracts. The purpose of this funding opportunity announcement (FOA) is to promote initial establishment of basic science-clinical collaborations by providing small grants to teams of basic scientists, physician scientists, and/or clinicians. These interdisciplinary teams may include but are not limited to the following: developmental biologists, cell biologists, geneticists, genomicists, physician scientists including individuals with DVM/VMD degrees, clinicians, epidemiologists, biostatisticians, and/or bioinformaticists. (Source: NIH Funding Opportunitie...
Source: NIH Funding Opportunities (Notices, PA, RFA) - March 30, 2018 Category: Research Source Type: funding

Small Research Grants for Analyses of Data for the Gabriella Miller Kids First Data Resource (R03 - Clinical Trial Not Allowed)
Funding Opportunity PAR-18-733 from the NIH Guide for Grants and Contracts. The NIH Common Fund has established the Gabriella Miller Kids First Pediatric Research Program (Kids First) to develop a pediatric research data resource populated by genome sequence and phenotype data that will be of high value for the communities of investigators who study the genetics of childhood cancers and/or structural birth defects. The overall goal of the Gabriella Miller Kids First Pediatric Data Resource is to help researchers understand the underlying mechanisms of these conditions, leading to more refined diagnostic capabilities and u...
Source: NIH Funding Opportunities (Notices, PA, RFA) - March 30, 2018 Category: Research Source Type: funding

Accelerating Basic and Translational Research in Hidradenitis Suppurativa (R21 Clinical Trial Not Allowed)
Funding Opportunity PA-18-718 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) will support high risk and high reward basic and translational studies aimed at understanding the etiology, and the cellular and molecular mechanisms, including the environmental, genetic, epigenetic, biologic, and immunologic factors causing and/or associated with Hidradenitis Suppurativa. The purpose is to accelerate discovery in this field of research and to apply new knowledge to improve patients condition and ultimately better control disease. This FOA intends to support a broad range of mechanistic ...
Source: NIH Funding Opportunities (Notices, PA, RFA) - March 28, 2018 Category: Research Source Type: funding

Accelerating Basic and Translational Research in Hidradenitis Suppurativa (R01 Clinical Trial Not Allowed)
Funding Opportunity PA-18-719 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) will support basic and translational studies aimed at understanding the etiology, and the cellular and molecular mechanisms, including the environmental, genetic, epigenetic, biologic, and immunologic factors causing and/or associated with Hidradenitis Suppurativa. The purpose is to accelerate discovery in this field of research and to apply new knowledge to improve patients condition and ultimately better control disease. This FOA intends to support a broad range of mechanistic studies using animal and h...
Source: NIH Funding Opportunities (Notices, PA, RFA) - March 28, 2018 Category: Research Source Type: funding

NEI Institutional Mentored Physician Scientist Award (K12 Clinical Trial Optional)
Funding Opportunity PAR-18-726 from the NIH Guide for Grants and Contracts. The purpose of this Funding Opportunity Announcement (FOA) is to encourage institutions to propose creative and innovative institutional research career development programs which prepare clinically-trained vision scientists for independent research careers. This initiative is intended to expand and strengthen the community of investigators engaged in clinical research. Such an increase in the number of well-trained clinical researchers is necessary to achieve a pool of scientists with contemporary, multidisciplinary expertise able to leverage rec...
Source: NIH Funding Opportunities (Notices, PA, RFA) - March 28, 2018 Category: Research Source Type: funding

BRAIN Initiative: New Technologies and Novel Approaches for Large-Scale Recording and Modulation in the Nervous System (R01 Clinical Trials Not Allowed)
Funding Opportunity RFA-NS-18-020 from the NIH Guide for Grants and Contracts. Understanding the dynamic activity of neural circuits is central to the NIH BRAIN Initiative. This FOA seeks applications for proof-of-concept testing and development of new technologies and novel approaches for largescale recording and manipulation of neural activity to enable transformative understanding of dynamic signaling in the nervous system. In particular, we seek exceptionally creative approaches to address major challenges associated with recording and manipulating neural activity, at or near cellular resolution, at multiple spatial a...
Source: NIH Funding Opportunities (Notices, PA, RFA) - March 14, 2018 Category: Research Source Type: funding

BRAIN Initiative: Optimization of Transformative Technologies for Large Scale Recording and Modulation in the Nervous System (U01-Clinical Trials Not Allowed)
Funding Opportunity RFA-NS-18-019 from the NIH Guide for Grants and Contracts. Although invention and proof-of-concept testing of new technologies are a key component of the BRAIN Initiative, to achieve their potential these technologies must also be optimized through feedback from end-users in the context of the intended experimental use. This seeks applications for the optimization of existing and emerging technologies and approaches that have potential to address major challenges associated with recording and manipulating neural activity, at or near cellular resolution, at multiple spatial and temporal scales, in any r...
Source: NIH Funding Opportunities (Notices, PA, RFA) - March 14, 2018 Category: Research Source Type: funding

Innovative Therapies and Tools for Screenable Disorders (R01 Clinical Trial Optional)
Funding Opportunity PAR-18-689 from the NIH Guide for Grants and Contracts. This FOA encourages research relevant to the development of therapeutic interventions for potentially fatal or disabling conditions that have been identified through newborn screening, as well as "high priority" genetic conditions where screening may be possible in the near future. Demonstrating the benefits of treatment is often a primary criterion for including a condition on a newborn screening panel; therefore, this FOA, a "high priority" condition is one where screening is not currently recommended but would significantly ...
Source: NIH Funding Opportunities (Notices, PA, RFA) - March 1, 2018 Category: Research Source Type: funding

Innovative Therapies and Tools for Screenable Disorders (R03 Clinical Trial Optional)
Funding Opportunity PAR-18-690 from the NIH Guide for Grants and Contracts. This FOA encourages research relevant to the development of therapeutic interventions for potentially fatal or disabling conditions that have been identified through newborn screening, as well as "high priority" genetic conditions where screening may be possible in the near future. Demonstrating the benefits of treatment is often a primary criterion for including a condition on a newborn screening panel; therefore, this FOA, a "high priority" condition is one where screening is not currently recommended but would significantly ...
Source: NIH Funding Opportunities (Notices, PA, RFA) - March 1, 2018 Category: Research Source Type: funding

Innovative Therapies and Tools for Screenable Disorders (R21 Clinical Trial Optional)
Funding Opportunity PAR-18-691 from the NIH Guide for Grants and Contracts. This FOA encourages research relevant to the development of therapeutic interventions for potentially fatal or disabling conditions that have been identified through newborn screening, as well as "high priority" genetic conditions where screening may be possible in the near future. Demonstrating the benefits of treatment is often a primary criterion for including a condition on a newborn screening panel; therefore, this FOA, a "high priority" condition is one where screening is not currently recommended but would significantly ...
Source: NIH Funding Opportunities (Notices, PA, RFA) - March 1, 2018 Category: Research Source Type: funding

Notice of NIGMS Participation in PA-18-610 "Development of Novel and Emerging Technologies for Cryogenic or Long-term Preservation and Revival of Drosophila and Zebrafish Genetic Stocks (R43/R44 Clinical Trial Not Allowed)"
Notice NOT-GM-18-020 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - February 23, 2018 Category: Research Source Type: funding

Notice of NIGMS Participation in PA-18-609 Development of Novel and Emerging Technologies for Cryogenic or Long-term Preservation and Revival of Drosophila and Zebrafish Genetic Stocks (R41/R42 Clinical Trial Not Allowed)
Notice NOT-GM-18-019 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - February 23, 2018 Category: Research Source Type: funding

Limited Competition: Specific Pathogen Free Macaque Colonies (U42 Clinical Trial Not Allowed)
Funding Opportunity PAR-18-669 from the NIH Guide for Grants and Contracts. The purpose of this Funding Opportunity Announcement is to provide continuing support for specific pathogen free (SPF) macaque colonies previously funded under the auspices of PAR-14-066. Breeding colonies are essential to sustain Human Immunodeficiency Virus (HIV)/Acquired Immunodeficiency Syndrome (AIDS) research. Pedigree SPF macaques are free of certain viruses, which can confound the results of AIDS-related investigations or present a risk to the personnel who care for the animals. The SPF macaques are genetically characterized for major hist...
Source: NIH Funding Opportunities (Notices, PA, RFA) - February 21, 2018 Category: Research Source Type: funding

Genetics of Alcohol Sensitivity and Tolerance (R01 Clinical Trial Not Allowed)
Funding Opportunity PA-18-660 from the NIH Guide for Grants and Contracts. The goal of this FOA is to develop new hypotheses and common experimental framework(s) between human - animal model studies to better understand the genetic, genomic, and epigenetic factors contributing to and underlying biological bases for the development of tolerance and the progression to alcohol dependence. (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - February 14, 2018 Category: Research Source Type: funding

Basic Research in Cancer Health Disparities (R21 Clinical Trial Not Allowed)
Funding Opportunity PAR-18-655 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) encourages grant applications from investigators interested in conducting basic, mechanistic research into the biological/genetic causes of cancer health disparities. These research project grants (R01) will support innovative studies designed to investigate biological/genetic bases of cancer disparities, such as (1) mechanistic studies of biological factors associated with cancer disparities, including those related to basic research in cancer biology or cancer prevention strategies, (2) the development...
Source: NIH Funding Opportunities (Notices, PA, RFA) - February 13, 2018 Category: Research Source Type: funding

Basic Research in Cancer Health Disparities (R01 Clinical Trials Not Allowed)
Funding Opportunity PAR-18-654 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) encourages grant applications from investigators interested in conducting basic, mechanistic research into the biological/genetic causes of cancer health disparities. These research project grants (R01) will support innovative studies designed to investigate biological/genetic bases of cancer disparities, such as (1) mechanistic studies of biological factors associated with cancer disparities, including those related to basic research in cancer biology or cancer prevention strategies, (2) the development...
Source: NIH Funding Opportunities (Notices, PA, RFA) - February 13, 2018 Category: Research Source Type: funding

Disease Mechanisms of Prenatal and Pediatric Hydrocephalus (R01 Clinical Trial Not Allowed)
Funding Opportunity PA-18-622 from the NIH Guide for Grants and Contracts. The purpose of this funding opportunity announcement (FOA) is to support hypothesis-driven research of prenatal and pediatric hydrocephalus. This FOA intends to solicit hydrocephalus research projects that examine the developmental etiology (intrinsic factors including genetics) and acquired etiology (extrinsic factors including hemorrhage and infection) of prenatal and/or pediatric hydrocephalus. Studies should focus on understanding the molecular, cellular and developmental mechanisms involved in the pathogenesis of prenatal and/or pediatric hydr...
Source: NIH Funding Opportunities (Notices, PA, RFA) - February 1, 2018 Category: Research Source Type: funding

Traceback Testing: Increasing Identification and Genetic Counseling of Mutation Carriers through Family-based Outreach (U01 Clinical Trial Optional)
Funding Opportunity PAR-18-616 from the NIH Guide for Grants and Contracts. The purpose of the Funding Opportunity Announcement (FOA) is to support research projects using a Traceback approach to genetic testing to identify unaffected individuals at increased risk for cancer in different clinical contexts and communities, including racially/ethnically diverse populations. (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - February 1, 2018 Category: Research Source Type: funding

Notice of Pre-Application Webinar for PAR-18-583 "Discovery of the Genetic Basis of Childhood Cancers and of Structural Birth Defects: Gabriella Miller Kids First Pediatric Research Program (X01 Clinical Trial Not Allowed)"
Notice NOT-RM-18-013 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - February 1, 2018 Category: Research Source Type: funding

Development of Novel and Emerging Technologies for Cryogenic or Long-term Preservation and Revival of Drosophila and Zebrafish Genetic Stocks (R43/R44 Clinical Trial Not Allowed)
Funding Opportunity PA-18-610 from the NIH Guide for Grants and Contracts. This funding opportunity announcement (FOA) encourages applications from small business concerns for Small Business Innovation Research (SBIR) projects that propose innovative research and development of technology for cryogenic or other long-term preservation and revival of Drosophila and zebrafish genetic stocks. The proposed technologies should be reliable, reproducible and cost effective for the long-term preservation and revival of wild type and laboratory created genetic stocks. (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - January 31, 2018 Category: Research Source Type: funding

Development of Novel and Emerging Technologies for Cryogenic or Long-term Preservation and Revival of Drosophila and Zebrafish Genetic Stocks (R41/R42 Clinical Trial Not Allowed)
Funding Opportunity PA-18-609 from the NIH Guide for Grants and Contracts. This funding opportunity announcement (FOA) encourages applications from small business concerns for Small Business Technology Transfer (STTR) projects that propose innovative research and development of technology for cryogenic or other long-term preservation and revival of Drosophila and zebrafish genetic stocks. The proposed technologies should be reliable, reproducible and cost effective for the long-term preservation and revival of wild type and laboratory created genetic stocks. (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - January 31, 2018 Category: Research Source Type: funding

Discovery of the Genetic Basis of Childhood Cancers and of Structural Birth Defects: Gabriella Miller Kids First Pediatric Research Program (X01, Clinical Trials Not Allowed)
Funding Opportunity PAR-18-583 from the NIH Guide for Grants and Contracts. As part of the Gabriella Miller Kids First Pediatric Research Program (Kids First), the NIH invites applications to use submit samples from pediatric cohorts for whole genome sequencing at a Kids First-supported sequencing center. Applicants are encouraged to propose sequencing of existing pediatric cancer cohorts to elucidate the genetic contribution to childhood cancers, or to expand the range of disorders included within the Kids First Data Resource to investigate the genetic etiology of structural birth defects. Whole genome, exome, and transc...
Source: NIH Funding Opportunities (Notices, PA, RFA) - January 16, 2018 Category: Research Source Type: funding